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Identification

Personal identification

Full name
João António de Sampaio Rodrigues Queiroz

Citation names

  • Queiroz, João
  • Queiroz, J.A.

Author identifiers

Ciência ID
931E-B66D-E341
ORCID iD
0000-0002-3096-8325

Email addresses

  • jqueiroz@ubi.pt (Professional)

Addresses

  • Universidade da Beira Interior, 6201-001, Covilhã, Covilhã, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemical Research Methods
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
Education
Degree Classification
2002
Concluded
 Bioquímica (Título de Agregado)
Universidade da Beira Interior, Portugal
1991 - 1996
Concluded
 Química (Doutoramento)
Universidade da Beira Interior, Portugal
1988 - 1991
Concluded
 Biotecnologia (Engenharia Bioquímica) (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
1982 - 1986
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2003 - Current Full Professor (University Teacher) Universidade da Beira Interior, Portugal
2000 - 2003 Associate Professor (University Teacher) Universidade da Beira Interior, Portugal
1996 - 2000 Assistant Professor (University Teacher) Universidade da Beira Interior, Portugal
1991 - 1996 Assistant (University Teacher) Universidade da Beira Interior, Portugal
1986 - 1991 Trainee Assistant (University Teacher) Universidade da Beira Interior, Portugal
Outputs

Publications

Book
  1. Gaspar, V.M.; Moreira, A.F.; de Melo-Diogo, D.; Costa, E.C.; Queiroz, J.A.; Sousa, F.; Pichon, C.; Correia, I.J.. Multifunctional nanocarriers for codelivery of nucleic acids and chemotherapeutics to cancer cells. 2016.
    10.1016/B978-0-323-41736-5.00006-6
  2. Costa, D.; Valente, A.J.M.; Queiroz, J.. Responsive Plasmid DNA Hydrogels: A New Approach for Biomedical Applications. 2015.
    10.1002/9781119041559.ch6
  3. Sousa, Â.; Queiroz, J.A.; Sousa, F.. p53-encoding pDNA purification by affinity chromatography for cancer therapy. 2015.
    10.1007/978-1-4939-2727-2_7
  4. Gomes, A.P.; Mano, J.F.; Queiroz, J.A.; Gouveia, I.C.. Layer-by-layer assembly for biofunctionalization of cellulosic fibers with emergent antimicrobial agents. 2015.
    10.1007/12_2015_318
  5. Tomaz, C.T.; Queiroz, J.A.. Hydrophobic Interaction Chromatography. 2013.
    10.1016/B978-0-12-415807-8.00006-7
Book chapter
  1. Carapito, R.; Valente, J.F.A.; Queiroz, J.A.; Sousa, F.. "Arginine-Affinity Chromatography for Nucleic Acid (DNA and RNA) Isolation". 135-144. 2022.
    10.1007/978-1-0716-2176-9_10
  2. Almeida, A.M.; Eusébio, D.; Queiroz, J.A.; Sousa, F.; Sousa, Â.. "Minicircle DNA Vaccine Purification and E7 Antigen Expression Assessment". 207-222. 2021.
    10.1007/978-1-0716-0872-2_11
  3. Costa, D.; Sousa, Â.; Faria, R.; Neves, A.R.; Queiroz, J.A.. "Conception of Plasmid DNA and Polyethylenimine Delivery Systems with Potential Application in DNA Vaccines Field". 271-284. 2021.
    10.1007/978-1-0716-0872-2_15
Journal article
  1. Ana M. Gonçalves; Augusto Q. Pedro; Diana M. Oliveira; Adriana E. Oliveira; Marino F. A. Santos; Márcia A. S. Correia; João A. Queiroz; et al. "Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232012298.
    10.3390/ijms232012298
  2. Sousa, Â.; Almeida, A.M.; Valente, J.; Queiroz, J.; Sousa, F.. "Hands-On Laboratory Class for Biopharmaceutical pDNA Quality Control". Journal of Chemical Education 99 2 (2022): 975-982. http://www.scopus.com/inward/record.url?eid=2-s2.0-85123923683&partnerID=MN8TOARS.
    10.1021/acs.jchemed.1c00695
  3. Gonçalves, A.M.; Sousa, Â.; Pedro, A.Q.; Romão, M.J.; Queiroz, J.A.; Gallardo, E.; Passarinha, L.A.. "Advances in Membrane-Bound Catechol-O-Methyltransferase Stability Achieved Using a New Ionic Liquid-Based Storage Formulation". International Journal of Molecular Sciences 23 13 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85133120009&partnerID=MN8TOARS.
    10.3390/ijms23137264
  4. Cruz-Vicente, P.; Gonçalves, A.M.; Barroca-Ferreira, J.; Silvestre, S.M.; Romão, M.J.; Queiroz, J.A.; Gallardo, E.; Passarinha, L.A.. "Unveiling the biopathway for the design of novel COMT inhibitors". Drug Discovery Today 27 10 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85135397812&partnerID=MN8TOARS.
    10.1016/j.drudis.2022.07.013
  5. Pedro Cruz-Vicente; Ana M. Gonçalves; Octávio Ferreira; João A. Queiroz; Samuel Silvestre; Luís A. Passarinha; Eugenia Gallardo. "Discovery of Small Molecules as Membrane-Bound Catechol-O-methyltransferase Inhibitors with Interest in Parkinson’s Disease: Pharmacophore Modeling, Molecular Docking and In Vitro Experimental Validation Studies". Pharmaceuticals 15 1 (2021): 51-51. https://doi.org/10.3390/ph15010051.
    10.3390/ph15010051
  6. B. Baptista; M. Riscado; J.A. Queiroz; C. Pichon; F. Sousa. "Non-coding RNAs: Emerging from the discovery to therapeutic applications". Biochemical Pharmacology (2021): 114469-114469. https://doi.org/10.1016/j.bcp.2021.114469.
    10.1016/j.bcp.2021.114469
  7. Valente, J.F.A.; Queiroz, J.A.; Sousa, F.. "Dilemma on plasmid DNA purification: binding capacity vs selectivity". Journal of Chromatography A 1637 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85098940390&partnerID=MN8TOARS.
    10.1016/j.chroma.2020.461848
  8. Eusébio, D.; Almeida, A.M.; Alves, J.M.; Maia, C.J.; Queiroz, J.A.; Sousa, F.; Sousa, Â.. "The Performance of Minicircle DNA Versus Parental Plasmid in p53 Gene Delivery into HPV-18-Infected Cervical Cancer Cells". Nucleic Acid Therapeutics 31 1 (2021): 82-91. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100970797&partnerID=MN8TOARS.
    10.1089/nat.2020.0904
  9. Carvalho, J.; Lopes-Nunes, J.; Campello, M.P.C.; Paulo, A.; Milici, J.; Meyers, C.; Mergny, J.-L.; et al. "Human Papillomavirus G-Rich Regions as Potential Antiviral Drug Targets". Nucleic Acid Therapeutics 31 1 (2021): 68-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100988111&partnerID=MN8TOARS.
    10.1089/nat.2020.0869
  10. Gomes, D.; Gonçalves, C.; Gonçalves, A.M.; Queiroz, J.A.; Sousa, A.; Passarinha, L.A.. "Applications of gellan natural polymer microspheres in recombinant catechol-O-methyltransferase direct capture from a Komagataella pastoris lysate". International journal of biological macromolecules 172 (2021): 186-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-85102213173&partnerID=MN8TOARS.
    10.1016/j.ijbiomac.2020.12.225
  11. Gomes, D.; Costa, D.; Queiroz, J.A.; Passarinha, L.A.; Sousa, A.. "A new insight in gellan microspheres application to capture a plasmid DNA vaccine from an Escherichia coli lysate". Separation and Purification Technology 274 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85106603209&partnerID=MN8TOARS.
    10.1016/j.seppur.2021.119013
  12. Carvalho, J.; Lopes-Nunes, J.; Vialet, B.; Rosado, T.; Gallardo, E.; Vale, J.; Eloy, C.; et al. "Nanoaggregate-forming lipid-conjugated AS1411 aptamer as a promising tumor-targeted delivery system of anticancer agents in vitro". Nanomedicine: Nanotechnology, Biology, and Medicine 36 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85109880646&partnerID=MN8TOARS.
    10.1016/j.nano.2021.102429
  13. Valente, J.F.A.; Pereira, P.; Sousa, A.; Queiroz, J.A.; Sousa, F.. "Effect of plasmid DNA size on chitosan or polyethyleneimine polyplexes formulation". Polymers 13 5 (2021): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-85102862704&partnerID=MN8TOARS.
    10.3390/polym13050793
  14. Patrícia Pereira; Maria Barreira; Carla Cruz; Joana Tomás; Ângelo Luís; Augusto Q. Pedro; João A. Queiroz; Fani Sousa. "Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes". Pharmaceuticals 13 10 (2020): 314-314. https://doi.org/10.3390/ph13100314.
    10.3390/ph13100314
  15. Ana Margarida Almeida; João António Queiroz; Fani Sousa; Ângela Sousa. "Minicircle DNA: The Future for DNA-Based Vectors?". Trends in Biotechnology (2020): https://doi.org/10.1016/j.tibtech.2020.04.008.
    10.1016/j.tibtech.2020.04.008
  16. J.F.A. Valente; A. Sousa; G.A. Azevedo; J.A. Queiroz; F. Sousa. "Purification of supercoiled p53-encoding plasmid using an arginine-modified macroporous support". Journal of Chromatography A 1618 (2020): 460890-460890. https://doi.org/10.1016/j.chroma.2020.460890.
    10.1016/j.chroma.2020.460890
  17. A.M. Almeida; D. Eusébio; J.A. Queiroz; F. Sousa; A. Sousa. "The use of size-exclusion chromatography in the isolation of supercoiled minicircle DNA from Escherichia coli lysate". Journal of Chromatography A 1609 (2020): 460444-460444. https://doi.org/10.1016/j.chroma.2019.460444.
    10.1016/j.chroma.2019.460444
  18. Neves, A.R.; Sousa, A.; Faria, R.; Albuquerque, T.; Queiroz, J.A.; Costa, D.. "Cancer gene therapy mediated by RALA/plasmid DNA vectors: Nitrogen to phosphate groups ratio (N/P) as a tool for tunable transfection efficiency and apoptosis". Colloids and Surfaces B: Biointerfaces 185 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85075403667&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2019.110610
  19. Almeida, A.M.; Cernigoj, U.; Queiroz, J.A.; Sousa, F.; Sousa, A.. "Quality assessment of supercoiled minicircle DNA by cadaverine-modified analytical chromatographic monolith". Journal of Pharmaceutical and Biomedical Analysis 180 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076629062&partnerID=MN8TOARS.
    10.1016/j.jpba.2019.113037
  20. Carvalho, J.; Santos, T.; Carrilho, R.; Sousa, F.; Salgado, G.F.; Queiroz, J.A.; Cruz, C.. "Ligand screening to pre-miRNA 149 G-quadruplex investigated by molecular dynamics". Journal of Biomolecular Structure and Dynamics 38 8 (2020): 2276-2286. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068552561&partnerID=MN8TOARS.
    10.1080/07391102.2019.1632743
  21. Almeida, A.M.; Costa, D.; Simões, A.R.; Queiroz, J.A.; Sousa, F.; Sousa, Â.. "Enhancement of a biotechnological platform for the purification and delivery of a human papillomavirus supercoiled plasmid DNA vaccine". New Biotechnology 59 (2020): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087506840&partnerID=MN8TOARS.
    10.1016/j.nbt.2020.04.003
  22. Neves, M.C.; Pereira, P.; Pedro, A.Q.; Martins, J.C.; Trindade, T.; Queiroz, J.A.; Freire, M.G.; Sousa, F.. "Improved ionic-liquid-functionalized macroporous supports able to purify nucleic acids in one step". Materials Today Bio 8 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85097649442&partnerID=MN8TOARS.
    10.1016/j.mtbio.2020.100086
  23. Cruz, C.; Pedro, A.Q.; Carvalho, J.; Santos, T.; Talhada, D.; Paiva, A.; Queiroz, J.A.; et al. "Nucleolin as a potential biomarker for canine malignant neoplasia". Research in Veterinary Science (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85092891530&partnerID=MN8TOARS.
    10.1016/j.rvsc.2020.10.004
  24. Albuquerque, T.; Faria, R.; Sousa, Â.; Neves, A.R.; Queiroz, J.A.; Costa, D.. "Polymer-peptide ternary systems as a tool to improve the properties of plasmid DNA vectors in gene delivery". Journal of Molecular Liquids 309 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85083723012&partnerID=MN8TOARS.
    10.1016/j.molliq.2020.113157
  25. Carvalho, J.; Mergny, J.-L.; Salgado, G.F.; Queiroz, J.A.; Cruz, C.. "G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies". Trends in Molecular Medicine 26 9 (2020): 848-861. http://www.scopus.com/inward/record.url?eid=2-s2.0-85085353394&partnerID=MN8TOARS.
