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Tânia E. Sintra got her MSc degree in Pharmaceutical Sciences at University of Coimbra in 2011. By the middle of 2017 she completed her PhD in Chemistry by University of Aveiro, having during her PhD studies trainee at Faculty of Engineering of the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany. Since then, she is a post-doctoral researcher at CICECO-Aveiro Institute of Materials, University of Aveiro. In 2018, she was awarder with a R&D project (Chiral resolution of drugs in centrifugal partition chromatography using enantioselective aqueous biphasic systems, ChiResus), from the Portuguese Foundation for Science and Technology (FCT), where she is the Principal Investigator (PI). Her last 7 years were dedicated to research on Chemistry and Pharmaceutical areas with focus on organic and analytical chemistry. During her scientific path she have contributed to the development of innovative research in the synthesis of benign ionic liquids to respond to major challenges of pharmaceutical industry, namely the separation of two enantiomers and the lack of aqueous solubility of some promising drugs. Since 2012, Tânia E. Sintra published 24 articles in international peer reviewed scientific journals, with more than 520 citation and an h-index of 13 (data obtained from Scopus at 29th April 2020), and presented several oral and poster communications in national and international conferences.
Identification

Personal identification

Full name
Tânia Ereira Sintra
Date of birth
1987/06/17
Gender
Female

Citation names

  • Sintra, Tânia E.

Author identifiers

Ciência ID
9412-E1DB-EE9A
ORCID iD
0000-0002-7686-5970
Researcher Id
C-1454-2018
Scopus Author Id
55257699700

Email addresses

  • tania.sintra@ua.pt (Professional)

Telephones

Telephone
  • 234370200 Ext.: 33525 (Professional)

Addresses

  • Campus Universitário de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2013/02 - 2017/05
Concluded
Doctoral programme in Chemistry (Doutoramento)
Universidade de Aveiro, Portugal
"Synthesis of more benign ionic liquids for specific applications" (THESIS/DISSERTATION)
Approved
2006/09 - 2011/07
Concluded
Pharmaceutical Sciences (Mestrado integrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
16/20
Affiliation

Science

Category
Host institution
Employer
2017/06/01 - Current Postdoc (Research) Universidade de Aveiro CICECO, Portugal
2016/09/26 - 2016/12/22 Visiting Researcher (Research) Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
2012/06 - 2012/12 Research Trainee (Research) Universidade de Aveiro CICECO, Portugal
2009/06 - 2010/03 Research Trainee (Research) Universidade de Coimbra Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2013/02/01 - 2017/01/31 Synthesis of more benign ionic liquids for specific applications
SFRH/BD/85871/2012
PhD Student Fellow
Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/09 - 2016/12 COST Action CM1206 (EXIL – Exchange on Ionic Liquids)
COST-STSM-CM1206-34926
Invited Scientist Fellow
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
COST Action CM1206 (EXIL – Exchange on Ionic Liquids)
Concluded
2009/01 - 2010/03 Synthesis of Antitumor Action on Steroids with Enzymes Related to Breast and Prostate Cancers
BII/UNI/0177/SAU/2008
Scientific Initiation Fellow
Universidade de Coimbra Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2018/06/01 - 2021/05/31 Chiral resolution of drugs in centrifugal partition chromatography using enantioselective aqueous biphasic systems
PTDC/EQU-EPQ/30750/2017
Principal investigator
Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017/06/01 - 2019/05/31 Project SusPhotoSolutions - Sustainable Photovoltaic Solutions
Post-doc Fellow
Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016/05/01 - 2019/04/30 ToxMix - Toxicity of mixtures of alternative solvents with industrial potential
Researcher
Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2015/10 - 2018/09 Optimization and Scale-up of Novel Ionic-Liquid-based Purification Processes for Recombinant Green Fluorescent Protein produced by Escherichia coli
FAPESP/19793/2014
Researcher
Universidade de Aveiro, Portugal
Fundação de Amparo à Pesquisa do Estado de São Paulo

