| Conference poster |
- Kussaba Miguel, Larissa; Simão, Márcio; Conceição, Natércia; M Leonor Cancela. "Histological characterization of zebrafish
mgp mutant (MGP_¿18)". Paper presented in IX SPB Clinical Biochemistry Workshop, 2024.
- D Varela; T Varela; Conceição, Natércia; ML Cancela. "miR-142a-3p regulates ZNF687 during MC3T3-E1 osteoblast differentiation".
Paper presented in IX Workshop de Bioquímica Clínica, 2024.
- M Chaves; B Ferreira; J Galhardas; S Guerreiro; E Houghton-Larsen; T Nehring; E Ninou; et al. "Bioinformatic analysis identifies
Oryzias latipes as a valid new model for analysis of MGP gene function". Paper presented in IX Workshop de Bioquímica Clínica,
2024.
- L Geraldo; L Miguel; Conceição, Natércia; J Santos; JK Venkatesan; M Cucchiarini; ML Cancela. "rAAV-mediated overexpression
of Gla-deficient mutant Matrix Gla Protein limits its potential to inhibit mineralization in SaOS2 cells". Paper presented
in IX Workshop de Bioquímica Clínica, 2024.
- T Varela; J Santos; A Hernández-Rodríguez; V Pinto; D Varela; Conceição, Natércia; ML Cancela. "Zebrafish-based drug screening
identifies candidate molecules for CDKL5 Deficiency Disorder therapeutic applications". Paper presented in CDKL5 Forum,
2023.
- D Varela; T Varela; Conceição, Natércia; ML Cancela. "Post-transcriptional regulation of znf687 during mc3t3-e1 osteoblast
differentiation". Paper presented in IV International Meeting of the Portuguese Society of Genetics, 2023.
- T Varela; D Varela; Conceição, Natércia; ML Cancela. "Zebrafish mutant as a model for cdkl5 deficiency disorder: insights
into neuron-skeletal defects". Paper presented in IV International Meeting of the Portuguese Society of Genetics, 2023.
- T Varela; J Santos; A Rodriguez; V Pinto; D Varela; Conceição, Natércia; ML Cancela. "Screening of drugs in zebrafish model
to rescue cdkl5 deficiency disorder phenotype". Paper presented in IV International Meeting of the Portuguese Society of
Genetics, 2023.
- M Simão; L Miguel; Conceição, Natércia; J Santos; ML Cancela. "Bioinformatic characterization of two MGP mutant proteins expressed
in zebrafish (Danio rerio)". Paper presented in IV International Meeting of the Portuguese Society of Genetics, 2023.
- T Varela; D Varela; Conceição, Natércia; ML Cancela. "Zebrafish mutant for CDKL5 display neuronal defects resembling CDKL5
deficiency disorder". Paper presented in FENS Regional Meeting 2023, 2023.
- D Varela; T Varela; Conceição, Natércia; ML Cancela. "Effect of bone-related transcription factors and methylation on ZNF687
transcriptional regulation". Paper presented in 50th ECTS, 2023.
- T Varela; D Varela; Conceição, Natércia; ML Cancela. "Zebrafish Mutant for Cdkl5 Mimics Phenotypes Associated with Human CDKL5
Deficiency Disorder". Paper presented in 26th Annual Meeting Sociedade Portuguesa de Genética Humana, 2022.
- D Varela; T Varela; Conceição, Natércia; ML Cancela. "Regulation of Znf687 during Osteoblast Differentiation". Paper presented
in 26th Annual Meeting Sociedade Portuguesa de Genética Humana, 2022.
- Poudel, Sunil; Martins, Gil; M Leonor Cancela; Gavaia, P. "The Sirt 1 activator resveratrol counteracts the doxorubicin-induced
effects on osteoclastogenesis". Paper presented in VI Interdisciplinary Approaches in Fish Skeletal Biology, 2022.
- Poudel, Sunil; Martins, Gil; M Leonor Cancela; Gavaia, P. "Regular supplementation with antioxidants rescues doxorubicin-induced
bone deformities and mineralization delay in zebrafish". Paper presented in VI Interdisciplinary Approaches in Fish Skeletal
Biology, 2022.
- T Varela; D Varela; Conceição, Natércia; ML Cancela. "Zebrafish model for the screening of drugs to rescue cdkl5 deficiency
disorder phenotypes". Paper presented in 2022 CDKL5 Forum, 2022.
- Tatiana Varela; Débora Varela; Conceição, Natércia; M Leonor Cancela. "cdkl5 mutant zebrafish recapitulates key phenotypes
of CDKL5 deficiency disorder". Paper presented in ABC Days – V Annual Meeting of the Algarve Biomedical Center, 2022.
- M Vitorino; Conceição, Natércia; D Varela; Tiscornia, Gustavo; ML Cancela. "The use of Acomys cahirinus to study the role
of Matrix Gla Protein in regeneration". Paper presented in INTEC kick-off meeting, 2022.
- Simão, Márcio; Conceição, Natércia; Leonor Cancela. "Impact of Lab-it to consolidate molecular genetics concepts in high schools
within the context of Biomedical sciences". Paper presented in III International Meeting of the Portuguese Society of Genetics,
2022.
- Tatiana Varela; Débora Varela; Conceição, Natércia; M Leonor Cancela. "Zebrafish: a promising animal model to study CDKL5
deficiency disorder". Paper presented in 11th European Conference on Rare Diseases & Orphan Products, 2022.
- M Vitorino; Conceição, Natércia; D Varela; G Tiscornia; ML Cancela. "Is MGP involved in Acomys cahirinus ear regeneration?".
Paper presented in III International Meeting of the Portuguese Society of Genetics, 2022.
- JMA Santos; RCR Abreu; C Rodrigues; I Borges; Conceição, Natércia; Gavaia, PJ; Laizé, Vincent; ML Cancela. "Zebrafish model
to study mechanisms of ectopic mineralization associated to elastinopathies.". Paper presented in III International Meeting
of the Portuguese Society of Genetics, 2022.
- Tatiana Varela; Débora Varela; Conceição, Natércia; M Leonor Cancela. "Involvement of cdkl5 gene during osteoblast proliferation
and differentiation.". Paper presented in Ciência 2022 ¿ Encontro com a Ciência e Tecnologia em Portugal, 2022.
- Tatiana Varela; Gil Martins; Débora Varela; Conceição, Natércia; M Leonor Cancela. Corresponding author: Tatiana Varela. "Characterization
of zebrafish cdkl5 knockdown using a morpholino approach". Paper presented in XXI National Congress of Biochemistry,
2021.
- Joana Rosa; Alessio Carletti; Tatiana Varela; Gavaia, Paulo; M Leonor Cancela; Vincent Laizé. Corresponding author: Joana
Rosa. "Identification and evaluation of marine osteogenic extracts using a zebrafish screening pipeline". Paper presented
in XII European Conference on Marine Natural Products, 2021.
- Débora Varela; J Zortéa; J Rosa; A Nunes; Conceição, Natércia; ML Cancela. "Functionality of binding sites for bone-related
transcription factors overlapping CpG sites on ZNF687, a gene associated with Paget’s disease of bone". Paper presented in
International Meeting of the Portuguese Society of Genetics, 2020.
- Tatiana Varela; G Martins; Débora Varela; M Vitorino; Conceição, Natércia; ML Cancela. "Contribution to validate zebrafish
as model for CDKL5 deficiency disorder using a morpholino-mediated approach". Paper presented in International Meeting
of the Portuguese Society of Genetics, 2020.
- Tatiana Varela; IS Morais; A Nechaeva; ML Cancela; L Faísca; A Reis; Conceição, Natércia. "Study of the candidate gene KIAA0319
for dyslexia in the Portuguese population". Paper presented in International Meeting of the Portuguese Society of Genetics,
2020.
- AS Alfaia; Conceição, Natércia; G Sequeira; P Carvalho; V Teixeira; C Ribeiro; ML Cancela. "Genetic analysis of Optineurin
and APEX variants in two families from south-center of Portugal with Paget Disease of Bone history". Paper presented in International
Meeting of the Portuguese Society of Genetics, 2020.
- H Caiado; Conceição, Natércia; ML Cancela. "Regulation of Matrix Gla Protein gene through epigenetic mechanisms in Bladder
Cancer". Paper presented in International Meeting of the Portuguese Society of Genetics, 2020.
- H Caiado; Conceição, Natércia; D Tiago; A Marreiros; AM Vaz; A Antunes; H Guerreiro; P Caldeira; ML Cancela. "MGP, FGF2 and
RUNX2 as important predictor factors to differentiate colorectal adenocarcinoma prognosis amongst patients". Paper presented
in International Meeting of the Portuguese Society of Genetics, 2020.
- AIM Marques; I Meirinho; J Mustacová; AI Favinha; EG Dimou; ALC Figueiredo; D Shkabura; et al. "Danio rerio as a model to
study ERCC1 function in bone formation". Paper presented in International Meeting of the Portuguese Society of Genetics,
2020.
- Débora Varela; Tatiana Varela; P Azevedo; A Ferreira; A.Silva; Nuno Marques; A Camacho; et al. "Two novel TBX5 mutations in
Holt-Oram syndrome patients with different clinical manifestations". Paper presented in International Meeting of the Portuguese
Society of Genetics, 2020.
- Débora Varela; Tatiana Varela; J Rosa; A Nunes; Conceição, Natércia; ML Cancela. "The effect of thalidomide on phenotype and
gene expression in zebrafish". Paper presented in International Meeting of the Portuguese Society of Genetics, 2020.
- Felício, Daniela; António Camacho; ML Cancela; Simão, Márcio. "Identification and characterization of polymorphisms in HLA-B*27
allele in ankylosing spondylitis patients". Paper presented in 1st International Meeting of the Portuguese Society of Genetics,
2020.
- Tatiana Varela; Martins, Gil; Débora Varela; Vitorino, Marta; Conceição, Natércia; M Leonor Cancela. "Contribution to validate
zebrafish as a model for CDKL5 deficiency disorder using a morpholino-mediated approach". Paper presented in International
Meeting of the Portuguese Society of Genetics, 2020.
- T Gago; H Caiado; Conceição, Natércia; D Tiago; AM Vaz; S Vicente; JL Enriquez; et al. "Expressão do gene MGP no Carcinoma
Colorretal: Haverá relação com o CA 19.9?". Paper presented in XXXIV Reunião Anual NGHD Núcleo de Gastroenterologia dos
Hospitais Distritais, 2019.
- Roberto, Vânia Palma; Martins, Gil; Dias, Jorge; Mata, Leonardo; Miguel, G.; M Leonor Cancela; Laizé, Vincent; Gavaia, P.
"Vitamin K role on the osteocalcin: GPRC6A axis: insights from non-mammalian models". Paper presented in European Calcified
Tissue Society 2019, 2019.
- H Caiado; Conceição, Natércia; ML Cancela. "Epigenetic regulation of Matrix Gla Protein gene through miR-155 in Breast Cancer".
Paper presented in 3rd jornadas do Algarve Biomedical Center, 2019.
- Tatiana Varela; M Vitorino; Conceição, Natércia; ML Cancela. "Zebrafish as a model to study CDKL5 deficiency disorder". Paper
presented in 3rd jornadas do Algarve Biomedical Center, 2019.
- Conceição, Natércia; Débora Varela; Tatiana Varela; P Azevedo; S. Pereira; A Camacho; I Jesus; ML Cancela. "Functional analysis
of a novel TBX5 c.905delA mutation present in a Holt-Oram syndrome patient". Paper presented in 3rd Jornadas do Algarve
Biomedical Center, 2019.
- Felício, Daniela; Camacho, António; ML Cancela; Simão, Márcio. "Bioinformatic analysis and characterization of pathogenic
mutations on HLA-B27 alleles and its putative implications on protein structure". Paper presented in 3rd Annual Meeting
of the Algarve Biomedical Center (ABC), 2019.
- Conceição, Natércia; Tatiana Varela; V Laizé; ML Cancela. "DUSP4 expression in colorectal cancer and insight into its transcriptional
regulation". Paper presented in VIII National RNA Meeting ptRNA2019, 2019.
- H Caiado; Conceição, Natércia; ML Cancela. "Correlation between Matrix Gla Protein gene and microRNA 155 expression in cancer".
Paper presented in VIII National RNA Meeting ptRNA2019, 2019.
- G Sequeira; P Carvalho; C Ribeiro; AS Alfaia; Conceição, Natércia; ML Cancela. "Characterization of Paget´s Disease of Bone
Patients from the South of Portugal (Algarve and Alentejo) – Clinical and Genetic Aspects". Paper presented in ACR/ARHP
Annual Meeting, 2018.
- H Caiado; R Reis; T Authier; ML Cancela; Conceição, Natércia. "Analysis of ZNF687 gene expression in different tumors using
the cancer genome atlas database". Paper presented in Annual Meeting 2018 Portuguese Society of Genetics, 2018.
- Conceição, Natércia; H Caiado; A Marreiros; ML Cancela. "Regulation of the Matrix Gla Protein through epigenetic mechanisms".
Paper presented in Annual Meeting 2018 Portuguese Society of Genetics, 2018.
- S Serrano; T Authier; ML Cancela; Conceição, Natércia. "Análise das regiões promotoras dos genes znf687a e znf687b do peixe-zebra
(Danio rerio)". Paper presented in Aniversário do curso de bioquímica, 2018.
- R arroja; T Authier; Conceição, Natércia; ML Cancela. "Estudo da análise do promotor do gene ZNF687 humano e identificação
de fatores de transcrição". Paper presented in Aniversário do curso de bioquímica, 2018.
- T Authier; S Serrano; AR Pinho; ML Cancela; Conceição, Natércia. "Study of transcriptional regulation of zebrafish orthologues
of human ZNF687 gene". Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, 5th Conference, 2018.
- W Zhang; HG Silva; C Viana; PJS Duarte; E Veiga; B Bica; I de Matos; et al. "Zebrafish as a model to study PHYH related pathologies".
Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, 5th Conference, 2018.
- Tatiana Varela; Conceição, Natércia; V Laizé; P Caldeira; A Marreiros; H Guerreiro; ML Cancela. "DUSP4 transcripts expression
as a potential biomarker for colorectal cancer". Paper presented in 2nd jornadas do Algarve Biomedical Center, 2018.
- Conceição, Natércia; Débora Varela; A Ferreira; N. Marques; AP Silva; ML Cancela. "Functional analysis of a novel TBX5 c.246_249delGATG
mutation present in a Holt-Oram syndrome patient". Paper presented in , 2nd jornadas do Algarve Biomedical Center,
2018.
- Conceição, Natércia; H Caiado; D Tiago; A Marreiros; AM Vaz; S Vicente; H Guerreiro; P Caldeira; ML Cancela. "MGP overexpression
is associated with a worse prognosis and survival outcome in colorectal adenocarcinomas". Paper presented in 2nd jornadas
do Algarve Biomedical Center, 2018.
- I Bodião; ML Cancela; Conceição, Natércia. "On using Feature Descriptors asScreening for detection of SNPs within the PDB6
locus associated with Paget disease of bone". Paper presented in 4th MEEting of MIM, 2018.
10.1049/ic.2016.0080
- T Authier; Conceição, Natércia; ML Cancela. "Comparative analysis of the zinc finger protein ZNF687 throughout evolution".
Paper presented in X Encontro Nacional de Biologia Evolutiva, 2017.
