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Augusto Pedro (AQP) holds an MSc in Biochemistry (UBI, 2009) and a PhD in Biochemistry (UBI, 2016). His research focuses on stabilizing, producing, and purifying protein- and nucleic acid–based biopharmaceuticals. Early work included PEGylated protein purification and bacterial expression of a Parkinson’s-related enzyme. As a postdoc at CICECO, he joined the ERC project IgYPurTech and developed ionic liquid–based strategies for biopharmaceutical stabilization, including mRNA. He was a visiting researcher at CBM, University of Orléans (2019), and became a Junior Researcher at the University of Aveiro (2021) under the competitive FCT/CEEC award. AQP has secured ~€610k in competitive funding as PI/co-PI, co-invented three patents, and published 34 peer-reviewed articles. He supervises several PhD students, contributes to technology transfer and innovation programs, and co-founded the UAVR-RNA Club. In 2023, he received the CICECO Young Investigator Award.
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Identification

Personal identification

Full name
Augusto Quaresma Henriques Pedro

Citation names

  • Augusto Pedro
  • Augusto Q. Pedro
  • A. Q. Pedro

Author identifiers

Ciência ID
7111-B2BE-336D
ORCID iD
0000-0001-8194-6022
Google Scholar ID
https://scholar.google.com/citations?user=oer44UoAAAAJ&hl=pt-PT&oi=ao
Scopus Author Id
54080426100

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology
  • Engineering and Technology - Industrial Biotechnology - Industrial Biotechnology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Engineering and Technology - Industrial Biotechnology - Fermentation
  • Exact Sciences - Chemical Sciences - Analytical Chemistry
  • Engineering and Technology - Industrial Biotechnology - Industrial Biotechnology
  • Engineering and Technology - Industrial Biotechnology - Industrial Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2) Upper intermediate (B2)
Spanish; Castilian Elementary (A2) Upper intermediate (B2) Beginner (A1) Intermediate (B1) Elementary (A2)
Portuguese (Mother tongue)
Education
Degree Classification
2016
Concluded
 Biochemistry (Doutoramento)
Universidade da Beira Interior Faculdade de Ciências, Portugal
"Biosynthesis, isolation and kinetic characterization of recombinant human catechol-O-methyltransferase from Pichia pastoris strains " (THESIS/DISSERTATION)
 Excellent
2011
Concluded
 Biochemistry (Mestrado)
Major in Industrial Biotechnology
Universidade da Beira Interior Faculdade de Ciências, Portugal
"Biosynthesis, solubilization and purification of human membrane bound Catechol-O-Methyltransferase in Brevibacillus choshinensis cells " (THESIS/DISSERTATION)
 18
2009
Concluded
 Biochemistry (Licenciatura)
Universidade da Beira Interior Faculdade de Ciências, Portugal
""Tryptase use as a diagnostic marker in patients with monoclonal gammophaties."" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2019/05 - Current Contracted Researcher (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2019/06/22 - 2019/07/05 Visiting Researcher (Research) Centre de Biophysique Moléculaire, France
Centre de Biophysique Moléculaire, France
(...)
2019/02 - 2019/05 Postdoc (Research) Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro CICECO, Portugal
2016/09 - 2019/02 Postdoc (Research) Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro CICECO, Portugal
2012/01/01 - 2016/02/29 Researcher (Research) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2010/09 - 2011/06 Researcher (Research) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2010/07/01 - 2010/08/31 Visiting Researcher (Research) Politechnika Lodzka Instytut Chemii Ogólnej i Ekologicznej, Poland
Politechnika Lodzka Instytut Chemii Ogólnej i Ekologicznej, Poland

Teaching in Higher Education

Category
Host institution 		Employer
2021/02 - Current Invited Assistant (University Teacher) Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Química, Portugal
2012/09/01 - 2016/02/01 Invited Assistant (University Teacher) Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal

Others

Category
Host institution 		Employer
2022/01/17 - 2024/01/16 mVACCIL - Improving the manufacturing of mRNA vaccines applying ionic liquids and integrated production-clarification processes - EXPL/BII-BTI/0731/2021. FCT. Principal Investigator Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro CICECO, Portugal
2018/07/01 - 2022/06/30 IL2BioPro - Towards the improvement of recombinant proteins bioprocessing using ionic liquids. FCT, Portuguese Foundation for Science and Technology, POCI-01-0145-FEDER-030840. Principal Investigator Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro CICECO, Portugal
2014 - 2016 Responsible of the Centrifuge Laboratory Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2009/01/01 - 2009/12/13 Participation as a volunteer in a scientific project about the separation and purification of pegylated proteins, under the supervision of Professor Ana Cristina Dias-Cabral. Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Projects

Grant

Designation Funders
2022/01 - 2023/07 Melhorias na obtenção de vacinas de ARN mensageiro utilizando líquidos iónicos e processos integrados de produção-clarificação
Provided by PTCRIS: EXPL/BII-BTI/0731/2021
 Fundação para a Ciência e a Tecnologia
2018/07 - 2022/06 Melhorias no bioprocessamento de proteínas recombinantes utilizando líquidos iónicos
Provided by PTCRIS: PTDC/BII-BBF/30840/2017
 Fundação para a Ciência e a Tecnologia
2019/02 - 2019/05 Sustainable purification platforms for RNA
FCT IF/01634/2015
Post-doc Fellow
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/09 - 2019/01 IgY Technology: A Purification Platform using Ionic-Liquid-Based Aqueous Biphasic Systems (IgYPurTech)
2013-StG-337753
Post-doc Fellow
Universidade de Aveiro CICECO, Portugal
 European Research Council
Concluded
2012/01/01 - 2016/12/31 Biosynthesis, isolation and kinetic characterization of recombinant human catechol-O-methyltransferase isolated from Pichia pastoris
SFRH/BD/81222/2011
SFRH/BD/81222/2011
PhD Student Fellow
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluded
2012/01 - 2015/12 BIOINTERACTION OF PARKINSON´S INHIBITORS AND HUMAN MEMBRANE-BOUND CATECHOL-O-METHYLTRANSFERASE ISOLATED FROM PICHIA PASTORIS
Provided by PTCRIS: SFRH/BD/81222/2011
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2021 - Current Cost-effective and sustainable purification platforms for protein-based biopharmaceuticals - 2020.02599.CEECIND
2020.02599.CEECIND
Researcher
Universidade de Aveiro, Portugal

Universidade de Aveiro Departamento de Química, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Suportes modificados com Liquidos Iónicos para a Purificação de pré-miRNAs envolvidos na doença de Alzheimer
PTDC/BII-BBF/29496/2017
Provided by PTCRIS: PTDC/BII-BBF/29496/2017
Universidade de Aveiro, Portugal

Universidade da Beira Interior, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Ongoing
2019/05 - 2021 IL2BioPro: Towards the improvement of recombinant proteins bioprocessing using ionic liquids
PTDC/BII-BBF/030840/2017
Researcher
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 CICECO-Instituto de Materiais de Aveiro
UID/CTM/50011/2019
LA/P/0006/2020
10.54499/LA/P/0006/2020
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2025/09/01 - Current Customized ionic liquid patches for efficient and non-invasive transdermal delivery of messenger RNA vaccines (Refª FCT: 16593))
COMPETE2030-FEDER-00777000 (Refª FCT: 16593)
Principal investigator
Ongoing
2025/06/01 - Current Integrated extraction-preservation of bioproduced messenger RNA using biobased ionic liquids
2024.07305.CBM
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01 - 2025/12 PRR - Recovery and Resilience Plan Agenda for Business Innovation InsectERA
C644917393-00000032
Researcher
Universidade de Aveiro CICECO, Portugal
Ongoing
2022/03 - 2025/09/30 Yscript: Yeast cell factory for mRNA bioproduction
101047214
Researcher
Universidade de Aveiro CICECO, Portugal
 European Innovation Council
Concluded
2023/01/01 - 2024/06/30 PureDNA: Development of cost-effective platforms based on ionic liquids for the purification of p53-minicircle DNA biopharmaceuticals with application in oncology
2022.03394.PTDC
Co-Principal Investigator (Co-PI)
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/17 - 2024/01/16 mVACCIL - Improving the manufacturing of mRNA vaccines applying ionic liquids and integrated production-clarification processes (EXPL/BII-BTI/0731/2021, FCT)
EXPL/BII-BTI/0731/2021
Principal investigator
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Unidade de Investigação em Governança Competitividade e Políticas Públicas, Portugal

Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07 - 2022/06/30 IL2BioPro: Towards the improvement of recombinant proteins bioprocessing using ionic liquids
PTDC/BII-BBF/030840/2017
Principal investigator
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2022 PUREmirSils: Ionic liquid-based supports for pre-miRNAs purification targeting Alzheimers disease
POCI-01-0145-FEDER-029496
Researcher
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2019/12 Pre-miRNAs for Alzheimers disease therapy: biosynthesis, purification and delivery
Acordo bilateral FCT-PHC (Programa Pessoa)
Researcher
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012 - 2014 Biosynthesis, purification and biointeraction of human soluble catechol-O-methyltransferase with Parkinson´s inhibitors
Provided by PTCRIS: 128284
128284
EXPL/BBB478/BQB/0960/2012
Researcher
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
Outputs

Publications

Book chapter
  1. Augusto Pedro. "Ionogels for Biomedical Applications". 391-425. Springer Singapore, 2022.
    10.1007/978-981-16-7483-9_18
  2. Inês S. Cardoso; Augusto Q. Pedro (7111-B2BE-336D); Armando J. D. Silvestre; Mara G. Freire. "Ionic Liquids and Deep Eutectic Solvents in the Field of Environmental Monitoring". In Green Chemistry and Sustainable Technology, edited by Justyna Plotka-Wasylka; Jacek Namiesnik, 203-240. Singapore: Springer Singapore, 2019.
    Published • 10.1007/978-981-13-9105-7_8
  3. Augusto Q. Pedro (7111-B2BE-336D); João A. P. Coutinho; Mara G. Freire. "Immobilization of Ionic Liquids, Types of Materials, and Applications". In Encyclopedia of Ionic Liquids, edited by Suojiang Zhang, 1-12. Singapore: Springer Singapore, 2019.
    Published • 10.1007/978-981-10-6739-6_86-1
Conference abstract
  1. Luís António Paulino Passarinha; Filipa Correia; Augusto Q. Pedro; Diana Oliveira; João António de Sampaio Rodrigues Queiroz. "Biosynthesis, purification and biointeraction of human SCOMT with Parkinson's disease inhibitors". Paper presented in 16th European Congress on Biotechnology, New Biotechnology, Edinburgh, 2014.
    Published • 10.1016/j.nbt.2014.05.942
Conference poster
  1. Ana I. Valente; Valente, João V.; Athenas De Francesco; Augusto Q. Pedro; Tavares, Ana P. M.; Sousa, F; Mara G. Freire. "mcDNA isolation from cell lysates via ionic liquids-based aqueous biphasic systems". Paper presented in 7th IMIL - Iberoamerican Meeting on Ionic Liquids, 2024.
  2. Ana S. C. Marques; João L. P. Fernandes; Augusto Q. Pedro; Cristine Gonçalves; Fani Sousa; Ana P.M.Tavares; Chantal, PICHON; Mara G. Freire. Corresponding author: Ana S. C. Marques. "Integrated process for the recovery and purification of recombinant messenger RNA vaccines resorting to ionic liquids". Paper presented in 12th International mRNA Health Conference, Boston, United States, 2024.
  3. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Tavares, Ana P. M.; Branco, Luis; Coutinho, Joao A. P.; Fani Sousa; Mara G. Freire. "Towards the selective isolation of bacterial RNA resorting to three-phase partitioning systems composed of amino-acid-based ionic liquids". Paper presented in Jornadas CICECO 24, 2024.
  4. Capela, Emanuel V.; Jéssica Bairos; Augusto Q. Pedro; Márcia C. Neves; M. Raquel Aires-Barros; Ana M. Azevedo; João A.P. Coutinho; Ana P.M. Tavares; Mara G. Freire. "Towards the purification of human antibodies using customizable supported ionic liquids as promising alternative matrices". Paper presented in 7th Iberoamerican Meeting on Ionic Liquids (IMIL2024), 2024.
  5. Maria I. Sousa; Andreia Correia; Mara G. Freire; Francisca A. e Silva; Augusto Q. Pedro. "Improving the manufacturing of mRNA vaccines with an integrated production-clarification process". Paper presented in Jornadas CICECO 2024, 2024.
  6. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Tavares, Ana P. M.; Branco, Luis; Coutinho, Joao A. P.; Fani Sousa; Mara G. Freire. "Effective separation of nucleic acids from complex bacterial lysates using three-phase partitioning systems based on biocompatible ionic liquids". Paper presented in ISPPP 2024 - 43rd International Symposium and Exhibit on the Separation, Purification, and Characterization of Biologically Important Molecules, 2024.
  7. Ana S. C. Marques; João L. P. Fernandes; Augusto Q. Pedro; Cristine Gonçalves; Fani Sousa; Ana P.M.Tavares; Ana R. Soares; Chantal, PICHON; Mara G. Freire. Corresponding author: Ana S. C. Marques. "Alternative solvents for the Extraction and Preservation of Nucleic Acid Biopharmaceuticals". Paper presented in 4th International Conference on Natural Products and Human Health, 2024.
  8. Ana I. Valente; João Vasco Valente; Athenas De Francesco; Augusto Q. Pedro; Tavares, Ana P. M.; Sousa, F; Mara G. Freire. "Recovery of mcDNA from cell lysates using ionic-liquid-based aqueous biphasic systems". Paper presented in 6th Meeting in Medicinal Biotechnology, 2024.
  9. Ana S. C. Marques; João L. P. Fernandes; Augusto Q. Pedro; Cristine Gonçalves; Ana P. M. Tavares; Chantal Pichon; Mara G. Freire. Corresponding author: Ana S. C. Marques. "Recovery of recombinant nucleic acid-based biopharmaceuticals using alternative solvents". Paper presented in 6th Meeting of Medicinal Biotechnology, 2024.
  10. Ana S. C. Marques; João L. P. Fernandes; Augusto Q. Pedro; Cristine Gonçalves; Ana P. M. Tavares; Ana Poim; Ana R. Soares; Chantal Pichon; Mara G. Freire. Corresponding author: Ana S. C. Marques. "Integrated extraction-preservation platforms of nucleic acid-based biopharmaceuticals using alternative solvents". Paper presented in VII iBiMED Symposium, 2024.
  11. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Ana P.M.Tavares; Luís C. Branco; Coutinho, Joao A. P.; Fani Sousa; Mara G. Freire. "Improved purification strategies for RNA afforded by the use of biobased ionic liquids as constituents of aqueous biphasic systems". Paper presented in Microbiotec23 - Congress of Microbiology and Biotechnology 2023, 2023.
  12. Maria I. Sousa; Luís C. V. Silva; Mara G. Freire; e Silva, F. A.; Augusto Q. Pedro. "Improving The Manufacturing of mRNA Nanomedicines Using Thermoreversible Aqueous Biphasic Systems and Ionic Liquids". Paper presented in Congress of Microbiology and Biotechnology 2023 (MicroBiotech 2023), 2023.
  13. Ana I. Valente; Castro, Leonor S.; Inês D. Rios; Augusto Pedro; Tavares, Ana P. M.; Sousa, F; Mara G. Freire. "Optimization of the production and purification of non-viral vectors for gene therapy applications". Paper presented in Congress of Microbiology and Biotechnology (Microbiotec'23), 2023.
  14. Ana S. C. Marques; Augusto Q. Pedro; Cristine Gonçalves; Ana P. M. Tavares; Chantal Pichon; Mara G. Freire. "Ionic Liquids: An innovative cell disruption method for the extraction of nucleic acids-based biopharmaceuticals from yeast". Paper presented in MICROBIOTEC 2023 - Congress of Microbiology and Biotechnology, 2023.
  15. Luís C. V. Silva; Maria I. Sousa; Andreia Correia; Mara G. Freire; e Silva, F. A.; Augusto Q. Pedro. "The use of thermoreversible ionic liquid-based aqueous biphasic systems as an integrated production-clarification platform in mRNA vaccines manufacturing". Paper presented in Jornadas CICECO 2023, 2023.
