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Bruno Neves (BN) earned his degree in Pharmaceutical Sciences from the University of Coimbra in 2006 and subsequently pursued a Ph.D. in Molecular and Cellular Biology at the Centre for Neurosciences and Cell Biology, University of Coimbra, and the Innate Immunity and Inflammation Unit, Instituto de Biologia y Genética Molecular, University of Valladolid, Spain, completing it in 2011. From 2011 to 2018, BN served as an invited professor at the Chemistry Department of the University of Aveiro and the Faculty of Pharmacy at the University of Coimbra. Since 2018, BN held the position of Assistant Professor and Director of the Biomedical Sciences degree at the Medical Sciences Department of the University of Aveiro. From the same date, he is a Principal Investigator and member of the Scientific Board at the Institute of Biomedicine (iBiMED). During his Ph.D, BN made significant contributions to the field of Dendritic Cell (DCs) immunobiology by unraveling the molecular mechanisms by which haptens and pathogen/danger associated molecular patterns trigger DC activation. These pioneering findings allowed the development of novel dendritic cell-based in vitro test for identifying haptens in the cosmetic and chemistry industries. This achievement resulted in an international patent (WO/2012/148297) and the establishment of a start-up company, Toxfinder Lda, where BN serve as the co-founder and CEO. BN scientific and entrepreneurial endeavors have been recognized with several prizes, including the Bolsa de Ignição INOV.Capital, Caixa de Crédito Agricola Award for innovation and entrepreneurship, and the COTEC Idea to Product Portugal Competition. Throughout his scientific journey, BN have played key roles in coordinating or participating as a team member in 22 national and international R&D projects allowing him to secure the mentorship of 2 post-doctoral researchers, 10 Ph.D. students (with 6 ongoing), 28 M.Sc. students (with 4 ongoing), and 19 B.Sc. students. BN authored 8 book chapters and published over 70 peer-reviewed manuscripts in journals such as Journal for Immunotherapy of Cancer, American Journal of Pathology, Small, Advanced Functional Materials, Pharmacological Research, and Frontiers in Immunology, accumulating over 5600 citations, and achieving an h-index of 23 (Scopus). The scientific findings generated within these works led to 3 international patents (WO/2024/013711, WO/2023/148531 and WO/2012/148297) and 1 international patent application (P1303-7WO). Currently, BN primary focus is on developing innovative antitumor immunotherapeutic strategies and understanding how danger sensing mechanisms and stress responses are integrated into innate immune cells. He is actively engaged in translational research and have collaborated extensively with a leading national pharmaceutical company, Tecnimede Pharmaceutical Group, in the establishment of a pilot-scale facility to produce clinical grade cellular products (UpCells). Within the framework of this collaboration, BN is spearheading the coordination of the development of a next-generation DC-based vaccine for pancreatic and pulmonary tumors. BN is actively involved as a referee for several leading journals in the field of Biomedicine and as an Expert Evaluator for institutions such as the Dutch Cancer Society (KWF), Portuguese National Agency for Innovation and Wellcome Trust.
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Identification

Personal identification

Full name
Bruno Miguel Rodrigues Neves

Citation names

  • Neves, Bruno

Author identifiers

Ciência ID
7D1E-5EFB-7234
ORCID iD
0000-0001-7391-3124
Researcher Id
L-2557-2016
Scopus Author Id
21734628100

Email addresses

  • bruno.neves@ua.pt (Professional)

Addresses

  • University of Aveiro. Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, Agra do Crasto - edifício 30, 3810-193 A, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
French Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Intermediate (B1) Advanced (C1) Intermediate (B1) Advanced (C1)
Education
Degree Classification
2011/01/11
Concluded
 Farmácia (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Dendritic cell modulation by allergenic and infectious stimuli" (THESIS/DISSERTATION)
 Approved with Distinction and Praise by unanimity
2006
Concluded
 Licenciatura pré-Bolonha (Licenciatura)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"n/a" (THESIS/DISSERTATION)
 16/20
2001
Concluded
 ciências (Ensino secundário)
Agrupamento Escolas da Mealhada, Portugal
"n/a" (THESIS/DISSERTATION)
 18.4/20
Affiliation

Science

Category
Host institution 		Employer
2018/03 - Current Principal Investigator (Research) Universidade de Aveiro Instituto de Biomedicina, Portugal
2014/09/01 - 2018 Researcher (Research) CNC.IBILI, Portugal
2011/09/01 - 2015/08/31 Researcher (Research) Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018/04/15 - Current Assistant Professor (University Teacher) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 - 2018/02/01 Invited Assistant Professor (University Teacher) Universidade de Coimbra Faculdade de Farmácia, Portugal
2011/09/01 - 2015/08/31 Invited Assistant Professor (University Teacher) Universidade de Aveiro Departamento de Química, Portugal

Positions / Appointments

Category
Host institution 		Employer
2018/10/17 - Current Director of the Biomedical Science degree Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Others

Category
Host institution 		Employer
2011/09/01 - Current Founder and CEO Toxfinder Lda, Portugal
2007/01/01 - 2011/01/11 PhD Student CNC.IBILI, Portugal
2006/05/02 - 2006/12/31 Curricular Traineeship CNC.IBILI, Portugal
2006/03/01 - 2006/05/01 Curricular Traineeship Centro Hospitalar e Universitário de Coimbra EPE, Portugal
Projects

Grant

Designation Funders
2021/01/04 - Current Dissecting the mechanism by which haptens disrupt lysosomes and activate NLRP3 inflammasome: the missing link in chemical allergic reactions physiopathology
EPIC-XS project 265
Principal investigator
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Horizon 2020 European Innovation Council Fast Track to Innovation
Ongoing
2020/01/06 - 2020/03/31 Development of a new medical device for prevention of allergic contact dermatitis
PD/BDE/142926/2018
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT
Ongoing
2014 - 2015 Exosomes: putative biomarkers for respiratory and cutaneous allergens hazard
grant agreement number 262067
Researcher
European Commission Seventh Framework Programme for Research and Technological Development Joint Technology Initiatives
Concluded
2014 - 2015 Generation of a novel dendritic cell-based vaccine against glioblastoma
INOV.C
Researcher
Universidade de Coimbra

