Carolina Campos Silva (A015-3AE3-F93B)

Curriculum Vitae

Carolina Campos Silva

Graduated in Nutrition from the Federal University of Ouro Preto, Brazil, I came to Portugal to do master's degree in Consummer Sciences and Nutrition, at the Faculty of Nutrition and Food Sciences at the University. I completed my master's degree at the end of 2012 and in 2013 I applied to the doctoral program in Metabolism - Clinic and Experimentation, at the Faculty of Medicine of UP. During the PhD, I decided to investigated about Diabetes trying to understand the vascular dysfunction and metabolic imbalance presents in diabetic milieu. The focus of my work was to study the angiogenic paradox existing on heart and kidney of diabetic patients, in celular and animal model, as well as analysing the profile of genes altered in the group. The theme is vast and allowed me to develop technical and laboratory skills never worked before (molecular, cellular, histology, etc.), which generated a great personal and professional learning.

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Identification

Personal identification

Full name: Carolina Campos Silva

Citation names

Silva, Carolina

Author identifiers

Ciência ID: A015-3AE3-F93B

Email addresses

carolsilvapdmce@gmail.com (Professional)

Addresses

Al. Prof. Hernâni Monteiro, 4200 - 319, Porto, Porto, Portugal (Professional)

Knowledge fields

Medical and Health Sciences - Health Sciences - Nutrition, Dietetics

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)

Education

	Degree	Classification
2013/12/07 - 2019/05/15 Concluded	Metabolism - Clinical and Experimental (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal "TARGETING THE ENDOTHELIAL CELL METABOLISM AND FUNCTION CROSSTALK AS A MEANS TO UNRAVEL THE ANGIOGENIC PARADOX IN TYPE 1 DIABETES MELLITUS" (THESIS/DISSERTATION)	Approved
2015/06 - 2015/07/03 Concluded	Essential Molecular Biology - Hands-on Laboratory (Pós-Graduação) Major in Biologia Molecular Universidade do Porto Faculdade de Medicina, Portugal	13
2014/06 - 2014/06 Concluded	Laboratory Animal Sciences - Category B (Pós-Graduação) Universidade do Porto Faculdade de Medicina, Portugal
2010/10 - 2012/10 Concluded	Consumer Science and Nutrition (Mestrado) Universidade do Porto Faculdade de Ciências da Nutrição e Alimentação, Portugal "Desenvolvimento de um Recipiente Edível à base de Arroz-doce e o Impacto na Glicemia Pós-Prandial da adição de Canela neste tipo de Doce" (THESIS/DISSERTATION)	15
2004/08/01 - 2009/09 Concluded	Nutrition (Graduado) Universidade Federal de Ouro Preto Escola de Nutrição, Brazil	8.1

Affiliation

Science

	Category Host institution	Employer
2020/10/16 - 2021/06/30	Research Assistant (Research)	Universidade do Porto Faculdade de Medicina, Portugal

Others

	Category Host institution	Employer
2019/06/15 - 2019/12/31	Researcher	Fundação para a Ciência e a Tecnologia, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2013/12 - 2019/05/31	PHD Student	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil
	Universidade do Porto Faculdade de Medicina, Portugal

Projects

Grant

	Designation	Funders
2019/06/15 - 2019/12/31	Projeto Estratégico I3S (UID/BIM/04293/2019) UID/BIM/04293/2019 Researcher Universidade do Porto Faculdade de Medicina, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded
2016 - 2019/05	Bioengineered therapies for infectious disease and tissue regeneration (NORTE_01_0145_FEDER_000012 595000 2016-2019) NORTE_01_0145_FEDER_000012 595000 2016-2019) PhD Student Fellow Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Faculdade de Medicina, Portugal	Concluded
2013/12 - 2019/05	Ciências sem Fronteiras 99999.010010/2013-00 PhD Student Fellow Universidade do Porto Faculdade de Medicina, Portugal	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Concluded

Outputs

Publications

Journal article

Silva, Carolina; Andrade, Sara; Rodrigues, Ilda; Costa, Raquel; Soares, Raquel. "Metformin reduces vascular assembly in high glucose-treated human microvascular endothelial cells in an AMPK-independent manner". Cell Journal (2021):
Open access • Accepted
Silva, Carolina; Rodrigues, Ilda; Costa, Raquel; Sampaio-Pinto, Vasco; Andrade, Sara; Nascimento, Diana. "Establishing a Link Between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model". Cellular Physiology and Biochemistry 52 3 (2019): 503-516. http://dx.doi.org/10.33594/000000036.
Open access • Published • 10.33594/000000036
Costa, Raquel; Rodrigues, Ilda; Guardão, Luísa; Rocha-Rodrigues, Sílvia; Silva, Carolina; Magalhães, José; Ferreira-de-Almeida, Manuel; Negrão, Rita; Soares, Raquel. "Xanthohumol and 8-prenylnaringenin ameliorate diabetic-related metabolic dysfunctions in mice". The Journal of Nutritional Biochemistry 45 (2017): 39-47. http://dx.doi.org/10.1016/j.jnutbio.2017.03.006.
10.1016/j.jnutbio.2017.03.006