Fundação para a Ciência e a Tecnologia
Ongoing
2012/06 - 2012/12 [ILTOX] Ecotoxicological evaluation and treatment of aqueous effluents contaminated with ionic liquids
Research Fellow
Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Ferreira, A.M.; Carreira, A.R.F.; Sintra, Tânia E.; Coutinho, J.A.P.. "Biphasic systems as chiral purification platform". Paper presented in Biopartitioning & Purification Conference (BPP 2019), Guarujá, Brazil, 2019.
  2. Sintra, Tânia E.; Shimizu, K.; Ventura, S.P.M.; Shimizu, S.; Canongia Lopes, J.N.; Coutinho, J.A.P.. "Enhanced dissolution of hydrophobic drugs using ionic liquids as hydrotropes". Paper presented in Jornadas CICECO 2019, Aveiro, Portugal, 2019.
  3. Morais, E.S.; Silva, N.N.H.; Sintra, Tânia E.; Santos, S.A.O.; Neves, B.M.; Almeida, I.F.; Costa, P.C.; et al. "Bacterial nanocellulose membranes loaded with phenolic-based ionic liquids for cutaneous application". Paper presented in International Symposium of Green Chemistry (ISGC 2019), La Rochelle, France, 2019.
  4. Sales, I.; Costa, P.; Sintra, Tânia E.; Ventura, S.P.M.; Mattedi, S.; Pinho, S.P.; Freire, M.G.; Coutinho, J.A.P.. "Enhancing Artemisinin Solubility in Aqueous Solutions: Searching for of Ionic Liquids Hydrotropes". Paper presented in International Symposium of Green Chemistry (ISGC2019), La Rochelle, France, 2019.
  5. Soares, B.P.; Sintra, Tânia E.; García, J.I.; Pires, E.; Pinho, S.P.; Coutinho, J.A.P.. "Aqueous solutions of glycerol derived alkyl ethers: the study of hydrotropes in the solubilization of hydrophobic compounds". Paper presented in International Symposium of Green Chemistry (ISGC 2019), La Rochelle, France, 2019.
  6. Sintra, Tânia E.; Shimizu, K.; Ventura, S.P.M.; Shimizu, S.; Canongia Lopes, J.N.; Coutinho, J.A.P.. "Ionic liquids as hydrotropic solubilizing agents for hydrophobic drugs". Paper presented in International Symposium of Green Chemistry (ISGC 2019), La Rochelle, France, 2019.
  7. Sintra, Tânia E.; Kholany, M.; E Silva, F.A.; Ventura, S.P.M.; Coutinho, J.A.P.. "Aqueous biphasic systems based on chiral ionic liquids as platforms for chiral resolution". Paper presented in International Symposium of Green Chemistry (ISGC 2019), La Rochelle, France, 2019.
  8. Martins, M.; Fernandes, A.P.M.; Macário, I.; Bagagem, S.; Sintra, Tânia E.; Pereira, J.; Gonçalves, F.J.M.; Coutinho, J.A.P.; Ventura, S.P.M.. "Sequential extraction and purification of pigments from Anabaena cylindrical". Paper presented in Biopartitioning & Purification Conference (BPP 2019), Guarujá, Brazil, 2019.
  9. Sintra, Tânia; Martins, M.; Macário, I.P.E.; Bagagem, S.S.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.; Ventura, S.P.M.. "Sequential extraction of phycocyanin and chlorophyll from Anabaena cylindrica". Paper presented in 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), Aveiro, Portugal, 2018.
  10. Kholany, M.; E Silva, F.A.; Sintra, Tânia; Ventura, S.P.M.; Coutinho, J.A.P.. "Enantioselective separation of racemic mandelic acid using aqueous biphasic systems with chiral ionic liquids". Paper presented in 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), Aveiro, Portugal, 2018.
  11. Sintra, Tânia; Shimizu, K.; Ventura, S.P.M.; Shimizu, S.; Canongia Lopes, J.N.; Coutinho, J.A.P.. "Enhanced solubilization of hydrophobic drugs using ionic liquids as hydrotropes". Paper presented in 27th Conference on Molten Salts and Ionic Liquids (EuCheMSIL 2018), Lisbon, Portugal, 2018.
