Lisete Machado e Silva (821E-7470-0086)

Curriculum Vitae

Lisete Machado e Silva

Lisete is a Researcher at the Department of Chemistry and Biochemistry at Faculty of Sciences University of Porto (FCUP), Portugal, since September 2023. She is also an Honorary Research Associate in the Glycosciences Laboratory at Imperial College London (ICL), since 2019. Lisete obtained her BSc degree in Chemistry in 2007 at FCUP, and completed her MSc in Chemistry with food specialisation in 2008, at the same University. Her PhD degree in Biochemistry was obtained in 2014 at University of Aveiro (UA), in collaboration with the GlycoLab: Functional Glycobiology at FCT-NOVA (Lisbon, Portugal) and the Glycosciences Laboratory. PhD IN BIOCHEMISTRY: Lisete focused on the structural analyses of lipopolysaccharides (LPS) from clinical isolates of H. pylori by GC-MS and ESI-MSn, and on the development of a bacterial LPS microarray for interaction studies with glycan-binding proteins and human sera. POST-DOCTORAL STUDIES IN GLYCOBIOLOGY AND BIOCHEMISTRY: Her knowledge on the structural (bio)chemistry of complex carbohydrates, combined with her passion for the glycobiology field and expertise on glycan microarrays, have led her to a Research Associate position in the pioneer glycan microarray team (Glycosciences Lab.) at ICL, in March 2015; and in November 2015, she was named Deputy Microarray Project Leader and had a leading role in the Facility management. In parallel, Lisete carried out investigations of different liposomal formulations for lipid-linked glycan probes in neoglycolipid (NGL)-based microarrays with respect to the binding signals they elicit in microarray analyses. These studies led to the construction of a new version of a broad-spectrum microarray of ~ 1000 natural or synthetic lipid-linked sequence-defined glycan probes (one of the two largest glycan libraries in the world) for the Wellcome-Trust supported Carbohydrate Microarray Facility, suitable for screening analyses of a variety of carbohydrate recognition systems of biological and medical impact and able to serve the scientific community as international resources. During 2015-2019, Lisete actively contributed and provided leadership support to biotechnology and biomedicine R&D projects (translational research); collaborated with 50+ national and international academic and industrial teams that have resulted in > £30k of revenue for facility services. As an Honorary Research Associate in the Glycosciences Laboratory, Lisete is currently providing consultancy advice to the group regarding microarray equipment and training to the new staff members, assisting with microarray experiments, data analysis and preparation of manuscripts. Back to UA (2019-2022), Lisete’s work focused on the development of galactomannan-based microparticles, obtained from different natural sources, for pulmonary drug delivery. The structural variability of the different galactomannans was evaluated using conventional analytical tools and complemented with interaction studies with glycan-binding proteins of various recognition systems using glycan microarrays. Currently, at FCUP, Lisete is a team member of the research project “InsectERA - The ERA of the insect industry”. This Mobilizing Agenda for Business Innovation, framed in the Portuguese Recovery and Resilience Plan (PRR) aims to enable the industrialization and commercialization of innovative products based on insects, both in the food area (animal and human food), as well as in other industries (cosmetics or bioplastics) or in the innovative sector of bioremediation. Aiming to use insects as a healthy and sustainable alternative nutritional source in new product lines for human consumption, Lisete is focused on the extraction and characterization of the protein profile from different insect-derived flours, and on the evaluation of the insect protein digestibility, their potential allergenicity and immunogenicity.

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Identification

Personal identification

Full name: Lisete Machado e Silva
Gender: Female

Citation names

Silva, Lisete M.
Silva, Lisete
Silva, L
Silva, LM

Author identifiers

Ciência ID: 821E-7470-0086
ORCID iD: 0000-0003-4876-5240
Researcher Id: AAD-7415-2020
Scopus Author Id: 35335398300

Email addresses

lisete.silva@fc.up.pt (Professional)

Addresses

Glycosciences Laboratory , Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Burlington Danes Building Hammersmith Campus, Du Cane Rd, W12 0NN, London , London , United Kingdom (Professional)
Rua do Campo Alegre, s/n, 4169-007, Porto, Porto, Portugal (Professional)