    10.1016/j.molmed.2020.05.002
  26. Cristóvão, A.C.; Campos, F.L.; Je, G.; Esteves, M.; Guhathakurta, S.; Yang, L.; Beal, M.F.; et al. "Characterization of a Parkinson’s disease rat model using an upgraded paraquat exposure paradigm". European Journal of Neuroscience 52 4 (2020): 3242-3255. http://www.scopus.com/inward/record.url?eid=2-s2.0-85078945954&partnerID=MN8TOARS.
    10.1111/ejn.14683
  27. Sousa, Â.; Faria, R.; Albuquerque, T.; Bhatt, H.; Biswas, S.; Queiroz, J.A.; Costa, D.. "Design of experiments to select triphenylphosphonium-polyplexes with suitable physicochemical properties for mitochondrial gene therapy". Journal of Molecular Liquids 302 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078098670&partnerID=MN8TOARS.
    10.1016/j.molliq.2020.112488
  28. Lopes-Nunes, J.; Carvalho, J.; Figueiredo, J.; Ramos, C.I.V.; Lourenço, L.M.O.; Tomé, J.P.C.; Neves, M.G.P.M.S.; et al. "Phthalocyanines for G-quadruplex aptamers binding". Bioorganic Chemistry 100 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85084387066&partnerID=MN8TOARS.
    10.1016/j.bioorg.2020.103920
  29. G.M. Azevedo; J.F.A. Valente; A. Sousa; A.Q. Pedro; P. Pereira; F. Sousa; J.A. Queiroz. "Effect of Chromatographic Conditions on Supercoiled Plasmid DNA Stability and Bioactivity". Applied Sciences (2019): https://doi.org/10.3390/app9235170.
    10.3390/app9235170
  30. Maria V. Quental; Augusto Q. Pedro; Patrícia Pereira; Mukesh Sharma; João A. Queiroz; João A. P. Coutinho; Fani Sousa; Mara G. Freire. "Integrated Extraction-Preservation Strategies for RNA Using Biobased Ionic Liquids". ACS Sustainable Chemistry & Engineering (2019): https://doi.org/10.1021/acssuschemeng.9b00688.
    10.1021/acssuschemeng.9b00688
  31. Santos, T.; Pereira, P.; Campello, M.P.C.; Paulo, A.; Queiroz, J.A.; Cabrita, E.; Cruz, C.. "RNA G-quadruplex as supramolecular carrier for cancer-selective delivery". European Journal of Pharmaceutics and Biopharmaceutics 142 (2019): 473-479. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069644468&partnerID=MN8TOARS.
    10.1016/j.ejpb.2019.07.017
  32. Pedro, A.Q.; Queiroz, J.A.; Passarinha, L.A.. "Smoothing membrane protein structure determination by initial upstream stage improvements". Applied Microbiology and Biotechnology 103 14 (2019): 5483-5500. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067671986&partnerID=MN8TOARS.
    10.1007/s00253-019-09873-1
  33. Almeida, A.M.; Queiroz, J.A.; Sousa, F.; Sousa, Â.. "Cervical cancer and HPV infection: ongoing therapeutic research to counteract the action of E6 and E7 oncoproteins". Drug Discovery Today 24 10 (2019): 2044-2057. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070489597&partnerID=MN8TOARS.
    10.1016/j.drudis.2019.07.011
  34. Carvalho, J.; Paiva, A.; Cabral Campello, M.P.; Paulo, A.; Mergny, J.-L.; Salgado, G.F.; Queiroz, J.A.; Cruz, C.. "Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells". Scientific Reports 9 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067304166&partnerID=MN8TOARS.
    10.1038/s41598-019-44388-9
  35. Sousa, Â.; Almeida, A.M.; Faria, R.; Konate, K.; Boisguerin, P.; Queiroz, J.A.; Costa, D.. "Optimization of peptide-plasmid DNA vectors formulation for gene delivery in cancer therapy exploring design of experiments". Colloids and Surfaces B: Biointerfaces 183 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070406773&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2019.110417
  36. Carvalho, J.; Alves, S.; Castro, M.M.C.A.; Geraldes, C.F.G.C.; Queiroz, J.A.; Fonseca, C.P.; Cruz, C.. "Development of a bioreactor system for cytotoxic evaluation of pharmacological compounds in living cells using NMR spectroscopy". Journal of Pharmacological and Toxicological Methods 95 (2019): 70-78. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057852571&partnerID=MN8TOARS.
    10.1016/j.vascn.2018.11.004
  37. Faria, R.; Sousa, Â.; Neves, A.R.; Queiroz, J.A.; Costa, D.. "Methotrexate-plasmid DNA polyplexes for cancer therapy: Characterization, cancer cell targeting ability and tuned in vitro transfection". Journal of Molecular Liquids 292 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069657438&partnerID=MN8TOARS.
    10.1016/j.molliq.2019.111391
  38. Santos, T.; Pereira, P.; Queiroz, J.A.; Cruz, C.; Sousa, F.. "Plasmid production and purification: An integrated experiment-based biochemistry and biotechnology laboratory course". Biochemistry and Molecular Biology Education 47 6 (2019): 638-643. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070506483&partnerID=MN8TOARS.
    10.1002/bmb.21290
  39. Costa, D.; Albuquerque, T.; Queiroz, J.A.; Valente, A.J.M.. "A co-delivery platform based on plasmid DNA peptide-surfactant complexes: formation, characterization and release behavior". Colloids and Surfaces B: Biointerfaces 178 (2019): 430-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063215488&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2019.03.029
  40. Carvalho, J.; Lopes-Nunes, J.; Lopes, A.C.; Cabral Campello, M.P.; Paulo, A.; Queiroz, J.A.; Cruz, C.. "Aptamer-guided acridine derivatives for cervical cancer". Organic and Biomolecular Chemistry 17 11 (2019): 2992-3002. http://www.scopus.com/inward/record.url?eid=2-s2.0-85062851661&partnerID=MN8TOARS.
    10.1039/c9ob00318e
  41. Figueiredo, J.; Lopes-Nunes, J.; Carvalho, J.; Antunes, F.; Ribeiro, M.; Campello, M.P.C.; Paulo, A.; et al. "AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells". International Journal of Pharmaceutics 568 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85068927748&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2019.118511
  42. Almeida, A.M.; Queiroz, J.A.; Sousa, F.; Sousa, A.. "Minicircle DNA purification: Performance of chromatographic monoliths bearing lysine and cadaverine ligands". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1118-1119 (2019): 7-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-85064324749&partnerID=MN8TOARS.
    10.1016/j.jchromb.2019.04.024
  43. Valente, J.F.A.; Sousa, A.; Queiroz, J.A.; Sousa, F.. "DoE to improve supercoiled p53-pDNA purification by O-phospho-L-tyrosine chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1105 (2019): 184-192. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059140598&partnerID=MN8TOARS.
    10.1016/j.jchromb.2018.12.002
  44. Josué Carvalho; Jéssica Lopes-Nunes; Ana Catarina Lopes; Maria Paula Cabral Campello; António Paulo; João A. Queiroz; Carla Cruz. "Aptamer-guided acridine derivatives for cervical cancer". Organic & Biomolecular Chemistry (2019): https://doi.org/10.1039/C9OB00318E.
    10.1039/C9OB00318E
  45. Augusto Q. Pedro; Patrícia Pereira; Maria J. Quental; André P. Carvalho; Sérgio M. Santos; João A. Queiroz; Fani Sousa; Mara G. Freire. "Cholinium-Based Good’s Buffers Ionic Liquids as Remarkable Stabilizers and Recyclable Preservation Media for Recombinant Small RNAs". ACS Sustainable Chemistry & Engineering (2018): https://doi.org/10.1021/acssuschemeng.8b03900.
    10.1021/acssuschemeng.8b03900
  46. J.F.A. Valente; A. Sousa; V.M. Gaspar; J.A. Queiroz; F. Sousa. "The biological performance of purified supercoiled p53 plasmid DNA in different cancer cell lines". Process Biochemistry 75 (2018): 240-249. https://doi.org/10.1016/j.procbio.2018.09.014.
    10.1016/j.procbio.2018.09.014
  47. Carvalho, J.; Pereira, E.; Marquevielle, J.; Campello, M.P.C.; Mergny, J.-L.; Paulo, A.; Salgado, G.F.; Queiroz, J.A.; Cruz, C.. "Fluorescent light-up acridine orange derivatives bind and stabilize KRAS-22RT G-quadruplex". Biochimie 144 (2018): 144-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034062413&partnerID=MN8TOARS.
    10.1016/j.biochi.2017.11.004
  48. Josué Carvalho; Telma Quintela; Nassima M. Gueddouda; Anne Bourdoncle; Jean-Louis Mergny; Gilmar F. Salgado; João A. Queiroz; Carla Cruz. "Phenanthroline polyazamacrocycles as G-quadruplex DNA binders". Organic & Biomolecular Chemistry (2018): https://doi.org/10.1039/C8OB00247A.
    10.1039/C8OB00247A
  49. Almeida, A.M.; Tomás, J.; Pereira, P.; Queiroz, J.A.; Sousa, F.; Sousa, A.. "HPV-16 targeted DNA vaccine expression: The role of purification". Biotechnology Progress (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040709703&partnerID=MN8TOARS.
    10.1002/btpr.2603
  50. Pedro, A.Q.; Gonçalves, A.M.; Queiroz, J.A.; Passarinha, L.A.. "Purification of Histidine-Tagged Membrane-Bound Catechol-O-Methyltransferase from Detergent-Solubilized Pichia pastoris Membranes". Chromatographia 81 3 (2018): 425-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040066592&partnerID=MN8TOARS.
    10.1007/s10337-017-3453-5
  51. Valente, J.F.A.; Queiroz, J.A.; Sousa, F.. "P53 as the focus of gene therapy: Past, present and future". Current Drug Targets 19 15 (2018): 1801-1817. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052075362&partnerID=MN8TOARS.
    10.2174/1389450119666180115165447
  52. Carvalho, J.; Quintela, T.; Gueddouda, N.M.; Bourdoncle, A.; Mergny, J.-L.; Salgado, G.F.; Queiroz, J.A.; Cruz, C.. "Phenanthroline polyazamacrocycles as G-quadruplex DNA binders". Organic and Biomolecular Chemistry 16 15 (2018): 2776-2786. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045840880&partnerID=MN8TOARS.
    10.1039/c8ob00247a
  53. Cardoso, S.; Sousa, Â.; Queiroz, J.A.; Azzoni, A.R.; Sousa, F.. "Arginine homopeptides for plasmid DNA purification using monolithic supports". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1087-1088 (2018): 149-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046703207&partnerID=MN8TOARS.
    10.1016/j.jchromb.2018.04.031
  54. Gaspar, C.; Donders, G.G.; Palmeira-de-Oliveira, R.; Queiroz, J.A.; Tomaz, C.; Martinez-de-Oliveira, J.; Palmeira-de-Oliveira, A.. "Bacteriocin production of the probiotic Lactobacillus acidophilus KS400". AMB Express 8 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053932740&partnerID=MN8TOARS.
    10.1186/s13568-018-0679-z
  55. Costa, D.; Valente, A.J.M.; Queiroz, J.A.; Sousa, Â.. "Finding the ideal polyethylenimine-plasmid DNA system for co-delivery of payloads in cancer therapy". Colloids and Surfaces B: Biointerfaces 170 (2018): 627-636. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049322981&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2018.06.063
  56. Josué Carvalho; João A. Queiroz; Carla Cruz. "Circular Dichroism of G-Quadruplex: a Laboratory Experiment for the Study of Topology and Ligand Binding". Journal of Chemical Education 94 10 (2017): 1547-1551. https://doi.org/10.1021/acs.jchemed.7b00160.
    10.1021/acs.jchemed.7b00160
  57. Diana Costa; Carolina Costa; Margarida Caldeira; Luísa Cortes; João A. Queiroz; Carla Cruz. "Targeting of Cellular Organelles by Fluorescent Plasmid DNA Nanoparticles". Biomacromolecules 18 9 (2017): 2928-2936. https://doi.org/10.1021/acs.biomac.7b00877.
    10.1021/acs.biomac.7b00877
  58. T. Santos; Z. Proença; J.A. Queiroz; C. Tomaz; C. Cruz. "Plasmid purification by using a new naphthalene tripodal support". Separation and Purification Technology (2017):
    10.1016/j.seppur.2017.06.072
  59. Josué Carvalho; Pierre Nottelet; Jean-Louis Mergny; João A. Queiroz; Gilmar F. Salgado; Carla Cruz. "Study of the interaction between indole-based compounds and biologically relevant G-quadruplexes". Biochimie 135 (2017): 186-195. https://doi.org/10.1016/j.biochi.2017.02.005.
    10.1016/j.biochi.2017.02.005
  60. Pereira, P.; Queiroz, J.A.; Figueiras, A.; Sousa, F.. "Current progress on microRNAs-based therapeutics in neurodegenerative diseases". Wiley Interdisciplinary Reviews: RNA 8 3 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85006070818&partnerID=MN8TOARS.
