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Bárbara Guedes earned her undergraduate degree in Biology from the University of Porto's Faculty of Sciences in 2019, followed by a Master's degree in Cellular and Molecular Biology in 2022. During her undergraduate studies, she participated in an internship project within the Phenotypic Evolution group (I3S) under the mentorship of Dr Jorge Vieira and Dr Cristina Vieira, where she identified and characterised chromosomal inversions in Drosophila montana, thereby enhancing her bioinformatics skills. Her academic progression continued with a Master's thesis supervised by Dr Sandra Quinteira and Dr Olga Lage at the Microbial Ecophysiology Lab (LEMUP). This project involved evaluating the microbiological quality and food safety of ready-to-eat oysters, assessing bacterial isolates' susceptibility to clinically relevant antibiotics, searching for antibiotic resistance genes, and identifying members of the Planctomycetota bacterial group, known for their resistance to multiple antibiotics and potential to disseminate resistance genes. Employing diverse methodologies, she developed expertise in data analysis and acquired substantial knowledge in microbiology, molecular biology, and cellular biology. After completing her MSc, Bárbara joined the food industry as an intern at Cogubelo, a company specialising in the cultivation and retail of exotic mushroom species. There, she expanded her understanding of industrial processes, with responsibilities including planning production studies to improve efficiency and reduce costs, conducting sterilisation tests, evaluating packaging solutions, and implementing pest control and hygiene protocols. She also contributed to planning an automated industrial line, conducted market inquiries to optimise quality and price, and ensured adherence to deadlines. During this internship, she supervised a high school student and provided instruction in various laboratory techniques. Bárbara is currently a first-year PhD student in the Microbiology and Biotechnology in Aquaculture (MBAqua) group at the Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto. Her research focuses on sustainable fish vaccination strategies to prevent and manage bacterial infections in aquaculture. Specifically, she develops next-generation oral vaccines employing Bacillus subtilis spores as innovative delivery vehicles (SporoVaccines). Furthermore, she explores the use of molecular adjuvants, a relatively novel approach in oral immunisation, to enhance immune responses and improve vaccine efficacy. By integrating SporoVaccines with molecular adjuvants, her work aims to optimise oral vaccine performance. This innovative strategy advances sustainable aquaculture by reducing antibiotic dependence, enhancing fish welfare, and supporting the production of safe, high-quality products. Bárbara's key scientific and technological achievements include 4peer-reviewed journal publications, 2 of which she authored as first author; 11 oral and poster presentations at national and international conferences; and co-supervision of 3 BSc students, with 2 currently ongoing.
Identification

Personal identification

Full name
Bárbara Alexandra Gaspar Guedes

Citation names

  • Guedes, Bárbara

Author identifiers

Ciência ID
6C11-9B37-F3DB
ORCID iD
0000-0002-6042-4898

Email addresses

  • up201606117@up.pt (Professional)
  • bguedes@ciimar.up.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Marine Biology
  • Agrarian Sciences - Agrarian and Food Biotechnology - Agricultural Biotechnology and Food Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2024/10/01 - 2029/01/01
Ongoing
Programa Doutoral em Biologia (Doutoramento)
Major in Biologia
Universidade do Porto, Portugal
"SporoVaccines: Exploring the potential of ProbioSpores as ORAL VACCINES for Aquaculture" (THESIS/DISSERTATION)
2024/12 - 2024/12
Concluded
CAL-AQUA Laboratory Aquatic Animal Sciences Course (Outros) (Curso de Especialização Tecnológica)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2020/09/01 - 2022/12/16
Concluded
Biologia Celular e Molecular (Mestrado)
Universidade do Porto, Portugal
"Microbiological quality and safety of Pacific oysters (Magallana gigas) ready for consumption" (THESIS/DISSERTATION)
18
2016/09 - 2019/07/08
Concluded
Biologia (Licenciatura)
Universidade do Porto, Portugal
"On the Origin of Chromosomal Inversions in Drosophila montana" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2024/12 - Current Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2023/03 - 2023/12 Research Trainee (Research) Aparência Primaveril Lda., Portugal
2021/07 - 2022/12 Research Trainee (Research) Universidade do Porto Faculdade de Ciências, Portugal
2018/09 - 2021/04 Research Trainee (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Others

Category
Host institution
Employer
2022/01/30 - 2022/01/30 Polling Table of Portuguese Legislatives in 2022 (January 30th, 2022) Governo da República Portuguesa, Portugal
2021/03 - 2021/06 Census Taker - CENSOS 2021 Instituto Nacional de Estatistica, Portugal
Projects

