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Professional with strong biomedical and scientific background in biomedical sciences and extensive international experience (USA, UK, Portugal). Passionate about science and how it impacts people’s lives, particularly in the field of healthcare. Professional Experience Present Freelance Medical Writer at Prime Focus (CRO) and Scite (Science Communication) • Experience in writing study reports, primary research articles and reviews. • Editing, proofreading, literature searches, translation. Part-time Assistant to the President and Scientific Advisor at Evita – Hereditary Cancer, an NGO supporting patients and healthy carriers of hereditary cancer mutations. • Participation in several events aimed at increasing scientific literacy in the field of cancer among the general public. • Patient advocacy among stakeholders and powers that be by participation in advisory boards, scientific meetings, patient groups and meetings with national health authorities. • Managing outreach through online activities on our webpage and social media. 2007-2018 Various Research Scientist positions in the United Kingdom at King’s College London and at University College London and Portugal (IMM, Fac Medicina Lisboa) • In depth scientific knowledge of the biomedical field, in particular the fields of birth defects, neuroscience, angiogenesis (both in physiological and oncogenic contexts) and cardiovascular disease. • Communication skills: presentation of scientific data at international scientific meetings, as well as broad teaching experience. Experience in communicating with clinicians and discussing medically relevant research projects. • Excellent writing skills demonstrated by eleven scientific publications in highimpact international peer-reviewed journals (https://orcid.org/0000-0002-8683- 4991), and several grant applications. • Supervision of undergraduate and postgraduate research students’ projects, including mentoring and teaching scientific concepts.
Identification

Personal identification

Full name
Ana Isabel Cosme Nunes Rolo

Citation names

  • Rolo, Ana

Author identifiers

Ciência ID
7512-8552-BFBE
ORCID iD
0000-0002-8683-4991

Telephones

Mobile phone
  • 962441986 (Personal)

Addresses

  • A. João Crisóstomo 4, 7ºDto, 1000-178, Lisboa, Lisboa, Portugal (Personal)

Knowledge fields

  • Natural sciences - Biological Sciences - Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Advanced (C1) Advanced (C1) Elementary (A2) Advanced (C1)
French Elementary (A2) Elementary (A2) Beginner (A1) Elementary (A2)
Education
Degree Classification
2007
Concluded
PhD in Biology (Doutoramento)
University of Virginia, United States
"Myosin II in early Xenopus morphogenesis" (THESIS/DISSERTATION)
n/a
2000
Concluded
Mestrado em Biologia do Desenvolvimento (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
"Patterning of the primary neurons in Xenopus laevis" (THESIS/DISSERTATION)
Bom
1998
Concluded
Licenciatura em Biologia (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"n/a" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2018/01/06 - 2018/12/31 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2017/04/01 - 2018/04/30 Postdoc (Research) King's College London, United Kingdom
King's College London, United Kingdom
2010/01/01 - 2017/03/31 Postdoc (Research) University College London Institute of Child Health, United Kingdom
University College London Institute of Child Health, United Kingdom
2007/03/01 - 2009/12/31 Postdoc (Research) University College London Division of Biosciences, United Kingdom
University College London Division of Biosciences, United Kingdom

Other Careers

Category
Host institution
Employer
2019/10/15 - Current Encarregado Geral Operacional (Assistente Operacional) EVITA - Associação de Apoio a Portadores de Alterações no Genes Relacionados com Cancro Hereditário, Portugal
EVITA - Associação de Apoio a Portadores de Alterações no Genes Relacionados com Cancro Hereditário, Portugal
Outputs

