Rita Azevedo Sousa e Silva (991F-C4BF-D9BE)

Curriculum Vitae

Rita Azevedo Sousa e Silva

Rita Sousa e Silva is a research trainee in Cell Reprogramming and Development Hematopoiesis group. As a research assistant in the same group, she will be focused on identifying neoantigens (the antigens derivate from cancer cell mutations) using cell reprogramming approaches. Rita has a bachelor´s degree in Biochemistry from Faculdade de Ciências Universidade do Porto (FCUP) and Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto (ICBAS-UP) in 2019 and follows her studies with a master's degree in Cellular and Molecular Biology, concluding in 2021, in FCUP. In her master thesis, she studies the SCA3 disease, using bioinformatics approaches, with a focus on the identification of potential therapeutic targets for this neurological disorder. Further, confirmations of Drosophila melanogaster as a good model species for SCA3 were also addressed. So far, Rita Sousa e Silva participated in 11 events and has two conference abstracts and one research article published. Rita's knowledge fields are Immunology, Neurosciences, Bioinformatics, Biochemistry, and Cell and Molecular Biology.

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Identification

Personal identification

Full name: Rita Azevedo Sousa e Silva

Citation names

Sousa e Silva, Rita

Author identifiers

Ciência ID: 991F-C4BF-D9BE
ORCID iD: 0000-0003-1443-5518

Email addresses

rita.silva.1998@gmail.com (Professional)
ritassilva@i3s.up.pt (Professional)
ritasilva@cnc.uc.pt (Professional)

Addresses

Biocant Park Parque Tecnológico de Cantanhede Núcleo 04, Lote 8, 3060-197, Cantanhede, Cantanhede, Portugal (Professional)

Knowledge fields

Medical and Health Sciences - Basic Medicine - Immunology
Medical and Health Sciences - Basic Medicine - Neurosciences
Exact Sciences - Computer and Information Sciences - Bioinformatics
Natural sciences - Biological Sciences - Biochemistry
Natural sciences - Biological Sciences - Molecular Biology
Natural sciences - Biological Sciences - Cell Biology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2022/08 - 2023/08 Ongoing	Clinical Investigator Certification (CLIC) (Outros) Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022/11 - 2023/03/14 Concluded	Project governance and Project Management Office (Outros) The Open University, United Kingdom
2019/09/12 - 2021/12/06 Concluded	Biologia Celular e Molecular (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal "Drosophila melanogaster as a model for the identification of the ataxin-3 interaction regions" (THESIS/DISSERTATION)	18 (in 20)/ grade B (EU)
2016 - 2019/07/12 Concluded	Bioquímica (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Pathophysiological Role of microRNAs, namely miR-146a, in Pulmonary Arterial Hypertension and Right Ventricle Failure - Therapeutic Implications" (THESIS/DISSERTATION)	16 (in 20)/ grade B (EU)
2017/10/12 - 2017/11/02 Concluded	III Curso de Ciências Forenses (Outros) Universidade do Porto Faculdade de Ciências, Portugal

Affiliation

Science

	Category Host institution	Employer
2023/04/03 - 2024/04/03	Research Assistant (Research)	Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
	Centro de Neurociências e Biologia Celular, Portugal
2023/02/01 - 2023/04/02	Research Trainee (Research)	Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
	Centro de Neurociências e Biologia Celular, Portugal
2022/01 - 2023/01/31	Visiting Researcher (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/07/17 - 2021/12	Research Trainee (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/01 - 2019/07	Research Trainee (Research)	Universidade do Porto Faculdade de Medicina, Portugal
	Universidade do Porto Faculdade de Medicina, Portugal

Other Careers

	Category Host institution	Employer
2022/09 - 2022/12	Professor do ensino básico e secundário (Professor do ensino básico e secundário)	Centro de Estudos Maria Miguel, Portugal

Others

	Category Host institution	Employer
2019/06/24 - 2019/07/07	Monitor in Summer Camp for Children	Associação Cultural e Recreativa Honra e Dever , Portugal

2018/06/24 - 2018/07/07	Monitor in Summer Camp for Children	Associação Cultural e Recreativa Honra e Dever , Portugal

2017/06/24 - 2017/07/07	Monitor in Summer Camp for Children	Associação Cultural e Recreativa Honra e Dever , Portugal

Projects

Grant

	Designation	Funders
2023/04/03 - 2024/04/03	7131 - CiNTech - Technological Hub for Innovation, Translation and Industrialization of Complex Injectable Drugs (CiNTech) 7131 - CiNTech \| 856262 Research Fellow	Governo da República Portuguesa Ongoing