Contract

Designation Funders
2018/08/06 - Current Cellular immunotherapy targeting cancer stem cells
ImmunoDCs@CancerStemCells
Principal investigator
Toxfinder Lda, Portugal
 Grupo Tecnimede
Ongoing
2018 - Current Optimization of a defined approach for skin sensitizer potency integrating in silico, in chemico and in vitro cell data for classifying chemicals accordingly to five categories (extreme, strong, moderate, weak and non-sensitizer)
Cosmetics Europe
Principal investigator
Toxfinder Lda, Portugal
 Cosmetics Europe
Concluded
2023/03/06 - 2026/03/05 Transient pluripotent states as novel reservoirs of cancer-specific antigens
2022.01199.PTDC
Researcher
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022 - 2023 Improving the manufacturing of mRNA vaccines applying ionic liquids and integrated production-clarification processe
EXPL/BII-BTI/0731/2021
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2021 - 2022 The role of long non-coding RNAs on the molecular circuitry and metabolic adaptation of breast cancer.
PTDC/BTM-TEC/28534/2017
Researcher
Concluded
2020/10/15 - 2021/10/14 SIARC- Integrated High Speed Tracking Automation Solutions fo COVID-19
CENTRO-O1-02B7-FEDER-069749
Researcher
European Regional Development Fund
Concluded
2018 - 2020/12/31 PAGE - Protein aggregation throughout life
CENTRO-01-0145-FEDER-000003
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 European Regional Development Fund
Concluded
2019 - 2020 N2BD- Development of a Novel Nose-to-Brain multifunctional nanoplatform for the treatment of Depression and prevention of pharmacoresistance development
CENTRO-01-0145-FEDER-030752
Researcher
Associação para a Inovação e Desenvolvimento da FCT
Concluded
2019/06 - 2019/12 4Epilepsy- Promoting the quality of life of epileptic patients through personalized medicine
PTDC/SAU-SER/30478/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT
Concluded
2018 - 2019 Allergens4AD-Skin allergens: molecules with an improbable therapeutic application for Alzheimer's disease
PTDC/MED-FAR/29369/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT
Concluded
2018 - 2019 Giardia lamblia extracellular vesicles in modulation of host immune cells: potential application of Giardia EVs against intestinal inflammation
PTDC/SAU-PAR/31506/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT
Concluded
2014 - 2017 In chemico, in silico and in vitro dendritic cell modeling to predict human respiratory allergens
2014-07
Researcher
Johns Hopkins University Center for Alternatives to Animal Testing
Concluded
2014 - 2016 Development and validation of a pilot laboratory for cell therapy (UpCells)
5378/2014
Researcher
Grupo Tecnimede, Portugal

