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Identification

Personal identification

Full name
JOSÉ FERNANDO DA ROCHA BARROS

Citation names

  • Barros, José

Author identifiers

Ciência ID
831F-E027-07F3
ORCID iD
0000-0001-6183-5050
AuthenticusID
R-000-8A2
Scopus Author Id
57195293515

Email addresses

  • josebarros@chporto.min-saude.pt (Professional)

Addresses

  • Centro Hospitalar Universitário de Santo António, ULS de Santo António, 4099-001, PORTO, PORTO, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
Education
Degree Classification
2008 - 2013
Concluded
Ciências Médicas (Doutoramento)
Major in Neurologia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Enxaqueca Hemiplégica Familiar em Famílias Portuguesas" (THESIS/DISSERTATION)
Aprovado com distinção
1980 - 1986
Concluded
Medicina (Licenciatura)
Major in Neurologia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Affiliation

Teaching in Higher Education

Category
Host institution
Employer
2017 - Current Invited Full Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 - 2017 Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Other Careers

Category
Host institution
Employer
2015/01/01 - Current Assistente graduado sénior (Médica) Centro Hospitalar Universitário de Santo António, Portugal
Centro Hospitalar Universitário de Santo António, Portugal
2004 - 2015 Assistente graduado (Médica) Centro Hospitalar Universitário de Santo António, Portugal
1995 - 2004 Assistente (Médica) Centro Hospitalar Universitário de Santo António, Portugal
Centro Hospitalar Universitário de Santo António, Portugal

Positions / Appointments

Category
Host institution
Employer
2023 - Current Membro do Conselho Científico Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Others

Category
Host institution
Employer
2022 - Current Membro do Conselho Estratégico para a Cultura da Reitoria da UP Universidade do Porto, Portugal
2016 - Current Diretor Clínico Hospitalar Centro Hospitalar Universitário de Santo António, Portugal
Centro Hospitalar Universitário de Santo António, Portugal
Outputs

