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Inês graduated in Biochemistry from the University of Beira Interior in 2021. During her time there, she had the opportunity to participate in the development of a project that aimed to study the immune response in the sensing of pathological peptides from Alzheimer's disease, at the Dr. Elsa Rocha lab. Moreover, there she seized the opportunity to do an internship at the Ludwig Institute for Cancer Research, University of Oxford, through the ERASMUS+ program. At Oxford, she worked as a lab assistant, contributing to projects investigating the modeling of a key cell protein, Aryl Hydrocarbon Receptor (AHR), in various pathological contexts. Following her undergraduate studies, she pursued her studies within the Clinical Biochemistry MSc program at the University of Aveiro. Inês developed her master's thesis at i3S in 2022/2023, in the Immune Sensing and Signaling Dynamics, part of the ImmunoHub ERA Chair Project, led by Dr. Pedro Moura Alves, where she studied the effects of various clinically approved drugs on the modulation of the AHR. She aimed to unravel mechanisms underlying different diseases, comprehend drug resistance, and assess drug repurposing opportunities. In 2024, after a year as a Research Fellow at i3S, Inês began her PhD in the Molecular and Cell Biology Program at the Instituto de Ciências Biomédicas Abel Salazar, University of Porto, where she continues her work with the same research group. Her current research interests focus on deciphering the complexities of AHR in drug sensing, with the goal of understanding its impact on treatment efficacy.
Identification

Personal identification

Full name
Inês Castro da Silva Almeida
Date of birth
2000/02/21
Gender
Female

Citation names

  • Castro-Almeida, Inês

Author identifiers

Ciência ID
8F13-D213-FF6B
ORCID iD
0009-0008-3748-501X

Email addresses

  • ialmeida@i3s.up.pt (Professional)

Telephones

Telephone
  • 226 074 90 Ext.: 6154 (Professional)

Addresses

  • i3S, Rua Alfredo Allen 208, 4200-135, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2024/10/22 - 2028/10/22
Ongoing
Biologia Molecular e Celular (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/12/23 - 2024/06/18
Concluded
Formação com Investigação em Ciências Biomoleculares (Pós-Graduação)
Major in Investigação Científica
Universidade Nova de Lisboa, Portugal
20
2021/10/11 - 2023/12/20
Concluded
Bioquímica (Mestrado)
Major in Bioquímica Clínica
Universidade de Aveiro, Portugal
"T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target." (THESIS/DISSERTATION)
19 / 20
2018/09/01 - 2021/06/30
Concluded
Bioquímica (Licenciatura)
Universidade da Beira Interior, Portugal
"Study of the modulation of dendritic cells and differentiation of CD8+ T lymphocytes in the sensing of pathological peptides from Alzheimer's disease." (THESIS/DISSERTATION)
16 / 20
2016/09/15 - 2018/06/22
Concluded
Formação em Científico-Humanístico de Ciências e Tecnologias (Ensino secundário)
Major in Ciências da Natureza
Escola Secundária Marques de Castilho, Portugal
2017/01 - 2017/04
Concluded
Curso Avançado em Regulação Celular (Outros)
Major in Biologia Celular e Molecular
Instituto de Educação e Cidadania (IEC), Portugal
2014/09 - 2014/12
Concluded
Curso Avançado em Fisiologia Celular (Outros)
Major in Biologia Celular e Molecular
Instituto de Educação e Cidadania (IEC), Portugal
Affiliation

Science

Category
Host institution
Employer
2024/01/01 - Current Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/09/19 - 2023/12/21 Research Trainee (Research) Universidade de Aveiro, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/07/02 - 2021/10/15 Research Trainee (Research) Ludwig Institute for Cancer Research Oxford Branch, United Kingdom
2021/02/22 - 2021/06/04 Research Trainee (Research) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Projects

Grant

Designation Funders
2024/11/01 - 2028/11/01 AHR on T(AHR)get: Dissecting the Impact of Aryl Hydrocarbon Receptor Modulation in Disease and Therapy
2024.01822.BD
PhD Student Fellow
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
2024/05/13 - 2024/05/24 T(AHR)get 2.0- Upgrading an MST-based assay to unveil ligand binding to the AHR.
MOSBRI-2023-222
Researcher
EMBL-Sample Preparation and Characterization (SPC), Netherlands
MOlecular-Scale Biophysics Research Infrastructure (MOSBRI)

