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Identification

Personal identification

Full name
Luís Filipe Oliveira da Maia

Author identifiers

Ciência ID
9F1E-51AF-C38B
ORCID iD
0000-0002-8140-3471

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
Education
Degree Classification
2010/05 - 2015/03
Concluded
 Neurobiology (Doutoramento)
Major in CSF and Plasma biomarkers in mouse models of neurodegenerative diseases.
Hertie Institute for Clinical Brain Research, University of Tübingen, Germany
"Cerebrospinal fluid biomarkers of Alzheimer’s Disease: Cerebral ß-amyloidosis mouse models as relevant translational tools" (THESIS/DISSERTATION)
 N/A
1998
Concluded
 Medicina (Licenciatura)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"N/A" (THESIS/DISSERTATION)
 15/20
Affiliation

Science

Category
Host institution 		Employer
2015/06/15 - 2020 Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2015 - 2020 Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010/05/01 - 2014/09/30 Visiting Researcher (Research) Hertie Institute for Clinical Brain Research, University of Tübingen, Germany
Hertie Institute for Clinical Brain Research, University of Tübingen, Germany
2005/01/01 - 2005/07/01 Visiting Researcher (Research) The University of British Columbia Department of Medicine Division of Neurology, Canada
The University of British Columbia Department of Medicine Division of Neurology, Canada

Teaching in Higher Education

Category
Host institution 		Employer
2016/09/01 - 2020 Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Others

Category
Host institution 		Employer
2014/06/01 - 2020 Assistente Hospitalar de Neurologia Centro Hospitalar Universitário do Porto EPE, Portugal
2010/05/01 - 2014/05/31 PhD Student Hertie Institute for Clinical Brain Research, University of Tübingen, Germany
2006/06/01 - 2010/04/30 Assistente Hospitalar de Neurologia Centro Hospitalar Universitário do Porto EPE, Portugal
2001/01/01 - 2006/03/01 Interno Complementar de Neurologia Centro Hospitalar Universitário do Porto EPE, Portugal
1998/07/01 - 2000/12/31 Investigador estagiário Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Outputs