Publications

Journal article
  1. Sequeiros J; Loureiro JL; Barros J. "In Memoriam: Paula Coutinho (1941-2022), a pioneer in Neurogenetics.". Journal of the neurological sciences (2023): http://europepmc.org/abstract/med/37713951.
    10.1016/j.jns.2023.120799
  2. Joana Damásio; Clara Barbot; Rui Felgueiras; Ana Filipa Brandão; José Barros; Jorge Oliveira; Jorge Sequeiros. "Early-Onset and Severe Complex Hereditary Spastic Paraplegia Caused by De Novo Variants in SPAST". Movement Disorders (2023): https://doi.org/10.1002/mds.29380.
    10.1002/mds.29380
  3. Malaquias MJ; Oliveira J; Santos M; Brandão AF; Sardoeira A; Sequeiros J; Barros J; Damásio J. "Pseudodominance in Friedreich Ataxia-Impact of High Prevalence of Carriers and Intrafamilial Clinical Variation.". Movement disorders clinical practice (2023): http://europepmc.org/abstract/med/37070055.
    10.1002/mdc3.13694
  4. Moura J; Sardoeira A; Oliveira J; Mendes A; Barros J; Sequeiros J; Barbot C; Damásio J. "Childhood-Onset Writer's Cramp in Hereditary Spastic Paraplegia Type 15.". The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (2022): http://europepmc.org/abstract/med/35538608.
    10.1017/cjn.2022.59
  5. "Abstracts from the 54th European Society of Human Genetics (ESHG) Conference: e-Posters.". European journal of human genetics : EJHG (2022): http://europepmc.org/abstract/med/35393538.
    10.1038/s41431-021-01026-1
  6. Santos M; Damásio J; Carmona S; Neto JL; Dehghani N; Guedes LC; Barbot C; et al. "Molecular Characterization of Portuguese Patients with Hereditary Cerebellar Ataxia.". Cells (2022): http://europepmc.org/abstract/med/35326432.
    10.3390/cells11060981
  7. "Rare occurrence of severe blindness and deafness in Friedreich ataxia: a case report". Cerebellum & Ataxias 8 1 (2021): http://dx.doi.org/10.1186/s40673-021-00140-6.
    10.1186/s40673-021-00140-6
  8. Damásio J; Santos M; Samões R; Araújo M; Macedo M; Sardoeira A; Cavaco S; et al. "Novel KMT2B mutation causes cerebellar ataxia: Expanding the clinical phenotype.". Clinical genetics (2021): http://europepmc.org/abstract/med/34477219.
    10.1111/cge.14055
  9. "José Pereira Monteiro, the President". Sinapse 21 1 (2021): 8-10. http://dx.doi.org/10.46531/sinapse/pe/210021/2021.
    10.46531/sinapse/pe/210021/2021
  10. "Das Doenças Humanas por Priões à COVID-19: 20 Anos de Sinapse". Sinapse 21 1 (2021): http://dx.doi.org/10.46531/sinapse/ed/210020.
    10.46531/sinapse/ed/210020
  11. Damásio J; Santos D; Sara Morais S; Brás J; Guerreiro R; Sardoeira A; Cavaco S; et al. "Congenital ataxia due to novel variant in ATP8A2.". Clinical genetics (2021): http://europepmc.org/abstract/med/33682124.
    10.1111/cge.13954
  12. Barros, J.. "Covid-19 pandemics: Mitigating an injustice,Pandemia covid-19: Mitigação de uma injustiça". Sinapse 20 2 (2020): 5-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097828020&partnerID=MN8TOARS.
    10.46531/sinapse/ED/COVID19/BarrosJ/2020
  13. Calejo M; Salgado P; Moreira B; Correia C; Barros J. "Botulinum Toxin Type A Injections as an Effective Treatment of Refractory Multiple Sclerosis-Related Trigeminal Pain - A Case Report.". Headache (2019): http://europepmc.org/abstract/med/31424566.
    10.1111/head.13609
  14. Barros, J.. "Luís de Carvalho, a great public servant,Luís de Carvalho, Grande servidor public". Sinapse 16 1 (2016): 55-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026802942&partnerID=MN8TOARS.
  15. Barros J; Ferreira A; Brandão AF; Lemos C; Correia F; Damásio J; Tuna A; et al. "Familial hemiplegic migraine due to L263V SCN1A mutation: discordance for epilepsy between two kindreds from Douro Valley.". Cephalalgia : an international journal of headache (2014): http://europepmc.org/abstract/med/24646837.
    10.1177/0333102414527015
  16. Barros J; Ruano L; Domingos J; Tuna A; Damásio J; Alonso I; Silveira I; Sequeiros J; Coutinho P. "The prevalence of familial hemiplegic migraine with cerebellar ataxia and spinocerebellar ataxia type 6 in Portugal.". Headache (2013): http://europepmc.org/abstract/med/24898624.
    10.1111/head.12260
  17. Barros J; Barreto R; Brandão AF; Domingos J; Damásio J; Ramos C; Lemos C; et al. "Monozygotic twin sisters discordant for familial hemiplegic migraine.". The journal of headache and pain (2013): http://europepmc.org/abstract/med/24041236.
    10.1186/1129-2377-14-77