Contract

Designation Funders
2024/01/01 - Current An Immunological Hub of Excellence in Porto tailored to fulfil the ERA Priorities
H2020-WIDESPREAD-2018-951921
Research Fellow
European Commission
Outputs

Publications

Conference poster
  1. Castro-Almeida, Inês; Aleksandra Janowska; Rory Saitch; Yilong Lian ; Alberto Delgado; Jonas Protze; Pedro Tiago Cardoso Curto; Pedro Moura-Alves. "AHR on T(AHR)get: Dissecting the Impact of Aryl Hydrocarbon Receptor Modulation in Disease and Therapy". Paper presented in At the Crossroads of Neuroscience & Immunology: Advances and Innovations | ERA CHAIRS ANNUAL MEETING IMMUNOHUB & NCBIO, 2024.
  2. Castro-Almeida, Inês; Aleksandra Janowska; Rory Saitch; Yilong Lian ; Alberto Delgado; Jonas Protze; Pedro Moura-Alves. "T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target". Paper presented in iMED Innovate Competition, Lisboa, Portugal, 2023.
  3. Castro-Almeida, Inês; Aleksandra Janowska; Rory Saitch; Yilong Lian ; Alberto Delgado; Jonas Protze; Pedro Moura-Alves. "T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target". Paper presented in II TOXRUN International Congress, Porto, Portugal, 2023.
  4. Castro-Almeida, Inês; Aleksandra Janowska; Rory Saitch; Yilong Lian ; Alberto Delgado; Jonas Protze; Pedro Moura-Alves. "T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target". Paper presented in XIV Biochemistry Day, Aveiro, Portugal, 2023.
  5. Castro-Almeida, Inês. "Examining the heart rate evolution in individuals recovering from COVID-19, during moderate physical exercise". Paper presented in XIII Biochemistry Day, Aveiro, Portugal, 2022.
Journal article
  1. Jonic, Natalija; Koprivica, Ivan; Chatzigiannis, Christos M.; Tsiailanis, Antonis D.; Kyrkou, Stavroula G.; Tzakos, Eleftherios Paraskevas; Pavic, Aleksandar; et al. "Development of FluoAHRL: A Novel Synthetic Fluorescent Compound That Activates AHR and Potentiates Anti-Inflammatory T Regulatory Cells". Molecules 29 13 (2024): 2988. http://dx.doi.org/10.3390/molecules29132988.
    10.3390/molecules29132988
Thesis / Dissertation
  1. "T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target". Master, Universidade de Aveiro, 2023.
  2. "Study of the modulation of dendritic cells and differentiation of CD8+ T lymphocytes in the sensing of pathological peptides from Alzheimer's disease". Degree, Universidade da Beira Interior, 2021.

