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Susana Solá graduated in Genetics and Biology, Faculty of Sciences, ULisboa, and received her PhD in Pharmacy, after PhD training at the University of Minnesota, MN, USA. Currently, Solá is Associate Professor with Habilitation in Faculty of Pharmacy, ULisboa (FFUL) and Leader of the Stem Cell Bioenergetics and Neurogeneration Group at iMed.ULisboa, where she aims to clarify the regenerative role of neural stem cells throughout adult life. Her scientific activity was initiated with the study of biochemical and regulatory pathways of programmed cell death in both hepatic and neural cells. Then, with a strong background in cell fate functional studies, she decided to move for the emerging area of neural stem cells biology. Solá has been dedicated in understanding the molecular mechanisms involved in neural stem cell fate, using in vitro and in vivo models, and identifying potential checkpoints and promising molecules that increase the activity of these cells during neuroregeneration. Recently, she has been interested in exploring the relevance of metabolism in inter-organ communication to improve the long-life activity of neural stem cells and, ultimately, ameliorate neuroplasticity in adulthood. Solá´s work granted her several important distinctions, including the Award of the Programa Gulbenkian de Estímulo à Investigação 2005 by Fundação Calouste Gulbenkian, the Medal of Honour LOréal Portugal 2008 for Women in Science by Fundação para a Ciência e a Tecnologia (FCT), LOréal Portugal and the Portuguese National UNESCO Commission (CNU) and the Honourable Mention at 10th Edition of Crioestaminal Award in Biomedicine, by Crioestaminal and Associação Viver a Ciência. Solá is also member of Scientific Societies and European Consortiums, e.g. Vice-director of the Mind-Brain College of Universidade de Lisboa and Member of Governing Board of the Portuguese Society for Stem Cells and Cell Therapies; the International Society for Stem Cell Research; and COST Actions, actively committed in knowledge transfer strategies between scientific and medical communities. In Academia, Solá is the Coordinator of the Doctoral Course on Stem Cell Technologies (since 2019), Regent of several disciplines of the 2nd and 3rd cycle of studies at FFUL, also participating in other Doctoral/Master Programs outside FFUL.
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Identification

Personal identification

Full name
SUSANA ZEFERINO SOLÁ DA CRUZ

Citation names

  • Solá, Susana
  • Solá, S

Author identifiers

Ciência ID
6E11-707D-B0DC
ORCID iD
0000-0003-2036-797X
Researcher Id
M-5251-2013
Scopus Author Id
7004195841

Telephones

Mobile phone
  • 96 475 02 (Personal)
Telephone
  • 217946400 Ext.: 14521 (Professional)

Addresses

  • iMed.ULisboa, Faculdade de Facrmácia, Avenida Prof. Gama Pinto , 1649-003, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2023/07/25
Concluded
 Habilitation Examination in the Pharmacy research area, Cellular and Molecular Biology specialty (Título de Agregado)
Major in Pharmacy, Cellular and Molecular Biology
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014
Concluded
 XIII Course on Laboratory Animal Science - FELASA level C certificate (Diploma de especialização)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Universiteit Utrecht, Netherlands
2001 - 2005
Concluded
 Doutoramento em Farmácia - especialidade Bioquímica (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Modulation of hepatocyte apoptosis by ursodeoxycholic acid: role of nuclear steroid receptors" (THESIS/DISSERTATION)
 Approved by unanimity with honour and distinction.
1994 - 1998
Concluded
 Biologia (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 15/20
Affiliation

Positions / Appointments

Category
Host institution 		Employer
2025/03/01 - Current Organic Unit Sub-director Colégio Mente-Cérebro, Universidade de Lisboa, Portugal
Universidade de Lisboa, Portugal
2024/04/01 - Current Section Coordinator – Stem Cell Science and Technology Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Projects

Contract

Designation Funders
2013/06/01 - 2016/11/30 TRATAR DOENÇAS HEPÁTICAS TENDO COMO ALVO A NECROPTOSE DOS HEPATÓCITOS
HMSP-ICT/0018/2011
Harvard Medical School Department of Cell Biology, United States

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Fundação Calouste Gulbenkian, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/06/01 - 2015/11/30 S-Glutationilação na Doença de Parkinson.
PTDC/NEU-OSD/0502/2012
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012/03/01 - 2015/06/30 NecroPT - Modular da Necroptose no Tratamento de Doenças Hepáticas
PTDC/SAU-ORG/119842/2010
Harvard Medical School Department of Cell Biology, United States

