Daniela Cristina Melo Magalhães (AC19-5A99-46A9)

Curriculum Vitae

Daniela Cristina Melo Magalhães

Daniela Melo Magalhães has a bachelor degree on Biology and a Master´s degree on Molecular Biology and Genetics. The Master’s thesis aimed to study the progression of neuroninflmmatory markers in the organotypic hippocampal slice model of epileptogenesis. Currently, Daniela is taking a PhD in integrative Neurosciences at the Faculdade de Medicina da Universidade de Lisboa. Her project focus on elucidating the molecular mechanism underlying the social isolation in a mice model. The project is been undertaking between Instituto de Medicina Molecular – João Lobo Antunes and University of Brighton, United Kingdom

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Identification

Personal identification

Full name: Daniela Cristina Melo Magalhães

Citation names

Daniela M Magalhães

Author identifiers

Ciência ID: AC19-5A99-46A9
ORCID iD: 0000-0002-1662-2002

Email addresses

dani.crist90@gmail.com (Professional)
dmagalhaes@medicina.ulisboa.pt (Professional)

Addresses

Instituto de Medicina Molecular. Av. Prof. Egas Moniz, 1649-028 , Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

Medical and Health Sciences - Basic Medicine - Neurosciences
Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2018/01/01 - 2020/12/31 Ongoing	PhD in Integrative Neuroscience (Doutoramento) Universidade de Lisboa Faculdade de Medicina, Portugal Instituto de Medicina Molecular, Portugal University of Brighton School of Pharmacy and Biomolecular Sciences, United Kingdom "Can the modulation of the crosstalk between systemic immune system and Central Nervous System ameliorate the depressive and anxiety-like behaviour induced in Social Isolated mice?" (THESIS/DISSERTATION)
2015 Concluded	Biologia Molecular e Genética (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal "Deciphering the role of inflammation in the organotypic hippocampal slice model of epileptogenesis" (THESIS/DISSERTATION)	17
2012 Concluded	Biologia Molecular e Genética (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal "n/a" (THESIS/DISSERTATION)	15

Affiliation

Science

	Category Host institution	Employer
2024/03 - 2024/07	Researcher (Research)	Instituto de Medicina Molecular, Portugal

2015/09/01 - 2016/09/01	Research Trainee (Research)	Instituto de Medicina Molecular, Portugal
	Instituto de Medicina Molecular, Portugal

Projects

Grant

	Designation	Funders
2024/03 - 2024/07	Does the context matter for drug action? Context dependency of the long-lasting neurobiological and antidepressant actions of psilocybin PTDC/MED-FAR/4834/2021 Research Fellow	Ongoing
2017/01/01 - 2021/07/31	Can the modulation of the crosstalk between systemic immune system and Central Nervous System ameliorate the depressive and anxiety-like behaviour induced in Social Isolated mice? PD/BD/128405/2017 PhD Student Fellow Instituto de Medicina Molecular, Portugal Universidade de Lisboa Faculdade de Medicina, Portugal University of Brighton School of Pharmacy and Biomolecular Sciences, United Kingdom	Fundação para a Ciência e a Tecnologia Ongoing