Magazine article

Silva, Carolina; Soares, Raquel; Costa, Raquel; Rodrigues, Ilda. "Efeito da metformina na formação de estruturas capilares em HMEC-1 expostas à condições de hiperglicemia", Revista Portuguesa de Diabetes, 2019
Silva, Carolina. "Effects of AICAR, Compound C and Metformin administration in metabolic and angiogenic behavior in human microvascular endothelial cells (HMECs)", Revista Portuguesa de Diabetes, 2019
Silva, Carolina. "Endothelial metabolism impacts on vascular behaviour in type 1 diabetic mice", Revista Portuguesa de Diabetes, 2019
Silva, Carolina; Rodrigues, Ilda; Sampaio-Pinto, Vasco; Nascimento, Diana; Pinto-do-Ó, Perpétua; Soares, Raquel; Andrade, Sara. "Paradoxo Angiogénico na Diabetes tipo 1: Análise da expressão de genes associados ao metabolismo e angiogénese.", Revista Portuguesa de Diabetes., 2018
Silva, Carolina. "Unveiling metabolic cues in type 1 diabetes vascular complications. The endothelial cell as a target", Revista Portuguesa de Diabetes, 2016

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2018/03	Paradoxo angiogénico na Diabetes tipo 1: Análise da expressão de genes associados ao metabolismo e angiogénese.	14º Congresso Portugues de Diabetes Sociedade Portuguesa de Diabetes (Vilamoura, Portugal)

Event organisation

	Event name Type of event (Role)	Institution / Organization
2015/06 - 2015/10	Organisation of Event (2015/10/21) Symposium (Member of the Organising Committee)	Universidade do Porto Faculdade de Medicina, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2020/03/06 - 2020/03/08	Metformin inhibits angiogenesis and humec-1 collagen formation in hyperglycemia conditions - Poster presentation Congress	16th Portuguese Congress of Diabetes Sociedade Portuguesa de Diabetologia, Portugal
2019/10/30 - 2019/10/30	Attendant Symposium	11th Metabolism Symposium – Ageing and Metabolism. Universidade do Porto Faculdade de Medicina, Portugal
2019/03/08 - 2019/03/10	Efeito da metformina na formação de estruturas capilares expostas à condições de hiperglicemia - Poster presentation Congress	15th Portuguese Diabetes Congress Sociedade Portuguesa de Diabetologia, Portugal
2018/10/17 - 2018/10/17	Effects of AICAR, Compound C and Metformin administration in metabolic and angiogenic behavior in human microvascular endothelial cells (HMECs) - Poster presentation Symposium	10th Symposium of Metabolism Universidade do Porto Faculdade de Medicina, Portugal
2018/10/17 - 2018/10/17	Endothelial metabolism impacts on vascular behaviour in type 1 diabetic mice - Poster presentation Symposium	10th Symposium of Metabolism Universidade do Porto Faculdade de Medicina, Portugal
2017/10/25 - 2017/10/25	Attendant Meeting	6th Doctoral Students Meeting Universidade do Porto Faculdade de Medicina, Portugal
2017/10/18 - 2017/10/18	Attendant Symposium	9th Metabolism Symposium - Metabolic Syndrome and its relationship with Cardiovascular Disease and Cancer Universidade do Porto Faculdade de Medicina, Portugal
2017/07/05 - 2017/07/05	Attendant Meeting	1st DBM Scientific Meeting. Universidade do Porto Faculdade de Medicina, Portugal
2017/03/02 - 2017/03/03	Attendant Conference	VII Conference on Risk Factors and Primary Health Guidelines Universidade do Porto Faculdade de Medicina, Portugal
2016/11/18 - 2016/11/20	Attendant Congress	20th Portuguese Obesity Congress - “OBESITY, A Priority”
2016/10/19 - 2016/10/19	Attendant Symposium	8th Metabolism Symposium - “Metabolic Programming” Universidade do Porto Faculdade de Medicina, Portugal
2016/05/19 - 2016/05/20	Attendant Congress	XV Congress of Nutrition and Food Associação Portuguesa dos Nutricionistas, Portugal
2016/03/30 - 2016/03/30	Attendant Seminar	Iodine & Health Seminar Universidade do Porto Faculdade de Medicina, Portugal
2016/03/17 - 2016/03/20	Attendant Congress	12th Portuguese Diabetes Congress Sociedade Portuguesa de Diabetologia, Portugal
2016/03/11 - 2016/03/11	Relationship Between Angiogenesis and Metabolism in Diabetes - Poster presentation Meeting	5th Doctoral Students Meeting Universidade do Porto Faculdade de Medicina, Portugal
2015/02/27 - 2015/02/28	Attendant Meeting	Annual Meeting of Diabetology Poruguese Society Sociedade Portuguesa de Diabetologia, Portugal
2014/10/22 - 2014/10/25	Attendant Congress	9th Annual CardioMetabolic Health Congress Medical Education Resources Inc, United States

Distinctions

Award

2020	Pedro Eurico Lisboa Award, Honorable Mention for the paper "Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model" Sociedade Portuguesa de Diabetologia, Portugal