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Professor Auxiliar e investigadora do iMed no(a) Universidade de Lisboa Faculdade de Farmácia (até 2022/ 23). Avaliação do serviço docente: Excelente. Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Ciências da Saúde. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Farmacotecnia Avançada; Ciclodextrinas; Lipossomas Deformáveis; Nanopartículas; Via dérmica e transdérmica; Antioxidantes; Doenças cutâneas; Em 2022: pedido de mobilidade intercarreiras para o INFARMED, I.P. na Unidade de Inspeção e Licenciamento, incluindo Gestão de Alertas de Defeitos de Qualidade em colaboração com outras Direções.
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Identification

Personal identification

Full name
Andreia Patrícia Henriques Ascenso

Citation names

  • ascenso, andreia

Author identifiers

Ciência ID
761B-404D-2C83
ORCID iD
0000-0002-8727-0614

Email addresses

  • andreia.ascenso@infarmed.pt (Professional)

Telephones

Mobile phone
  • 926984823 (Personal)

Addresses

  • Faculdade de Farmácia, Avenida Professor Gama Pinto , 1649-003, Lisboa , Lisboa, Portugal (Professional)
  • Infarmed – Autoridade Nacional do Medicamento e Produtos de Saúde, I.P., Edifício Tomé Pires, Av. do Brasil 53 Pavilhão 21A, Pavilhão 24, , 1749-004, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Health Policy and Services
  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Other Medical Sciences
  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2013/07/11
Concluded
 tecnologia farmacêutica (Doutoramento)
Major in Farmacotecnia Avançada
Universidade de Lisboa Faculdade de Farmácia, Portugal
"“Carrier mediated Dermal Delivery for Prevention or Treatment of Skin Disorders” " (THESIS/DISSERTATION)
 summa cum laude
2008
Concluded
 Curso de Farmacotecnia Avançada (Mestrado)
Universidade de Lisboa, Portugal
 Muito Bom
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2013/09/01 - Current Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal

Other Careers

Category
Host institution 		Employer
2022/04/01 - Current Técnico Superior (Técnico Superior) Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP Centro de Documentação Técnica e Científica, Portugal
Projects

Contract

Designation Funders
2019/01 - Current Terapias baseadas em fármacos serotoninérgicos para diminuir o impacto da psoríase moderada a grave: da investigação académica à indústria
LISBOA-01-0145-FEDER-030198
LISBOA-01-0145-FEDER-030198
Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01 - Current 3SLYCO - Abordagem Sustentável, Segura e eScalável para a valorização do licopeno: conduzindo o conhecimento para uma interface academia-indústria para o tratamento tópico da inflamação
LISBOA-01-0145-FEDER-030197
LISBOA-01-0145-FEDER-030197
Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Centro Interuniversitário de História das Ciências e da Tecnologia
Ongoing
2016/09/01 - Current Desenvolvimento de uma nova estratégia não invasiva para o tratamento da SIDA: T20 veiculado em Transfersomas para libertação transdérmica
PGG/006/2016
Researcher

Other

Designation Funders
2018/12/01 - Current Desenvolvimento e caraterizaçao de uma formulação avançada de insulina para regeneraçao cutanea de queimaduras
NA
Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal
Ongoing
2016/07/01 - Current Effects of water depleted from heavy isotopes of oxygen and hydrogen on physical properties and penetration of plant-derived polyphenols through cutaneous barrier
NA
Researcher
Concluded
Outputs

