???global.info.a_carregar???
Carla Cristina Marques de Oliveira. Completed the Doutoramento in PhD in Chemical and Biological Engineering in 2009/12/15 by Universidade do Minho Escola de Engenharia, Mestrado in Mestrado em Biotecnologia - Engenharia de Bioprocessos in 2005 by Universidade do Minho Escola de Engenharia and Licenciatura in Licenciatura em Engenharia Biológica in 2001 by Universidade do Minho Escola de Engenharia. Is Auxiliary Researcher in Universidade Católica Portuguesa Escola Superior de Biotecnologia. Published 35 articles in journals. Has 7 section(s) of books and 2 book(s). Organized 2 event(s). Participated in 3 event(s). Supervised 2 PhD thesis(es). Supervised 5 MSc dissertation(s) e co-supervised 8. Has received 2 awards and/or honors. Participates and/or participated as Other in 5 project(s), Post-doc in 2 project(s) and Principal investigator in 1 project(s). Works in the area(s) of Engineering and Technology with emphasis on Industrial Biotechnology with emphasis on Fermentation and Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology. In their professional activities interacted with 190 collaborator(s) co-authorship of scientific papers.
Read full resume ↓
Identification

Personal identification

Full name
Carla Cristina Marques de Oliveira

Citation names

  • Oliveira, Carla
  • Oliveira C.

Author identifiers

Ciência ID
9118-9E0D-2CBE
ORCID iD
0000-0001-5006-3008
Researcher Id
O-6563-2015
Scopus Author Id
55972889000

Email addresses

  • carlamoliveira@gmail.com (Personal)

Websites

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology - Fermentation
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2005/03/01 - 2009/12/15
Concluded
 PhD in Chemical and Biological Engineering (Doutoramento)
Universidade do Minho Escola de Engenharia, Portugal
"Expression and production of recombinant frutalin in different expression systems and evaluation of its biomedical applications" (THESIS/DISSERTATION)
 Approved by unanimity
2005
Concluded
 Mestrado em Biotecnologia - Engenharia de Bioprocessos (Mestrado)
Universidade do Minho Escola de Engenharia, Portugal
"Produção de beta-galactosidase por levedura recombinante – Desenvolvimento de um sistema de produção estável" (THESIS/DISSERTATION)
 Muito Bom
2003
Concluded
 Curso de Especialização em Biotecnologia - Engenharia de Bioprocessos (Especialização pós-licenciatura)
Universidade do Minho Escola de Engenharia, Portugal
 17
2001
Concluded
 Licenciatura em Engenharia Biológica (Licenciatura)
Universidade do Minho Escola de Engenharia, Portugal
"(não aplicável)" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2023/11/01 - Current Auxiliary Researcher (Research) BIORBIS - UNIPESSOAL LDA (BIORBIS), Portugal
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2019/05/20 - 2023/09/30 Auxiliary Researcher (Research) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2018/12/07 - 2019/05/19 Contracted Researcher (Research) Universidade do Minho Centro de Engenharia Biológica, Portugal
Universidade do Minho, Portugal
2010/03/01 - 2018/12/06 Postdoc (Research) Universidade do Minho Centro de Engenharia Biológica, Portugal
Universidade do Minho Centro de Engenharia Biológica, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2013/09/01 - 2014/03/30 Invited Assistant Professor (University Teacher) Universidade do Minho, Portugal
Universidade do Minho, Portugal
2010/10/01 - 2011/09/30 Invited Assistant Professor (University Teacher) Universidade do Minho, Portugal
Universidade do Minho, Portugal
Projects

Grant

Designation Funders
2016 - 2019 SFRH/BPD/110640/2015 - Novel peptide-based technology for mycotoxins determination from food
SFRH/BPD/110640/2015
Post-doc
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010 - 2016 SFRH/BPD/63831/2009 - Improving the properties of paper and textile fibers using recombinant glycosylated CBMs
SFRH/BPD/63831/2009
Post-doc
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded

Contract

Designation Funders
2019/05/20 - 2023/09/30 Alchemy - Capturing High Value from Industrial Fermentation BioProduct
POCI-01-0247-FEDER-027578
Assistant Researcher
Concluded
2018 - 2019 EcoBioInks - Photocontrolable, reversibly photoswitchable and eco-sustainable fluorescent bio-inks for smart textile fabrication
PTDC/CTM-TEX/30298/2017
Team member
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2017 - 2019 BBRI - Biomass and Bioenergy Research Infrastructure
01/SAICT/2016
Team member
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluded
2016 - 2019 ACTONP53 - Targeting p53 family proteins: on the route to new anticancer agents
PTDC/DTP-FTO/1981/2014
Team member
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2016 - 2019 YeastTempTation - Tailoring thermotolerant yeasts for more sustainable, eco-efficient and competitive industrial fermentations
ERA-IB-2-6/0001/2014
Team member
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluded
2013/07 - 2015/06 GlycoCBMs - Fiber modification using recombinant glycosylated cellulose-binding modules
129208
Provided by PTCRIS: 129208
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2009 - 2010 Caracterização microbiológica de produtos cirúrgicos e das áreas de produção deste tipo de dispositivo, para avaliação do impacto nos métodos de produção e produtividades
Unknown
Research Fellow
Universidade do Minho, Portugal
Concluded
2003 - 2004 ZIMLAC - Produção de enZIMAS para a indústria alimentar por fermentação da LACtose do soro de queijo
Unknown
Research Fellow
Universidade do Minho, Portugal
 Agência Nacional de Inovação SA