  12. Sintra, Tânia; Cruz, D.; Martins, M.; Macário, I.P.E.; Bagagem, S.S.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "Sustainable recovery of phycocyanin from Anabaena cylindrica using aqueous solutions of ionic liquids". Paper presented in 12th Symposium of the European Society of Biochemical Engineering Sciences (ESBES 2018), Lisbon, Portugal, 2018.
  13. Sintra, T.E.; Ventura, S.P.M.; De Morais, P.; Coelho, J.A.S.; Coutinho, J.A.P.; Afonso, C.A.M.. "Ecotoxicological evaluation of furans and their derivatives". Paper presented in Jornadas CICECO 2018, Aveiro, Portugal, 2018.
  14. E Silva, F.A.; Sintra, T.E.; Ventura, S.P.M.; Coutinho, J.A.P.. "Chiral resolution of mandelic acid racemates using aqueous biphasic systems composed of chiral ionic liquids". Paper presented in 3rd International symposium on Green Chemistry (ISGC 2017), La Rochelle, France, 2017.
    10.1063/1.2036783
  15. Sintra, T.E.; Shimizu, K.; Canongia Lopes, J.N.; Ventura, S.P.M.; Coutinho, J.A.P.. "Ionic liquids as catanionic hydrotropes for hydrophobic drugs". Paper presented in 3rd International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT 2017), Kuala Lumpur, Malaysia, 2017.
  16. Sintra, T.E.; Rocha, S.N.; Luís, A.; Lobo Ferreira, A.I.M.C; Gonçalves, A.M.M.; Santos, L.M.N.B.F.; Neves, B.M.; et al. "Enhancing the water solubility and antioxidant properties of phenolic acids by their conversion into cholinium salts". Paper presented in Green Solvents Conference, Kiel, Germany, 2016.
  17. Ventura, S.P.M.; De Morais, P.; Coelho, J.A.S.; Sintra, T.E.; Coutinho, J.A.P.; Afonso, C.A.M.. "Toxicological profile of biomass derived platform chemicals". Paper presented in Green Solvents Conference, Kiel, Germany, 2016.
  18. Sintra, Tânia; Ventura, S.P.M.; Freire, M.G.; Coutinho, J.A.P.. "Ionic liquids as a promising class of catanionic hydrotropes". Paper presented in Green Solvents Conference, Kiel, Germany, 2016.
  19. Cláudio, A.F.M.; Sintra, T.E.; Neves, M.C.; Shimizu, K.; Canongia Lopes, J.N.; Ventura, S.P.M.; Freire, M.G.; Coutinho, J.A.P.. "Ionic liquids as hydrotropes and the enhanced solubilization of hydrophobic compounds on aqueous solutions". Paper presented in Gordon Research Conference - Ionic Liquids for Future Technologies, Newry, ME, United States, 2016.
  20. Sintra, T.E.; Luís, A.; Rocha, S.N.; Lobo Ferreira, A.I.M.C; Gonçalves, F.; Santos, L.M.N.B.F.; Neves, B.M.; et al. "Cholinium salts with increased water-solubility and antioxidant properties". Paper presented in Jornadas CICECO, Aveiro, Portugal, 2016.
  21. Sintra, T.E.; Luís, A.; Rocha, S.N.; Lobo Ferreira, A.I.M.C; Gonçalves, F.; Santos, L.M.N.B.F.; Neves, B.M.; et al. "Cholinium-based salts with enhanced water-solubility and antioxidant properties". Paper presented in 2nd EuCheMS Congress on Green and Sustainable Chemistry, Lisbon, Portugal, 2015.
  22. Sintra, T.E.; Luís, A.; Rocha, S.N.; Lobo Ferreira, A.I.M.C; Gonçalves, F.; Santos, L.M.N.B.F.; Neves, B.M.; et al. "Cholinium-based ionic liquids with antioxidant character". Paper presented in Iberoamerican Meeting on Ionic Liquids (IMIL 2015), Madrid, Spain, 2015.
  23. Vilas, M.; Sintra, T.E.; Ventura, S.P.M.; Santos, L.M.N.B.F.; Lobo Ferreira, A.I.M.C; Gonçalves, F.; Tojo, E.; Coutinho, J.A.P.. "Synthesis and characterization of novel ionic liquids with tensioactive character". Paper presented in Jornadas CICECO 2015, Aveiro, Portugal, 2015.
  24. Vilas, M.; Sintra, T.E.; Ventura, S.P.M.; Santos, L.M.N.B.F.; Lobo Ferreira, A.I.M.C; Gonçalves, F.; Tojo, E.; Coutinho, J.A.P.. "Tensioactive ionic liquids: synthesis and characterization". Paper presented in ECTP - 20th European Conference on Thermophysical Properties, Porto, Portugal, 2014.