Outputs

Publications

Conference poster	Daniela M Magalhães. "Modulation of Mouse Hippocampal Lipidomic Signature by FTY720, a sphingosine 1-phosphate analogue used for treating relapsing-remitting Multiple Sclerosis". Paper presented in FENS 24, 2024. Daniela M Magalhães. "Social isolation impact on the development of neuropsychiatric disorders and neuroinflammation - an ageing study in a mice mode". Paper presented in ISN-APSN 2022, 2022. Daniela M Magalhães. "Social isolation impact on behaviour and neuroinflammatory context– an aging study in a mice model". Paper presented in FENS 22, 2022. Daniela M Magalhães. "The impact of social isolation on behaviour and glial cells – a study in young and old mice". Paper presented in Glia Network, 2021. Daniela M Magalhães. "The impact of Social Isolation – a study in young and old mice.". Paper presented in BNA Neuroscience Festival, 2021. Daniela M Magalhães; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Immunomodulatory effects of FTY720 in a Social Isolated mice model". Paper presented in 12th FENS Forum of Neuroscience, 2020. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente (BD1B-6720-D51D). "Immunomodulatory effects of FTY720 in a mice model of Social Isolation". Paper presented in Glial Meeting, 2019. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan. "Immunomodulatory effects of FTY720 in the depressive and anxiety-like behaviour in a mice model of Social Isolation". Paper presented in XVI Meeting of the Portuguese Society of Neuroscience, 2019. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Effects of FTY720 in anxiety-like behaviour and neuroinflammation in a mice model of social isolation". Paper presented in BNA Neuroscience Festival, 2019. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Crosstalk modulation between the systemic immune system and CNS in a social isolation model". Paper presented in 3rd Annual Scientific Meeting of SynaNet H2020, 2018. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Effects of FTY720 in a mice model of social isolation". Paper presented in 4th Meeting of Students from the Mind-Brain Doctoral College of the University of Lisbon, 2018. Magalhães, Daniela M; Mythe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Effects of a nootropic and immumodulator drug in a mice model of Social Isolation". Paper presented in Society for Neuroscience 2018, 2018. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Effects of FTY720 in depressive and anxiety-like behaviour in social isolated mice". Paper presented in 11th FENS Forum of Neuroscience, 2018. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Interplay between the systemic immune system and CNS – effects of FTY720 in Social Isolated mice". Paper presented in 2nd Annual Scientific Meeting of SynaNet H2020, 2018. Magalhães, Daniela M; Myrthe Mampay; Sebastião, Ana M; Graham Sheridan; CA Valente. "Can the modulation of the Crosstalk between the Peripheral Immune System and CNS ameliorate the depressive and anxiety-like behaviour induced in social isolated mice?". Paper presented in 3rd Meeting of Students from the Mind-Brain Doctoral College of the University of Lisbon, 2017. Cláudia Beltrão-Cavacas; Daniela M Magalhães; CA Valente; Sebastião, AM. "Characterization of Cell Death in the ex vivo model of Epileptogenesis". Paper presented in 3rd Meeting of Students from the Mind-Brain Doctoral College of the University of Lisbon, 2017. Magalhães, Daniela M; Pereira, Noémia; CA Valente; Sebastião, Ana M. "Progression of inflammatory mediators in the organotypic hippocampal slice model of epileptogenesis". Paper presented in Glial Meeting, 2017. Daniela M Magalhães; Pereira, Noémia; CA Valente; Sebastião, Ana M. "Progression of inflammatory mediators in the organotypic hippocampal slice model of epileptogenesis". Paper presented in 2nd Meeting of the PhD students from the Mind-Brain Doctoral College of the University of Lisbon, 2016. Daniela M Magalhães; Pereira, Noémia; CA Valente; Sebastião, Ana M. "Progression of inflammatory mediators in the organotypic hippocampal slice model of epileptogenesis". Paper presented in 1st Meeting of the PhD students from the Mind-Brain Doctoral College of the University of Lisbon, 2015.
Journal article	Daniela M. Magalhães; Nicolas A. Stewart; Myrthe Mampay; Sara O. Rolle; Chloe M. Hall; Emad Moeendarbary; Melanie S. Flint; et al. "The sphingosine 1-phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus". Journal of Neurochemistry (2024): https://doi.org/10.1111/jnc.16073. 10.1111/jnc.16073 Miguel Farinha-Ferreira; Daniela M. Magalhães; Mariana Neuparth-Sottomayor; Hugo Rafael; Catarina Miranda-Lourenço; Ana M. Sebastião. "Unmoving and uninflamed: Characterizing neuroinflammatory dysfunction in the Wistar-Kyoto rat model of depression". Journal of Neurochemistry (2024): https://doi.org/10.1111/jnc.16083. 10.1111/jnc.16083 Daniela M Magalhães. "Aged-related impact of social isolation in mice: young vs middle-aged.". Journal of Neurochemistry International (2024): Published Magalhães, Daniela M.; Pereira, Noémia; Rombo, Diogo M.; Beltrão-Cavacas, Cláudia; Sebastião, Ana M.; Valente, Cláudia A.. "Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening". Journal of Neuroinflammation 15 1 (2018): http://dx.doi.org/10.1186/s12974-018-1225-2. 10.1186/s12974-018-1225-2
Thesis / Dissertation	Daniela M Magalhães. "Deciphering the role of inflammation in the organotypic hippocampal slice model of epileptogenesis". Master, Universidade de Lisboa - Faculdade de Ciências, 2015. https://repositorio.ul.pt/handle/10451/18227?locale=en.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2018/02/07	Effects of FTY720 in depressive and anxiety-like behaviour in social isolated mice	XLVIII Annual Meeting of the Portuguese Society of Pharmacology Faculdade de Medicina da Universidade de Lisboa (Lisboa, Portugal)
2016/07/04	Characterisation of an ex vivo organotypic slice culture model of epilepsy	(Brighton, United Kingdom)
2015/02/06	Deciphering the progression of inflammatory mediators in rat organotypic hippocampal slice model of epileptogenesis	XLV Anual Meeting of the Portuguese Society of Pharmacology (Lisboa, Portugal)
2014/12/15	Deciphering the role of inflammation in organotypic hippocampal slice model of epileptogenesis	Neurosciences Seminar (Lisboa, Portugal)
2013/12/16	Deciphering the role of Taurine in hyperexcitability	Neurosciences Seminar (Lisboa, Portugal)