Other

Other output
  1. BioSphere (Canal de Youtube). Projeto que visa entregar educação, na área da biologia, de uma forma dinâmica, à comunidade estudantil. 2024. Castro-Almeida, Inês. https://www.youtube.com/@Bio.Sphere..
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/02/20 AHR on T(AHR)get: Dissecting the Impact of Aryl Hydrocarbon Receptor Modulation in Disease and Therapy 11th McBiology Symposium
i3S- Instituto de Investigação e Inovação em Saúde, Universidade do Porto (Porto, Portugal)
2024/10/24 AHR on T(AHR)get: Dissecting the Impact of Aryl Hydrocarbon Receptor Modulation in Disease and Therapy XXII National Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal (Aveiro, Portugal)
2024/05/24 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target VII iBiMED Symposium
Universidade de Aveiro (Aveiro, Portugal)
2024/05/24 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target SINAL 2024: 11th meeting on signal transduction
Universidade de Coimbra (Coimbra, Portugal)
2024/05/09 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target 17th Encontro de Investigação Jovem da Universidade do Porto (IJUP)
Universidade do Porto (Porto, Portugal)
2024/04/10 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target XV Biochemistry Day - Contribution of Biochemistry for Sustainability
Universidade de Aveiro (Aveiro, Portugal)
2023/11/17 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target. 10th i3S Annual Meeting
i3S- Instituto de Investigação e Inovação em Saúde, Universidade do Porto (Porto, Portugal)
2023/09/27 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target sPITCHless Med+
Engineering in Medicine and Biology Society (EMBS) from University of Aveiro (Aveiro, Portugal)
2023/09/13 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target. Immune Crosstalk
ImmunoHUB Era Chair, I3S (Porto, Portugal)
2023/05/10 T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to a therapeutic target. 16th Encontro de Investigação Jovem da Universidade do Porto (IJUP)
Universidade do Porto (Porto, Portugal)
2022/05/18 Career Advisor Seminar Alumni Talks
Associação de Alunos da Universidade da Beira Interior (AAUBI) (Covilhã, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/02/01 - 2023/03/17 I ImmunoHub Annual Meeting in Infection & Immunity (2023/03/17)
Meeting (Member of the Organising Committee)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/01/01 - 2023/03/08 Criminal Insights: A Forensic Scientific Event (2023/03/08)
Seminar (Member of the Organising Committee)
Scientific Junior Value, Portugal
2022/10/01 - 2022/12/17 Learn to Help: A fundraising initiative for charity organizations (2022/12/17)
Meeting (Member of the Organising Committee)
Scientific Junior Value, Portugal
2022/09/01 - 2022/11/05 Work Safe: Event about financial literacy (2022/11/05)
Seminar (Member of the Organising Committee)
Scientific Junior Value, Portugal
2022/04/01 - 2022/06/18 3rd Save a Life: Workshop in First Aids (2022/06/18)
Workshop (Member of the Organising Committee)
Scientific Junior Value, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2025/02/20 - 2025/02/21 PhD Students Symposium
Symposium
11th McBiology Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/12/05 - 2024/12/06 Meeting on Neuroimmunology
Meeting
At the Crossroads of Neuroscience and Immunology: Advances and Innovations ImmunoHUB & NCBio ERA Chairs Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/11/14 - 2024/11/15 Research Institute Annual Meeting
Meeting
11th i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/11/12 - 2024/11/12 Webinar on Data Management for Clinical Research
Seminar
Data Management for Clinical Research
Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2024/10/24 - 2024/10/26 National Congress of Biochemistry
Congress
XXII National Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
2024/10/09 - 2024/10/09 Conferência de 30 anos da Fundação Bial (Sobre a Fisiologia da Mente)
Conference
Conferência 30 anos Fundação Bial 2024
Fundação Bial, Portugal
2024/10/03 - 2024/10/04 PhD Students Symposium
Symposium
7th PhDay: From Theory to Application: Research in Action
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/09/27 - 2024/09/27 Scientific Research Dissemination Exhibition
Exhibition
European Researchers Night 2024
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/05/24 - 2024/05/25 Meeting on Signal Transduction
Meeting
SINAL 2024: 11th meeting on signal transduction
Universidade de Coimbra, Portugal
2024/05/23 - 2024/05/24 Symposium on Biomedical Sciences
Symposium
VII iBiMED Symposium
Universidade de Aveiro Instituto de Biomedicina, Portugal
2024/05/21 - 2024/05/21 Workshop in Research Design with the Idea Puzzle Software
Workshop
Research Design with the Idea Puzzle Software
Universidade do Porto, Portugal
2024/05/15 - 2024/05/15 Webinar in Publishing in high-impact journals
Seminar
Publishing in high-impact journals - the author's trajectory
Elsevier Inc, United States
2024/05/13 - 2024/05/13 Workshop in Communicating Science in Politics
Workshop
Communicating Science in Politics
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/05/08 - 2024/05/10 Young Research Meeting from the University of Porto
Meeting
17th Encontro de Investigação Jovem da Universidade do Porto (IJUP)
Universidade do Porto, Portugal
2024/05/02 - 2024/05/02 Voluntary work at National Science Competitions
Other
National Science Competitions 2024
Universidade de Aveiro, Portugal
2024/04/18 - 2024/04/19 PhD Students Symposium
Symposium
10th McBiology Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/04/09 - 2024/04/09 Science Outreach for High School Students
Workshop
Ciência et al. - Programa Educativo i3S
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/03/19 - 2024/03/19 Webinar on Protein Structure and Function
Seminar
Structure Meets Function Webinar
Instruct-ERIC - Structural Biology European Research, United Kingdom
2024/03/12 - 2024/03/12 Voluntary work at National Championship of Mathematical Games
Other
17th National Championship of Mathematical Games
Universidade de Aveiro, Portugal
2024/03/06 - 2024/03/08 Online International Conference on Cancers
Conference
The 4th International Electronic Conference on Cancers
MDPI AG, Switzerland
2024/02/02 - 2024/02/02 Research Institute Open Day
Exhibition
3rd MSc Open Day
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/01/26 - 2024/01/26 Workshop in Clinical Biochemistry
Workshop
IX Clinical Biochemistry Workshop
Sociedade Portuguesa de Bioquímica, Portugal