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 4013 - 2011-2012
PEst-OE/SAU/UI4013/2011
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Amaral, Joana; Solá, Susana; Steer, Clifford; Rodrigues, Cecília. "Nuclear Steroid Receptors in Apoptosis". In Modern Insights Into Disease From Molecules to Man; Apoptosis, 115-131. Londres, United Kingdom: Science Publishers, 2010.
    Published • 10.1201/9781439845431-10
Conference abstract
  1. Paulo, SL; Ribeiro-Rodrigues, L; Rodrigues, RS; Mateus, JM; Fonseca-Gomes, J; Diógenes, MJ; Solá, S; et al. "Adult hippocampal neurogenesis and amyloid-ß: reproducibility of a sporadic Alzheimer's disease model (poster presentation)". Paper presented in FENS 2020 Virtual Forum, 2020.
    Published • 10.14293/S2199-1006.1.SOR-.PP5MOIH.v1
  2. Paulo, SP; Rodrigues, RS; Ribeiro, FF; Fonseca-Gomes, J; Shvachiy, L; Coelho, JE; Diógenes, MJ; et al. "Intracerebroventricular injection of Aß1-42 peptide in adult hippocampal neurogenesis". Paper presented in XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, 2018.
  3. Marta B Fernandes; Ribeiro, Maria; Genebra, Tânia; Rodrigues, Cecília; Solá, Susana. "Driving Mitochondrial Bioenergetics Toward Neural Proliferation and Differentiation". Paper presented in MitoPorto – Advances in mitochondrial research International Symposium, Porto, 2017.
    10.1109/vetec.1989.40134
  4. Amaral, JD; Castro, RE; Solá, S; Rodrigues, CMP. "Modulation of the p53 ubiquitin-proteasome degradation pathway by ursodeoxycholic acid.". Paper presented in The International Liver Conference, Copenhagen, 2009.
    Published
  5. Amaral, JD; Castro, RE; Solá, S; Rodrigues, CMP; Steer, CJ. "p53 is a specific molecular target of ursodeoxycholic acid.". Paper presented in The International Liver Conference, Barcelona, 2007.
    Published • 10.1158/1538-7445.am10-595
  6. Castro, RE; Amaral, JD; Solá, S; Kren, BT; Steer, CJ; Rodrigues, CMP. "Differential regulation of cyclin D1 and apoptosis by bile acids in primary rat hepatocyte.". Paper presented in The International Liver Conference, Barcelona, 2007.
  7. Amaral, JD; Castro, RE; Solá, S; Rodrigues, CMP. "Modulation of pro-apoptotic p53 transcriptional targeting by bile acids in primary rat hepatocytes.". Paper presented in The International Liver Conference, Vienna, 2006.
    Published
  8. Castro, RE; Amaral, JD; Borralho, PM; Solá, S; Kren, BT; Steer, CJ; Rodrigues, CMP. "Bile acids differentially regulate cell cycle and apoptosis-related proteins in primary rat hepatocytes.". Paper presented in The International Liver Conference, Vienna, 2006.
    Published
  9. Solá, S; Amaral, JD; Castro, RE; Ramalho, RM; Kren, BT; Steer, CJ; Rodrigues, CMP. "Nuclear steroid receptors modulate cellular trafficking of ursodeoxycholic acid in primary rat hepatocytes.". Paper presented in The International Liver Conference, Paris, 2005.
    Published
  10. Ramalho, RM; Borralho, PM; Solá, S; Castro, RE; Amaral, JD; Rodrigues, CMP. "Modulation of neurotoxicity associated with Alzheimer’s disease-linked amyloid precursor protein mutations by tauroursodeoxycholic acid.". Paper presented in The FEBS Congress, Budapest, 2005.
    Published
  11. Solá, S; Amaral, JD; Castro, RE; Ramalho, RM; Borralho, PM; Kren, BT; Steer, CJ; Rodrigues, CMP. "Nuclear translocation of UDCA via the glucocorticoid receptor is essential for inhibiting TGF-ß1-induced apoptosis of rat hepatocytes.". Paper presented in Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, 2005.
    Published
  12. Rodrigues, CMP; Solá, S; Silva, R.; Diógenes, MJ; Brites, D. "Implication of mitochondria in apoptosis by the action of bilirubin and glycoquenodeoxycholate". 2000.
Conference paper
  1. Rodrigues, CMP; Solá, S; Silva, R.; Diógenes, MJ; Brites, D. "Apoptosis induced by deoxycholic acid, unconjugated bilirubin andamyloid ß-peptide reflects mitochondrial perturbation which may beinhibited by ursodeoxycholic acid". 2000.
    Published • 10.1016/s0168-8278(00)80482-1
Conference poster
  1. n/a. "Solá is author of more than 300 Abstracts Published in Summarized Books of International Congresses (104 oral presentations)". 2023.
  2. Paulo, Sara L; Ribeiro-Rodrigues, Leonor; Rodrigues, Rui S; Mateus, Joana M; Fonseca-Gomes, João; Soares, Rita; Diógenes, Maria J; et al. "Learning from the (ir)reproducibility of an amyloid-ß- induced model of Alzheimer's disease". Paper presented in ISN-APSN 2022 Meeting, 2022.
