Carolina Isadora Ferreira Salgado Vilaça Barroso (7212-1076-5BED)

Curriculum Vitae

Carolina Isadora Ferreira Salgado Vilaça Barroso

Carolina Barroso obtained a Bachelor's degree in Aquatic Sciences (ICBAS-UP, 2012), a Master's degree in Biological Aquatic Resources (FCUP-UP, 2014), and a Ph.D. in Molecular and Cell Biology (ICBAS/FCUP-UP, 2022). Her scientific career began at the Fish Nutrition and Immunobiology Group (CIIMAR) as an undergraduate student (2011-2012), where she conducted research on the effects of a multispecies probiotic on Senegalese sole growth and immune responses. For her Master's thesis (2013-2014), she investigated the partial replacement of fish meal with carob seed germ meal in diets for meagre, analyzing growth, hematological, and immune parameters (PP-IJUP2012-SOJA DE PORTUGAL-20). In 2016, she joined the Iron and Innate Immunity Group (i3S/IBMC) as a research fellow, to study antimicrobial peptides (AMPs) in European sea bass (NORTE-01-0145-FEDER-000012). In 2017, she was awarded a Ph.D. scholarship through a competitive call from FCT (SFRH/BD/114899/2016), to further pursue her studies focused on the roles and applications of sea bass-derived AMPs in models of infection and iron modulation. Her doctoral research culminated in five publications, including three as first and corresponding author (Int. J. Mol. Sci. 2020; Pharmaceuticals 2021; Front. Immunol. 2021). From September to December 2022, she worked as a research intern at REQUIMTE LAQV, ICBAS, on the project Bugs@Pets (POCI-01-0247-FEDER-047042). In January 2023, she became a junior researcher under the NovInDog project (POCI-01-0247-FEDER-047003) and contributed to HealthyPetFood (POCI-01-0247-FEDER-047073), resulting in a co-authored publication (Front. Vet. Sci. 2024). During this period, she also authored a literature review on the benefits of dietary vitamins, minerals, and phytonutrients on canine immune responses (Vet. Sci. 2024). Currently, she holds a postdoctoral fellowship at the same institute (REQUIMTE 2024-03; UIDB/50006/2020), advancing her expertise in the development of functional and sustainable formulations for pet food. Throughout her career, Carolina Barroso has published 11 articles and participated in several national and international conferences. She also co-supervised two undergraduate students (Aquatic Sciences, ICBAS) and has been invited to review for Fish & Shellfish Immunology and Veterinary Medicine and Science. She has acquired expertise in various animal models (fish, mice and dogs) and techniques, including nucleic acid extraction, cloning, bioinformatics, real-time PCR, cell culture, flow cytometry, and ELISA.

Read full resume ↓

Identification

Personal identification

Full name: Carolina Isadora Ferreira Salgado Vilaça Barroso

Citation names

Barroso, Carolina
Barroso, C.

Author identifiers

Ciência ID: 7212-1076-5BED
ORCID iD: 0000-0002-3972-9857
Researcher Id: HHM-5309-2022
Scopus Author Id: 57225799813

Email addresses

cibarroso@icbas.up.pt (Professional)

Telephones

Telephone

220 428 00 (Professional)

Addresses

Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Porto, Portugal (Professional)

Knowledge fields

Natural sciences - Biological Sciences - Marine Biology
Agrarian Sciences - Animal and Dairy Science - Pets
Natural sciences - Biological Sciences - Molecular Biology
Medical and Health Sciences - Basic Medicine - Immunology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Upper intermediate (B2)	Upper intermediate (B2)	Advanced (C1)	Advanced (C1)	Upper intermediate (B2)

Education

	Degree	Classification
2017 - 2022/07/12 Concluded	Molecular and Cell Biology (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Novel antimicrobial peptides from sea bass (Dicentrarchus labrax) and their potential applications for the improvement of aquaculture production" (THESIS/DISSERTATION)	Approved
2017 - 2017 Concluded	FELASA Introductory course in Laboratory Animal Science Category B (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2012 - 2014 Concluded	Biological Aquatic Resources (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal "Effects of partial replacement of fish meal by carob seed germ meal on growth performance and immune parameters of meagre (Argyrosomus regius, Asso, 1801)." (THESIS/DISSERTATION)	17/20
2009 - 2012 Concluded	Aquatic Sciences (Licenciatura) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Estudo de crescimento no linguado (Solea senegalensis) e infeção por Photobacterium damselae spp piscicida." (THESIS/DISSERTATION)	15/20