Websites

http://www.imperial.ac.uk/people/l.machado-e-silva (Professional)
https://laqv.requimte.pt/people/2477-lisete_m_silva (Professional)
https://www.foodphenolab.com/ (Professional)

Knowledge fields

Natural sciences - Biological Sciences - Biochemistry

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)

Education

	Degree	Classification
2018/11 Attended	Annual Immunology Short Course for Clinicians and Scientists (Outros) Major in Course Imperial College London, United Kingdom
2018 Attended	Mental Health First Aid course (Outros) Major in Course Imperial College London, United Kingdom
2018 Attended	How Intellectual Property Rights Can Impact Your Research - Course (Outros) Major in Course Imperial College London, United Kingdom
2014 Concluded	Biochemistry (Doutoramento) Major in Biochemistry (clinical branch) Universidade de Aveiro, Portugal "Structural analysis of glycans and development of microarrays from Helicobacter pylori cell surface glycome." (THESIS/DISSERTATION)	Approved by unanimity
2008 Concluded	Chemistry (Mestrado) Major in Food branch Universidade do Porto Faculdade de Ciências, Portugal "Evaluation of the oxidative stability of vegetable oils and olive oil compounds with anti-atherosclerotic activity during food processing. " (THESIS/DISSERTATION)	18/20
2007 Concluded	Chemistry (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal "Isolation of olive oil compounds with anti-atherosclerotic activity during roasted food processing." (THESIS/DISSERTATION)	14/20

Affiliation

Science

	Category Host institution	Employer
2023/09/01 - Current	Researcher (Research)	Universidade do Porto Faculdade de Ciências, Portugal
	Universidade do Porto Faculdade de Ciências, Portugal
2019 - Current	Visiting Researcher (Research)	Imperial College London Glycosciences Laboratory, United Kingdom
	Imperial College London Glycosciences Laboratory, United Kingdom
2019/04/01 - 2022/06/30	Researcher (Research)	Universidade de Aveiro, Portugal
	Universidade de Aveiro, Portugal
2015/03 - 2019/04	Researcher (Research)	Imperial College London Glycosciences Laboratory, United Kingdom

2009/05 - 2010/08	Research Trainee (Research)	Universidade de Aveiro, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2015 - 2019	Lecturer (University Teacher)	Imperial College London, United Kingdom

Projects

Grant

	Designation	Funders
2018/09 - 2021/08	GLYCOINTERACT: Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition PTDC/BIA-MIB/31730/2017	Fundação para a Ciência e a Tecnologia Concluded
2016/06 - 2017	Chikungunya Virus Replication and Pathogenesis R01AI123348 Researcher	National Institute of Allergy and Infectious Diseases
2013/07 - 2014/12	Pylori GlycoArrays: Development of microarrays from Helicobacter pylori cell surface glycome toward immunological and serological studies EXPL/BBB-BQB/0750/2012	Fundação para a Ciência e a Tecnologia