  18. Quintas M; Neto JL; Pereira-Monteiro J; Barros J; Sequeiros J; Sousa A; Alonso I; Lemos C. "Interaction between ¿-aminobutyric acid A receptor genes: new evidence in migraine susceptibility.". PloS one (2013): http://europepmc.org/abstract/med/24040174.
    10.1371/journal.pone.0074087
  19. Coutinho P; Ruano L; Loureiro JL; Cruz VT; Barros J; Tuna A; Barbot C; et al. "Hereditary ataxia and spastic paraplegia in Portugal: a population-based prevalence study.". JAMA neurology (2013): http://europepmc.org/abstract/med/23609960.
    10.1001/jamaneurol.2013.1707
  20. Barros J; Damásio J; Tuna A; Alves I; Silveira I; Pereira-Monteiro J; Sequeiros J; et al. "Cerebellar ataxia, hemiplegic migraine, and related phenotypes due to a CACNA1A missense mutation: 12-year follow-up of a large Portuguese family.". JAMA neurology (2013): http://europepmc.org/abstract/med/23407676.
    10.1001/jamaneurol.2013.591
  21. Quintas M; Neto J; Pereira-Monteiro J; Barros J; Sequeiros J; Sousa A; Alonso I; Lemos C. "Unraveling migraine susceptibility in females: the involvement of GABA genes". The journal of headache and pain (2013): http://europepmc.org/abstract/PMC/PMC3619994.
  22. Nogueira, C.; Barros, J.; Sá, M.J.; Azevedo, L.; Taipa, R.; Torraco, A.; Meschini, M.C.; et al. "Novel TTC19 mutation in a family with severe psychiatric manifestations and complex III deficiency". Neurogenetics 14 2 (2013): 153-160. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877726828&partnerID=MN8TOARS.
    10.1007/s10048-013-0361-1
  23. Lemos C; Alonso I; Barros J; Sequeiros J; Pereira-Monteiro J; Mendonça D; Sousa A. "Assessing risk factors for migraine: differences in gender transmission.". PloS one (2012): http://europepmc.org/abstract/med/23185642.
    10.1371/journal.pone.0050626
  24. Barros J; Mendes A; Matos I; Pereira-Monteiro J. "Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2).". The journal of headache and pain (2012): http://europepmc.org/abstract/med/22661290.
    10.1007/s10194-012-0462-5
  25. Barros J; Damásio J; Tuna A; Pereira-Monteiro J. "Migraine-induced epistaxis and sporadic hemiplegic migraine: unusual features in the same patient.". Case reports in neurology (2012): http://europepmc.org/abstract/med/22807908.
    10.1159/000339824
  26. Monteiro C; Barros J; Taipa R; Pereira-Monteiro J. "Sporadic hemiplegic migraine with normal imaging as the initial manifestation of CADASIL.". Cephalalgia : an international journal of headache (2012): http://europepmc.org/abstract/med/22250206.
    10.1177/0333102411434809
  27. Lemos C; Neto JL; Pereira-Monteiro J; Mendonça D; Barros J; Sequeiros J; Alonso I; Sousa A. "A role for endothelin receptor type A in migraine without aura susceptibility? A study in Portuguese patients.". European journal of neurology (2010): http://europepmc.org/abstract/med/20964792.
    10.1111/j.1468-1331.2010.03239.x
  28. Lemos C; Mendonça D; Pereira-Monteiro J; Barros J; Sequeiros J; Alonso I; Sousa A. "BDNF and CGRP interaction: implications in migraine susceptibility.". Cephalalgia : an international journal of headache (2010): http://europepmc.org/abstract/med/20959432.
    10.1177/0333102410368443
  29. Lemos C; Pereira-Monteiro J; Mendonça D; Ramos EM; Barros J; Sequeiros J; Alonso I; Sousa A. "Evidence of syntaxin 1A involvement in migraine susceptibility: a Portuguese study.". Archives of neurology (2010): http://europepmc.org/abstract/med/20385907.
    10.1001/archneurol.2010.37
  30. Castro MJ; Stam AH; Lemos C; de Vries B; Vanmolkot KR; Barros J; Terwindt GM; et al. "First mutation in the voltage-gated Nav1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy.". Cephalalgia : an international journal of headache (2009): http://europepmc.org/abstract/med/19220312.
    10.1111/j.1468-2982.2008.01721.x
  31. Lemos C; Castro MJ; Barros J; Sequeiros J; Pereira-Monteiro J; Mendonça D; Sousa A. "Familial clustering of migraine: further evidence from a Portuguese study.". Headache (2008): http://europepmc.org/abstract/med/18624713.
    10.1111/j.1526-4610.2008.01177.x
  32. Castro MJ; Nunes B; de Vries B; Lemos C; Vanmolkot KR; van den Heuvel JJ; Temudo T; et al. "Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes.". Clinical genetics (2007): http://europepmc.org/abstract/med/18028456.
    10.1111/j.1399-0004.2007.00918.x