Affiliation

Science

	Category Host institution	Employer
2023/01/01 - 2024/02/29	Contracted Researcher (Research)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	REQUIMTE LAQV Porto, Portugal
2022/09/01 - 2022/12/31	Research Trainee (Research)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	REQUIMTE LAQV Porto, Portugal

Others

	Category Host institution	Employer
2024/03/01 - Current	Postdoctoral Fellow supported by REQUIMTE 2024-03; UIDB/50006/2020	REQUIMTE LAQV Porto, Portugal
	REQUIMTE LAQV Porto, Portugal
2021/11 - 2022/04	Research Fellow supported by NORTE-01-0145-FEDER-000040	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/05 - 2021/10	PhD Student supported by SFRH/BD/114899/2016; COVID/BD/151662/2021	Fundação para a Ciência e a Tecnologia, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/11 - 2017/04	Research Fellow supported by NORTE-01-0145-FEDER-000012	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/02 - 2016/04	Research Technician	Sparos Lda, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/03 - 2015/08	Research Technician	Sparos Lda, Portugal
	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/09 - 2014/11	Master Student	Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

2011/09 - 2012/07	Trainee	Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Projects

Grant

	Designation	Funders
2021/11 - 2022/04	ATLANTIDA - Platform for the monitoring of the North Atlantic Ocean and tools for the sustainable exploitation of the marine resources NORTE-01-0145-FEDER-000040 Research Fellow Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	European Regional Development Fund Concluded
2017/05 - 2021/10	Novel antimicrobial peptides from sea bass (Dicentrarchus labrax) and their potential applications for the improvement of aquaculture production SFRH/BD/114899/2016 COVID/BD/151662/2021 PhD Student Fellow Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/11 - 2017/04	Structured Programme on Bioengineering Therapies for Infectious Diseases and Tissue Regeneration NORTE-01-0145-FEDER-000012 Research Fellow Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	European Regional Development Fund Concluded

Contract

	Designation	Funders
2023/01/01 - 2023/06/30	NovInDog - New functional protein ingredients for the feeding of dogs: a sustainable approach POCI-01-0247-FEDER-047003 Researcher Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	COMPETE/PORTUGAL2020 Concluded
2022/09/01 - 2023/06/30	BUGS@PETS - Development of new insect ingredients for incorporation into complete compound foods for pets POCI-01-0247-FEDER-047042 Researcher Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	COMPETE/PORTUGAL2020 Concluded

Other

	Designation	Funders
2013/09 - 2014/11	IJUP 2012 - Carob seed germ meal as a partial fish meal substitute in diets for meagre (Argyrosomus regius): growth, digestibility and health status PP-IJUP2012-SOJA DE PORTUGAL- 20 Master Student	Soja de Portugal Concluded

Outputs

Publications

Conference poster	Carolina Barroso; Ana R. J. Cabrita; António J. M. Fonseca. "Minerals, vitamins, and phytonutrients as modulators of canine immune function". Paper presented in XIII Jornadas e II Fórum de Alimentação Animal, 2024. Joana Guilherme-Fernandes; Barroso, Carolina; Tiago Aires; António J.M. Fonseca; Sofia A.C. Lima; Margarida R.G. Maia; Ana R.J. Cabrita. "Evaluation of alternative marine sources as protein ingredients in pet food". Paper presented in 48th World Small Animal Veterinary Association Congress, 2023. Barroso, Carolina; Carvalho, Pedro; Gonçalves, José F.M.; Rodrigues, Pedro N.S.; Neves, João V.. Corresponding author: Barroso, Carolina. "Identification and characterization of two beta-defensins in the European sea bass Dicentrarchus labrax". Paper presented in Aquaculture Europe – Oceans of Opportunity, European Aquaculture Society, 2021. Barroso, Carolina; Pedro Carvalho; Carla Carvalho; Nuno Santarém; José F. M. Gonçalves; Pedro N. S. Rodrigues; João V. Neves. "Piscidins in the European sea bass Dicentrarchus labrax: different antimicrobial activities for different peptides". Paper presented in Aquaculture Europe 2020, European Aquaculture Society, 2021. Barroso, Carolina; Neves, João V.; Rodrigues, Pedro N.S.. "Insights into the functions of piscidins in the European sea bass (Dicentrarchus labrax)". Paper presented in 3rd International Conference on Fish & Shellfish Immunology, 2019. Carolina Barroso; João V. Neves; Pedro N. S. Rodrigues. "Unravelling the functions of piscidins, the fish specific antimicrobial peptides.". Paper presented in 7th i3S Annual Meeting, 2018. Carolina Barroso; João V. Neves; Pedro N. S. Rodrigues. "Unravelling the functions of piscidins, the fish specific antimicrobial peptides.". Paper presented in 3rd MCBiology Symposium: The Secret Life of the Cell, 2018. Guardiola, Francisco A.; Barroso, Carolina; Enes, Paula; Couto, Ana; Díaz-Rosales, Patricia; Afonso, António; Kanashiro, Erika; et al. "Mucosal immune responses in meagre (Argyrosomus regius) juveniles fed diets with varying inclusion levels of carob seed germ meal.". Paper presented in 31st Congress of the New European Society for Comparative Physiology and Biochemistry (ESCPB), 2018. Carolina Barroso; João V. Neves; Pedro N. S. Rodrigues. "Putative new functions for piscidins, an antimicrobial peptide from sea bass.". Paper presented in XLIV SPI Annual Meeting - Sociedade Portuguesa de Imunologia, 2018. Carolina Barroso; João V. Neves; Pedro N. S. Rodrigues. "Putative new functions for piscidins, an antimicrobial peptide from sea bass.". Paper presented in 1st PhDay at i3S - From bench to stage, from desk to forum, 2018. Carolina Barroso; Ana Couto; Paula Enes; Patrícia Díaz-Rosales; António Afonso; Elisabete Matos; Helena Peres; Aires Oliva-Teles; Benjamín Costas. "Blood cells and gut immune parameters of meagre (Argyrosomus regius) are unaffected by high dietary carob seed germ meal.". Paper presented in IV Encontro Nacional de Pós-graduação em Ciências Biológicas, 2015. Carolina Barroso; Paula Enes; Patrícia Díaz-Rosales; Helena Peres; Elisabete Matos; António Afonso; Aires Oliva-Teles; Benjamín Costas. "Partial fish meal replacement by carob seed germ meal influences meagre Argyrosomus regius immune parameters.". Paper presented in AQUACULTURE EUROPE 14 - "Adding Value" Organized by “European Aquaculture Society”, 2014.