  25. Vilas, M.; Sintra, T.E.; Ventura, S.P.M.; Gonçalves, F.; Tojo, E.; Coutinho, J.A.P.. "Ionic liquids with a tensioactive character: their synthesis and characterization". Paper presented in EuChem - Molten Salts and Ionic Liquids XXV, Tallinn, Estonia, 2014.
  26. Sintra, T.E.; Ventura, S.P.M.; Gonçalves, A.M.M.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "Understanding the effect of Iso chemical structures on the toxicity of Ionic Liquids". Paper presented in EuChem - Molten Salts and Ionic Liquids XXV, Tallinn, Estonia, 2014.
  27. Vilas, M.; Sintra, T.E.; Ventura, S.P.M.; Coutinho, J.A.P.. "Synthesis and characterization of new tensioactive ionic liquids". Paper presented in ILSEPT - 2nd International Conference on Ionic Liquids in Separation and Purification Technology, Toronto, Canada, 2014.
  28. E Silva, F.A.; Sintra, T.E.; Ventura, S.P.M.; Coutinho, J.A.P.. "Valorizing pharmaceutical wastes through the recovery of targeted drugs". Paper presented in EXIL Workshop on Liquid/liquid extraction with Ionic Liquids, Strasbourg, France, 2014.
  29. Sintra, T.E.; Ventura, S.P.M.; Gonçalves, A.M.M.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "The impact of the iso chemical structure on the ecotoxicity of ionic liquids". Paper presented in MicroBiotec’13, Aveiro, Portugal, 2013.
  30. E Silva, F.A.; Sintra, T.E.; Ventura, S.P.M.; Coutinho, J.A.P.. "Valorization of pharmaceutical wastes through the recovery of added-value drugs". Paper presented in MicroBiotec’13, Aveiro, Portugal, 2013.
  31. Sintra, T.E.; Ventura, S.P.M.; Gonçalves, A.M.M.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "Towards the sustainable design of ionic liquids: the impact of structural isomerism on their ecotoxicity". Paper presented in REGALIs Summer School, O Grove, Spain, 2013.
  32. Sintra, T.E.; Ventura, S.P.M.; Gonçalves, A.M.M.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "The sustainable design of ionic liquids: their chemical structure impact versus their ecotoxicity". Paper presented in X CICECO Meeting, Aveiro, Portugal, 2013.
  33. Sintra, T.E.; Ventura, S.P.M.; Gonçalves, A.M.M.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "The structure of Ionic liquids and its Impact on their ecotoxicological behavior". Paper presented in 5th Congress on Ionic Liquids, Vilamoura, Portugal, 2013.
  34. Marques, M.P.M. ; Sintra, T.E.; Borges, F.; Tavares da Silva, E. ; Roleira, F.. "Phenolic amides as potential lipophilic antioxidants. a raman spectroscopy study". Paper presented in VI Iberian Congress of Spectroscopy, XXII National Meeting of Spectroscopy (CIE VI, XXII RNE), Porto, Portugal, 2010.
  35. Roleira, F.; Sintra, T.E.; Varela, C.; Correia da Silva, G. ; Cepa, M.; Dias, Ana; Teixeira, N.; Tavares da Silva, Elisiario. "The effect of C-3 stereochemistry in the aromatase inhibitory activity of 3-hydroxy-4-androstenes. A structure-activity study". Paper presented in Frontiers in Medicinal Chemistry: Emerging Targets, Novel Candidates and Innovative Strategies, Barcelona, Spain, 2009.
Journal article
  1. Soares, Bruna P.; Abranches, Dinis O.; Sintra, Tânia E.; Leal-Duaso, Alejandro; García, José Ignacio; Pires, Elísabet; Shimizu, Seishi; Pinho, Simão P.; Coutinho, João A. P.. "Glycerol Ethers as Hydrotropes and Their Use to Enhance the Solubility of Phenolic Acids in Water". ACS Sustainable Chemistry & Engineering 8 14 (2020): 5742-5749. http://dx.doi.org/10.1021/acssuschemeng.0c01032.