Publications

Book chapter
  1. ascenso, andreia. "Nanoemulsions for cosmetic products". 2020.
    10.1016/b978-0-12-822286-7.00004-8
Edited book
  1. ascenso, andreia. Carrier Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. 2017.
Journal article
  1. Laranjeira, Tânia; Costa, Ana; Faria-Silva, Catarina; Ribeiro, Daniela; de Oliveira, José Miguel P. Ferreira; Simões, Sandra; Ascenso, Andreia. "Sustainable Valorization of Tomato By-Products to Obtain Bioac-Tive Compounds: Their Potential in Inflammation and Cancer Management". Molecules 27 5 (2022): 1701. http://dx.doi.org/10.3390/molecules27051701.
    10.3390/molecules27051701
  2. Rita F. Cunha; Sandra Simões; Manuela Carvalheiro; José M. Azevedo Pereira; Quirina Costa; Andreia Ascenso. "Novel Antiretroviral Therapeutic Strategies for HIV". Molecules 26 17 (2021): 5305-5305. https://doi.org/10.3390/molecules26175305.
    10.3390/molecules26175305
  3. "Nasal Spray Formulations Based on Combined Hyalurosomes and Glycerosomes Loading Zingiber officinalis Extract as Green and Natural Strategy for the Treatment of Rhinitis and Rhinosinusitis". Antioxidants 10 7 (2021): 1109-1109. http://dx.doi.org/10.3390/antiox10071109.
    10.3390/antiox10071109
  4. ascenso, andreia. "The Brain–Skin Connection and the Pathogenesis of Psoriasis: A Review with a Focus on the Serotonergic System". Cells (2020): http://dx.doi.org/10.3390/cells9040796.
    10.3390/cells9040796
  5. ascenso, andreia. "Lycopene in human health". LWT (2020): http://dx.doi.org/10.1016/j.lwt.2020.109323.
    10.1016/j.lwt.2020.109323
  6. ascenso, andreia. "Current and Future Therapies for Psoriasis with a Focus on Serotonergic Drugs". Molecular Neurobiology (2020): http://dx.doi.org/10.1007/s12035-020-01889-3.
    10.1007/s12035-020-01889-3
  7. ascenso, andreia. "Therapeutic Advances in Wound Healing". Journal of Dermatological Treatment (2020): http://dx.doi.org/10.1080/09546634.2020.1730296.
    10.1080/09546634.2020.1730296
  8. ascenso, andreia. "Nanomaterials in Nanomaterials in wound healing: From material sciences to wound healing applications". Nano Select (2020): 1-18. https://onlinelibrary.wiley.com/doi/10.1002/nano.202000055.
    Open access • Published
  9. ascenso, andreia. "Cytotoxic effect of the serotonergic drug 1-(1-Naphthyl)piperazine against melanoma cells.". Toxicology in vitro : an international journal published in association with BIBRA (2018): https://doi.org/10.1016/j.tiv.2017.11.011.
    10.1016/j.tiv.2017.11.011
  10. ascenso, andreia. "Development and characterization of new and scalable topical formulations containing N-acetyl-d-glucosamine-loaded solid lipid nanoparticles.". Drug development and industrial pharmacy (2017): http://europepmc.org/abstract/med/28581831.
    10.1080/03639045.2017.1339083
  11. ascenso, andreia. "Evaluation of critical parameters for in vitro skin permeation and penetration studies using animal skin models.". European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2017): http://europepmc.org/abstract/med/28951120.
    10.1016/j.ejps.2017.09.034
  12. Joana Marto; Catarina Vitor; Ana Guerreiro; Cristiana Severino; Carla Eleutério; Andreia Ascenso; Sandra Simões. "Ethosomes for enhanced skin delivery of griseofulvin". Colloids and Surfaces B: Biointerfaces 146 (2016): 616-623. http://dx.doi.org/10.1016/j.colsurfb.2016.07.021.
    10.1016/j.colsurfb.2016.07.021
  13. Marto J; Ascenso A; Simoes S; Almeida AJ; Ribeiro HM. "Pickering emulsions: challenges and opportunities in topical delivery.". (2016): http://europepmc.org/abstract/med/27108850.
    10.1080/17425247.2016.1182489