- ML Cancela; Débora Varela; Conceição, Natércia. "Initial validation of zebrafish as model for Holt-Oram syndrome". Paper presented
in FishBone 2017 ECTS 2017 Pre-congress, 2017.
- Diogo, Patricia; Eufrásio, Ana; Martins, Gil; Cardeira-da-Silva, João; M Leonor Cancela; Cabrita, Elsa; Gavaia, P. "Diabetic
zebrafish (Danio rerio) sperm quality and cryopreservation". Paper presented in 20th Annual European Society for Domestic
Animal Reproduction - ESDAR Conference, 2016.
- AS Sofia; S Mariano; Tatiana Varela; JJ Matos; D Varela; T Authier; ML Cancela; Conceição, Natércia. "Bioinformatic Analysis
of CCDC3 gene: A Potential Contributor for Paget Disease of Bone?". Paper presented in XL Jornadas Portuguesas de Genética,
2016.
- M Vitorino; Conceição, Natércia; ML Cancela. "Zebrafish as model for bone diseases associated with Rett syndrome". Paper presented
in XL Jornadas Portuguesas de Genética, 2016.
- C Fazenda; M Vitorino; A Cachucho; L Shu-Wha; PJ Gavaia; Conceição, Natércia; ML Cancela. "Gla-rich protein deficient mice
born from homozygous mutant progenitors show cartilage and bone defects". Paper presented in XL Jornadas Portuguesas de
Genética, 2016.
- VP Roberto; Conceição, Natércia; MJ Nunes; E. Rodrigues; ML Cancela; DM Tiago. "miR-214: A Novel Regulator of Chondrogenesis?".
Paper presented in ECST2016, 2016.
- IAL Silva; Conceição, Natércia; L Michou; ML Cancela. "Comparative analysis of human and zebrafish OPTN: molecular and evolutionary
perspectives". Paper presented in ECST2016, 2016.
- IAL Silva; Conceição, Natércia; ML Cancela. "OPTN and CCDC3 share a bidirectional promoter region that is regulated by NF-kB".
Paper presented in ECSC2016, 2016.
- Conceição, Natércia; Fazenda, Cindy; Martins, Gil; Gavaia, P; M Leonor Cancela. "Study of transcriptional regulation and function
of Gla rich protein gene in zebrafish". Paper presented in 9th European Zebrafish Meeting, 2015.
- Gavaia, P; Pereira, Alexandra; Grenha, Ana; Martins, Gil; Conceição, Luis E. C.; Rodrigues, Vera; Pinto, Wilson; M Leonor
Cancela; Dias, Jorge. "Dietary supplementation with strontium citrate positively affects the osteological development of zebrafish
(Danio rerio) larvae". Paper presented in 9th European Zebrafish Meeting, 2015.
- D Marques; Conceição, Natércia; ML Cancela. "Paget’s disease of bone: contribution to the study of human locus PDB6". Paper
presented in 1st MEEting of MIM, 2015.
- JC Nogueira; Conceição, Natércia; ML Cancela. "MRD20 or Mental Retardation Autosomal Dominant: contribution to the study of
a recently identified human mutation". Paper presented in 1st MEEting of MIM, 2015.
- IAL Silva; Conceição, Natércia; L Michou; ML Cancela. "Zebrafish as an animal model to study OPTN role in Paget´s disease
of bone". Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, 4th Conference, 2015.
- Conceição, Natércia; A Adrião; M Grazina; ML Cancela. "Towards validation of zebrafish as a model to study MEF2C related pathologies".
Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, 4th Conference, 2015.
10.1109/icstw.2016.7
- M Vitorino; Conceição, Natércia; A Adrião; ML Cancela. "Zebrafish as a model to study bone diseases associated with Rett syndrome".
Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, 4th Conference, 2015.
- Fazenda, Cindy; Martins, Gil; Gavaia, P; M Leonor Cancela; Conceição, Natércia. "Establishment of transgenic zebrafish lines
capable of conditionally inducing expression of Gla-rich protein". Paper presented in IV Interdisciplinary Approaches in
Fish Skeletal Biology, 2015.
- Gavaia, P; Martins, Gil; Livramento, Marcelo ; Laizé, Vincent; M Leonor Cancela; Dias, Jorge. "Effects of dietary zinc supplementation
on zebrafish larvae osteological development". Paper presented in IV Interdisciplinary Approaches in Fish Skeletal Biology,
2015.
- Pereira, Alexandra; Martins, Gil; Pinto, Wilson; Conceição, Luis E. C.; Dias, Jorge; M Leonor Cancela; Gavaia, P. "Effects
of dietary supplementation with strontium nitrate on the osteological development of zebrafish (Danio rerio) larvae". Paper
presented in IV Interdisciplinary Approaches in Fish Skeletal Biology, 2015.
- Gavaia, P; Bretes, Francisco; Martins, Gil; Conceição, Luis E. C.; Pinto, Wilson; M Leonor Cancela; Dias, Jorge. "Osteological
and developmental effects of dietary zinc supplementation in zebrafish larvae". Paper presented in Aquaculture Europe 2014,
2014.
- IAL Silva; Conceição, Natércia; L Michou; ML Cancela. "Functional study of Optineurin (OPTN) variants associated with Paget’s
disease of bone". Paper presented in ASBMR, 2014.
- C Fazenda; Conceição, Natércia; ML Cancela. "Transcription factors from Sox family regulate zebrafish Gla-rich protein 2 gene".
Paper presented in YSF FEBS2014, 2014.
- IAL Silva; Conceição, Natércia; L Michou; ML Cancela. "Functional analysis of a promoter polymorphism of Optineurin, a gene
to associated to Paget’s Disease of Bone". Paper presented in ECTS2014, 2014.
- Conceição, Natércia; A Adrião; ML Cancela. "Identification of two functional promoters for zebrafish mef2cb gene". Paper presented
in 8th European Zebrafish Meeting, 2013.
- C Fazenda; Conceição, Natércia; ML Cancela. "Transcriptional regulation of the zebrafish Gla-rich protein 2 (grp2) gene".
Paper presented in Workshop - Interdisciplinary Approaches in Fish Skeletal Biology, 2013.
- IAL Silva; Conceição, Natércia; L Michou; ML Cancela. "Single nucleotide polymorphisms identification and functional analysis
in PDB6 locus – A target locus for Paget’s Disease of Bone". Paper presented in ECTS2013, 2013.
- Conceição, Natércia; B Simões; ML Cancela. "Functional analysis of the two Runx3 promoters in osseous and non-osseous cells:
implications for tissue/differentiation specific transcription of distinct isoforms". Paper presented in ECST2013,
2013.
- A Adrião; PJ Gavaia; Conceição, Natércia; ML Cancela. "Use of reporter lines to visualize bone and cartilage phenotypes in
the zebrafish mef2cab1086 mutant line". Paper presented in Workshop - Interdisciplinary Approaches in Fish Skeletal Biology,
2013.
- B Simões; Conceição, Natércia; RN Kelsh; ML Cancela. "Identification and in vitro/in vivo functional characterization of zebrafish
runx3 alternative promoters". Paper presented in FEBS International Workshop “New Developments in RNA Biology", 2012.
- D Tiago; Conceição, Natércia; V Laizé; ML Cancela. "Evidences for post-transcriptional regulation of MGP: can microRNAs regulate
tissue calcification?". Paper presented in FEBS International Workshop “New Developments in RNA Biology", 2012.
10.1158/1538-7445.fbcr13-ia5
- AP Gandolfo; IAL Silva; ML Cancela; Conceição, Natércia. "Zebrafish: a good model to study XPG pathologies?". Paper presented
in XXXVII JPG Congress, 2012.
10.1158/1538-7445.am2017-804
- IAL Silva; R Leite; ML Cancela; Conceição, Natércia. "TFIIH is remarkably conserved between zebrafish and human". Paper presented
in 5Th Clinical Biochemistry Workshop, 2012.
- A Adrião; Conceição, Natércia; IAL Silva; M Grazina; ML Cancela. "Validation of zebrafish as a model to study mef2c pathologies".
Paper presented in 5Th Clinical Biochemistry Workshop, 2012.
- A Adrião; Conceição, Natércia; M Grazina; ML Cancela. "Expression, regulation and interaction with target genes in health
and disease". Paper presented in DCBM Ph.D. student seminars, 2011.
- Gavaia, Paulo J.; Dionísio, G.; Conceição, L. E. C.; Hamre, K.; Cancela, Leonor. "Effects of phylloquinone on Solea senegalensis
skeletogenesis". Paper presented in World Aquaculture 2011- Aquaculture for a changing world. June 6-10 2011, Natal convention
center, Natal, Brazil., 2011.
- Dias, J.; Rodrigues, V.; Colen, Rita; Rosa, Joana; Viegas, M. N.; Cardeira, J.; Cancela, Leonor; Gavaia, Paulo J.; Laizé,
Vincent. "Dietary lipid quality regulates bone composition and metabolism in gilthead seabream (Sparus aurata) juveniles".
Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, April 26-28, Tavira, Portugal., 2011.
- C Fazenda; ML Cancela; Conceição, Natércia. "Molecular characterization and expression of a novel Gla-containing protein,
Gla-rich protein (Grp), in zebrafish". Paper presented in Workshop - Interdisciplinary Approaches in Fish Skeletal Biology,
2011.
- IAL Silva; ML Cancela; Conceição, Natércia. "xpd mutations in zebrafish: is there a bone phenotype?". Paper presented in Workshop
- Interdisciplinary Approaches in Fish Skeletal Biology, 2011.
- Dionísio, G.; Cancela, Leonor; Gavaia, Paulo J.. "Effect of dietary vitamin K supplementation on skeletal development of Danio
rerio". Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, April 26-28, Tavira, Portugal., 2011.
- Dionísio, G.; Bensimon-Brito, A.; Gavaia, Paulo J.; Cancela, Leonor. "Effect of warfarin in zebrafish (Danio rerio) bone formation
during caudal fin regeneration". Paper presented in Interdisciplinary Approaches in Fish Skeletal Biology, April 26-28,
Tavira, Portugal., 2011.
- Gavaia, Paulo J.; Nicolau, L.; Cancela, Leonor; Pousão-Ferreira, P.. "Early osteological development and deformities of Diplodus
sargus (Linnaeus, 1758) and Diplodus vulgaris (Saint-Hillaire, 1817)". Paper presented in Interdisciplinary Approaches
in Fish Skeletal Biology, April 26-28, Tavira, Portugal., 2011.
- Valles, E.; Cardeira, J.; Dionísio, G.; Estévez, A.; Pousão-Ferreira, P.; Cancela, Leonor; Gavaia, Paulo J.. "Early axial
and appendicular skeletal development of the meagre (Argyrosomus regius). A comparison of two rearing systems". Paper presented
in Interdisciplinary Approaches in Fish Skeletal Biology, April 26-28, Tavira, Portugal., 2011.
- Gavaia, Paulo J.; Dionísio, G.; Campos, C.; Carvalho, A. P.; Conceição, L. E. C.; Cancela, Leonor. "Temperature affects skeletogenesis
during Senegalese sole (Solea senegalensis, Kaup) larval development". Paper presented in Interdisciplinary Approaches
in Fish Skeletal Biology, April 26-28, Tavira, Portugal., 2011.
- Gavaia, Paulo J.; Dionísio, G.; Cardeira, J.; Cunha, M. E.; Pousão-Ferreira, P.; Conceição, L. E. C.; Cancela, Leonor. "Skeletal
quality in Senegalese sole: characterization of fish resulting from environmental and nutritional trials". Paper presented
in Workshop Cultivation of soles, 2011.
- C Fazenda; Conceição, Natércia; ML Cancela. "Identification of two isoforms of Gla Rich Protein (GRP) in zebrafish and its
molecular characterization". Paper presented in XVII National Congress of Biochemistry, 2010.
10.1158/1538-7445.am2011-3895
- B Simões; Conceição, Natércia; R Kelsh; ML Cancela. "runx3 promoter analysis and expression patterns in tissues and during
development of zebrafish". Paper presented in XVII National Congress of Biochemistry, 2010.
- IAL Silva; C Fazenda; Conceição, Natércia; ML Cancela. "Study of the Xeroderma pigmentosum D (XPD) expression in zebrafish".
Paper presented in XVII National Congress of Biochemistry, 2010.
- C Fazenda; Conceição, Natércia; ML Cancela. "Molecular characterization of gla rich protein (GRP) gene expression and function
using zebrafish as model system". Paper presented in Biomedical Sciences Ph.D. students seminars, 2010.
- M Sousa; C Fazenda; Conceição, Natércia; ML Cancela. "Matrix Gla Protein is a target gene for transcription factor MEF2C".
Paper presented in Science Meeting 2010, 2010.
- Conceição, Natércia; A Lelo; JP Pinto; ML Cancela. "Regulation of hepcidin expression: in silico promoter analysis". Paper
presented in SINAL 2010, 2010.
- Conceição, Natércia; C Fazenda; C Viegas; R Leite; ML Cancela. "Promoter analysis of cartilage-expressed genes". Paper presented
in 4Th Clinical Biochemistry Workshop, 2010.
- B Simões; Conceição, Natércia; ML Cancela; RN Kelsh. "Investigation of runx3 expression pattern and function in zebrafish
peripheral nervous system development". Paper presented in 6th European Zebrafish Genetics and Development Meeting,
2009.
- C Fazenda; CSB Viegas; Conceição, Natércia; DC Simes; ML Cancela. "Development of molecular and cellular tools to study the
function of skeletal Gla-containing proteins in sturgeon". Paper presented in Workshop - Interdisciplinary Approaches in
Fish Skeletal Biology, 2009.
- Conceição, Natércia; C Cox; B Simões; M Viegas; ML Cancela. "Comparative promoter analysis and its application in analysis
of cartilage-expressed genes regulation". Paper presented in Workshop - Interdisciplinary Approaches in Fish Skeletal Biology,
2009.
- B Simões; D Rodrigues; Conceição, Natércia; RN Kelsh; ML Cancela. "Spatial-temporal expression of Runx3 during early zebrafish
development and in silico and in vitro analysis of its promoter regions". Paper presented in XVIth National Congress of
Biochemistry, 2008.
- Conceição, Natércia; C Cox; B Simões; M Viegas; ML Cancela. "Computational identification of regulatory motifs in cartilage-expressed
genes using zebrafish as an in vivo model". Paper presented in XVIth National Congress of Biochemistry, 2008.
- C Fazenda; Conceição, Natércia; ML Cancela. "Possible regulation of the matrix gla protein gene by the transcription factor
mef2c". Paper presented in XVIth National Congress of Biochemistry, 2008.
- Conceição, Natércia; C Fazenda; B Simões; ML Cancela. "Transcriptional regulation of the Xenopus laevis Matrix Gla Protein
gene expression". Paper presented in 35th European Symposium on Calcified Tissues, 2008.
- Conceição, Natércia; V Laizé; ML Cancela. "Regulation of Matrix Gla Protein gene expression in teleost fish sparus aurata".
Paper presented in MGE - Marine Genomics Europe Final Assembly, 2008.
- Conceição, Natércia; B Simões; ML Cancela; RN Kelsh. "runx3 structure and function in zebrafish neural crest: expression pattern
and morpholino knockdown". Paper presented in Seminários de Mar e Ambiente 2008, 2008.
- Conceição, Natércia; C Fazenda; B Simões; ML Cancela. "Identification of a new Runx2 isoform in Xenopus laevis: molecular
organization, tissue distribution and effect on MGP gene transcription". Paper presented in MICRO’07 BIOTEC’07-XXXIII JPG
Congress, 2007.