Contract

	Designation	Funders
2023/09/01 - Current	InsectERA - The ERA of the insect industry C644917393-00000032 Researcher Universidade do Porto Faculdade de Ciências, Portugal	Ongoing
2019/04/01 - 2022/06/30	PulManCar: Microparticles design for active compounds pulmonary delivery using insulin as model POCI-01-0145-FEDER-029560 Researcher Universidade de Aveiro, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/07/01 - 2022/06/30	Microparticles design for active compounds pulmonary delivery using insulin as model PTDC/EQU-EPQ/29560/2017 Universidade de Aveiro, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2019/01/01 - 2019/12/31	Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos UID/QUI/50006/2019 LA/P/0008/2020 10.54499/LA/P/0008/2020 Universidade do Porto Faculdade de Ciências, Portugal Universidade Nova de Lisboa, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade de Aveiro, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade de Évora, Portugal Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal Universidade de Lisboa Instituto Dom Luiz, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/04 - 2019/03	Host-microbiota interactions in the pathology of preterm birth 22-FY18-82 Researcher Imperial College London - Hammersmith Campus, United Kingdom	Concluded
2015/08 - 2018/08	Carbohydrate Microarray Facility for Biomedical Exploitation WT108430 Researcher	Wellcome Trust
2017/05 - 2018/04	Guillain Barre syndrome antibodies during Zika and Chikungunya vaccine trials 87242-544164 Researcher Imperial College London - Hammersmith Campus, United Kingdom	Innovate UK Concluded
2015/10 - 2016/10	Chemo-enzymatic production of specialty glycans BB/M028941/1 Researcher	Biotechnology and Biological Sciences Research Council
2011/01/01 - 2012/12/31	Strategic Project - UI 62 - 2011-2012 PEst-C/QUI/UI0062/2011 Universidade de Aveiro, Portugal Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book chapter	Silva, Lisete; Shahidi, Fereidoon; Coimbra, Manuel A.. "Dried Pears: Phytochemicals and Potential Health Effects". In Dried Fruits, 325-356. Blackwell Publishing Ltd., 2013. Published • 10.1002/9781118464663.ch18 Ferreira, José; Silva, Lisete; Monteiro, Mario; Coimbra, Manuel A.. "Helicobacter pylori cell-surface glycans structural features: Role in gastric colonization, pathogenesis, and carbohydrate-based vaccines". 160-193. 2011. Published • 10.1039/9781849732765-00160 Silva, Lisete M.. "Isolamento e caracterização estrutural de polissacarídeos pécticos da pêra passa de Viseu". In Secagem de Peras. Da tradição à ciência, 205-2014. Viseu, Portugal: CI&DETS, Viseu, 2010. Published
Conference abstract	Valente, Sara; Lopes, Guido R.; Silva, Lisete; Almeida, Margarida; Ferreira, Paula; Coimbra, Manuel A.; Passos, Cláudia. "Spent coffee grounds as a food byproducts source of polysaccharide with application as carriers for pulmonary insulin delivery". Paper presented in Dare2Change conference, Porto, 2021. Valente, Sara; Lopes, Guido R.; Silva, Lisete; Almeida, Margarida; Ferreira, Paula; Coimbra, Manuel A.; Passos, Cláudia. "FROM SPENT COFFEE GROUNDS TO POLYSACCHARIDE-BASED MICROPARTICLES FOR PULMONARY INSULIN DELIVERY". Paper presented in Waste2Value International Congress, Online, 2021. Valente, Sara A.; Silva, Lisete M.; Lopes, Guido R.; Almeida, Margarida; Coimbra, Manuel A.; Passos, Claudia P.. "Development of galactomannan-based microparticles for pulmonary insulin delivery". Paper presented in 7th Portuguese Young Chemists Meeting, Online, 2021. Valente, Sara A.; Silva, Lisete M.; Lopes, Guido R.; Almeida, Margarida; Coimbra, Manuel A.; Passos, Claudia P.. "Development of polysaccharide-based carriers for pulmonary insulin delivery". Paper presented in 4th EPNOE Junior Scientist Meeting, Online, 2021. Correia, Viviana G.; Costa, Raquel L.; Trovão, Filipa; Andrade Pinheiro, Benedita; Brás, Joana L. A.; Liu, Y.; Silva, Lisete M.; et al. "Functional and structural characterization of human microbiome systems for glycan recognition in the gut.". Paper presented in 9th ITQB NOVA PhD Students Meeting., Oeiras, 2018.
