Marta Alexandra Senra Araújo (8012-6C5F-537F)

Curriculum Vitae

Marta Alexandra Senra Araújo

Marta Alexandra Senra Araújo received her Bachelor's degree in Molecular Genetics from the University of Minho in 2017, and her Master's degree in Genetics and Biotechnology from the University of Trás-os-Montes and Alto Douro in 2015. She worked in the Molecular Biology Department of Fairjourney Biologics for one and seven months, specializing in protein production. She is currently involved in the research initiative "Elucidation of the functional roles of lipid metabolism during canine leishmaniasis" at the ICVS-University of Minho. She is engaged in research in the natural sciences, especially in the fields of biology and immunology. His Ciência Vitae CV often uses the following terms to provide context for his scientific, technological and artistic-cultural contributions: Leishmania; oncogenesis; microenvironment; mouse models; infection; metabolism; and infection. A total of three of his articles have been published in peer-reviewed journals.

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Identification

Personal identification

Full name: Marta Alexandra Senra Araújo

Citation names

Araújo, Marta

Author identifiers

Ciência ID: 8012-6C5F-537F
ORCID iD: 0000-0001-8021-0451

Telephones

Mobile phone

915296978 (Personal)

Addresses

Rua Nova n°584, 4755-405, Pereira, Barcelos, Portugal (Personal)

Knowledge fields

Natural sciences - Biological Sciences - Molecular Biology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)
French	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)
German	Beginner (A1)	Elementary (A2)	Beginner (A1)	Elementary (A2)	Beginner (A1)

Education

	Degree	Classification
2023/01/01 - 2027 Ongoing	PhD in Health Sciences (Doutoramento) Universidade do Minho Escola de Medicina, Portugal
2015/09/28 - 2017/12/21 Concluded	Genética Molecular (Mestrado integrado) Major in Biologia Molecular Universidade do Minho, Portugal "Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells" (THESIS/DISSERTATION)	17
2012/09/15 - 2015/07/21 Concluded	Genética e Biotecnologia (Licenciatura) Major in Biologia Molecular Universidade de Trás-os-Montes e Alto Douro, Portugal "Effects of psychopharmaceuticals exposure on RNA/DNA ratios in fish species" (THESIS/DISSERTATION)	15

Affiliation

Science

	Category Host institution	Employer
2021/12/01 - Current	Researcher (Research)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

2019/04/22 - 2020/11/13	Contracted Researcher (Research)	FairJourney Biologics SA, Portugal
	FairJourney Biologics SA, Portugal
2018/01/03 - 2019/01/31	Research Trainee (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Projects

Grant

	Designation	Funders
2023/01/01 - 2026/12/31	Elucidation of the Functional Roles of Lipid Metabolism During Canine Leishmaniasis PTDC/CVT-CVT/4808/2020 PhD Student Fellow	Fundação para a Ciência e a Tecnologia Ongoing
2023/01 - 2026/12	Elucidation of the Functional Roles of Lipid Metabolism During Canine Leishmaniasis 90036DFA	Fundação para a Ciência e a Tecnologia

Contract

	Designation	Funders
2021/12/01 - Current	Elucidação do papel funcional do metabolismo lipídico durante a leishmaniose canina PTDC/CVT-CVT/4808/2020 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Associação para a Inovação e Desenvolvimento da FCT Ongoing
2018/07/01 - 2019/01/31	Determinar o Papel do Microambiente na Modulação do Espetro de Mutações Genéticas Adquiridas Durante o Desenvolvimento de Cancro PTDC/MED-ONC/32592/2017 Estagio Voluntário Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Conference poster