Outputs

Publications

Conference abstract	Sousa, André; Sousa e Silva, Rita; Catarina Vandervoordt; Vieira, Jorge; Cristina P. Vieira. "Drosophila as a SCA3 model: inferences on the Josephin domain role". Paper presented in II INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS, Vila Real, 2021. Published Sousa e Silva, Rita; Sousa, André; Catarina Vandervoordt; Vieira, Jorge; Cristina P. Vieira. "The role of the Josephin domain in the ATXN3 protein interactions". Paper presented in IJUP2021 - 14º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2021. Published
Journal article	Sousa e Silva, Rita; Andre D Sousa; Vieira, Jorge; Cristina P. Vieira. "The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: implications for spinocerebellar ataxia type 3 (SCA3) studies using Drosophila melanogaster mutants". Frontiers in Molecular Neuroscience 16 (2023): Published
Thesis / Dissertation	"Drosophila melanogaster as a model for the identification of the ataxin-3 interaction regions". Master, Universidade do Porto Faculdade de Ciências, 2021. "Pathophysiological Role of microRNAs, namely miR-146a, in Pulmonary Arterial Hypertension and Right Ventricle Failure - Therapeutic Implications". Degree, Universidade do Porto Faculdade de Medicina, 2019.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2021/07/02	Drosophila as a SCA3 model: inferences on the Josephin domain role	II INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS Universidade de Trás-os-Montes e Alto Douro (Vila Real)
2021/05/06	The role of the Josephin domain in the ATXN3 protein interactions	IJUP2021 - 14º Encontro de Investigação Jovem da Universidade do Porto Universidade do Porto (Porto, Portugal)

Event participation

	Activity description Type of event	Event name Institution / Organization
2023/03/29 - 2023/03/31	Immunology annual meeting with several lectures about inflammation, neuroimmunology, tumor immunology, and infection and immunity. Meeting	SPI´48 - Annual Meeting Sociedade Portuguesa de Imunologia, Portugal
2019/11/15 - 2019/11/15	Lectures about Microbiology (therapeutics targets and novel technologies), Immunology, and Oncobiology. Conference	Day of the Microbiology Laboratory Universidade do Porto Faculdade de Farmácia, Portugal
2019/04/12 - 2019/04/15	National meeting for Biochemistry students. Lectures about: Biochemistry, Neurosciences, Animal Experimentation, Astrobiology, Food Sustainability, Oncological Diseases, Drug Administration, among others. Meeting	XII ENEBIOQ I Bioquímica à Beira Ria Universidade de Aveiro, Portugal
2019/04/13 - 2019/04/13	Visit to ECOMARE - Laboratório para a Inovação e Sustentabilidade dos Recursos Biológicos Marinhos da Universidade de Aveiro Workshop	XII ENEBIOQ I Bioquímica à Beira Ria Universidade de Aveiro, Portugal
2019/03/14 - 2019/03/17	Lectures, debates and round tables. National and international speakers. Multidisciplinary themes. Congress	VII AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/03/14 - 2019/03/17	Hands-on Workshop: Inflammatory Response Workshop	VII AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/03/14 - 2019/03/17	Hands-on Workshop: Neuronal circuits nature and optogenetics in Drosophila melanogaster Workshop	VII AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/03/14 - 2019/03/17	Hands-on Workshop: Endocanabinoids - Neurology, pharmacology and therapeutical utility Workshop	VII AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/03/14 - 2019/03/17	Hands-on Workshop: Adult hipoccampal neural plasticity (depression and antidepressants) Workshop	VII AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/09/18 - 2018/09/18	Attend to multiple presentations of PhD students from the Animal Science Doctoral Programme. Workshop	Animal Science Doctoral Programme V Workshop Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/04/07 - 2017/04/10	National meeting for Biochemistry students. Lectures about: Biochemistry, Neurosciences, Legal Medicine, Biomaterials, Animal Experimentation, Food Sustainability, among others. Meeting	X ENEBIOQ A Ciência nas Tuas Mãos Universidade do Minho, Portugal

Association member

	Society Organization name	Role
2022/08 - Current	National Ataxia Foundation (NAF)	Membership focus on SCA3-MJD research

Distinctions

Other distinction

2017	High School Certificate of Excellence Escola Secundária Rocha Peixoto, Portugal