Conference paper	Akune, Yukie; Aspinar, Sena; Silva, Lisete; Stoll, Mark; Palma, Angelina S.; Liu, Yan; Ranzinger, Rene; Feizi, Ten. "CarbArrayART: Carbohydrate Array Analysis and Reporting Tool New software for glycan array for data processing, storage and presentation". Paper presented in Annual Meeting of the Society for Glycobiology, New Orleans, LA, 2018. Published Akune, Yukie; Arpinar, Sena; Stoll, Mark; Silva, Lisete; Palma, Angelina S.; Liu, Yan; Ranzinger, Rene; Feizi, Ten. "New software for glycan array for data processing, storage and presentation". Paper presented in Annual Meeting of the Society for Glycobiology, Portland, OR, 2017. Published Correia, Viviana G.; Brás, Joana Luís Armada; Liu, Yan; Silva, Lisete; Zhang, Yibing; Pinheiro, Benedita; Romão, Maria João C.; et al. "An integrative strategy to decipher glycan recognition in the human gut microbiome.". Paper presented in Annual Meeting of the Society for Glycobiology, New Orleans, LA, 2016. Published Silva, Lisete M.; Childs, R.A.; Palma, Angelina S.; Chai, Wengang; Feizi, Ten; Liu, Yan. "Influence of carrier lipid composition on glycan recognition in NGL-based microarrays.". Paper presented in Annual Meeting of the Society for Glycobiology, San Francisco, CA, 2015. Published
Conference poster	Silva, Lisete M.. Corresponding author: Silva, Lisete M.. "Extraction and characterization of insect proteins: a sustainable food alternative". Paper presented in 1st InsectERA Meeting, 2024. Fernandes, Pedro A. R.; Joana Martins; Inês Pina; Silva, Lisete M.; Diogo Figueira; Castelo-Branco, Diogo; Coimbra, Manuel. "The role of polysaccharides towards aquafaba as an effective animal protein alternative". Paper presented in 7th Iberian Carbohydrate Meeting, 2024. Bárbara Oliveira; Silva, Lisete M.; Coimbra, Manuel A.. "THE NATURE OF CARBOHYDRATES AND PHENOLIC COMPOUNDS IN POMEGRANATE SKINS". Paper presented in XV Portuguese Meeting in Food Chemistry, 2021. Bastos, Rita; Martins, Vítor J.; Sérgio Viduêdo; Reis, Sofia F.; Gaspar, Vítor M.; Mano, Joao F.; Silva, Lisete M.; Coimbra, Manuel A.. "Yeast4FoodMed- Valuation of brewer's spent yeast polysaccharides for food and biomedical applications". Paper presented in Dare2Change-Innovation Driven Agrifood Business, 2021. Trovão, Filipa; Correia, Viviana G.; Lourenço, Frederico; Brás, Joana L. A.; Silva, Lisete M.; Paulsen, Berit S.; Feizi, Ten; et al. "Characterisation of a novel CBM from human gut microbiota provides further insight into the bacterial degradation of complex pectic polysaccharides.". Paper presented in 22nd EMBL PhD Symposium: The Roaring 20s, 2020. Passos, Cláudia; Silva, Lisete M.. "Preparation of microparticles for pulmonary administration of insulin using coffee polysaccharides as protein carriers.". Paper presented in 6th EPNOE International Polysaccharide Conference, 2019. Silva, Lisete M.; Rocha, Júlio; Lopes, Guido R.; Bastos, Ana; Almeida, Margarida; Coimbra, Manuel A.; Passos, Claudia P.. "Microwave effect on the physicochemical properties of Locust bean gum microparticles - preparation for application in pulmonary drug delivery". Paper presented in 6th EPNOE - International Polysaccharide Conference, 2019. Correia, Viviana G.; Lourenço, Frederico; Trovão, Filipa; Brás, Joana L. A.; Andrade Pinheiro, Benedita; Silva, Lisete M.; Feizi, Ten; et al. "A novel pectin binding protein from the human gut microbiota". Paper presented in 7th National Meeting of Portuguese Users of Synchrotron Radiation (ENURS), 2018. Silva, Lisete; Moreira, Ana S. P.; Domingues, M. Rosário M.; Palma, A.; José Alexandre Ferreira; Coimbra, M. A.. "Helicobacter pylori cell-surface glycans: Occurrence and structural insights towards development of a novel pathogen microarray". Paper presented in International conference on challenges in chemistry and biology of carbohydrates (CARBO-XXVIII), 2014.
