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Liane Moura obtained her Ph.D. in Biotechnology in 2013 (University of Coimbra). Liane is a member of the BioNanoSciences group at iMed.ULisboa. From 2014-2019, Liane was a Post-Doctoral fellow and used a rational approach to design multifunctional poly (glutamic acid)-dendrimers to target dendritic cells and co-deliver antigens and adjuvants for the activation of APC. Since 2019, Liane is a Junior Researcher in the Faculty of Pharmacy, University of Lisbon. Understanding the complexity of tumor microenvironment (TME) and how tumor-stromal-microbiota-neuro-immune cell interplay impacts the efficacy of cancer nanovaccines are major research interests of Liane. In parallel, Liane is working on the development of polypeptide-based nanocarriers as immunotherapeutic approaches, able to conjugate and deliver different active biomolecules to immune and cancer cells, for cancer treatment. Liane has developed nano-engineered vaccines to modulate of the tumor-associated microbiota and TME immune profiling for different cancers. Liane is the PI of a project “Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer”. Recently, Liane is interested in deepening the impact of tumor-associated nerves in tumor progression. Liane has been a core member within the team of other cancer nanoimmune-related research projects ongoing in the lab. Since 2018, Liane is involved in the support of practical classes teaching in the FFUL, having a postgraduate course in Pedagogy in Higher Education. Since 2023, Liane is a Guest Editor of Pharmaceutics Journal. Liane is the first author of 1 invited book chapter and 9 peer-reviewed international papers (plus 1 under revision) and co-author of the other 12 (plus 1 under revision; 2 submitted). She has 1627 citations and an h-index of 17 (by Scopus). The list includes top specialty journals (Nature Nanotechnology, Advanced Science, Seminars in Immunology). Liane has 19 communication abstracts published in international journals with impact factor, 28 selected oral communications, and 67 presentations as poster (2 as corresponding author). Liane has developed various collaborations and participated actively in laboratory management. She was awarded 12 grants from renowed scientific societies. She was involved in the organization of scientific meetings for the dissemination of science and she is a member of various national/international scientific societies. Liane is an external reviewer of Cost Action proposals and various scientific journals. Liane has participated in diverse national and international funded projects (as Co-PI and team member). She supervises various undergraduate students (2 ongoing; 9 finished), master students (4 finished) as well as ERASMUS students (2 ongoing; 3 finished). Liane also participated as Jury member in Master Thesis.
Read full resume ↓
Identification

Personal identification

Full name
Liane Moura
Date of birth
1986/04/01
Gender
Female

Citation names

  • Moura, Liane I F

Author identifiers

Ciência ID
8110-8802-8E65
ORCID iD
0000-0003-4264-6865
Google Scholar ID
https://scholar.google.pt/citations?hl=ptBR&user=iZwCbtwAAAAJ
Researcher Id
F-6534-2015
Scopus Author Id
37661789300

Email addresses

  • lmoura@ff.ulisboa.pt (Professional)
  • moura.liane@gmail.com (Personal)

Telephones

Telephone
  • 217946400 (Professional)

Addresses

  • iMed.ULisboa. Avenida Professor Gama Pinto, 1649-003, Lisboa – Portugal, Lisboa, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Advanced (C1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Portuguese (Mother tongue)
Education
Degree Classification
2021/10 - 2022/07/30
Concluded
 Pedagogy for the Higher Education (Pós-Graduação)
Universidade de Lisboa Instituto da Educação, Portugal
 Approved
2009/10/01 - 2013/11/05
Concluded
 Engenharia Química - Biotecnologia (Doutoramento)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Development of novel therapeutic approaches for wound healing in diabetes" (THESIS/DISSERTATION)
 Summa cum laude
2004 - 2008
Concluded
 Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Effects of natural polyphenols in angiogenesis and inflammation" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2019/03/01 - Current Auxiliary Researcher (Research) Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/12/01 - 2019/02/28 Postdoc (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/10/01 - 2016/12/30 Visiting Researcher (Research) Biomaterials Biodegradables and Biomimetics, Portugal
Universidade do Minho, Portugal
2015/07/01 - 2016/06/30 Visiting Researcher (Research) University of Hertfordshire Department of Pharmacy, United Kingdom

Teaching in Higher Education

Category
Host institution 		Employer
2018/02/01 - Current Trainee Assistant (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
2023 - Current Guest Editor Pharmaceutics Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - Current Laboratory Management Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/10 - 2023/05 Maternity Leave Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/10/01 - 2020/04/26 Maternity Leave Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - 2013 Laboratory Management Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/04/01 - 2009/09/30 Graduate Research fellow Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/02/01 - 2008/10/31 Undergraduated training Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2022 - 2025 Multifunctional nano-immunotherapy for melanoma brain metastases treatment
PTDC/BTM-SAL/4350/2021
member of the Research Team
Fundação para a Ciência e a Tecnologia
Ongoing
2022/09/01 - 2024/03/31 Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer
Exploratory Research Projects - 2022.04506.PTDC
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 Next-generation nanomaterials to sensitize breast cancer to immunotherapy
UTAP-EXPL/NPN/0041/2021
Other
The University of Texas at Austin College of Pharmacy, United States
 Fundação para a Ciência e a Tecnologia
Concluded
2020 - 2023 Instituto de Investigação do Medicamento
UIDP/04138/2020
Other
Ongoing
2019/11 - 2020/11 HybExo-ALS - Engineering hybrid exosomes as microRNAs nanocarriers to microglia in Amyotrophic Lateral Sclerosis
100021-UID/DTP/04138/2019
Principal investigator
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Universidade de Lisboa Instituto de Investigação do Medicamento
Concluded
2013 - 2013 Promoting endothelial progenitor cell function in diabetic wound healing
EFSD/JDRF
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Foundation for the Study of Diabetes
Concluded

Contract

Designation Funders
2018 - Current MultiNano@MBM: Modulation of melanoma-stroma interactions using a rationally-designed nanomedicine combining BRAFi-, MEKi- and immune-therapies
ENMed/0051/2016
Post-doc
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018 - Current POLYMMUNE: Off-the-Shelf Polypeptide-based Immunotherapy for Advanced Melanoma Treatment
ERC-POC: SEP-210512889
Post-doc
Centro de Investigacion Principe Felipe, Spain
 European Research Council
Concluded
2018 - Current Boronated Cytotoxic Multivalent Platforms - A New Concept to Fight Cancer
PTDC/QUI-QOR/29967/2017
Post-doc
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2023/03/12 - 2024/09/11 Nano-imunoterapia para regular o perfil imunológico e o microbioma no cancro pancreático
2022.04506.PTDC
10.54499/2022.04506.PTDC
Fundación de la Comunidad Valenciana Centro de Investigación Príncipe Felipe, Spain