Other

Designation Funders
2023/11/01 - Current Circulas - Joint Collaboration between Univ. Católica and Biorbis Company
Private funding
Assistant Researcher
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
Ongoing
Outputs

Publications

Book
  1. Oliveira C.; Martins Ivone; Santos Sílvio B.; Silva Sónia; Aguiar Tatiana Q. Book of the 2nd Proteome 2 Gene 2 Protein (P2G2P) Hands-On Course. Braga, Portugal. 2018.
    Published
  2. Oliveira C.; Martins Ivone; Santos Sílvio B.; Silva Sónia; Aguiar Tatiana Q. Book of the 1st Proteome 2 Gene 2 Protein (P2G2P) Hands-On Course. Braga, Portugal. 2016.
    Published
Book chapter
  1. Aguiar, Tatiana Q.; Oliveira, Carla; Domingues, Lucília. "Megaprimer-Based PCR to Synthesize Fusion Genes for Cloning". In Methods in Molecular Biology, 193-207. Springer US, 2023.
    10.1007/978-1-0716-3358-8_16
  2. Lígia Pimentel; Erdem Carsanba; Francisca Teixeira; Susana Vidigal; Manuela Pintado; Carla Oliveira; Luis M. Rodríguez-Alcalá. "Microbial Production of Terpenes". 2022.
    10.1007/978-3-030-81403-8_2-1
  3. Aguiar, Tatiana Q.; Santos, Sílvio B.; Martins, Ivone M.; Domingues, Lucília; Oliveira, Carla. "Production and Bioengineering of Recombinant Pharmaceuticals". In Proteins: Sustainable Source, Processing and Applications, 259-293. Elsevier, 2019.
    10.1016/b978-0-12-816695-6.00009-x
  4. Aguiar, T.Q.; Oliveira, C.; Domingues, L.. "Synthesis of fusion genes for cloning by megaprimer-based PCR". In PCR. Springer, 2017.
    Published • 10.1007/978-1-4939-7060-5_6
  5. Oliveira, C.; Aguiar, T.Q.; Domingues, L.. "Principles of Genetic Engineering". In Current Developments in Biotechnology and Bioengineering. 2016.
    Published • 10.1016/B978-0-444-63668-3.00004-4
  6. Oliveira, C.; Dragone, G.; Domingues, L.; Teixeira, J.A.. "Cheese whey fermentation". In Fermented Milk and Dairy Products, 427-458. Boca Raton: CRC Press, 2015.
    Published
  7. Oliveira, C.; Domingues, L.; Rodrigues, L.; Teixeira, J.A.. "Dairy". In Engineering Aspects of Food Biotechnology, 295-315. Boca Raton: CRC Press, 2013.
    Published
Conference abstract
  1. Oliveira C.; Teixeira JA; Lima N; Domingues L. "Stable production of Aspergillus niger beta-galactosidase by delta-mediated chromosomal integration in flocculent Saccharomyces cerevisiae". Paper presented in XXIInd International Conference on Yeast Genetics and Molecular Biology, Bratislava, 2005.
    Published
Conference poster
  1. Rodrigues DG; Adalsteinsson H; Pinto L; Aguiar TQ; Oliveira C.; Abrunhosa L; Domingues L. "Toward cost-effective production of recombinant human serum albumin for use in mycotoxin capture devices". Paper presented in Microbiotec23 - Portuguese Congress of Microbiology and Biotechnology, 2023.
  2. Aguiar TQ; Leal T; Rodrigues DG; Abrunhosa L; Oliveira C.; Domingues L. "Evaluation of ochratoxin A (OTA) interaction with recombinant domain II of bovine serum albumin toward the development of new OTA extraction platforms". Paper presented in Microbiotec23 - Portuguese Congress of Microbiology and Biotechnology, 2023.
  3. Lopes A; Carsanba E; Azevedo-Silva, João; Maria Manuela Estevez Pintado; Oliveira AS; Ferreira C; Pereira JO; Carvalho AP; Oliveira C.. "Improving oxidative stress tolerance of Saccharomyces cerevisiae using bioactive peptide extract from industrial spent yeast". Paper presented in PYFF8 - 8th Conference on Physiology of Yeasts and Filamentous Fungi, 2023.
  4. Carvalho LC; Oliveira ALS; Carsanba E; Pintado M; Oliveira C.. "Modulation of polyphenols in beta-farnesene fed-batch fermentation". Paper presented in 3rd BioIberoAmerica - IBERO-AMERICAN CONGRESS ON BIOTECHNOLOGY, 2022.
  5. Carvalho LC; Oliveira ALS; Carsanba E; Oliveira C.. "Phenolic compound modulation in yeast fed-batch fermentation using sugarcane syrup as feedstock". Paper presented in Microbiotec21 – Portuguese Congress of Microbiology and Biotechnology, 2021.
  6. Carvalho LC; Oliveira ALS; Carsanba E; Pintado M; Oliveira C.. "Detoxification of phenols in sugarcane syrup for improved yeast fermentation". Paper presented in Ciência 2021 - Encontro com a Ciência e Tecnologia em Portugal, 2021.
  7. Baptista LS; Oliveira C.; Romaní A; Domingues, L.. "The L-arabinose isomerase from the food grade Bacillus subtilis for the production of tagatose: a natural sweetener". Paper presented in MICROBIOTEC19 - Portuguese Congress of Microbiology and Biotechnology, 2019.
  8. Baptista M; Oliveira C.; Domingues, L.; Aguiar, Tatiana Q.. "Novel enzymes for the analysis and glycoengineering of therapeutic glycoproteins". Paper presented in 4th Meeting of Medicinal Biotechnology, 2019.
