Diana Alexandra Vieira Campos (9C16-DC7E-D8AA)

Curriculum Vitae

Diana Alexandra Vieira Campos

Researcher with 10+ years experience in Glycobiology and Cancer Research. Diana Campos (DC) is a BSc in Biochemistry and MSc in Molecular Oncology by the University of Porto with an awarded international PhD fellowship by FCT to conduct her 5 years research in Copenhagen Center for Glycomics (University of Copenhagen). DC obtained the PhD degree in Biomedicine in 2015 and spent 1 year Post-doctoral training at Lombardi Cancer Centre, Georgetown University, Washington DC, then joining the Glycobiology in Cancer group at I3S, University of Porto. DC has a total of 15 publications in international journals (impact factor ranging from 3.5 to 22.8), including most recent publications in Cancer Cell (2019) and, as first author, in Trends in Cancer (2020). She was the main supervisor of a MSc student (thesis). She was invited to teach a course at Faculty of Medicine and participated in outreach activities such as CienciaViva. She was awarded funding and the participation in RESOLVE Program 2017 and HiSeedTech Program 2018, which promote translational and management skills for scientists.

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Identification

Personal identification

Full name: Diana Alexandra Vieira Campos

Citation names

Campos, Diana

Author identifiers

Ciência ID: 9C16-DC7E-D8AA
ORCID iD: 0000-0003-0762-7124
Scopus Author Id: 56370794500

Email addresses

Diana.Campos@mpi-bn.mpg.de (Professional)

Addresses

Ludwingsstraße 43, 61231, Bad Nauheim, Bad Nauheim, Germany (Professional)

Websites

https://orcid.org/0000-0003-0762-7124 (Professional)

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2015 Concluded	Doctor's Degree in Biomedicine (Doutoramento) Kobenhavns Universitet Institut for Cellular og Molekylar Medicin, Denmark Universidade do Porto Faculdade de Medicina, Portugal "A glycoproteomics discovery strategy for gastric cancer biomarkers" (THESIS/DISSERTATION)	Approved with Distinction
2010 Concluded	Master degree in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Kobenhavns Universitet Institut for Cellular og Molekylar Medicin, Denmark "Biomarkers for early detection of gastric cancer based on autoantibodies signatures." (THESIS/DISSERTATION)	18 out of 20
2008 Concluded	Biochemistry (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal "Definition of the Functional RCK Domain of KtrAB Ion Transporter. " (THESIS/DISSERTATION)	16 out of 20

Affiliation

Science

	Category Host institution	Employer
2022/02/01 - Current	Postdoc (Research)	Max-Planck-Institut für Herz- und Lungenforschung W G Kerckhoff-Institute, Germany

2019/01/01 - 2021/12/31	Researcher (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

2016/07/01 - 2018/12/31	Postdoc (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

2015/04/01 - 2016/06/01	Postdoc (Research)	Georgetown University, United States

2011/04/01 - 2015/03/31	Researcher (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Kobenhavns Universitet Institut for Cellular og Molekylar Medicin, Denmark
2009/04/01 - 2010/08/30	Researcher (Research)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

2010/04/01 - 2010/06/30	Researcher (Research)	Kobenhavns Universitet Institut for Cellular og Molekylar Medicin, Denmark

2008/02/01 - 2008/07/30	Research Trainee (Research)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2019 - 2019	Lecturer (University Teacher)	Universidade do Porto Faculdade de Medicina, Portugal

Projects

Grant

	Designation	Funders
2019/01/01 - Current	Identification of Novel GlycoSpecific Drugs to Tackle Cancer Cell Metastasis. POCI-01-0145-FEDER-029780 Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2016/07/01 - 2018/12/31	Cellular glycoengineering for evaluation of post-translational modifications of receptors in cancer: theragnostic applications. PTDC/BBB-EBI/0567/2014 Post-doc Fellow Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia
2015/05 - 2016/06	Alliance of Glycobiologists for Detection of Cancer U01 CA168926 Post-doc Fellow Georgetown Lombardi Comprehensive Cancer Center, United States Georgetown University, United States	National Institutes of Health Clinical Center
2015/05 - 2016/06	Basic Cancer Research in Cancer Health Disparities U01 CA171146 Post-doc Fellow Georgetown Lombardi Comprehensive Cancer Center, United States Georgetown University, United States	National Institutes of Health
2013/06 - 2015/09	Zinc-finger nuclease-glycoengineered SimpleCell lines for characterization of the O-glycoproteome of cancer cells. grant.Provided by PTCRIS: 125428 Research Fellow	Fundação para a Ciência e a Tecnologia
2011/01 - 2015/03	A Glycoproteomics discovery strategy for gastric cancer biomarkers SFRH/ BD/ 73717/2010 PhD Student Fellow Kobenhavns Universitet Institut for Cellular og Molekylar Medicin, Denmark Universidade do Porto Faculdade de Medicina, Portugal	Fundação para a Ciência e a Tecnologia
2009/01 - 2012/03	Early detection of cancer using serum biomarkers based on aberrant post-translational modifications of O-glycoproteins, O-PTM-Biomarkers. grant.Provided by PTCRIS: 82716 Research Fellow Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia

Other

	Designation	Funders
2018/01 - 2018/11	HiSeedTech - GlycoDiagnostic HiSeedTech Principal investigator Universidade do Porto Porto Business School, Portugal
2017/01 - 2018/01	Resolve Program - GlycoTarget resolve program Principal investigator Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Outputs

Publications

Journal article

Costa, Ana Filipa; Campos, Diana; Reis, Celso A.; Gomes, Catarina. "Targeting Glycosylation: A New Road for Cancer Drug Discovery". Trends in Cancer 6 9 (2020): 757-766. http://dx.doi.org/10.1016/j.trecan.2020.04.002.
10.1016/j.trecan.2020.04.002
Moreira; Pinto; Gomes; Campos; Reis. "Impact of Truncated O-glycans in Gastric-Cancer-Associated CD44v9 Detection". Cells 9 2 (2020): 264. http://dx.doi.org/10.3390/cells9020264.
Accepted • 10.3390/cells9020264
Paiva, Joana S.; Jorge, Pedro A. S.; Ribeiro, Rita S. R.; Balmaña, Meritxell; Campos, Diana; Mereiter, Stefan; Jin, Chunsheng; et al. "iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-59661-5.
10.1038/s41598-020-59661-5
Gomes, C.; Almeida, A.; Barreira, A.; Calheiros, J.; Pinto, F.; Abrantes, R.; Costa, A.; et al. "Carcinoembryonic antigen carrying SLe^X as a new biomarker of more aggressive gastric carcinomas". Theranostics 9 24 (2020): 7431-7446. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074719039&partnerID=MN8TOARS.
10.7150/thno.33858
Paiva, J.S.; Jorge, P.A.S.; Ribeiro, R.S.R.; Balmaña, M.; Campos, D.; Mereiter, S.; Jin, C.; et al. "Author Correction: iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification (Scientific Reports, (2020), 10, 1, (3171), 10.1038/s41598-020-59661-5)". Scientific Reports 10 1 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087067571&partnerID=MN8TOARS.
10.1038/s41598-020-67916-4
Freitas D; Balmaña M; Poças J; Campos D; Osório H; Konstantinidi A; Vakhrushev SY; Magalhães A; Reis CA. "Different isolation approaches lead to diverse glycosylated extracellular vesicle populations.". Journal of extracellular vesicles (2019): http://europepmc.org/abstract/med/31236201.
10.1080/20013078.2019.1621131
Neves, M.; Azevedo, R.; Lima, L.; Oliveira, M.I.; Peixoto, A.; Ferreira, D.; Soares, J.; et al. "Exploring sialyl-Tn expression in microfluidic-isolated circulating tumour cells: A novel biomarker and an analytical tool for precision oncology applications". New Biotechnology 49 (2019): 77-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054441529&partnerID=MN8TOARS.
10.1016/j.nbt.2018.09.004
Freitas, D.; Campos, D.; Gomes, J.; Pinto, F.; Macedo, J.A.; Matos, R.; Mereiter, S.; et al. "O-glycans truncation modulates gastric cancer cell signaling and transcription leading to a more aggressive phenotype". EBioMedicine 40 (2019): 349-362. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060115866&partnerID=MN8TOARS.
10.1016/j.ebiom.2019.01.017
Steentoft, C.; Fuhrmann, M.; Battisti, F.; Van Coillie, J.; Madsen, T.D.; Campos, D.; Halim, A.; et al. "A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: Identification of a novel dysadherin-Tn antibody". Glycobiology 29 4 (2019): 307-319. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063274001&partnerID=MN8TOARS.
10.1093/glycob/cwz004
Mereiter, S.; Balmaña, M.; Campos, D.; Gomes, J.; Reis, C.A.. "Glycosylation in the Era of Cancer-Targeted Therapy: Where Are We Heading?". Cancer Cell 36 1 (2019): 6-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067650826&partnerID=MN8TOARS.
10.1016/j.ccell.2019.06.006
Gipson, I.K.; Mandel, U.; Menon, B.; Michaud, S.; Tisdale, A.; Campos, D.; Clausen, H.. "Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16". Glycobiology 27 10 (2017): 920-926. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031118898&partnerID=MN8TOARS.
10.1093/glycob/cwx054
Campos D; Freitas D; Gomes J; Magalhães A; Steentoft C; Gomes C; Vester-Christensen MB; et al. "Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.". (2015): http://europepmc.org/abstract/med/25813380.
10.1074/mcp.m114.046862
Campos, D.; Freitas, D.; Gomes, J.; Reis, C.A.. "Glycoengineered cell models for the characterization of cancer O-glycoproteome: An innovative strategy for biomarker discovery". Expert Review of Proteomics 12 4 (2015): 337-342. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937207849&partnerID=MN8TOARS.
10.1586/14789450.2015.1059758
Marcos-Silva, L.; Narimatsu, Y.; Halim, A.; Campos, D.; Yang, Z.; Tarp, M.A.; Pereira, P.J.B.; et al. "Characterization of binding epitopes of CA125 monoclonal antibodies". Journal of Proteome Research 13 7 (2014): 3349-3359. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903719796&partnerID=MN8TOARS.
10.1021/pr500215g
Gomes, C.; Osório, H.; Pinto, M.T.; Campos, D.; Oliveira, M.J.; Reis, C.A.. "Expression of ST3GAL4 Leads to SLe ^x Expression and Induces c-Met Activation and an Invasive Phenotype in Gastric Carcinoma Cells". PLoS ONE 8 6 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84879165131&partnerID=MN8TOARS.
10.1371/journal.pone.0066737
Reis, C.A.; Campos, D.; Osório, H.; Santos, L.L.. "Glycopeptide microarray for autoantibody detection in cancer". Expert Review of Proteomics 8 4 (2011): 435-437. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051756126&partnerID=MN8TOARS.
10.1586/epr.11.30