Universidade NOVA de Lisboa NOVA Medical School, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020 - 2021 Nanomateriais para desenho de novas vacinas
UTA-EXPL/NPN/0082/2019
10.54499/UTA-EXPL/NPN/0082/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Research Institute for Medicines
UID/DTP/04138/2019
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Instituto Politécnico de Coimbra Centro de Estudos de Recursos Naturais Ambiente e Sociedade, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015 - 2018 Multidisciplinary Strategy to Develop Novel Multicomponent Nanoscale Systems for Immune Modulation.
UTAP-ICDT/DTP-FTO/0016/2014
Post-doc
Fundação para a Ciência e a Tecnologia
Concluded
2012/10/01 - 2014/11/30 Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level
info:eu-repo/grantAgreement/EC/FP7/316331/EU
Post-doc Fellow
Biomaterials Biodegradables and Biomimetics, Portugal
 European Commission
Concluded
2013/06/01 - 2013/11 Anticipating diabetes and diabetic wounding for siblings of Type 2 diabetics.
EXCL/DTP-PIC/0069/2012
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
2013/01/01 - 2013 MECHANISMS AND TREATMENT STRATEGIES OF IMPAIRED WOUND HEALING IN DIABETES
EXPL/BIM-MED/0492/2012
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012 - 2013 Neuropeptide release in wounds: a new therapeutic approach for the treatment of diabetic foot ulceration
PTDC/SAU-FAR/121109/2010
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009 - 2012 Dissecting the molecular mechanisms of wound healing in diabetes - the role of neuropeptides
PTDC/SAU-MII/098567/2008
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Moura, Liane I F; Silva, Ana Luísa; Carreira, Barbara; Conniot, J; Matos, AI; Peres, C; Sainz, V.; et al. "Functional moieties for intracellular traffic of nanomaterials.". In Biomedical Applications of Functionalized Nanomaterials. Elsevier, 2018.
    Accepted
Conference abstract
  1. Carreira, Bárbara; Acúrcio, Rita C; Pozzi, Sabina; Ron Kleiner; Moura, Liane I F; Ana I. Matos; Daniella Vaskovich-Koubi; et al. Corresponding author: Ronit Satchi. "Abstract 835: Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Paper presented in AACR Annual Meeting 2023, Orlando, 2023.
    Published • 10.1158/1538-7445.AM2023-835
Conference paper
  1. Carreira B; Acúrcio R; Pozzi S; Moura, Liane I F; Vaskovich D; Peres C; Fernandes A; et al. "Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Paper presented in Proceedings of the American Association for Cancer Research Annual Meeting 2023, 2023.
    10.1158/1538-7445.AM2023-835
  2. C Peres; AI Matos; Moura, Liane I F; B Carreira; M Verdial; J Conniot; MB Afonso; et al. Corresponding author: H Florindo. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". Paper presented in 46th FEBS Congress, 2022.
    Published • -
  3. Moura, LIF; Duro-Castano A; Peres C; Gallon E; Sainz V; Vicent MJ; Florindo H. "A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Paper presented in 25th Biennial Congress of the European Association for Cancer Research, 2018.
  4. Moura, L; Duro-Castano, A; Peres, C; Gallon, E; Matos, A; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". 2018.
    10.1136/esmoopen-2018-eacr25.927
  5. Moura, Liane I F; Martinho, N; Florindo, H; Zloh, M.. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy-a computational design approach". Paper presented in 42nd FEBS Congress, 2017, Jerusalem, 2017.
    Published
  6. Leal, EC; Pirzgalska, R; Marques da Silva, D; Moura, Liane I F; Espinoza, D; Ledent C; Koffalvi A; Carvalho, E.. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". Paper presented in 53rd EASD Annual Meeting, 2017.
    Published
  7. Moura, Liane I F. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". 2017.
  8. Moura, Liane I F; Martinho, N; Florindo, H; Zloh, M. "Computational design of a novel poly-glutamic dendrimer-based platform as an anticancer therapeutic approach". Paper presented in 41st FEBS Congress, 2016.
  9. Leal, EC; Pirzgalska, R; Marques da Silva, D; Moura, LIF; Espinoza, D; Ledent C; Koffalvi A; Carvalho, E.. "Diabetes Decreases CB1 Cannabinoid Receptor Expression Promoting Early Skin Aging". Paper presented in 75th Scientific Sessions of the American Diabetes Association, 2015.
  10. Carvalho, Lina; Moura, Liane I F; Ferreira Teresa; Aguiar MJ; Dinis A; Dias, Ana M. A.; Suesca, Edward; et al. "Collagen-based dressings loaded with neurotensin repair ulcers in diabetic mice". Paper presented in 24th European Congress of Pathology, 2013.
  11. Moura, Liane I F; Dias, AM; Suesca, E; Casadiegos, S.; Duque, MF; de Sousa, H.C.; Carvalho, Eugénia. "Neurotensin and collagen dressings improve diabetic wound healing". Paper presented in Annual Meeting of Portuguese Society of Diabetology, 2013, 2013.
  12. Pirgsgalska, R; Moura, Liane I F; Espinoza, D; Koffalvi, A; Leal, EC; Carvalho, Eugénia. "CB1 cannabinoid receptor can contribute to early skin aging in diabetes". Paper presented in Anual Meeting of Portuguese Society of Diabetology, 2013, 2013.
  13. Moura, Liane I F; Dias, AM; Suesca, E.; Casadiegos, S.; Duque MF; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Paper presented in 48th EASD Annual Meeting, 2012.
  14. Carvalho, Lina; Moura, Liane I F; Dias, Ana M.A.; de Sousa, H.C.; Carvalho, Eugénia. "Neurotensin and Chitosan-based dressings repair ulcers of diabetic mice". Paper presented in European Conference of Pathology, 2012.
  15. Moura, Liane I F; Morgado, C; Pedro, JR; Lemos, C; Carvalho, Eugénia; Kofalvi, A. "Streptozotocin-induced type-1 diabetes triggers deregulation of cerebral glucose metabolism identical to genetic deletion of the CB1 cannabinoid receptor". Paper presented in 8th FENS Forum of Neuroscience 2012, 2012.
  16. Moura, Liane I F; Dias, AM; Leal, EC; de Sousa, HC; Carvalho, Eugénia. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Paper presented in 10º Congresso Português de Diabetes, 2012, 2012.