  9. Oliveira C.; Domingues, L.. "Quality control of recombinant proteins: from molecular design to application". Paper presented in RPP10 - 10th Conference on Recombinant Protein Production, 2019.
  10. Aguiar TQ; Silva Rui; Oliveira C.; Domingues, L.. "Substrate inhibition of Uracil Phosphoribosyltransferase (UPRT) in distinct microbial species and its implications in the phenotype of uracil auxotrophs". Paper presented in MICROBIOTEC17 - Portuguese Congress of Microbiology and Biotechnology,, 2017.
  11. Gomes AS; Gomes Sara; Soares J; Ramos H; Oliveira C.; Freire F; Pinheiro B; Marcelo F. "Uncovering the binding of the anticancer small molecule SLMP53-1 to mutant p53R280K". Paper presented in SPF 2017 - XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXV Reunião de Farmacologia Clínica, XVI Reunião de Toxicologia, 2017.
  12. Bourbon AI; Pinheiro AC; Oliveira C.; Domingues L; Rocha C; Cerqueira MA; Vicente AA. "Influence of a chitosan coating on protein-based nanohydrogels properties and in vitro digestibility". Paper presented in ICEF12 - 12th International Congress on Engineering and Food, 2015.
  13. Oliveira C.; Sepúlveda G; Aguiar TQ; Gama FM; Domingues L. "Elucidating the impact of N-glycosylation on the ability of recombinant CBM3 from Clostridium thermocellum to modify pulp and paper properties". Paper presented in CBM11 - 11th Carbohydrate Bioengineering Meeting, 2015.
  14. Oliveira C.; Sepúlveda G; Gama FM; Domingues L. "Improving paper properties using Clostridium thermocellum CBM3 glycosylated by Pichia pastoris". Paper presented in RPP8 - 8th Conference on Recombinant Protein Production, 2015.
  15. Oliveira C.; Sepúlveda MG; Costa SJ; Gama FM; Domingues L. "Cloning and expression of Clostridium thermocellum CBM3 in Pichia pastoris". Paper presented in MICROBIOTEC13 - Portuguese Congress of Microbiology and Biotechnology, 2013.
  16. Marlene L; Oliveira C.; Domingues L; Mota M; Belo I. "Expression of heterologous proteins by Pichia pastoris under increased air pressure". Paper presented in MICROBIOTEC13 - Portuguese Congress of Microbiology and Biotechnology, 2013.
  17. Magalhães F; Dinis C; Aguiar TQ; Oliveira C.; Domingues L. "High expression levels of Aspergillus niger beta-galactosidase in Ashbya gossypii". Paper presented in PYFF5: 5th Conference on Physiology of Yeast and Filamentous Fungi, 2013.
  18. Lima AS; Oliveira C.; Domingues L; Trindade H. "Isolation and molecular cloning of gamma-terpinene synthase gene from Thymus caespititius". Paper presented in MICROBIOTEC11 - Portuguese Congress of Microbiology and Biotechnology, 2011.
  19. Wanderley MSO; Oliveira C.; Mussatto SI; Bruneska D; Lima Filho JL; Domingues L; Teixeira JA. "Fed-batch fermentation for heterologous protein production by recombinant Pichia pastoris". Paper presented in BioMicroWorld 2009 - 3rd International Conference on Environmental, Industrial and Applied Microbiology (Fostering Cross-Disciplinary Applied Research in Microbiology and Microbial Biotechnology), 2009.
  20. Oliveira C.; Peixoto J; Teixeira JA; Domingues L. "Evaluation of the potential application of recombinant frutalin in cancer therapeutics". Paper presented in MICROBIOTEC9 - Portuguese Congress of Microbiology and Biotechnology, 2009.
  21. Wanderley MSO; Oliveira C.; Mussatto SI; Bruneska D; Lima Filho JL; Domingues L; Teixeira JA. "Influence of pH on cellular growth of Pichia pastoris KM71H by fed-batch process". Paper presented in MICROBIOTEC9 – Portuguese Congress of Microbiology and Biotechnology, 2009.
  22. Oliveira C.; Teixeira JA; Schmitt F; Domingues L. "Recombinant frutalin production and its potential application in cancer diagnosis and therapeutics". Paper presented in 1st Meeting of the Institute for Biotechnology and Bioengineering, 2009.
  23. Oliveira C.; Felix W; Costa SM; Avides MC; Moreira RA; Teixeira JA; Domingues L. "Cloning and expression of frutalin, an alpha-D-galactose binding lectin, in Pichia pastoris, Escherichia coli and baculovirus/insect cells system". Paper presented in RPP2008: 5th EFB Meeting on Recombinant Protein Production, 2008.
  24. Oliveira C.; Costa SM; Teixeira JA; Domingues L. "Production and purification of frutalin, a potential cancer marker, in Escherichia coli". Paper presented in ChemPor2008: 10th International Chemical and Biological Engineering Conference, 2008.
  25. Oliveira C.; Duarte M; Felix W; Moreira RA; Teixeira JA; Schmitt F; Domingues L. "Expression of frutalin in Pichia pastoris and evaluation of its potential as a cancer marker". Paper presented in MICROBIOTEC7 - Portuguese Congress of Microbiology and Biotechnology, 2007.