- M Viegas; Conceição, Natércia; J Fidalgo; ML Cancela. "Characterization of a Xenopus laevis bone derived cell line, X1, capable
of mineralizing in vitro". Paper presented in MICRO’07 BIOTEC’07-XXXIII JPG Congress, 2007.
- Conceição, Natércia; C Fazenda; B Simões; ML Cancela. "Identification of new Runx2 isoforms from Xenopus laevis capable of
inducing MGP gene expression in vitro". Paper presented in IVth National RNA Meeting, 2007.
- B Simões; Conceição, Natércia; J Belo; ML Cancela. "Analysis of Xenopus laevis MGP knockdown phenotype: expression pattern
of developmental marker genes". Paper presented in IVth National RNA Meeting, 2007.
- B Simões; Conceição, Natércia; ML Cancela; RN Kelsh. "Effects of Runx3 isoforms on distribution and migration of zebrafish
neural crest cells". Paper presented in Workshop “Mechanisms of early development: cell fate determination, morphogenesis
and patterning, 2007.
- B Simões; A.Silva; M Vitorino; Conceição, Natércia; J Belo; ML Cancela. "Spatio-temporal pattern of expression and regulation
of matrix Gla protein (MGP) during early development in Xenopus laevis". Paper presented in 32rd FEBS Congress, 2007.
10.1109/icpr.2008.4761009
- Conceição, Natércia; B Simões; C Fazenda; ML Cancela. "Runx2-mediated regulation of the Matrix Gla Protein gene". Paper presented
in 32rd FEBS Congress, 2007.
- B Simões; A.Silva; Conceição, Natércia; M Vitorino; J. Belo; ML Cancela. "Spatial-temporal pattern of expression and regulation
of matrix Gla protein (MGP) during early development in Xenopus laevis". Paper presented in XV National Congress of Biochemistry,
2006.
- Conceição, Natércia; J Fidalgo; B Simões; ML Cancela. "Regulation of the Xenopus laevis MGP promoters by transcription factors:
NF-AT and Runx2". Paper presented in Workshop Mineralised tissue formation, regeneration, and repair, 2006.
- Conceição, Natércia; A.Silva; B Simões; J. Belo; ML Cancela. ", Mapping of the cis-regulatory elements in the XlMGP promoters
by cell culture experiments and microinjection of Xenopus laevis embryos using deletion mutant constructs". Paper presented
in 4th Meeting of the Centre of Marine and Environmental Investigation, 2006.
- AR Pombinho; V Laizé; Conceição, Natércia; ML Cancela. "Regulators of MGP gene expression in Sparus aurata VSa13 bone-derived
cell line". Paper presented in Seminários “Mar e Ambiente”, 2006.
- B Simões; Conceição, Natércia; CSB Viegas; JP Pinto; P Gavaia; RN Kelsh; ML Cancela. "Gene structure, Runx2-dependent regulation
and spatial-temporal expression of collagen X¿1 during early zebrafish development". Paper presented in Microscopy in Motion
- XLth Meeting of the SPME-BC, 2005.
- JP Pinto; Conceição, Natércia; CSB Viegas; RB Leite; RN Kelsh; ML Cancela. "Identification of a new pebp2¿A2 isoform from
zebrafish runx2 capable of inducing osteocalcin gene expression in vitro". Paper presented in XIV National Congress of
Biochemistry, 2004.
- J Fidalgo; Conceição, Natércia; J Pinto; ML Cancela. "Hormonal regulation of Matrix Gla Protein expression in a Xenopus laevis
bone-derived cell culture". Paper presented in XIV National Congress of Biochemistry, 2004.
- AR Pombinho; V Laizé; Conceição, Natércia; ML Cancela. "Regulation of matrix Gla protein gene expression in a fish bone-derived
cell line". Paper presented in XIV National Congress of Biochemistry, 2004.
- B Simões; Conceição, Natércia; CSB Viegas; JP Pinto; ML Cancela. "Molecular cloning of the zebrafish (Danio rerio) Collagen
Xalpha1 cDNA and gene. Identification of promoter regulatory elements". Paper presented in XIV National Congress of Biochemistry,
2004.
10.1063/1.5000196
- JP Pinto; Conceição, Natércia; PJ Gavaia; ML Cancela. "Co-localization of Matrix Gla protein gene expression and protein accumulation
with cartilage distribution in the teleost fish Sparus aurata". Paper presented in XIII National Congress of Biochemistry,
2002.
- J Fidalgo; Conceição, Natércia; JP Pinto; ML Cancela. "Retinoic acid induction of matrix Gla protein expression in a Xenopus
laevis bone derived cell line". Paper presented in XIII National Congress of Biochemistry, 2002.
- Conceição, Natércia; R Schule; ML Cancela. "Characterization of the 5´flanking region of the Xenopus laevis matrix Gla protein
(MGP) gene". Paper presented in 27th FEBS/PABMB Meeting, 2001.
- ML Cancela; DC Simes; P Rodrigues; Conceição, Natércia; JP Reia; MK Williamson; PA Price. "Expression of Matrix Gla Protein
(MGP) in fish and amphibian: a model system to study the evolution of MGP function". Paper presented in ASBMR 22st Annual
Meeting, Metro Toronto Convention Centre, 2000.
- Conceição, Natércia; M Ohresser; N Henriques; Prof. Dr. Roland Schule; ML Cancela. "Molecular cloning and regulation of the
Xenopus laevis Matrix Gla protein gene". Paper presented in ASBMR 21st Annual Meeting, 1999.
- Conceição, Natércia; NM Henriques; M Ohresser; ML Cancela. "Characterization of Matrix Gla protein (MGP) gene from Xenopus
laevis (Daudin, 1802)". Paper presented in XI National Congress of Biochemistry, 1998.
|
| Journal article |
- ML Cancela; Conceicao, Natercia; Caiado, H.. Corresponding author: Conceicao, Natercia. "Transcriptional regulation of the
human MGP promoter: identification of downstream repressors". Int. J. Mol. Sci. 25 (2024): 12597.
Published
- Helena Caiado; M. Leonor Cancela; Natércia Conceição. "Transcriptional Regulation of the Human MGP Promoter: Identification
of Downstream Repressors". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms252312597.
10.3390/ijms252312597
- Carletti, Alessio; Gavaia, Paulo Jorge; Cancela, Maria Leonor; Laizé, Vincent. "Metabolic bone disorders and the promise of
marine osteoactive compounds". Cellular and Molecular Life Sciences 81 1 (2024): http://dx.doi.org/10.1007/s00018-023-05033-x.
10.1007/s00018-023-05033-x
- Carletti, Alessio; Rosa, Joana T.; Pes, Katia; Borges, Inês; Santos, Tamára; Barreira, Luísa; Varela, João; et al. "The osteogenic
and mineralogenic potential of the microalgae Skeletonema costatum and Tetraselmis striata CTP4 in fish models". Cellular
and Molecular Life Sciences 80 10 (2023): http://dx.doi.org/10.1007/s00018-023-04953-y.
Open access • Published • 10.1007/s00018-023-04953-y
- Adrião, Andreia; Mariano, Sara; Mariano, José; Gavaia, Paulo J.; Cancela, M. Leonor; Vitorino, Marta; Conceição, Natércia.
"mef2ca and mef2cb Double Mutant Zebrafish Show Altered Craniofacial Phenotype and Motor Behaviour". Biomolecules 13
5 (2023): 805. http://dx.doi.org/10.3390/biom13050805.
Published • 10.3390/biom13050805
- Saavedra, Carlos; Milan, Massimo; Leite, Ricardo B.; Cordero, David; Patarnello, Tomaso; Cancela, M. Leonor; Bargelloni, Luca.
"Transcriptional Profiling of Populations in the Clam Ruditapes decussatus Suggests Genetically Determined Differentiation
in Gene Expression along Parallel Temperature Gradients and between Races of the Atlantic Ocean and West Mediterranean Sea".
Fishes 8 4 (2023): 203. http://dx.doi.org/10.3390/fishes8040203.
Open access • Published • 10.3390/fishes8040203
- Santos, João M. A.; Laizé, Vincent; Gavaia, Paulo J.; Conceição, Natércia; Cancela, M. Leonor. "Zebrafish Models to Study
Ectopic Calcification and Calcium-Associated Pathologies". International Journal of Molecular Sciences 24 4 (2023):
3366. http://dx.doi.org/10.3390/ijms24043366.
Open access • Published • 10.3390/ijms24043366
- Varela, Débora; Varela, Tatiana; Conceição, Natércia; Cancela, M. Leonor. "Regulation of human ZNF687, a gene associated with
Paget's disease of bone". The International Journal of Biochemistry & Cell Biology 154 (2023): 106332. http://dx.doi.org/10.1016/j.biocel.2022.106332.
10.1016/j.biocel.2022.106332
- Poudel, Sunil; Martins, Gil; Cancela, M. Leonor; Gavaia, Paulo J.. "Resveratrol-Mediated Reversal of Doxorubicin-Induced Osteoclast
Differentiation". International Journal of Molecular Sciences 23 23 (2022): 15160. http://dx.doi.org/10.3390/ijms232315160.
Published • 10.3390/ijms232315160
- Cardeira-da-Silva, João; Bensimon-Brito, Anabela; Tarasco, Marco; Brandão, Ana S.; Rosa, Joana T.; Borbinha, Jorge; Almeida,
Paulo J.; et al. "Fin ray branching is defined by TRAP+ osteolytic tubules in zebrafish". Proceedings of the National Academy
of Sciences 119 48 (2022): http://dx.doi.org/10.1073/pnas.2209231119.
Open access • Published • 10.1073/pnas.2209231119
- Sunil Poudel; Gil Martins; M. Leonor Cancela; Paulo J. Gavaia. "Regular Supplementation with Antioxidants Rescues Doxorubicin-Induced
Bone Deformities and Mineralization Delay in Zebrafish". Nutrients (2022): https://doi.org/10.3390/nu14234959.
10.3390/nu14234959
- Silva, Iris A.L.; Varela, Débora; Cancela, M. Leonor; Conceição, Natércia. "Zebrafish optineurin: genomic organization and
transcription regulation". Genome 65 10 (2022): 513-523. http://dx.doi.org/10.1139/gen-2022-0019.
Open access • 10.1139/gen-2022-0019
- Tarasco, Marco; Gavaia, Paulo J.; Bensimon-Brito, Anabela; Cordelières, Fabrice P.; Santos, Tamára; Martins, Gil; de Castro,
Daniela T.; et al. "Effects of pristine or contaminated polyethylene microplastics on zebrafish development". Chemosphere
303 (2022): 135198. http://dx.doi.org/10.1016/j.chemosphere.2022.135198.
Published • 10.1016/j.chemosphere.2022.135198
- Joana T. Rosa; Marco Tarasco; Paulo J. Gavaia; M. Leonor Cancela; Vincent Laizé. "Screening of Mineralogenic and Osteogenic
Compounds in Zebrafish—Tools to Improve Assay Throughput and Data Accuracy". Pharmaceuticals (2022): https://doi.org/10.3390/ph15080983.
10.3390/ph15080983
- Márcio Simão; Natércia Conceição; Susana Imaginário; João Amaro; Maria Leonor Cancela. "Lab-It Is Taking Molecular Genetics
to School". BioChem (2022): https://doi.org/10.3390/biochem2020011.
10.3390/biochem2020011
- Varela, Tatiana; Varela, Débora; Martins, Gil; Conceição, Natércia; Cancela, M. Leonor. "Cdkl5 mutant zebrafish shows skeletal
and neuronal alterations mimicking human CDKL5 deficiency disorder". Scientific Reports 12 1 (2022): http://dx.doi.org/10.1038/s41598-022-13364-1.
Open access • Published • 10.1038/s41598-022-13364-1
- Carletti, Alessio; Cardoso, Carlos; Lobo-Arteaga, Jorge; Sales, Sabrina; Juliao, Diana; Ferreira, Inês; Chainho, Paula; et
al. "Antioxidant and Anti-inflammatory Extracts From Sea Cucumbers and Tunicates Induce a Pro-osteogenic Effect in Zebrafish
Larvae". Frontiers in Nutrition 9 (2022): 888360. http://dx.doi.org/10.3389/fnut.2022.888360.
Open access • Published • 10.3389/fnut.2022.888360
- Adrião, Andreia; Santana, Isabel; Ribeiro, Carolina; Cancela, M. Leonor; Conceição, Natércia; Grazina, Manuela. "Identification
of a novel mutation in MEF2C gene in an atypical patient with frontotemporal lobar degeneration". Neurological Sciences
43 1 (2022): 319-326. http://dx.doi.org/10.1007/s10072-021-05269-0.
Open access • Published • 10.1007/s10072-021-05269-0
- Poudel, Sunil; Izquierdo M; Leonor Cancela; Gavaia, P; Sunil Poudel; Marisol Izquierdo; Maria Leonor Cancela; Paulo J. Gavaia.
"Reversal of Doxorubicin-induced bone loss and mineralization by supplementation of Resveratrol and MitoTEMPO in the early
development of Sparus aurata.". Nutrients 14 6 (2022): 1154-1154. https://doi.org/10.3390/nu14061154.
Open access • Published • 10.3390/nu14061154
- Tarasco, Marco; Gavaia, Paulo J.; Bensimon-Brito, Anabela; Cardeira-da-Silva, João; Ramkumar, Srinath; Cordelières, Fabrice
P.; Günther, Stefan; et al. "New insights into benzo[¿]pyrene osteotoxicity in zebrafish". Ecotoxicology and Environmental
Safety 226 (2021): 112838. http://dx.doi.org/10.1016/j.ecoenv.2021.112838.
Published • 10.1016/j.ecoenv.2021.112838
- Roberto, Vânia P.; Surget, Gwladys; Le Lann, Klervi; Mira, Sara; Tarasco, Marco; Guérard, Fabienne; Poupart, Nathalie; et
al. Corresponding author: Cancela, M. Leonor. "Antioxidant, Mineralogenic and Osteogenic Activities of Spartina alterniflora
and Salicornia fragilis Extracts Rich in Polyphenols". Frontiers in Nutrition 8 (2021): 719438.. http://dx.doi.org/10.3389/fnut.2021.719438.
Open access • Published • 10.3389/fnut.2021.719438
- Varela, Tatiana; Conceição, Natércia; Laizé, Vincent; Cancela, M. Leonor. Corresponding author: Cancela, M. Leonor. "Transcriptional
regulation of human
DUSP4
gene by cancer-related transcription factors". Journal of Cellular Biochemistry 122 10 (2021): 1556-1566. http://dx.doi.org/10.1002/jcb.30078.
Open access • Published • 10.1002/jcb.30078
- Rosa, Joana T.; Laizé, Vincent; Gavaia, Paulo J.; Cancela, M. Leonor. "Fish Models of Induced Osteoporosis". Frontiers
in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.672424.
Published • 10.3389/fcell.2021.672424
- Simão, Márcio; Cancela, M. Leonor. "Musculoskeletal complications associated with pathological iron toxicity and its molecular
mechanisms". Biochemical Society Transactions 49 2 (2021): 747-759. http://dx.doi.org/10.1042/bst20200672.
Open access • Published • 10.1042/bst20200672
- Kempf, Hervé; Murshed, Monzur; ML Cancela; Laizé, V; Conceiçao, Natercia. "Keutel Syndrome, a Review of 50 Years of Literature".