  17. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells in a fibrin gel". 2011.
  18. Moura, Liane I F; Dias, AM; Leal, EC; de Sousa, H.C.; Carvalho, E.. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Paper presented in 47th EASD Annual Meeting, 2011, 2011.
  19. Leal, EC; Tellechea, A; Moura, Liane I F; Veves, A; Carvalho, E. "The role of neurotensin in wound healing in diabetic and iNOS knockout mice". Paper presented in 70th Scientific Sessions of the American Diabetes Association, 2010.
Conference poster
  1. Ana I. Matos; Carina Peres; Bárbara Carreira; Moura, Liane I F; Rita C. Acúrcio; Ana S. Viana; Luís Graça; Ronit Satchi-Fainaro ; Helena F. Florindo. "Polyoxazoline Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and PD-1 blockade against Solid Tumors". Paper presented in XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  2. R.C. Acúrcio; I. C. Sanchez; Moura, Liane I F; M. J. Vicent; R. Satchi-Fainaro ; H.F. Florindo. "From cold to hot: Nanotechnology-based immunotherapy driving effective PDAC anti-tumor response". Paper presented in XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  3. Jéssica Cordeiro; Immaculada Conejos-Sánchez; Ana I Matos; Moura, Liane I F; María J. Vicent; Helena Florindo. Corresponding author: Moura, Liane I F. "Combined nano-immunotherapy to regulate immune profiling and tumor-associated stroma in breast cancer". Paper presented in XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  4. Silva M; Carreira B; Acúrcio R; Bonomo A; Matos AI; Moura LIF; Florindo HF. "Nano-immunotherapy for melanoma – a window of translation oncology". Paper presented in III ASPIC-ASEICA International Meeting, 2023.
  5. Cordeiro, Jéssica; CONEJOS-SANCHEZ, INMACULADA; Acúrcio, Rita C; Moura, Liane I F; María J. Vicente; Helena F Florindo. Corresponding author: Moura, Liane I F. "Nano-immunotherapy to modulate immune cells in pancreatic cancer". Paper presented in "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas¿, 2023.
  6. Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Moura, Liane I F; Ana I. Matos; Kleiner, Ron; Vaskovich-Koubi, Daniella; et al. Corresponding author: Helena F Florindo. "Translational nanotechnology-based cancer nanovaccine to re-educate host immune response against melanoma brain metastases". Paper presented in Gordon Research Conference on Cancer Nanotechnology and Gordon Research Seminar on Cancer Nanotechnology, 2023.
  7. Carreira, Bárbara; Rita Acúrcio; Sabina Pozzi; Moura, Liane I F; Peres, Carina; Fernandes, Adelaide; Xapelli Sara; Satchi-Fainaro, Ronit; Helena F Florindo. "Precision Nanomedicine-based Immunotherapy to Overcome Immunosuppression Against Metastatic Melanoma.". Paper presented in Champalimaud Research Symposium: Tumor Microenvironment (from cancer initiation to metastasis), 2022.
  8. Bento M; Mendes N; Moura, Liane I F; Wegener E; Jordan R, ; Conejos-Sánchez I; Vicent MJ,; Satchi-Fainaro R; Florindo HF. Corresponding author: Florindo HF. "Multifunctional Nano-therapy to Overcome Pancreatic Cancer Immune Evasion". Paper presented in 13th iMed.ULisboa – Postgraduate Students Meeting, 2022.
  9. Peres C; Matos A; Moura, Liane I F; Carreira B; Graça L; Préat V; Satchi-Fainaro R; Florindo HF. "Targeted nanovaccine as a powerfull platform to improve immune modulation and checkpoint therapies in colorectal cancer". Paper presented in 28th Congress of the European Association for Cancer Research, 2022.
  10. Matos A; Peres C; Moura, Liane I F; Carreira B; Viana AS; Graça L; Satchi-Fainaro R; Florindo HF. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". Paper presented in 28th Congress of the European Association for Cancer Research, 2022.
  11. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, A. S.; Graca, Luis; Satchi-Fainaro, Ronit; Helena F Florindo. "Targeted nanovaccine as a powerful platform to improve immune modulation and checkpoint therapies in colorectal cancer". Paper presented in EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  12. Moura, LIF; Manfanti A; Vicent MJ; Florindo H. "Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy". Paper presented in 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice, 2022.
  13. Bento M; Moura, Liane I F; Florindo HF. "Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion". Paper presented in 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice, 2022.
  14. Moura, Liane I F; Florindo H. "Student centered teaching towards critical thinking in pharmaceutical technology". Paper presented in Jornadas Pedagógicas da Universidade de Lisboa - Ensino 4.0: Transição Digital, 2022.
  15. "Multivalent branched polypeptide-based nanovaccine as a novel immunotherapeutic approach for melanoma". Paper presented in LPCC_Cutaneous Melanoma: From Where to Where?, 2021.
    -
  16. "Precision Nanomedicine-based therapeutics to regulate immunosuppression against metastatic melanoma". Paper presented in Virtual iMed.ULisboa Meeting 2021, 2021.
    -
  17. "Multifunctional nanovaccine synergizes with OX-40 agonist in triple-negative breast cancer". Paper presented in EACR2021, 2021.
    -
  18. Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Moura, Liane I F; Ana I. Matos; Satchi-Fainaro, Ronit; Helena F Florindo. Corresponding author: Helena F Florindo. "Precision Multifunctional Nanomedicines to Regulate Immunosuppression Against Melanoma Brain Metastasis". Paper presented in Cutaneous Melanoma: From Where to Where?,, 2021.
  19. Ana I. Matos; Pena, Sandra; Mateus, Mariana; Carreira, Bárbara; Peres, Carina; Moura, Liane I F; Viana, Ana S. or Viana, Ana; et al. "Targeted nanovaccine as a powerful platform to improve immune modulation therapy in colorectal cancer". Paper presented in EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