    10.1021/acssuschemeng.0c01032
  2. Pereira, Matheus M.; Pedro, Sónia N.; Gomes, Joana; Sintra, Tânia E.; Ventura, Sónia P.M.; Coutinho, João A.P.; Freire, Mara G.; Mohamadou, Aminou. "Synthesis and characterization of analogues of glycine-betaine ionic liquids and their use in the formation of aqueous biphasic systems". Fluid Phase Equilibria 494 (2019): 239-245. http://dx.doi.org/10.1016/j.fluid.2019.05.001.
    10.1016/j.fluid.2019.05.001
  3. Sintra, Tânia E.; Gantman, Mikhail G.; Ventura, Sónia P.M.; Coutinho, João A.P.; Wasserscheid, Peter; Schulz, Peter S.. "Synthesis and characterization of chiral ionic liquids based on quinine, l-proline and l-valine for enantiomeric recognition". Journal of Molecular Liquids 283 (2019): 410-416. http://dx.doi.org/10.1016/j.molliq.2019.03.084.
    Published • 10.1016/j.molliq.2019.03.084
  4. Belchior, Diana C. V.; Almeida, Mafalda R.; Sintra, Tânia E.; Ventura, Sónia P. M.; Duarte, Iola F.; Freire, Mara G.. "Odd–Even Effect in the Formation and Extraction Performance of Ionic-Liquid-Based Aqueous Biphasic Systems". Industrial & Engineering Chemistry Research 58 19 (2019): 8323-8331. http://dx.doi.org/10.1021/acs.iecr.9b00663.
    10.1021/acs.iecr.9b00663
  5. Morais, Eduarda S.; Silva, Nuno H.C.S.; Sintra, Tânia E.; Santos, Sónia A.O.; Neves, Bruno Miguel; Almeida, Isabel F.; Costa, Paulo C.; et al. "Anti-inflammatory and antioxidant nanostructured cellulose membranes loaded with phenolic-based ionic liquids for cutaneous application". Carbohydrate Polymers 206 (2019): 187-197. http://dx.doi.org/10.1016/j.carbpol.2018.10.051.
    10.1016/j.carbpol.2018.10.051
  6. Sintra, Tânia; Vilas, Miguel; Martins, Margarida; Ventura, Sónia; Lobo Ferreira, Ana; Santos, Luís; Gonçalves, Fernando; Tojo, Emília; Coutinho, Joao. "Synthesis and characterization of surface-active ionic liquids used in the disruption of Escherichia coli cells". ChemPhysChem (2019): http://dx.doi.org/10.1002/cphc.201801127.
    Published • 10.1002/cphc.201801127
  7. Francisca A. e Silva; Mariam Kholany; Tânia E. Sintra; Magda Caban; Piotr Stepnowski; Sónia P. M. Ventura; João A. P. Coutinho. "Aqueous Biphasic Systems Using Chiral Ionic Liquids for the Enantioseparation of Mandelic Acid Enantiomers". Solvent Extraction and Ion Exchange (2018): https://doi.org/10.1080/07366299.2018.1545344.
    10.1080/07366299.2018.1545344
  8. Belchior, D.C.V.; Sintra, T.E.; Carvalho, P.J.; Soromenho, M.R.C.; Esperança, J.M.S.S.; Ventura, S.P.M.; Rogers, R.D.; Coutinho, J.A.P.; Freire, M.G.. "Odd-even effect on the formation of aqueous biphasic systems formed by 1-alkyl-3-methylimidazolium chloride ionic liquids and salts". Journal of Chemical Physics 148 19 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85045381104&partnerID=MN8TOARS.
    10.1063/1.5012020
  9. Carlos M. N. Mendonça; Debora T. Balogh; Simone C. Barbosa; Tânia E. Sintra; Sónia P. M. Ventura; Luís F. G. Martins; Pedro Morgado; et al. "Understanding the interactions of imidazolium-based ionic liquids with cell membrane models". Physical Chemistry Chemical Physics (2018): https://doi.org/10.1039/C8CP05035J.
    10.1039/C8CP05035J
  10. Sintra, T.E.; Shimizu, K.; Ventura, S.P.M.; Shimizu, S.; Canongia Lopes, J.N.; Coutinho, J.A.P.. "Enhanced dissolution of ibuprofen using ionic liquids as catanionic hydrotropes". Physical Chemistry Chemical Physics 20 3 (2018): 2094-2103. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040994534&partnerID=MN8TOARS.