Journal article	Miguel F. Galrinho; Lisete M. Silva; Guido R. Lopes; Bernardo A.C. Ferreira; Sara A. Valente; Isabel Ferreira; Benedita A. Pinheiro; et al. "The study of galactomannans with different molecular weights and their ability to form microparticles suitable for pulmonary delivery". Carbohydrate Polymers (2024): http://dx.doi.org/10.1016/j.carbpol.2024.122268. 10.1016/j.carbpol.2024.122268 Sofia F. Reis; Susana Messias; Rita Bastos; Vítor J. Martins; Viviana G. Correia; Benedita A. Pinheiro; Lisete M. Silva; et al. "Structural differences on cell wall polysaccharides of brewer's spent Saccharomyces and microarray binding profiles with immune receptors". Carbohydrate Polymers (2023): http://dx.doi.org/10.1016/j.carbpol.2022.120325. 10.1016/j.carbpol.2022.120325 Marie N. Sorin; Antonio Di Maio; Lisete M. Silva; Domenic Ebert; Clément P. Delannoy; Ngoc-Khanh Nguyen; Yann Guerardel; et al. "Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus". Cell Reports (2023): http://dx.doi.org/10.1016/j.celrep.2023.112114. 10.1016/j.celrep.2023.112114 Meriam Shahin; Devon Sheppard; Claire Raynaud; Jamie-Lee Berry; Ishwori Gurung; Lisete M. Silva; Ten Feizi; Yan Liu; Vladimir Pelicic. "Characterisation of a glycan-binding complex of minor pilins completes the analysis of Streptococcus sanguinis type 4 pili subunits". Proceedings of the National Academy of Sciences (2023): http://dx.doi.org/10.1073/pnas.2216237120. 10.1073/pnas.2216237120 Sofia F. Reis; Vítor J. Martins; Rita Bastos; Tânia Lima; Viviana G. Correia; Benedita Pinheiro; Lisete M. Silva; et al. "Feasibility of Brewer's Spent Yeast Microcapsules as Targeted Oral Carriers". Foods (2023): http://dx.doi.org/10.3390/foods12020246. 10.3390/foods12020246 Yukie Akune; Sena Arpinar; Lisete M Silva; Angelina S Palma; Virginia Tajadura-Ortega; Kiyoko F Aoki-Kinoshita; René Ranzinger; Yan Liu; Ten Feizi. "CarbArrayART: a new software tool for carbohydrate microarray data storage, processing, presentation, and reporting". Glycobiology (2022): https://doi.org/10.1093/glycob/cwac018. 10.1093/glycob/cwac018 Valente, Sara A.; Silva, Lisete M.; Lopes, Guido R.; Sarmento, Bruno; Coimbra, Manuel A.; Passos, Cláudia P.. "Polysaccharide-based formulations as potential carriers for pulmonary delivery - A review of their properties and fates". Carbohydrate Polymers 277 (2022): 118784. http://dx.doi.org/10.1016/j.carbpol.2021.118784. Published • 10.1016/j.carbpol.2021.118784 Viviana G. Correia; Filipa Trovão; Benedita A. Pinheiro; Joana L. A. Brás; Lisete M. Silva; Cláudia Nunes; Manuel A. Coimbra; et al. "Mapping Molecular Recognition of ß1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus". Microbiology Spectrum 9 3 (2021): https://doi.org/10.1128/Spectrum.01826-21. Published • 10.1128/Spectrum.01826-21 Li, Chunxia; Palma, Angelina S; Zhang, Pengtao; Zhang, Yibing; Gao, Chao; Silva, Lisete M; Li, Zhen; et al. "Noncovalent microarrays from synthetic amino-terminating glycans: Implications in expanding glycan microarray diversity and platform comparison". Glycobiology 31 8 (2021): 931-946. http://dx.doi.org/10.1093/glycob/cwab037. Open access • Published • 10.1093/glycob/cwab037 Lisete M. Silva; Viviana G. Correia; Ana S.P. Moreira; Maria Rosário M. Domingues; Rui M. Ferreira; Céu Figueiredo; Nuno F. Azevedo; et al. Corresponding author: Lisete M. Silva. "Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays". Carbohydrate Polymers (2020): 117350-117350. https://doi.org/10.1016/j.carbpol.2020.117350. Open access • Published • 10.1016/j.carbpol.2020.117350 Nicole McAllister; Yan Liu; Lisete M. Silva; Anthony J. Lentscher; Wengang Chai; Nian Wu; Kira A. Griswold; et al. "Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglycans as attachment factors". Journal of Virology (2020): https://doi.org/10.1128/JVI.01500-20. Published • 10.1128/JVI.01500-20 Vendele, Ingrida; Willment, Janet A.; Silva, Lisete M.; Palma, Angelina S.; Chai, Wengang; Liu, Yan; Feizi, Ten; et al. "Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls". PLOS Pathogens 16 1 (2020): e1007927. http://dx.doi.org/10.1371/journal.ppat.1007927. Published • 10.1371/journal.ppat.1007927 Wu, N.; Silva, L.M.; Liu, Y.; Zhang, Y.; Gao, C.; Zhang, F.; Fu, L.; et al. "Glycan markers of human stem cells assigned with beam search arrays". Molecular and Cellular Proteomics 18 10 (2019): 1981-2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072849227&partnerID=MN8TOARS. Published • 10.1074/mcp.RA119.001309 Chandra, N.; Liu, Y.; Liu, J.