  20. "Multifunctional nanovaccine synergizes with immune checkpoint therapy against triple-negative breast cancer". Paper presented in EACR-AACR Basic and Translational Research Conference in partnership with ASPIC Tumor Microenvironment, 2020.
    -
  21. "Targeted nanovaccine as a powerfull platform to improve immune modulation therapy in colorectal cancer". Paper presented in EACR-AACR Basic and Translational Research Conference in partnership with ASPIC Tumor Microenvironment, 2020.
    -
  22. "Functionalized nanobiomaterials as novel combination immunotherapies in cancer.". Paper presented in EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
    -
  23. Moura, Liane I F; Duro-Castano A; Malfanti A; Peres, C; Gallon E; Matos, AI; Benito AA; Vicent, MJ; Florindo, HF. "Multivalent polypeptide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma". Paper presented in 17th Annual Meeting of the Association for Cancer Immunotherapy - CIMT, 2019.
  24. Aguiam N; Moura, Liane I F; Florindo, HF; Lopes JA. "Nanotechnology in medicine and challenges for the manufacturing of nanomedicines.". Paper presented in 14th Meeting of the Spanish Society of Pharmaceutics and Pharmaceutical Technology, 2019.
  25. Matos, AI; Carreira, Barbara; Moura, Liane I F; Peres, Carina; Viana, AS; Conde, JP; Graca, Luis; Satchi-Fainaro, Ronit; Helena F Florindo. Corresponding author: Helena F Florindo. "Targeted nanovaccine as a powerfull platform to treat colorectal cancer.". Paper presented in EACR-AACR-ASPIC Conference: Nanotechnology in Cancer: Engineering for Oncology,, 2019.
  26. Moura, L; Duro-Castano, A; Peres, C; Gallon, E; Matos, A; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Paper presented in 25th Biennial Congress of the European Association for Cancer Research., 2018.
    10.1136/esmoopen-2018-eacr25.927
  27. Peres, C; Matos, AI; Moura, Liane I F; Conniot, João; Carreira, Bárbara; Préat, V.; Satchi-Fainaro, R.; Florindo, H.F.; Graça, L. "Nanoparticle- based vaccine improved OX40 anti-tumor efficacy in breast cancer". Paper presented in 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018.
  28. Peres, Carina; Ana I. Matos; Moura, Liane I F; Conniot, João; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; et al. "Nanoparticle-based vaccine improved the anti-tumor efficacy of the immune checkpoint co-stimulator OX40 in breast carcinoma". Paper presented in 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018.
  29. Florindo, H.F.; Peres, C; Conniot, J.; Moura, Liane I F; Matos, AI; Satchi-Fainaro, R.. "Polymeric nano-vaccines improved OX40 anti-tumor efficacy against breast cancer". Paper presented in Controlled Release Society Annual Meeting and Exposition., 2018.
  30. Moura, Liane I F; Duro-Castano, A; Peres, Carina; Gallon, Elena; Sainz, Vanessa; Ana I. Matos; Vicent, María J.; Helena F Florindo. "A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Paper presented in Frontiers in Immunomodulation and Cancer Therapy, 2018.
  31. Matos, AI; Peres, C; Moura, L; Carreira, B; Viana, AS; Graça, L; Gaspar, R; Conde, JP; Florindo, HF. "PO-415 Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". Paper presented in 25th Biennial Congress of the European Association for Cancer Research, 2018.
    10.1136/esmoopen-2018-eacr25.926
  32. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; Gaspar, Rogerio S; Conde, J.P.; Helena Florindo. "Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". Paper presented in EACR25: From Fundamental Insight to Rational Cancer Treatment, 2018.
  33. Moura, Liane I F; Duro-Castano, A; Vicent, MJ; Florindo, HF. "A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma.". Paper presented in 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, 2018.
  34. Matos, AI; Moura, Liane I F; Conde, JP; Florindo, HF. "Multivalent polymeric nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation.". Paper presented in 16th CIMT Annual Meeting – Pushing Frontiers in Cancer Immunotherapy, 2018.
  35. Matos, AI; Peres, C; Moura, Liane I F; Conde, JP; Florindo, HF. "PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation.". Paper presented in 3rd ASPIC International Congress, 2018.
  36. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; Gaspar, Rogério; Conde, J.P.; Helena Florindo. "Multivalent PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation". Paper presented in 3rd ASPIC International Congress, 2018.
  37. Moura, Liane I F; Duro-Castano, A; Peres, C; Vicent, MJ; Florindo, H. F.. "Multifunctional polypeptide-based platform as an anti-cancer immunotherapeutic approach for melanoma.". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  38. Moura, Liane I F; Duro-Castano, A; Peres, C; Gallon E; Vicent, MJ; Florindo, HF. "A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma". Paper presented in Frontiers in Immunomodulation and Cancer Therapy, 2018.
  39. Moura, Liane I F; Martinho, N; Florindo, HF; Zloh, M. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy – a computational design approach". Paper presented in 42nd FEBS Conference, 2017.
  40. Peres, Carina; Moura, Liane I F; Ana I. Matos; Sainz, Vanessa; Viana, Ana S. or Viana, Ana; Gaspar, Rogério; Graca, Luis; Préat, Véronique; Helena F Florindo. "Polymeric nanoparticles as cancer vaccines and immunomodulators". Paper presented in 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, 2017.
  41. Sainz, Vanessa; Peres, Carina; Moura, Liane I F; Ana I. Matos; Viana, Ana S. or Viana, Ana; Lopes, João; Gaspar, Maria Manuela; et al. "Hybrid Lipid-Polymeric Nanoparticles for the Treatment of Melanoma by Strengthening the Host Immune Response". Paper presented in 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, 2017.
  42. Moura, Liane I F; Duro-Castano, A; Vicent, MJ. "A novel multifunctional star-shaped polypeptide-based platform as an anti-cancer immunotherapeutic approach". Paper presented in Gordon Research Conference “Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer”, 2017.