  14. Ana Catarina Menezes; Patrícia Mazureki Campos; Carla Euletério; Sandra Simões; Fabíola Silva Garcia Praça; Maria Vitória Lopes Badra Bentley; Andreia Ascenso. "Development and characterization of novel 1-(1-Naphthyl)piperazine-loaded lipid vesicles for prevention of UV-induced skin inflammation". European Journal of Pharmaceutics and Biopharmaceutics 104 (2016): 101-109. http://dx.doi.org/10.1016/j.ejpb.2016.04.023.
    10.1016/j.ejpb.2016.04.023
  15. Marto J; Ascenso A; Gonçalves LM; Gouveia LF; Manteigas P; Pinto P; Oliveira E; Almeida AJ; Ribeiro HM. "Melatonin-based pickering emulsion for skin's photoprotection.". (2016): http://europepmc.org/abstract/med/26755411.
    10.3109/10717544.2015.1128496
  16. Andreia Ascenso; Tiago Pedrosa; Sónia Pinho; Francisco Pinho; José Miguel P. Ferreira de Oliveira; Helena Cabral Marques; Helena Oliveira; Sandra Simões; Conceição Santos. "The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes". Oxidative Medicine and Cellular Longevity 2016 (2016): 1-15. http://dx.doi.org/10.1155/2016/8214631.
    10.1155/2016/8214631
  17. Menezes, Ana Catarina; Oliveira, José Miguel; Carvalheiro, Manuela; Oliveira, Helena; Ascenso, Andreia. "Agonistas e antagonistas dos recetores 5-HT1A e 5-HT2A no tratamento do cancro da pele". (2016): https://proa.ua.pt/index.php/captar/article/view/12737.
    10.34624/captar.v6i1.12737
  18. Ascenso A; Raposo S; Batista C; Cardoso P; Mendes T; Praça FG; Bentley MV; Simões S. "Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes.". (2015): http://europepmc.org/abstract/med/26425085.
    10.2147/IJN.S86186
  19. ascenso, andreia. "Lycopene for Chemoprevention of Photocarcinogenesis". Experimental Dermatology (2014): http://www.ncbi.nlm.nih.gov/pubmed/?term=Lycopene+for+Chemoprevention+of+Photocarcinogenesis..
  20. ascenso, andreia. "In Vitro and In Vivo Topical Delivery Studies of Tretinoin - Loaded Ultradeformable Vesicles". European Journal of Pharmaceutics and Biopharmaceutics. (2014): http://www.ncbi.nlm.nih.gov/pubmed/?term=In+Vitro+and+In+Vivo+Topical+Delivery+Studies+of+Tretinoin+-+Loaded+Ultradeformable+Vesicles.
  21. ascenso, andreia. "Is Tretinoin still a Key Agent for Photoaging Management?". Mini-Review in Medicinal Chemistry (2014): http://www.ncbi.nlm.nih.gov/pubmed/25141855.
  22. Ascenso, A.; Pinho, S.; Eleutério, C.; Praça, F.G.; Bentley, M.V.L.B.; Oliveira, H.; Santos, C.; Silva, O.; Simões, S.. "Lycopene from tomatoes: Vesicular nanocarrier formulations for dermal delivery". Journal of Agricultural and Food Chemistry 61 30 (2013): 7284-7293. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881080237&partnerID=MN8TOARS.
    10.1021/jf401368w
  23. Ascenso, A.; Cruz, M.; Euletério, C.; Carvalho, F.A.; Santos, N.C.; Marques, H.C.; Simões, S.. "Novel tretinoin formulations: A drug-in-cyclodextrin-in-liposome approach". Journal of Liposome Research 23 3 (2013): 211-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880463944&partnerID=MN8TOARS.
    10.3109/08982104.2013.788026
  24. Ascenso, A.; Vultos, F.; Ferrinho, D.; Salgado, A.; Filho, S.G.; Ferrari, V.; Simões, S.; Marques, H.C.. "Effect of tretinoin inclusion in dimethyl-beta-cyclodextrins on release rate from a hydrogel formulation". Journal of Inclusion Phenomena and Macrocyclic Chemistry 73 1-4 (2012): 459-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862621735&partnerID=MN8TOARS.
    10.1007/s10847-011-0002-y
  25. Ascenso, A.; Ribeiro, H.M.; Marques, H.C.; Simões, S.. "Topical delivery of antioxidants". Current Drug Delivery 8 6 (2011): 640-660. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054119415&partnerID=MN8TOARS.
    10.2174/156720111797635487