  3. Solá, Susana; Roxo, Catarina; Oliveira, Raul; Santos, Sónia; Rodrigues, RS; Xapelli Sara. Corresponding author: Solá, Susana. "Metabolic conditioning of neural stem cells to increase the therapeutic potential of their secretome". Paper presented in International Society for Stem Cell Research 2022 Annual Meeting, 2022.
  4. Solá, Susana; Roxo, Catarina; Oliveira, Raul; Siquenique, S; Rodrigues, RS; Xapelli Sara. Corresponding author: Solá, Susana. "Metabolic resetting of neural stem cells to increase the therapeutic potential of their secretome". Paper presented in EMBO Company of Biologists Workshop, 2022.
  5. Paulo, SL; Ribeiro-Rodrigues, L; Rodrigues, RS; Mateus, JM; Fonseca-Gomes, João; Soares, Rita; Diógenes, MJ; et al. "Mind the bias: lessons on the reproducibility of an amyloid-ß-induced Alzheimer’s disease model". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience (SPN2021), 2021.
  6. Roxo, C; Siquenique, S; Rodrigues, RS; Santos, SS; Miranda, Joana P; Xapelli S; Solá, Susana. "Metabolic regulation of neural stem cell secretome to prevent neural stress and depression-like behavior". Paper presented in iMed.ULisboa meeting 2021, 2021.
  7. Santos, SS; Moreira, JB; Costa, M; Rodrigues, RS; Xapelli, S; Solá, S. "The mitochondrial antioxidant Sirtuin3 cooperates with lipid metabolism to safeguard neurogenesis in ageing and depression". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  8. Paulo, SL; Ribeiro-Rodrigues, L; Rodrigues, RS; Mateus, JM; Soares, R; Fonseca-Gomes, J; Diógenes, MJ; et al. "Look before you leap: a perspective on the reproducibility of a sporadic Alzheimer’s disease model and its impact on neurogenesis". Paper presented in 5th Meeting of the Mind-Brain College, Lisbon, Portugal, 2019.
  9. Ribeiro, FF; Ferreira, F.; Rodrigues, RS; Soares, R; Vaz, SH; Solá, S; Mira, H; Sebastião, AM; Xapelli, S. "Postnatal subventricular zone neurogenesis: adenosine A2A receptor endogenous activation is necessary for brain-derived neurotrophic factor-mediated cell proliferation and neuronal differentiation". Paper presented in 11th International Meeting of Portuguese Society for Stem Cells and Cell Therapies, Lisbon, Portugal, 2019.
  10. Ribeiro, FF; Ferreira, F.; Rodrigues, RS; Soares, R; Vaz, SH; Solá, S; Mira, H; Sebastião, AM; Xapelli, S. "Postnatal subventricular zone neurogenesis: adenosine A2A receptors as regulators of brain-derived neurotrophic factor". Paper presented in 1st European Purine Meeting, Santiago de Compostela, Spain, 2019.
  11. Ribeiro, FF; Ferreira, F.; Rodrigues, RS; Soares, R.; Solá, S; Mira, H; Sebastião, AM; Xapelli, S. "Postnatal hippocampal neurogenesis: adenosine A2A receptors as regulators of new neurons formation in the dentate gyrus". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience (SPN), 2019.
  12. Ribeiro, FF; Ferreira, F.; Rodrigues, RS; Soares, R.; Solá, S; Mira, H; Sebastião, AM; Xapelli, S. "Postnatal hippocampal neurogenesis: Regulation by adenosine A2A receptors". Paper presented in Society for Neuroscience (SfN) Meeting 2018, San Diego, CA, USA, 2018.
  13. Xapelli, S; Ribeiro, FF; Ferreira, F.; Rodrigues, RS; Soares, R.; Vaz, SH; Solá, S; Mira, H; Sebastião, AM. "Postnatal subventricular zone neurogenesis: Regulation by adenosine A2A receptors". Paper presented in Society for Neuroscience (SfN) Meeting 2018”, San Diego, CA, USA, 2018.
  14. Paulo, SL; Rodrigues, RS; Ribeiro, FF; Fonseca-Gomes, J; Shvachiy, L; Coelho, JE; Diógenes, MJ; et al. "Aß1-42 peptide intracerebroventricular injection in rat behaviour and hippocampal neurogenesis". Paper presented in 11th FENS Forum of Neuroscience, Berlin, Germany, 2018.
  15. Paulo, SL; Rodrigues, RS; Ribeiro, FF; Fonseca-Gomes, J; Shvachiy, L; Coelho, JE; Diógenes, MJ; et al. "Effect of an intracerebroventricular injection of Aß1-42 peptide on adult hippocampal neurogenesis". Paper presented in Second Annual Meeting of SynaNet H2020, iMM, Lisbon, Portugal, 2018.
  16. Ribeiro, FF; Ferreira, F.; Rodrigues, RS; Soares, R.; Neves-Tomé, R; Assaife-Lopes, N; Santos, TE.; et al. "Adenosine A2A receptors role in postnatal neurogenesis neurite outgrowth". Paper presented in Second Annual Meeting of SynaNet H2020, iMM, Lisbon, Portugal, 2018.
  17. Carreira, ASA; Afonso, MB; Pereira, DM; Marques, Vanda; Solá, S; Rodrigues, CMP. "High-throughput screening system to find molecules that selectively target cancer stem cells". Paper presented in 10th iMed.ULisboa Postgraduate Students Meeting. FFUL, 2018.