    10.1002/wrna.1409
  61. Ferreira, J.; Santos, T.; Pereira, P.; Corvo, M.C.; Queiroz, J.A.; Sousa, F.; Cruz, C.. "Naphthalene amine support for G-quadruplex isolation". Analyst 142 16 (2017): 2982-2994. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027046702&partnerID=MN8TOARS.
    10.1039/c7an00648a
  62. Pereira, P.; Barreira, M.; Queiroz, J.A.; Veiga, F.; Sousa, F.; Figueiras, A.. "Smart micelleplexes as a new therapeutic approach for RNA delivery". Expert Opinion on Drug Delivery 14 3 (2017): 353-371. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013670117&partnerID=MN8TOARS.
    10.1080/17425247.2016.1214567
  63. Medeiros-Silva, J.; Guédin, A.; Salgado, G.F.; Mergny, J.-L.; Queiroz, J.A.; Cabrita, E.J.; Cruz, C.. "Phenanthroline-bis-oxazole ligands for binding and stabilization of G-quadruplexes". Biochimica et Biophysica Acta - General Subjects 1861 5 (2017): 1281-1292. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007330676&partnerID=MN8TOARS.
    10.1016/j.bbagen.2016.11.024
  64. Amorim, L.F.A.; Gaspar, R.; Pereira, P.; Cernigoj, U.; Sousa, F.; Queiroz, J.A.; Sousa, Â.. "Chromatographic HPV-16 E6/E7 plasmid vaccine purification employing L-histidine and 1-benzyl-L-histidine affinity ligands". Electrophoresis 38 22-23 (2017): 2975-2980. http://www.scopus.com/inward/record.url?eid=2-s2.0-85036524138&partnerID=MN8TOARS.
    10.1002/elps.201700147
  65. Pereira, P.; Pedro, A.Q.; Queiroz, J.A.; Figueiras, A.R.; Sousa, F.. "New insights for therapeutic recombinant human miRNAs heterologous production: Rhodovolum sulfidophilum vs Escherichia coli". Bioengineered (2017): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014770519&partnerID=MN8TOARS.
    10.1080/21655979.2017.1284710
  66. João Ferreira; Tiago Santos; Patrícia Pereira; Marta C. Corvo; João A. Queiroz; Fani Sousa; Carla Cruz. "Naphthalene amine support for G-quadruplex isolation". The Analyst 142 16 (2017): 2982-2994. https://doi.org/10.1039/C7AN00648A.
    10.1039/C7AN00648A
  67. Gaspar, V.M.; Cruz, C.; Queiroz, J.A.; Pichon, C.; Correia, I.J.; Sousa, F.. "Highly selective capture of minicircle DNA biopharmaceuticals by a novel zinc-histidine peptide conjugate". Separation and Purification Technology 174 (2017): 417-424. http://www.scopus.com/inward/record.url?eid=2-s2.0-84996477404&partnerID=MN8TOARS.
    10.1016/j.seppur.2016.10.054
  68. Coutinho, E.; Batista, C.; Sousa, F.; Queiroz, J.; Costa, D.. "Mitochondrial Gene Therapy: Advances in Mitochondrial Gene Cloning, Plasmid Production, and Nanosystems Targeted to Mitochondria". Molecular Pharmaceutics 14 3 (2017): 626-638. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017578771&partnerID=MN8TOARS.
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  69. D. Bicho; C. Caramelo-Nunes; A. Sousa; F. Sousa; J.A. Queiroz; C.T. Tomaz. "Purification of influenza deoxyribonucleic acid-based vaccine using agmatine monolith". Journal of Chromatography B 1012-1013 (2016): 153-161. https://doi.org/10.1016%2Fj.jchromb.2015.12.036.
    10.1016/j.jchromb.2015.12.036
  70. Matos, T.; Mohamed, E.T.; Queiroz, J.A.; Bülow, L.. "Capto™ Resins for Chromatography of DNA: A Minor Difference in Ligand Composition Greatly Influences the Separation of Guanidyl-Containing Fragments". Chromatographia 79 19-20 (2016): 1277-1282. http://www.scopus.com/inward/record.url?eid=2-s2.0-84980007094&partnerID=MN8TOARS.
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  71. Ferreira, S.; Queiroz, J.A.; Oleastro, M.; Domingues, F.C.. "Insights in the pathogenesis and resistance of Arcobacter: A review". Critical Reviews in Microbiology 42 3 (2016): 364-383. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964596848&partnerID=MN8TOARS.
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  72. Santos, T.; Pereira, P.; Sousa, F.; Queiroz, J.A.; Cruz, C.. "Purification of supercoiled G-quadruplex pDNA for in vitro transcription". Separation and Purification Technology 163 (2016): 59-71. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959323606&partnerID=MN8TOARS.
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  73. Carvalho, J.; Ferreira, J.; Pereira, P.; Coutinho, E.; Guédin, A.; Nottelet, P.; Salgado, G.F.; et al. "Stabilization of novel immunoglobulin switch regions G-quadruplexes by naphthalene and quinoline-based ligands". Tetrahedron 72 9 (2016): 1229-1237. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957542018&partnerID=MN8TOARS.
    10.1016/j.tet.2016.01.022
  74. Pereira, P.; Queiroz, J.A.; Figueiras, A.; Sousa, F.. "Affinity approaches in RNAi-based therapeutics purification". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1021 (2016): 45-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979462515&partnerID=MN8TOARS.
    10.1016/j.jchromb.2016.01.022
  75. Pereira, P.; Pedro, A.Q.; Tomás, J.; Maia, C.J.; Queiroz, J.A.; Figueiras, A.; Sousa, F.. "Advances in time course extracellular production of human pre-miR-29b from Rhodovulum sulfidophilum". Applied Microbiology and Biotechnology 100 8 (2016): 3723-3734. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957660777&partnerID=MN8TOARS.
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  76. Santos, T.; Carvalho, J.; Corvo, M.C.; Cabrita, E.J.; Queiroz, J.A.; Cruz, C.. "L-tryptophan and dipeptide derivatives for supercoiled plasmid DNA purification". International Journal of Biological Macromolecules 87 (2016): 385-396. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960079870&partnerID=MN8TOARS.
    10.1016/j.ijbiomac.2016.02.079
  77. Pereira, P.A.; Tomás, J.F.; Queiroz, J.A.; Figueiras, A.R.; Sousa, F.. "Recombinant pre-miR-29b for Alzheimer's disease therapeutics". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84955595017&partnerID=MN8TOARS.
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  78. Diamantino, T.; Pereira, P.; Queiroz, J.A.; Sousa, Â.; Sousa, F.. "Minicircle DNA purification using a CIM® DEAE-1 monolithic support". Journal of Separation Science 39 18 (2016): 3544-3549. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988447206&partnerID=MN8TOARS.
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  79. Pedro, A.Q.; Correia, F.F.; Santos, F.M.; Espírito-Santo, G.; Gonçalves, A.M.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Biosynthesis and purification of histidine-tagged human soluble catechol-O-methyltransferase". Journal of Chemical Technology and Biotechnology 91 12 (2016): 3035-3044. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962384783&partnerID=MN8TOARS.
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  80. Pereira, P.; Cruz, C.; Queiroz, J.A.; Figueiras, A.; Sousa, F.. "Analysis of pre-MIR-29b binding conditions to amino acids by using a surface plasmon resonance biosensor". Analytical Methods 8 1 (2016): 205-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-84952802419&partnerID=MN8TOARS.
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  81. Queiroz, João. "Development of mitochondrial targeting plasmid DNA nanoparticles: Characterization and in vitro studies". Colloids and Surfaces A: Physicochemical and Engineering Aspects (2015):
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  82. Diana Costa; Wuge H. Briscoe; João Queiroz. "Polyethylenimine coated plasmid DNA–surfactant complexes as potential gene delivery systems". Colloids and Surfaces B: Biointerfaces 133 (2015): 156-163. http://dx.doi.org/10.1016/j.colsurfb.2015.06.005.
    10.1016/j.colsurfb.2015.06.005
  83. Queiroz, João. "Incorporation of antimicrobial peptides on functionalized cotton gauzes for medical applications". Carbohydrate Polymers (2015):
    10.1016/j.carbpol.2015.03.089
  84. Queiroz, João. "Enhanced biosynthesis of plasmid DNA from Escherichia coli VH33 using Box–Behnken design associated to aromatic amino acids pathway". Biochemical Engineering Journal (2015):
    10.1016/j.bej.2015.02.001
  85. Diana Costa; Artur J.M. Valente; João Queiroz. "Plasmid DNA nanogels as photoresponsive materials for multifunctional bio-applications". Journal of Biotechnology 202 (2015): 98-104. https://doi.org/10.1016/j.jbiotec.2014.10.033.
    10.1016/j.jbiotec.2014.10.033
  86. A.M. Almeida; J.A. Queiroz; F. Sousa; A. Sousa. "Optimization of supercoiled HPV-16 E6/E7 plasmid DNA purification with arginine monolith using design of experiments". Journal of Chromatography B 978-979 (2015): 145-150. https://doi.org/10.1016/j.jchromb.2014.12.004.
    10.1016/j.jchromb.2014.12.004
  87. Monteiro, J.P.; Santos, F.M.; Rocha, A.S.; Castro-de-Sousa, J.P.; Queiroz, J.A.; Passarinha, L.A.; Tomaz, C.T.. "Vitreous humor in the pathologic scope: Insights from proteomic approaches". Proteomics - Clinical Applications 9 1-2 (2015): 187-202. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922796593&partnerID=MN8TOARS.
    10.1002/prca.201400133
  88. Costa, D.; Valente, A.J.M.; Queiroz, J.. "Stimuli-responsive polyamine-DNA blend nanogels for co-delivery in cancer therapy". Colloids and Surfaces B: Biointerfaces 132 (2015): 194-201. http://www.scopus.com/inward/record.url?eid=2-s2.0-84936764313&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2015.04.064
  89. Amorim, L.F.A.; Sousa, F.; Queiroz, J.A.; Cruz, C.; Sousa, A.. "Screening of l -histidine-based ligands to modify monolithic supports and selectively purify the supercoiled plasmid DNA isoform". Journal of Molecular Recognition 28 6 (2015): 349-358. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928111894&partnerID=MN8TOARS.
    10.1002/jmr.2449
  90. Gaspar, V.M.; Costa, E.C.; Queiroz, J.A.; Pichon, C.; Sousa, F.; Correia, I.J.. "Folate-targeted multifunctional amino acid-chitosan nanoparticles for improved cancer therapy". Pharmaceutical Research 32 2 (2015): 562-577. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921485287&partnerID=MN8TOARS.
    10.1007/s11095-014-1486-0
  91. Pedro, A.Q.; Oppolzer, D.; Bonifácio, M.J.; Maia, C.J.; Queiroz, J.A.; Passarinha, L.A.. "Evaluation of MutS and Mut+ Pichia pastoris Strains for Membrane-Bound Catechol-O-Methyltransferase Biosynthesis". Applied Biochemistry and Biotechnology 175 8 (2015): 3840-3855. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939997453&partnerID=MN8TOARS.
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  92. Silva, M.S.; Graça, V.C.; Reis, L.V.; Santos, P.F.; Silvestre, S.; Granadeiro, L.; Almeida, P.; Queiroz, J.A.; Sousa, F.. "3,3'-Diamino-N-methyldipropylamine as a versatile affinity ligand". Journal of Separation Science 38 5 (2015): 732-740. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924169977&partnerID=MN8TOARS.
    10.1002/jssc.201400656
  93. Mota, É.; Sousa, F.; Queiroz, J.A.; Cruz, C.. "Quantitative analysis of the interaction between l-methionine derivative and oligonucleotides". Journal of Biochemistry 157 4 (2015): 261-270. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944458182&partnerID=MN8TOARS.
    10.1093/jb/mvu073
  94. Castilho, P.H.; Correia, T.R.; Pessoa De Amorim, M.T.; Escobar, I.C.; Queiroz, J.A.; Correia, I.J.; Morão, A.M.. "Modification of microfiltration membranes by hydrogel impregnation for pDNA purification". Journal of Applied Polymer Science 132 21 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84924062645&partnerID=MN8TOARS.
    10.1002/app.41610
  95. Gaspar, V.; De Melo-Diogo, D.; Costa, E.; Moreira, A.; Queiroz, J.; Pichon, C.; Correia, I.; Sousa, F.. "Minicircle DNA vectors for gene therapy: Advances and applications". Expert Opinion on Biological Therapy 15 3 (2015): 353-379. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923080078&partnerID=MN8TOARS.
    10.1517/14712598.2015.996544
  96. Jozala, A.F.; De Lencastre Novaes, L.C.; Mazzola, P.G.; Oliveira-Nascimento, L.; Vessoni Penna, T.C.; Teixeira, J.A.; Passarinha, L.A.; Queiroz, J.A.; Pessoa, A.. "Low-cost purification of nisin from milk whey to a highly active product". Food and Bioproducts Processing 93 (2015): 115-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922248464&partnerID=MN8TOARS.
