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Carlos Paula holds a PhD in Chemical Engineering (2023) from the Universidade de Coimbra, Faculdade de Ciências e Tecnologia (FCTUC), as well as an MSc (2014) and a BSc (2012) in Biochemistry from the same institution. After a brief period working outside academia, he joined the Polysyc research group at the Department of Chemical Engineering of UC in 2017, working under the supervision of Prof. Jorge Coelho and Prof. Arménio Serra, where he began his research in the field of Polymer Science. Since then, Carlos Paula has published 9 scientific articles in international peer-reviewed journals across various fields, including Polymer Science, Materials Science, Biomaterials, Chemistry, and Biochemistry, and has been involved in 4 research projects. Carlos Paula was also the co-supervisor of 1 BSc thesis in Biomedical Engineering, 1 MSc thesis in Forensic Chemistry, 3 MSc thesis in Biomedical Engineering (UC), and is currently supervising 1 more. During this period, he has been involved in teaching activities and has mentored several students from the MSc in Chemical Engineering. Carlos Paula is currently working as junior researcher at IPN (Instituto Pedro Nunes, Portugal). His scientific expertise is primarily focused on polymer science and biomaterials, with additional experience in organic chemistry, materials science, and biochemistry. His scientific current scientific interests are the synthesis and characterization of polymeric materials (e.g., films, membranes, particles) for biomedical applications or commodities and 3D (bio)printing.
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Identification

Personal identification

Full name
Carlos Tadeu Barreirinhas Paula

Citation names

  • Paula, C. T. B.
  • Paula, C. T.

Author identifiers

Ciência ID
981E-5642-12A4
ORCID iD
0000-0003-2728-160X
Google Scholar ID
https://scholar.google.pt/citations?user=xQooPRcAAAAJ&hl=pt-PT
Scopus Author Id
57217769372

Email addresses

  • ctadeu@eq.uc.pt (Professional)
  • cpaula@ipn.pt (Professional)

Telephones

Telephone
  • (+351) 239 700 83 (Professional)

Addresses

  • Rua Pedro Nunes, 3030 - 199, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Engineering and Technology - Materials Engineering
  • Exact Sciences - Chemical Sciences - Polymer Science

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2018/10/01 - 2023/03/15
Concluded
 Doutoramento em Engenharia Quimica (Doutoramento)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
"Biocompatible hydrogels with controlled degradation by visible light" (THESIS/DISSERTATION)
 Approved with praise and distinction, unanimously
2014
Concluded
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Characterization of new lanthanide complexes and nanoparticles as bimodal imaging agents" (THESIS/DISSERTATION)
 16
2012
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"New perspectives for Nanoparticles in Biomolecular Imaging " (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2023/03/13 - Current Researcher (Research) Instituto Pedro Nunes, Portugal

Others

Category
Host institution 		Employer
2018/09/01 - 2023/02/28 PhD Student Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
2017/01/01 - 2018/08/31 Research Fellow Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
Projects

Grant

Designation Funders
2018/10/01 - 2023/02/28 Biocompatible hydrogels with controlled degradation by visible light
SFRH/BD/136631/2018
PhD Student Fellow
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2017/01/01 - 2018/09/30 Thermocel
SII&DT 3306 THERMOCEL
Research Fellow
Agência Nacional de Inovação SA
Concluded

