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I, Ana Emanuela, am pursuing a PhD in Biomedical Sciences at the University Institute of Health Sciences (IUCS) – Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), under the supervision of Doctor Professor Sara Ricardo. Her doctoral research focuses on understanding the role of the tumor microenvironment in ovarian cancer, particularly the effect of malignant ascites on disease progression and chemoresistance . Her team actually works in the development of patient-derived organoids as advanced three-dimensional models to explore tumor plasticity and identify potential biomarkers and therapeutic targets in platinum-resistant disease. I hold a Master’s degree in Oral Rehabilitation (2021) from the University of São Paulo (USP), where I investigated the physicomechanical properties of dental biomaterials and the interaction between surface characteristics and biological response in prosthetic devices. I earned my undergraduate degree in Dentistry from the Federal University of Ceará (UFC) in 2018, where I began my scientific path through research on Computer-Aided Design / Computer-Aided Manufacturing (CAD/CAM) ceramic systems and tissue biomechanics, contributing to interdisciplinary approaches in bioengineering and materials science. During my academic journey, I received several research and teaching scholarships funded by CAPES and UFC. I actively participated in scientific research and educational training programs and was recognized for my dedication to scientific outreach and collaborative research. As part of her doctoral training, I joined the 1H-TOXRUN – Toxicology Research Unit, where I strengthened my technical expertise in histological analysis, including H&E staining, immunohistochemistry, tissue microarray construction, and microtomy, among others. successfully applied cell culture development in vitro and ex vivo models using cell lines and patient-derived cultures, specifically for drug testing and viability assays. I also contributed to protocol optimization and lab training for new researchers. I authored and co-authored peer-reviewed articles and presented her work at leading national and international conferences, including the International Association for Dental Research / American Association for Dental Research / Canadian Association for Dental Research (IADR/AADR/CADR) and General Session and the Brazilian Society for Dental Research (SBPqO). I also served as an Ad Hoc reviewer for the Scientific Journal of the Public Health School of Ceará (ESP) and contributed to the publication of book chapters, broadening her impact in scientific communication. In academia, I served as an assistant professor and lecturer in Brazil, teaching courses in Histology, Anatomy, Clinical Diagnosis, and Prosthodontics. I also worked at both technical and higher education levels, where I combined theoretical instruction with hands-on clinical mentoring, developing strong pedagogical and leadership skills. In addition to my academic and scientific contributions, I was involved in international and civic activities. Indeed, I completed professional development courses at The Language Gallery in London, United Kingdom, and I volunteered with the United Nations’ Global Combat COVID-19 Support Centre, participating in global public health support initiatives during the pandemic. My academic and professional journey reflects a strong commitment to interdisciplinary research, biomedical innovation, and translational oncology. My work integrates cancer biology, toxicology, and pharmacology, with the aim of contributing to more effective and personalized therapeutic strategies for ovarian cancer.
Identification

Personal identification

Full name
Ana Emanuela Cisne de Lima

Citation names

  • Lima, Ana

Author identifiers

Ciência ID
A317-1551-3570
ORCID iD
0000-0002-0931-1978
Google Scholar ID
https://scholar.google.com/citations?user=GIHPbMcAAAAJ&hl=en

Telephones

Mobile phone
  • 912549687 (Personal)

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Social Biomedical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2024/11/04 - 2028/11/06
Ongoing
PhD in Biomedical Sciences (Doutoramento)
Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
2019/03/01 - 2021/07/28
Concluded
M.S. in Oral Rehabilitation (Master)
Major in Dental Materials and Prosthesis
Universidade de São Paulo, Brazil
"Specific Brushes for Total Prostheses - Characteristics of the Brushes and Effects on a Thermally Activated Acrylic Resin" (THESIS/DISSERTATION)
19
2014/03/01 - 2018/12/20
Concluded
Dentistry (Bachelor (1st cycle))
Major in General
Universidade Federal do Ceará, Brazil
"Evaluation of Mechanical Properties of CAD/CAM Ceramic Systems: Literature Review" (THESIS/DISSERTATION)
16
Affiliation

Science

Category
Host institution
Employer
2020/05 - 2020/05 Science and Technology Management Escola de Saude Publica do Ceara, Brazil

Teaching in Higher Education

Category
Host institution
Employer
2022/09 - 2023/05 Adjunct Teacher (Polytechnic Teacher) Colégio Elite, Brazil
2022/04 - 2023/01 Invited Assistant Professor (University Teacher) Centro Universitário Christus, Brazil

Positions / Appointments

Category
Host institution
Employer
2022/07 - 2022/11 Prosthetist Specialist - Clinical care of geriatric dentistry and oral rehabilitation. Odontocenter, Brazil
2021/01 - 2021/09 Supervisor of Professional Education - Oral Health Technician Professional Education Coordination - CEPAE, Brazil
Outputs

Publications

Book chapter
  1. Ana Emanuela Cisne de Lima; Gabriela Frajtag; Leonardo Holanda Lima; Stéfani Diniz; Marília Zottis Mingotti; Caroline Serafim Dagostin. "Organization in the Home Office: Where to Start?". Brazil, 2020.
    10.29327/515257
Journal article
  1. Lima, Ana; Arruda, Carolina Noronha Ferraz de; Goyeneche, Daniel Zuluaga; Oliveira, Viviane de Cássia; Macedo, Ana Paula; Silva-Lovato, Cláudia Helena; Paranhos, Helena de Freitas Oliveira. Corresponding author: Arruda, Carolina Noronha Ferraz de. "Evaluation of the bristle characteristics and effects of denture brushes on acrylic resin". Acta Scientiarum. Health Sciences 47 (2025): e68071. https://doi.org/10.4025/actascihealthsci.v47i1.68071.
    Published • 10.4025/actascihealthsci.v47i1.68071
  2. "Evaluation of mechanical properties of CAD/CAM ceramic systems: literature review". RGO - Revista Gaúcha de Odontologia 68 (2020): http://dx.doi.org/10.1590/1981-863720200003820200009.
    10.1590/1981-863720200003820200009
  3. "FREQUÊNCIA DE ACIDENTES PERFUROCORTANTES EM DENTISTAS DE SOBRAL-CE". Cadernos ESP - Revista Cientí­fica da Escola de Saúde Pública do Ceará (2020): https://cadernos.esp.ce.gov.br/index.php/cadernos/article/view/300.
Activities

Event participation

Activity description
Type of event
Event name
Institution / Organization
2025/04/09 - 2025/04/09 I participated in a webinar led by Dr. Ayse Güven, focused on the application of human organoids in preclinical studies. The session covered strategies for using intestinal, hepatic, and airway organoids in drug screening, toxicity assessment, barrier integrity, metabolism, and antiviral efficacy, highlighting their translational potential in drug development.
Other
Webinar sobre Organoides e Modelos Teciduais Avançados na Descoberta de Fármacos
STEMCELL Technologies Inc, Canada

Ad Hoc journal article review

Journal title (ISSN) Publisher
2021/05 - 2021/05 Escola de Saúde Pública do Ceará - ESP (1808-7329 (1809-0893)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/09 - 2023/05 Oral health promotion and prevention Oral anatomy technical course in oral health (Postgraduate Certificate) Colégio Elite, Brazil
2022/04 - 2023/01 Preceptorship and guidance in clinical and practical activities. Postgraduate Course Prosthesis (Postgraduate Certificate) Centro Universitário Christus, Brazil