Event participation

	Activity description Type of event	Event name Institution / Organization
2020/03/09 - 2020/06/22	Neuropharmcalocogy (discipline from Medicine course) Other	Universidade de Lisboa Faculdade de Medicina, Portugal
2019/06/04 - 2020/06/05	Mass Spectrometry Training Workshop	University of Brighton School of Pharmacy and Biomolecular Sciences, United Kingdom
2020/03/04 - 2020/03/05	Graphic Design Workshop	Graphic Design Universidade de Lisboa Faculdade de Medicina, Portugal
2018/06/11 - 2018/06/15	SynaNet 2018 Summer School: Signals from Brain Workshop
2018/05/21 - 2018/06/08	SynaNet Short Term Mission - Techniques to study Microglia Workshop	Università degli Studi di Roma La Sapienza, Italy
2018/03/08 - 2018/05/18	Scientific Writing: Preparing a hypothesis-driven research paper Workshop	Universidade de Lisboa Faculdade de Medicina, Portugal
2017/12/12 - 2017/12/14	SynaNet Workshop on Basic Flow Cytometry Workshop	Itä-Suomen yliopisto - Kuopion kampus, Finland
2017/10/16 - 2017/10/19	Principles and Applications of Flow Cytometry Course	Instituto de Medicina Molecular, Portugal
2017/09/26 - 2017/09/29	Workshop in Behavioural Models of Disease Workshop	Lancaster University, United Kingdom
2017/09/25 - 2017/09/26	Workshop in Becoming an Effective Researcher Workshop	Lancaster University, United Kingdom
2017/06/27 - 2017/06/28	Workshop in Microglia cells in health and diseases Workshop	Università degli Studi di Roma La Sapienza, Italy
2017/06/07 - 2017/06/09	Workshop in Neuroimaging Workshop	Itä-Suomen yliopisto, Finland
2016/11/04 - 2016/11/06	Bioimaging NanoCourse on Microscopy Workshop	Instituto de Medicina Molecular, Portugal
2016/10/26 - 2016/10/28	Workshop in Neuroinflammation Workshop	Itä-Suomen yliopisto, Finland
2016/02/15 - 2016/02/19	Advanced Course in Bioinformatics Analysis of Biological Sequences Workshop	Universidade de Lisboa - Faculdade de Ciências, Portugal
2014/04 - 2014/05	Laboratory Animal Science Workshop	Instituto de Medicina Molecular, Portugal

Association member

	Society Organization name	Role
2019/01/01 - Current	Sociedade Portuguesa de Neurociências
2017/03/01 - Current	British Neuroscience Association

Distinctions

Award

2022	Awarded with BNA Bursary for FENS 22
2022	Awarded a travel grant for ISN-APSN 22 conference
2021	Joint winner for the traditional student poster prize category presented during the British Neuroscience Association 2021 Festival of Neuroscience.