Universidade do Algarve, Portugal
2022/12/06 - 2023/12/06 Seminars Cycle in Immunology
Seminar
Immune Crosstalk
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/11/30 - 2023/11/30 RNA Sequencing Webinar
Seminar
Unlocking the Transcriptome: A Journey into RNA Sequencing.
Novogene, Germany
2023/11/16 - 2023/11/17 Research Institute Annual Meeting
Meeting
10th i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/10/14 - 2023/10/14 Academic Projects Contest
Call
iMED Innovate Competition
iMED Conference, Portugal
2023/09/26 - 2023/09/28 Academic Projects Contest
Call
sPITCHless Med+
Engineering in Medicine and Biology Society (EMBS) chapter of Aveiro University, Portugal
2023/05/12 - 2023/05/12 Science Outreach for High School Students
Workshop
Ciência et al. - Programa Educativo i3S
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/05/10 - 2023/05/12 Young Research Meeting from the University of Porto
Meeting
16th IJUP
Universidade do Porto, Portugal
2023/04/27 - 2023/04/28 International Congress in Toxicology
Congress
II TOXRUN International Congress
Instituto Universitário de Ciências da Saúde Unidade de Investigação em Toxicologia, Portugal
2023/04/12 - 2023/04/19 Biochemistry Day Celebration Event
Conference
XIV Biochemistry Day
Universidade de Aveiro, Portugal
2023/03/19 - 2023/03/24 Training Program in Scientific Soft Skills
Workshop
Soft Transferable Skills Training Program
SupraLife, Portugal
2023/03/17 - 2023/03/17 Immunology Internal Forum
Conference
ImmunoHUB Annual Meeting 2023 - Infection and Immunity
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/02/23 - 2023/02/24 PhD Students Symposium
Symposium
9th McBiology Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/02/03 - 2023/02/03 Research Institute Open Day
Exhibition
2nd MSc Open Day
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/11/11 - 2022/11/11 Research Institute Annual Meeting
Meeting
9th Annual i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/03/27 - 2022/05/04 Biochemistry Day Celebration Event
Conference
XIII Biochemistry Day
Universidade de Aveiro, Portugal
2022/04/20 - 2022/04/20 Animal Model Seminar
Seminar
From In silico to Animal Models For the Study of Human Diseases
Universidade de Aveiro, Portugal
2021/03/26 - 2021/03/28 Portuguese Chemistry Students Colloquium
Meeting
Digital Colloquium of Chemistry Students in Portugal 2021
Associação Nacional de Estudantes de Química (ANEQ), Portugal
2020/05/15 - 2021/01/21 Career Advisor Seminar
Seminar
Made in UBI
Universidade da Beira Interior, Portugal
2020/10/10 - 2020/10/11 Researchers Meeting
Meeting
IV meet.Lab
Núcleo de Estudantes de Química da Associação Académica de Coimbra (NEB/AAC), Portugal
2020/10/10 - 2020/10/10 Workshop on the Biology of Reproduction
Workshop
Strategies and Mechanisms of Action of Spermicides
Núcleo de Estudantes de Química da Associação Académica de Coimbra (NEB/AAC), Portugal
2020/06/15 - 2020/06/15 Invited Speaker to testify about my experience as a Bachelor student in Biochemistry, at Universidade da Beira Interior.
Exhibition
Online UBI days
Associação Académica da Universidade da Beira Interior (AAUBI), Portugal
2020/06/09 - 2020/06/09 Workshop on Vaccine Production
Workshop
Produção de Vacinas
Eppendorf Brazil, Brazil
2020/05/17 - 2020/05/18 UBI Alumni Talks
Meeting
UBI Alumni Talks
Associação Académica da Universidade da Beira Interior (AAUBI), Portugal
2020/05/13 - 2020/05/16 Training Program in Academic Soft Skills
Workshop
Scale Up
Scientific Junior Value, Portugal
2020/04/07 - 2020/04/27 Online Biochemistry and Chemistry Days
Conference
Science at Home
UBIQuímica, Portugal
2020/02/19 - 2020/02/19 Career Advisor Seminar
Seminar
Acabei a Licenciatura... e agora?
Núcleo de Estudantes Socialistas da Universidade da Beira Interior (NESDUBI), Portugal
2019/04/03 - 2019/04/04 Biochemistry and Chemistry Days
Conference
Jornadas de Química e Bioquímica
UBIQuímica, Portugal