Mendes-Frias, Ana ; Maria C. Vieira; Duarte, Iola F; Rodrigues, Fernando; Leal-Silvestre, RJ. "Female-centric benefits of BCAAs in ulcerative colitis therapy.". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
Araújo, Marta; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Sex Dimorphism in glycerophospholipid metabolism during Leishmania Infection". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
Oliveira, Ana- Rita; Micheli, Consuelo; Millán, Beatriz; Araújo, Marta; Leal-Silvestre, RJ; Rodrigues, Fernando; Castro, Gil; Torrado, Egídio. "Macrophage differentiation and host variability shape tuberculosis outcomes". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Beatriz Costa; Torrado, Egídio; Leal-Silvestre, RJ. "Adipose Tissue and Immune Responses: Insights from Visceral Leishmaniasis". Paper presented in ICVS 2024 Retreat, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Exploring Lipid Influence on Macrophages during Leishmania Infection". Paper presented in ICVS 2024 Retreat, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Unravelling the Influence of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in 1st Symposium on Lipids and Cell Plasticity, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Beatriz Costa; Torrado, Egídio; Leal-Silvestre, RJ. "Uncovering the role of adipose tissue in the immune response to visceral leishmaniasis". Paper presented in 1st Symposium on Lipids and Cell Plasticity, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Torrado, Egídio; Leal-Silvestre, RJ. "Analysis of the Role of Adipose Tissue in the Immune Response to Visceral Leishmaniasis". Paper presented in VII iBiMED symposium, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in XLIX Annual Meeting of the Portuguese Society for Immunology, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in Pathogen immunity and signaling EMBO Meeting, San servolo, Veneza, 8th-12th, 2024.
Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Silvestre, Ricardo. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in Pathogen immunity and signaling - EMBO Workshop, 2024.
Micheli, Consuelo; Mendes-Frias, Ana ; Araújo, Marta; Rodrigues, Fernando; Carvalho, Agostinho; Vilanova, Manuel; Silvestre, Ricardo; Castro, António Gil; Torrado, Egídio. "The key role of alveolar macrophages in shaping the CD4+ T cell activation and control os M. tuberculosis infection". Paper presented in Pathogen immunity and signaling EMBO Meeting, San servolo, Veneza, 8th-12th, 2024.
Mendes-Frias, Ana; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Duarte, Iola F.; Gaifem, Joana; Torrado, Egídio; et al. "Branched-Chain Amino Acids in Ulcerative Colitis: friend or foe?". Paper presented in XLIX Annual Meeting of the Portuguese Society for Immunology,, 2024.
Araújo, Marta; Moreira, Diana; Mesquita, Inês; et al; Leal-Silvestre, RJ. "Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis". Paper presented in EMBO Young Scientists' Forum, 2023.
Mendes-Frias, Ana ; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Gaifem, Joana; Torrado, Egídio; Lopes, Luís; Silvestre, Ricardo. "Unraveling the dynamic effect of branched-chain amino acids in the gut: the influence of sex". Paper presented in EMBO Young Scientists' Forum, 2023.
Mendes-Frias, Ana; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Gaifem, Joana; Torrado, Egídio; Lopes, Luís; Silveste, Ricardo. "Unraveling the dynamic effect of branched-chain amino acids in the gut". Paper presented in Retreat for postgraduate students at the School of Medicine, 2023.
Mendes-Frias, Ana ; Araújo, Marta; Silvestre, Ricardo. "Characterization of Leishmania donovani infection in the gut: from the epithelial barrier to the immune system". Paper presented in Leishmaniasis 2022, 2022.

Journal article

Araújo, Marta; Moreira, Diana; Mesquita, Inês; Ferreira, Carolina; Mendes-Frias, Ana; Barros-Carvalho, Sónia; Dinis-Oliveira, Ricardo Jorge; et al. "Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis". Immunology 170 4 (2023): 510-526. http://dx.doi.org/10.1111/imm.13686.
10.1111/imm.13686
Fernández-García, Miguel; Mesquita, Inês; Ferreira, Carolina; Araújo, Marta; Saha, Bhaskar; Rey-Stolle, Ma Fernanda; García, Antonia; Silvestre, Ricardo; Barbas, Coral. "Leishmania donovani Induces Multiple Dynamic Responses in the Metabolome Associated with Amastigote Differentiation and Maturation Inside the Human Macrophage". Journal of Proteome Research 22 7 (2023): 2256-2270. http://dx.doi.org/10.1021/acs.jproteome.2c00845.
10.1021/acs.jproteome.2c00845
Ghezzo, Marinella N; Fernandes, Mónica T; Pacheco-Leyva, Ivette; Rodrigues, Pedro M; Machado, Rui S; Araújo, Marta A S; Kalathur, Ravi K; et al. "FoxN1-dependent thymic epithelial cells promote T-cell leukemia development". Carcinogenesis 39 12 (2018): 1463-1476. http://dx.doi.org/10.1093/carcin/bgy127.
10.1093/carcin/bgy127