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2018/07	GlycoDiagnostic - A diagnostic test for stomach cancer https://www.youtube.com/watch?v=n7m4xM3e_bE&feature=youtu.be	HiSeedTech. Porto Business School
2017/09	The role of glycosylation in the modulation of cancer cell aggressiveness	24th International Symposium On Glycoconjugates.
2017/07	Glycosylation in cancer: glycomic strategies for characterization of molecular functions and biomarker applications	European Carbohydrate Symposium
2017/07	Glycoproteomic strategies for the identification of novel biomarkers in gastric câncer	Mucins in Health and Disease
2016/11	The role of the glycoproteome alterations in gastric cancer and its clinical applications	Annual Meeting Of The Society For Glycobiology
2015/09	Role of glycans in gastric cancer: functional and biomarker applications	23rd International Symposium On Glycoconjugates
2015/09	Biological impact of simple O-Glycans in gastric cancer using Glycoengineered cells	CNIO Frontiers Meeting 2016
2015/07	Glycoproteomic strategies targeting Sialyl-Tn in gastric cancer for biomarker discovery	Mucins in Health and Disease King’s College London

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2018/09 - 2019/12	Impact of truncated O-glycans in cancer associated CD44 variants. Supervisor	Biochemistry for Health (Master) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2019 - 2019	Glycoconjugate Journal (1573-4986)	Springer-Verlag
2018 - 2018	PLoS ONE (1932-6203)	Public Library of Science
2016 - 2016	Molecular & Cellular Proteomics (1535-9484)	American Society for Biochemistry and Molecular Biology

Mentoring / Tutoring

	Topic	Student name
2018 - 2018	Ciencia Viva program	Ciencia Viva students

Distinctions

Award

2018	Project GlycoDiagnostic, a diagnostic test for gastric cancer Universidade do Porto Porto Business School, Portugal
2017	RESOLVE Program - Monoclonal antibodies targeting abnormal, cancer-specific epitopes for innovative diagnostic and therapy strategies for GC patients.
2017	Sao Paulo Research Foundation (FAPESP) grant for Sao Paulo School of Advanced Science Mass Spectrometry (SPSAS-MS) training course 2017. Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil
2014	First Poster Prize presentation 2014 9th International Symposium on Glycosyltransferases.

Other distinction

2017	FELASA for laboratory animal science training for scientists (Category C)