  26. Oliveira C.; Felix W; Moreira RA; Teixeira JA; Domingues L. "Cloning and expression of frutalin, an alpha-D-galactose-binding plant lectin, in Pichia pastoris". Paper presented in PYFF3: 3rd European Federation of Biotechnology Conference on Physiology of Yeasts and Filamentous Fungi, 2007.
  27. Félix WP; Nepomuceno DR; Oliveira C.; Teixeira JA; Domingues L; Costa JH; Grangeiro TB; Carvalho CPS; Moreira RA. "Production and characterization of recombinant frutalin expressed in the yeast Pichia pastoris". Paper presented in XXXVI Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (SBBq), 2007.
  28. Oliveira C.; Teixeira JA; Lima N; Domingues L. "Stable production of Aspergillus niger beta-galactosidase by delta-mediated chromosomal integration in flocculent Saccharomyces cerevisiae". Paper presented in XXIInd International Conference on Yeast Genetics and Molecular Biology, 2005.
  29. Oliveira C.; Teixeira JA; Lima N; Domingues L. "Delta multicopy integration for improved beta-galactosidase production in recombinant Saccharomyces cerevisiae". Paper presented in 3rd Recombinant Protein Production Meeting – A comparative view on host physiology, 2004.
Journal article
  1. Aguiar, Tatiana Q.; Leal, Tânia; Rodrigues, Diana G.; Abrunhosa, Luís; Oliveira, Carla; Domingues, Lucília. "Recombinant bovine serum albumin domain II as bioreceptor for ochratoxin A capture". Talanta 283 (2025): 127126. http://dx.doi.org/10.1016/j.talanta.2024.127126.
    10.1016/j.talanta.2024.127126
  2. Carvalho, Luís Carlos; Oliveira, Ana L. S.; Carsanba, Erdem; Lopes, Ana; Leal, Tânia; Ribeiro, Mónica; Fernandes, Sara; Pintado, Manuela; Oliveira, Carla. "Removal of phenolic compounds from sugarcane syrup and impact on Saccharomyces cerevisiae fermentation for ß-farnesene production". Biotechnology Journal 19 2 (2024): http://dx.doi.org/10.1002/biot.202300465.
    10.1002/biot.202300465
  3. Marco Duarte; Maria João Carvalho; Nelson Mota de Carvalho; João Azevedo-Silva; Adélia Mendes; Inês Pinto Ribeiro; João Carlos Fernandes; et al. "Skincare potential of a sustainable postbiotic extract produced through sugarcane straw fermentation by Saccharomyces cerevisiae". BioFactors (2023): http://dx.doi.org/10.1002/biof.1975.
    10.1002/biof.1975
  4. Ana Lopes; João Azevedo-Silva; Erdem Carsanba; Manuela Pintado; Ana Sofia Oliveira; Carlos Ferreira; Joana Odila Pereira; Ana P. Carvalho; Carla Oliveira. "Peptide extract from spent yeast improves resistance of Saccharomyces cerevisiae to oxidative stress". Applied Microbiology and Biotechnology (2023): https://doi.org/10.1007/s00253-023-12514-3.
    10.1007/s00253-023-12514-3
  5. Ana Lúcia Silva Oliveira; Marta Seara; Maria João Carvalho; Nelson Mota de Carvalho; Eduardo Costa; Sara Silva; Marco Duarte; et al. "Production of Sustainable Postbiotics from Sugarcane Straw for Potential Food Applications". Applied Sciences (2023): http://dx.doi.org/10.3390/app13063391.
    10.3390/app13063391
  6. Carvalho, Luís Carlos; Oliveira, Ana L.S.; Carsanba, Erdem; Pintado, Manuela; Oliveira, Carla. "Phenolic compounds modulation in ß-farnesene fed-batch fermentation using sugarcane syrup as feedstock". Industrial Crops and Products 188 (2022): 115721. http://dx.doi.org/10.1016/j.indcrop.2022.115721.
    10.1016/j.indcrop.2022.115721
  7. Duarte, Marco; Oliveira, Ana L.; Oliveira, Carla; Pintado, Manuela; Amaro, Ana; Madureira, Ana Raquel. "Current postbiotics in the cosmetic market - an update and development opportunities". Applied Microbiology and Biotechnology 106 18 (2022): 5879-5891. http://dx.doi.org/10.1007/s00253-022-12116-5.
    10.1007/s00253-022-12116-5
  8. Sara L. Baptista; Aloia Romaní; Carla Oliveira; Sara Ferreira; Cristina M.R. Rocha; Lucília Domingues. "Galactose to tagatose isomerization by the l-arabinose isomerase from Bacillus subtilis: A biorefinery approach for Gelidium sesquipedale valorisation". LWT (2021): https://doi.org/10.1016/j.lwt.2021.112199.
    10.1016/j.lwt.2021.112199
  9. Oliveira, Carla; Freitas, Ana Isabel; Campos, Nair; Saraiva, Lucília; Domingues, Lucília. "Cytotoxicity of Frutalin on Distinct Cancer Cells Is Independent of Its Glycosylation". Molecules 26 16 (2021): 4712. http://dx.doi.org/10.3390/molecules26164712.
    10.3390/molecules26164712
  10. Carsanba, Erdem; Pintado, Manuela; Oliveira, Carla. "Fermentation Strategies for Production of Pharmaceutical Terpenoids in Engineered Yeast". Pharmaceuticals 14 4 (2021): 295. http://dx.doi.org/10.3390/ph14040295.
    10.3390/ph14040295
  11. Gomes, Ana Sara; Ramos, Helena; Gomes, Sara; Loureiro, Joana B.; Soares, Joana; Barcherini, Valentina; Monti, Paola; et al. "SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations". Biochimica et Biophysica Acta (BBA) - General Subjects 1864 1 (2020): 129440. http://dx.doi.org/10.1016/j.bbagen.2019.129440.