Publications

Journal article
  1. "Early plasma biomarker dynamic profiles are associated with acute ischemic stroke outcomes". European Journal of Neurology (2022): http://dx.doi.org/10.1111/ene.15273.
    10.1111/ene.15273
  2. Marta Francisca Corrà; Nuno Vila-Chã; Ana Sardoeira; Clint Hansen; Ana Paula Sousa; Inês Reis; Firmina Sambayeta; et al. "Peripheral neuropathy in Parkinson’s disease: prevalence and functional impact on gait and balance". Brain (2022): https://doi.org/10.1093/brain/awac026.
    10.1093/brain/awac026
  3. "Timely and Blood-Based Multiplex Molecular Profiling of Acute Stroke". Life 11 8 (2021): 816-816. http://dx.doi.org/10.3390/life11080816.
    10.3390/life11080816
  4. "Advantages of an Automated Method Compared With Manual Methods for the Quantification of Intraepidermal Nerve Fiber in Skin Biopsy". Journal of Neuropathology & Experimental Neurology (2021): http://dx.doi.org/10.1093/jnen/nlab045.
    10.1093/jnen/nlab045
  5. Oliveira, Vanessa; Seabra, Mafalda; Rodrigues, Rita; Carvalho, Vanessa; Mendes, Michel; Pereira, Diogo; Caldeiras, Catarina; et al. "Neuro-COVID frequency and short-term outcome in the Northern Portuguese population". European Journal of Neurology (2021): http://dx.doi.org/10.1111/ene.14874.
    Published • 10.1111/ene.14874
  6. "Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium". JAMA Network Open 4 5 (2021): e2112131-e2112131. http://dx.doi.org/10.1001/jamanetworkopen.2021.12131.
    10.1001/jamanetworkopen.2021.12131
  7. Atrsaei, Arash; Corrà, Marta Francisca; Dadashi, Farzin; Vila-Chã, Nuno; Maia, Luis; Mariani, Benoit; Maetzler, Walter; Aminian, Kamiar. "Gait speed in clinical and daily living assessments in Parkinson’s disease patients: performance versus capacity". npj Parkinson's Disease 7 1 (2021): http://dx.doi.org/10.1038/s41531-021-00171-0.
    Accepted • 10.1038/s41531-021-00171-0
  8. Maia, LF. "Primary prevention of COVID-19: advocacy for vaccination from a neurological perspective.". European journal of neurology (2021): https://doi.org/10.1111/ene.14713.
    10.1111/ene.14713
  9. Corrà, Marta Francisca; Warmerdam, Elke; Vila-Chã, Nuno; Maetzler, Walter; Maia, Luís. "Wearable Health Technology to Quantify the Functional Impact of Peripheral Neuropathy on Mobility in Parkinson’s Disease: A Systematic Review". Sensors 20 22 (2020): 6627. http://dx.doi.org/10.3390/s20226627.
    Published • 10.3390/s20226627
  10. Maia, LF. "EAN consensus statement for management of patients with neurological diseases during the COVID-19 pandemic.". European journal of neurology (2020): https://europepmc.org/articles/PMC7675361.
    10.1111/ene.14521
  11. Maia, LF. "The international European Academy of Neurology survey on neurological symptoms in patients with COVID-19 infection.". European journal of neurology (2020): https://europepmc.org/articles/PMC7323212.
    10.1111/ene.14407
  12. Natoli, Silvia; Oliveira, Vanessa; Calabresi, Paolo; Maia, Luis F.; Pisani, Antonio. "Does SARS-Cov-2 invade the brain? Translational lessons from animal models". European Journal of Neurology (2020): http://dx.doi.org/10.1111/ene.14277.
    In press • 10.1111/ene.14277
  13. Geritz, Johanna; Maetzold, Sara; Steffen, Maren; Pilotto, Andrea; Corrà, Marta F.; Moscovich, Mariana; Rizzetti, Maria C.; et al. "Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment – the ComOn-study". BMC Geriatrics 20 1 (2020): http://dx.doi.org/10.1186/s12877-020-1445-z.
    Published • 10.1186/s12877-020-1445-z
  14. Maia, Luis. "Plasma neurofilament light chain: an early biomarker for hereditary ATTR amyloid polyneuropathy.". Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis (2020): https://doi.org/10.1080/13506129.2019.1708716.
    10.1080/13506129.2019.1708716
  15. Maia, Luis. "Oral anticoagulation in patients with "hemorrhagic-prone" vasculopathies: Overestimated risk?". Neurology (2019): https://doi.org/10.1212/WNL.0000000000007537.
    10.1212/wnl.0000000000007537
  16. Maia, Luis. "Efficiency of silencing RNA for removal of transthyretin V30M in a TTR leptomeningeal animal model.". (2016):
  17. Maia, Luis. "Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases.". (2016):
  18. Martins J; Santos E; Salgado P; Maia L; Dias D; Marta M; França M. "Recurrent cerebrospinal fluid escape in an HIV-1-infected patient receiving antiretroviral therapy.". (2016): http://europepmc.org/abstract/med/27028145.
    10.1097/QAD.0000000000001037
  19. Maia LF; Kaeser SA; Reichwald J; Lambert M; Obermüller U; Schelle J; Odenthal J; et al. "Increased CSF Aß during the very early phase of cerebral Aß deposition in mouse models.". (2015): http://europepmc.org/abstract/med/25978969.