  16. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Ana P.M.Tavares; Luís C. Branco; Coutinho, Joao A. P.; Fani Sousa; Freire, Mara G.. "Integrated purification platforms for RNA resorting to amino-acid-based ionic liquids as constituents of aqueous biphasic systems". Paper presented in Jornadas CICECO 23, 2023.
  17. Ana S. C. Marques; Augusto Q. Pedro; Cristine Gonçalves; Ana P. M. Tavares; Chantal Pichon; Mara G. Freire. Corresponding author: Ana S. C. Marques. "Innovative use of Ionic Liquids for Extracting Nucleic Acid-Based Biopharmaceuticals from Yeast". Paper presented in Jornadas do CICECO 2023, 2023.
  18. João L. Fernandes; Leonor S. Castro; Ana F. Pereira; Ana M. Ferreira; Freire, Mara G.; Pedro J. Carvalho; Augusto Q. Pedro. "Protein recovery from biomass using integrated processes based on ionic liquids". Paper presented in JORNADAS CICECO 2023, 2023.
  19. Ana S. C. Marques; Augusto Q. Pedro; Cristine Gonçalves; Ana P. M. Tavares; Chantal Pichon; Mara G. Freire. Corresponding author: Ana S. C. Marques. "Development of an integrated process for the recovery and purification of recombinant messenger RNA vaccines resorting to bio-based ionic liquids". Paper presented in ChemPor 2023 – International Chemical and Biological Engineering Conference, 2023.
  20. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Ana P.M.Tavares; Luís C. Branco; Coutinho, Joao A. P.; Fani Sousa; Freire, Mara G.. "Integrated purification strategies of RNA from recombinant lysates using biobased ionic liquids". Paper presented in XXVIII Encontro Nacional da SPQ, 2023.
  21. Ana I. Valente; Castro, Leonor S.; I. D. Rios; A. Q. Pedro; Tavares, Ana P. M.; Sousa, F; Mara G. Freire. "Production and purification of non-viral vectors for gene therapy applications". Paper presented in XXVIII Encontro Nacional da SPQ, 2023.
  22. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Tavares, Ana P.M.; Luís C. Branco; Coutinho, Joao A. P.; Fani Sousa; Mara G. Freire. "Extraction and stabilization of RNA using biobased ionic liquids". Paper presented in High Throughput Screening & Process Development – how small can we get?, 2023.
  23. Maria I. Sousa; Mara G. Freire; e Silva, F. A.; Augusto Pedro. "Manufacturing of mRNA nanomedicines using thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in 5º Encontro de Biotecnologia Medicinal, 2022.
  24. Fernandes, João; Castro, Leonor S.; ANA M. FERREIRA; Mara G. Freire; Carvalho, Pedro J.; Augusto Q. Pedro. "Recombinant membrane protein productionusing integrated strategies". Paper presented in Jornadas CICECO 2022, 2022.
  25. Maria I. Sousa; Mara G. Freire; e Silva, F. A.; Augusto Pedro. "Development of integrated strategies for the manufacturing of mRNA resorting to aqueous biphasic systems and ionic liquids". Paper presented in Jornadas CICECO 2022, 2022.
  26. João L. Fernandes; Castro, Leonor S.; Ana M. Ferreira; Mara G. Freire; Pedro J. Carvalho; Augusto Q. Pedro. "Development of integrated processes for the recovery of recombinant membrane proteins". Paper presented in 5º Encontro de Biotecnologia Medicinal - 5EBTM & 2nd Iberian Congress on Medicinal Biotechnology - 2ICMB, 2022.
  27. Magalhães, Flávia F.; Augusto Q. Pedro; Mara G. Freire; Tavares, Ana P. M.. "Recombinant laccase production by Komagataella pastoris and the effect of surfactant". Paper presented in Jornadas CICECO 2022, 2022.
  28. Ana F. Pereira; Augusto Q. Pedro; Leonor S. Castro; Maria J. Quental; Ana P.M.Tavares; Luís C. Branco; Coutinho, Joao A. P.; et al. "Stabilization and purification of RNA using biocompatible ionic liquids". Paper presented in 5EBTM / 2ICMB- 5º Encontro em Biotecnologia Medicinal / 2º Congresso Ibérico em Biotecnologia Medicinal 2022, 2022.
  29. Fernandes, João; Castro, Leonor S.; Carvalho, Pedro J.; Augusto Q. Pedro. "Bioprocess integration of a membrane protein using aqueous biphasic systems". Paper presented in BPP 2022 - Biopartitioning & Purification Conference, 2022.
  30. Ana M. Ferreira; Ana I. Valente; Castro, Leonor S.; Augusto Q. Pedro; Coutinho, Joao A. P.; Mara G. Freire; Tavares, Ana P. M.. "Aqueous biphasic systems as sustainable liquids support for biocatalytic reactions: Dye enzymatic degradation as a study case". Paper presented in BPP 2022, Biopartitioning & Purification Conference, 2022.
  31. Maria I. Sousa; Mara G. Freire; e Silva, F. A.; Augusto Pedro. "Integrated manufacturing of mRNA nanomedicines using thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in Biopartitioning & Purification Conference, 2022.
  32. Ana F. Pereira; Augusto Q. Pedro; Castro, Leonor S.; Maria J. Quental; Ana P.M.Tavares; Luís C. Branco; Coutinho, Joao A. P.; Fani Sousa; Mara G. Freire. "Purification of RNA using aqueous biphasic systems composed by biocompatible amino acid-based ionic liquids". Paper presented in BPP2022 - Biopartitioning and Purification Conference 2022, 2022.
  33. Magalhães, Flávia F.; Augusto Q. Pedro; Tavares, Ana P. M.; Mara G. Freire. "Recombinante laccase production by Komagataella pastoris". Paper presented in 3º BioIberoAmerica, Ibero-American Congress on Biotechnology, 2022.
  34. Castro, Leonor S.; Sousa, Guilherme; Patrícia Pereira; Neves, Márcia C.; Mara G. Freire; Augusto Q. Pedro. Corresponding author: Sousa, Guilherme. "Improving protein-based biopharmaceuticals downstream process using ionic liquids-based strategies". Paper presented in Jornadas CICECO 2021, 2021.
  35. Castro, Leonor S.; Sousa, Guilherme; Patrícia Pereira; Neves, Márcia C.; Mara G. Freire; Augusto Q. Pedro. Corresponding author: Sousa, Guilherme. "Sustainable ionic-liquid-based strategies for the downstream processing of interferon a-2b from Echerichia coli". Paper presented in II Chemical & Biological Engineering Symposium, 2021.
  36. Castro, Leonor S; Sousa, Guilherme; Patrícia Pereira; Neves, Márcia C.; Mara G. Freire; Augusto Q. Pedro. Corresponding author: Sousa, Guilherme. "Purification of Interferon a-2b using ionic liquid-based technologies.". Paper presented in 4th Doctoral Congress in Engineering, 2021.
  37. Sousa, Guilherme; Castro, Leonor S; Neves, Márcia C.; Augusto Q. Pedro; Mara G. Freire. Corresponding author: Sousa, Guilherme. "Chromatographic-based separation of interferon a-2b using supported ionic liquids.". Paper presented in Jornadas CICECO 2020, 2020.
  38. L. S. Castro, P. Pereira, F. Sousa, J. A. P. Coutinho, A. P. M. Tavares, M. G. Freire, A. Q. Pedro. "Improvement of recombinant proteins purification by the use of ionic liquids as adjuvants in aqueous two-phase systems". Paper presented in MicroBiotec’19 – Congress of Microbiology and Biotechnology. Coimbra, Portugal, 2019.
  39. M. J. Quental, A. Q. Pedro, P. Pereira, M. Sharma, J. A. Queiroz, J. A. P. Coutinho, F. Sousa, M. G. Freire. "Bio-based ionic liquids as integrated extraction-preservation strategies in RNA bioprocessing". Paper presented in ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology, Sitges, Spain, 2019.