    10.1016/j.bbagen.2019.129440
  12. Gomes, Sara; Bosco, Bartolomeo; Loureiro, Joana B.; Ramos, Helena; Raimundo, Liliana; Soares, Joana; Nazareth, Nair; et al. "SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma". Cancers 11 8 (2019): 1151. http://dx.doi.org/10.3390/cancers11081151.
    10.3390/cancers11081151
  13. Tânia Leal; Luís Abrunhosa; Lucília Domingues; Armando Venâncio; Carla Oliveira. "BSA-based sample clean-up columns for ochratoxin A determination in wine: method development and validation". Food Chemistry (2019): 125204-125204. https://doi.org/10.1016/j.foodchem.2019.125204.
    10.1016/j.foodchem.2019.125204
  14. Rui Silva; Tatiana Q. Aguiar; Carla Oliveira; Lucília Domingues. "Physiological characterization of a pyrimidine auxotroph exposes link between uracil phosphoribosyltransferase regulation and riboflavin production in Ashbya gossypii". New Biotechnology 50 (2019): 1-8. https://doi.org/10.1016/j.nbt.2018.12.004.
    10.1016/j.nbt.2018.12.004
  15. Carla Oliveira; Aloia Romaní; Daniel Gomes; Joana T. Cunha; Francisco M. Gama; Lucília Domingues. "Recombinant family 3 carbohydrate-binding module as a new additive for enhanced enzymatic saccharification of whole slurry from autohydrolyzed Eucalyptus globulus wood". Cellulose 25 4 (2018): 2505-2514. https://doi.org/10.1007/s10570-018-1722-6.
    10.1007/s10570-018-1722-6
  16. Gomes, A.S.; Trovão, F.; Andrade Pinheiro, B.; Freire, F.; Gomes, S.; Oliveira, C.; Domingues, L.; et al. "The crystal structure of the R280K mutant of human p53 explains the loss of DNA binding". International Journal of Molecular Sciences 19 4 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85045428921&partnerID=MN8TOARS.
    10.3390/ijms19041184
  17. Oliveira, C.; Domingues, L.. "Guidelines to reach high-quality purified recombinant proteins". Applied Microbiology and Biotechnology (2017): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034266794&partnerID=MN8TOARS.
    10.1007/s00253-017-8623-8
  18. Costa, V.L.D.; Costa, A.P.; Amaral, M.E.; Oliveira, C.; Gama, M.; Dourado, F.; Simões, R.M.. "Effect of hot calendering on physical properties and water vapor transfer resistance of bacterial cellulose films". Journal of Materials Science 51 21 (2016): 9562-9572. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979966740&partnerID=MN8TOARS.
    10.1007/s10853-016-0112-4
  19. Oliveira, H.; Pinto, G.; Oliveira, A.; Oliveira, C.; Faustino, M.A.; Briers, Y.; Domingues, L.; Azeredo, J.. "Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates". Applied Microbiology and Biotechnology 100 24 (2016): 10543-10553. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988927829&partnerID=MN8TOARS.
    10.1007/s00253-016-7858-0
  20. Oliveira, C.; Carvalho, V.; Domingues, L.; Gama, F.M.. "Recombinant CBM-fusion technology - Applications overview". Biotechnology Advances 33 3-4 (2015): 358-369. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929511557&partnerID=MN8TOARS.
    10.1016/j.biotechadv.2015.02.006
  21. Cunha, J.T.; Aguiar, T.Q.; Romaní, A.; Oliveira, C.; Domingues, L.. "Contribution of PRS3, RPB4 and ZWF1 to the resistance of industrial Saccharomyces cerevisiae CCUG53310 and PE-2 strains to lignocellulosic hydrolysate-derived inhibitors". Bioresource Technology 191 (2015): 7-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929095780&partnerID=MN8TOARS.
    10.1016/j.biortech.2015.05.006
  22. Oliveira, C.; Sepúlveda, G.; Aguiar, T.Q.; Gama, F.M.; Domingues, L.. "Modification of paper properties using carbohydrate-binding module 3 from the Clostridium thermocellum CipA scaffolding protein produced in Pichia pastoris: elucidation of the glycosylation effect". Cellulose 22 4 (2015): 2755-2765. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937972080&partnerID=MN8TOARS.
    10.1007/s10570-015-0655-6
  23. Lopes, M.; Oliveira, C.; Domingues, L.; Mota, M.; Belo, I.. "Enhanced heterologous protein production in Pichia pastoris under increased air pressure". Biotechnology Progress 30 5 (2014): 1040-1047. http://www.scopus.com/inward/record.url?eid=2-s2.0-84914105339&partnerID=MN8TOARS.
    10.1002/btpr.1964
  24. Magalhães, F.; Aguiar, T.Q.; Oliveira, C.; Domingues, L.. "High-level expression of Aspergillus niger ß-galactosidase in Ashbya gossypii". Biotechnology Progress 30 2 (2014): 261-268. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898544401&partnerID=MN8TOARS.
    10.1002/btpr.1844
  25. Aguiar, T.Q.; Dinis, C.; Magalhães, F.; Oliveira, C.; Wiebe, M.G.; Penttilä, M.; Domingues, L.. "Molecular and functional characterization of an invertase secreted by Ashbya gossypii". Molecular Biotechnology 56 6 (2014): 524-534. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900813550&partnerID=MN8TOARS.