    10.1016/j.fbp.2013.12.003
  97. Gaspar, V.M.; Baril, P.; Costa, E.C.; De Melo-Diogo, D.; Foucher, F.; Queiroz, J.A.; Sousa, F.; Pichon, C.; Correia, I.J.. "Bioreducible poly(2-ethyl-2-oxazoline)-PLA-PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin". Journal of Controlled Release 213 (2015): 175-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937550858&partnerID=MN8TOARS.
    10.1016/j.jconrel.2015.07.011
  98. Barroso, M.; Gallardo, E.; Queiroz, J.A.. "The role of liquid-phase microextraction techniques in bioanalysis". Bioanalysis 7 17 (2015): 2195-2201. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943245770&partnerID=MN8TOARS.
    10.4155/bio.15.136
  99. Ferreira, S.; Carvalho, J.; Valente, J.F.A.; Corvo, M.C.; Cabrita, E.J.; Sousa, F.; Queiroz, J.A.; Cruz, C.. "Affinity analysis and application of dipeptides derived from l-tyrosine in plasmid purification". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1006 (2015): 47-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946410380&partnerID=MN8TOARS.
    10.1016/j.jchromb.2015.10.025
  100. Matos, T.; Silva, G.; Queiroz, J.A.; Bülow, L.. "Preparative isolation of polymerase chain reaction products using mixed-mode chromatography". Analytical Biochemistry 489 (2015): 73-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942163159&partnerID=MN8TOARS.
    10.1016/j.ab.2015.08.009
  101. Bicho, D.; Santos, B.F.; Caramelo-Nunes, C.; Sousa, A.; Sousa, F.; Queiroz, J.A.; Tomaz, C.T.. "Application of ethylenediamine monolith to purify a hemagglutinin influenza deoxyribonucleic acid-based vaccine". Separation and Purification Technology 154 (2015): 320-327. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943535397&partnerID=MN8TOARS.
    10.1016/j.seppur.2015.09.046
  102. Pedro, A.Q.; Pereira, P.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Purification of Membrane-Bound Catechol-O-Methyltransferase by Arginine-Affinity Chromatography". Chromatographia 78 21-22 (2015): 1339-1348. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945473527&partnerID=MN8TOARS.
    10.1007/s10337-015-2970-3
  103. Gaspar, V.M.; Moreira, A.F.; Costa, E.C.; Queiroz, J.A.; Sousa, F.; Pichon, C.; Correia, I.J.. "Gas-generating TPGS-PLGA microspheres loaded with nanoparticles (NIMPS) for co-delivery of minicircle DNA and anti-tumoral drugs". Colloids and Surfaces B: Biointerfaces 134 (2015): 287-294. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937882582&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2015.07.004
  104. Pedro, A.Q.; Martins, L.M.; Dias, J.M.L.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "An artificial neural network for membrane-bound catechol-O-methyltransferase biosynthesis with Pichia pastoris methanol-induced cultures". Microbial Cell Factories 14 1 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84938603979&partnerID=MN8TOARS.
    10.1186/s12934-015-0304-7
  105. Queiroz, João. "Pharmaceutical-grade pre-miR-29 purification using an agmatine monolithic support". Journal of Chromatography A (2014):
    10.1016/j.chroma.2014.09.080
  106. Diana Bicho; Ângela Sousa; Fani Sousa; João Queiroz; Cãndida Tomaz. "Effect of chromatographic conditions and plasmid DNA size on the dynamic binding capacity of a monolithic support". Journal of Separation Science 37 17 (2014): 2284-2292. https://doi.org/10.1002/jssc.201400127.
    10.1002/jssc.201400127
  107. Queiroz, João. "Development of fed-batch profiles for efficient biosynthesis of catechol-O-methyltransferase". Biotechnology Reports (2014):
    10.1016/j.btre.2014.05.005
  108. Vítor M. Gaspar; Cristine Gonçalves; Duarte de Melo-Diogo; Elisabete C. Costa; João A. Queiroz; Chantal Pichon; Fani Sousa; Ilídio J. Correia. "Poly(2-ethyl-2-oxazoline)–PLA-g–PEI amphiphilic triblock micelles for co-delivery of minicircle DNA and chemotherapeutics". Journal of Controlled Release 189 (2014): 90-104. https://doi.org/10.1016/j.jconrel.2014.06.040.
    10.1016/j.jconrel.2014.06.040
  109. Rocha, A.S.; Santos, F.M.; Monteiro, J.P.; Castro-de-Sousa, J.P.; Queiroz, J.A.; Tomaz, C.T.; Passarinha, L.A.. "Trends in proteomic analysis of human vitreous humor samples". Electrophoresis 35 17 (2014): 2495-2508. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906939868&partnerID=MN8TOARS.
    10.1002/elps.201400049
  110. Gonçalves, A.M.; Pedro, A.Q.; Santos, F.M.; Martins, L.M.; Maia, C.J.; Queiroz, J.A.; Passarinha, L.A.. "Trends in protein-based biosensor assemblies for drug screening and pharmaceutical kinetic studies". Molecules 19 8 (2014): 12461-12485. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906708189&partnerID=MN8TOARS.
    10.3390/molecules190812461
  111. Afonso, A.; Pereira, P.; Queiroz, J.A.; Sousa, T.; Sousa, F.. "Purification of pre-miR-29 by a new O-phospho-l-tyrosine affinity chromatographic strategy optimized using design of experiments". Journal of Chromatography A 1343 (2014): 119-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899989051&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.03.071
  112. Nunes, J.C.; Pessoa de Amorim, M.T.; Escobar, I.C.; Queiroz, J.A.; Morão, A.M.. "Plasmid DNA/RNA separation by ultrafiltration: Modeling and application study". Journal of Membrane Science 463 (2014): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897952490&partnerID=MN8TOARS.
    10.1016/j.memsci.2014.03.036
  113. Matos, T.; Queiroz, J.A.; Bülow, L.. "Plasmid DNA purification using a multimodal chromatography resin". Journal of Molecular Recognition 27 4 (2014): 184-189. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897594310&partnerID=MN8TOARS.
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  114. Costa, D.; Valente, A.J.M.; Miguel, M.G.; Queiroz, J.. "Plasmid DNA microgels for drug/gene co-delivery: A promising approach for cancer therapy". Colloids and Surfaces A: Physicochemical and Engineering Aspects 442 (2014): 181-190. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895062827&partnerID=MN8TOARS.
    10.1016/j.colsurfa.2013.02.048
  115. Costa, D.; Valente, A.J.M.; Miguel, M.G.; Queiroz, J.. "Plasmid DNA hydrogels for biomedical applications". Advances in Colloid and Interface Science 205 (2014): 257-264. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900367905&partnerID=MN8TOARS.
    10.1016/j.cis.2013.08.002
  116. Cruz, C.; Boto, R.E.F.; Drzazga, A.K.; Almeida, P.; Queiroz, J.A.. "NMR screening of new carbocyanine dyes as ligands for affinity chromatography". Journal of Molecular Recognition 27 4 (2014): 197-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897606172&partnerID=MN8TOARS.
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  117. Nunes, C.; Sousa, A.; Nunes, J.C.; Morão, A.M.; Sousa, F.; Queiroz, J.A.. "Supercoiled plasmid DNA purification by integrating membrane technology with a monolithic chromatography". Journal of Separation Science 37 11 (2014): 1229-1236. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902117888&partnerID=MN8TOARS.
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  118. Valente, J.F.A.; Sousa, A.; Queiroz, J.A.; Sousa, F.. "Selective purification of supercoiled p53-encoding pDNA with l-methionine-agarose matrix". Analytical Biochemistry 459 (2014): 61-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902657783&partnerID=MN8TOARS.
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  119. Martins, R.; Queiroz, J.A.; Sousa, F.. "Ribonucleic acid purification". Journal of Chromatography A 1355 (2014): 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904302278&partnerID=MN8TOARS.
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  120. Santos, J.; Sousa, F.; Queiroz, J.; Costa, D.. "Rhodamine based plasmid DNA nanoparticles for mitochondrial gene therapy". Colloids and Surfaces B: Biointerfaces 121 (2014): 129-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902972220&partnerID=MN8TOARS.
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  121. Ferreira, S.; Silva, F.; Queiroz, J.A.; Oleastro, M.; Domingues, F.C.. "Resveratrol against Arcobacter butzleri and Arcobacter cryaerophilus: Activity and effect on cellular functions". International Journal of Food Microbiology 180 (2014): 62-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899700961&partnerID=MN8TOARS.
    10.1016/j.ijfoodmicro.2014.04.004
  122. Correia, F.F.; Santos, F.M.; Pedro, A.Q.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.P.. "Recovery of biological active catechol-O-methyltransferase isoforms from Q-sepharose". Journal of Separation Science 37 1-2 (2014): 20-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893944749&partnerID=MN8TOARS.
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  123. Cruz, C.; Sousa, Â.; Mota, É.; Sousa, F.; Queiroz, J.A.. "Quantitative analysis of histamine- and agmatine-DNA interactions using surface plasmon resonance". International Journal of Biological Macromolecules 70 (2014): 131-137. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904357281&partnerID=MN8TOARS.
    10.1016/j.ijbiomac.2014.06.044
  124. Pereira, P.; Sousa, Â.; Queiroz, J.; Correia, I.; Figueiras, A.; Sousa, F.. "Purification of pre-miR-29 by arginine-affinity chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 951-952 1 (2014): 16-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893705000&partnerID=MN8TOARS.
    10.1016/j.jchromb.2014.01.020
  125. Graça, V.C.; Silva, M.S.; Reis, L.V.; Sousa, F.; Almeida, P.; Queiroz, J.A.; Santos, P.F.. "Ethylenediamine-Derived Chromatographic Ligand to Separate BSA, Lysozyme, and RNase A". Chromatographia 77 21-22 (2014): 1529-1537. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911950967&partnerID=MN8TOARS.
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  126. Sousa, T.; Pereira, P.; Sousa, F.; Queiroz, J.A.. "Binding mechanisms for histamine and agmatine ligands in plasmid deoxyribonucleic acid purifications". Journal of Chromatography A 1366 (2014): 110-119. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907969355&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.09.031
  127. Silva-Dias, A.; Palmeira-De-Oliveira, A.; Miranda, I.M.; Branco, J.; Cobrado, L.; Monteiro-Soares, M.; Queiroz, J.A.; Pina-Vaz, C.; Rodrigues, A.G.. "Anti-biofilm activity of low-molecular weight chitosan hydrogel against Candida species". Medical Microbiology and Immunology 203 1 (2014): 25-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894271250&partnerID=MN8TOARS.
    10.1007/s00430-013-0311-4
  128. Gomes, A.P.; Mano, J.F.; Queiroz, J.A.; Gouveia, I.C.. "New biomaterial based on cotton with incorporated Biomolecules". Journal of Applied Polymer Science 131 15 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84900478060&partnerID=MN8TOARS.
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  129. Pereira, P.; Sousa, T.; Queiroz, J.; Figueiras, A.; Sousa, F.. "New approach for purification of pre-miR-29 using lysine-affinity chromatography". Journal of Chromatography A 1331 (2014): 129-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896715699&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.01.033
  130. Mota, E.; Sousa, F.; Sousa, Â.; Queiroz, J.A.; Cruz, C.. "Molecular recognition of oligonucleotides and plasmid DNA by L-methionine". Journal of Molecular Recognition 27 10 (2014): 588-596. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906888435&partnerID=MN8TOARS.
    10.1002/jmr.2382
  131. Ferreira, S.; Júlio, C.; Queiroz, J.A.; Domingues, F.C.; Oleastro, M.. "Molecular diagnosis of Arcobacter and Campylobacter in diarrhoeal samples among Portuguese patients". Diagnostic Microbiology and Infectious Disease 78 3 (2014): 220-225. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893720252&partnerID=MN8TOARS.
    10.1016/j.diagmicrobio.2013.11.021
  132. Matos, T.; Johansson, H.-O.; Queiroz, J.A.; Bulow, L.. "Isolation of PCR DNA fragments using aqueous two-phase systems". Separation and Purification Technology 122 (2014): 144-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888615757&partnerID=MN8TOARS.
    10.1016/j.seppur.2013.11.014
  133. Gaspar, V.M.; Maia, C.J.; Queiroz, J.A.; Pichon, C.; Correia, I.J.; Sousa, F.. "Improved minicircle DNA biosynthesis for gene therapy applications". Human Gene Therapy Methods 25 2 (2014): 93-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898737624&partnerID=MN8TOARS.
    10.1089/hgtb.2013.020
  134. Sousa, A.; Almeida, A.M.; Cernigoj, U.; Sousa, F.; Queiroz, J.A.. "Histamine monolith versatility to purify supercoiled plasmid deoxyribonucleic acid from Escherichia coli lysate". Journal of Chromatography A 1355 (2014): 125-133. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904286739&partnerID=MN8TOARS.
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  135. Ferreira, S.; Queiroz, J.A.; Oleastro, M.; Domingues, F.C.. "Genotypic and phenotypic features of Arcobacter butzleri pathogenicity". Microbial Pathogenesis 76 (2014): 19-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907511687&partnerID=MN8TOARS.