  26. Ascenso, A.; Guedes, R.; Bernardino, R.; Diogo, H.; Carvalho, F.A.; Santos, N.C.; Silva, A.M.; Marques, H.C.. "Complexation and full characterization of the tretinoin and dimethyl-ß-cyclodextrin complex.". AAPS PharmSciTech 12 2 (2011): 553-563. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861168025&partnerID=MN8TOARS.
  27. Ascenso, A.; Duarte, A.; Silva, A.; Salgado, A.; Marques, H.C.. "Formulation studies on a topical gel of tretinoin-dimethyl-beta- cyclodextrin complex". Journal of Inclusion Phenomena and Macrocyclic Chemistry 69 3-4 (2011): 339-343. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955949111&partnerID=MN8TOARS.
    10.1007/s10847-010-9745-0
  28. Ascenso, A.; Marques, H.C.. "Acne in the adult". Mini-Reviews in Medicinal Chemistry 9 1 (2009): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-62749120323&partnerID=MN8TOARS.
    10.2174/138955709787001730
Newspaper article
  1. ascenso, andreia; simões, sandra. "Feeding the skin: A new trend in food and cosmetics convergence", Trends in Food Science & Technology , 2020, https://www.sciencedirect.com/science/article/pii/S0924224419305035.
    10.1016/j.tifs.2019.11.015
Thesis / Dissertation
  1. Cunha, Rita Pinto Baptista Ferreira da. "Novel Antiretroviral Therapeutic Strategies for HIV". Master, 2019. http://hdl.handle.net/10451/43463.
  2. Oliveira, André Filipe Ferreira de. "Avanços Tecnológicos na Regeneração Cutânea". Master, 2019. http://hdl.handle.net/10451/43333.
  3. Andrade, Sara Catarina Henriques. "The influence of different nanocarriers on skin’s biophysical parameters". Master, 2017. http://hdl.handle.net/10451/36158.
  4. Rosa, Daniela Filipa Firmino. "Bringing the biorefinery concept to the health-care facilities: use of industrial by-products against multi-drug resistant bacteria". Master, 2016. http://hdl.handle.net/10362/82972.
  5. Manteigas, Patrícia Alexandra Rodrigues. "Melatonin, a "guardian" of the genome and cellular integrity for prevention of photocarcinogenesis". Master, 2015. http://hdl.handle.net/10451/27026.
  6. Mendes, Tiago José Rodrigues. "Lipid vesicles : evolution from first generation". Master, 2015. http://hdl.handle.net/10451/27038.
  7. Lana, Joice Naiara Alves. "Neurocosmetics, injectable and laser treatments for skin aging management". Master, 2015. http://hdl.handle.net/10451/27010.
  8. Menezes, Ana Catarina da Silva Fernandes Saraiva de. "Management of skin cancer by agonists of 5-HT1A and antagonists of 5-HT2A receptors". Master, 2015. http://hdl.handle.net/10451/20805.
  9. Batista, Cátia Sofia Martins. "Modelos animais usados para a abordagem terapêutica do cancro da pele". Master, 2015. http://hdl.handle.net/10451/26940.
  10. Valente, Marta Pereira. "O ABC da psoríase". Master, 2014. http://hdl.handle.net/10451/26917.
  11. Tomé, Ana Margarida Narciso. "O Licopeno na Prevenção do Envelhecimento Cutâneo : Ficção ou Realidade?". Master, 2014. http://hdl.handle.net/10451/25742.
  12. Andrade, Mariana de Braula Reis Rebelo de. "Dermocosmetologia na pele xerótica". Master, 2014. http://hdl.handle.net/10451/26751.
  13. Contente, Filipa Pereira Portela Dias. "Abordagem farmacêutica na prevenção e tratamento das principais dermatites da pele infantil". Master, 2014. http://hdl.handle.net/10451/25637.
  14. Ascenso, Andreia Patrícia Henriques, 1979-. "Carrier-mediated dermal delivery for prevention or treatment of skin disorders". PhD, 2013. http://hdl.handle.net/10451/8914.
  15. Ascenso, Andreia Patrícia Henriques, 1979-. "Formulação de um gel de complexo tretinoína dimetil-beta-ciclodextrina para aplicação tópica". Master, 2008. http://sibul.reitoria.ul.pt/F/?func=item-global&doc_library=ULB01&type=03&doc_number=000540409.