Frontiers in Cell and Developmental Biology 9 642136 (2021): 275-283. http://dx.doi.org/10.3389/fcell.2021.642136.
Open access • Published • 10.3389/fcell.2021.642136
- Varela, Débora; Varela, Tatiana; Conceição, Natércia; Ferreira, Ângela; Marques, Nuno; Silva, Ana Paula; Azevedo, Pedro; et
al. Corresponding author: Cancela, M. Leonor. "Functional analysis of two novel TBX5 variants present in individuals with
Holt Oram syndrome with different clinical manifestations". Molecular Genetics and Genomics 296 4 (2021): 809-821.
http://dx.doi.org/10.1007/s00438-021-01781-2.
Open access • Published • 10.1007/s00438-021-01781-2
- Rosa, Joana; Carletti, Alessio; Varela, Tatiana; Gavaia, Paulo J.; Cancela, M. Leonor; Laizé, Vincent. "Identification of
bone anabolic compounds of marine origin using a zebrafish pipeline". Bone Reports 14 (2021): 100985. http://dx.doi.org/10.1016/j.bonr.2021.100985.
Open access • Published • 10.1016/j.bonr.2021.100985
- Poudel, Sunil; Izquierdo, Marisol; Cancela, M. Leonor; Gavaia, Paulo J.. "Reversal of Doxorubicin-induced bone loss by antioxidant
supplement". Bone Reports 14 (2021): 100984. http://dx.doi.org/10.1016/j.bonr.2021.100984.
Open access • Published • 10.1016/j.bonr.2021.100984
- Rotter, Ana; Barbier, Michéle; Bertoni, Francesco; Bones, Atle M.; Cancela, M. Leonor; Carlsson, Jens; Carvalho, Maria F.;
et al. "The Essentials of Marine Biotechnology". Frontiers in Marine Science 8 (2021): http://dx.doi.org/10.3389/fmars.2021.629629.
Open access • Published • 10.3389/fmars.2021.629629
- Varela, Débora; Conceição, Natércia; Cancela, M. Leonor. Corresponding author: Cancela, M. Leonor. "Transcriptional regulation
of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors". Gene 768 (2021): 145322. http://dx.doi.org/10.1016/j.gene.2020.145322.
Open access • Published • 10.1016/j.gene.2020.145322
- Cancela, M Leonor; Conceiçao, Natercia; Varela, Tatiana; Laizé, V. "A expressão dos transcritos do gene DUSP4 como potencial
biomarcador no cancro colorretal.". UALGORITMO 3 (2021): 25-28.
Published
- Simão, Márcio; Leite, Ricardo B.; Cancela, M. Leonor. "Expression of four new ferritins from grooved carpet shell clam Ruditapes
decussatus challenged with Perkinsus olseni and metals (Cd, Cu and Zn)". Aquatic Toxicology 229 (2020): 105675. http://dx.doi.org/10.1016/j.aquatox.2020.105675.
Published • 10.1016/j.aquatox.2020.105675
- Shea, M. Kyla; Booth, Sarah L.; Harshman, Stephanie G.; Smith, Donald; Carlson, Cathy S.; Harper, Lindsey; Armstrong, Alexandra
R.; et al. "The effect of vitamin K insufficiency on histological and structural properties of knee joints in aging mice".
Osteoarthritis and Cartilage Open 2 3 (2020): 100078. http://dx.doi.org/10.1016/j.ocarto.2020.100078.
Published • 10.1016/j.ocarto.2020.100078
- Tarasco, Marco; Cordelières, Fabrice P.; Cancela, M. Leonor; Laizé, Vincent. "ZFBONE: An ImageJ toolset for semi-automatic
analysis of zebrafish bone structures". Bone 138 (2020): 115480. http://dx.doi.org/10.1016/j.bone.2020.115480.
Published • 10.1016/j.bone.2020.115480
- Caiado, Helena; Conceição, Natércia; Tiago, Daniel; Marreiros, Ana; Vicente, Susana; Enriquez, Jose Luis; Vaz, Ana Margarida;
et al. "Data on the evaluation of FGF2 gene expression in Colorectal Cancer". Data in Brief 31 (2020): 105765. http://dx.doi.org/10.1016/j.dib.2020.105765.
Published • 10.1016/j.dib.2020.105765
- Varela, Tatiana; Laizé, Vincent; Conceição, Natércia; Caldeira, Paulo; Marreiros, Ana; Guerreiro, Horácio; Cancela, M Leonor.
"Expression of DUSP4 transcript variants as a potential biomarker for colorectal cancer". Biomarkers in Medicine 14
8 (2020): 639-650. http://dx.doi.org/10.2217/bmm-2019-0369.
Published • 10.2217/bmm-2019-0369
- Rotter, Ana; Bacu, Ariola; Barbier, Michèle; Bertoni, Francesco; Bones, Atle M.; Cancela, M. Leonor; Carlsson, Jens; et al.
"A New Network for the Advancement of Marine Biotechnology in Europe and Beyond". Frontiers in Marine Science 7 278
(2020): http://dx.doi.org/10.3389/fmars.2020.00278.
Open access • Published • 10.3389/fmars.2020.00278
- Vijayakumar, Parameswaran; Cardeira, João; Laizé, Vincent; Gavaia, Paulo J.; Cancela, M. Leonor. "Cells Isolated from Regenerating
Caudal Fin of Sparus aurata Can Differentiate into Distinct Bone Cell Lineages". Marine Biotechnology 22 3 (2020):
333-347. http://dx.doi.org/10.1007/s10126-019-09937-3.
Published • 10.1007/s10126-019-09937-3
- Tarasco, Marco; Martins, Gil; Gavaia, Paulo J.; Bebianno, Maria J.; Cancela, M. Leonor; Laizé, Vincent. "ZEB316: A Small Stand-Alone
Housing System to Study Microplastics in Small Teleosts". Zebrafish 17 1 (2020): 18-26. http://dx.doi.org/10.1089/zeb.2019.1801.
10.1089/zeb.2019.1801
- ML Cancela. "Isolation, Culture, and Differentiation of Blastema Cells from the Regenerating Caudal Fin of Zebrafish". Fishes
(2020): http://dx.doi.org/10.3390/fishes5010006.
10.3390/fishes5010006
- ML Cancela. "Evaluation of MGP gene expression in colorectal cancer". Gene (2020): http://dx.doi.org/10.1016/j.gene.2019.144120.
10.1016/j.gene.2019.144120
- Gil Martins; Laura Ribeiro; Ana Candeias-Mendes; Patrícia Diogo; Margarida Gamboa; Marisa Barata; Maria Leonor Cancela; Pedro
Pousão-Ferreira; Paulo Jorge Gavaia. "Reduction of skeletal anomalies in meagre ( Argyrosomus regius , Asso, 1801) through
early introduction of inert diet". Aquaculture Research 50 10 (2019): 2782-2792. https://doi.org/10.1111/are.14230.
Published • 10.1111/are.14230
- Granadeiro, Luis; Dirks, Ron P.; Ortiz-Delgado, Juan B.; Gavaia, Paulo J.; Sarasquete, Carmen; Laizé, Vincent; Cancela, M.
Leonor; Fernández, Ignacio. "Warfarin-exposed zebrafish embryos resembles human warfarin embryopathy in a dose and developmental-time
dependent manner – From molecular mechanisms to environmental concerns". Ecotoxicology and Environmental Safety 181
(2019): 559-571. http://dx.doi.org/10.1016/j.ecoenv.2019.06.042.
Published • 10.1016/j.ecoenv.2019.06.042
- Santos, João; Mendes-Silva, Leonardo; Afonso, Vanessa; Martins, Gil; Machado, Rui; Lopes, Joao; Cancela, M. Leonor; et al.
"Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants". Cell
Death & Disease 10 8 (2019): 582. http://hdl.handle.net/10400.1/12749.
Open access • Published • 10.1038/s41419-019-1816-6
- ML Cancela. "Intracellular iron uptake is favored in
Hfe
-KO mouse primary chondrocytes mimicking an osteoarthritis-related phenotype". BioFactors (2019): http://dx.doi.org/10.1002/biof.1520.
10.1002/biof.1520
- ML Cancela. "Anti-Osteogenic Activity of Cadmium in Zebrafish". Fishes (2019): http://dx.doi.org/10.3390/fishes4010011.
10.3390/fishes4010011
- Bäck, Magnus; Aranyi, Tamas; Cancela, M. Leonor; Carracedo, Miguel; Conceição, Natércia; Leftheriotis, Georges; Macrae, Vicky;
et al. "Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST
Action EuroSoftCalcNet". Frontiers in Cardiovascular Medicine 5 (2019): 196. http://dx.doi.org/10.3389/fcvm.2018.00196.
Open access • Published • 10.3389/fcvm.2018.00196
- Fernandez, Ignacio; Fernandes, Jorge M. O.; Roberto, Vania P.; Kopp, Martina; Oliveira, Catarina; Riesco, Marta F.; Dias,
Jorge; et al. "Circulating small non-coding RNAs provide new insights into vitamin K nutrition and reproductive physiology
in teleost fish". Biochimica Et Biophysica Acta-General Subjects 1863 1 (2019): 39-51. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000452343100005&KeyUID=WOS:000452343100005.
Open access • Published • 10.1016/j.bbagen.2018.09.017
- Carvalho, Filipe R.; Calado, Sofia M.; Silva, Gabriela A.; Diogo, Gabriela S.; Moreira da Silva, Joana; Reis, Rui L.; Cancela,
M. Leonor; Gavaia, Paulo J.. "Altered bone microarchitecture in a type 1 diabetes mouse model
Ins2
Akita". Journal of Cellular Physiology 234 6 (2018): 9338-9350. http://dx.doi.org/10.1002/jcp.27617.
Published • 10.1002/jcp.27617
- Roberto, Vânia Palma; Gavaia, Paulo; Nunes, Maria João; Rodrigues, Elsa; Cancela, Maria Leonor; Tiago, Daniel Martins. "Evidences
for a New Role of miR-214 in Chondrogenesis". Scientific Reports 8 1 (2018): http://dx.doi.org/10.1038/s41598-018-21735-w.
Open access • Published • 10.1038/s41598-018-21735-w
- Fernández, I.; Gavaia, P.J.; Laizé, V.; Cancela, M.L.. "Fish as a model to assess chemical toxicity in bone". Aquatic Toxicology
194 (2018): 208-226. http://www.scopus.com/inward/record.url?eid=2-s2.0-85035770425&partnerID=MN8TOARS.
Published • 10.1016/j.aquatox.2017.11.015
- Vitorino, Marta; Cunha, Nidia; Conceicao, Natercia; Leonor Cancela, M.. "Expression pattern of cdkl5 during zebrafish early
development: implications for use as model for atypical Rett syndrome". Molecular Biology Reports 45 4 (2018): 445-451.
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000439948500006&KeyUID=WOS:000439948500006.
Published • 10.1007/s11033-018-4180-1
- Fazenda, C.; Martins, G.; Gavaia, P. J.; Cancela, M. L.; Conceicao, N.. "Generation of zebrafish Danio rerio (Hamilton, 1822)
transgenic lines overexpressing a heat-shock mediated Gla-rich protein". Journal of Applied Ichthyology 34 2 (2018):
472-480. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428797200026&KeyUID=WOS:000428797200026.
Published • 10.1111/jai.13662
- Cardeira, J.; Laize, V.; Martins, G.; Cancela, M. L.; Gavaia, P. J.. "An overview on the teleost bone mechanophysiology".
Journal of Applied Ichthyology 34 2 (2018): 440-448. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428797200022&KeyUID=WOS:000428797200022.
Open access • Published • 10.1111/jai.13661
- Carson, Matthew A.; Nelson, John; Cancela, M. Leonor; Laize, Vincent; Gavaia, Paulo J.; Rae, Margaret; Heesch, Svenja; et
al. "Screening for osteogenic activity in extracts from Irish marine organisms: The potential of Ceramium pallidum". Plos
One 13 11 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000451755800060&KeyUID=WOS:000451755800060.
Open access • Published • 10.1371/journal.pone.0207303
- Eckhard Witten, P.; Leonor Cancela, M.. "What aquaculture does for taxonomy, evo-devo, palaeontology, biomechanics and biomedical
research". Journal of Applied Ichthyology 34 2 (2018): 429-430. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428797200020&KeyUID=WOS:000428797200020.
Open access • Published • 10.1111/jai.13670
- Vitorino, M.; Conceicao, N.; Cancela, M. L.; Conceição, N.. "Zebrafish (Danio rerio, Hamilton-Buchanan, 1822) as a model to
study bone diseases associated with Rett syndrome". Journal of Applied Ichthyology 34 2 (2018): 489-500. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428797200028&KeyUID=WOS:000428797200028.
Published • 10.1111/jai.13667
- Silva, Iris A. L.; Conceiceao, Natercia; Gagnon, Edith; Brown, Jacques P.; Cancela, M. Leonor; Michou, Laetitia. "Molecular
effect of an OPTN common variant associated to Paget's disease of bone". Plos One 13 5 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000432537100031&KeyUID=WOS:000432537100031.
Open access • Published • 10.1371/journal.pone.0197543
- Ferreira-Rodriguez, Noe; Fernandez, Ignacio; Leonor Cancela, M.; Pardo, Isabel. "Multibiomarker response shows how native
and non-native freshwater bivalves differentially cope with heat-wave events". Aquatic Conservation-Marine and Freshwater
Ecosystems 28 4 (2018): 934-943. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000442565600016&KeyUID=WOS:000442565600016.
Published • 10.1002/aqc.2884
- Laize, Vincent; Gavaia, Paulo J.; Tarasco, Marco; Viegas, Michael N.; Caria, Joana; Luis, Nuno; Leonor Cancela, M.. "Osteotoxicity
of 3-methylcholanthrene in fish". Ecotoxicology and Environmental Safety 161 (2018): 721-728. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000439956700087&KeyUID=WOS:000439956700087.
Open access • Published • 10.1016/j.ecoenv.2018.06.035
- Carson, Matthew A.; Nelson, John; Cancela, M. Leonor; Laize, Vincent; Gavaia, Paulo J.; Rae, Margaret; Heesch, Svenja; et
al. "Red algal extracts from Plocamium lyngbyanum and Ceramium secundatum stimulate osteogenic activities in vitro and bone
growth in zebrafish larvae". Scientific Reports 8 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000432275800024&KeyUID=WOS:000432275800024.
Open access • Published • 10.1038/s41598-018-26024-0
- Rosa, Joana; Cox, Cymon J.; Leonor Cancela, M.; Laize, Vincent. "Identification of a fish short-chain dehydrogenase/reductase
associated with bone metabolism". Gene 645 (2018): 137-145. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000424182600019&KeyUID=WOS:000424182600019.
Open access • Published • 10.1016/j.gene.2017.12.021
- Roberto, V. P.; Martins, G.; Pereira, A.; Rodrigues, S.; Grenha, A.; Pinto, W.; Cancela, M. L.; Dias, J.; Gavaia, P. J.. "Insights
from dietary supplementation with zinc and strontium on the skeleton of zebrafish, Danio rerio (Hamilton, 1822) larvae: From
morphological analysis to osteogenic markers". Journal of Applied Ichthyology 34 2 (2018): 512-523. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428797200030&KeyUID=WOS:000428797200030.
Open access • Published • 10.1111/jai.13664
- Simao, Marcio; Camacho, Antonio; Cohen-Solal, Martine; Jorge Pinto, I.; Porto, Graca; Korng, Ea Hang; Leonor Cancela, M..