  43. Peres, Carina; Moura, Liane I F; Ana I. Matos; Sainz, Vanessa; Viana, Ana S. or Viana, Ana; Gaspar, Rogério; Graca, Luis; Préat, Véronique; Helena F Florindo. "Polymeric nanoparticles as breast cancer vaccines and immunomodulators". Paper presented in GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer, 2017.
  44. Sainz, V.; Peres, C; Moura, Liane I F; Zloh, M; Florindo, HF. "A novel nanoplatform as metastatic melanoma cancer vaccine". Paper presented in 1st SPLC-CRS Young Scientist Meeting, 2017.
  45. Helena F Florindo; Zupancic, Eva; Peres, Carina; Sainz, Vanessa; Ana I. Matos; Moura, Liane I F; Curato, Caterina; et al. "Multicomponent Nanoscale Systems for Immune Modulation Against Solid Tumors.". Paper presented in Frontiers in Cancer Immunotherapy, 2017.
  46. Peres, Carina; Sainz, Vanessa; Ana I. Matos; Viana, Ana S. or Viana, Ana; Moura, Liane I F; Graca, Luis; Préat, Véronique; Helena F Florindo. "Multicomponent aliphatic polyester-based nanoparticles for antigen delivery and immune modulation against cancer disease". Paper presented in NanoBio&Med2016, 2016.
  47. Moura, Liane I F; Martinho, N; Florindo, H.F.; Zloh, M. "Computational design of a novel poly–glutamic dendrimer-based platform as an anticancer therapeutic approach". Paper presented in 41th FEBS Congress, 2016.
  48. Sainz, V.; Moura, Liane I F; Florindo HF. "Multicomponent nanoscale systems as metastatic melanoma therapeutic cancer vaccines". Paper presented in UT Austin|Portugal Annual Conference, 2016.
  49. Moura, Liane I F; Aroso, I; Reis, RL; Pires, RA. "Cork extracts induce a cytoprotective effect against H2O2 oxidative damage in SH--SY5Y cells". Paper presented in IV ICVS/3B´S Meeting, 2014.
  50. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Paper presented in Annual Meeting of Portuguese Society of Diabetology, 2013.
  51. Pirsgalska, R; Moura, Liane I F; Espinoza, D; Leal, EC; Carvalho, E. "CB1 cannabinoid receptor can contribute to early skin aging in diabetes". Paper presented in CISE 2012 Conference, 2012.
  52. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Paper presented in 8th EASD Annual Meeting, 2012.
  53. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Paper presented in 47th EASD Annual Meeting, 2011.
  54. Moura, Liane I F; Soares Raquel; Negrão, Rita. "Effects of natural polyphenols on angiogenesis and inflammation". Paper presented in XVI National Congress of Biochemistry, 2008.
Journal article
  1. Matos, Ana I. I.; Peres, Carina; Carreira, Barbara; Moura, Liane I. F.; Acurcio, Rita C. C.; Vogel, Theresa; Wegener, Erik; et al. "Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors". Advanced Science (2023): https://publons.com/wos-op/publon/55939439/.
    10.1002/ADVS.202300299
  2. Peres, C.; Matos, A. I.; Moura, L. I. F.; Carreira, B.; Verdial, M.; Conniot, J.; Afonso, M. B.; et al. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". FEBS Open Bio (2022): https://publons.com/wos-op/publon/53912188/.
  3. C. Leal, Ermelindo; F. Moura, Liane I.; Pirzgalska, Roksana M.; Marques-da-Silva, Dorinda; Ledent, Catherine; Köfalvi, Attila; Carvalho, Eugenia. "Diabetes and Cannabinoid CB1 receptor deficiency promote similar early onset aging-like changes in the skin". Experimental Gerontology 154 (2021): 111528. http://dx.doi.org/10.1016/j.exger.2021.111528.
    10.1016/j.exger.2021.111528
  4. Peres, Carina; Matos, Ana I.; Moura, Liane I.F.; Acúrcio, Rita C.; Carreira, Barbara; Pozzi, Sabina; Vaskovich-Koubi, Daniella; et al. "Preclinical models and technologies to advance nanovaccine development". Advanced Drug Delivery Reviews 172 (2021): 148-182. http://dx.doi.org/10.1016/j.addr.2021.03.001.
    10.1016/j.addr.2021.03.001
  5. Pedro, Joana Reis; Moura, Liane I.F.; Valério-Fernandes, Ângela; Baptista, Filipa I.; Gaspar, Joana M.; Pinheiro, Bárbara S.; Lemos, Cristina; et al. "Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes". Brain Research Bulletin 161 (2020): 106-115. http://dx.doi.org/10.1016/j.brainresbull.2020.05.004.
    10.1016/j.brainresbull.2020.05.004
  6. Conniot, João; Scomparin, Anna; Peres, Carina; Yeini, Eilam; Pozzi, Sabina; Matos, Ana I.; Kleiner, Ron; et al. "Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators". Nature Nanotechnology 14 9 (2019): 891-901. http://dx.doi.org/10.1038/s41565-019-0512-0.
    10.1038/s41565-019-0512-0
  7. Matos, Ana I.; Carreira, Barbara; Peres, Carina; Moura, Liane I.F.; Conniot, João; Fourniols, Thibaut; Scomparin, Anna; et al. "Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer". Journal of Controlled Release 307 (2019): 108-138. http://dx.doi.org/10.1016/j.jconrel.2019.06.017.
    10.1016/j.jconrel.2019.06.017
  8. Liane I.F. Moura; Cristina Lemos; Catherine Ledent; Eugénia Carvalho; Attila Köfalvi. "Chronic insulinopenia/hyperglycemia decreases cannabinoid CB1 receptor density and impairs glucose uptake in the mouse forebrain". Brain Research Bulletin 147 (2019): 101-109. https://doi.org/10.1016/j.brainresbull.2019.01.024.
    Published • 10.1016/j.brainresbull.2019.01.024
  9. Liane I. F. Moura; Alessio Malfanti; Carina Peres; Ana I. Matos; Elise Guegain; Vanessa Sainz; Mire Zloh; María J. Vicent; Helena F. Florindo. "Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders". Materials Horizons 6 10 (2019): 1956-1975. https://doi.org/10.1039/C9MH00628A.
    Published • 10.1039/C9MH00628A
  10. Moura, Liane I F; Sains, V; Peres, C; Matos, AI; Viana, AS; Wagner, AM; Ramirez, JV; et al. "a-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma". Acta Biomaterialia 76 (2018): 193-207.
    Published • 10.1016/j.actbio.2018.06.029
  11. Silva, Ana Luísa; Peres, Carina; Conniot, João; Matos, Ana I.; Moura, Liane; Carreira, Bárbara; Sainz, Vanessa; et al. "Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation". Seminars in Immunology 34 (2017): 3-24. http://dx.doi.org/10.1016/j.smim.2017.09.003.
