Identification
Personal identification
- Full name
- João Vasco Ferreira
Citation names
- Ferreira, João
- Ferreira JV
Author identifiers
- Ciência ID
- 931F-D94F-7E67
- ORCID iD
- 0000-0001-5897-7461
- Google Scholar ID
- https://scholar.google.com/citations?user=KE3Hh0kAAAAJ&hl=pt-PT
Knowledge fields
- Medical and Health Sciences - Basic Medicine
- Medical and Health Sciences - Basic Medicine
- Medical and Health Sciences - Basic Medicine
- Natural sciences - Biological Sciences - Cell Biology
- Natural sciences - Biological Sciences - Molecular Biology
- Medical and Health Sciences - Basic Medicine
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
Spanish; Castilian | Advanced (C1) | Advanced (C1) | Intermediate (B1) | Advanced (C1) | |
French | Elementary (A2) | Intermediate (B1) | Elementary (A2) | Elementary (A2) |
Education
Degree | Classification | |
---|---|---|
2023 - 2023
Concluded
|
Theoretical course in Laboratory Animal Sciences (20h). FELASA category: A. (Outros)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
|
|
2013
Concluded
|
Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
Albert Einstein College of Medicine, United States "HIF & CHIPs: a new autophagic pathway for the degradation of HIF-1alpha" (THESIS/DISSERTATION)
|
Aprovado por unanimidade com louvor e distinção |
2007
Concluded
|
Mestrado em Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"The relevance of the ubiquitin-proteasome pathway in the regulation of intercellular communication through gap junctions" (THESIS/DISSERTATION)
|
Classificação Máxima de Muito Bom |
2004
Concluded
|
Licenciatura em Biologia (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"n/a" (THESIS/DISSERTATION)
|
15 valores |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2023/06/01 - Current | Research Assistant (Research) | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2017/03/01 - 2023/06/01 | FCT PostDoc Grant holder ref: SFRH/BPD/121271/2016 | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2015/06/04 - 2017/02/04 | Investigador Contratado CONT_DOUT/19/UC/3282/14195/12/ | Universidade de Coimbra Faculdade de Medicina, Portugal |
2014/02/01 - 2014/08/31 | Research Grant holder of the project PTDC/SAU/ORG/113542/2009 | Universidade de Coimbra Faculdade de Medicina, Portugal |
2012/11/01 - 2013/07/31 | Research Grant holder of the project PTDC/SAU/ORG/113542/2009 | Universidade de Coimbra Faculdade de Medicina, Portugal |
2007/09/01 - 2011/09/01 | PhD Grant Holder | Universidade de Coimbra Faculdade de Medicina, Portugal |
2004/09/01 - 2007/04/23 | Master Student | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
2003/09/01 - 2004/09/01 | Trainee | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2023 - Current | Extracellular vesicles are critical players in the transcellular regulation of proteostasis in Age-related Macular Degeneration
2022.08649.PTDC
Researcher
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022 - Current | EVCA Twinning on Extracellular Vesicles
Researcher
|
Horizon 2020
Ongoing
|
2021 - Current | The Science of testing for COVID-19: Towards improved diagnostics and better health solutions. 300k
02/SAICT/2020-72552
Researcher
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2017 - Current | Re-acidification of lysosomes as a novel therapy for age-related retinal degeneration
Boehringer
Researcher
|
Boehringer Ingelheim AB |
2017 - Current | Engineered exosomes as new therapeutic tools to restore proteostasis in age-related degenerative diseases
LISBOA-01-0145- FEDER-007344
Researcher
|
Fundação para a Ciência e a Tecnologia |
2010/04/01 - Current | An animal model for age-related changes in proteostasis
Research Fellow
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2009/03/01 - Current | Tumorigenesis as a working model for the physiological role of HIF-1alpha degradation by chaperone-mediated autophagy
Research Fellow
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2006 - Current | A new route for endothelial dysfunction on diabetes: From phenotypes to molecules
PTDC/SAU-OSM/67498/2006
Researcher
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2019/01/01 - 2019/10/31 | iNOVA4Health - Programme in Translational Medicine (iBET, CEDOC/FCM, IPOLFG and ITQB)
UID/Multi/04462/2019
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal Universidade Nova de Lisboa, Portugal Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal Universidade Nova de Lisboa Medical School, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2012/04/01 - 2015/09/30 | Um modelo animal para o estudo de alterações de proteostase associadas ao envelhecimento
PTDC/SAU-ORG/118694/2010
Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2004 - 2008 | Filling in the GAP: the missing link between intercellular communication and diabetic retinopathy.