Journal article	Barroso, Carolina; Fonseca, António J. M.; Cabrita, Ana R. J.. "Vitamins, Minerals and Phytonutrients as Modulators of Canine Immune Function: A Literature Review". Veterinary Sciences 11 12 (2024): 655. https://doi.org/10.3390/vetsci11120655. Published • 10.3390/vetsci11120655 Cabrita, Ana R. J.; Barroso, Carolina; Fontes-Sousa, Ana Patrícia; Correia, Alexandra; Teixeira, Luzia; Maia, Margarida R. G.; Vilanova, Manuel; et al. "Assessing functional properties of diet protein hydrolysate and oil from fish waste on canine immune parameters, cardiac biomarkers, and fecal microbiota". Frontiers in Veterinary Science 11 (2024): 1449141. http://dx.doi.org/10.3389/fvets.2024.1449141. Open access • Published • 10.3389/fvets.2024.1449141 Neves, João V.; Barroso, Carolina; Carvalho, Pedro; Nunes, Magda; Gonçalves, José F. M.; Rodrigues, Pedro N. S.. "Characterization of Erythroferrone in a Teleost Fish (Dicentrarchus labrax) With Two Functional Hepcidin Types: More Than an Erythroid Regulator". Frontiers in Immunology 13 867630 (2022): http://dx.doi.org/10.3389/fimmu.2022.867630. Published • 10.3389/fimmu.2022.867630 Barroso, Carolina; Carvalho, Pedro; Nunes, Magda; Gonçalves, José F. M.; Rodrigues, Pedro N. S.; Neves, João V.. Corresponding author: Barroso, Carolina. "The Era of Antimicrobial Peptides: Use of Hepcidins to Prevent or Treat Bacterial Infections and Iron Disorders". Frontiers in Immunology 12 754437 (2021): http://dx.doi.org/10.3389/fimmu.2021.754437. Published • 10.3389/fimmu.2021.754437 Barroso, Carolina; Carvalho, Pedro; Gonçalves, José F. M.; Rodrigues, Pedro N. S.; Neves, João V.. Corresponding author: Barroso, Carolina. "Antimicrobial Peptides: Identification of Two Beta-Defensins in a Teleost Fish, the European Sea Bass (Dicentrarchus labrax)". Pharmaceuticals 14 6 (2021): 566. http://dx.doi.org/10.3390/ph14060566. Published • 10.3390/ph14060566 João V. Neves; Ana C. Gomes; David M. Costa; Carolina Barroso; Sophie Vaulont; Anabela Cordeiro da Silva; Joana Tavares; Pedro N.S. Rodrigues. "A role for hepcidin in the anemia caused by Trypanosoma brucei infection". Haematologica 106 3 (2021): 806-818. http://dx.doi.org/10.3324/haematol.2019.227728. Published • 10.3324/haematol.2019.227728 Barroso, Carolina; Carvalho, Pedro; Carvalho, Carla; Santarém, Nuno; Gonçalves, José F. M.; Rodrigues, Pedro N. S.; Neves, João V.. Corresponding author: Barroso, Carolina. "The Diverse Piscidin Repertoire of the European Sea Bass (Dicentrarchus labrax): Molecular Characterization and Antimicrobial Activities". International Journal of Molecular Sciences 21 13 (2020): 4613. http://dx.doi.org/10.3390/ijms21134613. Published • 10.3390/ijms21134613 Barroso, C.; Neves, J.V.; Rodrigues, P.N.. "Insights into the functions of piscidins in the European sea bass (Dicentrarchus labrax)". Fish & Shellfish Immunology 91 (2019): 396. http://dx.doi.org/10.1016/j.fsi.2019.04.089. Published • 10.1016/j.fsi.2019.04.089 Guardiola, Francisco Antonio; Barroso, Carolina; Enes, Paula; Couto, Ana; Díaz-Rosales, Patricia; Afonso, António; Kanashiro, Erika; et al. "Humoral and mucosal immune responses in meagre (Argyrosomus regius) juveniles fed diets with varying inclusion levels of carob seed germ meal (These authors contributed equally to this work)". Fish & Shellfish Immunology 79 (2018): 209-217. http://dx.doi.org/10.1016/j.fsi.2018.05.027. Published • 10.1016/j.fsi.2018.05.027 Barroso, Carolina; Ozório, Rodrigo O A; Afonso, António; Moraes, Julieta R E; Costas, Benjamín. "Immune responses and gut morphology in Senegalese sole (Solea senegalensis) fed dietary probiotic supplementation and following exposure toPhotobacterium damselaesubsp.piscicida". Aquaculture Research 47 3 (2016): 951-960. http://dx.doi.org/10.1111/are.12553. Published • 10.1111/are.12553 Couto, A.; Barroso, C.; Guerreiro, I.; Pousão-Ferreira, P.; Matos, E.; Peres, H.; Oliva-Teles, A.; Enes, P.. "Carob seed germ meal in diets for meagre (Argyrosomus regius) juveniles: Growth, digestive enzymes, intermediary metabolism, liver and gut histology". Aquaculture 451 (2016): 396-404. http://dx.doi.org/10.1016/j.aquaculture.2015.10.007. Published • 10.1016/j.aquaculture.2015.10.007