-X.; Frängsmyr, L.; Wu, N.; Silva, L.M.; Lindström, M.; et al. "Sulfated glycosaminoglycans as viral decoy receptors for human adenovirus type 37". Viruses 11 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85062951333&partnerID=MN8TOARS. Published • 10.3390/v11030247 Rudkin, F.M.; Raziunaite, I.; Workman, H.; Essono, S.; Belmonte, R.; MacCallum, D.M.; Johnson, E.M.; et al. "Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis". Nature Communications 9 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058242231&partnerID=MN8TOARS. Published • 10.1038/s41467-018-07738-1 Loureiro, L.R.; Sousa, D.P.; Ferreira, D.; Chai, W.; Lima, L.; Pereira, C.; Lopes, C.B.; et al. "Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2–6 sialic acids". Scientific Reports 8 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85051658578&partnerID=MN8TOARS. Published • 10.1038/s41598-018-30421-w Li, Z.; Gao, C.; Zhang, Y.; Palma, A.S.; Childs, R.A.; Silva, L.M.; Liu, Y.; et al. "O-glycome beam search arrays for carbohydrate ligand discovery". Molecular and Cellular Proteomics 17 1 (2018): 121-133. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040257214&partnerID=MN8TOARS. Published • 10.1074/mcp.RA117.000285 Liu, Y.; McBride, R.; Stoll, M.; Palma, A.S.; Silva, L.; Agravat, S.; Aoki-Kinoshita, K.F.; et al. "The minimum information required for a glycomics experiment (MIRAGE) project: Improving the standards for reporting glycan microarray-based data". Glycobiology 27 4 (2017): 280-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019624012&partnerID=MN8TOARS. Published • 10.1093/glycob/cww118 Nunes, C.; Silva, L.; Fernandes, A.P.; Guiné, R.P.F.; Domingues, M.R.M.; Coimbra, M.A.. "Occurrence of cellobiose residues directly linked to galacturonic acid in pectic polysaccharides". Carbohydrate Polymers 87 1 (2012): 620-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054737677&partnerID=MN8TOARS. Published • 10.1016/j.carbpol.2011.08.027 Silva, Lisete M.; Pinto, Joana; Carrola, Joana; Paiva-Martins, Fátima. "Oxidative stability of olive oil after food processing and comparison with other vegetable oils". Food Chemistry 121 4 (2010): 1177-1187. http://dx.doi.org/10.1016/j.foodchem.2010.02.001. Published • 10.1016/j.foodchem.2010.02.001 Paiva-Martins, F.; Fernandes, J.; Santos, V.; Silva, Lisete; Borges, F.; Rocha, S.; Belo, L.; Santos-Silva, A.. "Powerful Protective Role of 3,4-Dihydroxyphenylethanol-Elenolic Acid Dialdehyde against Erythrocyte Oxidative-Induced Hemolysis". Journal of Agricultural and Food Chemistry 58 1 (2010): 135-140. http://dx.doi.org/10.1021/jf9031052. Published • 10.1021/jf9031052 Silva, L.; Garcia, B.; Paiva-Martins, F.. "Oxidative stability of olive oil and its polyphenolic compounds after boiling vegetable process". LWT - Food Science and Technology 43 9 (2010): 1336-1344. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954027971&partnerID=MN8TOARS. Published • 10.1016/j.lwt.2010.05.013
Preprint	Nils H. Rustmeier; Lisete M. Silva; Antonio Di Maio; Joshua C. Müller; Alexander Herrmann; Ten Feizi; Yan Liu; Thilo Stehle. "A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus". 2023. https://doi.org/10.1101/2023.04.10.536218. 10.1101/2023.04.10.536218
Thesis / Dissertation	Silva, Lisete Machado e. "Structural analysis of glycans and development of microarrays from Helcobacter pylori cell surface glycome". PhD, 2014. http://hdl.handle.net/10773/15453. Silva, Lisete Machado e. "Determinação da estabilidade de óleos e de compostos com actividade anti-aterosclerótica do azeite durante o processamento de alimentos". Master, 2008. http://hdl.handle.net/10216/64173.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2019/07	The biochemical principles and applications of carbohydrate microarrays	XXVI Portuguese Chemical Society meeting 2019 (Porto, Portugal)
2017	Glycan microarrays in biological and medical research.	12th Meeting of the Portuguese Carbohydrate Group (Glupor 12) Portuguese Carbohydrate Group (Aveiro, Portugal)
2016/06/03	Neoglycolipid-based carbohydrate microarray technology: principles and applications	Universidade de Aveiro (Aveiro, Portugal)
2015	Insights into Helicobacter pylori lipopolysaccharide structural domains using a pathogen carbohydrate microarray.	11th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 11 – and 6th Iberian Carbohydrate Meeting (Viseu, Portugal)
2014	Probing structural domains of H. pylori lipopolysaccharides with glycan binding proteins using microarrays.	Glyco-T 2014, 9th International Symposium on Glycosyltransferases (Porto, Portugal)