    10.15252/emmm.201505026
  20. Maia L. "Emerging CNS involvement in FAP-TTR long survival patients.". (2015): http://europepmc.org/abstract/PMC/PMC4642080.
  21. Fritschi SK; Langer F; Kaeser SA; Maia LF; Portelius E; Pinotsi D; Kaminski CF; et al. "Highly potent soluble amyloid-ß seeds in human Alzheimer brain but not cerebrospinal fluid.". (2014): http://europepmc.org/abstract/med/25212850.
    10.1093/brain/awu255
  22. Maia LF; Magalhães R; Freitas J; Taipa R; Pires MM; Osório H; Dias D; et al. "CNS involvement in V30M transthyretin amyloidosis: clinical, neuropathological and biochemical findings.". (2014): http://europepmc.org/abstract/med/25091367.
  23. Coelho T; Maia LF; da Silva AM; Cruz MW; Planté-Bordeneuve V; Suhr OB; Conceiçao I; et al. "Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy.". (2013): http://europepmc.org/abstract/med/23974642.
    10.1007/s00415-013-7051-7
  24. Maia LF; Kaeser SA; Reichwald J; Hruscha M; Martus P; Staufenbiel M; Jucker M. "Changes in amyloid-ß and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein.". (2013): http://europepmc.org/abstract/med/23863834.
    10.1126/scitranslmed.3006446
  25. Coelho T; Maia LF; Martins da Silva A; Waddington Cruz M; Planté-Bordeneuve V; Lozeron P; Suhr OB; et al. "Tafamidis for transthyretin familial amyloid polyneuropathy: a randomized, controlled trial.". (2012): http://europepmc.org/abstract/med/22843282.
    10.1212/WNL.0b013e3182661eb1
  26. Taipa R; Moreira B; França M; Maia LF. "A case of haemophagocytic syndrome presenting with oculogyric crises.". (2010): http://europepmc.org/abstract/med/20360170.
    10.1136/jnnp.2009.177097
  27. Feldman HH; Maia LF; Mackenzie IR; Forster BB; Martzke J; Woolfenden A. "Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease.". (2008): http://europepmc.org/abstract/med/18635858.
    10.1161/STROKEAHA.107.510826
  28. Maia LF; Mackenzie IR; Feldman HH. "Clinical phenotypes of Cerebral Amyloid Angiopathy.". (2007): http://europepmc.org/abstract/med/17341423.
    10.1016/j.jns.2007.01.054
  29. Hirsch-Reinshagen V; Chan JY; Wilkinson A; Tanaka T; Fan J; Ou G; Maia LF; et al. "Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-beta peptide levels in vivo.". (2007): http://europepmc.org/abstract/med/17235115.
    10.1194/jlr.M600543-JLR200
  30. Maia LF; Marta M; Lopes V; Rocha N; Lopes C; Martins-da-Silva A; Monteiro L. "Hypersomnia in Whipple disease: case report.". (2006): http://europepmc.org/abstract/med/17057900.
    10.1590/S0004-282X2006000500030
  31. Maia LF; Vasconcelos C; Seixas S; Magalhães R; Correia M. "Lobar brain hemorrhages and white matter changes: Clinical, radiological and laboratorial profiles.". (2006): http://europepmc.org/abstract/med/16691025.
    10.1159/000093245
  32. Hirsch-Reinshagen V; Maia LF; Burgess BL; Blain JF; Naus KE; McIsaac SA; Parkinson PF; et al. "The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.". (2005): http://europepmc.org/abstract/med/16207707.
    10.1074/jbc.M508781200
  33. Vasconcelos MH; Maia LF; Sousa C; Beleza SS; Guimarães JE. "Evidence for a specific intracellular localization of an antisense oligonucleotide in k562 cells.". (2005): http://europepmc.org/abstract/med/16141637.
    10.1254/jphs.SCE05001X
  34. Maia LF; Botelho L; Correia MM. "Commentary on 'Subcortical hematoma caused by cerebral amyloid angiopathy: does the first evidence of hemorrhage occur in the subarachnoid space?' (Neuropathology 2003; 23, 254-261).". (2004): http://europepmc.org/abstract/med/15641599.
    10.1111/j.1440-1789.2004.00586.x
  35. Vasconcelos MH; Beleza SS; Quirk C; Maia LF; Sambade C; Guimarães JE. "Limited synergistic effect of antisense oligonucleotides against bcr-abl and transferrin receptor mRNA in leukemic cells in culture.". (2000): http://europepmc.org/abstract/med/10773404.
    10.1016/S0304-3835(99)00441-3
Distinctions

Award

2017 Prémio Sollari Allegro - trabalho de Investigação
Centro Hospitalar Universitário do Porto EPE, Portugal
2017 Hertie Institute for Clinical Brain Research “Paper of the year award 2017”
Hertie Institute for Clinical Brain Research, University of Tübingen, Germany
2007 First prize of Sociedade Portuguesa de Genética Humana.(ex-aequo)
Sociedade Portuguesa de Genética Humana, Portugal
2006 Novartis Prize 2005
Sociedade Portuguesa de Neurologia, Portugal
2005 Best Poster - Pathology Day
2003 3rd Prize of Liga Portuguesa contra a Epilepsia 2003
1999 Best Poster