Contract

Designation Funders
2020/01/01 - 2024/12/31 Interdisciplinary Centre of Marine and Environmental Research
UIDB/04423/2020
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Guedes, Bárbara; Gonçalves, Gabriela C.; Santos, Rafaela A.; Couto, Ana; Oliva-Teles, Aires; Serra, Claudia R.. "Fine-tuning Sporovaccines to Improve Oral Immunisation in the Aquaculture Sector". 2025.
  2. Lage, olga; Guedes, Bárbara; Quinteira, Sandra; Godinho, Ofélia. "Avaliação da Qualidade e Segurança Microbiológica de Ostras-do-Pacífico (Magallana gigas) Prontas para Consumo". Paper presented in 17.ª Reunião Anual PortFIR, 2025.
  3. Guedes, Bárbara; Gonçalves, Gabriela C.; Santos, Rafaela A.; Couto, Ana; Oliva-Teles, Aires; Serra, Claudia R.. "Designing Oral Vaccines for Aquaculture: Bacillus Spores and Molecular Adjuvants for Enhanced Mucosal Immunity". Paper presented in Blue Think Conference, 2025.
  4. Guedes, Bárbara; Gonçalves, Gabriela C.; Santos, Rafaela A.; Couto, Ana; Oliva-Teles, Aires; Serra, Claudia R.. "Fine-tuning Sporovaccines to Improve Oral Immunisation in the Aquaculture Sector". Paper presented in Aquaculture Europe 2025, 2025.
  5. Guedes, Bárbara; Gonçalves, Gabriela; Santos, Rafaela; Couto, Ana; Oliva-Teles, Aires; Serra, Cláudia. "Fine-tuning SporoVaccines: Advancing Fish Oral Immunization Strategies for Aquaculture Sustainability". Paper presented in 23rd Fish Immunology / Vaccination Workshop, 2025.
  6. Guedes, Bárbara; Gonçalves, Gabriela C.; Santos, Rafaela A.; Couto, Ana; Oliva-Teles, Aires; Serra, Claudia R.. "Engineering Oral Fish Vaccines: Enhancing Mucosal Immunity by Employing SporoVaccines and Molecular Adjuvants". Paper presented in Microbiotec 2025, 2025.
  7. Guedes, Bárbara; Gonçalves, Gabriela; Santos, Rafaela; Couto, Ana; Oliva-Teles, Aires; Serra, Cláudia. Corresponding author: Guedes, Bárbara. "Enhancing Fish Oral Immunisation: fine-tunning SporoVaccines for Aquaculture". Paper presented in MicroSummit’2024, 2024.
  8. Guedes, Bárbara; Godinho, Ofélia; Lage, olga; Quinteira, Sandra. "Microbiological quality and safety of Pacific Oysters (Magallana gigas) ready for consumption". Paper presented in 15th U.PORTO Young Researchers Meeting (IJUP 2022), 2022.
  9. Guedes, Bárbara; Godinho, Ofélia; Quinteira, Sandra; Lage, olga. "Extending the natural reservoir of Planctomycetota to Pacific oysters". Paper presented in 15th U.PORTO Young Researchers Meeting (IJUP 2022), 2022.
Journal article
  1. Vicente-Gil, Samuel; Morel, Esther; Guedes, Bárbara; Gonçalves, Gabriela; Santos, Rafaela; Nogales-Mérida, Silvia; Serra, Claudia; Díaz-Rosales, Patricia; Tafalla, Carolina. Corresponding author: Tafalla, Carolina. "Bacillus subtilis spores influence the capacity of rainbow trout leukocytes to respond to a posterior viral encounter". Fish & Shellfish Immunology 171 (2026): 111207. https://doi.org/10.1016/j.fsi.2026.111207.
    10.1016/j.fsi.2026.111207
  2. Bárbara Guedes; Ofélia Godinho; Sandra Quinteira; Olga Maria Lage. "Antimicrobial Resistance Profile of Planctomycetota Isolated from Oyster Shell Biofilm: Ecological Relevance within the One Health Concept". Applied Microbiology (2023): http://dx.doi.org/10.3390/applmicrobiol4010002.
    10.3390/applmicrobiol4010002
  3. Godinho, Ofélia; Klimek, Dominika; Jackiewicz, Adrianna; Guedes, Bárbara; Almeida, Eduarda; Calisto, Rita; Vitorino, Inês Rosado; et al. "Stieleria tagensis sp. nov., a novel member of the phylum Planctomycetota isolated from Tagus River in Portugal". Antonie van Leeuwenhoek 116 11 (2023): 1209-1225. http://dx.doi.org/10.1007/s10482-023-01877-2.
    10.1007/s10482-023-01877-2
  4. Bárbara Guedes; Ofélia Godinho; Olga Maria Lage; Sandra Quinteira. "Microbiological quality, antibiotic resistant bacteria and relevant resistance genes in ready-to-eat Pacific oysters (Magallana gigas)". FEMS Microbiology Letters (2023): https://doi.org/10.1093/femsle/fnad053.
