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André Luz completed the Bachelor’s Degree in Medicinal Chemistry in 2015 and the Master’s Degree in Medicinal Chemistry in 2017, both by the Faculty of Sciences and Technology of the University of Coimbra. During his Master’s Degree he did research on Luis Arnaut’s lab, where he developed skills in the areas of organic chemistry, photochemistry, cell-based assays and animal science, both theoretical and practical. The research culminated with the development of a scientific article and his master’s thesis, which was awarded with the Best Portuguese Master Thesis in Medicinal Chemistry prize. Currently André is enrolled in an FCT-funded PhD on Rui Moreira’s lab, in the Medicinal Chemistry group of the Research Institute for Medicines of the University of Lisbon, working in the synthesis and development of new antinecroptotic small molecules with potential application on CNS disorders. During his academic path he simultaneously participated in academic associations, was student representative during the bachelor’s degree, enrolled on entrepreneurship contests and co-founded and worked on a Junior Enterprise in the chemistry field.
Identification

Personal identification

Full name
André Luz

Citation names

  • André F. S. Luz

Author identifiers

Ciência ID
8F16-5688-9F2C
ORCID iD
0000-0003-3611-4598

Email addresses

  • andrefluz@ff.ulisboa.pt (Professional)

Addresses

  • Avenida Prof. Gama Pinto, 1649-003, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences - Physical Chemistry
  • Natural sciences - Biological Sciences
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2017/11/15 - 2021/11/15
Ongoing
PhD in Chemistry (Doutoramento)
Major in Specialization in Medicinal Chemistry
Universidade de Coimbra Centro de Química de Coimbra, Portugal
"Computational analysis, de novo design, validation and target identification of necroptosis inhibitors" (THESIS/DISSERTATION)
2015/09/01 - 2017/09/30
Concluded
Master’s degree in Medicinal Chemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"5,10,15,20-Tetrakis(2,6-difluoro-3-sulfonylphenyl)bacteriochlorin: from synthesis to the preclinical studies" (THESIS/DISSERTATION)
18/20
2016 - 2016
Concluded
Laboratory Animal Science Category C Course (FELASA accreditation) (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/08/01 - 2015/08/31
Concluded
Summer internship (Outros)
Major in Neuroendocrinology and Aging Group
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012/09/01 - 2015/07/31
Concluded
Bachelor's degree in Medicinal Chemistry (Licenciatura)
Universidade de Coimbra Departamento de Química, Portugal
"LUZ10 suitable for therapy and diagnose: photochemical and photophysical characterization" (THESIS/DISSERTATION)
17/20
2014/09 - 2015/01
Concluded
English Course (B2 Level) (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
2014/08/01 - 2014/08/30
Concluded
Summer Internship (Outros)
Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
2014/02 - 2014/06
Concluded
English Course (B1 Level) (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
Affiliation

Others

Category
Host institution
Employer
2017/11/15 - Current Bolseiro de Doutoramento Universidade de Lisboa Faculdade de Farmácia, Portugal
Outputs

Publications

Conference poster
  1. André F. S. Luz; Andreia Sofia da Costa Vieira (8211-890B-78C6); Rita C. Guedes; Lígia Catarina Gomes da Silva (3B1B-F867-0C15); Moreira, Rui. "Synthetic approaches to 3-substituted 1H-pyrazole-5-carbaldehydes as precursors for antinecroptotic inhibitors". Paper presented in XXVI Nacional Meeting of the Portuguese Society of Chemistry, 2019.
  2. André F. S. Luz; Rita C. Guedes; Moreira, Rui; Lígia Catarina Gomes da Silva (3B1B-F867-0C15). "Synthesis of 3-substituted 1H-pyrazole-5-carbaldehydes as precursors of necroptotic cell death inhibitors". Paper presented in 4th Colégio de Química of University of Lisbon Congress, 2019.
  3. André F. S. Luz; Schaberle, FA; Helder T. Soares; Lobo, Ana Catarina S. ; Arnaut, Luis G.. "LUZ10, a New Water-soluble Bacteriochlorin Photosensitizer: photochemical, in vitro and in vivo characterization". Paper presented in XXV Nacional Meeting of the Portuguese Society of Chemistry, 2017.
  4. André F. S. Luz; Schaberle, FA; Helder T. Soares; Pinto, Sara M. A.; Pereira, Mariette M.; Arnaut, Luis G.. "Synthesis and Characterisation of LUZ10, a Soluble Bacteriochlorin for Cancer Treatment". Paper presented in V National Chemistry Student's Meeting, 2017.
  5. André F. S. Luz; Schaberle, FA; Helder T. Soares; Arnaut, Luis G.. "Characterisation of LUZ10, a Soluble Bacteriochlorin for PDT Treatment". Paper presented in XXII Portuguese-Galician Chemistry Meeting, 2016.
  6. André F. S. Luz; Schaberle, FA; Helder T. Soares; Arnaut, Luis G.. "Photochemical and photophysical characterisation of a soluble bacteriochlorin for biomedical applications". Paper presented in IV National Chemistry Students Meeting, 2016.
Journal article
  1. Luz, André F.S.; Pucelik, Barbara; Pereira, Mariette M.; Dabrowski, Janusz M.; Arnaut, Luis G.. "Translating phototherapeutic indices from in vitro to in vivo photodynamic therapy with bacteriochlorins". Lasers in Surgery and Medicine 50 5 (2018): 451-459. http://dx.doi.org/10.1002/lsm.22931.
    Published • 10.1002/lsm.22931
Thesis / Dissertation
  1. Andre F. S. Luz. "5,10,15,20-Tetrakis(2,6-difluoro-3-sulfonylphenyl)bacteriochlorin: from synthesis to the preclinical studies". Master, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2017. http://hdl.handle.net/10316/83243.
  2. Andre F. S. Luz. "LUZ10 suitable for therapy and diagnose: photochemical and photophysical characterization". Degree, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2015.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2017/06/08 Synthesis and Characterisation of a water soluble bacteriochlorin photosensitizer XVI International Photodynamic Association World Congress
International Photodynamic Association (Coimbra, Portugal)
2016 Characterisation of a Soluble Bacteriochlorin for Cancer Treatment II NEQ/AAC’s Scientific Meeting
NEQ/AAC (Coimbra, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2017/01 - 2017/06/13 XVI International Photodynamic Association World Congress (2017/06/08 - 2017/06/13)
Congress (Co-organisor)
International Photodynamic Association, Portugal