Other

Other output
  1. Agonistas e antagonistas dos recetores 5-HT1A e 5-HT2A no tratamento do cancro da pele. Resumo. 2016. Menezes, Ana Catarina; Faculdade de Farmácia da Universidade de Lisboa; Oliveira, José Miguel; CESAM, Departamento de Biologia, Universidade de Aveiro; Carvalheiro, Manuela; Grupo de Nanomedicina e Sistemas de Entrega de Fármacos, iMed.UL; Oliveira, Helena; CESAM, Departamento de Biologia, Universidade de Aveiro; Ascenso, Andreia; Grupo de Nanomedicina e Sistemas de Entrega de Fármacos, iMed.UL. http://revistas.ua.pt/index.php/captar/article/view/3615.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/03/23 Management of skin cancer by agonists of 5-HT1A and antagonists of 5-HT2A receptors International Conference on Health & Medical Research
2019 Lipid nanotechnology-based formulations containing Lycopene extract: safety and biological activity assessment Natural Products in Drug Discovery and Human Health (NatProdDDH)
Universidade Lusofona, Lisboa
2019 Lycopene extract incorporation in microemulsions for skin bioavailability enhancement. International Conference on Carotenoid Research and Applications in Agro-Food and Health
(Cyprus)
2016 Bringing the biorefinery concept to the health-care facilities: use of industrial by-products against multi-drug resistant bacteria Jornadas intercalares de Mestrados da FCT-UNL
2015 Development, Characterization and Skin Delivery Studies of Related Ultradeformable Vesicles: Transfersomes, Ethosomes and Transethosomes: Applications for Prevention or Treatment of Skin Disorders 5th International Conference on Clinical & Experimental Dermatology
2015 “Desenvolvimento de Formulações Tópicas- Ensaio de Cedência” Inovação pedagógica no ensino superior: e-learning e tecnologias digitais:
reitoria, UL
2013 Carrier Mediated Dermal Delivery for Prevention or Treatment of Skin Disorders Nanotek
2013 Evaluation of reactive oxygen species production and mitochondrial membrane potential on adherent cell lines using flow cytometry XIII Congresso da Sociedade Ibérica de Citómetria
UA
2012 Ensaios in vitro com Fitocompostos workshop de Biotecnologia
UA
2012 The Potential Role of Lycopene in Human Health iMed NanoDDS Group Meeting
FFUL
2012 Incorporation of Tretinoin in Dimethyl-ß-Cyclodextrin for Topical Delivery: a drug-in-cyclodextrin-in-liposome approach postgraduated iMed Students Meetings
FFUL
2009 Tretinoin Cyclodextrin Complexes for Topical Administration for the Treatment of Acne European Cyclodextrin Society

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2015 - 2016 Bringing the biorefinery to the healthcare facilities: the use of industrial by-products against multi-drug resistance bacteria
Co-supervisor
2014 - 2015 Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors
Supervisor

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022 - Current Formações e Atividades desempenhadas no INFARMED, IP- Anexo I
2020 - Current Ensino à distância: Formação da Plataforma ZOOM; Curso online site EAD com Wordpress e Sensei Webinar Elearning, Leonel Morgado, da Universidade Aberta, SNESup
2020 - Current Plataforma Network / find new collaborators: linqbio.com; COST Actions

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021 “Design, characterization and efficacy evaluation of natural nasal spray based on phospholipid vesicles loading plant-extracts" Eleonora Casula (PhD)
2014 Efeitos Citotóxicos da Hesperetina e antineoplásicos em células U2OS Laura Coutinho (Master)

Committee member

Activity description
Role 		Institution / Organization
2021 - 2021 1º Symposium on Advanced Technologies for Drug Delivery
2021 - 2021 1º Skin Summit

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019 - Current Nova UC: Profissão Farmacêutica (regência partilhada) (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - Current curso elearning: Curso pós graduado de atualização ou de aperfeiçoamento em produtos cosméticos – Cosmetologia Avançada (Módulo 4- vesículas lipídicas (Outros) Universidade de Lisboa Faculdade de Farmácia, Portugal
2006 - Current Tecnologia Farmacêutica (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2021 - Current Conselheira Científica do Prémio de Inovação e Ciência 2021 FFUL na área da Inovação Tecnológica.
2017 - 2017 Organização/ Comissão científica do Congresso EuroCD2017

Journal scientific committee

Journal title (ISSN) Publisher
2019 - Current Medcave Journal of Clinical Toxicology Editorial Member
2020 - 2021 Molecules MDPI

Other jury / evaluation

Activity description Institution / Organization
2008 - Current Avaliação das teses de dissertação do MICF e de cadeiras de projeto de carater cientifico
Distinctions

Award

2016 Gilead GÉNESE
2014 Poster
2014 Poster
2013 Poster

Title

2013 Mestrado e Doutoramento em Tecnologia Farmacêutica