Universidade de Coimbra, Portugal
Agência Nacional de Inovação SA
Concluded
2014 - 2015/06 ToxVitroTesting: Replacement of in vivo toxicity tests by equivalent in vitro tests
ToxVitroTesting 38977/2014
Principal investigator
Agência Nacional de Inovação SA
Concluded
2010 - 2013 In vitro alternative approach for chemical skin sensitization hazard: an EU legislation demand
PTDC/SAU-OSM/099762/2008
PhD Student Fellow
Associação para a Inovação e Desenvolvimento da FCT
2009 - 2013 Anti-inflammatory mechanism and properties of medicinal plants: a multidisciplinary research for their validation and utilization as a source of phytopharmaceuticals
FCT PTDC/SAU-FCF/105429/2008
PhD Student Fellow
Associação para a Inovação e Desenvolvimento da FCT
2006 - 2010 ROLE OF DENDRITIC CELLS IN LEISHMANIASIS: intracellular signalling pathways activated by virulent and attenuated parasite Leismania infantum
FCT PTDC/SAU-FCF/67351/2006
PhD Student Fellow
Associação para a Inovação e Desenvolvimento da FCT
2007/08/16 - 2009/12/31 PAPEL DAS CÉLULAS DENDRITICAS NA LEISHMANIOSE: estudos de sinalização intracelular na infecção pelo parasita Leismania infantum virulento ou atenuado.
PTDC/SAU-FCF/67351/2006
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Neves, Bruno M.; Almeida, Catarina R.. "Signaling Pathways Governing Activation of Innate Immune Cells". In Tissue-Specific Cell Signaling, 93-131. Springer International Publishing, 2020.
    10.1007/978-3-030-44436-5_4
  2. Neves, Bruno. "Metabolismo do tecido conjuntivo: A diversidade metabólica dos elementos figurados do sangue.". In Bioquímica Fisiológica: Integração do Metabolismo na Especialização dos Órgãos.. Portugal: Afrontamento, 2020.
    Published
  3. Calmeiro, João; Carrascal, Mylene; Gomes, Célia; Falcão, Amílcar; Cruz, Maria Teresa; Neves, Bruno Miguel. "Highlighting the Role of DC-NK Cell Interplay in Immunobiology and Immunotherapy". In Dendritic Cells. InTech, 2018.
    10.5772/intechopen.78804
  4. Francisco, V.; Costa, G.; Neves, B.M.; Cruz, M.T.; Batista, M.T.. "Antiinflammatory Activity of Polyphenols on Dendritic Cells". In Polyphenols: Prevention and Treatment of Human Disease (second edition), 395-415. Elsevier, 2018.
    10.1016/b978-0-12-813008-7.00031-x
  5. Neves, Bruno Miguel; Martins, João Demétrio; Ferreira, Isabel; Silva, Ana; Cruz, Maria Teresa. "In Vitro Dendritic Cell-Based Test for Skin Sensitizers Identification and Potency Estimation". In Alternatives for Dermal Toxicity Testing, 417-435. Springer International Publishing, 2017.
    10.1007/978-3-319-50353-0_29
  6. Neves, Bruno. "Anti-Inflammatory Activity of the Honeybee Plant- Derived Products Honey, Pollen and Propolis". In Chemistry, Biology and Potential Applications of Honeybee Plant- Derived Products, 313-346. BENTHAM SCIENCE PUBLISHERS, 2016.
    10.2174/9781681082370116010012
  7. Francisco, V.; Costa, G.; Neves, B.M.; Cruz, M.T.; Batista, M.T.. "Anti-Inflammatory Activity of Polyphenols on Dendritic Cells". In Polyphenols in Human Health and Disease, 373-392. Elsevier, 2014.
    10.1016/b978-0-12-398456-2.00028-1
  8. Miguel, Bruno; Celeste, Maria; Teresa, Maria. "Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View". In Protein Kinases. InTech, 2012.
    10.5772/37771
Conference abstract
  1. Neves, Bruno. "Unveiling new molecules with preventive properties for the management of allergic contact dermatitis". Paper presented in ESCD CONGRESS 2022, 2022.
    Published
  2. Cátia Sousa; Neves, Bruno; Leitão, Alcino Jorge; Mendes, Alexandrina Ferreira. ""JNK1 inhibition contributes to the antiinflammatory activity of (R)-(-)-carvone"". Paper presented in 52nd Annual Meeting of the Portuguese Society of Pharmacology, Porto, 2022.
  3. Neves, Bruno. "Prevention of allergic contact dermatitis, myth or reality? Avoiding contact allergens: from basic research to development of a new medical device". Paper presented in EUROTOX 2021, Copenhagen, 2021.
  4. Neves, Bruno. "Dendritic-cell based immunotherapy targeting pancreatic and NSCLC cancer stem cells". Paper presented in iTOC7 - The 7th Leading International Cancer Immunotherapy Conference in Europe, 2020.
    Published
  5. Neves, Bruno. "The role of endoplasmic reticulum stress in the innate immune system in bipolar disorder". Paper presented in 27th European Congress of Psychiatry, Warsaw, 2019.
    Published
  6. Neves, Bruno. "Development of a novel dendritic cell-based immunotherapy targeting cancer stem cells". Paper presented in 2019 ASCO Annual Meeting, Chicago, 2019.
    Published
  7. Neves, Bruno. "Impact of different GMP media in the production of dendritic cells for next-generation cancer immunotherapy: Functional and metabolic characterization". Paper presented in ESMO Immuno-Oncology Congress, Geneve, 2018.
    Published
  8. Neves, Bruno. "Respiratory and skin allergies: a matter of differential ROS origin and kinetics?". Paper presented in 14th Congress of the European Society of Contact Dermatitis (ESCD), 18–20 October 2018, Milan, Italy, Milan, 2018.
    Published • 10.1111/cod.13111
  9. Neves, Bruno; Silvestre, Ricardo; Cunha, Joana; Tavares, Joana; Resende, Mariana; Ouaissi, Ali; Lopes, MC; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela. "Immunomodulation of dendritic cells by virulent and attenuated Leishmania infantum strains". Paper presented in 2nd European Congress of Immunology, Berlim, 2009.
    Published
Conference poster
  1. Faria, Clarissa Perez; Ferreira, Bárbara; Ágata Lourenço; Mateus, Daniela; Sebastião, Ana Isabel; Neves, Bruno; Cruz, Maria Teresa; Maria do Céu Rodrigues de Sousa. Corresponding author: Maria do Céu Rodrigues de Sousa. "Extracellular Vesicles of Giardia lamblia modulate host cell innate immunity: new avenues for the exploitation of novel therapies". Paper presented in 33rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2023.
  2. Conde, Tiago A.; Bruna Filipa Brito Neves; Couto, Daniela; Tânia Sofia Rodrigues de Melo; Margarida Costa; Joana Silva; Neves, Bruno; Domingues, Pedro; Domingues, Maria Rosário. "Evaluation of microalgae fatty acids and antioxidant activity contribute to the valorization of these microorganisms as biofactories of healthy lipids". Paper presented in 16th GERLI International Lipidomics Meeting, 2021.
  3. Conde, Tiago A.; Couto, Daniela; Melo, Tânia; Moreira, Ana S.P.; Costa, Margarida; Silva, Joana; Neves, Bruno; Domingues, Pedro; Domingues, M. Rosário. "Production of green, sustainable and healthy polar lipid extracts of Chlorococcum amblystomatis using ultrasound-assisted extraction". 2021.
  4. Bruna Filipa Brito Neves; Conde, Tiago A.; Couto, Daniela; Tânia Sofia Rodrigues de Melo; Neves, Bruno; Margarida Costa; Joana Silva; Domingues, Pedro; Domingues, Maria Rosário. "Screening of specific fatty acid signatures of microalgae towards valorization of sustainable and healthy lipids". Paper presented in Lipids in the Ocean, 2021.