  40. M. C. Neves, P. Pereira, A. Q. Pedro, J. C. Martins, T. Trindade, J. A. Queiroz, M. G. Freire, F. Sousa. "Isolation of nucleic acids using novel ionic-liquid-modified stationary phases". Paper presented in ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology, Sitges, Spain, 2019.
  41. A. Q. Pedro, P. Pereira, M. J. Quental, A. P. Carvalho, S. M. Santos, J. A. Queiroz, F. Sousa, M. G. Freire. "Stabilization of recombinant RNA using biological-based ionic liquids". Paper presented in ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology, Sitges, Spain, 2019.
  42. T. Santos, P. Pereira, A. Q. Pedro, J. Dias, A. Viegas, E. J. Cabrita, C. Cruz. "G-quadruplex recognition by the nucleolin protein in prostate cancer cells". Paper presented in PTNMR Meeting, SMASH – Small Molecule NMR Conference, Porto, Portugal, 2019.
  43. R. Carapito, M. Neves, P. Pereira, A. Q. Pedro, J. A. Queiroz, M. G. Freire, F. Sousa. "Ionic liquids-based supports for the separation of nucleic acids". Paper presented in III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship. Covilhã, Portugal, 2019.
  44. T. Santos, P. Pereira, A. Q. Pedro, J. S. Dias, A. Viegas, J. A. Queiroz, E. J. Cabrita, C. Cruz. "Nucleolin/miR-149 complex: A strategy in the target of prostate cancer cells". Paper presented in III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship. Covilhã, Portugal, 2019.
  45. L. S. Castro, M. R. Almeida, P. Pereira, F. Sousa, J. A. P. Coutinho, A. P. M. Tavares, M. G. Freire, A. Q. Pedro. "Aqueous two-phase systems comprising ionic liquids for the extraction of recombinant proteins". Paper presented in XIV Annual CICS-UBI Symposium (Universidade da Beira Interior), Covilhã, Portugal, 2019.
  46. Márcia C. Neves, Patrícia Pereira, Augusto Q. Pedro, João C. Martins, João A. Queiroz, Mara G. Freire, Fani Sousa. "Preparative chromatography of recombinant nucleic acids using ionic liquids as multimodal ligands". Paper presented in National Congress of Biotechnology (BIOTEC), Vigo, Spain, 2019.
  47. L. S. Castro, M. R. Almeida, P. Pereira, F. Sousa, J. A. P. Coutinho, A. P. M. Tavares, A. Q. Pedro, M. G. Freire. "Improving the purification of recombinant proteins by the use of ionic liquids as adjuvants in aqueous two-phase systems". Paper presented in Jornadas CICECO 2019 – Where Science Meets Society (Universidade de Aveiro), Aveiro, Portugal, 2019.
  48. Maria V. Quental, Augusto Q. Pedro, Patrícia Pereira, Mukesh Sharma, João A. P. Coutinho, Fani Sousa, M. G. Freire. "Integrated extraction-preservation strategies for RNA bioprocessing using biobased ionic liquids". Paper presented in Jornadas CICECO 2019 – Where Science Meets Society (Universidade de Aveiro), Aveiro, Portugal, 2019.
  49. MJ Quental, AQ Pedro, P Pereira, M Sharma, Queiroz JA, Coutinho JAP, Sousa F, Freire MG. "Bio-based ionic liquids as extraction-preservation strategies in RNA bioprocessing". Paper presented in ISGC 2019, La Rochelle, France, 2019.
  50. P Pereira, MC Neves, AQ Pedro, I Rodrigues, JC Martins, T Trindade, JA Queiroz, MG Freire, F Sousa. "Separation of nucleic acids using ionic-liquid functionalized macroporous supports". Paper presented in ChemPor 2018 – 13th International Chemical and Biological Engineering Conference, Aveiro, Portugal, 2018.
  51. AQ Pedro, P. Pereira, MJ Quental, AP Carvalho, SM Santos, JA Queiroz, F Sousa, MG Freire. "Biological-based ionic liquids as novel preservation media for recombinant RNA". Paper presented in ChemPor 2018 – 13th International Chemical and Biological Engineering Conference, Aveiro, Portugal, 2018.
  52. Azevedo GM, Valente JFA, Sousa Â, Pedro AQ, Pereira P, Queiroz JA, Sousa F. "Effect of the purification conditions on the p53-pDNA stability and biological activity”". Paper presented in XIII Annual CICS-UBI symposium, Covilhã, Portugal, 2018.
  53. Pedro AQ, Antunes JA, Pereira P, Passarinha LA, Sousa F, Coutinho JAP, Freire MG. "Bioprocessing of interferon alfa 2b using ionic-liquid-based systems". Paper presented in BPP 2017 – Biopartitioning and Purification Conference, Copenhagen, Denmark, 2017.
  54. Barreira M, Pereira P, Pedro AQ, Figueiras R, Sousa F. "Ionic-liquid assisted-purification of pre-miR-29b for delivery in lung cancer cells". Paper presented in XII Annual CICS-UBI Symposium. Covilhã, Portugal, 2017.
  55. Barreira M, Pereira P, Pedro AQ, Freire MG, Figueiras AR, Sousa F. "Pre-miR-29 as a lung cancer therapeutic: improving purity with ionic liquids and delivery with functionalized nanosystems". Paper presented in II International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship. Covilhã, Portugal, 2017.
  56. Duarte DR, Pedro AQ, Maia CJ, Passarinha LA. "Improvement of STEAP1 biosynthesis from Pichia pastoris X33 cells under an optimized feeding strategy". Paper presented in II International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship. Covilhã, Portugal, 2017.
  57. Augusto Pedro, Joana Antunes, Patrícia Pereira, Luís Passarinha, João Coutinho, Mara Freire. "The role of biocompatible ionic liquids in the purification and stabilization of recombinant interferon alpha 2b". Paper presented in 9th Conference on Recombinant Protein Production (RPP9). Dubrovnik, Croatia, 2017.
  58. Pereira P, Pedro AQ, Tomás J, Sousa A, Queiroz JA, Figueiras R, Sousa F. "Intra and Extracellular Pre-miR-29b Purification by an Agmatine monolithic support". Paper presented in 9º Encontro Nacional de Cromatografia & XVI COLACRO. Lisboa, Portugal, 2015.
  59. Pedro AQ, Bonifácio MJ, Queiroz JA, Passarinha LA. "Purification of histidine-tagged human membrane-bound catechol-O-methyltransferase". Paper presented in 9º Encontro Nacional de Cromatografia & XVI COLACRO. Lisboa, Portugal, 2015.
  60. Pereira P, Pedro AQ, Tomás J, Sousa Â, Queiroz JA, Figueiras A, Sousa F. "Polyplexes-mediated delivery of pre-miR-29b for Alzheimer’s disease therapeutics". Paper presented in I International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Endocrinology and Neurosciences. Covilhã, Portugal, 2015.
  61. Pedro AQ, Martins LM, Dias JML, Bonifácio MJ, Queiroz JA, Passarinha, LA. "An artificial neural networks for membrane-bound catechol-O-methyltransferase biosynthesis in mini-bioreactors with Pichia pastoris methanol-induced cultures networks". Paper presented in 8th Conference on Recombinant Protein Production (RPP). Mallorca, Spain, 2015.
  62. Pedro AQ, Martins LM, Dias JML, Bonifácio MJ, Queiroz JA, Passarinha, LA. "Membrane-bound catechol-O-methyltransferase biosynthesis in Pichia pastoris: optimization of the induction phase using artificial neural networks". Paper presented in Protein & Antibody Engineering Summit (PEGS) Europe, Lisboa, Portugal, 2014.
  63. Correia FF, Pedro AQ, Oliveira D, Queiroz JA, Passarinha LA. "Biosynthesis, Purification and Biointeraction of human SCOMT with Parkinson’s disease inhibitors". Paper presented in 16th European Congress on Biotechnology (ECB). Edinburgh, Scotland, 2014.
  64. Pedro AQ, Oppolzer D, Bonifácio MJ, Maia CJ, Queiroz JA, Passarinha LA. "Evaluation of MutS and Mut+ Pichia pastoris strains for membrane-bound COMT biosynthesis". Paper presented in 13' Microbiotec - Portuguese Congress of Microbiology and Biotechnology, 2013.
  65. Pedro AQ, Oppolzer D, Bonifácio MJ, Maia CJ, Queiroz JA, Passarinha, LA. "Evaluation of a MutS and Mut+ Pichia pastoris strains for membrane-bound COMT biosynthesis". Paper presented in Modern biophysical methods for protein-ligand interactions – EMBO practical course, 2013.
  66. Soares R, Ferreira S, Pedro AQ, Gonçalves AM, Bonifácio MJ, Queiroz JA, Maia CJ, Passarinha LA. "Biosynthesis of human membrane-bound catechol-O-methyltransferase optimization using Plackett-Burman central composite rotatable design". Paper presented in 9th European Symposium on Biochemical Engineering Science (ESBES). Istanbul, Turkey, 2012.
  67. Pedro AQ, Bonifácio MJ, Queiroz JA, Maia CJ, Passarinha LA. "Strategies to improve recombinant human membrane protein overexpression for structural, functional and clinical studies". Paper presented in Jornadas sobre Tecnologia e Saúde. Guarda, Portugal, 2012.
Journal article
  1. Pedro, Augusto Q.; Castro, Leonor S.; Coutinho, João A.P.; Freire, Mara G.. "Ionogels as advanced materials for overcoming challenges in wound healing and drug delivery". Nano Materials Science 7 5 (2025): 599-626. https://doi.org/10.1016/j.nanoms.2024.06.010.
    10.1016/j.nanoms.2024.06.010
  2. Magalhães, Flávia F.; Neves, Márcia C.; Pedro, Augusto Q.; Freire, Mara G.; Santos-Ebinuma, Valéria C.; Tavares, Ana P.M.. "Recombinant laccase biosynthesis for efficient polydopamine coating". Biochemical Engineering Journal 212 (2024): 109483. https://doi.org/10.1016/j.bej.2024.109483.
    10.1016/j.bej.2024.109483
  3. Ferreira, Ana M.; Quental, Maria V.; Sharma, Mukesh; Mondal, Dibyendu; Pedro, Augusto Q.; Coutinho, João A.P.; Freire, Mara G.; et al. "Towards the improved monitoring of bacterial infections by the isolation of DNA from human serum using ionic-liquid-based aqueous biphasic systems". Separation and Purification Technology 316 (2023): 123801. https://doi.org/10.1016/j.seppur.2023.123801.
    10.1016/j.seppur.2023.123801
  4. Almeida, Catarina; Pedro, Augusto Q.; Tavares, Ana P. M.; Neves, Márcia C.; Freire, Mara G.. "Ionic-liquid-based approaches to improve biopharmaceuticals downstream processing and formulation". Frontiers in Bioengineering and Biotechnology 11 (2023): http://dx.doi.org/10.3389/fbioe.2023.1037436.
    10.3389/fbioe.2023.1037436
  5. Capela, Emanuel V.; Bairos, Jéssica; Pedro, Augusto Q.; Neves, Márcia C.; Raquel Aires-Barros, M.; Azevedo, Ana M.; Coutinho, João A.P.; Tavares, Ana P.M.; Freire, Mara G.. "Supported ionic liquids as customizable materials to purify immunoglobulin G". Separation and Purification Technology 305 (2023): 122464. http://dx.doi.org/10.1016/j.seppur.2022.122464.
    10.1016/j.seppur.2022.122464
  6. Gonçalves, Ana M.; Pedro, Augusto Q.; Oliveira, Diana M.; Oliveira, Adriana E.; Santos, Marino F. A.; Correia, Márcia A. S.; Queiroz, João A.; et al. "Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase". International Journal of Molecular Sciences 23 20 (2022): 12298. http://dx.doi.org/10.3390/ijms232012298.
    10.3390/ijms232012298
  7. Ana M. Ferreira; Maria V. Quental; Dibyendu Mondal; Augusto Q. Pedro; Coutinho, Joao A. P.; Mara G. Freire. "Isolation of DNA for molecular diagnosis of bacterial infections using aqueous biphasic systems". Green Chemistry (2022):
    Under revision
  8. Gonçalves, A.M.; Sousa, Â.; Pedro, A.Q.; Romão, M.J.; Queiroz, J.A.; Gallardo, E.; Passarinha, L.A.. "Advances in Membrane-Bound Catechol-O-Methyltransferase Stability Achieved Using a New Ionic Liquid-Based Storage Formulation". International Journal of Molecular Sciences 23 13 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85133120009&partnerID=MN8TOARS.
    10.3390/ijms23137264
  9. Pereira, Patrícia; Pedro, Augusto Q.; Neves, Márcia C.; Martins, João C.; Rodrigues, Inês; Freire, Mara G.; Sousa, Fani. "Efficient Isolation of Bacterial RNAs Using Silica-Based Materials Modified with Ionic Liquids". Life 11 10 (2021): 1090. http://dx.doi.org/10.3390/life11101090.
    Published • 10.3390/life11101090
  10. Duarte, D. R.; Barroca-Ferreira, J.; Gonçalves, A. M.; Santos, F. M.; Rocha, S. M.; Pedro, A. Q.; Maia, C. J.; Passarinha, L. A.. "Impact of glycerol feeding profiles on STEAP1 biosynthesis by Komagataella pastoris using a methanol-inducible promoter". Applied Microbiology and Biotechnology 105 11 (2021): 4635-4648. http://dx.doi.org/10.1007/s00253-021-11367-y.
    Published • 10.1007/s00253-021-11367-y
  11. Castro, Leonor S.; Lobo, Guilherme S.; Pereira, Patrícia; Freire, Mara G.; Neves, Márcia C.; Pedro, Augusto Q.. "Interferon-Based Biopharmaceuticals: Overview on the Production, Purification, and Formulation". Vaccines 9 4 (2021): 328. http://dx.doi.org/10.3390/vaccines9040328.
    Open access • Accepted • 10.3390/vaccines9040328
  12. Pereira, Patrícia; Barreira, Maria; Cruz, Carla; Tomás, Joana; Luís, Ângelo; Pedro, Augusto Q.; Queiroz, João A.; Sousa, Fani. "Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes". Pharmaceuticals 13 10 (2020): 314. http://dx.doi.org/10.3390/ph13100314.
    10.3390/ph13100314
  13. Castro, Leonor S.; Pereira, Patrícia; Passarinha, Luís A.; Freire, Mara G.; Pedro, Augusto Q.. "Enhanced performance of polymer-polymer aqueous two-phase systems using ionic liquids as adjuvants towards the purification of recombinant proteins". Separation and Purification Technology 248 (2020): 117051. http://dx.doi.org/10.1016/j.seppur.2020.117051.
    Published • 10.1016/j.seppur.2020.117051
  14. Cruz, Carla; Pedro, Augusto Q.; Carvalho, Josué; Santos, Tiago; Talhada, Daniela; Paiva, Artur; Queiroz, João A.; et al. "Nucleolin as a potential biomarker for canine malignant neoplasia". Research in Veterinary Science (2020): http://dx.doi.org/10.1016/j.rvsc.2020.10.004.
    10.1016/j.rvsc.2020.10.004
  15. Neves, M.C.; Pereira, P.; Pedro, A.Q.; Martins, J.C.; Trindade, T.; Queiroz, J.A.; Freire, M.G.; Sousa, F.. "Improved ionic-liquid-functionalized macroporous supports able to purify nucleic acids in one step". Materials Today Bio 8 (2020): 100086. http://dx.doi.org/10.1016/j.mtbio.2020.100086.
    Published • 10.1016/j.mtbio.2020.100086
  16. Azevedo, G.M.; Valente, J.F.A.; Sousa, A.; Pedro, A.Q.; Pereira, P.; Sousa, F.; Queiroz, J.A.. "Effect of Chromatographic Conditions on Supercoiled Plasmid DNA Stability and Bioactivity". Applied Sciences 9 23 (2019): 5170. http://dx.doi.org/10.3390/app9235170.
    Open access • Published • 10.3390/app9235170
  17. Pedro, Augusto Quaresma; Queiroz, João António; Passarinha, Luís António. "Smoothing membrane protein structure determination by initial upstream stage improvements". Applied Microbiology and Biotechnology 103 14 (2019): 5483-5500. http://dx.doi.org/10.1007/s00253-019-09873-1.
    Published • 10.1007/s00253-019-09873-1
  18. Augusto Pedro; Sabara D M, Dunne JS, Pedro A Q, Trifunovic J, Balogun I I O, Kotlicic O, Serrano A, Kertez, I. "Spectroscopic studies of naproxen and tryptophan immobilized in polyvinyl alcohol". Biotechnology and Food Science 75 1 (2019): Tom 75 Nr 1 (2011):-Tom 75 Nr 1 (2011):. https://eczasopisma.p.lodz.pl/BFS/article/view/9.
