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Marta Alexandra Senra Araújo received her Bachelor's degree in Molecular Genetics from the University of Minho in 2017, and her Master's degree in Genetics and Biotechnology from the University of Trás-os-Montes and Alto Douro in 2015. She worked in the Molecular Biology Department of Fairjourney Biologics for one and seven months, specializing in protein production. She is currently involved in the research initiative "Elucidation of the functional roles of lipid metabolism during canine leishmaniasis" at the ICVS-University of Minho. She is engaged in research in the natural sciences, especially in the fields of biology and immunology. His Ciência Vitae CV often uses the following terms to provide context for his scientific, technological and artistic-cultural contributions: Leishmania; oncogenesis; microenvironment; mouse models; infection; metabolism; and infection. A total of three of his articles have been published in peer-reviewed journals.
Identification

Personal identification

Full name
Marta Alexandra Senra Araújo

Citation names

  • Araújo, Marta

Author identifiers

Ciência ID
8012-6C5F-537F
ORCID iD
0000-0001-8021-0451

Telephones

Mobile phone
  • 915296978 (Personal)

Addresses

  • Rua Nova n°584, 4755-405, Pereira, Barcelos, Portugal (Personal)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
German Beginner (A1) Elementary (A2) Beginner (A1) Elementary (A2) Beginner (A1)
Education
Degree Classification
2023/01/01 - 2027
Ongoing
PhD in Health Sciences (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
2015/09/28 - 2017/12/21
Concluded
Genética Molecular (Mestrado integrado)
Major in Biologia Molecular
Universidade do Minho, Portugal
"Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells" (THESIS/DISSERTATION)
17
2012/09/15 - 2015/07/21
Concluded
Genética e Biotecnologia (Licenciatura)
Major in Biologia Molecular
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Effects of psychopharmaceuticals exposure on RNA/DNA ratios in fish species" (THESIS/DISSERTATION)
15
Affiliation

Science

Category
Host institution
Employer
2021/12/01 - Current Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/04/22 - 2020/11/13 Contracted Researcher (Research) FairJourney Biologics SA, Portugal
FairJourney Biologics SA, Portugal
2018/01/03 - 2019/01/31 Research Trainee (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Projects