Contract

Designation Funders
2025/04/01 - Current Minepipe - Desenvolvimento de tubos de alta performance para a indústria mineira
MPr-2023-7 / MPr-2023-8
Researcher
Portugal 2030
2025/03/01 - Current BioDrive - Desenvolvimento de fibras de tecido não tecido (TNT) de fonte renovável para a indústria automóvel.
MPr-2023-7 / MPr-2023-8
Researcher
Portugal 2030
2025/03/01 - Current BioCoating - Desenvolvimento de uma nova tinta biobaseada para indústria automóvel
SIID – I&D Empresarial – Operações em co-promoção- MPr-2023-7 / MPr-2023-8
Researcher
Portugal 2030
2024/11/01 - Current Alchemissts - Alternative Chemicals and Materials integrating Safety, Sustainability, new Production technologies and Socio-economic aspects
HORIZON-CL4-2024-RESILIENCE-01
Researcher
Horizon Europe
Ongoing
2024/07/01 - Current GreenAgro - Desenvolvimento de sistemas de rega completamente biodegradáveis
SIID – I&D Empresarial – Operações em Individual- MPr-2023-7 / MPr-2023-8
Researcher
Instituto Pedro Nunes, Portugal
 Portugal 2030
Ongoing
2023/03/01 - 2024/12/31 Dextran-PCL-based nerve guidance conduits 3D printed for nerve Regeneration
CI22-00190
Researcher
CaixaForum Barcelona
Concluded
2023/03/01 - 2023/06/30 3DNerveGen / Produção de dispositivos médicos biodegradáveis para regeneração nervosa periférica por impressão 3D
Projetos de Ignição e Provas de Conceito INOVC+
Researcher
Concluded
2019/01/01 - 2019/12/31 Centro de Engenharia Mecânica
UID/EMS/00285/2019
Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Porto, Portugal