    10.34658/BFS.2011.75.1.39-49
  19. Quental, M.V.; Pedro, A.Q.; Pereira, P.; Sharma, M.; Queiroz, J.A.; Coutinho, J.A.P.; Sousa, F.; Freire, M.G.. "Integrated Extraction-Preservation Strategies for RNA Using Biobased Ionic Liquids". ACS Sustainable Chemistry and Engineering 7 10 (2019): 9439-9448. https://pubs.acs.org/doi/10.1021/acssuschemeng.9b00688.
    Published • 10.1021/acssuschemeng.9b00688
  20. Pedro, A.Q.; Gonçalves, A.M.; Queiroz, J.A.; Passarinha, L.A.. "Purification of Histidine-Tagged Membrane-Bound Catechol-O-Methyltransferase from Detergent-Solubilized Pichia pastoris Membranes". Chromatographia 81 3 (2018): 425-434. https://link.springer.com/article/10.1007/s10337-017-3453-5.
    Published • 10.1007/s10337-017-3453-5
  21. Pedro, A.Q.; Pereira, P.; Quental, M.J.; Carvalho, A.P.; Santos, S.M.; Queiroz, J.A.; Sousa, F.; Freire, M.G.. "Cholinium-Based Good's Buffers Ionic Liquids as Remarkable Stabilizers and Recyclable Preservation Media for Recombinant Small RNAs". ACS Sustainable Chemistry and Engineering 6 12 (2018): 16645-16656. https://pubs.acs.org/doi/10.1021/acssuschemeng.8b03900.
    Published • 10.1021/acssuschemeng.8b03900
  22. Pereira, P.; Pedro, A.Q.; Queiroz, J.A.; Figueiras, A.R.; Sousa, F.. "New insights for therapeutic recombinant human miRNAs heterologous production: Rhodovolum sulfidophilum vs Escherichia coli". Bioengineered 8 5 (2017): 670-677. https://www.tandfonline.com/doi/full/10.1080/21655979.2017.1284710.
    Published • 10.1080/21655979.2017.1284710
  23. Pereira P; Pedro AQ; Tomás J; Maia CJ; Queiroz JA; Figueiras A; Sousa F. "Advances in time course extracellular production of human pre-miR-29b from Rhodovulum sulfidophilum". (2016): https://link.springer.com/article/10.1007/s00253-016-7350-x.
    Published • 10.1007/s00253-016-7350-x
  24. Augusto Q. Pedro; Filipa F. Correia; Fátima M. Santos; Guilherme Espírito-Santo; Ana M. Gonçalves; Maria J. Bonifacio; João António de Sampaio Rodrigues Queiroz; Luís A. Passarinha. "Biosynthesis and purification of histidine-tagged human soluble catechol-O-methyltransferase". Journal of Chemical Technology and Biotechnology 91 12 (2016): 3035-3044. https://onlinelibrary.wiley.com/doi/full/10.1002/jctb.4930.
    Published • 10.1002/jctb.4930
  25. Pedro, A.Q.; Pereira, P.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Purification of Membrane-Bound Catechol-O-Methyltransferase by Arginine-Affinity Chromatography". Chromatographia 78 21-22 (2015): 1339-1348. https://link.springer.com/article/10.1007/s10337-015-2970-3.
    Published • 10.1007/s10337-015-2970-3
  26. Pedro, A.Q.; Martins, L.M.; Dias, J.M.L.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "An artificial neural network for membrane-bound catechol-O-methyltransferase biosynthesis with Pichia pastoris methanol-induced cultures". Microbial Cell Factories 14 113 (2015): https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-015-0304-7.
    Open access • Published • 10.1186/s12934-015-0304-7
  27. Martins, L.M.; Pedro, A.Q.; Oppolzer, D.; Sousa, F.; Queiroz, J.A.; Passarinha, L.A.. "Enhanced biosynthesis of plasmid DNA from Escherichia coli VH33 using Box-Behnken design associated to aromatic amino acids pathway". Biochemical Engineering Journal 98 (2015): 117-126. https://www.sciencedirect.com/science/article/pii/S1369703X15000248.
    Published • 10.1016/j.bej.2015.02.001
  28. Pedro, A.Q.; Oppolzer, D.; Bonifácio, M.J.; Maia, C.J.; Queiroz, J.A.; Passarinha, L.A.. "Evaluation of MutS and Mut+ Pichia pastoris Strains for Membrane-Bound Catechol-O-Methyltransferase Biosynthesis". Applied Biochemistry and Biotechnology 175 8 (2015): 3840-3855. https://link.springer.com/article/10.1007%2Fs12010-015-1551-0.
    Published • 10.1007/s12010-015-1551-0
  29. Correia, F.F.; Santos, F.M.; Pedro, A.Q.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.P.. "Recovery of biological active catechol-O-methyltransferase isoforms from Q-sepharose". Journal of Separation Science 37 1-2 (2014): 20-29. https://onlinelibrary.wiley.com/doi/abs/10.1002/jssc.201300977.
    Published • 10.1002/jssc.201300977
  30. Pedro, A.Q.; Soares, R.F.;; Oppolzer, D.;; Santos, F.M.;; Rocha, L.A.;; Gonçalves, A.M.;; Bonifácio, M.J.;; et al. "An Improved HPLC Method for Quantification of Metanephrine with Coulometric Detection". Journal of Chromatography & Separation Techniques 05 02 (2014): http://dx.doi.org/10.4172/2157-7064.1000217.
    Published • 10.4172/2157-7064.1000217
  31. Gonçalves, A.M.; Pedro, A.Q.; Santos, F.M.; Martins, L.M.; Maia, C.J.; Queiroz, J.A.; Passarinha, L.A.. "Trends in protein-based biosensor assemblies for drug screening and pharmaceutical kinetic studies". Molecules 19 8 (2014): 12461-12485. https://doi.org/10.3390/molecules190812461.
    Open access • Published • 10.3390/molecules190812461
  32. Espírito Santo, G.M.; Pedro, A.Q.; Oppolzer, D.; Bonifácio, M.J.; Queiroz, J.A.; Silva, F.; Passarinha, L.A.. "Development of fed-batch profiles for efficient biosynthesis of catechol-O-methyltransferase". Biotechnology Reports 3 (2014): 34-41. https://www.sciencedirect.com/science/article/pii/S2215017X14000083.
    Published • 10.1016/j.btre.2014.05.005
  33. Gonçalves, A.M.; Pedro, A.Q.; Maia, C.; Sousa, F.; Queiroz, J.A.; Passarinha, L.A.. "Pichia pastoris: A recombinant microfactory for antibodies and human membrane proteins". Journal of Microbiology and Biotechnology 23 5 (2013): 587-601. http://www.jmb.or.kr/journal/viewJournal.html?doi=JMB023-05-01.
    Published • 10.4014/jmb.1210.10063
  34. Santos, F.M.; Pedro, A.Q.; Soares, R.F.; Martins, R.; Bonifácio, M.J.; Queiroz, J.A.; Passarinha, L.A.. "Performance of hydrophobic interaction ligands for human membrane-bound catechol-O-methyltransferase purification". Journal of Separation Science 36 11 (2013): 1693-1702. https://onlinelibrary.wiley.com/doi/10.1002/jssc.201300010.
    Published • 10.1002/jssc.201300010
  35. Pedro, A.Q.; Bonifácio, M.J.; Queiroz, J.A.; Maia, C.J.; Passarinha, L.A.. "A novel prokaryotic expression system for biosynthesis of recombinant human membrane-bound catechol-O-methyltransferase". Journal of Biotechnology 156 2 (2011): 141-146. https://www.sciencedirect.com/science/article/pii/S0168165611004925.
    Published • 10.1016/j.jbiotec.2011.08.022
Magazine article
  1. Castro, Leonor S.; Mara G. Freire; Augusto Q. Pedro. "A tecnologia do ADN recombinante aplicada ao desenvolvimento de vacinas, com especial destaque para o contexto da COVID-19", CAPTAR – Ciência e ambiente para todos, 2023, 10.34624/captar.v12i0.32309.
    10.34624/captar.v12i0.32309
  2. Leonor S. Castro, Patrícia Pereira, Mara G. Freire, Augusto Q. Pedro. "Progress in the development of aqueous two-phase systems comprising ionic liquids for the downstream processing of protein-based biopharmaceuticals (Invited)", American Pharmaceutical review, 2019, https://www.americanpharmaceuticalreview.com/Featured-Articles/518305-Progress-in-the-Development-of-Aqueous-Two-Phase-Systems-Comprising-Ionic-Liquids-for-the-Downstream-Processing-of-Protein-Based-Biopharmaceuticals/.