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/10/12	Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis	EMBO Young Scientists' Forum (Lisboa, Portugal)
2023/03/29	Dysregulation of glycerophospholipid metabolism during Leishmania donovani infection contributes to a pro-inflammatory phenotype of infected macrophages.	XLVIII SPI Annual Meeting 2023 SPI (Portugal)
2022/10/24	Elucidation of the functional roles of lipid metabolism during visceral Leishmania infection.	3rd International Caparica Conference on Leishmaniasis 2022 The BIOSCOPE (Lisboa, Portugal)
2022/04/21	Elucidation of the functional roles of lipid metabolism during visceral Leishmania infection	XLVII Annual Meeting of the Portuguese Society for Immunology SPI (Lisboa, Portugal)
2018/05/11	Leukemic T cells stimulate NF-¿B signaling in stromal cells through lymphotoxin-ß receptor stimulation.	3rd ASPIC Internation Congress Fundação Calouste Gulbenkian (Lisboa, Portugal)
2017/11/09	“Leukemic T cells stimulate NF-¿B signaling in stromal cells through lymphotoxin-ß receptor stimulation	I3s (Povoa de Varzim, Portugal)
2017/06/01	Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells	SINAL ASPIC (Lisboa, Portugal)
2017/05/11	Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells	24th Cancer Meeting I3s (Porto, Portugal)
2017/03/17	Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells	T-ALL Workshop University of Leuven (Leuven, Belgium)
2016/11/10	Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells	5th i3S Annual Meeting I3s (Povoa de Varzim, Portugal)
2015/07/14	Effects of psychopharmaceuticals exposure on RNA/DNA ratios in fish species	CICTA Universidade de Tras-os Montes e Alto Douro (Vila Real, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2022/05/01 - 2022/07/25	Elucidating the functional role of lipid metabolism metabolism during visceral leishmaniasis Co-supervisor of Joana Rita Albuquerque Araújo	Bachelor (Degree) Universidade do Minho Escola de Medicina, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2024/10/15 - 2024/10/15	Single Cell Multiomics Oficina (workshop) Workshop	Single Cell Multiomics Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/10/07 - 2024/10/09	Intro to BioImage Analysis with Python for Life Scientists Workshop	Intro to BioImage Analysis with Python for Life Scientists -A distributed in-person training course Euro-BioImaging, Finland
2024/04/08 - 2024/04/13	Pathogen immunity and signaling, 2024 Workshop	EMBO Workshop: Pathogen immunity and signaling, 2024 Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany
2017/03/17 - 2017/03/19	T-ALL Workshop Workshop	T-ALL Workshop Katholieke Universiteit Leuven Faculteit Geneeskunde, Belgium

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2022/01/06 - Current	TÉCNICAS DE CARATERIZAÇÃO EM CIÊNCIAS E TECNOLOGIA I TÉCNICAS DE CARATERIZAÇÃO EM CIÊNCIAS E TECNOLOGIA II (Bio)Etica e propriedade intelectual em investigação Seguranca e Saude em contextos de investigação cientifica Empreendedorismo e Investigação Cientifica Principios básicos de Gestao Cientifica e Financeira de projectos	Curso de Formação Especializada em Fundamentos para a Investigação Científica (Outros)	Universidade do Minho, Portugal
2024/02/28 - 2024/04/22	3rd Advanced Course on Fluorescence Microscopy & Image Analysis	(Outros)	Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2022/03/25 - 2022/04/21	This course aims to enable professionals or academic researchers to use Python as a tool to support data science projects, with the aim of improving decision-making. This program is the introductory level in this area and aims to explain how the Python programming language and SQL work. Module 0: Installation and Configuration Module 1: Introduction to Data Science with Python Module 2: Exploratory analysis and data processing Module 3: Dataset processing Module 4: SQL Module 5: Case studies	Python em Data Science Da Análise de Dados à Tomada de Decisão Nível Introdutório/Intermédio	Gades Solutions, Portugal
2017/04/07 - 2017/04/08	Theoretical-practical course on hematology research	Theoretical-practical course on hematology research (Outros)	Universidade do Porto Centro de Investigação Farmacológica e Inovação Medicamentosa, Portugal
2017/02/01 - 2017/03/30	Introductory course laboratory animal science	Introductory course laboratory animal science (Outros)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Mentoring / Tutoring

	Topic	Student name
2023/12/01 - 2024/03/15	Analysis of the Role of Adipose Tissue in the Immune Response to Visceral Leishmaniasis março de	Ana Rita da Cunha Martins Analysis