    10.1016/j.micpath.2014.09.004
  136. Ferreira, S.; Fraqueza, M.J.; Queiroz, J.A.; Domingues, F.C.; Oleastro, M.. "Genetic diversity, antibiotic resistance and biofilm-forming ability of Arcobacter butzleri isolated from poultry and environment from a Portuguese slaughterhouse". International Journal of Food Microbiology 162 1 (2013): 82-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873867619&partnerID=MN8TOARS.
    10.1016/j.ijfoodmicro.2013.01.003
  137. Rodrigues, M.; Alves, G.; Rocha, M.; Queiroz, J.; Falcão, A.. "First liquid chromatographic method for the simultaneous determination of amiodarone and desethylamiodarone in human plasma using microextraction by packed sorbent (MEPS) as sample preparation procedure". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 913-914 (2013): 90-97. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872397093&partnerID=MN8TOARS.
    10.1016/j.jchromb.2012.11.028
  138. Da Fonseca, B.M.; Moreno, I.E.D.; Barroso, M.; Costa, S.; Queiroz, J.A.; Gallardo, E.. "Determination of seven selected antipsychotic drugs in human plasma using microextraction in packed sorbent and gas chromatography-tandem mass spectrometry". Analytical and Bioanalytical Chemistry 405 12 (2013): 3953-3963. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886842307&partnerID=MN8TOARS.
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  139. Gaspar, V.M.; Marques, J.G.; Sousa, F.; Louro, R.O.; Queiroz, J.A.; Correia, I.J.. "Biofunctionalized nanoparticles with pH-responsive and cell penetrating blocks for gene delivery". Nanotechnology 24 27 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84879292912&partnerID=MN8TOARS.
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  140. Matos, T.; Queiroz, J.A.; Bülow, L.. "Binding and elution behavior of small deoxyribonucleic acid fragments on a strong anion-exchanger multimodal chromatography resin". Journal of Chromatography A 1302 (2013): 40-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880278506&partnerID=MN8TOARS.
    10.1016/j.chroma.2013.05.044
  141. Cruz, C.; Santos, S.D.; Cabrita, E.J.; Queiroz, J.A.. "Binding analysis between L-histidine immobilized and oligonucleotides by SPR and NMR". International Journal of Biological Macromolecules 56 (2013): 175-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875107732&partnerID=MN8TOARS.
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  142. Palmeira-de-Oliveira, A.; Palmeira-de-Oliveira, R.; Gaspar, C.; Salgueiro, L.; Cavaleiro, C.; Martinez-de-Oliveira, M.; Queiroz, J.A.; Rodrigues, A.G.. "Association of Thymbra capitata essential oil and chitosan (TCCH hydrogel): A putative therapeutic tool for the treatment of vulvovaginal candidosis". Flavour and Fragrance Journal 28 6 (2013): 354-359. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885850985&partnerID=MN8TOARS.
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  143. Soares, A.; Queiroz, J.A.; Sousa, F.; Sousa, A.. "Purification of human papillomavirus 16 E6/E7 plasmid deoxyribonucleic acid-based vaccine using an arginine modified monolithic support". Journal of Chromatography A 1320 (2013): 72-79. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887611735&partnerID=MN8TOARS.
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  144. Silva, M.S.; Graça, V.C.; Reis, L.V.; Santos, P.F.; Almeida, P.; Queiroz, J.A.; Sousa, F.. "Protein purification by aminosquarylium cyanine dye-affinity chromatography". Biomedical Chromatography 27 12 (2013): 1671-1679. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887190801&partnerID=MN8TOARS.
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  145. Cruz, C.; Cairrão, E.; Lourenço, O.; Almeida, P.; Verde, I.; Queiroz, J.A.. "Polyazamacrocycles as Potential Antitumor Agents for Human Prostate Cancer Cells". Chemical Biology and Drug Design 81 4 (2013): 517-526. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875652204&partnerID=MN8TOARS.
    10.1111/cbdd.12098
  146. Gonçalves, A.M.; Pedro, A.Q.; Maia, C.; Sousa, F.; Queiroz, J.A.; Passarinha, L.A.. "Pichia pastoris: A recombinant microfactory for antibodies and human membrane proteins". Journal of Microbiology and Biotechnology 23 5 (2013): 587-601. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877343772&partnerID=MN8TOARS.
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  147. Santos, F.M.; Pedro, A.Q.; Soares, R.F.; Martins, R.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Performance of hydrophobic interaction ligands for human membrane-bound catechol-O-methyltransferase purification". Journal of Separation Science 36 11 (2013): 1693-1702. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878757945&partnerID=MN8TOARS.
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  148. Matos, T.; Senkbeil, S.; Mendonça, A.; Queiroz, J.A.; Kutter, J.P.; Bulow, L.. "Nucleic acid and protein extraction from electropermeabilized E. coli cells on a microfluidic chip". Analyst 138 24 (2013): 7347-7353. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887544786&partnerID=MN8TOARS.
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  149. Martins, R.; Queiroz, J.A.; Sousa, F.. "New approach in RNA quantification using arginine-affinity chromatography: Potential application in eukaryotic and chemically synthesized RNA". Analytical and Bioanalytical Chemistry 405 27 (2013): 8849-8858. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893683678&partnerID=MN8TOARS.
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  150. Gomes, A.P.; Mano, J.F.; Queiroz, J.A.; Gouveia, I.C.. "Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers: A new strategy to develop bioactive textiles". Polymers for Advanced Technologies 24 11 (2013): 1005-1010. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885929826&partnerID=MN8TOARS.
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  151. Oppolzer, D.; Moreno, I.; da Fonseca, B.; Passarinha, L.; Barroso, M.; Costa, S.; Queiroz, J.A.; Gallardo, E.. "Analytical approach to determine biogenic amines in urine using microextraction in packed syringe and liquid chromatography coupled to electrochemical detection". Biomedical Chromatography 27 5 (2013): 608-614. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876315284&partnerID=MN8TOARS.
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  152. Moreno, I.; Da Fonseca, B.; Oppolzer, D.; Martinho, A.; Barroso, M.; Cruz, A.; Queiroz, J.A.; Gallardo, E.. "Analysis of Salvinorin A in urine using microextraction in packed syringe and GC-MS/MS". Bioanalysis 5 6 (2013): 661-668. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875034173&partnerID=MN8TOARS.
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  153. Cruz, C.; Sousa, A.; Sousa, F.; Queiroz, J.A.. "Affinity analysis between immobilized l-arginine and plasmid isoforms provided by surface plasmon resonance". Analytical Methods 5 7 (2013): 1682-1686. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879509327&partnerID=MN8TOARS.
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  154. Rodrigues, M.; Alves, G.; Ferreira, A.; Queiroz, J.; Falcão, A.. "A rapid HPLC method for the simultaneous determination of amiodarone and its major metabolite in rat plasma and tissues: A useful tool for pharmacokinetic studies". Journal of Chromatographic Science 51 4 (2013): 361-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874767501&partnerID=MN8TOARS.
    10.1093/chromsci/bms149
  155. Alves, G.; Rodrigues, M.; Fortuna, A.; Falcão, A.; Queiroz, J.. "A critical review of microextraction by packed sorbent as a sample preparation approach in drug bioanalysis". Bioanalysis 5 11 (2013): 1409-1442. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878872813&partnerID=MN8TOARS.
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  156. Correia, T.R.; Antunes, B.P.; Castilho, P.H.; Nunes, J.C.; Pessoa De Amorim, M.T.; Escobar, I.C.; Queiroz, J.A.; Correia, I.J.; Morão, A.M.. "A bi-layer electrospun nanofiber membrane for plasmid DNA recovery from fermentation broths". Separation and Purification Technology 112 (2013): 20-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876890203&partnerID=MN8TOARS.
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  157. Queiroz, J.A.; Gallardo, E.; Barroso, M.. "What are the recent advances in forensic oral fluid bioanalysis?". Bioanalysis 5 17 (2013): 2077-2079. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883094366&partnerID=MN8TOARS.
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  158. Gaspar, V.M.; Cruz, C.; Queiroz, J.A.; Pichon, C.; Correia, I.J.; Sousa, F.. "Sensitive detection of peptide-minicircle DNA interactions by surface plasmon resonance". Analytical Chemistry 85 4 (2013): 2304-2311. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874041051&partnerID=MN8TOARS.
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  159. Mota, É.; Sousa, Â.; Cernigoj, U.; Queiroz, J.A.; Tomaz, C.T.; Sousa, F.. "Rapid quantification of supercoiled plasmid deoxyribonucleic acid using a monolithic ion exchanger". Journal of Chromatography A 1291 (2013): 114-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876791056&partnerID=MN8TOARS.
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  160. Moreno, I.E.D.; da Fonseca, B.M.; Magalhães, A.R.; Geraldes, V.S.; Queiroz, J.A.; Barroso, M.; Costa, S.; Gallardo, E.. "Rapid determination of piperazine-type stimulants in human urine by microextraction in packed sorbent after method optimization using a multivariate approach". Journal of Chromatography A 1222 (2012): 116-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855577615&partnerID=MN8TOARS.
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  161. Nunes, J.C.; Morão, A.M.; Nunes, C.; Pessoa de Amorim, M.T.; Escobar, I.C.; Queiroz, J.A.. "Plasmid DNA recovery from fermentation broths by a combined process of micro- and ultrafiltration: Modeling and application". Journal of Membrane Science 415-416 (2012): 24-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864744326&partnerID=MN8TOARS.
    10.1016/j.memsci.2012.04.055
  162. Costa, D.; Valente, A.J.M.; Miguel, M.G.; Queiroz, J.. "Plasmid dna microgels for a therapeutical strategy combining the delivery of genes and anticancer drugs". Macromolecular Bioscience 12 9 (2012): 1243-1252. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865803070&partnerID=MN8TOARS.
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  163. Silva, F.; Queiroz, J.A.; Domingues, F.C.. "Plasmid DNA fermentation strategies: Influence on plasmid stability and cell physiology". Applied Microbiology and Biotechnology 93 6 (2012): 2571-2580. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862280267&partnerID=MN8TOARS.
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  164. Silva, R.; Ferreira, S.; Bonifácio, M.J.; Dias, J.M.L.; Queiroz, J.A.; Passarinha, L.A.. "Optimization of fermentation conditions for the production of human soluble catechol-O-methyltransferase by Escherichia coli using artificial neural network". Journal of Biotechnology 160 3-4 (2012): 161-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864071138&partnerID=MN8TOARS.
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  165. Palmeira-De-Oliveira, A.; Gaspar, C.; Palmeira-De-Oliveira, R.; Silva-Dias, A.; Salgueiro, L.; Cavaleiro, C.; Pina-Vaz, C.; et al. "The anti-Candida activity of Thymbra capitata essential oil: Effect upon pre-formed biofilm". Journal of Ethnopharmacology 140 2 (2012): 379-383. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858003164&partnerID=MN8TOARS.
    10.1016/j.jep.2012.01.029
  166. Costa, D.; Queiroz, J.; Miguel, M.G.; Lindman, B.. "Swelling behavior of a new biocompatible plasmid DNA hydrogel". Colloids and Surfaces B: Biointerfaces 92 (2012): 106-112. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856089000&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2011.11.038
  167. Gomes, A.P.; Mano, J.F.; Queiroz, J.A.; Gouveia, I.C.. "Layer-by-Layer Deposition of Antibacterial Polyelectrolytes on Cotton Fibres". Journal of Polymers and the Environment 20 4 (2012): 1084-1094. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871300327&partnerID=MN8TOARS.
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  169. Silva, F.; Queiroz, J.A.; Domingues, F.C.. "Evaluating metabolic stress and plasmid stability in plasmid DNA production by Escherichia coli". Biotechnology Advances 30 3 (2012): 691-708. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857499822&partnerID=MN8TOARS.
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  170. Moreno, I.E.D.; da Fonseca, B.M.; Barroso, M.; Costa, S.; Queiroz, J.A.; Gallardo, E.. "Determination of piperazine-type stimulants in human urine by means of microextraction in packed sorbent and high performance liquid chromatography-diode array detection". Journal of Pharmaceutical and Biomedical Analysis 61 (2012): 93-99. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856118885&partnerID=MN8TOARS.
    10.1016/j.jpba.2011.12.004
  171. da Fonseca, B.M.; Moreno, I.E.D.; Magalhães, A.R.; Barroso, M.; Queiroz, J.A.; Ravara, S.; Calheiros, J.; Gallardo, E.. "Determination of biomarkers of tobacco smoke exposure in oral fluid using solid-phase extraction and gas chromatography-tandem mass spectrometry". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 889-890 (2012): 116-122. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858281192&partnerID=MN8TOARS.
    10.1016/j.jchromb.2012.02.006
  172. Sousa, Â.; Sousa, F.; Queiroz, J.A.. "Advances in chromatographic supports for pharmaceutical-grade plasmid DNA purification". Journal of Separation Science 35 22 (2012): 3046-3058. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870040472&partnerID=MN8TOARS.