  5. Silva, Ana Cristina Rosa da; Pereira, Marta; Carrascal, Mylene; Brites, Gonçalo Sousa; Neves, Bruno; Moreira, Patricia; Resende, Rosa; et al. "EFFECT OF SKIN ALLERGENS TARGETING NRF2 TRANSCRIPTION FACTOR ACTIVATION ON ALZHEIMER¿S DISEASE HALMARKS". Paper presented in 15th International Conference on Alzheimer's and Parkinson's Diseases (ADPD2021), 2021.
  6. Calmeiro, João; Mylène Carrascal; Luis Mendes; Iola F. Duarte; Célia Gomes; João Serra; Amílcar Falcão; Cruz, Maria Teresa; Neves, Bruno. "Dendritic cell plasticity in cancer immunotherapy: functional and metabolic characterization of the impact of different GMP serum-free media in human-monocyte-derived DCs". Paper presented in 1st Meeting of the French Society of Cancer Immunotherapy, Institut Curie, Paris, France, 2019.
  7. Silva, Ana; Pereira, Marta; Brites, Gonçalo; Neves, Bruno; Moreira, Patricia; Resende, Rosa; Silva, Maria Manuel; et al. "Skin allergens and Alzheimer´s disease: preliminary studies on an (im)probable link". Paper presented in Cell Signalingin Aging and Neurodegenerative Diseases, Coimbra, Portugal, 2019.
  8. Brites, G; Silva, Filipa; Ferreira, Isabel; Silva, Ana; Carrascal, Mylene; Neves, Bruno; Rosete, Teresa. "Managing allergic contact dermatitis: screening of molecules with potential for preventing the disease". Paper presented in 24th World Congress of Dermatology, 2019.
  9. Calmeiro, João; Mylène Carrascal; Luis Mendes; Iola F. Duarte; Célia Gomes; João Serra; Amílcar Falcão; Cruz, Maria Teresa; Neves, Bruno. "Impact of different GMP serum-free media in the plasticity of dendritic cells for clinical use in cancer immunotherapy". Paper presented in 26th Porto Cancer Meeting & Porto-Bordeaux joint meeting: the cancer ecosystem, i3S ¿ Instituto de Investigação e Inovação em Saúde, Porto, Portugal, 2019.
  10. Calmeiro, João; Mylène Carrascal; Luis Mendes; Iola F. Duarte; Célia Gomes; João Serra; Amílcar Falcão; Cruz, Maria Teresa; Neves, Bruno. "Dendritic cells plasticity for clinical use in cancer immunotherapy: functional and metabolic characterization of the impact of different GMP serum-free media in monocyte-derived dendritic cells.". Paper presented in 5th Workshop on Dendritic Cell Biology: antitumoral immunotherapy, from biology to the clinic. Champalimaud Foundation, Lisbon, Portugal, 2019.
  11. Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Morais, S; Madeira, N; Cruz, Maria Teresa; Pereira, Cláudia. "Mitochondria-Associated Membranes: the putative link between cellular stress and inflammasome activation in Bipolar Disorder". Paper presented in Encontro Nacional da Sociedade Portuguesa de Psiquiatria e Saúde Mental (SPPSM)| II Encontro das Secções, 2019.
  12. Pereira, Marta; Silva, Ana; Neves, Bruno; Moreira, Patricia; Silva, Maria Manuel; Santos, Armanda Emanuela; Pereira, Cláudia Fragão; Cruz, Maria Teresa. "Molecules with an improbable therapeutic application for Alzheimer¿s disease". Paper presented in Ageing: models, mechanisms and therapies, Coimbra, Portugal, 2019.
  13. Silva, Ana Cristina Rosa da; Pereira, Marta; Brites, Gonçalo Sousa; Neves, Bruno; Moreira, Patricia; Resende, Rosa; Silva, MMC; et al. "Skin allergens and Alzheimer´s disease: preliminar studies on na (im)probable link". Paper presented in . 8th ECS workshop Calcium Signalin in Aging and Neurodegenerative Diseases, 2019.
  14. Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Madeira, N; Cruz, Maria Teresa; Pereira, Cláudia. "Resposta ao stresse celular em células do sistema imune inato na doença Bipolar". Paper presented in 2º Semina´rio da Sociedade Portuguesa para o Estudo da Saúde Mental - SPESM, 2018.
  15. Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Cruz, Maria Teresa; Pereira, Cláudia. "Role of Mitochondria-Associated Membranes in the endoplasmic reticulum stress response in the innate immune system". Paper presented in MitoPorto International Symposium, 2018.
  16. Resende, Mariana; Moreira, Diana; Cunha, Joana; Augusto, J; Neves, Bruno; Cruz, Maria Teresa; Estaquier, Jerôme; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Leishmania-infected mature dendritic cells polarize CD4+ T cells towards a non-protective T-bet+ INF-gamma+ IL10+ phenotype". Paper presented in 3rd I3S Scientific Retreat, 2012.
  17. Resende, Mariana; Moreira, Diana; Cunha, Joana; Neves, Bruno; Costa-Lima, Sofia; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Infected but not Bystander Dendritic Cells polarize CD4+ T cells towards a non-protective T-bet+ INF-gamma+ IL10+ phenotype". Paper presented in XXXVII Annual Meeting of the Portuguese Society for Immunology, 2011.
  18. Resende, Mariana; Silvestre, Ricardo; Neves, Bruno; Cunha, Joana; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela. "Differential effect of Leishmania infantum on infected and bystander dendritic cells". Paper presented in XXXVI Annual Meeting of the Portuguese Society for Immunology, 2010.
  19. Neves, Bruno; Silvestre, Ricardo; Cunha, Joana; Tavares, Joana; Resende, Mariana; Ouaissi, Ali; Lopes, MC; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela. "Poster PA11/60 Immunomodulation of dendritic cells by virulent and attenuated Leishmania infantum strains". Paper presented in European Congress of Immunology 2009, 2009.
Journal article
  1. Antoine S. Almeida; Bruno M. Neves; Regina M.B.O. Duarte. "Contribution of water-soluble extracts to the oxidative and inflammatory effects of atmospheric aerosols: A critical review". Environmental Pollution (2024): https://doi.org/10.1016/j.envpol.2023.123121.
    10.1016/j.envpol.2023.123121
  2. Tiago Conde; Bruno Neves; Daniela Couto; Tânia Melo; Diana Lopes; Rita Pais; Joana Batista; et al. "Polar Lipids of Marine Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis Mitigate the LPS-Induced Pro-Inflammatory Response in Macrophages". Marine Drugs (2023): https://doi.org/10.3390/md21120629.
    10.3390/md21120629
  3. Maria V. Monteiro; Margarida Henriques-Pereira; Bruno M. Neves; Iola D. Duarte; Vítor M. Gaspar; João F. Mano. "Photo-Compartmentalized Decellularized Matrix-Hyaluronan Hybrid Units for Pancreatic Tumor-Stroma Modeling". Advanced Functional Materials (2023): https://doi.org/10.1002/adfm.202305473.
    10.1002/adfm.202305473
  4. Isabel Ferreira; Gonçalo Brites; Ana Silva; Francisco Caramelo; Bárbara Oliveiros; Bruno Miguel Neves; Maria Teresa Cruz. "Development of an in chemico high-throughput screening method for the identification of skin sensitization potential". Archives of Toxicology (2023): https://doi.org/10.1007/s00204-023-03550-z.
    10.1007/s00204-023-03550-z