"Iron enriched diet in association with Hfe loss of function promote iron toxicity mechanism and accelerate bone loss phenotype".
Free Radical Biology and Medicine 120 (2018): S148-S148. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000432836500474&KeyUID=WOS:000432836500474.
Open access • Published • 10.1016/j.freeradbiomed.2018.04.489
- Simao, Marcio; Camacho, Antonio; Ostertag, Agnes; Cohen-Solal, Martine; Jorge Pinto, I.; Porto, Graca; Korng, Ea Hang; Leonor
Cancela, M.. "Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis".
Plos One 13 11 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000450138500102&KeyUID=WOS:000450138500102.
Open access • Published • 10.1371/journal.pone.0207441
- Silva, Iris A. L.; Conceição, Natércia; Gagnon, Edith; Caiado, Helena; Brown, Jacques P.; Gianfrancesco, Fernando; Michou,
Laëtitia; et al. "Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone". Biochimica et
Biophysica Acta - Molecular Basis of Disease 1864 1 (2018): 143-151. http://hdl.handle.net/10400.1/10678.
Open access • Published • 10.1016/j.bbadis.2017.10.008
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transgenic lines overexpressing a heat-shock mediated Gla-rich protein". Journal of Applied Ichthyology (2018):
10.1111/JAI.13662
- Saavedra, Carlos; Milan, Massimo; Leite, Ricardo B.; Cordero, David; Patarnello, Tomaso; Cancela, M. Leonor; Bargelloni, Luca.
"A Microarray Study of Carpet-Shell Clam (Ruditapes decussatus) Shows Common and Organ-Specific Growth-Related Gene Expression
Differences in Gills and Digestive Gland". Frontiers in Physiology 8 (2017): 943. http://dx.doi.org/10.3389/fphys.2017.00943.
Open access • Published • 10.3389/fphys.2017.00943
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in a diabetic zebrafish model treated with paricalcitol and cinacalcet". Wound Repair and Regeneration 25 3 (2017):
432-442. http://dx.doi.org/10.1111/wrr.12536.
Open access • Published • 10.1111/wrr.12536
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sensor PXR in a marine flatfish species (Solea senegalensis): Gene expression patterns and its regulation under different
physiological conditions". Marine Environmental Research 130 (2017): 187-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026404560&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.marenvres.2017.07.021
- Surget, G.; Roberto, V.P.; Le Lann, K.; Mira, S.; Guérard, F.; Laizé, V.; Poupart, N.; Cancela, M.L.; Stiger-Pouvreau, V..
"Marine green macroalgae: a source of natural compounds with mineralogenic and antioxidant activities". Journal of Applied
Phycology 29 1 (2017): 575-584. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992135652&partnerID=MN8TOARS.
Published • 10.1007/s10811-016-0968-3
- Ferreira-Rodríguez, N.; Fernández, I.; Varandas, S.; Cortes, R.; Cancela, M.L.; Pardo, I.. "The role of calcium concentration
in the invasive capacity of Corbicula fluminea in crystalline basins". Science of the Total Environment 580 (2017):
1363-1370. http://www.scopus.com/inward/record.url?eid=2-s2.0-85008415001&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.scitotenv.2016.12.100
- Tarasco, M.; Laizé, V.; Cardeira, J.; Cancela, M.L.; Gavaia, P.J.. "The zebrafish operculum: A powerful system to assess osteogenic
bioactivities of molecules with pharmacological and toxicological relevance". Comparative Biochemistry and Physiology Part
- C: Toxicology and Pharmacology 197 (2017): 45-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018759691&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.cbpc.2017.04.006
- Tiago, D.M.; Conceição, N.; Caiado, H.; Laizé, V.; Cancela, M.L.. "Matrix Gla protein repression by MIR-155 promotes oncogenic
signals in breast cancer MCF-7 cells". FEBS Letters 590 8 (2016): 1234-1241. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962855726&partnerID=MN8TOARS.
Open access • Published • 10.1002/1873-3468.12155
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S-methyltransferase 3 in chondral ossification and evidence for sub-functionalization in neoteleost fish". Biochimica et
Biophysica Acta - General Subjects 1860 7 (2016): 1373-1387. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964782089&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.bbagen.2016.03.034
- Marques, C.L.; Fernández, I.; Viegas, M.N.; Cox, C.J.; Martel, P.; Rosa, J.; Cancela, M.L.; Laizé, V.. "Comparative analysis
of zebrafish bone morphogenetic proteins 2, 4 and 16: Molecular and evolutionary perspectives". Cellular and Molecular
Life Sciences 73 4 (2016): 841-857. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957432211&partnerID=MN8TOARS.
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- Roberto, V.P.; Tiago, D.M.; Gautvik, K.; Cancela, M.L.. "Corrigendum to "Evidence for the conservation of miR-223 in zebrafish
(Danio rerio): Implications for function" [Gene 566/1 (2015) 54-62], doi: 10.1016/j.gene.2015.04.022". Gene 576 1 (2016):
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Published • 10.1016/j.gene.2015.10.001
- Correia, E.; Conceição, N.; Cancela, M.L.; Belo, J.A.. "Matrix Gla protein expression pattern in the early avian embryo".
International Journal of Developmental Biology 60 1-3 (2016): 71-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960330410&partnerID=MN8TOARS.
Open access • Published • 10.1387/ijdb.150365jb
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from zebrafish: Evolution, expression and promoter regulation". Archives of Biochemistry and Biophysics 591 (2016):
43-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-84952359771&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.abb.2015.12.004
- Bensimon-Brito, A.; Cardeira, J.; Dionísio, G.; Huysseune, A.; Cancela, M.L.; Witten, P.E.. "Revisiting in vivo staining with
alizarin red S - A valuable approach to analyse zebrafish skeletal mineralization during development and regeneration". BMC
Developmental Biology 16 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84954516804&partnerID=MN8TOARS.
Open access • Published • 10.1186/s12861-016-0102-4
- Medeiros, M.C.R.; Mestre, A.; Inácio, P.; Asgarif, S.; Araújo, I.M.; Hubbard, P.C.; Velez, Z.; et al. "An electrical method
to measure low-frequency collective and synchronized cell activity using extracellular electrodes". Sensing and Bio-Sensing
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Open access • Published • 10.1016/j.sbsr.2016.06.002
- Marques, C.L.; Cancela, M.L.; Laizé, V.. "Transcriptional regulation of gilthead seabream bone morphogenetic protein (BMP)
2 gene by bone- and cartilage-related transcription factors". Gene 576 1 (2016): 229-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979859596&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.gene.2015.10.005
- Cardeira, J.; Gavaia, P.J.; Fernández, I.; Cengiz, I.F.; Moreira-Silva, J.; Oliveira, J.M.; Reis, R.L.; Cancela, M.L.; Laizé,
V.. "Quantitative assessment of the regenerative and mineralogenic performances of the zebrafish caudal fin". Scientific
Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85006713658&partnerID=MN8TOARS.
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- Silva, I. A. L.; Michou, L.; Cancela, M. Leonor; Conceição, Natércia; Cancela, M. L.; Conceicao, N.. "Functional study of
OPTN promoter: new OPTN regulators and effect of genetic variants". European Journal of Clinical Investigation 46 (2016):
124-124. http://hdl.handle.net/10400.1/9534.
Published
- Vitorino, M.; Conceicao, N.; Adrião, Andreia Lúcia Gonçalves; Cancela, M. Leonor; Adriao, A.; Cancela, M. L.. "Zebrafish as
a disease model for studying human Rett Syndrome". P1 (2016): 18. http://hdl.handle.net/10400.1/9535.
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of salinization in a coastal aquifer". (2016): http://hdl.handle.net/10400.1/9760.
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of sperm quality in a type I diabetes zebrafish model". (2016): http://hdl.handle.net/10400.1/9252.
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in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical
stress". Osteoarthritis and Cartilage 24 3 (2016): 494-502. http://hdl.handle.net/10400.1/9606.
Published • https://doi.org/10.1016/j.joca.2015.09.007
- Divisato, Giuseppina; Formicola, Daniela; Esposito, Teresa; Merlotti, Daniela; Pazzaglia, Laura; Del Fattore, Andrea; Siris,
Ethel; et al. "ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor". American Journal of
Human Genetics 98 2 (2016): 275-286. http://hdl.handle.net/10400.1/9627.
https://dx.doi.org/10.1016/j.ajhg.2015.12.016
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on self-reported musculoskeletal complications in hereditary hemochromatosis". PLoS ONE 10 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84926443403&partnerID=MN8TOARS.
Open access • Published • 10.1371/journal.pone.0122817
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and identification of new transcription variants: Implications for function". Archives of Biochemistry and Biophysics
567 (2015): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921028563&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.abb.2014.12.023
- Diogo, P.; Martins, G.; Gavaia, P.; Pinto, W.; Dias, J.; Cancela, L.; Martínez-Páramo, S.. "Assessment of nutritional supplementation
in phospholipids on the reproductive performance of zebrafish, Danio rerio (Hamilton, 1822)". Journal of Applied Ichthyology
31 S1 (2015): 3-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929172664&partnerID=MN8TOARS.
Open access • Published • 10.1111/jai.12733
- Rodrigues, E.T.; Pardal, M.Â.; Laizé, V.; Cancela, M.L.; Oliveira, P.J.; Serafim, T.L.. "Cardiomyocyte H9c2 cells present
a valuable alternative to fish lethal testing for azoxystrobin". Environmental Pollution 206 (2015): 619-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940421879&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.envpol.2015.08.026
- Cardeira, J.; Mendes, A.C.; Pousão-Ferreira, P.; Cancela, M.L.; Gavaia, P.J.. "Micro-anatomical characterization of vertebral
curvatures in Senegalese sole Solea senegalensis". Journal of Fish Biology 86 6 (2015): 1796-1810. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930224873&partnerID=MN8TOARS.
Open access • Published • 10.1111/jfb.12686
- Roberto, V.P.; Tiago, D.M.; Gautvik, K.; Cancela, M.L.. "Evidence for the conservation of miR-223 in zebrafish (Danio rerio):
Implications for function". Gene 566 1 (2015): 54-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929291522&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.gene.2015.04.022
- Fernández, I.; Vijayakumar, P.; Marques, C.; Cancela, M.L.; Gavaia, P.J.; Laizé, V.. "Zebrafish vitamin K epoxide reductases:
expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure". Fish
Physiology and Biochemistry 41 3 (2015): 745-759. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939998188&partnerID=MN8TOARS.
Open access • Published • 10.1007/s10695-015-0043-z
- Fazenda, C.; Conceição, N.; Cancela, M.L.. "Transcription factors from Sox family regulate expression of zebrafish Gla-rich
protein 2 gene". Gene 572 1 (2015): 57-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940609027&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.gene.2015.06.079
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Open access • Published • 10.1111/jai.12506
- Simões, B.; Conceição, N.; Kelsh, R.N.; Cancela, M.L.. "Identification of cis-regulatory elements in the upstream regions
of zebrafish runx3 through in silico analysis: Implications for function". Journal of Applied Ichthyology 30 4 (2014):
661-670. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904873107&partnerID=MN8TOARS.
Open access • Published • 10.1111/jai.12536
- Cancela, M.L.; Laizé, V.; Conceição, N.. "Matrix Gla protein and osteocalcin: From gene duplication to neofunctionalization".
Archives of Biochemistry and Biophysics 561 (2014): 56-63. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907897083&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.abb.2014.07.020
- Tiago, D.M.; Marques, C.L.; Roberto, V.P.; Cancela, M.L.; Laizé, V.. "Mir-20a regulates in vitro mineralization and BMP signaling
pathway by targeting BMP-2 transcript in fish". Archives of Biochemistry and Biophysics 543 (2014): 23-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892628912&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.abb.2013.12.009
- Silva, I.A.L.; Conceição, N.; Michou, L.; Cancela, M.L.. "Can zebrafish be a valid model to study Paget's disease of bone?".
Journal of Applied Ichthyology 30 4 (2014): 678-688. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904917147&partnerID=MN8TOARS.
Open access • Published • 10.1111/jai.12523
- Rosa, J.T.; Cancela, M.L.; Laizé, V.. "Ets1 regulates the transcription of a cartilage-specific S100 protein in gilthead seabream".
Journal of Applied Ichthyology 30 4 (2014): 707-712. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904861722&partnerID=MN8TOARS.
Open access • Published • 10.1111/jai.12534
- Silva, I.A.L.; Cox, C.J.; Leite, R.B.; Cancela, M.L.; Conceição, N.. "Evolutionary conservation of TFIIH subunits: Implications
for the use of zebrafish as a model to study TFIIH function and regulation". Comparative Biochemistry and Physiology Part
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Open access • Published • 10.1016/j.cbpb.2014.03.007
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Archives of biochemistry and biophysics 564 (2014): 173-183. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908322815&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.abb.2014.09.006
- Marques, C.L.; Fernández, I.; Rosa, J.; Viegas, M.N.; Cancela, M.L.; Laizé, V.. "Spatiotemporal expression and retinoic acid
regulation of bone morphogenetic proteins 2, 4 and 16 in Senegalese sole". Journal of Applied Ichthyology 30 4 (2014):
713-720. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904901749&partnerID=MN8TOARS.
Open access • Published • 10.1111/jai.12539
- Fernández, I.; Santos, A.; Cancela, M.L.; Laizé, V.; Gavaia, P.J.. "Warfarin, a potential pollutant in aquatic environment
acting through Pxr signaling pathway and ¿-glutamyl carboxylation of vitamin K-dependent proteins". Environmental Pollution
194 (2014): 86-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905499602&partnerID=MN8TOARS.
Published • 10.1016/j.envpol.2014.07.015
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differentiation and mineralization of two fish bone-derived cell lines: Different gene expression of nuclear receptors and
ECM proteins". Journal of Steroid Biochemistry and Molecular Biology 140 (2014): 34-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890275864&partnerID=MN8TOARS.
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in vitro system to study chondrocyte phenotypes associated to human hereditary hemochromatosis and identify molecular players
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suitable to study bone cell differentiation and extracellular matrix mineralization". Zebrafish 10 4 (2013): 500-509.
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Open access • Published • 10.1089/zeb.2012.0833
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Aquila fasciata". Ibis 155 3 (2013): 485-498. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879607242&partnerID=MN8TOARS.
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development for the Grooved carpet shell clam, Ruditapes decussatus: A functional approach to unravel host -parasite interaction".
BMC Genomics 14 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84886388970&partnerID=MN8TOARS.
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cell culture". Molecular and Cellular Biochemistry 373 1-2 (2013): 41-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871780280&partnerID=MN8TOARS.
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structural features with matrix Gla protein: Evolutionary relationship and functional implications". Journal of Biological
Chemistry 288 39 (2013): 27801-27811. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884788467&partnerID=MN8TOARS.
Open access • Published • 10.1074/jbc.M113.450213
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a model to study craniofacial phenotypes related to human MEF2Cmutations". European Journal of Clinical Investigation
43 (2013): 102-102. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000317141000294&KeyUID=WOS:000317141000294.
Open access • Published
- Silva, I. A. L.; Conceicao, N.; Michou, L.; Cancela, M. L.. "Genetic variation in pdb6 locus and Paget's disease of bone".
European Journal of Clinical Investigation 43 (2013): 81-81. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000317141000235&KeyUID=WOS:000317141000235.