  18. Paulo, SL; Rodrigues, RS; Shvachiy, L; Ribeiro, FF; Solá, S; Sebastião, AM; Xapelli, S. "Adult Hippocampal Neurogenesis in a Sporadic Alzheimer's Disease Model". Paper presented in 3rd Meeting of the PhD Students from the Mind-Brain College of the University of Lisbon (Lisboa, Portugal), 2017.
  19. Marta B Fernandes; Ribeiro, Maria Filipe; Genebra, Tânia; Varela, Ana; Rodrigues, Cecília; Solá, Susana. "Tauroursodeoxycholic Acid Drives Mitochondrial Bioenergetics Toward Neural Stem Cell Proliferation". Paper presented in 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2017.
  20. Marta B Fernandes; Ribeiro, Maria Filipe; Genebra, Tânia; Varela, Ana; Rodrigues, Cecília; Solá, Susana. "Tauroursodeoxycholic Acid Enhances Neural Stem Cell Proliferation Through a Metabolic Shift". Paper presented in 3rd Meeting of the PhD students from the Mind-Brain College of the University of Lisbon, 2017.
  21. Marta B Fernandes; Ribeiro, Maria Filipe; Genebra, Tânia; Rodrigues, Cecília; Solá, Susana. "Driving Mitochondrial Bioenergetics Toward Neural Stem Cell Proliferation". Paper presented in 9th iMed.ULisboa Postgraduate Students Meeting and 2nd i3DU Meeting, 2017.
  22. Paulo, SL; Rodrigues, RS; Shvachiy, L; Ribeiro, FF; Solá, S; Sebastião, AM; Xapelli, S. "Neurogenesis in a Rat Model of Sporadic Alzheimer's Disease". Paper presented in redeSAÚDE’s 4th Annual Conference (Lisboa, Portugal), 2017.
  23. Soares, R.; Genebra, T; Ribeiro, MF; Ribeiro, FF; Xapelli, S; Sebastião, AM; Rodrigues, C.; Solá, S. "Tauroursodeoxycholic acid increases mitochondrial biogenesis, neural stem cell pool and early neurogenesis in adult rats". Paper presented in First Annual Meeting of SynaNetH2020, iMM, Lisbon, Portugal, 2017.
  24. Paulo, SL; Rodrigues, RS; Ribeiro, FF; Fonseca-Gomes, J; Shvachiy, L; Solá, S; Sebastião, AM; Xapelli, S. "Adult hippocampal neurogenesis in sporadic Alzheimer’s disease model". Paper presented in 3rd PhD students Meeting of the Mind-Brain College, 2017.
  25. Ribeiro, FF; Soares, R.; Solá, S; Mira, H; Sebastião, AM; Xapelli, S. "Adenosine A2A receptor activation regulates postnatal hippocampal neurogenesis". Paper presented in 2nd PhD students Meeting of the Mind-Brain College, 2017.
  26. Soares, R.; Ribeiro, FF; Xapelli, S; Sebastião, AM; Rodrigues, C.; Solá, S. "Subventicular administration of the bile acid tauroursodeoxycholic acid increases neural stem cell pool and early neurogenesis in the adult brain". Paper presented in 2nd PhD students Meeting of the Mind-Brain College, 2016.
  27. Moura, B; Diógenes, MJ; Fernandes, CC; Pinto-Duarte, A; Solá, S; Rodrigues, CMP; Ribeiro, JA; Sebastião, AM. "BDNF potentiation mechanism induced by adenosine and impact on apoptosis". Paper presented in 2nd Young European Scientist Meeting, Porto, Portugal, 2007.
Edited book
  1. The 11th Edition of the International Meeting of the SPCE-TC: Advances in Stem Cells and Cell Therapies. Frontiers Media SA. 2021.
    10.3389/978-2-88971-321-9
Journal article
  1. Matilde Santos; João A. Ferreira Moreira; Sónia Sá Santos; Susana Solá. "Correction: Sustaining Brain Youth by Neural Stem Cells: Physiological and Therapeutic Perspectives". Molecular Neurobiology (2025): https://doi.org/10.1007/s12035-025-05260-2.
    10.1007/s12035-025-05260-2
  2. Simão, André L.; Sá Santos, Sónia; Ferreira Moreira, João A.; Silva, Francisca; Oliveira, Raúl; Roxo, Catarina; Santos, Matilde; et al. "Depression- and exercise-associated stimuli exert contrasting effects on neural stem cell activity and paracrine signaling". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1871 8 (2025): 167997. https://doi.org/10.1016/j.bbadis.2025.167997.
    10.1016/j.bbadis.2025.167997
  3. Lourenço, Diogo M.; Zavalko, Svitlana; Duarte, Ana Laura; Sá-Santos, Sónia; Mateus, Joana M.; Rodrigues, Rui S.; Miranda-Lourenço, Catarina; et al. "Cannabidivarin mitigates motor and cognitive impairments in a female mouse model of Rett syndrome". Life Sciences 378 (2025): 123846. https://doi.org/10.1016/j.lfs.2025.123846.
    10.1016/j.lfs.2025.123846
  4. Ana Sofia Boasinha; Fernanda Murtinheira; Susana Solá; Cláudio M. Gomes; Federico Herrera. "S100B Mitigates Cytoskeletal and Mitochondrial Alterations in a Glial Cell Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay". Molecular Neurobiology (2025): https://doi.org/10.1007/s12035-025-05057-3.
    10.1007/s12035-025-05057-3
  5. Trigo, Catarina M.; Rodrigues, Joana S.; Camões, Sérgio P.; Solá, Susana; Miranda, Joana P.. "Mesenchymal stem cell secretome for regenerative medicine: Where do we stand?". Journal of Advanced Research 70 (2025): 103-124. https://doi.org/10.1016/j.jare.2024.05.004.