Grant

Designation Funders
2023/01/01 - 2026/12/31 Elucidation of the Functional Roles of Lipid Metabolism During Canine Leishmaniasis
PTDC/CVT-CVT/4808/2020
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01 - 2026/12 Elucidation of the Functional Roles of Lipid Metabolism During Canine Leishmaniasis
90036DFA
Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2021/12/01 - Current Elucidação do papel funcional do metabolismo lipídico durante a leishmaniose canina
PTDC/CVT-CVT/4808/2020
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
2018/07/01 - 2019/01/31 Determinar o Papel do Microambiente na Modulação do Espetro de Mutações Genéticas Adquiridas Durante o Desenvolvimento de Cancro
PTDC/MED-ONC/32592/2017
Estagio Voluntário
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Mendes-Frias, Ana ; Maria C. Vieira; Duarte, Iola F; Rodrigues, Fernando; Leal-Silvestre, RJ. "Female-centric benefits of BCAAs in ulcerative colitis therapy.". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
  2. Araújo, Marta; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Sex Dimorphism in glycerophospholipid metabolism during Leishmania Infection". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
  3. Oliveira, Ana- Rita; Micheli, Consuelo; Millán, Beatriz; Araújo, Marta; Leal-Silvestre, RJ; Rodrigues, Fernando; Castro, Gil; Torrado, Egídio. "Macrophage differentiation and host variability shape tuberculosis outcomes". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
  4. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Beatriz Costa; Torrado, Egídio; Leal-Silvestre, RJ. "Adipose Tissue and Immune Responses: Insights from Visceral Leishmaniasis". Paper presented in ICVS 2024 Retreat, 2024.
  5. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Exploring Lipid Influence on Macrophages during Leishmania Infection". Paper presented in ICVS 2024 Retreat, 2024.
  6. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Unravelling the Influence of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in 1st Symposium on Lipids and Cell Plasticity, 2024.
  7. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Beatriz Costa; Torrado, Egídio; Leal-Silvestre, RJ. "Uncovering the role of adipose tissue in the immune response to visceral leishmaniasis". Paper presented in 1st Symposium on Lipids and Cell Plasticity, 2024.
  8. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Torrado, Egídio; Leal-Silvestre, RJ. "Analysis of the Role of Adipose Tissue in the Immune Response to Visceral Leishmaniasis". Paper presented in VII iBiMED symposium, 2024.
  9. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in XLIX Annual Meeting of the Portuguese Society for Immunology, 2024.
  10. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in Pathogen immunity and signaling EMBO Meeting, San servolo, Veneza, 8th-12th, 2024.
  11. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Silvestre, Ricardo. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in Pathogen immunity and signaling - EMBO Workshop, 2024.
  12. Micheli, Consuelo; Mendes-Frias, Ana ; Araújo, Marta; Rodrigues, Fernando; Carvalho, Agostinho; Vilanova, Manuel; Silvestre, Ricardo; Castro, António Gil; Torrado, Egídio. "The key role of alveolar macrophages in shaping the CD4+ T cell activation and control os M. tuberculosis infection". Paper presented in Pathogen immunity and signaling EMBO Meeting, San servolo, Veneza, 8th-12th, 2024.
  13. Mendes-Frias, Ana; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Duarte, Iola F.; Gaifem, Joana; Torrado, Egídio; et al. "Branched-Chain Amino Acids in Ulcerative Colitis: friend or foe?". Paper presented in XLIX Annual Meeting of the Portuguese Society for Immunology,, 2024.
  14. Araújo, Marta; Moreira, Diana; Mesquita, Inês; et al; Leal-Silvestre, RJ. "Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis". Paper presented in EMBO Young Scientists' Forum, 2023.
  15. Mendes-Frias, Ana ; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Gaifem, Joana; Torrado, Egídio; Lopes, Luís; Silvestre, Ricardo. "Unraveling the dynamic effect of branched-chain amino acids in the gut: the influence of sex". Paper presented in EMBO Young Scientists' Forum, 2023.
  16. Mendes-Frias, Ana; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Gaifem, Joana; Torrado, Egídio; Lopes, Luís; Silveste, Ricardo. "Unraveling the dynamic effect of branched-chain amino acids in the gut". Paper presented in Retreat for postgraduate students at the School of Medicine, 2023.
  17. Mendes-Frias, Ana ; Araújo, Marta; Silvestre, Ricardo. "Characterization of Leishmania donovani infection in the gut: from the epithelial barrier to the immune system". Paper presented in Leishmaniasis 2022, 2022.
Journal article
  1. Araújo, Marta; Moreira, Diana; Mesquita, Inês; Ferreira, Carolina; Mendes-Frias, Ana; Barros-Carvalho, Sónia; Dinis-Oliveira, Ricardo Jorge; et al. "Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis". Immunology 170 4 (2023): 510-526. http://dx.doi.org/10.1111/imm.13686.
    10.1111/imm.13686
  2. Fernández-García, Miguel; Mesquita, Inês; Ferreira, Carolina; Araújo, Marta; Saha, Bhaskar; Rey-Stolle, Ma Fernanda; García, Antonia; Silvestre, Ricardo; Barbas, Coral. "Leishmania donovani Induces Multiple Dynamic Responses in the Metabolome Associated with Amastigote Differentiation and Maturation Inside the Human Macrophage". Journal of Proteome Research 22 7 (2023): 2256-2270. http://dx.doi.org/10.1021/acs.jproteome.2c00845.
    10.1021/acs.jproteome.2c00845
  3. Ghezzo, Marinella N; Fernandes, Mónica T; Pacheco-Leyva, Ivette; Rodrigues, Pedro M; Machado, Rui S; Araújo, Marta A S; Kalathur, Ravi K; et al. "FoxN1-dependent thymic epithelial cells promote T-cell leukemia development". Carcinogenesis 39 12 (2018): 1463-1476. http://dx.doi.org/10.1093/carcin/bgy127.
    10.1093/carcin/bgy127
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/12 Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis EMBO Young Scientists' Forum
(Lisboa, Portugal)
2023/03/29 Dysregulation of glycerophospholipid metabolism during Leishmania donovani infection contributes to a pro-inflammatory phenotype of infected macrophages. XLVIII SPI Annual Meeting 2023
SPI (Portugal)
2022/10/24 Elucidation of the functional roles of lipid metabolism during visceral Leishmania infection. 3rd International Caparica Conference on Leishmaniasis 2022
The BIOSCOPE (Lisboa, Portugal)
2022/04/21 Elucidation of the functional roles of lipid metabolism during visceral Leishmania infection XLVII Annual Meeting of the Portuguese Society for Immunology
SPI (Lisboa, Portugal)
2018/05/11 Leukemic T cells stimulate NF-¿B signaling in stromal cells through lymphotoxin-ß receptor stimulation. 3rd ASPIC Internation Congress
Fundação Calouste Gulbenkian (Lisboa, Portugal)
2017/11/09 “Leukemic T cells stimulate NF-¿B signaling in stromal cells through lymphotoxin-ß receptor stimulation
I3s (Povoa de Varzim, Portugal)
2017/06/01 Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells SINAL
ASPIC (Lisboa, Portugal)
2017/05/11 Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells 24th Cancer Meeting
I3s (Porto, Portugal)
2017/03/17 Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells T-ALL Workshop
University of Leuven (Leuven, Belgium)
2016/11/10 Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells 5th i3S Annual Meeting
I3s (Povoa de Varzim, Portugal)
2015/07/14 Effects of psychopharmaceuticals exposure on RNA/DNA ratios in fish species CICTA
Universidade de Tras-os Montes e Alto Douro (Vila Real, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2022/05/01 - 2022/07/25 Elucidating the functional role of lipid metabolism metabolism during visceral leishmaniasis
Co-supervisor of Joana Rita Albuquerque Araújo
Bachelor (Degree)
Universidade do Minho Escola de Medicina, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/10/15 - 2024/10/15 Single Cell Multiomics Oficina (workshop)
Workshop
Single Cell Multiomics
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/10/07 - 2024/10/09 Intro to BioImage Analysis with Python for Life Scientists
Workshop
Intro to BioImage Analysis with Python for Life Scientists -A distributed in-person training course
Euro-BioImaging, Finland
2024/04/08 - 2024/04/13 Pathogen immunity and signaling, 2024
Workshop
EMBO Workshop: Pathogen immunity and signaling, 2024
Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany
2017/03/17 - 2017/03/19 T-ALL Workshop
Workshop
T-ALL Workshop
Katholieke Universiteit Leuven Faculteit Geneeskunde, Belgium