POCI/SAU-MMO/57216/2004
Universidade de Coimbra Faculdade de Medicina, Portugal
|
Universidade do Algarve Faculdade de Ciências e Tecnologia Fundação para a Ciência e a Tecnologia Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference paper |
|
Conference poster |
|
Journal article |
|
Journal issue |
|
Newspaper article |
|
Online resource |
|
Preprint |
|
Intellectual property
Patent |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2025/06 | Defining Exosomal Specificity: LAMP2A-Mediated Protein Loading and Its Impact on Endosomal Dynamics | 3rd meeting of The Portuguese Network on Extracellular vesicles
Universidade do Algarve (Faro, Portugal)
|
2024 | Optimizing CRISPR/Cas9 Delivery using Engineered Exosomes: Harnessing ExoSignal for Efficient Loading and Precise Gene Editing | EVCA Winter Retreat
EVCA Extracellular vesicles in diagnistics and disease (Sesimbra, Portugal)
|
2023 | Exploring the Versatile Role of LAMP2A: Insights into Exosomal Cargo Loading and Endosomal Identity in Inter-Cellular Communication | MOVE symposium 24-27th of October 2023
(Spain)
|
2023 | LAMP2A regulates the loading of proteins into exosomes. | 2nd meeting of the Portuguese Network on Extracellular Vesicles
(Portugal)
|
2022 | Loading of Proteins into Exosomes. | ESACT meeting 2022
(Portugal)
|
2022 | LAMP2A and Specific Peptide Motifs Regulate the Loading of Proteins into Exosomes | Extracellular Vesicles Gordon Research Conference 2022
(United States)
|
2019 | Ubiquitinylation of HIF1alpha regulates multiple degradation pathways and intercellular signaling. Invited | Druggability of the ubiquitin system - which road to take?
(Portugal)
|
2017 | Selective protein sorting into exosomes. | Opportunities for PostDoctoral Researchers in Life Sciences. |
2016 | STUB1-Ataxin3 editing machine for the degradation of HIF1A by Chaperone-Mediated Autophagy. | 3rd PROTEOSTASIS Action Meeting
COST (Lisboa)
|
2016 | STUB1-Ataxin3 editing machine for the degradation of HIF1A by Chaperone-Mediated Autophagy. | 3rd PROTEOSTASIS COST Action Meeting |
2013 | Lys63 ubiquitin chains in hypoxia: the degradation of HIF1A by Chaperone-Mediated Autophagy - | SINAL meeting, University of Coimbra, Coimbra, Portugal. |
2012 | Starvation induces CMA-dependent degradation of HIF-1a | IBILI Meeting |
2012 | Starvation induces CMA-dependent degradation of HIF-1a | 2nd PF2MUC Meetin |
2007 | Crosstalk between chaperone-mediated autophagy and the ubiquitin-proteassome pathway in the degradation of oxidized proteins induced by 7k: implications in AMD. | 2007 EMBO conference and FEBS Workshop on "Chaperones in Normal & Aberrant Protein Folding, Aging & Cancer" from June 9th - 14th, 2007 |
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2022 - Current | Role of exosomes in the COVID-19 disease
Supervisor
|
Biomedical research (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022 - Current | Exosomes as vehicles of intercellular hypoxia signaling in bone epimorphic regeneration.