Publications

Journal article
  1. Nikolopoulou, E.; Hirst, C.S.; Galea, G.; Venturini, C.; Moulding, D.; Marshall, A.R.; Rolo, A.; et al. "Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2". Nature Communications 10 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85066953271&partnerID=MN8TOARS.
    10.1038/s41467-019-10164-6
  2. Rolo, A.; Galea, G.L.; Savery, D.; Greene, N.D.E.; Copp, A.J.. "Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects". Disease models & mechanisms 12 11 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85075088792&partnerID=MN8TOARS.
    10.1242/dmm.040683
  3. Rolo, A.; Escuin, S.; Greene, N.D.E.; Copp, A.J.. "Rho GTPases in mammalian spinal neural tube closure". Small GTPases 9 4 (2018): 283-289. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048247234&partnerID=MN8TOARS.
    10.1080/21541248.2016.1235388
  4. De Castro, S.C.P.; Gustavsson, P.; Marshall, A.R.; Gordon, W.M.; Galea, G.; Nikolopoulou, E.; Savery, D.; et al. "Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice". Human molecular genetics 27 24 (2018): 4218-4230. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058555216&partnerID=MN8TOARS.
    10.1093/hmg/ddy313
  5. De Castro, S.C.P.; Hirst, C.S.; Savery, D.; Rolo, A.; Lickert, H.; Andersen, B.; Copp, A.J.; Greene, N.D.E.. "Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues". Developmental Biology (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041623278&partnerID=MN8TOARS.
    10.1016/j.ydbio.2018.01.016
  6. Nikolopoulou, E.; Galea, G.L.; Rolo, A.; Greene, N.D.E.; Copp, A.J.. "Neural tube closure: Cellular, molecular and biomechanical mechanisms". Development (Cambridge) 144 4 (2017): 552-566. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012975343&partnerID=MN8TOARS.
    10.1242/dev.145904
  7. Galea, G.L.; Cho, Y.-J.; Galea, G.; Molè, M.A.; Rolo, A.; Savery, D.; Moulding, D.; et al. "Biomechanical coupling facilitates spinal neural tube closure in mouse embryos". Proceedings of the National Academy of Sciences of the United States of America 114 26 (2017): E5177-E5186. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021416744&partnerID=MN8TOARS.
    10.1073/pnas.1700934114
  8. Rolo A; Escuin S; Greene ND; Copp AJ. "Rho GTPases in mammalian spinal neural tube closure.". (2016): http://europepmc.org/abstract/med/27768516.
  9. Rolo, A.; Savery, D.; Escuin, S.; de Castro, S.C.; Armer, H.E.J.; Munro, P.M.G.; Molè, M.A.; Greene, N.D.E.; Copp, A.J.. "Regulation of cell protrusions by small GTPases during fusion of the neural folds". eLife 5 APRIL2016 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84968820423&partnerID=MN8TOARS.
    10.7554/eLife.13273
  10. Pai, Y.-J.; Abdullah, N.; Mohd.-Zin, S.W.; Mohammed, R.S.; Rolo, A.; Greene, N.D.; Abdul-Aziz, N.M.; Copp, A.J.. "Epithelial fusion during neural tube morphogenesis". Birth Defects Research Part A - Clinical and Molecular Teratology 94 10 (2012): 817-823. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867664875&partnerID=MN8TOARS.
    10.1002/bdra.23072
  11. Rolo, A.; Skoglund, P.; Keller, R.. "Morphogenetic movements driving neural tube closure in Xenopus require myosin IIB". Developmental Biology 327 2 (2009): 327-338. http://www.scopus.com/inward/record.url?eid=2-s2.0-60549087346&partnerID=MN8TOARS.
    10.1016/j.ydbio.2008.12.009
  12. de Almeida, I.; Rolo, A.; Batut, J.; Hill, C.; Stern, C.D.; Linker, C.. "Unexpected activities of Smad7 in Xenopus mesodermal and neural induction". Mechanisms of Development 125 5-6 (2008): 421-431. http://www.scopus.com/inward/record.url?eid=2-s2.0-41949084151&partnerID=MN8TOARS.
    10.1016/j.mod.2008.02.002
  13. Skoglund, P.; Rolo, A.; Chen, X.; Gumbiner, B.M.; Keller, R.. "Convergence and extension at gastrulation require a myosin IIB-dependent cortical actin network". Development 135 14 (2008): 2435-2445. http://www.scopus.com/inward/record.url?eid=2-s2.0-50249120626&partnerID=MN8TOARS.
    10.1242/dev.014704
Distinctions

Other distinction

2016 Research Excellence Award
University College London Great Ormond Street Institute of Child Health Library, United Kingdom
2006 James Dent Award for Doctoral Students
University of Virginia, United States
2001 PhD Studentship SFRH/BD/4851/2001
Fundação para a Ciência e a Tecnologia, Portugal