  5. Mateus, Daniela; Sebastião, AI; Frasco, Manuela F.; Carrascal, Mylène A.; Falcão, Amílcar; Gomes, Célia M.; Neves, Bruno; Sales, Maria G. F.; Cruz, Maria T.. Corresponding author: Cruz, Maria T.. "Artificial Dendritic Cells: A New Era of Promising Antitumor Immunotherapy". Small (2023): http://dx.doi.org/10.1002/smll.202303940.
    10.1002/smll.202303940
  6. Cátia Sousa; Bruno Miguel Neves; Alcino Jorge Leitão; Alexandrina Ferreira Mendes. "Molecular Mechanisms Underlying the Anti-Inflammatory Properties of (R)-(-)-Carvone: Potential Roles of JNK1, Nrf2 and NF-¿B". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15010249.
    10.3390/pharmaceutics15010249
  7. Cariny Polesca; Helena Passos; Bruno M. Neves; João A.P. Coutinho; Mara G. Freire. "Valorization of chicken feathers using aqueous solutions of ionic liquids". Green Chemistry (2023): http://dx.doi.org/10.1039/d2gc04477c.
    10.1039/d2gc04477c
  8. Conde, Tiago; Aveiro, Susana; Melo, Tania; Santos, Tamara; Neves, Bruno; Domingues, Pedro; Varela, Joao; Pereira, Hugo; Domingues, M. Rosario. "Cross-stress lipid response of Tetraselmis striata CTP4 to temperature and salinity variation". Algal Research (2023): https://publons.com/wos-op/publon/63501697/.
    10.1016/J.ALGAL.2023.103218
  9. Gonçalo Brites; João Basso; Margarida Miranda; Bruno Miguel Neves; Carla Vitorino; Maria T. Cruz. "Development of a new hydrogel for the prevention of allergic contact dermatitis". International Journal of Pharmaceutics 628 (2022): 122265-122265. http://dx.doi.org/10.1016/j.ijpharm.2022.122265.
    10.1016/j.ijpharm.2022.122265
  10. Marcelo D. Catarino; Ana Rita Circuncisão; Bruno Neves; Catarina Marçal; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso. "Impact of Gastrointestinal Digestion on the Anti-Inflammatory Properties of Phlorotannins from Himanthalia elongata". Antioxidants (2022): https://doi.org/10.3390/antiox11081518.
    10.3390/antiox11081518
  11. Sónia N. Pedro; Maria S. M. Mendes; Bruno M. Neves; Isabel Filipa Almeida; Paulo Costa; Inês Correia-Sá; Carla Vilela; et al. "Deep Eutectic Solvent Formulations and Alginate-Based Hydrogels as a New Partnership for the Transdermal Administration of Anti-Inflammatory Drugs". Pharmaceutics 14 4 (2022): 827-827. https://doi.org/10.3390/pharmaceutics14040827.
    10.3390/pharmaceutics14040827
  12. Pereira, Ana Catarina; De Pascale, Jessica; Resende, Rosa; Cardoso, Susana; Ferreira, Isabel; Neves, Bruno Miguel; Carrascal, Mylène A.; et al. "ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system". Cellular and Molecular Life Sciences 79 4 (2022): http://dx.doi.org/10.1007/s00018-022-04211-7.
    10.1007/s00018-022-04211-7
  13. Tatiana Maurício; Susana Aveiro; Sofia Guedes; Diana Lopes; Tânia Melo; Bruno M. Neves; Rosário Domingues; Pedro Domingues. "Multi-Omic Profiling of Macrophages Treated with Phospholipids Containing Omega-3 and Omega-6 Fatty Acids Reveals Complex Immunomodulatory Adaptations at Protein, Lipid and Metabolic Levels". International Journal of Molecular Sciences 23 4 (2022): 2139-2139. https://doi.org/10.3390/ijms23042139.
    10.3390/ijms23042139
  14. Zuzarte, Monica; Francisco, Vera; Neves, Bruno; Liberal, Joana; Cavaleiro, Carlos; Canhoto, Jorge; Salgueiro, Lígia; Cruz, Maria Teresa. "Lavandula viridis L´Hér. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade". Frontiers in Pharmacology 12 (2022): http://dx.doi.org/10.3389/fphar.2021.695911.
    10.3389/fphar.2021.695911
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  70. Francisco, V.; Figueirinha, A.; Neves, B.M.; García-Rodríguez, C.; Lopes, M.C.; Cruz, M.T.; Batista, M.T.. "Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guided assay using lipopolysaccharide-stimulated macrophages". Journal of Ethnopharmacology 133 2 (2011): 818-827. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651410773&partnerID=MN8TOARS.
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  71. Neves, Bruno; Rosa, Susana; Martins, Joao; Goncalo, Margarida; Lopes, Maria Celeste; Cruz, Maria Teresa. "An in vitro cell test for skin sensitizers prediction based on the analysis and integration of gene expression and signaling pathways activation". Journal of Investigative Dermatology 131 (2011): S91-S91. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294361300538&KeyUID=WOS:000294361300538.
  72. Francisco, V.; Neves, B.M.; Cruz, M.T.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.. "Effect of lipopolysaccharide, skin sensitizers and irritants on thioredoxin-1 expression in dendritic cells: Relevance of different signalling pathways". Archives of Dermatological Research 302 4 (2010): 271-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952180893&partnerID=MN8TOARS.
    10.1007/s00403-009-0993-z
  73. Neves, B.M.; Silvestre, R.; Resende, M.; Ouaissi, A.; Cunha, J.; Tavares, J.; Loureiro, I.; et al. "Activation of phosphatidylinositol 3-kinase/akt and impairment of nuclear factor-¿B: Molecular mechanisms behind the arrested maturation/activation state of leishmania infantum-infected dendritic cells". American Journal of Pathology 177 6 (2010): 2898-2911. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650195216&partnerID=MN8TOARS.
    10.2353/ajpath.2010.100367
  74. Neves, B.M.; Cruz, M.T.; Francisco, V.; Garcia-Rodriguez, C.; Silvestre, R.; Cordeiro-da-Silva, A.; Dinis, A.M.; et al. "Differential roles of PI3-Kinase, MAPKs and NF-¿B on the manipulation of dendritic cell Th1/Th2 cytokine/chemokine polarizing profile". Molecular Immunology 46 13 (2009): 2481-2492. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650397827&partnerID=MN8TOARS.
    10.1016/j.molimm.2009.05.021
  75. Neves, B.M.; Cruz, M.T.; Francisco, V.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.. "Differential modulation of CXCR4 and CD40 protein levels by skin sensitizers and irritants in the FSDC cell line". Toxicology Letters 177 1 (2008): 74-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-39549123001&partnerID=MN8TOARS.
    10.1016/j.toxlet.2007.12.006
  76. Cruz, M.T.; Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.. "Effect of skin sensitizers on inducible nitric oxide synthase expression and nitric oxide production in skin dendritic cells: Role of different immunosuppressive drugs". Immunopharmacology and Immunotoxicology 29 2 (2007): 225-241. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548553284&partnerID=MN8TOARS.
    10.1080/08923970701512304
Journal issue
  1. Neves, Bruno. "Dendritic Cell Vaccines". Pharmaceutics (2020): https://www.mdpi.com/journal/pharmaceutics/special_issues/dendritic_cell_vaccines#info.
    Published • Editor
  2. Neves, Bruno. "The Role of ER Stress and the UPR in Shaping Immunity". Frontiers in Immunology (2020): https://www.frontiersin.org/research-topics/9234/the-role-of-er-stress-and-the-upr-in-shaping-immunity.
    Published • Editor