2014	Helicobacter pylori cell-surface glycans: Isolation and structural characterization towards development of a novel pathogen microarray.	Glyco-T 2014, 9th International Symposium on Glycosyltransferases. (Porto)
2013	Helicobacter pylori cell surface glycans: Isolation and structural characterization towards development of a novel pathogen microarray.	REQUIMTE research group of Chemistry Department of FCT-UNL, Lisbon
2013	Helicobacter pylori cell-surface glycans: Isolation and structural characterization towards development of a novel pathogen microarray.	GLUPOR 10 and 1st Workshop of Carbohydrates (Covilhã, Portugal)
2013	GC-MS as a tool towards identification of typical sugars occurred in Helicobacter pylori lipopolysaccharides.	8º Encontro Nacional de Cromatografia (Covilhã, Portugal)
2013	Evaluation of the stress-induced growth of the Portuguese clinical isolate Helicobacter pylori CI-5 strain - a structural characterization of cell-surface lipopolysaccharides.	MicroBiotec 13 (Aveiro, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2023/10/01 - 2024/07/22	Exploração de fontes alternativas de proteína: extração e caracterização para aplicações alimentares nutricionais sustentáveis Co-supervisor of Rita Loureiro Carneiro	Bioquímica (Degree) Universidade do Porto Faculdade de Ciências, Portugal
2020/09 - 2021/12/06	Interaction study between carob galactomannans and proteins using carbohydrate microarray technology Supervisor	Biochemistry (Master) Universidade de Aveiro, Portugal
2021/02 - 2021/09/17	Água da demolha: o subproduto das leguminosas. Co-supervisor	Biochemistry (Degree) Universidade de Aveiro, Portugal
2021/02 - 2021/07/23	Improving aquafaba production: The effect of sodium bicarbonate. Co-supervisor	Biotechnology (Degree) Universidade de Aveiro, Portugal
2020/02 - 2020/07	Aquafaba - uma alternativa vegan às claras do ovo: estudo das propriedades físico-químicas visando a formulação e desenvolvimento de novos produtos. Supervisor	Biochemistry (Degree) Universidade de Aveiro, Portugal
2020/02 - 2020/07	Microcápsulas de levedura para aplicações biomédicas. Co-supervisor	Biochemistry (Degree) Universidade de Aveiro, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2024/10/16 - 2024/10/16	World Food Day 2024 – At FCUP and at Ribadouro College high school, Portugal. Theoretical and practical demonstration of ongoing projects in the Foodphenolab, regarding new products developments based on plant-based ingredients. A demonstration of insects as an alternative protein source was also included. (2024/10/16 - 2024/10/16) Exhibition (Member of the Organising Committee)	Universidade do Porto Faculdade de Ciências, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2024/07/08 - 2024/07/12	School of Chemistry and Biochemistry event, FCUP, Portugal. Training of a high school volunteer student regarding the interaction studies between polyphenols from beverages and the oral cavity components. Workshop	School of Chemistry and Biochemistry Universidade do Porto Faculdade de Ciências, Portugal
2019/10/10 - 2019/10/12	Demonstration of galactomannan-based microparticles for insulin pulmonary delivery Exhibition	TechDays 2019 Universidade de Aveiro, Portugal
2019/09/27 - 2019/09/27	Demonstration of pulmonary insulin delivery using polysaccharide-based carriers. Exhibition	European Researchers’ Night Universidade de Aveiro, Portugal
2018 - 2018	Glycosciences Laboratory (UK)_ Demonstration on how viruses seek out their sugar chain code. "Sugar maker" interactive activities with the public. Festival	White City Mash Up Imperial College London, United Kingdom
2017 - 2017	Glycosciences Laboratory (UK)_Demonstration entitled "Microchips to tell how viruses seek out their sugar chain code" and consisting of: poster, microarray slides demonstration and interactive activities with the public (age 3+) such as "Sugar maker": build "sugar receptors" of different viruses using foam stickers of different shapes and colours; 2018's update of the "Sugar maker" activity: production of sugar chains bracelets, necklaces or keyrings made out of beads to take home. Festival	Imperial College Festival Imperial College London, United Kingdom
2013 - 2013	Helicobacter pylori polysaccharides: occurrence and structural features. Workshop	2nd Workshop in Mass Spectrometry and Carbohydrates Universidade de Aveiro, Portugal

