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Identification

Personal identification

Full name
Maria Inês Nunes dos Santos
Date of birth
1995/05/10
Gender
Female

Citation names

  • Santos, M. I.

Author identifiers

Ciência ID
7315-ADC4-1D78

Email addresses

  • misantos@cnc.uc.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2022/02 - 2022/02
Concluded
Course "Statistics with SPSS" (Outros)
Faculty of Medicine - University of Coimbra, Portugal
Approved
2021/01 - 2021/06
Concluded
Course "Research Methodologies in Life Sciences, Nature Sciences and Engineering" (Outros)
University of Coimbra, Portugal
16
2018/10/01 - 2020/12/16
Concluded
Pharmaceutical Biotechnology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"MicroRNA profiling in Human Cell-based Models of Machado-Joseph Disease" (THESIS/DISSERTATION)
18/20
2020/08 - 2020/10
Concluded
Summer course "Scientific Research Methodologies: stem cell therapies" (Outros)
Institute of Interdisciplinary Research, University of Coimbra, Portugal
Approved
2019/10 - 2019/10
Concluded
Elsevier workshop "How to Get Published" (Outros)
University of Coimbra, Portugal
2019/09 - 2019/09
Concluded
Workshop in "Hazardous Hospital Waste Management" by AMBIWASTE (Outros)
Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
2019/09 - 2019/09
Concluded
Workshop in "Laboratory Safety" and "BSL 2" (Outros)
Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
2013/09 - 2018/01
Concluded
Biology (branch of Molecular and Genetics) (Licenciatura)
Major in Molecular Biology and Genetics
Universidade de Lisboa Faculdade de Ciências, Portugal
13/20
2015/10 - 2015/10
Concluded
Intensive Course in Criminology (Outros)
Major in Criminal and Forensic Sciences
Instituto CRIAP, Portugal
20/20
Affiliation

Science

Category
Host institution
Employer
2022/02/16 - Current Researcher (Research) Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
2021/04/05 - 2021/10/05 Researcher (Research) Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
2019/04 - 2021/03/31 Research Trainee (Research) Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
Center for Neuroscience and Cell Biology - University of Coimbra, Portugal
2017/02 - 2018/07 Research Trainee (Research) LETAL - Centre for Nuclear Sciences and Technologies (C2TN-IST) , Portugal
Centre for Nuclear Sciences and Technologies (C2TN), Portugal
Outputs

Publications

Conference poster
  1. Santos, D.; Santos, M. I.; Baganha, R.; Nobre, R. ; Figiel, M.; Pereira de Almeida, L.; Duarte, S.. "MicroRNAs as cornerstones in Machado-Joseph disease pathogenesis: development of a microRNA-based gene therapy". Paper presented in European Society of Gene & Cell Therapy - ESGCT 29th Congress, 2022.
  2. Santos, D.; Santos, M. I.; Baganha, R.; Nobre, R. ; Figiel, M.; Pereira de Almeida, L.; Duarte, S.P.. "Investigating microRNA dysregulation towards the development of a microRNA-based therapy for Spinocerebellar ataxia type-3|Machado-Joseph disease (SCA3|MJD)". Paper presented in SPDMOV 2022, 2022.
  3. Santos, M. I.; Oliveira, A. D. (111E-3966-36A9); Pinto, M. M.; Santana, M. M. (3E17-9ED3-1C8D); Santos, D.; Álvaro, A. R.; Pereira de Almeida, L.; Duarte, S.P.. "MiRNA Dysregulation In Machado Joseph Disease What Can We Learn From Human Induced Pluripotent Stem Cell based Models?". Paper presented in XVII Congress of the Portuguese Society of Neuroscience, 2021.
  4. Santos, D.; Santos, M. I.; Baganha, R.; Nobre, R. ; Pereira de Almeida, L; Duarte, S.P.. Corresponding author: Santos, D.. "Restoration Of Dysregulated MiRNA Levels In A Transgenic Mouse Model Of Machado Joseph Disease As A Novel Therapeutic Approach". Paper presented in XVII Congress of the Portuguese Society of Neuroscience, 2021.
Newspaper article
  1. Vinhas, A. C.; Ferreira A. C. (9D16-BDFB-BD29); Henriques, C.; Silva, C.; Miranda, C; Henriques, D.; Oliveira, A. D. (111E-3966-36A9); et al. "Uma viagem rara", Público, 2020, https://www.publico.pt/2020/02/28/ciencia/fotogaleria/viagem-rara-400481.
Thesis / Dissertation
  1. "MicroRNA profiling in human cell-based models of Machado-Joseph disease". Master, Faculty of Pharmacy - University of Coimbra, 2020.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/10/28 MicroRNAs at the cornerstone of Machado-Joseph Disease pathogenesis: Leveraging disease-associated miRNA dysregulation to develop microRNA-based therapeutics 4th meeting of the CIBB thematic area 'Innovative Therapies'
CIBB - Centre for Innovative Biomedicine and Biotechnology (Coimbra, Portugal)
2022/02/09 Induced Pluripotent Stem cells derived from Machado Joseph Disease patients as a promising model to investigate microRNA dysregulation 52nd Meeting of the Portuguese Society of Pharmacology, 40th Meeting of Clinical Pharmacology and 21st Meeting of Toxicology
Portuguese Society of Pharmacology (Porto, Portugal)
2022/02/09 Reverting dysregulation of microRNA levels as a promising therapeutic strategy for Machado-Joseph Disease 52nd Meeting of the Portuguese Society of Pharmacology, 40th Meeting of Clinical Pharmacology and 21st Meeting of Toxicology
Portuguese Society of Pharmacology (Porto, Portugal)
2021/02/19 Phenotypic Characterization Of Neuronal Cultures Derived From Machado-Joseph Disease Induced Pluripotent Stem Cells 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of Toxicology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021/02/18 Identification Of Dysregulated miRNAS In Human Induced Pluripotent Stem Cell-based Models Of Machado-Joseph Disease: One Step Closer To A Therapeutic Approach? 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of Toxicology
Portuguese Society of Pharmacology (Lisboa, Portugal)

Scientific expedition

Activity description Institution / Organization
2022/03/17 - 2022/03/17 Lecture within the framework of the Brain Awareness Week 2022 - "Neurosciences go to schools". Class of 3rd and 4th graders. Centro Escolar Norton de Matos, Coimbra, Portugal