    10.1016/j.smim.2017.09.003
  12. Moura, L. I. F.; Martinho, N.; Silva, L. C.; Barata, T. S.; Brocchini, S.; Florindo, H. F.; Zloh, M.; et al. "Poly-glutamic dendrimer-based conjugates for cancer vaccination – a computational design for targeted delivery of antigens". Journal of Drug Targeting 25 9-10 (2017): 873-880. http://dx.doi.org/10.1080/1061186x.2017.1363213.
    Published • 10.1080/1061186x.2017.1363213
  13. Moura, L.; Martinho, N.; Florindo, H.; Zloh, M.. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy - a computational design approach". The FEBS Journal (2017): https://publons.com/wos-op/publon/10909664/.
  14. Leal, E. C.; Pirzgalska, R.; Marques-da-Silva, D.; Moura, L.; Espinoza, D.; Ledent, C.; Kofalvi, A.; Carvalho, E.. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". Diabetologia (2017): https://publons.com/wos-op/publon/18569683/.
  15. Sainz, Vanessa; Conniot, João; Matos, Ana I.; Peres, Carina; Zupanoio, Eva; Moura, Liane; Silva, Liana C.; Florindo, Helena F.; Gaspar, Rogério S.. "Regulatory aspects on nanomedicines". Biochemical and Biophysical Research Communications 468 3 (2015): 504-510. http://dx.doi.org/10.1016/j.bbrc.2015.08.023.
    10.1016/j.bbrc.2015.08.023
  16. Moura, Liane I F; Dias, Ana M A; Suesca, Edward; Casadiegos, Sergio; Leal, Ermelindo C; Fontanilla, Marta R; Carvalho, Lina; et al. "Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic mice". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 1 (2014): 32-43. http://hdl.handle.net/10316/80404.
    10.1016/j.bbadis.2013.10.009
  17. Moura, L.I.; Cruz, M.T.; Carvalho, E.. "The effect of neurotensin in human keratinocytes - implication on impaired wound healing in diabetes". Experimental Biology and Medicine 239 1 (2014): 6-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891928865&partnerID=MN8TOARS.
    10.1177/1535370213510665
  18. Pereira da Silva, Lucília; Miguel Neves, Bruno; Moura, Liane; Cruz, Maria Teresa; Carvalho, Eugénia. "Neurotensin Decreases the Proinflammatory Status of Human Skin Fibroblasts and Increases Epidermal Growth Factor Expression". International Journal of Inflammation 2014 (2014): 1-9. http://dx.doi.org/10.1155/2014/248240.
    Published • 10.1155/2014/248240
  19. Moura, L.I.F.; Dias, A.M.A.; Leal, E.C.; Carvalho, L.; De Sousa, H.C.; Carvalho, E.. "Chitosan-based dressings loaded with neurotensin - An efficient strategy to improve early diabetic wound healing". Acta Biomaterialia 10 2 (2014): 843-857. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896548394&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.09.040
  20. Moura, Liane I F; Dias, Ana M A; Carvalho, Eugénia; de Sousa, Hermínio C; Moura, L.I.F.; Dias, A.M.A.; Carvalho, E.; De Sousa, H.C.. "Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review". Acta Biomaterialia 9 7 (2013): 7093-7114. http://hdl.handle.net/10316/80328.
    10.1016/j.actbio.2013.03.033
  21. Moura, Liane I. F.; Silva, Lucília; Leal, Ermelindo C.; Tellechea, Ana; Cruz, Maria Teresa; Carvalho, Eugénia. "Neurotensin Modulates the Migratory and Inflammatory Response of Macrophages under Hyperglycemic Conditions". BioMed Research International 2013 (2013): 1-13. http://dx.doi.org/10.1155/2013/941764.
    10.1155/2013/941764
  22. Carvalho, L.; Moura, L.; Ferreira, T.; d'Aguiar, M. J.; Dinis, A.; Suesca, E.; Casadiegas, S.; Fontanilla Duque, M.; de Sousa, H. C.. "Collagen-based dressings loaded with neurotensin repair ulcers in diabetic mice". Virchows Archiv (2013): https://publons.com/wos-op/publon/10403277/.
  23. Moura, L.; Dias, A.; Suesca, E.; Casadiegos, S.; Duque, M. F.; Sousa, H.; Carvalho, E.. "Neurotensin and collagen dressings improve diabetic wound healing". Diabetologia (2012): https://publons.com/wos-op/publon/5975838/.
  24. Carvalho, L.; Moura, L.; Dias, A.; Sousa, H.; Carvalho, E.. "Neurotensin and Chitosan-based dressings repair ulcers of diabetic mice". Virchows Archiv (2012): https://publons.com/wos-op/publon/10403276/.
  25. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells". PLoS ONE 6 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79551528768&partnerID=MN8TOARS.
    10.1371/journal.pone.0016114
  26. da Silva, L.; Moura, L.; Neves, B. M.; Cruz, M. T.; Carvalho, E.; Neves, B.M.; Cruz, M.T.. "Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression". Diabetologia 1813 10 (2011): 1863-1871. https://publons.com/wos-op/publon/10403304/.
    10.1016/j.bbamcr.2011.06.018
  27. Moura, L.; Dias, A.; Leal, E.; Sousa, H.; Carvalho, E.. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Diabetologia (2011): https://publons.com/wos-op/publon/5975822/.
  28. Negrão, R.; Costa, R.; Duarte, D.; Taveira Gomes, T.; Mendanha, M.; Moura, L.; Vasques, L.; Azevedo, I.; Soares, R.. "Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells". Journal of Cellular Biochemistry 111 5 (2010): 1270-1279. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649890064&partnerID=MN8TOARS.
    10.1002/jcb.22850
  29. Leal, Ermelindo; Tellechea, Ana; Moura, Liane; Veves, Aristidis; Carvalho, Eugenia. "The Role of Neurotensin in Wound Healing in Diabetic and iNOS Knockout Mice". Diabetes (2010): https://publons.com/wos-op/publon/6216558/.
  30. Negrao, Rita; Moura, Liane; Duarte, Delfim; Silva, Rafael; Soares, Raquel. "Modulation effect of catechin in angiogenesis and inflammation". The FASEB Journal (2009): https://publons.com/wos-op/publon/10403305/.
  31. Negrao, Rita; Moura, Liane; Soares, Raquel. "Establishing the molecular modulation of the inflammation by xanthohumol and its metabolites in endothelial and smooth muscle cells". The FASEB Journal (2009): https://publons.com/wos-op/publon/10403306/.
Thesis / Dissertation
  1. Moura, Liane. "Development of novel therapeutic approaches for wound healing in diabetes". PhD, 2013. http://hdl.handle.net/10316/23741.