    10.1093/femsle/fnad053
Thesis / Dissertation
  1. "Microbiological quality and safety of Pacific oysters (Magallana gigas) ready for consumption". Master, Universidade do Porto Faculdade de Ciências, 2022. https://hdl.handle.net/10216/146880.
  2. "On the Origin of Chromosomal Inversions in Drosophila montana". Degree, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/07 Fine-tuning SporoVaccines: Advancing Fish Oral Immunization Strategies for Aquaculture Sustainability 2nd UPorto Research Summer School in Microbial Communities
Faculty of Engineering – University of Porto (Porto, Portugal)
2022/11 Avaliação da qualidade microbiológica de ostras do pacifico (Magallana gigas) prontas para consumo Microbiologia 2022 Congresso Internacional de Microbiologia em Língua Portuguesa
Sociedade Portuguesa de Microbiologia (Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2025 - 2026 Co-supervision of a student during her final year of the bachelor’s degree in biology internship
Co-supervisor
Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2025 - 2026 Co-supervision of a student during her final year of the bachelor’s degree in biology internship
Co-supervisor
Blue Young Talent CIIMAR (Degree)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2024 - 2025 Co-supervision of a student during her final year of the bachelor’s degree in biology internship
Co-supervisor
Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2017/03/02 - 2017/03/03 Participation in the departmental organization of the FCUP Open Days (2017/03/02 - 2017/03/03)
Exhibition
Universidade do Porto Faculdade de Ciências, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2026 - 2026 Volunteer CIIMAR Stand- Mosta U. Porto 2026
Exhibition
Mostra U. Porto 2026
Universidade do Porto, Portugal
2024/09 - 2024/09 Participation in 3rd International Symposium - MUCOSAL HEALTH IN AQUACULTURE
Conference
Mucosal Health in Aquaculture – MHA2024
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2023/12/15 - 2023/12/15 Inov4Agro, dialogue with stakeholders from the main agricultural value chains in the North region.
Meeting
Inov4Agro
Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade do Porto GreenUPorto Centro de Investigação em Produção Agroalimentar Sustentável, Portugal
2022/10/17 - 2022/10/19 Microbiologia 2022 – International Congress of Microbiology in the Portuguese Language, where young microbiologists discuss their research projects.
Conference
Microbiologia 2022 – Congresso Internacional de Microbiologia em Língua Portuguesa
Sociedade Portuguesa de Microbiologia, Portugal
2022/05/04 - 2022/05/06 15th U.PORTO Young Researchers Meeting (IJUP 2022), debates of the most recent research projects developed by students.
Meeting
15º Encontro de Jovens Investigadores da Universidade do Porto (IJUP 2022)
Universidade do Porto, Portugal
2019/04/12 - 2019/04/12 Genetics in Family Medicine A Genética na Medicina Geral e Familiar
Centro de Genética Preditiva e Preventiva, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/03/12 - 2019/03/12 Semana Internacional do Cérebro 2019 Semana Internacional do Cérebro 2019
Sociedade Portuguesa de Neurociências, Portugal

Mentoring / Tutoring

Topic Student name
2025/07 - 2025/07 Mentor of student during the UPorto Research Summer School Internship Maria Luísa Martins
2023/07 - 2023/12 Tutor Professional Internship High School Student (Colégio Internato dos Carvalhos) Maria Verónica Parasiy
Distinctions

Award

2025 Best poster presentation - 17.ª Reunião Anual PortFIR
PortFIR - Plataforma Portuguesa de Informação Alimentar, Portugal
2022 Honorable mention of oral presentation - International Congress in Portuguese Language - Microbiologia 2022
Sociedade Portuguesa de Microbiologia, Portugal