Universidade de Coimbra, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Paula, C. T.; Medeiros, M.; Pereira, Patrícia; Coelho, Jorge. "3D printing of wound dressing materials using a light-mediated technology". Paper presented in ISMIT 2024, Cáceres, Spain, 2024.
  2. Escobar, Ines; Chaves, Leonor; Pereira, Patrícia; Paula, C. T.; Coelho, Jorge. "Development of a Novel Dextran and PCL-based biomaterial ink for Nerve Regeneration". Paper presented in ISMIT 2024, Cáceres, Spain, 2024.
  3. Saraiva, Sofia; Rénio, Francisca; Santos, Patrícia; Paula, C. T.; Serra, Arménio; Fonseca, Ana C.. "Development of electrospun membranes based on poly(ester amide)s for the prevention of tendon adhesion". Paper presented in Biopol 2024, 2024.
  4. Marques, Maria Leonor; Frias, Célia; Paula, C. T.; Fonseca, Ana C.. "Amino-yne ‘click’ reaction of vegetable oils for biomedical applications". Paper presented in Biopol 2024, 2024.
  5. Saraiva, S.; Pereira, P.; Paula, C. T. B.; Rebelo, R. C.; Coelho, Jorge F.J.; Serra, A. C.; Fonseca, A. C.. "Development of electrospun mats based on hydrophobic hydroxypropyl cellulose derivatives". Paper presented in EPF – European Polymer Congress 2022, 2022.
    10.1016/j.msec.2021.112498
  6. Paula, Carlos T. B.; Pereira, P.; Coelho, Jorge; Fonseca, Ana C.; Serra, Arménio C.. "Biocompatible hydrogels with controlled degradation by visible light". Paper presented in Encontro Ciência 2022, 2022.
  7. Paula, Carlos T. B.; Rebelo, Rafael; Serra, Arménio C.; Coelho, Jorge. "The effect of hydrolyzed cellulose pulp as a filler for LPDE". Paper presented in 31st Materials Science and Engineering Conference: Advancement & Innovations, 2018.
  8. Paula, C. T. B.; Ferreira, Sílvia; Rebelo, Rafael; Serra, Arménio C.; Coelho, Jorge; Pineiro, Marta. "Development of a cellulose based biodegradable material for packaging". Paper presented in 9th World Congress on Green Chemistry and Technology, 2018.
  9. Rebelo, Rafael A. C.; Paula, C. T.; Serra, Arménio; Coelho, Jorge. "Development of a Cellulose based Material for Packaging Applications". Paper presented in Jornada Plástico Sostenible 2018, 2018.
Journal article
  1. Rute Silva; Matilde Medeiros; Carlos T. B. Paula; Sofia Saraiva; Rafael C. Rebelo; Patrícia Pereira; Jorge F. J. Coelho; Arménio C. Serra; Ana C. Fonseca. "Light-Mediated 3D-Printed Wound Dressings Based on Natural Polymers with Improved Adhesion and Antioxidant Properties". Polymers (2025): https://doi.org/10.3390/polym17081114.
    10.3390/polym17081114
  2. Sofia Saraiva; Francisca Rénio; Patrícia Pereira; Patrícia Santos; Carlos T. B. Paula; Amílcar Ramalho; Arménio C. Serra; Ana C. Fonseca. "Tackling the Problem of Tendon Adhesions: Physical Barriers Prepared from a-Amino Acid-Based Poly(ester amide)s". Polymers (2025): https://doi.org/10.3390/polym17030395.
    10.3390/polym17030395
  3. Silva, Rute; Rebelo, Rafael C.; Paula, Carlos T.B.; Pereira, Patrícia; Fonseca, Ana C.; Serra, Arménio C.; Coelho, Jorge F.J.. "All-cellulose resin for 3D printing hydrogels via digital light processing (DLP)". International Journal of Biological Macromolecules (2025): 141389. https://doi.org/10.1016/j.ijbiomac.2025.141389.
    10.1016/j.ijbiomac.2025.141389
  4. Carlos T.B. Paula; Sofia Saraiva; Patrícia Pereira; Jorge F.J. Coelho; Ana C. Fonseca; Arménio C. Serra. "ROS-responsive electrospun poly(amide thioketal) mats for wound dressing applications". Polymer (2024): https://doi.org/10.1016/j.polymer.2024.126697.
    10.1016/j.polymer.2024.126697
  5. Paula, C.T.B.; Leandro, A.; Pereira, P.; Coelho, J.F.J.; Fonseca, A.C.; Serra, A.C.. "Fast-Gelling Polyethylene Glycol/Polyethyleneimine Hydrogels Degradable by Visible-Light". Macromolecular Bioscience (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85172125407&partnerID=MN8TOARS.
    10.1002/mabi.202300289
  6. Paula, Carlos T.B.; Madeira, Ana B.; Pereira, Patrícia; Branco, Rita; Morais, Paula V.; Coelho, Jorge F.J.; Fonseca, Ana C.; Serra, Arménio C.. "ROS-degradable PEG-based wound dressing films with drug release and antibacterial properties". European Polymer Journal 177 (2022): 111447. http://dx.doi.org/10.1016/j.eurpolymj.2022.111447.
    10.1016/j.eurpolymj.2022.111447
  7. Paula, C. T. B.. "Development of light-degradable poly(urethane-urea) hydrogel films". Materials Science and Engineering: C (2021): 112520-112520. http://dx.doi.org/10.1016/j.msec.2021.112520.
    10.1016/j.msec.2021.112520
  8. Sofia Saraiva; Patrícia Pereira; C.T. Paula; R.C. Rebelo; Jorge F.J. Coelho; Arménio C. Serra; Ana C. Fonseca. "Development of electrospun mats based on hydrophobic hydroxypropyl cellulose derivatives". Materials Science and Engineering: C 131 (2021): 112498-112498. https://doi.org/10.1016%2Fj.msec.2021.112498.
    10.1016/j.msec.2021.112498
  9. Carlos T. B. Paula; Rafael C. Rebelo; Jorge Coelho; Arménio C. Serra. "The impact of the introduction of hydrolyzed cellulose on the thermal and mechanical properties of LDPE composites". European Journal of Wood and Wood Products (2019): https://doi.org/10.1007%2Fs00107-019-01457-0.
    10.1007/s00107-019-01457-0
  10. Martins, A.F.; Eliseeva, S.V.; Carvalho, H.F.; Teixeira, J.M.C.; Paula, C.T.B.; Hermann, P.; Platas-Iglesias, C.; et al. "A bis(pyridine N-oxide) analogue of DOTA: Relaxometric properties of the Gd<sup>III</sup> complex and efficient sensitization of visible and NIR-emitting lanthanide(III) cations including Pr<sup>III</sup>and Ho<sup>III</sup>". Chemistry - A European Journal 20 45 (2014): 14834-14845. http://www.scopus.com/inward/record.url?eid=2-s2.0-84915749578&partnerID=MN8TOARS.
    10.1002/chem.201403856
Thesis / Dissertation
  1. "Biocompatible Hydrogels with controlled degradation by visible light". PhD, Universidade de Coimbra Departamento de Engenharia Quimica, 2023. https://hdl.handle.net/10316/114382.
  2. "Characterization of new lanthanide complexes and nanoparticles as bimodal imaging agents". Master, Universidade de Coimbra, 2014. http://hdl.handle.net/10316/28185.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/10 Bioprinting of nerve guide tubes using a DLP technology CELLINK Partenership Conference
CELLINK (Portsmouth, United Kingdom)
2022/07/01 ROS/LIGHT DEGRADABLE POLY(URETHANE-UREA) HYDROGELS FILMS EPF European Polymer Congress 2022
European Polymer Fedaration (Prague, Czech Republic)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025/02/01 - Current Cellulose bioinks for Advanced Wound Healing Applications
Supervisor
 Engenharia Química (Master)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2023/09/01 - 2024/09/30 3D printing of wound dressing materials using a light-mediated technology
Supervisor
 Engenharia Biomédica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2023/08/01 - 2024/02/29 Development of polymeric membranes for the prevention of peritendon adhesions
Co-supervisor
 Engenharia Química (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/09/01 - 2023/09/30 UTILIZAÇÃO DA POLIMERIZAÇÃO EM ESTADO SÓLIDO COMO AUXILIAR NA VISUALIZAÇÃO DE IMPRESSÕES DIGITAIS
Co-supervisor
 Química Forense (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2023/03/01 - 2023/06/30 ROS - RESPONSIVE POLYAMIDE MICROSPHERES FOR THE DEVELOPMENT OF CONTROLLED DRUG DELIVERY SYSTEMS
Co-supervisor
 Engenharia Biomédica (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/09/01 - 2022/09/30 Desenvolvimento de hidrogéis biocompatíveis com degradação controlada por luz visível para aplicação em feridas
Co-supervisor
 MSc in Biomedical Engineering (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/09/01 - 2021/09/30 Development of light degradable hydrogels for wound dressing applications
Co-supervisor
 MSc in Biomedical Engineering (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/11/28 - 2023/11/29 3DBIW - 3D Bioprinting Iberian Workshop (2023/11/28 - 2023/11/29)
Workshop (Member of the Organising Committee)
 CELLINK AB, Sweden