Intellectual property

Provisional application for patent
  1. 2019. "Cross-linked star-shaped self-assembled polypeptides as immunotherapies".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/15 Personalized neoantigen cancer nanovaccine to guide host immune response against melanoma brain metastases XV Spanish-Portuguese Conference on Controlled Drug Delivery
2022/05/23 Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice
(Valencia, Spain)
2022/05/23 Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice
(Valencia, Spain)
2022/04/22 Multivalent polypetide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma International Conference on Pharmaceutics and Novel Drug Delivery Systems
2021/10/15 Precision Multifunctional Nanomedicines to regulate immunosuppression against melanoma brain metastasis LPCC Cutaneous Melanoma: From Where to Where?
(Portugal)
2021/03 Immuno-engineering: nanodelivery systems as tools for immune modulation in cancer PhD Programme in Pharmacy - PhD Advanced Course in “Advanced Drug Delivery”
(Portugal)
2021/01/21 Multivalent branched polypeptide-based nanovaccine as promising immunotherapeutic strategy for melanoma 3rd SPLC-CRS Young Scientists Virtual Meeting
2020/09/23 Nanotechnological approaches for immune modulation against solid cancers. NanoPT 2020
2020/06/29 Nanovaccines as modulators of germinal center responses against cancer CRS Virtual Meeting 2020
2019/09/12 Multi-targeting nano-based platform as an effective immunotherapy against solid tumors. Nanotechnology in Cancer: Engineering for Oncology
(Cambridge, United Kingdom)
2019/05/22 Multivalent polypeptide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma 17th Annual Meeting of the Association for Cancer Immunotherapy - CIMT
(Mainz, Germany)
2018/11/22 Polymeric nano-vaccines improved immune checkpoint anti-tumor efficacy against breast cancer NanoBio&Med 2018
(Barcelona, Spain)
2018/09/18 Polymer conjugates as cancer vaccines FCT PhD Programme i3DU Course on “Advanced Drug Delivery”
Universidade de Lisboa Faculdade de Farmácia (Portugal)
2018/05/28 A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
(Valencia, Spain)
2017/11/24 Impact of multicomponent nano-vaccine on immune modulation against solid tumors NanoBio&Med2017
(Barcelona, Spain)
2017/09/14 Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy – a computational design approach 42nd FEBS Conference
(Jerusalem, Israel)
2017/06/18 Insights on the Impact of Controlled Multicomponent Nanoscale Systems on Immune Modulation Against Solid Tumors Gordon Research Conference “Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer”
(Mount Snow, United States)
2016/01/23 Melanoma cancer vaccine based on multifunctional nanoparticles for antigen delivery and immunomodulation XI Spanish-Portuguese Conference on Controlled Drug Delivery;
(Granada, Spain)
2012/01/27 Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment V SPB Clinical Biochemistry Workshop
(Coimbra, Portugal)
2011/12/19 Neurotensin improves diabetic wound healing via inducible nitric oxide synthase IX Annual Meeting of Center for Neuroscience and Cell Biology
(Coimbra, Portugal)
2011/09/13 Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression 47th EASD Annual Meeting
(Lisbon, Portugal)
2010/03/10 Wound healing in diabetic and iNOS knockout mice: the role of Neurotensin 9º Congresso Português de Diabetes
(Vilamoura, Portugal)
2010/01/28 Neurotensin improves wound healing in diabetic and iNOS knockout mice IV SPB Clinical Biochemistry Workshop
(Faro, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/01 - Current Modulation of tumor-immune microenvironment against cancer
Co-supervisor
 Ciências Farmacêuticas
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Current The Neuro-immune Axis in the Tumor Microenvironment
Supervisor
 Ciências Farmacêuticas
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Current The impact of microbiome in immunotherapy for breast cancer
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Current Collagen as a wound healing material
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Current Sphingosomes: A modified Lipid nanoparticle platform for mRNA delivery
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/10 - Current Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer
Supervisor
2022/09/01 - 2023 Recent nanotechnological approaches for immunotherapy in type 1 diabetes
Supervisor
2022/09/01 - 2022/12/15 Liposomal siRNA Formulation for the Treatment of rheumatoid arthritis
Supervisor
2022/02/01 - 2022/06 Cyclodextrins associated to polymeric nanovaccines for immune cell targeting
Co-supervisor
2022/02/01 - 2022/06 Cyclodextrins associated nanocarriers for immune modulation.
Co-supervisor
2022/02/01 - 2022/06 Nanovaccines for immune modulation in pancreatic cancer
Co-supervisor
Univerza v Ljubljani, Slovenia
2021/09/01 - 2022 Impact of microbiome in cancer nano-immunotherapy
Supervisor
2021/09/01 - 2022 PLGA in situ forming microparticles loaded with nanosized dexamethasone as long-term drug delivery carriers
Supervisor
2020/09/01 - 2021/12 Combination of a multifunctional nanovaccine with modulators of pancreatic cancer microenvironment
Co-supervisor
 M.Sc. in BioPharmaceutical Sciences (FFUL) (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/01 - 2021/04 Nanovaccines for immune modulation in pancreatic cancer
Co-supervisor
2021 - 2021 Recent nanotechnological approaches for immunotherapy in type 1 diabetes
Supervisor
 Master Thesis in Pharmaceutical Sciences at FFUL (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 Impact of microbiome in cancer nano-immunotherapy
Supervisor
 Master Thesis in Pharmaceutical Sciences at FFUL (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021 Detection of mannose moieties on the surface of nanoparticle-based immunotherapy
Co-supervisor
 Biologia Celular e Molecular (Degree)
Universidade Nova de Lisboa, Portugal
2020 - 2021 Development of PCL-based nanovaccine for DC-targeting
Supervisor
2020 - 2021 PCL-based nanovaccines for pancreatic cancer
Co-supervisor
2019/10 - 2020/09 Nanoplatform to modulate dendritic cells and tumor microenvironment against Triple negative breast cancer
Co-supervisor
 Master Thesis in Biopharmaceutical Sciences (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/12 Nanovaccines as tumor microenvironment modulators
Co-supervisor
 Thesis (2nd semester) in Pharmaceutical Sciences(FFUL) (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 - 2019/12 Multi-functional nanovaccine modulates dendritic cell effector function against melanoma
Co-supervisor
 Master Thesis in Biopharmaceutical Sciences (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 - 2019/12 Impact of the modulation of tumor vasculature on cancer vaccine efficacy against colorectal cancer
Co-supervisor
 Master Thesis in Biopharmaceutical Sciences (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/07 Development of polysaccharide-based biodegradable nanovaccines for dendritic cell targeting
Co-supervisor
 Project II (2nd semester) Pharmaceutical Sciences(FFUL) (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2019/02 Optimization of Dendritic Cell- targeting nanovaccines
Co-supervisor
 Project III (1st semester) Pharmaceutical Sciences(FFUL) (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2019/02 Optimization of polymeric based-nanovaccines for dendritic cell targeting
Co-supervisor
 Project I (1st semester) Pharmaceutical Sciences(FFUL) (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/09 - 2018/02 Combination of ß-glucan and mannose as immunomodulators in a multicomponent nanoscale therapeutic cancer vaccine
Co-supervisor
 Project I (1st semester) Pharmaceutical Sciences(FFUL) (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/01/23 - 2019/01/23 2nd SPLC-CRS Young Scientist Meeting (2019/01/23 - 2019/01/23)
Conference (Member of the Scientific Committee)
2012/12/19 - 2012/12/19 IX Annual Meeting of Center for Neuroscience and Cell Biology (2012 - 2012)
Meeting (Member of the Organising Committee)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2018/07/10 - 2018/07/12 Training School “Behavioural Phenotyping in mice: Focus on longitudinal studies in ageing”, Madrid, Spain
Workshop
2017/10/04 - 2017/10/06 Training School “Drug Discovery and Development”, Novartis Campus, Basel, Switzerland
Workshop
2017/01/17 - 2017/01/19 Training School “Introduction to Mathematical and Computational Modelling: from mouse to computer and back”, Eindhoven, Netherlands
Workshop
2011/11/14 - 2011/11/18 Course of “International de la Red Iberoamericana de Nuevos Materiales para el Diseño de Sistemas Avanzados de Liberación de Fármacos en Enfermedades de Alto Impacto Socioeconómico (RIMADEL)”, Santiago de Compostela, Spain
Workshop
2011/02/28 - 2011/03/04 Course of “Fluorescence/ Confocal Microscopy and Flow Cytometry – An integrative approach to cell analysis”, Braga, Portugal
Workshop
2010/04/19 - 2010/04/30 Course of “Laboratory Animal Science - Category C”, accredited by FELASA, Coimbra, Portugal
2009/03/09 - 2009/03/13 Course of “Obesity and Type II Diabetes”, Coimbra, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/12/15 Characterization of breast cancer immunity
(Thesis) Arguer
 Raquel Ventura Rebordão Gouveia (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12 Alginate Rubber Mask as a Double Friend: Cosmetic and Skin Barrier Protector
(Thesis) Main arguer
 Maria Rita Ramos Curva (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/20 Formulation and characterization of drug-loaded PLGA nanoparticles Imaging capabilities of Raman-bas
(Thesis) Main arguer
 Teresa Ramires Ruas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/15 Formulações Lipossomais de Glucocorticóides para o tratamento da Artrite Reumatóide: Preparação, caracterização e avaliação in vitro.
(Thesis) Main arguer
 Tatiana Filipa Rebelo Pereira (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/11/18 Evaluation of neuron/glia network signals using 2D/3D platforms and ALS experimental models
(Thesis) Arguer
 Beatriz da Cunha Suyumov (Master)
2022/11/16 Investigation of a correlation between the stability of polymeric NPs towards temperature and gene knockdown efficiency
(Thesis) Main arguer
 Daniela Azedo (Master)
2022/07/22 Pancreatic Ductal Adenocarcinoma (PDAC): Modulation of Cathepsin S
(Thesis) Arguer
 Ana Marta Reinold´s Nunes (Other)