Intellectual property

Patent
  1. Mara Guadalupe Freire Martins; Augusto Quaresma Henriques Pedro; Coutinho, Joao A. P.; Ana Maria Ferreira; Mukesh Sharma; Dibyendu Mondal; Maria João Quental; et al. 2021. "Sistema aquoso bifásico para uso em medicina veterinária, métodos de produção e suas aplicações". Portugal.
    Granted/Issued
  2. Pereira, P.; Mara G. Freire; Fani Sousa; Augusto Q. Pedro. 2019. "Chromatographic Matriz, method and uses thereof".
    Granted/Issued
  3. Augusto Q. Pedro; Mara G. Freire; Patricia Pereira; Márcia C. Neves; João C. Martins; Fani Sousa; João António de Sampaio Rodrigues Queiroz. 2019. "Separação de ácidos nucleicos utilizando líquidos iónicos como ligandos cromatográficos multimodais em matriz macroporosas (PT 110626 A)". Portugal.
    Granted/Issued
Provisional application for patent
  1. 2019. "Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids (Filled WO/2019/175849 A1)".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/11/07 O potencial do ARN mensageiro na medicina moderna: novas tecnologias de produção e aplicações UM OLHAR SOBRE AS TERAPIAS AVANÇADAS: DA INVESTIGAÇÃO À INOVAÇÃO
UBIPHARMA (Faculdade de Ciências da Saúde, Universidade da Beira Interior) (Portugal)
2025/09 Manufacturing, preservation, and delivery of biopharmaceuticals@PATh 3rd Bilateral Workshop Portugal – Slovenia, (Bio) Materials and Processes for Circular Economy
CICECO, Univerisdade de Aveiro
2025/01/31 Manufacturing and preservation of biopharmaceuticals@PATh 2nd Joint Meeting PATh/COMPASS: Integrate, Innovate, Impact
CICECO, Universidade de Aveiro (Aveiro, Portugal)
2024/10/02 Efficient bioprocessing strategies for biopharmaceuticals using alternative solvents and customizable materials 2ª Jornada de Pós-Graduação em Pesquisa Translacional em Fármacos e Medicamentos
FioCruz, Farmanguinhos (Rio de Janeiro, Brazil)
2019/11/22 Improved downstream processing of recombinant proteins using aqueous two-phase systems composed of ionic liquids Protein Engineering & Summit Europe (PEGS Europe)
Cambridge Healthtech Institute (Lisboa, Portugal)
2019/09/10 Downstream processing of recombinant proteins using alternative purification platforms based on ionic liquids ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology
(Sitges, Spain)
2019/07/04 Ionic liquids-based supports for the purification of RNA XIV Annual CICS-UBI Symposium
Centro de Investigação em Ciências da Saúde - Universidade da Beira Interior (Covilhã, Portugal)
2019/06/12 Bioprocessing of recombinant proteins using alternative purification platforms Spanish National Congress of Biotechnology (BIOTEC)
Spanish Society of Biotechnology (Vigo, Spain)
2018/06/09 Circulating nucleolin as a potential biomarker for canine tumors XXIII Meeting of the Portuguese Society Animal Pathology
Universidade de Coimbra (Coimbra, Portugal)
2017/09/24 Functionalization of chromatographic matrices with ionic liquids for RNA purification Biopartitioning and Purification (BPP)
Technical University of Copenhagen (Copenhaga, Denmark)
2017/07/06 Synthesis and characterization of ionic liquid functionalized matrices for RNAs purification XII Annual CICS-UBI Symposium
Centro de Investigação em Ciências da Saúde - Universidade da Beira Interior (Covilhã, Portugal)
2017/05/17 Small RNA stabilization using biocompatible cholinium-based ionic liquids II International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship
Centro de Investigação em Ciências da Saúde - Universidade da Beira Interior (Covilhã, Portugal)
2017/05/17 Novel alternatives for interferon alpha2b purification: chromatography vs ionic liquid aqueous biphasic systems II International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship
Centro de Investigação em Ciências da Saúde - Universidade da Beira Interior (Covilhã, Portugal)
2017/04/06 Modern applications of ionic liquids in biomolecules bioprocessing: a case-study involving small RNA stabilization using cholinium-based ionic liquids (Invited) III Cycle of Conferences in Medicinal and Pharmaceutical Biotechnology
Universidade da Beira Interior (Covilhã, Portugal)
2015/11/10 A biotechnological platform for pre-miRNAs biosynthesis, purification and brain-targeted delivery Microbiotec'15 - Congress of Microbiology and Biotechnology
Universidade de Évora (Évora, Portugal)
2015/07 Biosynthesis, purification and brain-targeted delivery of pre-miR-29b biopharmaceuticals for Alzheimer’s disease X Annual CICS Symposium
Centro de Investigação em Ciências da Saúde (C, Portugal)
2013/07/01 Purification of recombinant human membrane COMT by ionic-exchange chromatography VIII Annual CICS-UBI Symposium
Centro de Investigação em Ciências da Saúde (Covilhã, Portugal)
2012/09/25 A novel prokaryotic expression system for biosynthesis of recombinant human membrane-bound catechol-O-methyltransferase 9th European Symposium on Biochemical Engineering Science (ESBES).
ESBES (Istambul, Turkey)
2012/09/24 Evaluation of human membrane-bound catechol-O-methyltransferase purification by hydrophobic interaction 32nd International Symposium on the Separation of Peptides, Proteins, and Polynucleotides (ISPPP)
(Istambul, Turkey)
2012/02/01 Kinetics of a recombinant form of human membrane-bound Catechol-O-methyltransferase XLII Portuguese Society Pharmacology Reunion
Portuguese Society Pharmacology (Lisboa, Portugal)
2011/07/05 Advances in time-course biosynthesis and solubilisation of MBCOMT from Brevibacillus cells VI Annual CICS-UBI Symposium
Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior (Covilhã, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2026 - Current Injectable Ionogels for precise mRNA delivery and improved site-specific antigen production (2025.04562.BDANA)
Supervisor
 Biotecnologia (PhD)
Universidade de Aveiro, Portugal

Universidade da Beira Interior, Portugal
2025/10 - Current Transdermal mRNA delivery using sustainable keratin-rich materials (FCT-ECIU)
Co-supervisor
 Biotecnologia (PhD)
Universidade de Aveiro, Portugal
2025/10 - Current ADESIVOS À BASE DE SOLVENTES EUTÉTICOS PARA A ENTREGA TRANSDÉRMICA EFICIENTE E NÃO INVASIVA DE VACINAS DE ARN MENSAGEIRO
Supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2025/10 - Current Desenvolvimento de um processo integrado de preservação/clarificação de ARN mensageiro usando sistemas aquosos bifásicos e líquidos iónico
Supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2025 - Current Customized ionic liquid patches for efficient and non-invasive transdermal delivery of messenger RNA vaccines (2024.05338.BDANA)
Supervisor
 Engenharia Química (PhD)
Universidade de Aveiro, Portugal
2023/08 - Current Production and clarification of mRNA vaccines using integrated processes based on thermoreversible aqueous biphasic systems and ionic liquids (2022.11476.BD)
Supervisor
 Biotecnologia
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
2023 - Current Development of an integrated process for the extraction-purification of biosynthesized messenger RNA vaccines (2023.04854.BD)
Supervisor
 Engenharia Química (PhD)
Universidade de Aveiro, Portugal
2021 - Current Downstream processing of therapeutic proteins using hybrid technologies based on aqueous two-phase systems and supported ionic liquids
Co-supervisor
 Engenharia Química (PhD)
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
2021 - 2025 Plataforma integrada para a produção de lacase e polimerização de dopamina utilizando sistemas aquosos bifásicos
Co-supervisor
 Engenharia Química (PhD)
Universidade de Aveiro, Portugal
2022/10 - 2023/07 Melhorias na obtenção de vacinas de ARN mensageiro utilizando processos integrados de produção-clarificação
Supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2023/02 - 2023/06 Estudo das condições de reticulação de fibrilas e a sua aplicação na extração de biomoléculas
Supervisor
 Bioquímica (Degree)
Universidade de Aveiro, Portugal
2023/02 - 2023/06 Development of an integrated process for the production and purification of laccase
Supervisor
 Bioquímica (Degree)
Universidade de Aveiro, Portugal
2023/01 - 2023/06 Produção de biofármacos de ADN minicircular por fermentação
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2022/10 - 2023 RECOMBINANT MEMBRANE PROTEIN PRODUCTION USING INTEGRATED STRATEGIES
Supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2022/03/15 - 2022/06/30 PhD Contract within the scope of I&D IL2BioPro Melhorias no bioprocessamento de proteínas recombinantes utilizando líquidos iónicos (POCI-01-0145-FEDER-030840)
Supervisor
Universidade de Aveiro, Portugal
2022/03/15 - 2022/06/15 Desenvolvimento de estratégias integradas para a recuperação da ciclooxigenase-2 utilizando líquidos iónicos - Master Fellowship (POCI-01-0145-FEDER-030840)
Supervisor
Universidade de Aveiro, Portugal
2022/02 - 2022/06 Novas aplicações de fibrilas proteicas em bioengenharia
Supervisor of Francisco Rocha
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2022/02 - 2022/06 Desenvolvimento de estratégias integradas para a clarificação e purificação de proteínas terapêuticas recombinantes
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2021/04 - 2021/07 Purification of protein-based biopharmaceuticals using thermo-responsive and biocompatible polymers
Supervisor of Hugo Miguel Dores da Silva
 Biotecnologia Medicinal (Degree)
Instituto Politécnico do Porto, Portugal
2021/04 - 2021/07 Integrated recovery-purification strategies of protein-based biopharmaceuticals
Supervisor
 Biotecnologia Medicinal (Degree)
Instituto Politécnico do Porto, Portugal
2021/02 - 2021/07 Inhibition and disaggregation of beta-amyloid fibrils from Alzheimer's disease using ionic liquids
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Inibição e desagregação de fibrilas beta-amilóides da doença de Alzheimer utilizando solventes eutécticos profundos
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2021/02 - 2021/06 Libertação controlada de biofármacos de DNA plasmídico por fibrilas de albumina humana
Supervisor
 Bioquímica (Degree)
Universidade de Aveiro, Portugal
2019 - 2021 Chromatographic bioseparations of therapeutic proteins using ionic-liquid-functionalized silicas
Co-supervisor of Guilherme Lobo e Sousa
Bioquímica (Master)
Universidade de Aveiro, Portugal
2019 - 2020 IL2BioPro: Towards the improvement of recombinant proteins bioprocessing using ionic liquids - Master Fellowship
Supervisor of Leonor Sofia de Oliveira e Castro
2016 - 2017/10/13 Produção e Purificação do Interferão Alfa-2b a partir de Culturas de Escherichia coli Plataformas Alternativas
Co-supervisor of Joana Raquel Amaral Antunes
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2014 - 2015/11/15 Lyophilization and a preliminary thermodynamic characterization of recombinant SCOMT_His6
Co-supervisor of Rúben Miguel Oliveira Coval
 Biotecnologia (Master)
Universidade da Beira Interior, Portugal
2014 - 2015 Reconstituição funcional da isoforma membranar da catecol-O-metiltransferase humana em sistemas não micelares
Supervisor of Maria João Abrantes
 Bioengenharia (Degree)
Universidade da Beira Interior, Portugal
2013 - 2014/07/16 Stabilization of COMT by experimental design approaches
Co-supervisor of Diana Margarida Tavares de Oliveira
 Biotecnologia (Master)
Universidade da Beira Interior, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2025/09/24 - Current Workshop on Innovative Technologies in mRNA Vaccine Manufacturing”, held within the framework of the European Yscript project. (2025/09/24)
Conference (President of the Organising Committee)
 Universidade de Aveiro, Portugal
2022 - Current PATh/IL2BioPro/mVACCIL Workshop “Leading strategies in biopharmaceuticals manufacturing” (2022)
Conference (President of the Organising Committee)
 Universidade de Aveiro, Portugal
2013/12/02 - 2013/12/04 8º Encontro Nacional de Cromatografia (2013/12/02 - 2013/12/04)
Congress (Member of the Organising Committee)
 Universidade da Beira Interior, Portugal
2013/07/01 - 2013/07/02 VIII Annual CICS-UBI Symposium (2013/07/01 - 2013/07/02)
Symposium (Member of the Organising Committee)
 Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2025/07/15 - 2025/07/19 Academia de Verão
Exhibition
 Academia de Verão outreach event
Universidade de Aveiro, Portugal
2019/07/15 - 2019/07/19 Theoretical and Practical course on cell culture
Workshop
 VII Cell Culture and Tissue Engineering Training Course “Beyond the Microscope, culturing life”
Universidade de Coimbra Faculdade de Medicina, Portugal

Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018/01/11 - 2018/01/11 Theoretical course on the application of Good Manufacturing Practices (GMP) rules for (bio)pharmaceutical applications
Symposium
 Good Manufacturing Practices in the Pharmaceutical Industry: how transform rules into productivity tools
Universidade da Beira Interior, Portugal
2013/10/21 - 2013/10/25 Theoretical and Practical course on the synthesis and purification of recombinant proteins, and modern biophysical techniques to study protein-ligand interactions
Workshop
 EMBO Practical course on modern biophysical methods for protein-ligand interactions
Oulun Yliopisto, Finland

EMBO Press, Germany
2012/02/19 - 2012/02/23 Theoretical and Practical Course on Proteomics
Workshop
 Three Day Proteomics Course: From 2DE to protein identification by mass spectrometry
Centro de Ciências do Mar, Portugal
2012/02/13 - 2012/02/17 Theoretical and Practical course on the application of NMR for molecules identification and studying small-molecule-protein interaction
Workshop
 Hands on course, NMR – From theory to practise
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2018/11/07 Molecular Modelling of a novel G-quadruplex structure and its interaction with ligands
(Thesis) Main arguer
 Rui Pedro Abrantes Carrilho (Master)
Universidade da Beira Interior, Portugal
2018/07/20 Novas estratégias de purificação de microRNAs usando líquidos iónicos
(Thesis) Main arguer
 Inês Isabel Dias Rodrigues (Master)
Universidade da Beira Interior, Portugal
2017/11/10 Novas estratégias de purificação de RNAs usando líquidos iónicos
(Thesis) Main arguer
 João Carlos Claudino Martins (Master)
Universidade da Beira Interior, Portugal
2016/11/14 Biosynthesis optimization of STEAP1 protein in Pichia pastoris X33 MUT+
(Thesis) Main arguer
 Margarida Maria Antunes dos Santos (Master)
Universidade da Beira Interior, Portugal
2016/07/13 Isolation and purification of STEAP1 protein fragment in Escherichia Coli cells: a potential target for prostate cancer
(Thesis) Main arguer
 Jorge Daniel Barroca Ferreira (Master)
Universidade da Beira Interior, Portugal
2014 Caracterização biofísica e bioquímica da MBCOMT ligada a um inibidor farmacológico
(Thesis) Main arguer
 Rita Monteiro (Other)
Universidade da Beira Interior, Portugal
2014 Protótipo de uma mitocôndria artificial para aplicação na doença de Alzheimer
(Thesis) Main arguer
 Joana Coelho (Other)
Universidade da Beira Interior, Portugal
2014 Biosíntese, purificação e biointeracção da proteína humana recombinante Tau com inibidores da doença de Alzheimer
(Thesis) Main arguer
 Luís Clara (Other)
Universidade da Beira Interior, Portugal

Association member

Society Organization name Role
2023/01 - Current UAVR-RNA Club Co-founder

Committee member

Activity description
Role 		Institution / Organization
2024 - Current Member of a doctoral thesis monitoring committee (Comissão de Acompanhamento de Tese) at UBI (Covilhã, Portugal). Universidade da Beira Interior, Portugal
2016/09 - Current Member of Scientific Council of Aveiro Institute of Materials (CICECO)/University of Aveiro
Member
 Universidade de Aveiro CICECO, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/09 - Current Laboratory classes of microbial biotechnology Biotecnologia (Licenciatura) Universidade de Aveiro Departamento de Química, Portugal
2021/02 - 2021/06 Laboratory classes of general chemistry. Meteorologia, Oceanografia e Geofísica (Licenciatura) Universidade de Aveiro, Portugal
2017 - 2018 Seminars in Biotechnology (Invited Speaker) Biotecnologia (Mestrado) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2013 - 2016 Biotechnology - Practical (Laboratory) SDS-PAGE Classes Bioquímica (Mestrado) Universidade da Beira Interior, Portugal
2013 - 2016 Biotechnology - Practical (Laboratory) SDS-PAGE Classes Ciências Biomédicas (Mestrado) Universidade da Beira Interior, Portugal
2013 - 2016 Biotechnology - Practical (Laboratory) SDS-PAGE Classes Química Medicinal (Mestrado) Universidade da Beira Interior, Portugal
2012 - 2016 Cellular and Molecular Biology - Practical (Laboratory) Classes Bioengenharia (Licenciatura) Universidade da Beira Interior, Portugal
2012 - 2016 Cellular and Molecular Biology - Practical (Laboratory) Classes Biotecnologia (Licenciatura) Universidade da Beira Interior, Portugal
2012 - 2016 Cellular and Molecular Biology - Practical (Laboratory) Classes Optometria - Ciências da Visão (Licenciatura) Universidade da Beira Interior, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2025/10/03 Workshop on Innovative mRNA Vaccine Technologies Sparks Engaging Discussions CICECO Knowledge Refinery Support Unit

Mentoring / Tutoring

Topic Student name
2017 - 2018 Purification of nucleic acids using macroporous chromatographic matrices modified with ionic liquids; João C. Martins
2012 - 2013 Bacterial production of plasmid DNA biopharmaceuticals; Luís M. C. Martins
2012 - 2013 Chromatographic purification of recombinant proteins and determination of enzymatic activities; Filipa I. F. Correia
2012 - 2013 Recombinant production of proteins; Guilherme M. P. R. Espírito-Santo
2011 - 2012 Chromatographic purification of recombinant proteins and determination of enzymatic activities; Fátima M. Santos
Distinctions

Award

2023 CICECO Young Investigator Award
Universidade de Aveiro CICECO, Portugal
2019 Best short communication "Ionic liquids-based supports for the purification of RNA"
Universidade da Beira Interior, Portugal
2015 Best Oral Communication "Biosynthesis, purification and brain-targeted delivery of pre-miR-29b biopharmaceuticals for Alzheimer’s disease therapy"
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2012 Best Poster Communication "Strategies to improve recombinant human membrane protein overexpression for structural, functional and clinical studies"
Instituto Politécnico da Guarda, Portugal