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2024/07/19 - 2024/07/26	Process-induced molecular level protein-carbohydrate-poly-phenol interactions in milk-tea blends: A review (foods-3135001)	Foods
2024/03/01 - 2024/03/11	Urinalysis reveals glycosaminoglycans as a potential biomarker for cardiovascular Staphylococcus aureus infection (HELIYON-D-24-06666)	Heliyon
2021/05/25 - 2021/06/07	Development of high throughput protocols for carbohydrate analysis in Lignocellulosic biomass (CARBPOL-D-21-02100)	Carbohydrate Polymers
2020/11/18 - 2020/12/09	Therapeutic effect of Zuojin Pill on chronic atrophic gastritis induced by Helicobacter pylori through JMJD2B/COX-2/VEGF (NPHB-2020-0731)	Pharmaceutical Biology
2018/04/04 - 2018/04/13	Exploring sialyl-Tn expression in microfluidic-isolated circulating tumour cells: a novel biomarker for precision oncology applications (MOLONC-18-0170)	Molecular Oncology

Committee member

	Activity description Role	Institution / Organization
2021 - 2023	Member of Thesis Advisory Committee of the PhD student Viviana G. Correia. Advisor / Consultant

Consulting

	Activity description	Institution / Organization
2019/04 - Current	Providing consultancy advice to the Glycosciences Lab regarding microarray equipment and training to the new staff members, assisting them with glycan microarray experiments and protein binding data analysis.	Imperial College London - Hammersmith Campus, United Kingdom
2018 - Current	Peer-reviewing in international journals: Carbohydrate Polymers, Molecular Oncology, Pharmaceutical Biology, Foods and Heliyon.

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2021/03 - 2021/07	Practical modules of the Curricular Unit of General Chemistry	(Licenciatura)	Universidade de Aveiro, Portugal
2021/05/13 - 2021/05/14	Training course on Glycan Microarrays: practical aspects of neoglycolipid (NGL)-based microarrays. Glycosciences Laboratory, Imperial College London
2018/12/11 - 2018/12/11	Invited lecture on Glycobiology (MODULE 4: IMMUNE REGULATION) as part of MSc Immunology Course	(Master)	Imperial College London - Hammersmith Campus, United Kingdom
2017/12/12 - 2017/12/12	Invited lecture on Glycobiology (MODULE 4: IMMUNE REGULATION) as part of MSc Immunology Course	(Master)	Imperial College London - Hammersmith Campus, United Kingdom
2015/12/11 - 2015/12/11	Invited lecture on Glycobiology (MODULE 4: IMMUNE REGULATION) as part of MSc Immunology Course	(Master)	Imperial College London - Hammersmith Campus, United Kingdom

Distinctions

Award

2015	Travel award ($500) Society for Glycobiology, United States
2010	4-year post-graduate PhD research fellowship funded by FCT (SFRH/BD/71455/2010) Fundação para a Ciência e a Tecnologia, Portugal