Thesis / Dissertation	"Novel antimicrobial peptides from sea bass (Dicentrarchus labrax) and their potential applications for the improvement of aquaculture production". PhD, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2022. Barroso, Carolina. "Effects of partial replacement of fish meal by carob seed germ meal on growth performance and immune parameters of meagre (Argyrosomus regius, Asso, 1801)". Master, Universidade do Porto Faculdade de Ciências, 2014. Barroso, Carolina. "Estudo de crescimento no linguado (Solea senegalensis) e infeção por Photobacterium damselae spp piscicida". Degree, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2012.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/09/19	Unveiling the effects of shrimp hydrolysate as a dietary supplement in healthy adult Beagle dogs	XIII Jornadas e II Fórum de Alimentação Animal (Santarém, Portugal)
2024/09/19	Insect hydrolysates for dogs: impact on nutritional and health parameters	XIII Jornadas e II Fórum de Alimentação Animal (Santarém, Portugal)
2024/09/13	Influence of dietary inclusion of black soldier fly hydrolysates on palatability, digestibility and cardiac biomarkers of adult Beagle dogs	ESVCN 2024 European Society of Veterinary & Comparative Nutrition (Belfast, Ireland)
2024/06/13	Impact of feeding a new sustainable insect hydrolysate to adult Beagle dogs on diet digestibility and cardiac health	One Health PhD Forum Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2023/10/13	Impact of insect hydrolysates supplementation on diet palatability, digestibility and faecal characteristics of adult dogs	Workshop of the Animal Science Doctoral Programme 2023 Animal Science Doctoral Programme (Vila do Conde, Portugal)
2021/11	The potential of sea bass Dicentrarchus labrax derived hepcidins in the treatment of iron disorders and bacterial infections	Aquaculture Europe - Oceans of Opportunity, Organized by European Aquaculture Society (Funchal, Madeira)
2021/01	The multiple functions of piscidins in the European sea bass (Dicentrarchus labrax)	5th Molecular and Cell Biology Symposium: "Science Must Go On" Molecular and Cell Biology PhD Program 7th Edition, Instituto de Investigação e Inovação em Saúde (Porto, Portugal)
2019/10	The multiple functions of piscidins in the European sea bass (Dicentrarchus labrax).	Aquaculture Europe - Our Future Growing From Water, Organized by European Aquaculture Society (Berlim, Germany)
2018/12	Unravelling the functions of piscidins, the fish specific antimicrobial peptides	TiBE2018, Trends in Biodiversity and Evolution – HOST-PARASITE INTERACTIONS (Vairão - Vila do Conde, Portugal)
2017/11	Beyond antimicrobial activity: novel functions for piscidins in European sea bass (Dicentrarchus labrax)	6th i3S Annual Meeting (Póvoa do Varzim, Portugal)
2014/02	Carob seed germ meal as a partial fish meal substitute in diets for meagre (Argyrosomus regius): growth and health status	7º Encontro Investigação Jovem da Universidade do Porto (Porto, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2021 - 2022	Antimicrobial Peptides: a promising future for aquaculture Co-supervisor	Aquatic Sciences (Degree) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2019	Antimicrobial peptides: the roles of ß-defensins in a teleost fish, the European sea bass (Dicentrarchus labrax) Co-supervisor	Aquatic Sciences (Degree) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2018/11/22 - 2018/11/22	3rd Symposium MCbiology PhD Program: "The Secret Life of the Cell" (2018/11/22 - 2018/11/22) Symposium (Member of the Organising Committee)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2011/02/25 - 2011/02/27	I Jornadas da Ciência e Tecnologia Aquáticas - AEICBAS, Associação de Estudantes do Instituto de Ciências Biomédicas Abel Salazar (2011/02/25 - 2011/02/27)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2025/01 - Current	Veterinary Medicine and Science (2053-1095)	Wiley
2020/12 - 2021/12	Fish and Shellfish Immunology (1050-4648)	Elsevier

Association member

	Society Organization name	Role
2018/06 - Current	Sociedade Portuguesa de Imunologia	Member
2010/09 - 2011/07	AEICBAS - Associação de Estudantes do Instituto de Ciências Biomédicas Abel Salazar	External Collaborator

Distinctions

Other distinction

2017	PhD Scholarship (SFRH/BD/114899/2016) Fundação para a Ciência e a Tecnologia, Portugal