    10.1039/c7cp07569c
  11. Sintra, T.E.; Nasirpour, M.; Siopa, F.; Rosatella, A.A.; Gonçalves, F.; Coutinho, J.A.P.; Afonso, C.A.M.; Ventura, S.P.M.. "Ecotoxicological evaluation of magnetic ionic liquids". Ecotoxicology and Environmental Safety 143 (2017): 315-321. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019664958&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2017.05.034
  12. Vicente, F.A.; Cardoso, I.S.; Sintra, T.E.; Lemus, J.; Marques, E.F.; Ventura, S.P.M.; Coutinho, J.A.P.. "Impact of Surface Active Ionic Liquids on the Cloud Points of Nonionic Surfactants and the Formation of Aqueous Micellar Two-Phase Systems". Journal of Physical Chemistry B 121 37 (2017): 8742-8755. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029750430&partnerID=MN8TOARS.
    10.1021/acs.jpcb.7b02972
  13. Ventura, S.P.M.; De Morais, P.; Coelho, J.A.S.; Sintra, T.; Coutinho, J.A.P.; Afonso, C.A.M.. "Evaluating the toxicity of biomass derived platform chemicals". Green Chemistry 18 17 (2016): 4733-4742. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983609914&partnerID=MN8TOARS.
    10.1039/c6gc01211f
  14. Kurnia, K.A.; Sintra, T.E.; Danten, Y.; Cabaço, M.I.; Besnard, M.; Coutinho, J.A.P.. "A simple method for preparation of a novel hydrophobic ionic liquid with a per-fluoro-tert-butoxide anion". New Journal of Chemistry 41 1 (2016): 47-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007206703&partnerID=MN8TOARS.
    10.1039/C6NJ02575G
  15. Das, R.N.; Sintra, T.E.; Coutinho, J.A.P.; Ventura, S.P.M.; Roy, K.; Popelier, P.L.A.. "Development of predictive QSAR models for: Vibrio fischeri toxicity of ionic liquids and their true external and experimental validation tests". Toxicology Research 5 5 (2016): 1388-1399. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983516657&partnerID=MN8TOARS.
    10.1039/c6tx00180g
  16. Sintra, T.E.; Luís, A.; Rocha, S.N.; Ferreira, A.I.M.C.L.; Gonçalves, F.; Santos, L.M.N.B.F.; Neves, B.M.; et al. "Enhancing the antioxidant characteristics of phenolic acids by their conversion into cholinium salts". ACS Sustainable Chemistry and Engineering 3 10 (2015): 2558-2565. http://www.scopus.com/inward/record.url?eid=2-s2.0-84990966169&partnerID=MN8TOARS.
    10.1021/acssuschemeng.5b00751
  17. Lee, S.Y.; Vicente, F.A.; E Silva, F.A.; Sintra, T.E.; Taha, M.; Khoiroh, I.; Coutinho, J.A.P.; Show, P.L.; Ventura, S.P.M.. "Evaluating Self-buffering Ionic Liquids for Biotechnological Applications". ACS Sustainable Chemistry and Engineering 3 12 (2015): 3420-3428. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948951128&partnerID=MN8TOARS.
    10.1021/acssuschemeng.5b01155
  18. Kurnia, K.A.; Sintra, T.E.; Neves, C.M.S.S.; Shimizu, K.; Canongia Lopes, J.N.; Gonçalves, F.; Ventura, S.P.M.; et al. "The effect of the cation alkyl chain branching on mutual solubilities with water and toxicities". Physical Chemistry Chemical Physics 16 37 (2014): 19952-19963. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907059207&partnerID=MN8TOARS.
    10.1039/c4cp02309a
  19. Khan, I.; Kurnia, K.A.; Sintra, T.E.; Saraiva, J.A.; Pinho, S.P.; Coutinho, J.A.P.. "Assessing the activity coefficients of water in cholinium-based ionic liquids: Experimental measurements and COSMO-RS modeling". Fluid Phase Equilibria 361 (2014): 16-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887273582&partnerID=MN8TOARS.
    10.1016/j.fluid.2013.10.032