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- Araujo, Nuna C. P.; Afonso, Ricardo; Bringela, A.; Cancela, Leonor; Cristiano, Maria Lurdes Santos; Leite, Ricardo; Araujo,
N.C.P.; et al. "Peroxides with antiplasmodial activity inhibit proliferation of Perkinsus olseni, the causative agent of Perkinsosis
in bivalves". Parasitology International 62 6 (2013): 575-582. http://hdl.handle.net/10400.1/3392.
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regulatory factors for Gla Rich Protein". Journal of Applied Ichthyology 28 3 (2012): 372-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861309532&partnerID=MN8TOARS.
Open access • Published • 10.1111/j.1439-0426.2012.02001.x
- Cardeira, J.; Bensimon-Brito, A.; Pousão-Ferreira, P.; Cancela, M.L.; Gavaia, P.J.. "Lordotic-kyphotic vertebrae develop ectopic
cartilage-like tissue in Senegalese sole (Solea senegalensis)". Journal of Applied Ichthyology 28 3 (2012): 460-463.
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Open access • Published • 10.1111/j.1439-0426.2012.01978.x
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protein (Grp) in zebrafish". Journal of Applied Ichthyology 28 3 (2012): 377-381. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861317124&partnerID=MN8TOARS.
Open access • Published • 10.1111/j.1439-0426.2012.02004.x
- Silva, I.A.L.; Cancela, M.L.; Conceição, N.. "Molecular cloning and expression analysis of XPD from zebrafish (Danio rerio)".
Molecular Biology Reports 39 5 (2012): 5339-5348. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863748620&partnerID=MN8TOARS.
Open access • Published • 10.1007/s11033-011-1333-x
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of the axial and appendicular skeletons of the meagre Argyrosomus regius (Sciaenidae) and early skeletal development at two
rearing facilities". Journal of Applied Ichthyology 28 3 (2012): 464-470. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861308997&partnerID=MN8TOARS.
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- Bensimon-Brito, A.; Cardeira, J.; Cancela, M.L.; Huysseune, A.; Witten, P.E.. "Distinct patterns of notochord mineralization
in zebrafish coincide with the localization of Osteocalcin isoform 1 during early vertebral centra formation". BMC Developmental
Biology 12 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84867115368&partnerID=MN8TOARS.
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on the occurrence of skeletal deformities in Solea senegalensis". Journal of Applied Ichthyology 28 3 (2012): 471-476.
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Published • 10.1111/j.1439-0426.2012.01996.x
- Rafael, M.S.; Laizé, V.; Bensimon-Brito, A.; Leite, R.B.; Schüle, R.; Cancela, M.L.. "Four-and-a-half LIM domains protein
2 (FHL2) is associated with the development of craniofacial musculature in the teleost fish Sparus aurata". Cellular and
Molecular Life Sciences 69 3 (2012): 423-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856224817&partnerID=MN8TOARS.
Open access • Published • 10.1007/s00018-011-0754-y
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"Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone". Bone 51 4 (2012):
720-728. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865636771&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.bone.2012.06.028
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5 (2012): 1128-1134. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859426121&partnerID=MN8TOARS.
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matrix mineralization and gene expression in a gilthead seabream skeletal cell line". Journal of Applied Ichthyology
28 3 (2012): 427-432. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861319375&partnerID=MN8TOARS.
Open access • Published • 10.1111/j.1439-0426.2012.01994.x
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fin endoskeleton in an evo-devo perspective". Evolution and Development 14 1 (2012): 116-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858079912&partnerID=MN8TOARS.
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Febs Journal 279 (2012): 538-539. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000308128602753&KeyUID=WOS:000308128602753.
Open access • Published
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new tool to study mesenchymal cell lineage differentiation in fish". Differentiation 84 3 (2012): 240-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864956867&partnerID=MN8TOARS.
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tissue calcification?". Advances in Nutrition 3 2 (2012): 174-181. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861321582&partnerID=MN8TOARS.
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28 3 (2012): 297-299. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861313151&partnerID=MN8TOARS.
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59 3 (2010): 433-443. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957969737&partnerID=MN8TOARS.
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identification of candidate regulatory factors of cartilage-expressed genes". Journal of Applied Ichthyology 26 2 (2010):
245-250. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954196316&partnerID=MN8TOARS.
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of fish bone-derived cells". Journal of Applied Ichthyology 26 2 (2010): 251-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954211691&partnerID=MN8TOARS.
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vertebral body fusion". Journal of Applied Ichthyology 26 2 (2010): 235-238. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954185246&partnerID=MN8TOARS.
Open access • Published • 10.1111/j.1439-0426.2010.01412.x
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LIM domains protein 2". Febs Journal 277 (2010): 183-183. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000278565100642&KeyUID=WOS:000278565100642.
Open access • Published
- Leite, R. B.; Cancela, M. L.. "Changes at transcriptome level during host-parasite interaction using Perkinsus olseni as a
model". Febs Journal 277 (2010): 118-118. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000278565100422&KeyUID=WOS:000278565100422.
Open access • Published
- Gavaia, Paulo Jorge; Domingues, Susana; Engrola, Sofia; Drake, Pilar; Sarasquete, Carmen; Dinis, M Teresa; Cancela, M Leonor;
et al. "Comparing skeletal development of wild and hatchery-reared Senegalese sole (Solea senegalensis, Kaup 1858): evaluation
in larval and postlarval stages". Aquaculture Research 40 14 (2009): 1585-1593. http://dx.doi.org/10.1111/j.1365-2109.2009.02258.x.
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with different susceptibility to perkinsosis". Journal of Fish Diseases 32 7 (2009): 633-636. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650803089&partnerID=MN8TOARS.
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"Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications".
American Journal of Pathology 175 6 (2009): 2288-2298. http://www.scopus.com/inward/record.url?eid=2-s2.0-73549121071&partnerID=MN8TOARS.
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gla protein in turbot (Scophthalmus maximus): gene expression analysis and identification of sites of protein accumulation".
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and osteocalcin from the adriatic sturgeon (Acipencer naccarii), an Ancient bony fish with a cartilaginous endoskeleton".
Bone 42 (2008): S65-S65. http://dx.doi.org/10.1016/j.bone.2007.12.116.
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of Environmental Contamination and Toxicology 80 6 (2008): 512-515. http://www.scopus.com/inward/record.url?eid=2-s2.0-46249130791&partnerID=MN8TOARS.
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protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates".
Journal of Biological Chemistry 283 52 (2008): 36655-36664. http://www.scopus.com/inward/record.url?eid=2-s2.0-61349170719&partnerID=MN8TOARS.
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2 (2008): 107-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-44849127081&partnerID=MN8TOARS.
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- Tanguy, A.; Bierne, N.; Saavedra, C.; Pina, B.; Bachère, E.; Kube, M.; Bazin, E.; et al. "Increasing genomic information in
bivalves through new EST collections in four species: Development of new genetic markers for environmental studies and genome
evolution". Gene 408 1-2 (2008): 27-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-37549048659&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.gene.2007.10.021
- Coesel, S.N.; Baumgartner, A.C.; Teles, L.M.; Ramos, A.A.; Henriques, N.M.; Cancela, L.; Varela, J.C.S.. "Nutrient limitation
is the main regulatory factor for carotenoid accumulation and for Psy and Pds steady state transcript levels in Dunaliella
salina (Chlorophyta) exposed to high light and salt stress". Marine Biotechnology 10 5 (2008): 602-611. http://www.scopus.com/inward/record.url?eid=2-s2.0-49349108166&partnerID=MN8TOARS.
Open access • 10.1007/s10126-008-9100-2
- Conceição, N.; Laizé, V.; Simões, B.; Pombinho, A.R.; Cancela, M.L.. "Retinoic acid is a negative regulator of matrix Gla
protein gene expression in teleost fish Sparus aurata". Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
1779 1 (2008): 28-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-39449109869&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.bbagrm.2007.11.003
- Tiago, D.M.; Cancela, M.L.; Aureliano, M.; Laizé, V.. "Vanadate proliferative and anti-mineralogenic effects are mediated
by MAPK and PI-3K/Ras/Erk pathways in a fish chondrocyte cell line". FEBS Letters 582 9 (2008): 1381-1385. http://www.scopus.com/inward/record.url?eid=2-s2.0-41449118290&partnerID=MN8TOARS.
Open access • Published • 10.1016/j.febslet.2008.03.025
- Tiago, Daniel; Cancela, Leonor; Aureliano, M.; Laizé, Vincent. "Vanadate proliferative and anti-mineralogic effects are mediated
by MAPK and PI-3K/Ras/Erk pathways in a fish chondrocyte cell line". (2008): http://hdl.handle.net/10400.1/1359.
- Tiago, Daniel; Laizé, Vincent; Cancela, Leonor; Aureliano, M.. "Impairment of mineralization by metavanadate and decavanadate
solutions in a fish bone-derived cell line". (2008): http://hdl.handle.net/10400.1/4707.
http://dx.doi.org/10.1007/s10565-007-9034-x
- Tiago, Daniel; Laizé, Vincent; Cancela, Leonor; Aureliano, M.. "Impairment of mineralization by metavanadate and decavanadate
solutions in a fish bone-derived cell line". (2008): http://hdl.handle.net/10400.1/1361.
- Fonseca, P. J.; Serrão, Ester; Pina-Martins, F.; Silva, P.; Mira, Sara; Quartau, J. A.; Paulo, O. S.; et al. "The evolution
of Cicada songs contrasted with the relationships inferred from mitochondrial DNA (Insecta, hemiptera)". Bioacoustics
18 1 (2008): 17-34. http://hdl.handle.net/10400.1/4213.
Published • http://dx.doi.org/ 10.1080/09524622.2008.9753588
- Kohli, V.; Robles, V.; Cancela, M.L.; Acker, J.P.; Waskiewicz, A.J.; Elezzabi, A.Y.. "An alternative method for delivering
exogenous material into developing zebrafish embryos". Biotechnology and Bioengineering 98 6 (2007): 1230-1241. http://www.scopus.com/inward/record.url?eid=2-s2.0-36749097906&partnerID=MN8TOARS.
10.1002/bit.21564
- Fonseca, V.G.; Laizé, V.; Valente, M.S.; Cancela, M.L.. "Identification of an osteopontin-like protein in fish associated
with mineral formation". FEBS Journal 274 17 (2007): 4428-4439. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548141795&partnerID=MN8TOARS.
Open access • Published • 10.1111/j.1742-4658.2007.05972.x
- Robles, V.; Cancela, M.L.. "Lipid-based transfection as a method for gene delivery in zebrafish (Danio rerio) embryos". Aquaculture
Research 38 12 (2007): 1317-1322. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548357269&partnerID=MN8TOARS.
Published • 10.1111/j.1365-2109.2007.01806.x
- Rønnestad, I.; Gavaia, P.J.; Viegas, C.S.B.; Verri, T.; Romano, A.; Nilsen, T.O.; Jordal, A.-E.O.; Kamisaka, Y.; Cancela,
M.L.. "Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L.): Cloning, tissue expression and comparative aspects".
Journal of Experimental Biology 210 22 (2007): 3883-3896. http://www.scopus.com/inward/record.url?eid=2-s2.0-37249063715&partnerID=MN8TOARS.
Published • 10.1242/jeb.007898
- Robles, V.; Barbosa, V.; Herráez, M.P.; Martínez-Páramo, S.; Cancela, M.L.. "The antifreeze protein type I (AFP I) increases
seabream (Sparus aurata) embryos tolerance to low temperatures". Theriogenology 68 2 (2007): 284-289. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250178781&partnerID=MN8TOARS.
Published • 10.1016/j.theriogenology.2007.05.003
- Marques, C. L.; Rafael, M. S.; Cancela, Leonor; Laizé, Vincent; Marques, C.L.; Rafael, M.S.; Cancela, M.L.; Laizé, V.. "Establishment
of primary cell cultures from fish calcified tissues". Cytotechnology 55 1 (2007): 9-13. http://hdl.handle.net/10400.1/4334.
http://dx.doi.org/10.1007/s10616-007-9098-8
- Ortiz-Delgado, J.B.; Simes, D.C.; Viegas, C.S.B.; Schaff, B.J.; Sarasquete, C.; Cancela, M.L.. "Cloning of matrix Gla protein
in a marine cartilaginous fish, Prionace glauca: Preferential protein accumulation in skeletal and vascular systems". Histochemistry
and Cell Biology 126 1 (2006): 89-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745063198&partnerID=MN8TOARS.
Published • 10.1007/s00418-005-0125-6
- Gavaia, P.J.; Simes, D.C.; Ortiz-Delgado, J.B.; Viegas, C.S.B.; Pinto, J.P.; Kelsh, R.N.; Sarasquete, M.C.; Cancela, M.L..
"Osteocalcin and matrix Gla protein in zebrafish (Danio rerio) and Senegal sole (Solea senegalensis): Comparative gene and
protein expression during larval development through adulthood". Gene Expression Patterns 6 6 (2006): 637-652. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646862665&partnerID=MN8TOARS.
Published • 10.1016/j.modgep.2005.11.010
- Braga, D.; Laizé, V.; Tiago, D.M.; Cancela, M.L.. "Enhanced DNA transfer into fish bone cells using polyethylenimine". Molecular
Biotechnology 34 1 (2006): 51-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748370298&partnerID=MN8TOARS.
Published • 10.1385/MB:34:1:51
- Simões, B.; Conceição, N.; Viegas, C.S.B.; Pinto, J.P.; Gavaia, P.J.; Hurst, L.D.; Kelsh, R.N.; Cancela, M.L.. "Identification
of a promoter element within the Zebrafish colXa1 gene responsive to Runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2aA2".
Calcified Tissue International 79 4 (2006): 230-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750561072&partnerID=MN8TOARS.
Published • 10.1007/s00223-006-0111-6
- Laizé, V.; Viegas, C.S.B.; Price, P.A.; Cancela, M.L.. "Identification of an osteocalcin isoform in fish with a large acidic
prodomain". Journal of Biological Chemistry 281 22 (2006): 15037-15043. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744965092&partnerID=MN8TOARS.
Open access • Published • 10.1074/jbc.M600373200
- Rafael, M.S.; Laizé, V.; Cancela, M.L.. "Identification of Sparus aurata bone morphogenetic protein 2: Molecular cloning,
gene expression and in silico analysis of protein conserved features in vertebrates". Bone 39 6 (2006): 1373-1381.
http://www.scopus.com/inward/record.url?eid=2-s2.0-35448991288&partnerID=MN8TOARS.
Published • 10.1016/j.bone.2006.06.021
- Rønnestad, I.; Gavaia, Paulo J.; Viegas, C. S. B.; Verri, T.; Cancela, Leonor. "PepT1 in a coldwater marine teleost larvae-
Atlantic cod: cloning and preliminary studies of expression and phylogeny". Acta Bio Medica. 77 (2006): 82. http://hdl.handle.net/10400.1/4498.
Published
- Engrola, S.; Conceição, L.E.C.; Gavaia, P.J.; Cancela, M.L.; Dinis, M.T.. "Effects of pre-weaning feeding frequency on growth,
survival, and deformation of Senegalese sole, Solea senegalensis (Kaup, 1858)". Israeli Journal of Aquaculture - Bamidgeh
57 1 (2005): 10-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-16344396118&partnerID=MN8TOARS.
- Laizé, V.; Pombinho, A.R.; Cancela, M.L.; Laizé, Vincent; Pombinho, A. R.; Cancela, Leonor. "Characterization of Sparus aurata
osteonectin cDNA and in silico analysis of protein conserved features: Evidence for more than one osteonectin in Salmonidae".
