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Ana Sofia Santos Dias completed her Master's Degree in Biochemistry in 2017 and her PhD in Biochemistry in 2024, both from the University of Aveiro. Ana Sofia has published 5 articles in international journals, presented her work at 12 national and international events, and received 2 awards. Her research focuses on the immunomodulation of Tumor-Associated macrophages in Triple Negative Breast Cancer.
Identification

Personal identification

Full name
Ana Sofia Santos Dias

Citation names

  • Dias, Ana Sofia

Author identifiers

Ciência ID
A91A-1ECC-23BB
ORCID iD
0000-0002-5643-7696

Email addresses

  • a.dias@ua.pt (Professional)

Addresses

  • Universidade de Aveiro: CICECO - Aveiro Institute of Materials, Department of Chemistry. University of Aveiro; Campus de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2018/10/01 - 2024/05/02
Concluded
 Bioquímica (Doutoramento)
Universidade de Aveiro, Portugal
"Reprogramação metabólica de macrófagos educados por tumores da mama" (THESIS/DISSERTATION)
 Aprovado por Unanimidade
2017
Concluded
 Bioquímica (Mestrado integrado)
Major in Clínica
Universidade de Aveiro, Portugal
"Desenvolvimento e validação de um método analítico para a quantificação de GHB-GLUC e de GABA em sangue com fins forenses" (THESIS/DISSERTATION)
 17
2015
Concluded
 Bioquímica (Licenciatura)
Universidade de Aveiro, Portugal
"Análise do perfil metabolómico de macrófagos diferenciados em contacto com diferentes biomateriais " (THESIS/DISSERTATION)
 15
Projects