  20. E Silva, F.A.; Sintra, T.; Ventura, S.P.M.; Coutinho, J.A.P.. "Recovery of paracetamol from pharmaceutical wastes". Separation and Purification Technology 122 (2014): 315-322. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890479152&partnerID=MN8TOARS.
    10.1016/j.seppur.2013.11.018
  21. Sintra, T.E.; Cruz, R.; Ventura, S.P.M.; Coutinho, J.A.P.. "Phase diagrams of ionic liquids-based aqueous biphasic systems as a platform for extraction processes". Journal of Chemical Thermodynamics 77 (2014): 206-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905507991&partnerID=MN8TOARS.
    10.1016/j.jct.2013.10.024
  22. Sintra, T.E.; Ventura, S.P.M.; Coutinho, J.A.P.. "Superactivity induced by micellar systems as the key for boosting the yield of enzymatic reactions". Journal of Molecular Catalysis B: Enzymatic 107 (2014): 140-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903986886&partnerID=MN8TOARS.
    10.1016/j.molcatb.2014.06.001
  23. Ventura, S.P.M.; Gonçalves, A.M.M.; Sintra, T.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.. "Designing ionic liquids: The chemical structure role in the toxicity". Ecotoxicology 22 1 (2013): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871618059&partnerID=MN8TOARS.
    10.1007/s10646-012-0997-x
  24. Ventura, S.P.M.; de Barros, R.L.F.; Sintra, T.; Soares, C.M.F.; Lima, Á.S.; Coutinho, J.A.P.. "Simple screening method to identify toxic/non-toxic ionic liquids: Agar diffusion test adaptation". Ecotoxicology and Environmental Safety 83 (2012): 55-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864079981&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2012.06.002
Thesis / Dissertation
  1. Coutinho, João Pereira; Ventura, Sónia Patrícia Marques; Sintra, Tânia Ereira. "Synthesis of more benign ionic liquids for specific applications". PhD, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22516.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/04 Hydrotropic solubilization of ibuprofen in aqueous solutions of ionic liquids 2nd Advances in Green Chemistry Conference
(Poznan, Poland)
2017/11 Synthesis and characterization of chiral ionic liquids for enantiomeric recognition ABC2 – Anything but Conventional Chromatography
(Lisbon, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2018/02 - 2018/07 Sequential extraction of phycocyanin and chlorophyll from Anabaena cylindrica
Supervisor
Biotechnology (Degree)
Universidade de Aveiro, Portugal
2018/02 - 2018/07 Ionic liquids as a class of catanionic hydrotropes to enhance the solubility of artemisinin
Supervisor
Biotechnology (Degree)
Universidade de Aveiro, Portugal
2014/02 - 2014/07 Synthesis of new cholines with antioxidant properties
Co-supervisor
Chemistry (Degree)
Universidade de Aveiro, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2014/08/31 - 2014/09/04 Active participation in organizing ECTP - 20th European Conference on Thermophysical Properties (2014/08/31 - 2014/09/04)
Conference (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2018/11/15 Extraction and separation of drugs using alternative solvents
(Thesis) Arguer
Ana Francisca Osório de Almeida Coelho e Silva (PhD)
Universidade de Aveiro, Portugal

Conference scientific committee

Conference name Conference host
2018/10/02 - 2018/10/04 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018) Aveiro, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2018/04 - Current Journal of Molecular Liquids (0167-7322) Elsevier
2016 - Current Computational Biology and Chemistry (1476-9271) Elsevier
2015/10 - Current Colloids and Surfaces A: Physicochemical and Engineering ( 0927-7757)