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  173. Martins, R.; Maia, C.J.; Queiroz, J.A.; Sousa, F.. "A new strategy for RNA isolation from eukaryotic cells using arginine affinity chromatography". Journal of Separation Science 35 22 (2012): 3217-3226. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870045405&partnerID=MN8TOARS.
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  174. Cruz, C.; Sousa, A.; Sousa, F.; Queiroz, J.A.. "Study of the specific interaction between l-methionine chromatography support and nucleotides". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 909 (2012): 1-5. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868249738&partnerID=MN8TOARS.
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  175. Ferreira, S.; Santos, J.; Duarte, A.; Duarte, A.P.; Queiroz, J.A.; Domingues, F.C.. "Screening of antimicrobial activity of Cistus ladanifer and Arbutus unedo extracts". Natural Product Research 26 16 (2012): 1558-1560. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865161236&partnerID=MN8TOARS.
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  176. Barroso, M.; Moreno, I.; Da Fonseca, B.; Queiroz, J.A.; Gallardo, E.. "Role of microextraction sampling procedures in forensic toxicology". Bioanalysis 4 14 (2012): 1805-1826. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864969793&partnerID=MN8TOARS.
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  177. Sousa, A.; Bicho, D.; Tomaz, C.T.; Sousa, F.; Queiroz, J.A.. "Performance of a non-grafted monolithic support for purification of supercoiled plasmid DNA". Journal of Chromatography A 1218 13 (2011): 1701-1706. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952363162&partnerID=MN8TOARS.
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  178. Gaspar, V.M.; Correia, I.J.; Sousa, A.; Silva, F.; Paquete, C.M.; Queiroz, J.A.; Sousa, F.. "Nanoparticle mediated delivery of pure P53 supercoiled plasmid DNA for gene therapy". Journal of Controlled Release 156 2 (2011): 212-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-81255211172&partnerID=MN8TOARS.
    10.1016/j.jconrel.2011.08.007
  179. Morão, A.M.; Nunes, J.C.; Sousa, F.; Pessoa de Amorim, M.T.; Escobar, I.C.; Queiroz, J.A.. "Ultrafiltration of supercoiled plasmid DNA: Modeling and application". Journal of Membrane Science 378 1-2 (2011): 280-289. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959984677&partnerID=MN8TOARS.
    10.1016/j.memsci.2011.05.017
  180. Silva, F.; Lourenço, O.; Queiroz, J.A.; Domingues, F.C.. "Bacteriostatic versus bactericidal activity of ciprofloxacin in Escherichia coli assessed by flow cytometry using a novel far-red dye". Journal of Antibiotics 64 4 (2011): 321-325. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955560989&partnerID=MN8TOARS.
    10.1038/ja.2011.5
  181. Paulo, L.; Oleastro, M.; Gallardo, E.; Queiroz, J.A.; Domingues, F.. "Anti-Helicobacter pylori and urease inhibitory activities of resveratrol and red wine". Food Research International 44 4 (2011): 964-969. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955591155&partnerID=MN8TOARS.
    10.1016/j.foodres.2011.02.017
  182. Cruz, C.; Cabrita, E.J.; Queiroz, J.A.. "Analysis of nucleotides binding to chromatography supports provided by nuclear magnetic resonance spectroscopy". Journal of Chromatography A 1218 22 (2011): 3559-3564. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955744343&partnerID=MN8TOARS.
    10.1016/j.chroma.2011.03.055
  183. Costa, S.R.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Analysis of hSCOMT adsorption in bioaffinity chromatography with immobilized amino acids: The influence of pH and ionic strength". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 879 19 (2011): 1704-1706. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955917506&partnerID=MN8TOARS.
    10.1016/j.jchromb.2011.03.056
  184. Ferreira, S.; Gil, N.; Queiroz, J.A.; Duarte, A.P.; Domingues, F.C.. "An evaluation of the potential of Acacia dealbata as raw material for bioethanol production". Bioresource Technology 102 7 (2011): 4766-4773. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951952719&partnerID=MN8TOARS.
    10.1016/j.biortech.2011.01.051
  185. Pedro, A.Q.; Bonifácio, M.J.; Queiroz, J.A.; Maia, C.J.; Passarinha, L.A.. "A novel prokaryotic expression system for biosynthesis of recombinant human membrane-bound catechol-O-methyltransferase". Journal of Biotechnology 156 2 (2011): 141-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054037915&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2011.08.022
  186. Silva, F.; Loureno, O.; Maia, C.; Queiroz, J.A.; Domingues, F.C.. "Impact of plasmid induction strategy on overall plasmid DNA yield and E. coli physiology using flow cytometry and real-time PCR". Process Biochemistry 46 1 (2011): 174-181. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650243570&partnerID=MN8TOARS.
    10.1016/j.procbio.2010.08.001
  187. Sousa, A.; Sousa, F.; Queiroz, J.A.. "Impact of lysine-affinity chromatography on supercoiled plasmid DNA purification". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 879 30 (2011): 3507-3515. http://www.scopus.com/inward/record.url?eid=2-s2.0-80555149385&partnerID=MN8TOARS.
    10.1016/j.jchromb.2011.09.032
  188. Barroso, M.; Gallardo, E.; Vieira, D.N.; López-Rivadulla, M.; Queiroz, J.A.. "Hair: A complementary source of bioanalytical information in forensic toxicology". Bioanalysis 3 1 (2011): 67-79. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951875533&partnerID=MN8TOARS.
    10.4155/bio.10.171
  189. Costa, D.; Valente, A.J.M.; Miguel, M.G.; Queiroz, J.. "Gel network photodisruption: A new strategy for the codelivery of plasmid DNA and drugs". Langmuir 27 22 (2011): 13780-13789. http://www.scopus.com/inward/record.url?eid=2-s2.0-80755159554&partnerID=MN8TOARS.
    10.1021/la2026285
  190. Gaspar, V.M.; Sousa, F.; Queiroz, J.A.; Correia, I.J.. "Formulation of chitosan-TPP-pDNA nanocapsules for gene therapy Applications". Nanotechnology 22 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79251591020&partnerID=MN8TOARS.
    10.1088/0957-4484/22/1/015101
  191. Paulo, L.; Domingues, F.; Queiroz, J.A.; Gallardo, E.. "Development and validation of an analytical method for the determination of trans - And cis -resveratrol in wine: Analysis of its contents in 186 Portuguese red wines". Journal of Agricultural and Food Chemistry 59 6 (2011): 2157-2168. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952773359&partnerID=MN8TOARS.
    10.1021/jf105004y
  192. Silva, F.; Ferreira, S.; Queiroz, J.A.; Domingues, F.C.. "Coriander (Coriandrum sativum L.) essential oil: Its antibacterial activity and mode of action evaluated by flow cytometry". Journal of Medical Microbiology 60 10 (2011): 1479-1486. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053159965&partnerID=MN8TOARS.
    10.1099/jmm.0.034157-0
  193. Barroso, M.; Gallardo, E.; Vieira, D.N.; Queiroz, J.A.; López-Rivadulla, M.. "Bioanalytical procedures and recent developments in the determination of opiates/opioids in human biological samples". Analytical and Bioanalytical Chemistry 400 6 (2011): 1665-1690. http://www.scopus.com/inward/record.url?eid=2-s2.0-79956286123&partnerID=MN8TOARS.
    10.1007/s00216-011-4888-4
  194. Palmeira-de-Oliveira, A.; Passarinha, L.A.; Gaspar, C.; Palmeira-de-Oliveira, R.; Sarmento, B.; Martinez-de-Oliveira, J.; Pina-Vaz, C.; Rodrigues, A.G.; Queiroz, J.A.. "The relationship between Candida species charge density and chitosan activity evaluated by ion-exchange chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 879 31 (2011): 3749-3751. http://www.scopus.com/inward/record.url?eid=2-s2.0-82955198487&partnerID=MN8TOARS.
    10.1016/j.jchromb.2011.07.034
  195. Cruz, C.; Cairrao, E.; Silvestre, S.; Breitenfeld, L.; Almeida, P.; Queiroz, J.A.. "Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds". PLoS ONE 6 11 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-81455144577&partnerID=MN8TOARS.
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  196. Sousa, F.; Queiroz, J.A.. "Supercoiled plasmid quality assessment by analytical arginine-affinity chromatography". Journal of Chromatography A 1218 1 (2011): 124-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650417249&partnerID=MN8TOARS.
    10.1016/j.chroma.2010.11.002
  197. Sousa, A.; Tomaz, C.T.; Sousa, F.; Queiroz, J.A.. "Successful application of monolithic innovative technology using a carbonyldiimidazole disk to purify supercoiled plasmid DNA suitable for pharmaceutical applications". Journal of Chromatography A 1218 46 (2011): 8333-8343. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054865157&partnerID=MN8TOARS.
    10.1016/j.chroma.2011.09.033
  198. Cruz, C.; Boto, R.E.F.; Almeida, P.; Queiroz, J.A.. "Study of specific interaction between nucleotides and dye support by nuclear magnetic resonance". Journal of Molecular Recognition 24 6 (2011): 975-980. http://www.scopus.com/inward/record.url?eid=2-s2.0-80155148696&partnerID=MN8TOARS.
    10.1002/jmr.1144
  199. Cruz, C.; Cabrita, E.J.; Queiroz, J.A.. "Screening nucleotide binding to amino acid-coated supports by surface plasmon resonance and nuclear magnetic resonance". Analytical and Bioanalytical Chemistry 401 3 (2011): 983-993. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052581487&partnerID=MN8TOARS.
    10.1007/s00216-011-5124-y
  200. Barroso, M.; Costa, S.; Dias, M.; Vieira, D.N.; Queiroz, J.A.; López-Rivadulla, M.. "Analysis of phenylpiperazine-like stimulants in human hair as trimethylsilyl derivatives by gas chromatography-mass spectrometry". Journal of Chromatography A 1217 40 (2010): 6274-6280. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956651160&partnerID=MN8TOARS.
    10.1016/j.chroma.2010.08.001
  201. Sousa, F.; Cruz, C.; Queiroz, J.A.. "Amino acids-nucleotides biomolecular recognition: From biological occurrence to affinity chromatography". Journal of Molecular Recognition 23 6 (2010): 505-518. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049440483&partnerID=MN8TOARS.
    10.1002/jmr.1053
  202. Martins, R.; Queiroz, J.A.; Sousa, F.. "A new affinity approach to isolate Escherichia coli 6S RNA with histidine-chromatography". Journal of Molecular Recognition 23 6 (2010): 519-524. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049417545&partnerID=MN8TOARS.
    10.1002/jmr.1078
  203. Silva, A.; Boto, R.E.F.; Tomaz, C.T.; Queiroz, J.A.; Almeida, P.. "Rhodamine B as ligand for affinity chromatography: Chromatographic studies on derivatized beaded cellulose". Journal of Chromatographic Science 48 3 (2010): 240-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949310368&partnerID=MN8TOARS.
    10.1093/chromsci/48.3.240
  204. Barroso, M.; Dias, M.; Vieira, D.N.; LóPez-Rivadulla, M.; Queiroz, J.A.. "Mixed-mode solid-phase extraction for sample cleanup in hair analysis for methadone and its main metabolite". Biomedical Chromatography 24 11 (2010): 1240-1246. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958485570&partnerID=MN8TOARS.
    10.1002/bmc.1434
  205. Gouveia, I.C.; Dias, L.P.; Fiadeiro, J.M.; Queiroz, J.A.. "Enzymatic Treatments to Improve the Dyeability of Linen Fabrics: Optimization and Empirical Modeling using Experimental Design Techniques". Textile Research Journal 80 15 (2010): 1602-1615. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956547719&partnerID=MN8TOARS.
    10.1177/0040517510363186
  206. Sousa, A.; Sousa, F.; Queiroz, J.A.. "Differential interactions of plasmid DNA, RNA and genomic DNA with amino acid-based affinity matrices". Journal of Separation Science 33 17-18 (2010): 2610-2618. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956918746&partnerID=MN8TOARS.
    10.1002/jssc.201000347
  207. Raposo, R.; Barroso, M.; Fonseca, S.; Costa, S.; Queiroz, J.A.; Gallardo, E.; Dias, M.. "Determination of eight selected organophosphorus insecticides in postmortem blood samples using solid-phase extraction and gas chromatography/mass spectrometry". Rapid Communications in Mass Spectrometry 24 21 (2010): 3187-3194. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649416760&partnerID=MN8TOARS.
    10.1002/rcm.4765
  208. Ferreira, S.; Gil, N.; Queiroz, J.A.; Duarte, A.P.; Domingues, F.C.. "Bioethanol from the Portuguese forest residue Pterospartum tridentatum - An evaluation of pretreatment strategy for enzymatic saccharification and sugars fermentation". Bioresource Technology 101 20 (2010): 7797-7803. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954309619&partnerID=MN8TOARS.
    10.1016/j.biortech.2010.05.038
  209. Nunes, V.S.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Assessment of COMT isolation by HIC using a dual salt system and low temperature". Biomedical Chromatography 24 8 (2010): 858-862. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954706256&partnerID=MN8TOARS.