Universidade de Coimbra, Portugal
2016/06 - 2017/04/10 V National Chemistry Students Meeting (2017/04/07 - 2017/04/10)
Congress (Co-organisor)
Universidade de Coimbra Departamento de Química, Portugal
2016/01 - 2016/03 III Job and Entrepreneurship Fair of the Department of Chemistry of University of Coimbra (2016/02/25 - 2016/02/26)
Congress (Co-organisor)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/01/01 - 2015/02/25 II Job and Entrepreneurship Fair of the Department of Chemistry of University of Coimbra (2015/02/25 - 2015/02/25)
Congress
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/01/01 - 2014/05/01 4th Portuguese Young Chemist Meeting (2014/04/29 - 2014/05/01)
Congress (Co-organisor)
Universidade de Coimbra, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2019/07/24 - 2019/07/26 XXVI Nacional Meeting of the Portuguese Society of Chemistry
Congress
XXVI Nacional Meeting of the Portuguese Society of Chemistry
Sociedade Portuguesa de Química, Portugal
2018/04/10 - 2018/04/10 Académica Start UC - "A Química do Empreendedorismo"
Conference
A Química do Empreendedorismo - Académica Start UC
Universidade de Coimbra, Portugal
2017/07/16 - 2017/07/19 XXV Nacional Meeting of the Portuguese Society of Chemistry
Congress
XXV Nacional Meeting of the Portuguese Society of Chemistry
Sociedade Portuguesa de Química, Portugal
2016/11/09 - 2016/11/11 XXII Portuguese-Galician Chemistry Meeting
Congress
XXII Portuguese-Galician Chemistry Meeting
Sociedade Portuguesa de Química, Portugal
2016/03/18 - 2016/03/20 IV National Chemistry Students Meeting
Congress
IV National Chemistry Students Meeting
Universidade do Porto, Portugal
2015/01 - 2015/12 Poliempreende – Entrepreneurship Contest
Workshop
Poliempreende – Entrepreneurship Contest
Instituto Politécnico de Coimbra, Portugal
2014/01 - 2015/12 Representative of the Chemistry and Medicinal Chemistry Bachelor’s students for the Commission of Queima das Fitas
Festival
Queima das Fitas
Universidade de Coimbra, Portugal
2013 - 2015 Representative of the bachelor’s degree in Medicinal Chemistry before the Pedagogical Council of the Faculty of Sciences and Technology of the University of Coimbra
Round table
Pedagogical Council of the Faculty of Sciences and Technology of the University of Coimbra
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Association member

Society Organization name Role
2017/01 - Current Molecular Junior Enterprise Co-founder and Chief Operating Officer
2019/01 - 2020/01 Molecular Junior Enterprise Lisbon Co-founder and Chief Executive Officer
2015/01 - 2017/12 National Chemistry Students Association 2015 - Committee’s Substitute; 2016 - Treasurer; 2017 – Chairman
2015/01 - 2015/12 Chemistry Students' Association of University of Coimbra Coordinator of the division for career opportunities
2013/01 - 2015/12 Chemistry Students' Association of University of Coimbra 2013/2014 - Collaborator; 2015 - Coordinator of the division for career opportunities

Conference scientific committee

Conference name Conference host
2015/11/19 - 2015/11/20 I NEQ/AAC’s Scientific Meeting Chemistry student’s association of University of Coimbra
Distinctions

Award

2018 Best Portuguese Master Thesis in Medicinal Chemistry
Sociedade Portuguesa de Química, Portugal
2017 Best pitch on Angelini University Award (Entrepreneurship Competition)
Angelini Farmacêutica Lda, Portugal
2015 Winner of Bioempreende (Entrepreneurship Competition)
Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra, Portugal
2015 Top 3% of Students
Universidade de Coimbra, Portugal
2014 Top 3% of Students
Universidade de Coimbra, Portugal