    10.1016/j.jare.2024.05.004
  6. Matilde Santos; João A. Ferreira Moreira; Sónia Sá Santos; Susana Solá. "Sustaining Brain Youth by Neural Stem Cells: Physiological and Therapeutic Perspectives". Molecular Neurobiology (2025): https://doi.org/10.1007/s12035-025-04774-z.
    10.1007/s12035-025-04774-z
  7. João F. Moreira; Susana Solá. "Dynamics of Neurogenic Signals as Biological Switchers of Brain Plasticity". Stem Cell Reviews and Reports (2024): https://doi.org/10.1007/s12015-024-10788-2.
    10.1007/s12015-024-10788-2
  8. Sónia Santos; João Moreira; Márcia Costa; Rui Rodrigues; Ana Sebastião; Sara Xapelli; Susana Solá. "Correction: Santos et al. The Mitochondrial Antioxidant Sirtuin3 Cooperates with Lipid Metabolism to Safeguard Neurogenesis in Aging and Depression. Cells 2022, 11, 90". Cells (2024): https://doi.org/10.3390/cells13151239.
    10.3390/cells13151239
  9. Lourenço, Diogo M.; Soares, Rita; Sá-Santos, Sónia; Mateus, Joana M.; Rodrigues, Rui S.; Moreira, João B.; Vaz, Sandra H.; et al. "Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis". European Journal of Pharmacology 959 (2023): 176079. http://dx.doi.org/10.1016/j.ejphar.2023.176079.
    10.1016/j.ejphar.2023.176079
  10. Sónia Sá Santos; João B. Moreira; Márcia Costa; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli; Susana Solá. "The Mitochondrial Antioxidant Sirtuin3 Cooperates with Lipid Metabolism to Safeguard Neurogenesis in Aging and Depression". Cells (2021): https://doi.org/10.3390/cells11010090.
    10.3390/cells11010090
  11. "Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions". The Ocular Surface 22 (2021): 245-266. http://dx.doi.org/10.1016/j.jtos.2021.09.001.
    10.1016/j.jtos.2021.09.001
  12. Miranda, Joana P.; Solá, Susana. Corresponding author: Miranda, Joana P.. "Editorial: The 11th Edition of the International Meeting of the SPCE-TC: Advances in Stem Cells and Cell Therapies". Frontiers in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.720554.
    10.3389/fcell.2021.720554
  13. Mafalda Ferreira dos Santos; Catarina Roxo; Susana Solá. "Oxidative-Signaling in Neural Stem Cell-Mediated Plasticity: Implications for Neurodegenerative Diseases". Antioxidants 10 7 (2021): 1088-1088. https://doi.org/10.3390/antiox10071088.
    10.3390/antiox10071088
  14. Paulo SL; Ribeiro-Rodrigues L; Rodrigues RS; Mateus JM; Fonseca-Gomes J; Soares R; Diógenes MJ; et al. "Sustained Hippocampal Neural Plasticity Questions the Reproducibility of an Amyloid-ß-Induced Alzheimer's Disease Model.". Journal of Alzheimer's disease : JAD (2021): http://europepmc.org/abstract/med/34151790.
    10.3233/jad-201567
  15. Ribeiro FF; Ferreira F; Rodrigues RS; Soares R; Pedro DM; Duarte-Samartinho M; Aroeira RI; et al. "Regulation of hippocampal postnatal and adult neurogenesis by adenosine A2A receptor: Interaction with brain-derived neurotrophic factor.". Stem cells (Dayton, Ohio) (2021): http://europepmc.org/abstract/med/34043863.
    10.1002/stem.3421
  16. Fernandes MB; Costa M; Ribeiro MF; Siquenique S; Sá Santos S; Martins J; Coelho AV; et al. "Reprogramming of Lipid Metabolism as a New Driving Force Behind Tauroursodeoxycholic Acid-Induced Neural Stem Cell Proliferation.". Frontiers in cell and developmental biology 8 335 (2020): http://europepmc.org/abstract/med/32582686.
    10.3389/fcell.2020.00335
  17. Solá, Susana; Ribeiro MF; Santos AA; Afonso MB; Rodrigues PM; Sá Santos S; Castro RE; Rodrigues CMP; Solá S. "Diet-dependent gut microbiota impacts on adult neurogenesis through mitochondrial stress modulation". Brain Communications 2 2 (2020): fcaa165.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780462/pdf/fcaa165.pdf.
    Published • 10.1093/braincomms/fcaa165
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/07/26 Fueling brain repair metabolic control of neural stem cells XXIX International Symposium on Morphological Sciences
International Symposium on Morphological Sciences (Lisboa, Portugal)
2024/06/19 Regulation of adult neurogenesis: new opportunities for metabolic engineering.
Instituto de Bioengenharia e Biociências (IBB), IST, Tagus Park. (Oeiras, Portugal)
2023/06/12 Core concepts in stem cell regulation and clinical applications. Course – Neural stem cells for therapies: clinical potential. PhD Programe funded by the Europeu ZintegrUJ
Faculty of Pharmacy, Jagiellonian University (Jagiellonian, Poland)