    10.1002/bmc.1377
  210. Paulo, L.; Ferreira, S.; Gallardo, E.; Queiroz, J.A.; Domingues, F.. "Antimicrobial activity and effects of resveratrol on human pathogenic bacteria". World Journal of Microbiology and Biotechnology 26 8 (2010): 1533-1538. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954428278&partnerID=MN8TOARS.
    10.1007/s11274-010-0325-7
  211. Silva, F.; Lourenço, O.; Pina-Vaz, C.; Rodrigues, A.G.; Queiroz, J.A.; Domingues, F.C.. "The use of DRAQ5 to monitor intracellular DNA in escherichia coli by flow cytometry". Journal of Fluorescence 20 4 (2010): 907-914. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955656727&partnerID=MN8TOARS.
    10.1007/s10895-010-0636-y
  212. Barroso, M.; Dias, M.; Vieira, D.N.; López-Rivadulla, M.; Queiroz, J.A.. "Simultaneous quantitation of morphine, 6-acetylmorphine, codeine, 6-acetylcodeine and tramadol in hair using mixed-mode solid-phase extraction and gas chromatography-mass spectrometry". Analytical and Bioanalytical Chemistry 396 8 (2010): 3059-3069. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951216190&partnerID=MN8TOARS.
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  213. Palmeira-De-Oliveira, A.; Ribeiro, M.P.; Palmeira-De-Oliveira, R.; Gaspar, C.; Costa-De-Oliveira, S.; Correia, I.J.; Pina Vaz, C.; et al. "Anti-Candida activity of a chitosan hydrogel: Mechanism of action and cytotoxicity profile". Gynecologic and Obstetric Investigation 70 4 (2010): 322-327. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649688221&partnerID=MN8TOARS.
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  214. Boto, R.E.F.; Anyanwu, U.; Sousa, F.; Almeida, P.; Queiroz, J.A.. "Thiacarbocyanine as ligand in dye-affinity chromatography for protein purification. II. Dynamic binding capacity using lysozyme as a model". Biomedical Chromatography 23 9 (2009): 987-993. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349478902&partnerID=MN8TOARS.
    10.1002/bmc.1212
  215. Sousa, Â.; Sousa, F.; Queiroz, J.A.. "Selectivity of arginine chromatography in promoting different interactions using synthetic oligonucleotides as model". Journal of Separation Science 32 10 (2009): 1665-1672. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650001336&partnerID=MN8TOARS.
    10.1002/jssc.200800690
  216. Ferreira, S.; Duarte, A.P.; Ribeiro, M.H.L.; Queiroz, J.A.; Domingues, F.C.. "Response surface optimization of enzymatic hydrolysis of Cistus ladanifer and Cytisus striatus for bioethanol production". Biochemical Engineering Journal 45 3 (2009): 192-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-66849128580&partnerID=MN8TOARS.
    10.1016/j.bej.2009.03.012
  217. Sousa, A.; Sousa, F.; Queiroz, J.A.. "Biorecognition of supercoiled plasmid DNA isoform in lysine-affinity chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 877 27 (2009): 3257-3260. http://www.scopus.com/inward/record.url?eid=2-s2.0-69749124060&partnerID=MN8TOARS.
    10.1016/j.jchromb.2009.08.021
  218. Sousa, F.; Passarinha, L.; Queiroz, J.A.. "Biomedical application of plasmid DNA in gene therapy: A new challenge for chromatography". Biotechnology and Genetic Engineering Reviews 26 1 (2009): 83-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-77749249237&partnerID=MN8TOARS.
    10.5661/bger-26-83
  219. Barroso, M.; Gallardo, E.; Queiroz, J.A.. "Bioanalytical methods for the determination of cocaine and metabolites in human biological samples". Bioanalysis 1 5 (2009): 977-1000. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958472582&partnerID=MN8TOARS.
    10.4155/bio.09.72
  220. Sousa, F.; Prazeres, D.M.F.; Queiroz, J.A.. "Binding and elution strategy for improved performance of arginine affinity chromatography in supercoiled plasmid DNA purification". Biomedical Chromatography 23 2 (2009): 160-165. http://www.scopus.com/inward/record.url?eid=2-s2.0-61349098946&partnerID=MN8TOARS.
    10.1002/bmc.1097
  221. Passarinha, L.A.; Bonifácio, M.J.; Queiroz, J.A.. "Application of a fed-batch bioprocess for the heterologous production of hSCOMT in Escherichia coli". Journal of Microbiology and Biotechnology 19 9 (2009): 972-981. http://www.scopus.com/inward/record.url?eid=2-s2.0-70849085440&partnerID=MN8TOARS.
    10.4014/jmb.0812.658
  222. Palmeira-de-Oliveira, A.; Salgueiro, L.; Palmeira-de-Oliveira, R.; Martinez-de-Oliveira, J.; Pina-Vaz, C.; Queiroz, J.A.; Rodrigues, A.G.. "Anti-Candida activity of essential oils". Mini-Reviews in Medicinal Chemistry 9 11 (2009): 1292-1305. http://www.scopus.com/inward/record.url?eid=2-s2.0-73349112212&partnerID=MN8TOARS.
    10.2174/138955709789878150
  223. Oudia, A.; Mészáros, E.; Jakab, E.; Simões, R.; Queiroz, J.; Ragauskas, A.; Novák, L.. "Analytical pyrolysis study of biodelignification of cloned Eucalyptus globulus (EG) clone and Pinus pinaster Aiton kraft pulp and residual lignins". Journal of Analytical and Applied Pyrolysis 85 1-2 (2009): 19-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349234966&partnerID=MN8TOARS.
    10.1016/j.jaap.2008.09.015
  224. Gallardo, E.; Barroso, M.; Queiroz, J.A.. "LC-MS: A powerful tool in workplace drug testing". Drug Testing and Analysis 1 3 (2009): 109-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951295305&partnerID=MN8TOARS.
    10.1002/dta.26
  225. Silva, F.; Passarinha, L.; Sousa, F.; Queiroz, J.A.; Domingues, F.C.. "Influence of growth conditions on plasmid DNA production". Journal of Microbiology and Biotechnology 19 11 (2009): 1408-1414. http://www.scopus.com/inward/record.url?eid=2-s2.0-71549136850&partnerID=MN8TOARS.
    10.4014/jmb.0805.0329
  226. Ferreira, S.M.P.; Duarte, A.P.; Queiroz, J.A.; Domingues, F.C.. "Influence of buffer systems on Trichoderma reesei Rut C-30 morphology and cellulase production". Electronic Journal of Biotechnology 12 3 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-67749142404&partnerID=MN8TOARS.
    10.2225/vol12-issue3-fulltext-6
  227. Sousa, F.; Prazeres, D.M.F.; Queiroz, J.A.. "Improvement of transfection efficiency by using supercoiled plasmid DNA purified with arginine affinity chromatography". Journal of Gene Medicine 11 1 (2009): 79-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-59449090459&partnerID=MN8TOARS.
    10.1002/jgm.1272
  228. Sousa, A.; Sousa, F.; Prazeres, D.M.F.; Queiroz, J.A.. "Histidine affinity chromatography of homo-oligonucleotides. Role of multiple interactions on retention". Biomedical Chromatography 23 7 (2009): 745-753. http://www.scopus.com/inward/record.url?eid=2-s2.0-69749128313&partnerID=MN8TOARS.
    10.1002/bmc.1179
  229. Morão, A.; Nunes, J.C.; Sousa, F.; Amorim, M.T.P.d.; Escobar, I.C.; Queiroz, J.A.. "Development of a model for membrane filtration of long and flexible macromolecules: Application to predict dextran and linear DNA rejections in ultrafiltration". Journal of Membrane Science 336 1-2 (2009): 61-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349194357&partnerID=MN8TOARS.
    10.1016/j.memsci.2009.03.007
  230. Gallardo, E.; Barroso, M.; Queiroz, J.A.. "Current technologies and considerations for drug bioanalysis in oral fluid". Bioanalysis 1 3 (2009): 637-667. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953000736&partnerID=MN8TOARS.
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  231. Boto, R.E.F.; Almeida, P.; Queiroz, J.A.. "Thiacarbocyanine as ligand in dye-affinity chromatography for protein purification". Biomedical Chromatography 22 3 (2008): 278-288. http://www.scopus.com/inward/record.url?eid=2-s2.0-41549154705&partnerID=MN8TOARS.
    10.1002/bmc.925
  232. Gouveia, I.C.; Fiadeiro, J.M.; Queiroz, J.A.. "Combined bio-carbonization and dyeing of wool: A possibility of using cell wall-degrading enzymes and 1:1 metal-complex dyes". Engineering in Life Sciences 8 3 (2008): 250-259. http://www.scopus.com/inward/record.url?eid=2-s2.0-48049095750&partnerID=MN8TOARS.
    10.1002/elsc.200700055
  233. Morão, A.; Pessoa de Amorim, M.T.; Lopes, A.; Escobar, I.; Queiroz, J.A.. "Characterisation of ultrafiltration and nanofiltration membranes from rejections of neutral reference solutes using a model of asymmetric pores". Journal of Membrane Science 319 1-2 (2008): 64-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-44249104910&partnerID=MN8TOARS.
    10.1016/j.memsci.2008.03.019
  234. Sousa, F.; Prazeres, D.M.F.; Queiroz, J.A.. "Affinity chromatography approaches to overcome the challenges of purifying plasmid DNA". Trends in Biotechnology 26 9 (2008): 518-525. http://www.scopus.com/inward/record.url?eid=2-s2.0-48849111296&partnerID=MN8TOARS.
    10.1016/j.tibtech.2008.05.005
  235. Passarinha, L.A.; Bonifácio, M.J.; Soares-da-Silva, P.; Queiroz, J.A.. "A new approach on the purification of recombinant human soluble catechol-O-methyltransferase from an Escherichia coli extract using hydrophobic interaction chromatography". Journal of Chromatography A 1177 2 (2008): 287-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-37449015254&partnerID=MN8TOARS.
    10.1016/j.chroma.2007.06.002
  236. Gallardo, E.; Queiroz, J.A.. "The role of alternative specimens in toxicological analysis". Biomedical Chromatography 22 8 (2008): 795-821. http://www.scopus.com/inward/record.url?eid=2-s2.0-50049102756&partnerID=MN8TOARS.
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  237. Oudia, A.; Queiroz, J.; Simões, R.. "The influence of operating parameters on the biodelignification of eucalyptus globulus kraft pulps in a laccase-violuric acid system". Applied Biochemistry and Biotechnology 149 1 (2008): 23-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-52049084436&partnerID=MN8TOARS.
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  238. Sousa, F.; Matos, T.; Prazeres, D.M.F.; Queiroz, J.A.. "Specific recognition of supercoiled plasmid DNA in arginine affinity chromatography". Analytical Biochemistry 374 2 (2008): 432-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-39149129979&partnerID=MN8TOARS.
    10.1016/j.ab.2007.11.005
  239. Sousa, A.; Passarinha, L.A.; Rodrigues, L.R.; Teixeira, J.A.; Mendonça, A.; Queiroz, J.A.. "Separation of different forms of proteose peptone 3 by hydrophobic interaction chromatography with a dual salt system". Biomedical Chromatography 22 5 (2008): 447-449. http://www.scopus.com/inward/record.url?eid=2-s2.0-44249099939&partnerID=MN8TOARS.
    10.1002/bmc.961
  240. Oudia, A.; Queiroz, J.; Simões, R.. "Potential and limitation of Trametes versicolor laccase on biodegradation of Eucalyptus globulus and Pinus pinaster kraft pulp". Enzyme and Microbial Technology 43 2 (2008): 144-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-44449169389&partnerID=MN8TOARS.
    10.1016/j.enzmictec.2007.11.016
  241. Gouveia, I.C.; Fiadeiro, J.M.; Queiroz, J.A.. "Enzymatic removal of plant residues from wool: Application of experimental design techniques for optimization parameters". Biochemical Engineering Journal 41 2 (2008): 157-165. http://www.scopus.com/inward/record.url?eid=2-s2.0-48049116891&partnerID=MN8TOARS.
    10.1016/j.bej.2008.04.008
  242. Barroso, M.; Dias, M.; Vieira, D.N.; Queiroz, J.A.; López-Rivadulla, M.. "Development and validation of an analytical method for the simultaneous determination of cocaine and its main metabolite, benzoylecgonine, in human hair by gas chromatography/mass spectrometry". Rapid Communications in Mass Spectrometry 22 20 (2008): 3320-3326. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149192806&partnerID=MN8TOARS.
    10.1002/rcm.3738
  243. Oudia, A.; Mészáros, E.; Simões, R.; Queiroz, J.; Jakab, E.. "Pyrolysis-GC/MS and TG/MS study of mediated laccase biodelignification of Eucalyptus globulus kraft pulp". Journal of Analytical and Applied Pyrolysis 78 2 (2007): 233-242. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846371212&partnerID=MN8TOARS.
