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I received my master's degree in Pharmaceutical Sciences from the Faculty of Pharmacy of the University of Coimbra (FFUC) and I am currently a PhD student in Pharmaceutical Sciences at the same institution. I am developing my work, which is related to the study of circadian rhythms and neurodegenerative diseases, at the Center for Neuroscience and Cell Biology (CNC). I am a member of 2 research groups at CNC (Neuroendocrinology and Aging Group; Vectors and Gene Therapy Group) occasionally working in the Pharmaceutical Chemistry laboratory at FFUC as well. In the context of my PhD, I am also part of the EIT Health Ageing PhD School. In 2023, I received an EMBO Scientific Exchange Grant to work in the research group of Prof. Giorgio Colombo at the Department of Chemistry, University of Pavia, Italy. I have some previous professional experience in the pharmaceutical industry field, particularly in Medical Affairs and R&D. In 2018, I received the award for best oral presentation in basic science at the AstraZeneca Foundation Innovate Competition of the internationally prestigious iMed Conference® 10.0 (Lisbon, Portugal). Between 2017 and 2019, I was a student representative in the Senate of the University of Coimbra and an Editorial Board Member of the Coimbra University Press.
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Identification

Personal identification

Full name
Rodrigo Filipe Nunes Ribeiro

Citation names

  • Ribeiro, Rodrigo
  • Rodrigo F.N. Ribeiro
  • R.F.N.R.
  • Ribeiro, R.F.N.

Author identifiers

Ciência ID
9412-5245-D75C
ORCID iD
0000-0002-5159-4406

Email addresses

  • rodrigo.ribeiro@student.ff.uc.pt (Professional)
  • rribeiro@cnc.uc.pt (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Beginner (A1) Beginner (A1) Elementary (A2) Beginner (A1)
Portuguese (Mother tongue)
Education
Degree Classification
2021/01/24 - 2025/01/24
Ongoing
 EIT Health Ageing PhD School (Doutoramento)
EIT Health, Germany
2019/12/07 - 2024/12/07
Ongoing
 Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/11/14 - 2023/02/17
Concluded
 VI Modular Training in Laboratory Animal Science Function A and Special Skills (theoretical and practical classes) + DGAV (Direção-Geral da Alimentação e Veterinária) accreditation (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
2021/09/06 - 2021/11/01
Concluded
 Frailty in Real-Life and its translational aspects: From I&E to scientific writing (Outros)
Exzellenzcluster CECAD in der Universität zu Köln, Germany
2021/07/12 - 2021/07/17
Concluded
 Computer-Aided Drug Design International Summer School (Outros)
Università degli Studi di Pisa Dipartimento di Farmacia, Italy
2014/09/10 - 2019/09/18
Concluded
 Ciências Farmacêuticas (Mestrado integrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
 16
2014/05/01
Concluded
 Cambridge English Level 1 Certificate in ESOL International (First) - B2 (Outros)
Cambridge English Language Assessment Spain and Portugal, Spain
Affiliation

Science

Category
Host institution 		Employer
2021/01/01 - Current Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2024/01/09 - 2024/04/10 Visiting Researcher (Research) Università degli Studi di Pavia Dipartimento di Chimica, Italy
2018/07/01 - 2018/08/01 Researcher (Research) OncoGen, Romania
2017/10/01 - 2018/06/01 Researcher (Research) Universidade de Coimbra Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
2019/09/01 - 2020/11/01 Researcher (Pharmaceutical Industry) Pranac, Portugal
2019/05/01 - 2019/08/16 Pharmacist Farmácia Machado, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/01/01 - 2019/04/01 Medical Affairs Trainee Bluepharma, Portugal
2017/07/01 - 2017/08/01 Pharmacist Farmácia Ygeia, Portugal
Projects

Grant

Designation Funders
2021/01/01 - 2024/12/31 Fine tuning circadian rhythm as an innovative approach against Machado-Joseph Disease
2020.04850.BD
10.54499/2020.04850.BD
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2024/01/09 - 2024/04/09 Development of novel Sirtuin-1 activators as new drug candidates to ameliorate Machado-Joseph Disease
10569
PhD Student Fellow
Università degli Studi di Pavia Dipartimento di Chimica, Italy
 EMBO (European Molecular Biology Organization)

Other

Designation Funders
2023/05/01 - Current NEURODIET - Mecanismos Moleculares de Intervenções Nutricionais na Neurodegenerescência (PT002)
JPND/0002/2022
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal
ERA-Net Cofund scheme
2023/01/15 - Current ARDAT: Accelerating R&D for Advanced Therapies
945473
PhD Student Fellow
Innovative Medicines Initiative
2022/01/17 - 2023/04/17 Reset - Resveratrol as Therapeutic Strategy in Machado-Joseph Disease.
RESET
PhD Student Fellow
Comissão de Coordenação e Desenvolvimento Regional do Centro
Outputs