Supervisor
|
Biomedical research (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022 - Current | Transcellular regulation of proteostasis in Age-related Macular Degeneration
Supervisor
|
Biomedical research (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022 - 2023 | NBR master
Supervisor
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022 - 2023 | NBR master
Supervisor
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022 - 2023 | NBR master
Supervisor
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2018 - 2023 | Exosome engineering - A new therapeutic toll for age-related macular degeneration
Supervisor of Catarina Máximo Carvalho
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022/02 - 2022/04 | Exosomes in transcellular proteostasis and Age-Related Macular Degeneration
Supervisor
|
Biomedical Research (Scientific initiation)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
2018 - 2019 | NBR master
Supervisor
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2015 - 2019 | A new mechanism for selective protein loading into exosomes
Supervisor of Ana Rosa Soares
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2010 - 2010 | Integrated masters in Medicine
Co-supervisor
|
Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2023 - 2023 | Extracellular Vesicles: Molecular and functional characterization applying OMICS technologies combined with Bioinformatics
tools (2023 - 2023)
Workshop (Member of the Scientific Committee)
|
|
2022 - 2022 | Organized the workshop “EXTRACELLULAR VESICLES – FROM BASIC BIOLOGY TO PRODUCTION OF EVs AS NOVEL THERAPEUTICS” at ESACT meeting
2022. (https://esact2022.com/index.php/programme/pre-conference-workshops-and-symposia) (2022 - 2022)
Workshop (Co-organisor)
|
|
2018 - 2018 | Second NMS Symposium on Chronic Diseases 2018 (http://cedoc.unl.pt/symposium-2018/) (2018 - 2018)
Conference (Member of the Organising Committee)
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2016 - 2016 | First CEDOC Symposium on Chronic Diseases 2016 (http://cedoc.unl.pt/symposium2016/) (2016 - 2016)
Conference (Member of the Organising Committee)
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2017 - Current | NOVA Medical School Research (NMSR) Open day
Other
|
|
2017 - Current | Nova Medical School (NMS) Open day
Other
|
|
2017 - Current | Ciência Viva Program | |
2017 - Current | Open day and the European Researchers Night |
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2023 | The mechanism of LAMP2A-mediated exosome biogenesis and their role in intercellular communication
Supervisor
|
Catarina Máximo (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2023 | EXOSOMES IN TRANSCELLULAR PROTEOSTASIS AND AGE RELATED MACULAR DEGENERATION
Supervisor
|
Luís Ferraz (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
Committee member
Activity description Role |
Institution / Organization | |
---|---|---|
2023 - Current | Committee member of the EU Twinning Project (1500K) in extracellular vesicles in diagnostic and therapy
Member
|
iNOVA4Health, Portugal Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2017 - 2018 | Member of the PosDoc Committee at CEDOC
Member
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2015 - 2016 | Member of the PosDoc Committee at CEDOC
Member
|
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2009 - 2011 | Member of the General Assembly of the Faculty of Medicine, University of Coimbra
Member
|
Universidade de Coimbra Faculdade de Medicina, Portugal |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2022 - Current | The biomedical research training course (university extension) – B, at CEDOC FCM|NMS is intended for undergraduates (1st cycle), Masters (2nd cycle), PhD holders or equivalent European degrees, who aim to further develop their research working skills, included in a research project with the aim of obtaining a diploma. | Biomedical research training course (university extension) (Pós-Graduação) | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2022 - Current | Investigação | Medicina (Mestrado integrado) | Universidade Nova de Lisboa, Portugal |
2017 - Current | NBR (NOVA Biomedical Research)- Advanced courses and Lab rotations | (Curso de mestrado (conclusão do curso de especialização)) | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2017 - Current | NOVA Medical School PhD Programme advanced courses | (Curso de doutoramento (conclusão de unidades curriculares)) | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2017 - Current | Integrated masters in Medicine of NOVA Medical School | Integrated master in Medicine (Mestrado integrado) | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
2009 - 2015 | Master in Biomedical Research-Advanced courses and Lab Rotations | (Mestrado) | Universidade de Coimbra Faculdade de Medicina, Portugal |
2009 - 2015 | PHDESC (Inter-University Doctoral Programme in Ageing and Chronic Disease)- Advanced Courses and Lab Rotations | (Curso de doutoramento (conclusão de unidades curriculares)) | Universidade de Coimbra Faculdade de Medicina, Portugal |
2009 - 2015 | PHDHS (Doctoral Programme in Health Sciences)- Advanced Courses and Lab Rotations | (Curso de doutoramento (conclusão de unidades curriculares)) | Universidade de Coimbra Faculdade de Medicina, Portugal |
2009 - 2015 | MBCM (Masters in Cell and MoleculAr Biology)- Advanced Courses | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
Interview (newspaper / magazine)
Activity description | Newspaper / Forum | |
---|---|---|
2023 | International Extracellular Vesicle Club. LAMP2A regulates the loading of proteins into exosomes. https://www.youtube.com/watch?v=sguYoh3G1pY&t=115s | youtube |
2022/04/17 | First page and article with interview, with the title: Desvendado um dos segredos das "cartas" que as nossas células recebem. / Unraveled one of the mysteries regarding the "letters" cells receive. | Publico.pt |
Other jury / evaluation
Activity description | Institution / Organization | |
---|---|---|
2022 - Current | Grant reviewer for the National Science Center in Poland | |
2016 - 2016 | Member of the Juri for the award of the FMUC-Santander Totta research grants | Universidade de Coimbra Faculdade de Medicina, Portugal |
Distinctions
Award
2023 | Best Presentation |
Other distinction
2023 | Assitant Researcher contract
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2022 | Decoration Medal for Outstanding Achievement |
2016 | PostDoc Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|
2015 | Assitant researcher contract
Universidade de Coimbra Faculdade de Medicina, Portugal
|
2007 | PhD Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|
2006 | Best poster in the retina/vitreous session |