    10.1016/j.jaap.2006.07.003
  244. Sousa, F.; Prazeres, D.M.F.; Queiroz, J.A.. "Dynamic binding capacity of plasmid DNA in histidine-agarose chromatography". Biomedical Chromatography 21 9 (2007): 993-998. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547966151&partnerID=MN8TOARS.
    10.1002/bmc.846
  245. Passarinha, L.A.; Bonifácio, M.J.; Queiroz, J.A.. "Comparative study on the interaction of recombinant human soluble catechol-O-methyltransferase on some hydrophobic adsorbents". Biomedical Chromatography 21 4 (2007): 430-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-34147168274&partnerID=MN8TOARS.
    10.1002/bmc.779
  246. Sousa, F.; Prazeres, D.M.F.; Queiroz, J.A.. "Circular dichroism investigation of the effect of plasmid DNA structure on retention in histidine chromatography". Archives of Biochemistry and Biophysics 467 2 (2007): 154-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748978569&partnerID=MN8TOARS.
    10.1016/j.abb.2007.08.027
  247. Passarinha, L.A.; Bonifcio, M.J.; Queiroz, J.A.. "The effect of temperature on the analysis of metanephrine for catechol-O-methyltransferase activity assay by HPLC with electrochemical detection". Biomedical Chromatography 20 9 (2006): 937-944. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748951956&partnerID=MN8TOARS.
    10.1002/bmc.623
  248. Sousa, F.; Freitas, S.; Azzoni, A.R.; Prazeres, D.M.F.; Queiroz, J.. "Selective purification of supercoiled plasmid DNA from clarified cell lysates with a single histidine-agarose chromatography step". Biotechnology and Applied Biochemistry 45 3 (2006): 131-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750607427&partnerID=MN8TOARS.
    10.1042/BA20060082
  249. Passarinha, L.A.; Diogo, M.M.; Queiroz, J.A.; Monteiro, G.A.; Fonseca, L.P.; Prazeres, D.M.F.. "Production of ColE1 type plasmid by Escherichia coli DH5a cultured under nonselective conditions". Journal of Microbiology and Biotechnology 16 1 (2006): 20-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-32944454986&partnerID=MN8TOARS.
  250. Sousa, F.; Ferreira, S.; Queiroz, J.; Domingues, F.. "Production of a fusion protein containing the antigenic domain 1 of human cytomegalovirus glycoprotein B". Journal of Microbiology and Biotechnology 16 7 (2006): 1026-1031. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746894082&partnerID=MN8TOARS.
  251. Sousa, F.; Melo, A.; Almeida, S.; Paixão, P.; Queiroz, J.A.; Domingues, F.C.. "Isolation of a fusion protein containing the antigenic domain 1 of human cytomegalovirus glycoprotein B and its application in ELISA tests". Biotechnology Letters 28 2 (2006): 73-77. http://www.scopus.com/inward/record.url?eid=2-s2.0-29244483677&partnerID=MN8TOARS.
    10.1007/s10529-005-4949-x
  252. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.F.. "Chromatography of plasmid DNA". Journal of Chromatography A 1069 1 (2005): 3-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-15244358693&partnerID=MN8TOARS.
    10.1016/j.chroma.2004.09.050
  253. Dias-Cabral, A.C.; Ferreira, A.S.; Phillips, J.; Queiroz, J.A.; Pinto, N.G.. "The effects of ligand chain length, salt concentration and temperature on the adsorption of bovine serum albumin onto polypropyleneglycol-Sepharose". Biomedical Chromatography 19 8 (2005): 606-616. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844510418&partnerID=MN8TOARS.
    10.1002/bmc.487
  254. Sousa, F.; Tomaz, C.T.; Prazeres, D.M.F.; Queiroz, J.A.. "Separation of supercoiled and open circular plasmid DNA isoforms by chromatography with a histidine-agarose support". Analytical Biochemistry 343 1 (2005): 183-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-22144443546&partnerID=MN8TOARS.
    10.1016/j.ab.2005.03.011
  255. Ferreira, S.; Sousa, F.; Queiroz, J.A.; Domingues, F.C.. "Improved recovery of a fusion protein containing the antigenic domain 1 of the human cytomegalovirus glycoprotein B". Biotechnology Letters 27 16 (2005): 1241-1245. http://www.scopus.com/inward/record.url?eid=2-s2.0-24744466678&partnerID=MN8TOARS.
    10.1007/s10529-005-0024-x
  256. Tomaz, C.T.; Queiroz, J.A.. "Fractionation of Trichoderma reesei cellulases by hydrophobic interaction chromatography on phenyl-Sepharose". Biotechnology Letters 26 3 (2004): 223-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342267389&partnerID=MN8TOARS.
    10.1023/B:BILE.0000013719.92024.04
  257. Diogo, M.M.; Prazeres, D.M.F.; Pinto, N.G.; Queiroz, J.A.. "Hydrophobic interaction chromatography of homo-oligonucleotides on derivatized Sepharose CL-6B: Using and relating two different models for describing the effect of salt and temperature on retention". Journal of Chromatography A 1006 1-2 (2003): 137-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042848639&partnerID=MN8TOARS.
    10.1016/S0021-9673(03)00918-X
  258. Dias-Cabral, A.C.; Queiroz, J.A.; Pinto, N.G.. "Effect of salts and temperature on the adsorption of bovine serum albumin on polypropylene glycol-Sepharose under linear and overloaded chromatographic conditions". Journal of Chromatography A 1018 2 (2003): 137-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642406342&partnerID=MN8TOARS.
    10.1016/j.chroma.2003.07.010
  259. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.F.. "Assessment of purity and quantification of plasmid DNA in process solutions using high-performance hydrophobic interaction chromatography". Journal of Chromatography A 998 1-2 (2003): 109-117. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038392599&partnerID=MN8TOARS.
    10.1016/S0021-9673(03)00618-6
  260. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.F.. "Hydrophobic interaction chromatography of homo-oligonucleotides on derivatized Sepharose CL-6B Application of the solvophobic theory". Journal of Chromatography A 944 1-2 (2002): 119-128. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037168964&partnerID=MN8TOARS.
    10.1016/S0021-9673(01)01388-7
  261. Tomaz, C.T.; Duarte, D.; Queiroz, J.A.. "Comparative study on the fractionation of cellulases on some hydrophobic interaction chromatography adsorbents". Journal of Chromatography A 944 1-2 (2002): 211-216. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037168965&partnerID=MN8TOARS.
    10.1016/S0021-9673(01)01224-9
  262. Dias-Cabral, A.C.; Pinto, N.G.; Queiroz, J.A.. "Studies on hydrophobic interaction adsorption of bovine serum albumin on polypropylene glycol-sepharose under overloaded conditions". Separation Science and Technology 37 7 (2002): 1505-1520. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036263590&partnerID=MN8TOARS.
    10.1081/SS-120002734
  263. Pardal, A.C.; Nunes, M.J.; Gama, A.M.; Queiroz, J.A.; Almeida, P.. "Preliminary studies on the use of cyanines as ligands in dye-affinity chromatography of proteins". Coloration Technology 118 3 (2002): 95-99. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036064053&partnerID=MN8TOARS.
    10.1111/j.1478-4408.2002.tb00363.x
  264. Tomaz, C.T.; Rocha, A.S.; Queiroz, J.A.. "Hydrophobic interaction chromatography of Trichoderma reesei cellulases on polypropylene glycol-sepharose". Separation Science and Technology 37 7 (2002): 1641-1651. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036266523&partnerID=MN8TOARS.
    10.1081/SS-120002741
  265. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.F.. "Studies on the retention of plasmid DNA and Escherichia coli nucleic acids by hydrophobic interaction chromatography". Bioseparation 10 4-5 (2001): 211-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035554023&partnerID=MN8TOARS.
    10.1023/A:1016361721316
  266. Diogo, M.M.; Ribeiro, S.C.; Queiroz, J.A.; Monteiro, G.A.; Tordo, N.; Perrin, P.; Prazeres, D.M.F.. "Production, purification and analysis of an experimental DNA vaccine against rabies". Journal of Gene Medicine 3 6 (2001): 577-584. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035523565&partnerID=MN8TOARS.
    10.1002/jgm.218
  267. Domingues, F.C.; Queiroz, J.A.; Cabral, J.M.S.; Fonseca, L.P.. "Production of cellulases in batch culture using a mutant strain of Trichoderma reesei growing on soluble carbon source". Biotechnology Letters 23 10 (2001): 771-775. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034985126&partnerID=MN8TOARS.
    10.1023/A:1010329731010
  268. Queiroz, J.A.; Tomaz, C.T.; Cabral, J.M.S.. "Hydrophobic interaction chromatography of proteins". Journal of Biotechnology 87 2 (2001): 143-159. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035805436&partnerID=MN8TOARS.
    10.1016/S0168-1656(01)00237-1
  269. Diogo, M.M.; Queiroz, J.A.; Monteiro, G.A.; Martins, S.A.M.; Ferreira, G.N.M.; Prazeres, D.M.F.. "Purification of a cystic fibrosis plasmid vector for gene therapy using hydrophobic interaction chromatography". Biotechnology and Bioengineering 68 5 (2000): 576-583. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034608587&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0290(20000605)68:5<576::AID-BIT13>3.0.CO;2-5
  270. Domingues, F.C.; Queiroz, J.A.; Cabral, J.M.S.; Fonseca, L.P.. "The influence of culture conditions on mycelial structure and cellulase production by Trichoderma reesei Rut C-30". Enzyme and Microbial Technology 26 5-6 (2000): 394-401. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034002738&partnerID=MN8TOARS.
    10.1016/S0141-0229(99)00166-0
  271. Diogo, M.M.; Ribeiro, S.; Queiroz, J.A.; Monteiro, G.A.; Perrin, P.; Tordo, N.; Prazeres, D.M.F.. "Scale-up of hydrophobic interaction chromatography for the purification of a DNA vaccine against rabies". Biotechnology Letters 22 17 (2000): 1397-1400. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033799808&partnerID=MN8TOARS.
    10.1023/A:1005665003375
  272. Esquibel-King, M.A.; Dias-Cabral, A.C.; Queiroz, J.A.; Pinto, N.G.. "Study of hydrophobic interaction adsorption of bovine serum albumin under overloaded conditions using flow microcalorimetry". Journal of Chromatography A 865 1-2 (1999): 111-122. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032749304&partnerID=MN8TOARS.
    10.1016/S0021-9673(99)01118-8
  273. Tomaz, C.T.; Queiroz, J.A.. "Studies on the chromatographic fractionation of Trichoderma reesei cellulases by hydrophobic interaction". Journal of Chromatography A 865 1-2 (1999): 123-128. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032735213&partnerID=MN8TOARS.
    10.1016/S0021-9673(99)00851-1
  274. Diogo, M.M.; Queiroz, J.A.; Monteiro, G.A.; Prazeres, D.M.F.. "Separation and analysis of plasmid denatured forms using hydrophobic interaction chromatography". Analytical Biochemistry 275 1 (1999): 122-124. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033231382&partnerID=MN8TOARS.
    10.1006/abio.1999.4297
  275. Cascalheira, J.F.; Queiroz, J.A.. "Kinetic study of the cellobiase activity of Trichoderma reesei cellulase complex at high substrate concentrations". Biotechnology Letters 21 8 (1999): 651-655. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032854876&partnerID=MN8TOARS.
    10.1023/A:1005525015777
  276. Diogo, M.M.; Silva, S.; Cabral, J.M.S.; Queiroz, J.A.. "Hydrophobic interaction chromatography of Chromobacterium viscosum lipase on polypropylene glycol immobilised on Sepharose". Journal of Chromatography A 849 2 (1999): 413-419. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033062863&partnerID=MN8TOARS.
    10.1016/S0021-9673(99)00619-6
  277. Diogo, M.M.; Cabral, J.M.S.; Queiroz, J.A.. "Preliminary study on hydrophobic interaction chromatography of Chromobacterium viscosum lipase on polypropylene glycol immobilized on Sepharose". Journal of Chromatography A 796 1 (1998): 177-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032512744&partnerID=MN8TOARS.
    10.1016/S0021-9673(97)01059-5
  278. Queiroz, J.A.; Garcia, F.A.P.; Cabral, J.M.S.. "Hydrophobic interaction chromatography of Chromobacterium viscosum lipase on polyethylene glycol immobilized on Sepharose". Journal of Chromatography A 734 1 (1996): 213-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029933936&partnerID=MN8TOARS.
    10.1016/0021-9673(95)01163-3
  279. Queiroz, J.A.; Garcia, F.A.P.; Cabral, J.M.S.. "Hydrophobic interaction chromatography of Chromobacterium viscosum lipase". Journal of Chromatography A 707 2 (1995): 137-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029148070&partnerID=MN8TOARS.
    10.1016/0021-9673(95)00134-9

Other

Other output
  1. Enzymatic wool treatment: Preliminary evaluation of Trichoderma reesei cellulases and aspergillus aculeatus pectinases and hemicellulases. 2008. Gouveia, I.C.; Fiadeiro, J.M.; Queiroz, J.A.. http://www.scopus.com/inward/record.url?eid=2-s2.0-56449114975&partnerID=MN8TOARS.