Publications

Conference abstract
  1. Rodrigo F.N. Ribeiro; Dina Pereira; Tiago Reis; Sara Lopes; Marisa Ferreira-Marques; Rita Fernandes; Leatitia S Gaspar; et al. "Investigating the Clock Components and Circadian Activity in the YAC-MJD Mouse Model". Paper presented in SPF Meeting 2023 - Reunião da Sociedade Portuguesa de Farmacologia, Farmacologia Clínica e de Toxicologia, Coimbra, 2023.
  2. Ribeiro, Rodrigo; Carmo-Silva, Sara; Álvaro, Ana Rita ; Cavadas, Claudia; Silva, MMC. "Searching for New Circadian Rhythm Regulators to Delay Aging". Paper presented in iMed Conference® 10.0 (AstraZeneca Foundation Innovate Competition), Lisbon, 2018.
Conference poster
  1. Lobo, Diana Duarte; L Quintino; AC Silva ; C Henriques; Rodrigo F.N. Ribeiro; Sara M Lopes; P Perdigão; et al. "CRISPR activation as a therapeutic tool for Spinocerebellar ataxia type 3 (SCA3)". Paper presented in ESGCT meeting, 2023.
  2. Rodrigo F.N. Ribeiro; Dina Pereira; Tiago Reis; Sara Lopes; Marisa Ferreira-Marques; Rita Fernandes; Laetitia S Gaspar; et al. "The Circadian Clock is Disrupted in the YAC Machado-Joseph Disease Mouse Model". Paper presented in BEB Day 2023 - Doctoral Programme in Experimental Biology and Biomedicine (PDBEB) 17th symposium, 2023.
  3. Rodrigo F.N. Ribeiro; Silva, MMC. "Improving the synthetic pathways to access age-promoting agents - Chemical and biocatalytic synthesis of oxysterols". Paper presented in Ageing: models, mechanisms and therapies, 2019.
Journal article
  1. Rodrigo F.N. Ribeiro; Dina Pereira; Luis Pereira de Almeida; Maria Manuel C. Silva; Cláudia Cavadas. "SIRT1 activation and its circadian clock control: a promising approach against (frailty in) neurodegenerative disorders". Aging Clinical and Experimental Research (2022): https://doi.org/10.1007/s40520-022-02257-y.
    10.1007/s40520-022-02257-y
  2. Rodrigo F.N. Ribeiro; Cavadas, Cláudia; Silva, Maria Manuel C.. "Small-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases". Drug Discovery Today 26 7 (2021): 1620-1641. http://dx.doi.org/10.1016/j.drudis.2021.03.015.
    10.1016/j.drudis.2021.03.015
Thesis / Dissertation
  1. Ribeiro, Rodrigo. "Small Molecule Modulators of the Circadian Rhythm: From Identification & Development to Pharmacological Potentials in Clock-related Disorders". Master, Universidade de Coimbra Faculdade de Farmácia, 2019. http://hdl.handle.net/10316/88258.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/11/24 Alterations In The Molecular Components Of The Circadian Clock In A Mouse Model Of Neurodegeneration Pharma PhD Day - Annual Meeting of PhD Students in Pharmaceutical Sciences
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2023/04/27 Setting the (circadian) clock: An innovative strategy against neurodegenerative diseases PubhD Coimbra - "Three PhD students talk about science in a bar"
iiiUC (Instituto de Investigação Interdisciplinar) (Coimbra, Portugal)
2023/02/03 Investigating the Clock Components and Circadian Activity in the YAC-MJD Mouse Model SPF Meeting 2023 - Reunião da Sociedade Portuguesa de Farmacologia, Farmacologia Clínica e de Toxicologia
(Coimbra, Portugal)
2021/12/16 Fine tuning circadian rhythm as an innovative approach against neurodegenerative disorders EIT Health Ageing PhD School - Annual Retreat 2021
EIT Health PhD School
2021/09/30 Small-molecule modulators of the circadian clock targeting SIRT1 as an innovative strategy against neurodegenerative disorders PhD Review Presentation / Seminar II
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2019/09/12 Small Molecule Modulators of the Circadian Rhythm: From Identification & Development to Pharmacological Potentials in Clock-related Disorders Public examination for the conclusion of the Integrated Master's Degree in Pharmaceutical Sciences
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2018/10/03 Searching for New Circadian Rhythm Regulators to Delay Aging iMed Conference® 10.0 - AstraZeneca Foundation Innovate Competition
Associação de Estudantes da Nova Medical School (Lisboa, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018/04/01 - 2018/05/19 UC 2030 – "Uma perspetiva estudantil quanto ao futuro da UC" (UC General Council and AAC) (2018/05/18 - 2018/05/19)
Conference (Member of the Organising Committee)
 Universidade de Coimbra, Portugal
2018/03/01 - 2018/04/20 Staff Assistant at the World Health Summit Regional Meeting (Coimbra) (2018/04/19 - 2018/04/20)
Meeting (Member of the Organising Committee)
 Centro Hospitalar e Universitário de Coimbra EPE, Portugal

Universidade de Coimbra, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/09/29 - 2023/09/29 Hands-on activities at the "European Researchers Night" with the title "Tic-Tac... e a Longevidade no Laboratório"
Other
Universidade de Coimbra, Portugal
2021/12/21 - 2021/12/22 Participation in the "Computational Structural Biology Tools" workshop
Workshop
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

BioData.pt, Portugal
2020/06/01 - 2020/06/23 Student of the advanced course "Pharmacometrics" from Doctoral Program in Pharmaceutical Sciences and Drugs R&D (FFUC) - Final classification: 17 of 20.
Workshop
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/04/01 - 2020/06/01 Completion of the online specialization course "Medicinal Chemistry: The Molecular Basis of Drug Discovery" - Final classification: 102% of 105%.
Workshop
Davidson College, United States

Novartis Institutes for BioMedical Research Inc, United States
2020/04/07 - 2020/05/05 Student of the advanced course "New frontiers in drug development" from Doctoral Program in Pharmaceutical Sciences and Drugs R&D (FFUC)- Final classification: 18 of 20.
Workshop
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/01/20 - 2020/01/31 Student of the advanced course "Core Technologies @ CNC" from Doctoral Program in Experimental Biology and Biomedicine (PDBEB) - Final classification: 18 of 20.
Workshop
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/01/03 - 2019/01/09 Completion of training given by Novartis in "GCP Compliance Training for HCPs V2.0" (based on ICH E6 (R2) GCP Guidelines) - Certification in Good Clinical Practice.
Workshop
Novartis Farma SA, Portugal

Bluepharma, Portugal
2018/03/02 - 2018/03/04 Representative of the Coimbra Academic Association in ENDA: National Meeting of Associative Directorates
Meeting
Universidade da Beira Interior, Portugal
2017/11/27 - 2017/12/05 Participation in the pharmaceutical Digital Marketing Course.
Workshop
Magium Farma, Portugal

Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/11/17 - 2017/11/17 Participation in a Basic Life Support course ministered by Safetyforma with professional certification by INEM, SIGO and DGERT.
Workshop
2017/03/16 - 2017/04/16 Participation in Excel and R System training.
Workshop
Universidade de Coimbra Faculdade de Farmácia, Portugal

Association member

Society Organization name Role
2017/01/01 - 2019/01/01 Senate of the University of Coimbra Student representative of the Faculty of Pharmacy of the University of Coimbra
2017/03/01 - 2018/01/01 Pharmacy Students Union of Academic Association of Coimbra (NEF/AAC) Educational Policy and Social Action coordinator

Committee member

Activity description
Role 		Institution / Organization
2023/05/18 - Current EuroGCT Translator Network - translation of EuroGCT articles (portuguese) to help make sense of gene and cell therapy - from science in the lab to treatments for patients.
Advisor / Consultant
 The European Consortium for Communicating Gene and Cell Therapy Information (EuroGCT), United Kingdom

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/04/24 - 2020/04/24 Presentation entitled "SARS-CoV: Clinical trials for the development of new vaccines" by invitation of the course coordinator. Tecnologia de Produção de Vacinas e Adjuvantes (MICF) Universidade de Coimbra Faculdade de Farmácia, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2017/02/01 - 2017/02/01 Participant, as a Student with Management Functions in the evaluation and accreditation meeting of the courses of the Faculty of Pharmacy of the University of Coimbra by the Evaluation Commission A3ES (Agência de Avaliação e Acreditação do Ensino Superior).
Other
 Universidade de Coimbra Faculdade de Farmácia, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2017/01/01 - 2019/01/01 Coimbra University Press

Mentoring / Tutoring

Topic Student name
2023/11/14 - 2024/01/10 Hosting and planning the internship in the Neuroendocrinology and Aging Group (CNC-UC) Maria Petrica
2023/07/01 - 2023/12/31 Extracurricular internship "pyActigraphy as tool to compare circadian rhythms parameters obtained with different actigraphs" Cristiana Azevedo
2023/07/17 - 2023/07/21 Ciência Viva Summer Internships 2023 Catarina Anunciação e Diogo Rodrigues
2022/04/26 - 2022/10/19 Pharmaceutical Chemistry extracurricular internship "Desenho e previsão das características farmacocinéticas de ésteres de ácidos gordos com capacidade de atravessar a barreira hematoencefálica" Marlene Rodrigues
2022/06/27 - 2022/07/01 Ciência Viva Summer Internships 2022 Juliana Lopes
2021/02/26 - 2021/06/15 Pharmaceutical Chemistry extracurricular internship "Análise comparativa das estruturas, potências e características físico-químicas dos ativadores da sirtuina-1" José Oliveira
Distinctions

Award

2023 EMBO Scientific Exchange Grant
EMBO (European Molecular Biology Organization), Germany
2019 University of Coimbra Honours Board - 5% best students 2018/2019
Universidade de Coimbra, Portugal
2018 Best Oral Presentation in Basic Research entitled Searching for New Circadian Rhythm Regulators to Delay Aging - 1st place - iMed Conference® 10.0 (AstraZeneca Foundation Innovate Competition) held in Lisboa, Portugal