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/01/06 - Current TÉCNICAS DE CARATERIZAÇÃO EM CIÊNCIAS E TECNOLOGIA I TÉCNICAS DE CARATERIZAÇÃO EM CIÊNCIAS E TECNOLOGIA II (Bio)Etica e propriedade intelectual em investigação Seguranca e Saude em contextos de investigação cientifica Empreendedorismo e Investigação Cientifica Principios básicos de Gestao Cientifica e Financeira de projectos Curso de Formação Especializada em Fundamentos para a Investigação Científica (Outros) Universidade do Minho, Portugal
2024/02/28 - 2024/04/22 3rd Advanced Course on Fluorescence Microscopy & Image Analysis (Outros) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2022/03/25 - 2022/04/21 This course aims to enable professionals or academic researchers to use Python as a tool to support data science projects, with the aim of improving decision-making. This program is the introductory level in this area and aims to explain how the Python programming language and SQL work. Module 0: Installation and Configuration Module 1: Introduction to Data Science with Python Module 2: Exploratory analysis and data processing Module 3: Dataset processing Module 4: SQL Module 5: Case studies Python em Data Science Da Análise de Dados à Tomada de Decisão Nível Introdutório/Intermédio Gades Solutions, Portugal
2017/04/07 - 2017/04/08 Theoretical-practical course on hematology research Theoretical-practical course on hematology research (Outros) Universidade do Porto Centro de Investigação Farmacológica e Inovação Medicamentosa, Portugal
2017/02/01 - 2017/03/30 Introductory course laboratory animal science Introductory course laboratory animal science (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Mentoring / Tutoring

Topic Student name
2023/12/01 - 2024/03/15 Analysis of the Role of Adipose Tissue in the Immune Response to Visceral Leishmaniasis março de Ana Rita da Cunha Martins Analysis