2023/06/05 The secretome of Pax6–deficient microglia secretome shifts neural stem cell fate. COST Action CA18116 ANIRIDIA-NET. - Working Group final meeting
COST Action CA18116 ANIRIDIA-NET. (Veneza, Italy)
2023/05/05 Metabolic regulation of neural stem cells for brain regeneration. International Society for Neurochemistry and the European Society of Neurochemistry - (ESN-ISN) Neurochemistry School 2023
Society for Neurochemistry and the European Society of Neurochemistry
2023/04/17 Metabolic regulation of adult neurogenesis: a microbiome approach. PDBEB Course - ONE HEALTH: A Metabolic Approach from the Cell to Society
PhD Programme in Experimental Biology and Biomedicine, CNC, University of Coimbra (Coimbra, Portugal)
2023/03/20 Core concepts in stem cell regulation and clinical applications. Course – Neural stem cells: perspectives for clinical application in brain regeneration. PhD Programe funded by the Europeu ZintegrUJ
Faculty of Pharmacy, Jagiellonian University (Jagiellonian, Poland)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025 - 2025 Role of Lifestyle in Neuroplasticity and Neurogenesis
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024 - 2024 Role of Nutrition in Adult Neurogenesis
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024 - 2024 How does high-fat diet disturb neuroregeneration? Clues for the role of miR-21 in the brain
Supervisor
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023 - 2023 Stem cells in neurobiology: current perspectives
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023 - 2023 Neural stem cells sensing injury and metabolic stimuli deliver multiple distinct secretor signals: clues for exercise-induced Depression relief
Supervisor
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022 - 2022 Paracrine Regulation of the Neurogenic Niche by Neural Stem Cells
Supervisor
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022 - 2022 The potential therapeutic role of neural stem cells secretome in neurodegeneration: a bioenergetic approach
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 Bioenergetics and metabolism in neural regeneration
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 The impact of adult neurogenesis in mood disorders
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 Bioenergetic Regulation of Neural Stem Cell Secretome: a Novel Therapeutic Opportunity for Neurodegeneration
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2020 Modulation of neural stem cell secretome: a new hope for the treatment of neurodegeneration
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2018 A high-throughput screening system to identify modulators of cancer stem cells and improve chemotherapy sensitization
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2018 Targeting mitochondria-nucleus communication to improve aging-impaired neurogenesis
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2018 Discovering New Molecules for Diagnosis and Non-Toxic Differentiation Therapy in Colorectal Cancer
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2016 Targeting Mitochondria of Neural Stem Cells for Neurodegeneration
Supervisor
 Farmácia (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2025/11/28 - Current MEETING A Mind-Brain Day: Science and Society in Dialogue (2025/11/28)
Conference (President of the Organising Committee)
2024/11/25 - Current 6th Student Meeting of the Mind-Brain College of the University of Lisbon (2024/11/25)
Congress (President of the Organising Committee)
 Universidade de Lisboa, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025 Promoting Spinal Cord Injury Regeneration through the Combination of Stem Cell Secretome and the Omega-3 Fatty Acid Docosahexaenoic acid Jonas de Oliveira Campos (PhD)
Universidade do Minho, Portugal