    10.1007/s12033-013-9726-9
  26. Oliveira, C.; Teixeira, J.A.; Domingues, L.. "Recombinant production of plant lectins in microbial systems for biomedical application - The frutalin case study". Frontiers in Plant Science 5 AUG (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84907312208&partnerID=MN8TOARS.
    10.3389/fpls.2014.00390
  27. Wanderley, M.S.O.; Oliveira, C.; Bruneska, D.; Domingues, L.; Lima Filho, J.L.; Teixeira, J.A.; Mussatto, S.I.. "Influence of trace elements supplementation on the production of recombinant frutalin by Pichia pastoris KM71H in fed-batch process". Chemical Papers 67 7 (2013): 682-687. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879693274&partnerID=MN8TOARS.
    10.2478/s11696-013-0363-3
  28. Oliveira, C.; Teixeira, J.A.; Domingues, L.. "Recombinant lectins: An array of tailor-made glycan-interaction biosynthetic tools". Critical Reviews in Biotechnology 33 1 (2013): 66-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873112297&partnerID=MN8TOARS.
    10.3109/07388551.2012.670614
  29. Castro, I.; Oliveira, C.; Domingues, L.; Teixeira, J.A.; Vicente, A.A.. "The Effect of the Electric Field on Lag Phase, ß-Galactosidase Production and Plasmid Stability of a Recombinant Saccharomyces cerevisiae Strain Growing on Lactose". Food and Bioprocess Technology 5 8 (2012): 3014-3020. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867678555&partnerID=MN8TOARS.
    10.1007/s11947-011-0609-4
  30. Oliveira, C.; Guimarães, P.M.R.; Domingues, L.. "Recombinant microbial systems for improved ß-galactosidase production and biotechnological applications". Biotechnology Advances 29 6 (2011): 600-609. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053439614&partnerID=MN8TOARS.
    10.1016/j.biotechadv.2011.03.008
  31. Oliveira, C.; Nicolau, A.; Teixeira, J.A.; Domingues, L.. "Cytotoxic effects of native and recombinant frutalin, a plant galactose-binding lectin, on Hela cervical cancer cells". Journal of Biomedicine and Biotechnology 2011 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84855172657&partnerID=MN8TOARS.
    10.1155/2011/568932
  32. Domingues, L.; Guimarães, P.M.R.; Oliveira, C.. "Metabolic engineering of Saccharomyces cerevisiae for lactose/whey fermentation". Bioengineered Bugs 1 3 (2010): 164-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955173396&partnerID=MN8TOARS.
    10.4161/bbug.1.3.10619
  33. Oliveira, C.; Teixeira, J.A.; Schmitt, F.; Domingues, L.. "A comparative study of recombinant and native frutalin binding to human prostate tissues". BMC Biotechnology 9 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-70350714680&partnerID=MN8TOARS.
    10.1186/1472-6750-9-78
  34. Oliveira, C.; Costa, S.; Teixeira, J.A.; Domingues, L.. "CDNA Cloning and Functional Expression of the a-d-Galactose-Binding Lectin Frutalin in Escherichia coli". Molecular Biotechnology 43 3 (2009): 212-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350567797&partnerID=MN8TOARS.
    10.1007/s12033-009-9191-7
  35. Oliveira, C.; Felix, W.; Moreira, R.A.; Teixeira, J.A.; Domingues, L.. "Expression of frutalin, an a-d-galactose-binding jacalin-related lectin, in the yeast Pichia pastoris". Protein Expression and Purification 60 2 (2008): 188-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-45449112140&partnerID=MN8TOARS.
    10.1016/j.pep.2008.04.008
  36. Oliveira, C.; Teixeira, J.A.; Lima, N.; Da Silva, N.A.; Domingues, L.. "Development of stable flocculent Saccharomyces cerevisiae strain for continuous Aspergillus niger ß-galactosidase production". Journal of Bioscience and Bioengineering 103 4 (2007): 318-324. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248213118&partnerID=MN8TOARS.
    10.1263/jbb.103.318
  37. Domingues, L.; Oliveira, C.; Castro, I.; Lima, N.; Teixeira, J.A.. "Production of ß-galactosidase from recombinant Saccharomyces cerevisiae grown on lactose". Journal of Chemical Technology and Biotechnology 79 8 (2004): 809-815. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344599233&partnerID=MN8TOARS.
    10.1002/jctb.1025
Thesis / Dissertation
  1. Oliveira, Carla. "Expression and production of recombinant frutalin in different expression systems and evaluation of its biomedical applications". PhD, Universidade do Minho, 2009. https://repositorium.sdum.uminho.pt/handle/1822/10219.
  2. Oliveira C.. "Production of beta-galactosidase by recombinant yeast - Development of a stable production system". Master, Universidade do Minho, 2005. http://repositorium.sdum.uminho.pt/handle/1822/918.