  33. Castro MJ; Stam AH; Lemos C; Barros J; Gouveia RG; Martins IP; Koenderink JB; et al. "Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine.". Journal of human genetics (2007): http://europepmc.org/abstract/med/17952365.
    10.1007/s10038-007-0205-7
  34. Costa MDC; Teixeira-Castro A; Constante M; Magalhães M; Magalhães P; Cerqueira J; Vale J; et al. "Exclusion of mutations in the PRNP, JPH3, TBP, ATN1, CREBBP, POU3F2 and FTL genes as a cause of disease in Portuguese patients with a Huntington-like phenotype.". Journal of human genetics (2006): http://europepmc.org/abstract/med/16858508.
    10.1007/s10038-006-0001-9
  35. Alonso I; Barros J; Tuna A; Seixas A; Coutinho P; Sequeiros J; Silveira I. "A novel R1347Q mutation in the predicted voltage sensor segment of the P/Q-type calcium-channel alpha-subunit in a family with progressive cerebellar ataxia and hemiplegic migraine.". Clinical genetics (2004): http://europepmc.org/abstract/med/15032980.
    10.1111/j..2004.00187.x
  36. Alonso I; Barros J; Tuna A; Coelho J; Sequeiros J; Silveira I; Coutinho P. "Phenotypes of spinocerebellar ataxia type 6 and familial hemiplegic migraine caused by a unique CACNA1A missense mutation in patients from a large family.". Archives of neurology (2003): http://europepmc.org/abstract/med/12707077.
    10.1001/archneur.60.4.610
  37. Silveira I; Miranda C; Guimarães L; Moreira MC; Alonso I; Mendonça P; Ferro A; et al. "Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n allele at the SCA17 locus.". Archives of neurology (2002): http://europepmc.org/abstract/med/11939898.
    10.1001/archneur.59.4.623
  38. Maciel P; Costa MC; Ferro A; Rousseau M; Santos CS; Gaspar C; Barros J; et al. "Improvement in the molecular diagnosis of Machado-Joseph disease.". Archives of neurology (2001): http://europepmc.org/abstract/med/11708990.
    10.1001/archneur.58.11.1821
  39. Moreira MC; Barbot C; Tachi N; Kozuka N; Uchida E; Gibson T; Mendonça P; et al. "The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin.". Nature genetics (2001): http://europepmc.org/abstract/med/11586300.
    10.1038/ng1001-189
  40. Barbot C; Coutinho P; Chorão R; Ferreira C; Barros J; Fineza I; Dias K; et al. "Recessive ataxia with ocular apraxia: review of 22 Portuguese patients.". Archives of neurology (2001): http://europepmc.org/abstract/med/11176957.
    10.1001/archneur.58.2.201
  41. Moreira MC; Barbot C; Tachi N; Kozuka N; Mendonça P; Barros J; Coutinho P; Sequeiros J; Koenig M. "Homozygosity mapping of Portuguese and Japanese forms of ataxia-oculomotor apraxia to 9p13, and evidence for genetic heterogeneity.". American journal of human genetics (2001): http://europepmc.org/abstract/med/11170899.
    10.1086/318191
  42. Silveira I; Alonso I; Guimarães L; Mendonça P; Santos C; Maciel P; Fidalgo De Matos JM; et al. "High germinal instability of the (CTG)n at the SCA8 locus of both expanded and normal alleles.". American journal of human genetics (2000): http://europepmc.org/abstract/med/10712199.
    10.1086/302827
  43. Coutinho P; Barros J; Zemmouri R; Guimarães J; Alves C; Chorão R; Lourenço E; et al. "Clinical heterogeneity of autosomal recessive spastic paraplegias: analysis of 106 patients in 46 families.". Archives of neurology (1999): http://europepmc.org/abstract/med/10448799.
    10.1001/archneur.56.8.943
  44. Sousa A; Coelho T; Barros J; Sequeiros J. "Genetic epidemiology of familial amyloidotic polyneuropathy (FAP)-type I in Póvoa do Varzim and Vila do Conde (north of Portugal).". American journal of medical genetics (1995): http://europepmc.org/abstract/med/8825887.
    10.1002/ajmg.1320600606
  45. Nunes, B.; Barros, J.; Correia, M.; Lopes, J.C.. "Epilepsy and cerebrovascular diseases in an outpatient clinic". Cerebrovascular Diseases 4 2 (1994): 96-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141860486&partnerID=MN8TOARS.
    10.1159/000108460
Preprint
  1. Damásio J; Sardoeira A; Araújo M; Carvalho I; Sequeiros J; Barros J. "Blindness and Deafness – an Extreme Phenotype in Friedreich Ataxia". 2021. http://europepmc.org/abstract/PPR/PPR354188.
    10.21203/rs.3.rs-573040/v1
Activities

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2016 - Current Componente Curricular "Dissertação/ Projeto/Estágio" Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 - 2017 Clínica Neurológica Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal