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Identification

Personal identification

Full name
Himanshu Sharma

Citation names

  • Sharma, Himanshu

Author identifiers

Ciência ID
9411-CB72-5D9E
ORCID iD
0000-0001-9518-4671

Addresses

  • Departamento Química (Ala Departamental) Lab 377 CryoEM@NOVA Faculdade de Ciências e Tecnologia - NOVA , 2829-516, Caparica, Caparica, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Infectious Diseases

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Hindi (Mother tongue)
Education
Degree Classification
2019/06/20
Concluded
 PhD (Doktor (PhD))
Major in Biosciences and Bioengineering
Indian Institute of Technology Guwahati, India
"Strategies and approaches for mechanistic understanding of bacterial ribosome assembly" (THESIS/DISSERTATION)
Affiliation

Positions / Appointments

Category
Host institution 		Employer
2025/05/01 - Current Manager of Laboratory, Institute, Museum, Centre or Observatory Universidade Nova de Lisboa, Portugal
Projects

Grant

Designation Funders
2021/10/01 - 2023/10/01 Mechanistic basis of host infection and intracellular development in microsporidia
101033469
Post-doc Fellow
European Commission Marie Sklodowska-Curie Actions, Belgium
 European Commission
Concluded
Outputs

Publications

Book chapter
  1. Ankita Punetha; Payel Sarkar; Siddharth Nimkar; Himanshu Sharma; Yoganand KNR; Siranjeevi Nagaraj. "Structural Bioinformatics: Life Through The 3D Glasses". 2018.
    10.1007/978-981-13-1562-6_10
Journal article
  1. Dario Valter Conca; Fouzia Bano; Malgorzata Graul; Julius von Wirén; Lauriane Scherrer; Hudson Pace; Himanshu Sharma; et al. "Variant-Specific Interactions at the Plasma Membrane: Heparan Sulfate’s Impact on SARS-CoV-2 Binding Kinetics". Analytical Chemistry (2025): http://dx.doi.org/10.1021/acs.analchem.4c04283.
    10.1021/acs.analchem.4c04283
  2. Kasturika Shankar; Marie N. Sorin; Himanshu Sharma; Oskar Skoglund; Selma Dahmane; Josy Ter Beek; Solomon Tesfalidet; Louise Nenzén; Lars-Anders Carlson. "In vitroreconstitution reveals membrane clustering and RNA recruitment by the enteroviral AAA+ ATPase 2C". PLOS Pathogens 20(8): e10 (2024): https://doi.org/10.1101/2023.10.11.561830.
    10.1101/2023.10.11.561830
  3. Sharma, Himanshu; Jespersen, Nathan; Ehrenbolger, Kai; Carlson, Lars-Anders; Barandun, Jonas. "Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion". PLOS Biology 22 2 (2024): e3002533. https://doi.org/10.1371/journal.pbio.3002533.
    Published • 10.1371/journal.pbio.3002533
  4. Svedberg, Dennis; Winiger, Rahel R.; Berg, Alexandra; Sharma, Himanshu; Tellgren-Roth, Christian; Debrunner-Vossbrinck, Bettina A.; Vossbrinck, Charles R.; Barandun, Jonas. "Functional annotation of a divergent genome using sequence and structure-based similarity". BMC Genomics 25 1 (2024): https://doi.org/10.1186/s12864-023-09924-y.
    10.1186/s12864-023-09924-y
  5. Ehrenbolger, Kai; Jespersen, Nathan; Sharma, Himanshu; Sokolova, Yuliya Y.; Tokarev, Yuri S.; Vossbrinck, Charles R.; Barandun, Jonas. "Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome". PLOS Biology 18 10 (2020): e3000958. https://doi.org/10.1371/journal.pbio.3000958.
    Open access • Published • 10.1371/journal.pbio.3000958
  6. Sharma, Himanshu. "Ribosome assembly defects subvert initiation Factor3 mediated scrutiny of bona fide start signal". Nucleic Acids Research 47 21 (2019): 11368-11386. http://dx.doi.org/10.1093/nar/gkz825.
    Open access • Published • 10.1093/nar/gkz825
  7. Sharma, Himanshu; Anand, Baskaran. "Fluorescence bimolecular complementation enables facile detection of ribosome assembly defects in Escherichia coli". RNA Biology 13 9 (2016): 872-882. https://doi.org/10.1080/15476286.2016.1207037.
    10.1080/15476286.2016.1207037

Other

Other output
  1. Assembly Defects Abrogate Proofreading by Initiation Factors and License the Entry of Premature Ribosomes into the Translation Cycle:. 2018. Sharma H; Anand B. http://europepmc.org/abstract/PPR/PPR65103.
    10.1101/498592