Intellectual property

Patent
  1. Oliveira C.; Lopes C; Carsanba E; Carvalho AP; Oliveira AS. 2023. "Compositions and methods for using previously cultured cells".
    Pending
  2. Oliveira C.; Lopes L; Carsanba E; Carvalho AP; Oliveira AS. 2022. "Compositions and methods for using previously cultured cells". United States.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10 Fermentation Concepts Online advanced course “Deep Tech for Innovators”
Católica University of Porto (Online)
2023/07/03 Optimizing the removal of phenolic compounds from sugarcane syrup with activated charcoal ICP2023 - XXXI International Conference on Polyphenols
(Nantes, France)
2022/04/07 Characterization of beta-farnesene yeast producer during fed-batch fermentation 3rd BioIberoAmerica - IBERO-AMERICAN CONGRESS ON BIOTECHNOLOGY
INL – International Iberian Nanotechnology Laboratory (Braga)
2022/04/07 Modulation of polyphenols in beta-farnesene fed-batch fermentation 3rd BioIberoAmerica - IBERO-AMERICAN CONGRESS ON BIOTECHNOLOGY
INL – International Iberian Nanotechnology Laboratory (Braga)
2022/02/25 Demystifying the Strain Design and Fermentation Lab CBQF BioTalks
Católica University of Porto (Porto, Portugal)
2019/05/17 Recombinant production and purification of the R248W mutant of human p53 in Escherichia coli 4th Meeting of Medicinal Biotechnology
(Porto, Portugal)
2017/12/07 Enhancing the enzymatic saccharification of whole slurry from autohydrolyzed Eucalyptus globulus wood by supplementation with a recombinant carbohydrate-binding module MICROBIOTEC’17 - Portuguese Congress of Microbiology and Biotechnology
(Porto, Portugal)
2017/07/06 Genetic engineering approaches for enhanced lignocellulosic-based bioprocesses Annual meeting of the Centre of Biological Engineering
Universidade do Minho (Braga, Portugal)
2017/02/03 Recombinant Protein Production CEB - CIIMAR joint meeting
CIIMAR (Matosinhos, Portugal)
2013/11/04 The novel Fh8 fusion tag: a comparison with other fusion systems for efficient soluble overexpression and purification of recombinant proteins in Escherichia coli PEGS Europe - Protein and Antibody Engineering Summit 2013
(Lisboa, Portugal)
2013/05/22 Production of recombinant beta-galactosidase in different microorganisms and biotechnological applications 2º Encontro de Biotecnologia Microbiana e Farmacêutica
Faculdade de Farmácia, Universidade do Porto (Porto, Portugal)
2012/12/05 Production and application of biomolecules - from polysaccharides to lectins XIa REUNIÃO REGIONAL NORDESTE DA SBBq and IVth International Symposium in Biochemistry of Macromolecules and Biotechnology
(Recife, Brazil)
2011/02/16 Evaluation of a novel Escherichia coli fusion system for overproduction of recombinant immunogenic proteins RPP6 - 6th Conference on Recombinant Protein Production
(Vienna, Austria)
2010/10/23 Expression and production of recombinant frutalin in different expression systems and evaluation of its biomedical applications 2nd Meeting of the IBB – Institute for Biotechnology and Bioengineering
University of Minho (Braga, Portugal)
2008/10/28 Construction of microbial strains for the production of proteins with therapeutic interest - lectins Semana da Escola de Engenharia da Universidade do Minho 2008: “Parcerias de Ensino e Investigação”
University of Minho (Guimarães, Portugal)
2005 Molecular yeast solutions for whey bioremediation Proceedings of the 24th Annual General Meeting of the European Culture Collections Organization
(Riga, Latvia)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020 - 2024/03 Strategies to overcome industrial stress factors in engineered Saccharomyces cerevisiae and impact on bioreactor fermentation
Supervisor
 Biotechnology (PhD)
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2020 - 2024/01 Effect of polyphenols on Saccharomyces cerevisiae fed-batch fermentation
Supervisor
 Biotechnology (PhD)
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2021 - 2023 Sustainable production of postbiotics for food applications
Co-supervisor
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2021 - 2021/07 Develop and optimize a fermentation seed build process for backcrossed farnesene yeast strains
Supervisor
 Biomedical Engineering (Master)
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2018 - 2019 Developing new anticancer drug candidates by targeting p53
Supervisor
 Engenharia Biomédica (Master)
Universidade do Minho, Portugal
2018 - 2019 Glycanzyme - Characterisation of novel enzymes for protein glycoengineering
Co-supervisor
 Biotecnologia (Master)
Universidade do Minho, Portugal
2017 - 2018 Innovative Ochratoxin A (OTA) extraction platforms using OTA-binding proteins
Supervisor
 Biotecnologia (Master)
Universidade do Minho, Portugal
2015 - 2016 In vitro evaluation and characterization of mineral and organic mycotoxin binders
Co-supervisor
 MSc in Bioengineering (Master)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2014 - 2015 Clivagem e caracterização de frutalina recombinante produzida em Escherichia coli
Supervisor
 Engenharia Biomédica (Master)
Universidade do Minho, Portugal
2014 - 2015 Expressão e aplicação de uma lectina recombinante de interesse biomédico
Co-supervisor
 Engenharia Biomédica (Master)
Universidade do Minho, Portugal
2013 - 2014 Production of recombinant carbohydrate-binding modules in Pichia pastoris and their application in the modification of paper fibers
