Personal identification

Full name
Maria de Fátima Pinto Brandão

Citation names

  • Brandão, Fátima

Author identifiers

Ciência ID
Degree Classification
Ciências Biomédicas (Doutoramento)
Major in Sem especialidade
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Establishing grouping strategies according to toxicity and biological effets for silica-based manufactured nanomaterials." (THESIS/DISSERTATION)


Host institution
2015/10/01 - Current Researcher (Research) Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal


Designation Funders
2013/07 - 2015/06 Neurotoxicity of mercury in fish and association with morphofunctional brain alterations and behavior shifts Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2011/12 BiOtoMetal - Multidisciplinary assessment of aquatic environment by anthropogenic contaminants (METALs), using a combined BIOmarker - OTOlith chemical analysis approach in fishes Fundação para a Ciência e a Tecnologia, I.P.


  1. Laffon, B.; Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Teixeira, J.P.; Pásaro, E.; Valdiglesias, V.. Cellular and molecular toxicity of iron oxide nanoparticles. 2018.
  2. Kiliç, G.; Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Teixeira, J.P.; Pásaro, E.; Laffon, B.; Valdiglesias, V.. The Application, Neurotoxicity, and Related Mechanism of Iron Oxide Nanoparticles. 2016.
Conference paper
  1. Brandão, Maria. "Cytotoxicity of iron oxide nanoparticles with different coatings on human neuronal cells". 2014.
    DOI: 10.1016/j.toxlet.2014.06.673
  2. Brandão, Maria. "Micronucleus Frequencies In Lymphocytes And Buccal Cells In Formaldehyde Exposed Workers". 2013.
  3. Brandão, Maria. "Should the use of cholinesterase inhibition in environmental analyses be questioned? Studies with metallic compounds on a freshwater fish species Gambusia halbrooki.". 2011.
Journal article
  1. Maria João Bessa; Fátima Brandão; Micaela Machado Querido; Carla Costa; Cristiana Costa Pereira; Vanessa Valdiglesias; Blanca Laffon; et al. "Optimization of the harvesting and freezing conditions of human cell lines for DNA damage analysis by the alkaline comet assay". Mutation Research/Genetic Toxicology and Environmental Mutagenesis (2018): https://doi.org/10.1016/j.mrgentox.2018.12.002.
  2. Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Kiliç, G.; Duarte, J.A.; Teixeira, J.P.; Pásaro, E.; Valdiglesias, V.; Laffon, B.. "Toxicological assessment of silica-coated iron oxide nanoparticles in human astrocytes". Food and Chemical Toxicology 118 (2018): 13-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046666243&partnerID=MN8TOARS.
  3. Dorier, M.; Tisseyre, C.; Dussert, F.; Béal, D.; Arnal, M.-E.; Douki, T.; Valdiglesias, V.; et al. "Toxicological impact of acute exposure to E171 food additive and TiO2 nanoparticles on a co-culture of Caco-2 and HT29-MTX intestinal cells". Mutation Research - Genetic Toxicology and Environmental Mutagenesis (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85057114479&partnerID=MN8TOARS.
  4. Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Kiliç, G.; Teixeira, J.P.; Pásaro, E.; Laffon, B.; Valdiglesias, V.. "Neurotoxicity assessment of oleic acid-coated iron oxide nanoparticles in SH-SY5Y cells". Toxicology 406-407 (2018): 81-91. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048548036&partnerID=MN8TOARS.
  5. Cardoso, O.; Puga, S.; Brandão, F.; Canário, J.; O'Driscoll, N.J.; Santos, M.A.; Pacheco, M.; Pereira, P.. "Oxidative stress profiles in brain point out a higher susceptibility of fish to waterborne divalent mercury compared to dietary organic mercury". Marine Pollution Bulletin 122 1-2 (2017): 110-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020904750&partnerID=MN8TOARS.
  6. Costa, C.; Brandão, F.; Bessa, M.J.; Costa, S.; Valdiglesias, V.; Kiliç, G.; Fernández-Bertólez, N.; et al. "In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests". Journal of Applied Toxicology 36 3 (2016): 361-372. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955703748&partnerID=MN8TOARS.
  7. Pereira, R.; Guilherme, S.; Brandão, F.; Raimundo, J.; Santos, M.A.; Pacheco, M.; Pereira, P.. "Insights into neurosensory toxicity of mercury in fish eyes stemming from tissue burdens, oxidative stress and synaptic transmission profiles". Marine Environmental Research 113 (2016): 70-79. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954228028&partnerID=MN8TOARS.
  8. Cappello, T.; Brandão, F.; Guilherme, S.; Santos, M.A.; Maisano, M.; Mauceri, A.; Canário, J.; Pacheco, M.; Pereira, P.. "Insights into the mechanisms underlying mercury-induced oxidative stress in gills of wild fish (Liza aurata) combining 1H NMR metabolomics and conventional biochemical assays". Science of the Total Environment 548-549 (2016): 13-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954357978&partnerID=MN8TOARS.
  9. Brandão, F.; Cappello, T.; Raimundo, J.; Santos, M.A.; Maisano, M.; Mauceri, A.; Pacheco, M.; Pereira, P.. "Unravelling the mechanisms of mercury hepatotoxicity in wild fish (Liza aurata) through a triad approach: Bioaccumulation, metabolomic profiles and oxidative stress". Metallomics 7 9 (2015): 1352-1363. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940885109&partnerID=MN8TOARS.
  10. Nunes, B.; Brandão, F.; Sérgio, T.; Rodrigues, S.; Gonçalves, F.; Correia, A.T.. "Effects of environmentally relevant concentrations of metallic compounds on the flatfish Scophthalmus maximus: Biomarkers of neurotoxicity, oxidative stress and metabolism". Environmental Science and Pollution Research 21 12 (2014): 7501-7511. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902532495&partnerID=MN8TOARS.
  11. Brandão, F.P.; Pereira, J.L.; Gonçalves, F.; Nunes, B.. "The impact of paracetamol on selected biomarkers of the mollusc species Corbicula fluminea". Environmental Toxicology 29 1 (2014): 74-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890447827&partnerID=MN8TOARS.
  12. Brandão, F.; Correia, A.T.; Gonçalves, F.; Nunes, B.. "Effects of anthropogenic metallic contamination on cholinesterases of Gambusia holbrooki". Marine Pollution Bulletin 76 1-2 (2013): 72-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886093081&partnerID=MN8TOARS.
  13. Brandão, F.P.; Rodrigues, S.; Castro, B.B.; Gonçalves, F.; Antunes, S.C.; Nunes, B.. "Short-term effects of neuroactive pharmaceutical drugs on a fish species: Biochemical and behavioural effects". Aquatic Toxicology 144-145 (2013): 218-229. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887001552&partnerID=MN8TOARS.
  14. Rodrigues, S.; Antunes, S.C.; Brandão, F.P.; Castro, B.B.; Gonçalves, F.; Nunes, B.. "Effects of anticholinesterase drugs on biomarkers and behavior of pumpkinseed, Lepomis gibbosus (Linnaeus, 1758)". Journal of Environmental Monitoring 14 6 (2012): 1638-1644. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864292263&partnerID=MN8TOARS.


2019 Prémio Melhor Apresentação Oral com o trabalho "Toxicity of different classes of manufactured nanomaterials in rat alveolar epithelial RLE-6TN cells"
Taylor and Francis Group, United Kingdom