Paralab - Equipamentos Industriais e de Laboratório SA, Portugal

Instituto Pedro Nunes, Portugal
2012/03/30 - 2012/04/02 V Enebioq (2012/03/30 - 2012/04/02)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025/02/20 Poly(ester amide)s based scaffolds for tendon regeneration
(Thesis) Main arguer
 Henrique Gomes Saraiva (Master)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2024/07/22 Combater a doença de Alzheimer usando glicopolímeros
(Thesis) Main arguer
 Joana Pereira da Silva (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2024/02/28 Development of sustainable biodegradable hot-melt adhesives, PhD thesis project
(Thesis) Arguer
 Obinna Remigius Ahamaraeze (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2025/08/03 - Current Coatings (2079-6412) MDPI
2025/08/01 - Current Nature Communications (2041-1723) Nature Publishing Group
2025/04/28 - Current Gels (2310-2861) MDPI
2024/12/15 - Current Polymers (2073-4360) MDPI

Association member

Society Organization name Role
2024/04 - Current Sociedade Portuguesa de Química

Mentoring / Tutoring

Topic Student name
2023/10/01 - 2024/09/30 Amino-yne click reaction of vegetable oils for biomedical applications Maria Leonor Marques
2023/01/01 - 2023/08/31 Micropartículas de poliamida reativas para libertação controlada de fármacos Marta Leonor Gonçalves Correia
Distinctions

Award

2014 Best business idea at Arrisca C/IAPMEI
Universidade de Coimbra, Portugal
2012 The 3% Best Students Award in the academic year 2012/2013
Universidade de Coimbra, Portugal