Intellectual property

Patent
  1. Neves, Bruno. 2024. "TOPICAL COMPOSITION AND USES THEREOF".
  2. Neves, Bruno. 2023. "SMALL MOLECULES FOR USE IN PREVENTING AND/OR TREATMENT OF NEURODEGENERATIVE DISEASES".
  3. Neves, Bruno. 2012. "METHOD FOR DETERMINING SKIN SENSITISATION POTENTIAL". Portugal.
Provisional application for patent
  1. 2022. "COMPOSITIONS, METHODS AND USES OF EXTRACELLULAR VESICLES OF GIARDIA SPP".
  2. 2016. "FUNCTIONALIZED MATRICES TO DETECT THE HAPTENIZATION CAPACITY OF XENOBIOTICS".
  3. 2016. "Method for Determining Low Molecular Weight Respiratory Allergens (Provisional Patent Application no)".
  4. 2015. "AN IN SILICO AND IN VITRO INTEGRATIVE APPROACH TO ASSESS THE POTENCY OF CONTACT ALLERGENS".
  5. 2015. "Method for determining low molecular weight respiratory allergens".
    Disclosed

Other

Spin-off company
  1. 2011. Toxfinder Lda. In vitro predictive toxicology and pharmacological screening. http://toxfinder.pt/.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/04/03 The unfolded protein response in the modulation of macrophage functions 7th Workshop in Immunology
Universidade de Aveiro (Aveiro, Portugal)
2018/11/20 The unfolded protein response in the modulation of macrophage functions Signaling Afternoon, DCM-UA
Universidade de Aveiro (Aveiro, Portugal)
2016/09/16 Current status of dendritic cell-based tests for skin sensitizer identification 13th Congress of the European Society of Contact Dermatitis
European Society of Contact Dermatitis (Manchester, United Kingdom)
2015/05/21 Dendritic cell vaccines in the fight against cancer: current status and future perspectives III Workshop in Immunology
University of Aveiro (Aveiro, Portugal)
2013/11/30 Exosomes as possible biomarkers to support the diagnosis / prognosis of tumors and autoimmune pathologies XI Congresso de Análises Clínicas e Saúde Pública
Sociedade Portuguesa de BioAnalistas Clínicos (Figueira da Foz, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/09 - Current Development and Characterization of 3D breast cancer models
Co-supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2023/09 - Current Curricular internship at Evidenze
Supervisor
 Gestão da Investigação Clínica (Master)
Universidade de Aveiro, Portugal
2023/09 - Current Boosting anti-tumour immune response by creation of artificial immunogenic epitopes in cancer cells
Supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2022/10 - Current Estágio BluePharma
Supervisor
 Gestão da Investigação Clínica (Master)
Universidade de Aveiro, Portugal
2021/02/01 - Current Contribution of water-soluble organic matter and its structural components to the oxidative and immunomodulatory effects of inhalable fine urban air particles
Co-supervisor of Antoine Simões Almeida
Universidade de Aveiro Departamento de Química, Portugal
2021 - Current Cell-based therapies for regenerative medicine and cancer
Co-supervisor
 Biomedicina
Universidade de Aveiro, Portugal
2021 - Current Priming immune system through exercise training to improve cancer outcomes
Co-supervisor
 Atividade Física e Saúde (PhD)
Universidade do Porto, Portugal
2021 - Current Development of biopolymeric nanomachines for theranostic applications
Co-supervisor
 Nanociências e Nanotecnologia (PhD)
Universidade de Aveiro, Portugal
2021 - Current Development of a prophylactic dendritic cell-based vaccine: the only way to halt triple-negative breast cancer?
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade de Coimbra, Portugal
2018/06 - 2024/01/05 Development of a Medical Device for prevention of Skin Sensitization
Co-supervisor of Gonçalo Sousa Brites
 Ciências Farmacêuticas (PhD)
Universidade de Coimbra, Portugal
2020/11/10 - 2024/01 MiAL (MicroAlgae Lipids) – Exploitation of microalgae lipidome: a lipidomics strategy to bioprospect bioactive phytochemicals
Co-supervisor
Universidade de Aveiro Departamento de Química, Portugal
2022/09 - 2023/12/12 Assessment of the pro-inflammatory potential of inhalable airborne particles in indoor environments
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2022/09 - 2023/12/07 Dendritic cell-based vaccines: Evaluating their anti-tumoral efficacy
Supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2022/09 - 2023/11/30 In vitro study of the impact of dysbiosis-related metabolites on the activation of human monocytes
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2022/09 - 2023/11/28 Bioprospection Of Avocado By-Products As A Source Of Lipids With Anti-Inflammatory Potential Anti-Inflammatory Potential
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2021 - 2022/12/13 Nanoparticles as a way to Boost Cancer Immunogenicity: A Novel Approach to Potentiate Antitumor Immunotherapy
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2021 - 2022/12/07 Monitorização de estudos na Keypoint, Group Evidente
Co-supervisor
 Gestão da Investigação Clínica (Master)
Universidade de Aveiro, Portugal
2021 - 2022/11/29 Bioprospecting microalga Scenedesmus obliquus as a source of lipids with anti-inflammatory and antioxidant activity
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2021 - 2022/11/29 Bioprospecting Phaeodactylum tricornutum as a source of lipids with anti-inflammatory and anti-oxidant potential
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2020/09/01 - 2021/12/09 Flow cytometry immunological monitoring of patients with lung cancer undergoing immunotherapy
Co-supervisor of Patrícia Pilar Gomes Oliveira Maia
 Bioquímica Clínica (Master)
Universidade de Aveiro Departamento de Química, Portugal
2020/09/01 - 2021/11/30 Bioprospecting red seaweed Palmaria palmata as source of bioactive lipids
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro Departamento de Química, Portugal
2016 - 2021/04 Development of an in-vitro/in chemico platform to address chemical respiratory sensitization
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade de Coimbra, Portugal
2020/09/01 - 2021 Induced pluripotent stem cells (iPSC)-based cancer immunotherapy.
Co-supervisor
 Master in Molecular and Cell Biology (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2017/03 - 2021 Potentiation of dendritic cells phenotypic and functional characteristics for application in next-generation cancer immunotherapy
Supervisor of João Miguel Calmeiro Pereira
 Ciências Farmacêuticas (PhD)
Universidade de Coimbra, Portugal
2019 - 2019/12 Analysis of Monocyte-Derived Dendritic Cells Obtained Through Conventional vs. Fast Differentiation/Maturation Protocols
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2019 - 2019/12 Myeloid-derived suppressor cells (MDSC) analysis and their role in the Immunogram of cancer patients
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2018 - 2019 Skin sensitizers: new approaches for predicting toxicity and risk management
Co-supervisor
 Quimica Medicinal (Master)
Universidade de Coimbra Departamento de Química, Portugal
2017 - 2017/12 Assessment of the inflamatory potential of inhalable organic aerosols present in an urban atmosphere
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2016 - 2017/01 Pterospartum tridentatum: Estudo fitoquímico e avaliação das atividades biológicas dos seus compostos
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2015 - 2015/12 Estudo do microbioma no sémen em casos e controlos de infertilidade
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2014 - 2015/04 Estudo das variações da sequência do gene CYP21A2 em doentes com hiperplasia adrenal congénita
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2013 - 2014/07 O Stress do Retículo na Remodelação do Perfil Lipídico do Macrófago
Supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2013 - 2014 Contribution of ER stress to tumor immunosuppressive microenvironment
Supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2013 - 2013/12 Regulation of the adrenergic system in mice adipose tissue under obesity