2025 Use of 3D BrainSpheres to Model Multiple Sclerosis Cristiana Ailine dos Reis Silva (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024 Caracterização lipidómica das MAMs na doença de Alzheimer - impacto da sua modulação no metabolismo neuronal. Tânia Patrícia Dias Fernandes (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023 Characterization and integration of the transcriptional programs downstream Ascl1 and Notch signaling during neurogenesis: investigating a cell-autonomous cross-talk between the two pathways Abeer Heskol (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2023 Pyroptotic Deadly Curse of Neurons in Alzheimer´s Disease – Unravelling theInflammasome pathway Tiago Miguel Garcia Ferreira (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2023 Antioxidant and anti-inflammatory potential of polyphenols and derived metabolites in Parkinson’s disease Hugo Tainha Lopes (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/08 Molecular mechanisms of neural stem cell activation following brain injury in Drosophila melanogaster Anabel Rodriguez Simões (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2022 Sacsin deletion disrupts the response of C6 rat glioblastoma cells to inflammatory cues Mafalda Maria Migueis Bragança (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2022 Regulation of Skeletal Muscle Repair By Mesencephalic Astrocyte-Derived Neurotrophic Factor Neuza Sofia Simões de Sousa (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022 New role of PGC-1a2 and PGC-1a3 isoforms in the control of astrocyte phenotype Margarida João do Rosário Colaço (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022 Targeting Colorectal Cancer Stem Cells via Ferroptosis, a Potential Immunogenic Cell Death Jan Caira Cruz David (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022 Investigating of scopolamine-induced cognitive impairment in a complex cognitive test battery in rats Catarina Francisco Alves Tavares (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 From Hypoxia to Healing Optimizing Stem Cell therapy for Neonatal Hypoxic-lschemic Brain Injury Inês Isabel Pires Serrenho (PhD)
Universidade da Beira Interior, Portugal
2021 Role of adipocyte-derived extracellular vesicles on liver cells in the context of inflammation Margarida Rios da Cruz (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 Targeting the adipose tissue to treat fatty liver: role of TGR5 Daniela Filipa da Silva (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 Exploring the potential of MSC secretome to counteract APAP-induced hepatic injury in vitro Daniela Sofia Nunes Ribeiro (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020 Unfolding hippocampal and hypothalamic plasticity in aging and Alzheimer’s disease-related pathology Sara Raquel Landeira Nabais Paulo (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2020 Searching for a new biomarker for Alzheimer´s disease based on BDNF receptor cleavage Carolina de Almeida Borlido (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019 Mitochondrial adaptations in breast cancer during cell migration: influence of lipids environments and response to Taxanes Ana Patrícia Quintino Lopes (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2019 Thioredoxin reductase inhibitors as potential antitumorals: mercury compounds efficacy in glioma cells Vanessa Sofia Amaral Pires (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 Mammary organoids to study the functional impact of BRCA mutations Catarina Guerra Ferreira (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 Stress response pathways in developmental and neurodegenerative diseases: models, mechanims and therapeutic potential Liliana Patrícia Maciel Almeida (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 Neural stem cell-derived extracellular vesicles as paracrine regulators in the hippocampus Bruno Miguel Macedo Seguro (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Role of Mi-2 in chromatin regulation to regulate neural stem cell fate and life-span in Drosophila melanogaster Ana Margarida Ramalho Venda (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 Epigenetic drivers of genomic instability during neural differentiation João Maria Rodrigues Perlico da Cruz Sabino (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 Metabolic remodeling and quality control mechanisms in Parkinson´s disease Cláudia Maria Carrudo de Deus (PhD)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2013 Effect of BDNF on synaptic and extrasynaptic NMDA currents João Miguel Guerreiro Covita (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2012 IDENTIFICATION OF S-NITROSYLATED PROTEINS IN INJURY-INDUCED NEUROGENESIS ANA SOFIA MAXIMIANO LEITÃO RIBEIRO LOURENÇO (PhD)
Universidade do Algarve, Portugal
2012 REGULATION OF NEUROGENESIS BY CALPAINS: REVELANCE FOR POST-INJURY BRAIN REPAIR VANESSA MENDES MACHADO (PhD)
Universidade do Algarve, Portugal
2011 Gene Regulation by te transcritption factor ZEB1 in Glioblastoma Multiforme Pedro Mota Prego Rosmaninho (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal

Committee member

Activity description
Role 		Institution / Organization
2025/06/01 - Current Member of the Executive Committee, Department of Pharmaceutical Sciences and Medicines.
Member
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Consulting

Activity description Institution / Organization
2025/10/05 - 2025/12/01 Evaluator of the Horizon Europe Framework Programme (HORIZON) – the Marie Sklodowska-Curie Postdoctoral Fellowships (MSCA-PF) . Call: MSCA Postdoctoral Fellowships - European Fellowships (HORIZON-MSCA-2025-PF-01)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/09/05 - Current Celular Biology Ciências Farmacêuticas (Doutoramento) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/20 - Current Advanced Therapies and Regenerative Medicine Ciências Biofarmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
Distinctions

Award

2025 Prémio de Inovação Pedagógica Universidade de Lisboa
Universidade de Lisboa, Portugal
2023 Award for the Best Oral Presentation 2nd Meeting of the Portuguese Network on Extracellular Vesicles
2023 Award for the Best Oral Presentation ETRS & SPCE-TC Joint Meeting 2023
2017 Awardee of the Brain Awareness Week (BAW) project
Dana Foundation, United States

Federation of European Neuroscience Societies, Belgium
2016 Young Investigator’s Projects for Collaborative Cross-Disciplinary Studies
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2013 International Society for Stem Cell Research (ISSCR) Travel Award Recipient
International Society for Stem Cell Research, United States
2008 Medal of Honour L'Oréal Portugal 2008 for Women in Science
Portuguese National UNESCO Commission , Portugal

L'Oréal Portugal , Portugal

Fundação para a Ciência e a Tecnologia, Portugal
2005 Programa Gulbenkian de Estímulo à Investigação 2005
Fundação Calouste Gulbenkian, Portugal
2005 Award for the Best Poster Presentation - 40th Annual Meeting of the European Association for the Study of the Liver, Paris, France.
European Association for the Study of the Liver, Switzerland
2005 Award for the Best Basic Science Work - Portuguese National Congress of Gastroenterology, Albufeira, Portugal.
Sociedade Portuguesa de Gastrenterologia, Portugal
2004 Award for the Best Basic Science Work - Portuguese National Congress of Gastroenterology, Figueira da Foz, Portugal.
Sociedade Portuguesa de Gastrenterologia, Portugal
2003 “President’s Choice” for Best Poster - 54th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, USA.
American Association for the Study of Liver Diseases, United States
2003 Award for the Best Basic Science Work - Portuguese National Congress of Gastroenterology, Porto, Portugal.
Sociedade Portuguesa de Gastrenterologia, Portugal
2002 Best Poster Award, 3rd ESH-UT M.D. Anderson Cancer Center International Conference, Sintra, Portugal.
Banner MD Anderson Cancer Center, United States
2002 Award for the Best Basic Science Work - Portuguese National Congress of Gastroenterology, Vilamoura, Portugal.
Sociedade Portuguesa de Gastrenterologia, Portugal

Other distinction

2021 3rd Edition of the Women in Science Book
Ciência Viva, Portugal
2018 Honourable Mention at 10th Edition of Crioestaminal Award in Biomedicine
Associação Viver a Ciência, Portugal