Biochimie 87 5 (2005): 411-420. http://www.scopus.com/inward/record.url?eid=2-s2.0-16844379888&partnerID=MN8TOARS.
10.1016/j.biochi.2005.01.008
- Elandalloussi, L.M.; Leite, R.B.; Rodrigues, P.M.; Afonso, R.; Nunes, P.A.; Cancela, M.L.. "Effect of antiprotozoal drugs
on the proliferation of the bivalve parasite Perkinsus olseni". Aquaculture 243 1-4 (2005): 9-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-10644265408&partnerID=MN8TOARS.
10.1016/j.aquaculture.2004.09.038
- Fonseca, V.G.; Lago-Lestón, A.; Laizé, V.; Cancela, M.L.; Fonseca, V. G.; Laizé, Vincent; Cancela, Leonor. "Rapid identification
of differentially expressed genes by in situ screening of bacteria". Molecular Biotechnology 30 2 (2005): 163-165.
http://www.scopus.com/inward/record.url?eid=2-s2.0-22344433118&partnerID=MN8TOARS.
10.1385/MB:30:2:163
- Elandalloussi, L.M.; Rodrigues, P.M.; Afonso, R.; Leite, R.B.; Nunes, P.A.; Cancela, M.L.. "Shikimate and folate pathways
in the protozoan parasite, Perkinsus olseni". Molecular and Biochemical Parasitology 142 1 (2005): 106-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-19344373699&partnerID=MN8TOARS.
10.1016/j.molbiopara.2005.03.014
- Frazão, C.; Simes, D.C.; Coelho, R.; Alves, D.; Williamson, M.K.; Price, P.A.; Cancela, M.L.; Carrondo, M.A.. "Structural
evidence of a fourth Gla residue in fish osteocalcin: Biological implications". Biochemistry 44 4 (2005): 1234-1242.
http://www.scopus.com/inward/record.url?eid=2-s2.0-13444271638&partnerID=MN8TOARS.
10.1021/bi048336z
- Conceição, N.; Silva, A.C.; Fidalgo, J.; Belo, J.A.; Cancela, M.L.. "Identification of alternative promoter usage for the
matrix Gla protein gene: Evidence for differential expression during early development in Xenopus laevis". FEBS Journal
272 6 (2005): 1501-1510. http://www.scopus.com/inward/record.url?eid=2-s2.0-15944374190&partnerID=MN8TOARS.
10.1111/j.1742-4658.2005.04590.x
- Mira, S.; Wolff, K.; Cancela, M.L.. "Isolation and characterization of microsatellite markers in Bonelli's eagle (Hieraaetus
fasciatus)". Molecular Ecology Notes 5 3 (2005): 493-495. http://www.scopus.com/inward/record.url?eid=2-s2.0-28344450284&partnerID=MN8TOARS.
10.1111/j.1471-8286.2005.00967.x
- Ortiz-Delgado, J. B.; Simes, Dina; Gavaia, Paulo J.; Sarasquete, C.; Cancela, Leonor; Ortiz-Delgado, J.B.; Simes, D.C.; Gavaia,
P.; Cancela, M.L.. "Osteocalcin and Matrix Gla Protein in developing teleost teeth. Identification of sites of mRNA and protein
accumulation at single cell resolution". Histochemistry and Cell Biology 124 2 (2005): 123-130. http://hdl.handle.net/10400.1/4508.
http://dx.doi.org/10.1007/s00418-005-0015-y
- Laizé, Vincent; Martel, Paulo; Viegas, Carla; Price, P. A.; Cancela, Leonor; Laizé, V.; Martel, P.; et al. "Evolution of matrix
and bone gamma-carboxyglutamic acid proteins in vertebrates". Journal of Biological Chemistry 280 29 (2005): 26659-26668.
http://hdl.handle.net/10400.1/4282.
http://dx.doi.org/ 10.1074/jbc.M500257200
- Engrola, S.; Conceição, L. E. C.; Gavaia, Paulo J.; Cancela, Leonor; Dinis, Maria Teresa. "Effect of pre-weaning feeding regime
on weaning performance of Senegalese sole, Solea senegalensis (Kaup, 1858)". Despite much interest in the production of
Senegalese sole (Solea senegalensis) in southern Europe, weaning of this species onto artificial diets is problematic and
varying results are obtained. The aim of this study was to test two feeding frequencies during a 13-day pre-weaning period
and assess their impact on the growth and survival of Senegalese sole. Postlarvae were fed Artemia metanauplii w (2005):
http://hdl.handle.net/10400.1/4483.
- Elandalloussi, L. M.; Rodrigues, Pedro; Afonso, R.; Leite, R. B.; Nunes, Patrícia A.; Cancela, Leonor. "Shikimate and folate
pathways in the protozoan parasite, Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/7217.
https://dx.doi.org/10.1016/j.molbiopara.2005.03.014
- Elandalloussi, Laurence M.; Leite, Ricardo B.; Rodrigues, Pedro; Afonso, Ricardo; Nunes, Patrícia A.; Cancela, Leonor. "Effect
of antiprotozoal drugs on the proliferation of the bivalve parasite Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/4402.
http://dx.doi.org/10.1016/j.aquaculture.2004.09.038
- Elandalloussi, Laurence M.; Rodrigues, Pedro; Afonso, Ricardo; Leite, Ricardo B.; Nunes, Patrícia A.; Cancela, Leonor. "Shikimate
and folate pathways in the protozoan parasite, Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/4362.
http://dx.doi.org/10.1016/j.molbiopara.2005.03.014
- Elandalloussi, L. M.; Leite, R. B.; Rodrigues, Pedro; Afonso, R.; Nunes, Patrícia A.; Cancela, Leonor. "Effect of antiprotozoal
drugs on the proliferation of the bivalve parasite Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/7218.
https://dx.doi.org/10.1016/j.aquaculture.2004.09.038
- Elandalloussi, L. M.; Rodrigues, Pedro; Afonso, R.; Leite, R. B.; Nunes, Patrícia A.; Cancela, Leonor. "Shikimate and folate
pathways in the protozoan parasite, Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/7217.
https://dx.doi.org/10.1016/j.molbiopara.2005.03.014
- Pinto, Jorge; Conceição, Natércia; S B Viegas, Carla; Leite, Ricardo; Hurst, L. D.; Kelsh, R. N.; Leonor Cancela, M.; et al.
"Identification of a new pebp2 alpha A2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro".
Journal of Bone and Mineral Research 20 8 (2005): 1440-1453. http://hdl.handle.net/10400.1/11176.
10.1359/JBMR.050318
- Elandalloussi, Laurence M.; Leite, Ricardo B.; Rodrigues, Pedro; Afonso, Ricardo; Nunes, Patrícia A.; Cancela, Leonor. "Effect
of antiprotozoal drugs on the proliferation of the bivalve parasite Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/4402.
http://dx.doi.org/10.1016/j.aquaculture.2004.09.038
- Elworthy, S.; P Pinto, Jorge; Pettifer, A.; Leonor Cancela, M.; Kelsh, R. N.; Pinto, J.P.; Cancela, M.L.; Kelsh, R.N.. "Phox2b
function in the enteric nervous system is conserved in zebrafish and is sox10-dependent". Mechanisms of Development
122 5 (2005): 659-669. http://hdl.handle.net/10400.1/11721.
10.1016/j.mod.2004.12.008
- Elandalloussi, L. M.; Leite, R. B.; Rodrigues, Pedro; Afonso, R.; Nunes, Patrícia A.; Cancela, Leonor. "Effect of antiprotozoal
drugs on the proliferation of the bivalve parasite Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/7218.
https://dx.doi.org/10.1016/j.aquaculture.2004.09.038
- Elandalloussi, Laurence M.; Rodrigues, Pedro; Afonso, Ricardo; Leite, Ricardo B.; Nunes, Patrícia A.; Cancela, Leonor. "Shikimate
and folate pathways in the protozoan parasite, Perkinsus olseni". (2005): http://hdl.handle.net/10400.1/4362.
http://dx.doi.org/10.1016/j.molbiopara.2005.03.014
- Simes, D.C.; Williamson, M.K.; Schaff, B.J.; Gavaia, P.J.; Ingleton, P.M.; Price, P.A.; Cancela, M.L.; et al. "Characterization
of Osteocalcin (BGP) and Matrix Gla Protein (MGP) Fish Specific Antibodies: Validation for Immunodetection Studies in Lower
Vertebrates". Calcified Tissue International 74 2 (2004): 170-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342302340&partnerID=MN8TOARS.
10.1007/s00223-003-0079-4
- Elandalloussi, L.M.; Leite, R.M.; Afonso, R.; Nunes, P.A.; Robledo, J.A.F.; Vasta, G.R.; Cancela, M.L.. "Development of a
PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs". Molecular
and Cellular Probes 18 2 (2004): 89-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642502971&partnerID=MN8TOARS.
10.1016/j.mcp.2003.09.008
- Streiff, R.; Mira, S.; Castro, M.; Cancela, M.L.. "Multiple paternity in Norway lobster (Nephrops norvegicus L.) assessed
with microsatellite markers". Marine Biotechnology 6 1 (2004): 60-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642264028&partnerID=MN8TOARS.
10.1007/s10126-003-0015-7
- Leite, R.B.; Afonso, R.; Cancela, M.L.. "Perkinsus sp. infestation in carpet-shell clams, Ruditapes decussatus (L), along
the Portuguese coast. Results from a 2-year survey". Aquaculture 240 1-4 (2004): 39-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-4744368358&partnerID=MN8TOARS.
10.1016/j.aquaculture.2004.05.014
- Elandalloussi, L. M.; Leite, R. M.; Afonso, R.; Nunes, Patrícia A.; Robledo, J. A. F.; Vasta, G. R.; Cancela, Leonor. "Development
of a PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs". (2004):
http://hdl.handle.net/10400.1/7219.
https://dx.doi.org/10.1016/j.mcp.2003.09.008
- Elandalloussi, L. M.; Leite, R. M.; Afonso, R.; Nunes, Patrícia A.; Robledo, J. A. F.; Vasta, G. R.; Cancela, Leonor. "Development
of a PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs". (2004):
http://hdl.handle.net/10400.1/7219.
https://dx.doi.org/10.1016/j.mcp.2003.09.008
- Pombinho, A. R.; Laizé, Vincent; Molha, D. M.; Marques, S.; Cancela, Leonor; Pombinho, A.R.; Laizé, V.; et al. "Development
of two bone-derived cell lines from the marine teleost Sparus aurata; evidence for extracellular matrix mineralization and
cell-type-specific expression of matrix Gla protein and osteocalcin". Cell and Tissue Research 315 3 (2004): 393-406.
http://hdl.handle.net/10400.1/4299.
http://doi:10.1152/ 10.1007/s00441-003-0830-1
- Aurelle, D.; Guillemaud, T.; Afonso, P.; Morato, T.; Wirtz, P.; Serrão Santos, R.; Cancela, M.L.. "Genetic study of Coris
julis (Osteichtyes, Perciformes, Labridae) evolutionary history and dispersal abilities". Comptes Rendus - Biologies
326 8 (2003): 771-785. http://www.scopus.com/inward/record.url?eid=2-s2.0-0142149228&partnerID=MN8TOARS.
10.1016/j.crvi.2003.08.001
- Pinto, J.P.; Conceição, N.; Gavaia, P.J.; Cancela, M.L.. "Matrix Gla protein gene expression and protein accumulation colocalize
with cartilage distribution during development of the teleost fish Sparus aurata". Bone 32 3 (2003): 201-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037347260&partnerID=MN8TOARS.
10.1016/S8756-3282(02)00981-X
- Simes, D.C.; Williamson, M.K.; Ortiz-Delgado, J.B.; Viegas, C.S.B.; Price, P.A.; Cancela, M.L.; Simes, DC; et al. "Purification
of matrix Gla protein from a marine teleost fish, Argyrosomus regius: Calcified cartilage and not bone as the primary site
of MGP accumulation in fish". Journal of Bone and Mineral Research 18 2 (2003): 244-259. http://www.scopus.com/inward/record.url?eid=2-s2.0-12244249480&partnerID=MN8TOARS.
10.1359/jbmr.2003.18.2.244
- Elandalloussi, L. M.; Afonso, R.; Nunes, Patrícia A.; Cancela, Leonor; Elandalloussi, L.M.; Nunes, P.A.; Cancela, M.L.. "Effect
of desferrioxamine and 2,2 '-bipyridyl on the proliferation of Perkinsus atlanticus". Biomolecular Engineering 20 4-6
(2003): 349-354. http://hdl.handle.net/10400.1/7220.
https://dx.doi.org/10.1016/S1389-0344(03)00047-9
- Pinto, J. P.; Conceição, N.; Gavaia, Paulo J.; Cancela, Leonor. "Matrix Gla protein gene expression and protein accumulation
co-localize with cartilage distribution during development of the teleost fish Sparus aurata". (2003): http://hdl.handle.net/10400.1/4383.
http://dx.doi.org/10.1016/S8756-3282(02)00981-X
- Pinto, J. P.; Conceição, N.; Gavaia, Paulo J.; Cancela, Leonor. "Matrix Gla protein gene expression and protein accumulation
co-localize with cartilage distribution during development of the teleost fish Sparus aurata". (2003): http://hdl.handle.net/10400.1/4493.
http://dx.doi.org/10.1016/S8756-3282(02)00981-X
- Leite, Ricardo B.; Rodrigues, Pedro; Elandalloussi, Laurence M.; Afonso, Ricardo; Nunes, Patrícia A.; Cancela, Leonor. "Perkinsus
Atlanticus – desenvolvimento de um método de diagnóstico para detecção de infecção em moluscos bivalves". (2003): http://hdl.handle.net/10400.1/4335.
- Robledo, J.A.F.; Nunes, P.A.; Cancela, M.L.; Vasta, G.R.. "Development of an in vitro clonal culture and characterization
of the rRNA gene cluster of Perkinsus atlanticus, a protistan parasite of the clam Tapes decussatus". Journal of Eukaryotic
Microbiology 49 5 (2002): 414-422. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036710887&partnerID=MN8TOARS.
- Viegas, C.S.B.; Pinto, J.P.; Conceição, N.; Simes, D.C.; Cancela, M.L.. "Cloning and characterization of the cDNA and gene
encoding Xenopus laevis osteocalcin". Gene 289 1-2 (2002): 97-107. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036572833&partnerID=MN8TOARS.
10.1016/S0378-1119(02)00480-8
- Mira, S.; Billot, C.; Guillemaud, T.; Palma, L.; Cancela, M.L.. "Isolation and characterization of polymorphic microsatellite
markers in Eurasian vulture Gyps fulvus". Molecular Ecology Notes 2 4 (2002): 557-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036899159&partnerID=MN8TOARS.
10.1046/j.1471-8286.2002.00314.x
- Conceição, N.; Henriques, N.M.; Ohresser, M.C.P.; Hublitz, P.; Schüle, R.; Cancela, M.L.. "Molecular cloning of the Matrix
Gla Protein gene from Xenopus laevis: Functional analysis of the promoter identifies a calcium sensitive region required for
basal activity". European Journal of Biochemistry 269 7 (2002): 1947-1956. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036231825&partnerID=MN8TOARS.