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2012 - 2013/06 Role of ER stress in sensitization induced DC maturation/toxicity
Supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2012 - 2013/06 Deregulation of lipid homeostasis in Leishmania infantum -infected macrophages
Supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2012 - 2012/12 Avaliação da PCT e da PCR no Diagnóstico de Sépsis no Recém-Nascido
Co-supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/07/22 - Current 2nd Workshop on Sphingolipids in Health and Disease (2022/07/22 - 2022/07/23)
Workshop (Co-organisor)
 Universidade de Aveiro, Portugal
2022/04/06 - Current 10th Workshop in Lipidomics - Lipidomics in health & disease (2022/04/06 - 2022/04/06)
Workshop
 Universidade de Aveiro, Portugal
2023/03/29 - 2023/03/31 XLVIII Annual Meeting of the Portuguese Society for Immunology (2023/03/29 - 2023/03/31)
Meeting (Co-organisor)
 Sociedade Portuguesa de Imunologia, Portugal
2016/05/25 - 2016/05/25 IV Workshop in Immunology (2016/05/25 - 2016/05/25)
Workshop (Co-organisor)
 Universidade de Aveiro, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/12/15 Decifrando a interação entre as respostas anti virais dependentes da MAVS e da STING
President of the jury
 Rui Filipe Tavares Ferreira (Master)
Universidade de Aveiro, Portugal
2022/11/25 Buffy Coat Vs blood collection tube mononuclear cells: a functional characterization
President of the jury
 Sofia de Morais Borges (Master)
Universidade de Aveiro, Portugal
2022/11/21 A Novel Plant-Based Approach For The Treatment Of Pulmonary Arterial Hypertension
(Thesis) Main arguer
 Jorge Miguel Alves Silva. (PhD)
Universidade de Coimbra, Portugal
2022/10/28 Construction of tumor lines resistant to antiglycolytic agents to evaluate the effect on cell metabolism and viability
President of the jury
 Ana Catarina Gonçalves da Rocha (Master)
Universidade de Aveiro, Portugal
2022/10/12 Development of a Defined Approach for Respiratory Sensitization Hazard Assessment
(Thesis) Main arguer
 Rita Isabel Azambuja Lavrador (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/07/20 Contrast agents to map living tissue access to oxygen
(Thesis) Main arguer
 Maria Carolina Roseiro Ferrão Lopes (Other)
Universidade de Aveiro, Portugal
2022/02/09 Decoding the Crosstalk Between Dendritic Cells and Bladder Cancer – Associated Glycans: A Way to Identify Novel Immunotherapy Targets
(Thesis) Main arguer
 Andreia Rafaela Linhares Miranda (Master)
Universidade do Porto, Portugal
2021/12/06 Potentiation. of Dendritic Cell Phenotypic and Functional Characteristics for Application in Next-generation Cancer Immunotherapy
Supervisor
 João Miguel Calmeiro Pereira (PhD)
Universidade de Coimbra, Portugal
2021/12/04 Toxicological impact of three pharmacological therapeutics on human sperm
President of the jury
 Carolina Capucha Garcia (Master)
Universidade de Aveiro, Portugal
2021/11/23 UNRAVELING THE AXONAL PROTEOME OF HIPPOCAMPAL NEURONS
President of the jury
 José João Macedo Felgueiras (Master)
Universidade de Aveiro, Portugal
2021/11/17 Molecular mechanisms of macrophages adaptation when supplemented with phospholipids with Omega-3 and Omega-6 fatty acids
(Thesis) Main arguer
 Tatiana Sofia Cardoso Maurício (Master)
Universidade de Aveiro, Portugal
2021/07/27 Genotype-phenotype characterization of patients with Autism Spectrum Disorder – Analysis of copy number variation
President of the jury
 Tatiana da Cruz Almeida (Master)
Universidade de Aveiro, Portugal
2021/02/25 Analysis of Fig4 interfered cells and its role on the endocytic pathway
(Thesis) Main arguer
 Tiago Pinto Vieira (Master)
Universidade de Aveiro, Portugal
2021/01/21 Plasma phospholipidome analysis reveals a different profile between children with phenylketonuria and healthy children
(Thesis) Main arguer
 Inês Maria dos Santos Guerra (Master)
Universidade de Aveiro Departamento de Química, Portugal
2021/01/05 Dissecting the mechanisms governing skin wound healing induced by an UCB-derived product
(Thesis) Arguer
 Sílvia Maria do Couto Rodrigues (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2020/12/10 Dendritic cell-based cancer immunotherapy the role of DC-NK crosstalk
(Thesis) Main arguer
 Daniel Alexandre Bento Ferreira (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/12/09 Characterization of a-GlcCer reactive iNKT cells and MAIT cells of Gaucher disease patients
(Thesis) Main arguer
 RAFAEL CARNEIRO LOPES (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/12/03 Study of VTN, PLG and other coagulation genes in atypical Hemolytic Uremic Syndrome (aHUS) Jéssica Filipa Pires Malva (Master)
Universidade de Aveiro Departamento de Química, Portugal
2020/10/26 Development of Biomimetic Pancreatic Cancer 3D in vitro Models for Preclinical Drug Screening
(Thesis) Main arguer
 MARIA VINHAS MONTEIRO (Master)
Universidade de Aveiro, Portugal
2019/12/11 Testing the combinatory use of PARPI and RPA inhibitors in breast cancer cell lines
President of the jury
 Tatiana Natália Tavares Magro (Master)
Universidade de Aveiro, Portugal
2019/09 The Macrophage-iNKT axis: macrophage survival and activation are modulated upon invariant NKT interaction
(Thesis) Main arguer
 José Pedro Pereira Loureiro (Master)
Universidade de Coimbra, Portugal
2018/12/10 The interplay between human cytomegalovirus and peroxisomes: metabolism and membrane association with the endoplasmic reticulum
President of the jury
 Beatriz Soares Carneiro da Silva (Master)
Universidade de Aveiro, Portugal
2018 Flavonoid-mediated modulation of human macrophages phospholipidome: an LC-MS lipidomics study
(Thesis) Main arguer
 Tiago Alexandre Teixeira de Sousa Conde (Master)
Universidade de Aveiro, Portugal
2016/12 Assessment of potential anti-tumour agents for photodynamic therapy
(Thesis) Main arguer
 Inês Mendes Sardo (Master)
Universidade de Aveiro, Portugal
2016/09 The interaction of Giardia Lamblia with macrophages cells: the action of parasite protéases on iNOS, COX-2 and p65RelA inflammatory proteins
(Thesis) Main arguer
 Ágata Filipa Bandeira Lourenço (Master)
Universidade de Coimbra, Portugal
2015/09 Impact of chemotherapeutic drugs in NK-mediated killing by over expression of death receptors on cancer cells
(Thesis) Main arguer
 Ana Filipa Fernandes Gomes (Master)
Universidade de Coimbra, Portugal
2014/07 Studies of the interaction between heme oxygenase-1 and human HBP
(Thesis) Main arguer
 Iga Karolina Jodlowska (Master)
Universidade de Aveiro, Portugal
2014/07 Analysis of human genomes of Portuguese individuals
President of the jury
 Ana Carolina Marianito Serrano (Master)
Universidade de Aveiro, Portugal
2014/06 CD5, A Molecular Switch Regulating Signaling at the Surface of T Cells
(Thesis) Main arguer
 Ana Rita Santos (Master)
Universidade de Aveiro, Portugal
2014/06 Novos biomateriais baseados em celulose bacteriana para aplicações biomédicas
President of the jury
 Bruno Filipe Afonso Valente (Master)
Universidade de Aveiro, Portugal
2013/07 Drug discovery of new anti-inflammatory phytochemicals using in vitro guided assays: The case study of Cymbopogon citratus
(Thesis) Arguer
 Vera Lúcia Gomes Francisco (PhD)
Universidade de Coimbra, Portugal
2013/07 Lipidomic and proteomic in cancer-related skeletal muscle wasting
(Thesis) Main arguer
 Diana Sofia Ribeiro Duarte Antunes (Master)
Universidade de Aveiro, Portugal
2013/07 Estudo da Função Renal em Pacientes Com Diabetes Mellitus
President of the jury
 Andrea Janeth da Silva da Silva (Master)
Universidade de Aveiro, Portugal
2013/07 Complicações das estratégias de Reinfusão em Cirurgias Ortopédicas Daniela Sofia Bandeira Gomes Duarte (Master)
Universidade de Aveiro, Portugal
2012/12 Análise da histona H2A tipo 2-C na diferenciação celular e no cancro da mama
(Thesis) Main arguer
 Celestina Gomes Lopes (Master)
Universidade de Aveiro, Portugal
2012/07 Perfil lipídico de Cérebro e Coração de Ratinhos com Stress Crónico
President of the jury
 Renata Alexandra Boaventura Faria (Master)
Universidade de Aveiro, Portugal