Association member

Society Organization name Role
2024/08/30 - Current Portuguese Biochemical Society Member
2022 - 2023 Scientific Junior Value (Junior Enterprise) Membro do Setor de Relações Científicas
2021 - 2022 Chemistry Students Association from the University of Aveiro (NEQ-AAUAv) Membro do Setor de Comunicação e Imagem
2021 - 2021 Chemistry Students Association from the University of Beira Interior (UBIQuímica) Colaborador
2020 - 2021 Tuna Académica Feminina da Universidade da Beira Interior (Encantatuna)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/04/09 - 2024/04/09 Ciência et al. - Programa Educativo i3S (Ensino secundário) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/05/12 - 2023/05/12 Ciência et al. - Programa Educativo i3S (Ensino secundário) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Mentoring / Tutoring

Topic Student name
2024/09/05 - 2024/09/09 Ciência Viva - "Conversas entre hospedeiro e micróbio através do AHR” (summer internship for middle school students) Filipa Dias
2024/09/05 - 2024/09/09 Ciência Viva - "Conversas entre hospedeiro e micróbio através do AHR” (summer internship for middle school students) Benedita Cruz
2023/07/03 - 2023/07/07 Ciência Viva – “Am I under attack? What AHR bacteria talking about?” (summer internship for high school students) Mariana Novais
2023/07/03 - 2023/07/07 Ciência Viva – “Am I under attack? What AHR bacteria talking about?” (summer internship for high school students) Wendy Travessa

Other jury / evaluation

Activity description Institution / Organization
2023/03/17 - 2023/03/17 Member of the jury for evaluation of oral communications (I ImmunoHUB Annual Meeting - Infection & Immunity) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Distinctions

Award

2024 Pitch with an Honored Mention (XV Biochemistry Day)
Universidade de Aveiro, Portugal
2024 Best Oral Presentation award (17th IJUP)
Universidade do Porto, Portugal
2024 Best Oral Communication award (XXII National Congress of Biochemistry)
Sociedade Portuguesa de Bioquímica, Portugal
2023 Poster with an Honored Mention (XIV Biochemistry Day)
Universidade de Aveiro, Portugal
2023 Best Oral Presentation award (16th IJUP)
Universidade do Porto, Portugal
2023 Best Oral Presentation award (sPITCHless Med+)
Engineering in Medicine and Biology Society (EMBS) chapter of Aveiro University, Portugal
2021 Erasmus + Fellowship
Universidade da Beira Interior, Portugal

Other distinction

2024 SPB Grant for XXII National Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
2023 Contest Finalist (iMED Innovate Competition)
iMED Conference, Portugal
2021 Biochemistry Class Best Student
Universidade da Beira Interior, Portugal