Grant

Designation Funders
2018/10/01 - 2024/05/02 Metabolic reprogramming of tumor-associated macrophages: from deeper insights to novel therapeutic approaches in triple negative breast cancer
SFRH/BD/140322/2018
PhD Student Fellow
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. Dias, Ana Sofia; Catarina R. Almeida; Luisa A. Helguero; Iola F. Duarte. "Establishment and characterization of cellular models to study breast cancer-associated macrophages". Paper presented in EMBO Workshop: Cancer immunometabolism, 2021.
  2. Dias, Ana Sofia; Catarina R Almeida; Luisa Helguero; Iola Melissa Fernandes Duarte. "Establishment and characterization of cellular models to modulate breast cancer-associated macrophages". Paper presented in Jonadas CICECO, 2020.
  3. Dias, Ana Sofia; Catarina R Almeida; Luisa Helguero; Iola Melissa Fernandes Duarte. "Establishment and characterization of cellular models to modulate breast cancer-associated macrophages". Paper presented in Metabolomics 2020, 2020.
  4. Dias, Ana Sofia; Catarina R Almeida; Luisa Helguero; Iola Melissa Fernandes Duarte. "Establishment and characterization of cellular models to study breast cancer-associated macrophages". Paper presented in Cancer Biology: From basic to translational research - webinar, 2020.
  5. Dias, Ana Sofia; Catarina R Almeida; Luisa Helguero; Iola Melissa Fernandes Duarte. "Metabolic Crosstalk between Human Macrophages and Triple Negative Breast Cancer Cells". Paper presented in 2nd FEBS Advanced Lecture Course on Oncometabolism-From Conceptual Knowledge to Clinical Applications, 2019.
  6. Dias, Ana Sofia; Catarina R Almeida; Luisa Helguero; Iola Melissa Fernandes Duarte. "Metabolic reprogramming of tumor-associated macrophages in Triple Negative Breast Cancer". Paper presented in V Post-Graduate Symposium in Biomedicine, 2019.
  7. André Castro; Sónia Tarelho; Dias, Ana Sofia; Paula Melo; Helena Teixeira; João Franco. "1,4-butanediol intoxication: a case report". Paper presented in 56th Conference of the International Association of Forensic Toxicologists (TIAFT 2018 Conference), 2018.
  8. Dias, Ana Sofia; André Castro; Sónia Tarelho; João Franco; Pedro Domingues. "Estudo dos Mecanismos de Fragmentação do GHB-GLUC e do GABA após ionização por Impacto Eletrónico em GC-MS/MS". Paper presented in Biochemistry Day, 2017.
  9. Dias, Ana Sofia; Ana Paula Amorim; Eva Feiteira. "Amorim P, Dias AS, Feiteira E. "Review: Angiotensina II e angiotensina (1-7) e os seus efeitos opostos no músculo esquelético"". Paper presented in Biochemistry Day, University of Aveiro, 2017.
Journal article
  1. Ana S. Dias; Catarina R. Almeida; Luisa Helguero; Iola F Duarte. "Antitumoral Activity and Metabolic Signatures of Dichloroacetate, 6-Aminonicotinamide and Etomoxir in Breast-Tumor-Educated Macrophages". Journal of Proteome Research (2024): http://dx.doi.org/10.1021/acs.jproteome.4c00654.
    10.1021/acs.jproteome.4c00654
  2. Ana S. Dias; Catarina R. Almeida; Luisa A. Helguero; Iola F. Duarte. "Metabolic Reprogramming of Breast Tumor-Educated Macrophages Revealed by NMR Metabolomics". Cancers (2023): https://doi.org/10.3390/cancers15041211.
    10.3390/cancers15041211
  3. Ana S. Dias; Luisa Helguero; Catarina R. Almeida; Iola F. Duarte. "Natural Compounds as Metabolic Modulators of the Tumor Microenvironment". Molecules 26 12 (2021): 3494-3494. https://doi.org/10.3390/molecules26123494.
    10.3390/molecules26123494
  4. Ana Sofia Dias; Catarina R Almeida; Luisa Helguero; Iola Melissa Fernandes Duarte. "Metabolic crosstalk in the breast cancer microenvironment". European Journal of Cancer (2019): https://doi.org/10.1016/j.ejca.2019.09.002.
    10.1016/j.ejca.2019.09.002
  5. André Castro; Dias, Ana; Paula Melo; Sónia Tarelho; João Franco; Helena Teixeira. "Quantification of GHB and GHB-GLUC in an 1,4-butanediol intoxication: A case report". Forensic Science International (2019): http://dx.doi.org/10.1016/j.forsciint.2019.01.035.
    10.1016/j.forsciint.2019.01.035
  6. Ana Sofia Dias; André Castro; Paula Melo; Sónia Tarelho; Pedro Domingues; João Franco. "A fast method for GHB-GLUC quantitation in whole blood by GC-MS/MS (TQD) for forensic purposes". Journal of Pharmaceutical and Biomedical Analysis (2018): http://dx.doi.org/10.1016/j.jpba.2017.11.072.
    10.1016/j.jpba.2017.11.072
Thesis / Dissertation
  1. Dias, Ana Sofia Santos. "Desenvolvimento e validação de um método analítico para a quantificação de GHB-GLUC e de GABA em sangue com fins forenses". Master, 2017. http://hdl.handle.net/10773/22711.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/07/08 Establishment and characterization of cellular models to study breast cancer-associated macrophages Research Summit 2021
University of Aveiro (Aveiro, Portugal)
2020/06 Metabolic Reprogramming of Tumor-Associated Macrophages (TAM) in Triple Negative Breast Cancer Research Summit
Universidade de Aveiro (Aveiro, Portugal)
2019/09 Metabolic Crosstalk between Human Macrophages and Triple Negative Breast Cancer Cells 2nd FEBS Advanced Lecture Course on Oncometabolism-From Conceptual Knowledge to Clinical Applications
(Luso, Portugal)
2019/07 Metabolic Reprogramming of Tumor-Associated Macrophages: from Deeper Insights to Novel Therapeutic Approaches in Triple Negative Breast Cancer Research Summit
Universidade de Aveiro (Aveiro, Portugal)
2017/11 Desenvolvimento e validação de um método analítico em GC-MS/MS para a quantificação de GHB-GLUC em sangue tota 16º Congresso Nacional de Medicina Legal e Ciências Forenses/ 1ª Reunião da Rede de Serviços Médico-Legais de Língua Portuguesa
Universidade de Coimbra (Coimbra, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2020/09/25 - Current Attendance at the Webinar "Cancer Biology: From biology basic to translational research" Cancer Biology: From biology basic to translational research
Liga Portuguesa Contra o Cancro, Portugal
2019/09/11 - Current Attendance at the "1st Iberian Seminar on NMR Metabolomics in Clinical Research"
Seminar
 1st Iberian Seminar on NMR Metabolomics in Clinical Research
Universidade de Aveiro, Portugal
2019/04/29 - Current Science Dissemination- Celebrations of the International Day of Immunology with Fábrica Ciência Viva, University of Aveiro, Laboratory sessions for High school children
Workshop
 Celebrations of the International Day of Immunology - Laboratory Sessions
Fábrica Ciência Viva, Portugal
2018/10 - Current Attendance at the "10th Symposium in metabolism: Immunometabolism"
Symposium
 10th Symposium in metabolism: Immunometabolisim
Universidade do Porto Faculdade de Medicina, Portugal
2022/02/23 - 2022/02/23 Event with seminars from invited speakers and presentations of projects of clinical investigation developed at University of Aveiro.
Conference
 MEDISIS Open Day 2022
Universidade de Aveiro, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
2021/11/29 - 2021/12/01 Attendace at EMBO Workshop: Cancer immunometabolism
Congress
 EMBO Workshop: Cancer immunometabolism
2021/10/06 - 2021/10/07 Attendance at Jornadas CICECO 21 - Advancing Science Shaping Society Jornadas CICECO 21
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
2021/06/12 - 2021/06/12 Science Dissemination about Immunology with Fábrica Ciência Viva, University of Aveiro, Laboratory sessions for children
Workshop
 Imunologia trocada por miúdos
Fábrica Ciência Viva, Portugal
2021/04/20 - 2021/04/30 Collaboration in the campaign 'Conversas com Cientistas - Décadas de Ciência para Dias de Vacinas' Conversas com Cientistas - Décadas de Ciência para Dias de Vacinas
Ciência Viva, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Sociedade Portuguesa de Imunologia, Portugal
2020/10/27 - 2020/10/29 Attendace at "Metabolomics 2020"
Conference
 16th Anual Conference - Metabolomics 2020
2020/10/19 - 2020/10/20 Attendance at Jornadas CICECO
Congress
 Jornadas CICECO
Universidade de Aveiro CICECO, Portugal
2019/09/01 - 2019/09/06 Advanced Lecture Course on Oncometabolism 2nd FEBS Advanced Lecture Course on Oncometabolism-From Conceptual Knowledge to Clinical Applications
Distinctions

Award

2021 Travel Grant for EMBO Workshop - Cancer Immunometabolism
2019 Biochimica et Biophysica Acta -Molecular Basis of Disease (BBA-MBD) bursary