Committee member

Activity description
Role 		Institution / Organization
2022/07/01 - Current Member of the Pedagogical Quality and Evaluation Council of the Department of Medical Sciences of the University of Aveiro.
Member
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022/06/01 - Current Member of the Board of the Department of Medical Sciences of the University of Aveiro.
Member
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018/10/01 - Current Director of the Biomedical Sciences degree at Department of Medical Sciences, University of Aveiro
Director
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018/06/01 - Current Member of the Scientific Council of the Institute of Biomedicine (iBiMED) of the University of Aveiro
Member
 Universidade de Aveiro Instituto de Biomedicina, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020/12 - Current Evaluation of National projects for the National Innovation Agency (ANI)
Evaluator
 Universidade de Aveiro, Portugal Agência Nacional de Inovação SA
2021 - 2021 Reviewer of projects submited to the Dutch Cancer Society (KWF)
Evaluator
 KWF Kankerbestrijding, Netherlands KWF Kankerbestrijding
2017 - 2017 Member of the evaluation panel of scientific projects in the areas of Cellular and Molecular Biology and Immunology
Evaluator
 National Center of Science and Technology Evaluation Ministry of Education and Science Republic of Kazakhstan, Kazakhstan

Journal scientific committee

Journal title (ISSN) Publisher
2021 - Current Translational Oncology (1936-5233) Elsevier
2020 - Current Molecules (1420-3049) MDPI
2020 - Current Molecular Therapy: Methods & Clinical Development (23290501) Elsevier
2020 - Current Journal of Clinical Medicine (2077-0383) MDPI
2020 - Current Journal of European Academy of Dermatology Venereology (1468-3083) Wiley
2016 - Current European Journal of Pharmaceutical Sciences (0928-0987) Elsevier
2016 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2014 - Current Drug Design Development and Therapy (1177-8881) Dove Medical Press
2012 - Current International Journal of Nanomedicine (1178-2013) Dove Medical Press

Mentoring / Tutoring

Topic Student name
2014/05/12 - 2015/07/31 Development of an in vitro cell test for skin sensitizer identification Ana Cristina R. Silva
Distinctions

Award

2021 Award for the best poster presentation - VI Jornadas da Bioquímica
2018 Best Poster Award
European Society of Contact Dermatitis, Germany
2018 ImmunoTools Special Award
ImmunoTools , Germany
2014 Entrepreneurship award: Bolsa de Ignição INOV.Capital
Universidade de Coimbra, Portugal
2013 Award for innovation and entrepreneurship (First prize)
Biocant and Caixa de Crédito Agrícola, Portugal
2012 Regional Business Ideas Competition RIERC 2012 (First Prize)
Rede de Incubadoras de Empresas da Região Centro, Portugal
2011 Idea to Product Portugal Competition (3rd prize)
COTEC Portugal, Portugal
2010 Entrepreneurship award: Bolsa de Ignição INOV.C 2010 (First Prize)
Universidade de Coimbra, Portugal
2009 Prix de Recherche Sientifique Lierac
Alès Groupe, France
2008 Best Poster Award
European Society of Contact Dermatitis, Germany