10.1046/j.1432-1327.2002.02846.x
- Gavaia, Paulo J.; Dinis, Maria Teresa; Cancela, Leonor; Gavaia, P.J.; Dinis, M.T.; Cancela, M.L.. "Osteological development
and abnormalities of the vertebral column and caudal skeleton in larval and juvenile stages of hatchery-reared Senegal sole
(Solea senegalensis)". Aquaculture 211 1-4 (2002): 305-323. http://hdl.handle.net/10400.1/4497.
http://dx.doi.org/10.1016/S0044-8486(02)00167-9
- Robledo, J. A. F.; Nunes, Patrícia A.; Cancela, Leonor; Vasta, G. R.. "Development of an in vitro clonal culture and characterization
of the rRNA gene cluster of Perkinsus atlanticus, a protistan parasite of the clam Tapes decussatus". (2002): http://hdl.handle.net/10400.1/7221.
https://dx.doi.org/10.1111/j.1550-7408.2002.tb00221.x
- Henriques, M.; Lourenco, R.; Almada, F.; Calado, G.; Goncalves, D.; Guillemaud, Thomas; Cancela, M. Leonor; et al. "A revision
of the status of Lepadogaster lepadogaster (Teleostei : Gobiesocidae): sympatric subspecies or a long misunderstood blend
of species?". Biological Journal of the Linnean Society 76 3 (2002): 327-338. http://hdl.handle.net/10400.1/11484.
10.1111/j.1095-8312.2002.tb01700.x
- Streiff, R.; Guillemaud, T.; Alberto, F.; Magalhães, J.; Castro, M.; Cancela, M.L.. "Isolation and characterization of microsatellite
loci in the Norway lobster (Nephrops norvegicus)". Molecular Ecology Notes 1 1-2 (2001): 71-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346342219&partnerID=MN8TOARS.
Published
- Cancela, M.L.; Ohresser, M.C.P.; Reia, J.P.; Viegas, C.S.B.; Williamson, M.K.; Price, P.A.. "Matrix Gla protein in Xenopus
laevis: Molecular cloning, tissue distribution, and evolutionary considerations". Journal of Bone and Mineral Research
16 9 (2001): 1611-1621. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034868048&partnerID=MN8TOARS.
Published
- Palma, L.; Mira, S.; Cardia, P.; Beja, P.; Guillemaud, T.; Ferrand, N.; Cancela, M.L.; Da Fonseca, L.C.. "Sexing bonelli's
eagle nestlings: Morphometrics versus molecular techniques". Journal of Raptor Research 35 3 (2001): 187-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-16344361957&partnerID=MN8TOARS.
Published
- Pinto, J.P.; Ohresser, M.C.P.; Cancela, M.L.. "Cloning of the bone Gla protein gene from the teleost fish Sparus aurata. Evidence
for overall conservation in gene organization and bone-specific expression from fish to man". Gene 270 1-2 (2001):
77-91. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035972741&partnerID=MN8TOARS.
10.1016/S0378-1119(01)00426-7
- Simes, Dina; Gavaia, Paulo J.; Ortiz-Delgado, J. B.; Pinto, J. P.; Cancela, Leonor. "Characterization of specific antibodies
for fish osteocalcin and its usefulness to investigate osteocalcin tissue distribution in lower vertebrates.". Calcified
Tisue International 74 (2001): 170-180. http://hdl.handle.net/10400.1/4426.
Published
- Gavaia, Paulo J.; Viegas, C. A.; Pinto, J. P.; Sarasquete, C.; Cancela, Leonor. "Detection and localization of osteocalcin
(BGP or Bone Gla Protein) in teleosts by in situ hybridization and immunohistochemistry". Bone 28 5 (2001): S103. http://hdl.handle.net/10400.1/4468.
Published
- Pearson, G. A.; Serrão, Ester; Cancela, Leonor; Pearson, G.; Serrão, E.A.; Cancela, M.L.. "Suppression subtractive hybridization
for studying gene expression during aerial exposure and desiccation in fucoid algae". European Journal of Phycology
36 4 (2001): 359-366. http://hdl.handle.net/10400.1/4061.
Published • http://dx.doi.org/ 10.1080/09670260110001735508
- Cancela, M. Leonor; Ohresser, M. C. P.; Reia, J. P.; S B Viegas, Carla; Williamson, M. K.; Price, P. A.. "Matrix gla protein
in xenopus laevis: molecular cloning, tissue distribution, and evolutionary considerations". (2001): http://hdl.handle.net/10400.1/11930.
10.1359/jbmr.2001.16.9.1611
- Gavaia, P.J.; Sarasquete, C.; Cancela, M.L.. "Detection of mineralized structures in early stages of development of marine
Teleostei using a modified alcian blue-alizarin red double staining technique for bone and cartilage". Biotechnic and Histochemistry
75 2 (2000): 79-84. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033860776&partnerID=MN8TOARS.
Published
- Guillemaud, T.; Cancela, M.L.; Afonso, P.; Morato, T.; Santos, R.S.; Wirtz, P.. "Molecular insights into the taxonomic status
of Coris atlantica (Pisces: Labridae)". Journal of the Marine Biological Association of the United Kingdom 80 5 (2000):
929-933. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033671065&partnerID=MN8TOARS.
Published • 10.1017/S0025315400002915
- Guillemaud, T.; Almada, F.; Santos, R.S.; Cancela, M.L.. "Interspecific utility of microsatellites in fish: A case study of
(CT)(n) and (GT)(n) markers in the shanny Lipophrys pholis (Pisces: Blenniidae) and their use in other blennioidei". Marine
Biotechnology 2 3 (2000): 248-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034190159&partnerID=MN8TOARS.
Published
- Carvalho, M.C.; Streiff, R.; Guillemaud, T.; Afonso, P.; Santos, R.S.; Cancela, M.L.. "Isolation and characterization of polymorphic
microsatellite markers in Abudefduf luridus (Pisces: Pomacentridae)". Molecular Ecology 9 7 (2000): 993-994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033911313&partnerID=MN8TOARS.
Published • 10.1046/j.1365-294X.2000.00939.x
- Guillemaud, T.; Streiff, R.; Santos, R.S.; Afonso, P.; Morato, T.; Cancela, M.L.. "Microsatellite characterization in the
rainbow wrasse Coris julis (Pisces: Labridae)". Molecular Ecology 9 5 (2000): 631-632. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034060782&partnerID=MN8TOARS.
10.1046/j.1365-294X.2000.00882-1.x
- Cancela, M.L.; Hu, B.; Price, P.A.. "Effect of cell density and growth factors on matrix GLA protein expression by normal
rat kidney cells". Journal of Cellular Physiology 171 2 (1997): 125-134. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030974786&partnerID=MN8TOARS.
Published • 10.1002/(SICI)1097-4652(199705)171:2<125::AID-JCP2>3.0.CO;2-Q
- Kirfel, J.; Kelter, M.; Cancela, L.M.; Price, P.A.; Schüle, R.. "Identification of a novel negative retinoic acid responsive
element in the promoter of the human matrix Gla protein gene". Proceedings of the National Academy of Sciences of the United
States of America 94 6 (1997): 2227-2232. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030992162&partnerID=MN8TOARS.
Published • 10.1073/pnas.94.6.2227
- Cancela, M.L.; Williamson, M.K.; Price, P.A.. "Amino-acid sequence of bone Gla protein from the African clawed toad Xenopus
laevis and the fish Sparus aurata". International Journal of Peptide and Protein Research 46 5 (1995): 419-423. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028864789&partnerID=MN8TOARS.
Published
- Cancela, M.L.; Williamson, M.K.; Price, P.A.. "The putative RGD-dependent cell adhesion activity of matrix Gla protein is
due to higher molecular weight contaminants". Journal of Biological Chemistry 269 16 (1994): 12185-12189. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028233411&partnerID=MN8TOARS.
Open access • Published
- Rannels, S.R.; Cancela, M.L.; Wolpert, E.B.; Price, P.A.. "Matrix Gla protein mRNA expression in cultured type II pneumocytes".
American Journal of Physiology - Lung Cellular and Molecular Physiology 265 3 9-3 (1993): http://www.scopus.com/inward/record.url?eid=2-s2.0-0027453375&partnerID=MN8TOARS.
Published
- Cancela, M.L.; Williamson, M.K.; Price, P.A.. "Retinoic acid increases matrix gla protein in rat plasma". Nutrition Research
13 1 (1993): 87-91. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027535868&partnerID=MN8TOARS.
Published • 10.1016/S0271-5317(05)80659-1
- Cancela, M.L.; Price, P.A.. "Retinoic acid induces matrix gla protein gene expression in human cells". Endocrinology
130 1 (1992): 102-108. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026553049&partnerID=MN8TOARS.
Published
- Cancela, L.; Ishida, H.; Bishop, J.E.; Norman, A.W.. "Local chromatin changes accompany the expression of the calbindin-D28K
gene: Tissue specificity and effect of vitamin D activation". Molecular Endocrinology 6 3 (1992): 468-475. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026525323&partnerID=MN8TOARS.
Published
- Cancela, L.; Hsieh, C.-L.; Francke, U.; Price, P.A.. "Molecular structure, chromosome assignment, and promoter organization
of the human matrix Gla protein gene". Journal of Biological Chemistry 265 25 (1990): 15040-15048. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025029949&partnerID=MN8TOARS.
Open access • Published
- PARISI, M; CANCELA, L; Parisi, M.; Cancela, L.. "TIME COURSE STUDIES ON PHOSPHATE TRANSFER IN FROG URINARY-BLADDER". Kidney
International 33 1 (1988): 58-63. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023830190&partnerID=MN8TOARS.
Published • 10.1038/ki.1988.9
- Cancela, L.; Nemere, I.; Norman, A.W.. "1a,25 (OH)2 vitamin D3: A steroid hormone capable of producing pleiotropic receptor-mediated
biological responses by both genomic and nongenomic mechanisms". Journal of Steroid Biochemistry 30 1-6 (1988): 33-39.
http://www.scopus.com/inward/record.url?eid=2-s2.0-0023777632&partnerID=MN8TOARS.
Published • 10.1016/0022-4731(88)90073-8
- De Vernejoul, M.C.; Benamout, M.P.; Cancela, L.; Miravet, L.; Kuntz, D.; Gueris, J.; Gardin, J.P.. "Primary hyperparathyroidism
seen in rheumatology. Clinical manifestations and relationship between bone history and biological parameters". Revue du
Rhumatisme et des Maladies Osteo-Articulaires 55 7 (1988): 489-494. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024005167&partnerID=MN8TOARS.
Published
- Minghetti, P.P.; Cancela, L.; Fujisawa, Y.; Theofan, G.; Norman, A.W.. "Molecular structure of the chicken vitamin D-induced
calbindin-D(28K) gene reveals eleven exons, six Ca2+-binding domains, and numerous promoter regulatory elements". Molecular
Endocrinology 2 4 (1988): 355-367. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023879973&partnerID=MN8TOARS.
Open access
- Rebut-Bonneton, C.; Ly, S.Y.; Cancela, L.. "Calcium-transport in quiescent and 1,25-dihydroxycholecalciferol-stimulated human
osteosarcoma cells. Role in 24 hydroxylase enhancement". Hormone and Metabolic Research 20 6 (1988): 339-343. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023941120&partnerID=MN8TOARS.
Published
- Cancela, L.; Rebut-Bonneton, C.. "Regulation of 24-hydroxylase activity in mouse skin fibroblasts by cholecalciferol derivatives,
triamcinolone acetonide and a calcium modulating agent, nicardipine". Journal of Steroid Biochemistry 28 5 (1987):
479-484. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023604856&partnerID=MN8TOARS.
Published • 10.1016/0022-4731(87)90505-X
- Cancela, L.; Marie, P.J.; Le Boulch, N.; Miravet, L.. "Lack of biological activity of vitamin D3-3ß sulfate during lactation
in vitamin D-deficient rats". Reproduction Nutrition Developpement 27 6 (1987): 979-997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023502969&partnerID=MN8TOARS.
Published
- Le Boulch, N.; Cancela, L.; Miravet, L.; Lange, C.. "Assessment of vitamin D sulphate in human milk using desorption chemical
ionization mass spectrometry". Biomedical Mass Spectrometry 13 2 (1986): 53-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022572865&partnerID=MN8TOARS.
Published
- Gruson, M.; Cancela, L.; Denne, M.A.; Miravet, L.. "Relationship between bone GLA-protein (BGP) and calcidiol (25-hydroxycalciferol)
in serum of breast-fed infants.". Endocrinologia experimentalis 20 2-3 (1986): 329-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022759472&partnerID=MN8TOARS.
Published
- Cancela, L.; Le Boulch, N.; Miravet, L.. "Relationship between the vitamin D content of maternal milk and the vitamin D status
of nursing women and breast-fed infants". Journal of Endocrinology 110 1 (1986): 43-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022445355&partnerID=MN8TOARS.
Published
- Marie, P.J.; Cancela, L.; Le Boulch, N.; Miravet, L.. "Bone changes due to pregnancy and lactation: Influence of vitamin D
status". American Journal of Physiology - Endocrinology and Metabolism 251 4 (1986): http://www.scopus.com/inward/record.url?eid=2-s2.0-0022966994&partnerID=MN8TOARS.
Published
- Le Boulch, N.; Cancela, L.; Miravet, L.. "Calcidiol in human milk. The effect of prohormone on vitamin D status of breast
fed unsupplemented infants". Endocrinologia Experimentalis 20 2-3 (1986): 325-328. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022981264&partnerID=MN8TOARS.
Published
- Cancela, L.; Marie, P.J.; Le Boulch, N.; Miravet, L.. "Vitamin D3 3ß sulfate has less biological activity than free vitamin
D3 during pregnancy in rats". Biology of the Neonate 48 5 (1985): 274-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022271864&partnerID=MN8TOARS.
Published
- Cancela, L.; Marie, P.J.; Le Boulch, N.; Miravet, L.. "Influence of vitamin D on mineral metabolism, hormonal status and bone
histology in lactating rats and their pups". Journal of Endocrinology 105 3 (1985): 303-309. http://www.scopus.com/inward/record.url?eid=2-s2.0-0021848253&partnerID=MN8TOARS.
Published
- Rebut-Bonneton, C.; Demignon, J.; Cancela, L.; Miravet, L.. "Effect of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 maternal
loads on maternal and fetal vitamin D metabolite levels in the rat". Reproduction Nutrition Developpement 25 3 (1985):
583-590. http://www.scopus.com/inward/record.url?eid=2-s2.0-0021870967&partnerID=MN8TOARS.
Published
- Cancela, L.; Le Boulch, N.; Miravet, L.. "Action of vitamin D3-3 beta-sulfate during lactation in the rat.". World review
of nutrition and dietetics 43 (1984): 153-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-0021143980&partnerID=MN8TOARS.
Published
- de Vernejoul, M.C.; Girot, R.; Gueris, J.; Cancela, L.; Bang, S.; Bielakoff, J.; Mautalen, C.; Goldberg, D.; Miravet, L..
"Calcium phosphate metabolism and bone disease in patients with homozygous thalassemia". Journal of Clinical Endocrinology
and Metabolism 54 2 (1982): 276-281. http://www.scopus.com/inward/record.url?eid=2-s2.0-0019960606&partnerID=MN8TOARS.
Published
- Boulch, N.L.; Cancela, L.; Miravet, L.. "Cholecalciferol sulfate identification in human milk by HPLC". Steroids 39
4 (1982): 391-398. http://www.scopus.com/inward/record.url?eid=2-s2.0-0020470783&partnerID=MN8TOARS.
Published • 10.1016/0039-128X(82)90063-0
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