Supervisor
 Master in Bioengineering (Master)
Universidade do Minho, Portugal
2012 - 2013 Engineering yeast tolerance to inhibitory lignocellulosic biomass
Co-supervisor
 Master in Bioengineering (Master)
Universidade do Minho, Portugal
2011 - 2012 Genetic engineering of the riboflavin producer Ashbya gossypii
Co-supervisor
 Master in Bioengineering (Master)
Universidade do Minho, Portugal
2011 - 2012 Genetic engineering of Ashbya gossypii: application of the Cre-LoxP system for rescue and reuse of selection markers
Co-supervisor
 Master in Bioengineering (Master)
Universidade do Minho, Portugal
2009 - 2010 Inhibition of the proliferation of human cancer cell lines by a recombinant lectin (frutalin)
Co-supervisor
 Engenharia Biomédica (Master)
Universidade do Minho, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017 - 2018 P2G2P - Proteome 2 Gene 2 Protein Hands-on-Course - 2nd Edition (2018/03/26 - 2018/03/28)
Workshop (Co-organisor)
 Universidade do Minho Centro de Engenharia Biológica, Portugal
2015 - 2016 P2G2P - Proteome 2 Gene 2 Protein Hands-on-Course - 1st Edition (2016/12/20 - 2016/12/22)
Workshop (Co-organisor)
 Universidade do Minho Centro de Engenharia Biológica, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023 - 2023 Breakthrough Leadership Program
Workshop
INSEAD, France
2022 - 2022 Team Management
Workshop
CITEVE, Portugal
2015/06/15 - 2015/06/18 Proteomics course: gel based protein separation by two dimensional gel electrophoresis and protein characterization by MALDI-TOF/TOF mass spectrometry
Workshop
 Proteomics course: gel based protein separation by two dimensional gel electrophoresis and protein characterization by MALDI-TOF/TOF mass spectrometry
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2008/06/16 - 2008/06/20 Confocal Microscopy in Cell Biology
Workshop
 Confocal Microscopy in Cell Biology
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2007/05/16 - 2007/05/18 Animal Cell Culture
Workshop
 Animal Cell Culture
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023 Pichia pastoris como ferramenta para produção de vacinas: limitações, desafios e oportunidades
(Thesis) Main arguer
 Sérgio Miguel Carneiro Sousa (Master)
Universidade do Minho, Portugal
2015 Novel strategies to combat Gram-negative bacterial pathogens using bacteriophage proteins
(Thesis) Main arguer
 Joana Teixeira da Costa Lucas (Master)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2013 Elucidation of the molecular mechanisms underlying the cytotoxic effect of recombinant frutalin in human tumor cells
(Thesis) Main arguer
 Sofia Emanuela Soares Mendonça (Master)
Universidade do Minho, Portugal
2012 Physiological characterization of Ashbya gossypii and strain development for recombinant protein production
(Thesis) Arguer
 Orquídea Marília de Castro Ribeiro (PhD)
Universidade do Minho, Portugal
2011 Desenvolvimento da produção de proteínas recombinantes e respetivos anticorpos com interesse de diagnóstico e/ou terapêutico através de um novo sistema de fusão em Escherichia coli
(Thesis) Main arguer
 Armando Hugo Soares Marques (Master)
Universidade do Minho, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - 2019 Laboratories of Chemical Technology 3rd year of the Integrated MSc in Biological Engineering (Mestrado integrado) Universidade do Minho, Portugal
2004 - 2019 Practical Contents of Molecular Biotechnology Master in Chemical and Biological Engineering, Integrated Master in Biomedical Engineering, Master in Bioengineering and Master in Biotechnology (Licenciatura) Universidade do Minho, Portugal
2013 - 2014 Laboratories of Chemical Technology Integrated MSc in Biological Engineering (Mestrado integrado) Universidade do Minho, Portugal
2010 - 2011 Biochemical Engineering Integrated MSc in Biological Engineering (Mestrado integrado) Universidade do Minho, Portugal
2010 - 2011 Separation Processes and Enzyme Technology MSc in Biotechnology and Bioentrepeneurship in Aromatic and Medicinal Plants (Mestrado) Universidade do Minho, Portugal
2010 - 2011 Food Biotechnology 4th year of the MSc in Biological Engineering (Mestrado integrado) Universidade do Minho, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2011 - Current Occasional reviewer for different international journals: Biotechnology for Biofuels and Bioproducts; BioMed Research International; Journal of Chemical Technology and Biotechnology; Brazilian Journal of Chemical Engineering; BioMed Research International; Brazilian Journal of Microbiology; Applied Microbiology and Biotechnology; PLOS ONE; BMC Biotechnology; Process Biochemistry; Microbial Biotechnology; Brazilian Journal of Chemical Engineering; FEBS journal, etc
Evaluator
2019 - 2019 Estonia Research Council
Evaluator

Other jury / evaluation

Activity description Institution / Organization
2022 - 2022 Evaluator of the PhD Work-Plan: SUSPLA: development of PLA biofilms from food waste, incorporated with bioactive preserving molecules" Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2013 - 2016 Evaluater of discipline "Research Project" of MSc in Bioengineering Universidade do Minho, Portugal
Distinctions

Other distinction

2008 Young Scientist Meeting Grant
Federation Of European Microbiological Societies, United Kingdom
2007 Young Scientist Meeting Grant
Federation Of European Microbiological Societies, United Kingdom