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024 - Current Genes
2024 - Current Cells
2022 - Current Viruses
2021 - Current Materials Today Bio
2021 - Current Vaccines
2020 - Current DDTR
2020 - Current Pharmaceutics

Association member

Society Organization name Role
2018 - Current Association for Cancer Immunotherapy (CIMT)
2016 - Current European Association for Cancer Research (EACR)
2016 - Current Portuguese Association for Cancer Research (ASPIC)
2015 - Current The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)
2015 - Current Portuguese Society of Biochemistry (SPB)
2015 - Current Federation of European Biochemical Societies (FEBS)
2012 - 2013 Grupo de Investigação Fundamental e Translacional (GIFT)
2012 - 2013 Grupo de Estudos de Pé Diabético em Portugal (GREPED)
2009 - 2013 Portuguese Society of Diabetology (SPD)
2009 - 2013 European Association for the Study of Diabetes (EASD)

Conference scientific committee

Conference name Conference host
2018/09 - 2020/08 SPLC-CRS Young Scientist Meeting

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2021 - Current COST Association External Reviewer
Evaluator

Journal scientific committee

Journal title (ISSN) Publisher
2021 - Current Pharmaceutics

Mentoring / Tutoring

Topic Student name
2023/07/01 - 2023/07/06 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO Célia Borges
2023/07 - 2023/07 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO -Project “De nanopartículas a uma vacina para o cancro” Katarina Coelho
2023/07 - 2023/07 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO -Project “De nanopartículas a uma vacina para o cancro” Luana Favaro
2022/06/27 - 2022/07/01 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2022 – programa Ciência Viva no Laboratório Letícia Soares Barcelos
2022/06/27 - 2022/07/01 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2022 – programa Ciência Viva no Laboratório João Carneiro
2011/02 - 2012/02 A cicatrização de feridas está comprometida durante a fase inicial de cura em ratinhos Balb/c/Rag2-/-IL2R-/- Jenifer Gonçalves
2010/09 - 2011/04 Role of neurotensin in diabetic wound healing Valentina Maio
2009/10 - 2010/07 Neurotensin effect on skin dendritic cells and fibroblasts: repercussions in wound healing and diabetic wound healing Lucilia Pereira da Silva

Other jury / evaluation

Activity description Institution / Organization
2023/08 - Current President of the Jury - call for the award of 1 (One) Master Research Grant within the scope of the project 2022.04506.PTDC, titled “Nano-imunoterapia para regular o perfil imunológico e o microbioma no cancro pancreático Reference: BICNCG/14/FARM-ID/2023 Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2019 Jury of undergraduated student research project - Project II (2nd semester) Pharmaceutical Sciences(FFUL) Universidade de Lisboa Faculdade de Farmácia, Portugal
Distinctions

Award

2022 ERASMUS + - mobility grant, for 13th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
2011 Bolsa Dr. M. M. Almeida Ruas - S.P.D. / Novo Nordisk - "Promoting endothelial progenitor cell function in diabetic wound healing"
Sociedade Portuguesa de Diabetologia, Portugal

Other distinction

2020 Topic Editor - Journal Pharmaceutics
2019 Travel Grant fellowship for 17th CIMT Annual Meeting; Mainz, Germany, 21st – 23rd May 2019
2018 Grant by Cost Action for Training School “Behavioural Phenotyping in mice: Focus on longitudinal studies in ageing”, Madrid, Spain, 10th-12th July 2018
2018 Travel Grant fellowship for 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice. Valencia, Spain; 28th-30th May 2018
2017 Grant by Cost Action for Training School “Drug Discovery and Development”, Novartis Campus, Basel, Switzerland, 4th-6th October 2017
2017 FEBS Bursary for 42nd FEBS Congress; Jerusalem, 10-14 September 2017
2017 Grant by Cost Action for Training School “Introduction to Mathematical and Computational Modelling: from mouse to computer and back”; Eindhoven, Netherlands, 17th-19th January 2017
2016 Travel Grant fellowship for 16th YSF and 41st FEBS Congress; Kusadasi, Turkey; 30 August - 9 September 2016
2014 Post-Doctoral fellowship reference SFRH/BPD/94111/2013 from the Portuguese Foundation for Science and Technology (FCT)
Fundação para a Ciência e a Tecnologia, Portugal
2014 Post-Doctoral fellowship funded by the European project Ref: REGPOT-CT2012-316331-POLARIS
Biomaterials Biodegradables and Biomimetics, Portugal
2012 Travel grant fellowship for 48th EASD Annual Meeting; Berlim; Germany; 1st-5th October 2012
2009 PhD Fellowship reference SFRH/BD/60837/2009 from the Portuguese Foundation for Science and Technology (FCT)
Fundação para a Ciência e a Tecnologia, Portugal
2009 Graduate Research fellowship funded by the FCT project Ref: POCI/SAU-MMO/57598/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008 Grant by IBeSa to attend XVI National Congress of Biochemistry, Ponta Delgada, Portugal, 22th – 25th October 2008