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Bárbara Guedes obtained her Undergraduate degree in Biology from the University of Porto's Faculty ofSciences in 2019, she further distinguished herself by completing a Master's degree in Cellular and MolecularBiology in 2022. During her undergraduate studies, Bárbara had the opportunity to participate in an internshipproject in the Phenotypic Evolution group (I3S) under the mentorship of Dr. Jorge Vieira and Dr. Cristina Vieira,where she identified and characterised chromosomal inversions in Drosophila montana, expanding herbioinformatics knowledge. Her academic journey continued with a Master's Thesis conducted under thesupervision of Dr. Sandra Quinteira and Dr. Olga Lage at the Microbial Ecophysiology Lab (LEMUP). In thisproject, Bárbara evaluated the microbiological quality and food safety of ready-to-eat oysters, assessed thesusceptibility patterns of bacterial isolates to clinically relevant antibiotics, searched for antibiotic resistancegenes and identified members of the Planctomycetota bacterial group, which are recognised for beingresistant to numerous antibiotics and hence capable of spreading antibiotic resistance genes. Through the useof a variety of methodologies, Bárbara gained expertise in data analysis and gained valuable knowledge in thefields of microbiology, molecular biology, and cellular biology. Following her Msc Bárbara joined the foodindustry by working as a intern at Cogubelo, a company dedicated to the cultivation and retailing of exoticmushroom species. At Cogubelo she expand her understanding of the industrial environment. Herresponsibilities included planning production studies for increased efficiency and cost reduction, conductingsterilization tests, evaluating packaging solutions and implementing pest control and hygiene plans. She alsocollaborated in planning an automated industrial line, conducting market inquiries to ensure optimal quality,price, and deadlines. During her internship, Bárbara undertook the supervision of a high school student, beingresponsible with instructing her various laboratory techniques.Barbara has THREE ARTICLES PUBLISHED IN PEER-REVIEWED INTERNATIONAL JOURNALS, two of which asthe first author. In 2022, she won an honourable mention for her oral presentation at the InternationalCongress of Microbiology in Portuguese language - Microbiologia 2022. Currently, Bárbara is a 1st year PhD student in the Microbiology and Biotechnology in Aquaculture (MBAqua) group at the Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto. Her research is centred on sustainable fish vaccination strategies to prevent and manage bacterial infections in aquaculture. She focuses on the development of next-generation oral vaccines using Bacillus subtilis spores as innovative delivery vehicles (SporoVaccines). Additionally, she investigates the use of molecular adjuvants, a relatively unexplored approach in oral immunization, to boost immune responses and enhance vaccine efficacy. By combining SporoVaccines with molecular adjuvants, her research aims to optimize the performance of oral vaccines. This innovative approach contributes to the advancement of sustainable aquaculture by reducing reliance on antibiotics, improving fish welfare, and supporting the production of safe, high-quality aquaculture products.
Identification

Personal identification

Full name
Bárbara Alexandra Gaspar Guedes

Citation names

  • Guedes, Bárbara

Author identifiers

Ciência ID
6C11-9B37-F3DB
ORCID iD
0000-0002-6042-4898

Email addresses

  • up201606117@up.pt (Professional)
  • bguedes@ciimar.up.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Marine Biology
  • Agrarian Sciences - Agrarian and Food Biotechnology - Agricultural Biotechnology and Food Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2024/10/01 - 2029/01/01
Ongoing
Programa Doutoral em Biologia (Doutoramento)
Major in Biologia
Universidade do Porto, Portugal
"SporoVaccines: Exploring the potential of ProbioSpores as ORAL VACCINES for Aquaculture" (THESIS/DISSERTATION)
2024/12 - 2024/12
Concluded
CAL-AQUA Laboratory Aquatic Animal Sciences Course (Outros) (Curso de Especialização Tecnológica)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2020/09/01 - 2022/12/16
Concluded
Biologia Celular e Molecular (Mestrado)
Universidade do Porto, Portugal
"Microbiological quality and safety of Pacific oysters (Magallana gigas) ready for consumption" (THESIS/DISSERTATION)
18
2016/09 - 2019/07/08
Concluded
Biologia (Licenciatura)
Universidade do Porto, Portugal
"On the Origin of Chromosomal Inversions in Drosophila montana" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2024/12 - Current Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2023/03 - 2023/12 Research Trainee (Research) Aparência Primaveril Lda., Portugal
2021/07 - 2022/12 Research Trainee (Research) Universidade do Porto Faculdade de Ciências, Portugal
2018/09 - 2021/04 Research Trainee (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Others

Category
Host institution
Employer
2022/01/30 - 2022/01/30 Polling Table of Portuguese Legislatives in 2022 (January 30th, 2022) Governo da República Portuguesa, Portugal
2021/03 - 2021/06 Census Taker - CENSOS 2021 Instituto Nacional de Estatistica, Portugal
Outputs

Publications

Conference poster
  1. Guedes, Bárbara; Gonçalves, Gabriela C.; Santos, Rafaela A.; Couto, Ana; Oliva-Teles, Aires; Serra, Claudia R.. "Fine-tuning Sporovaccines to Improve Oral Immunisation in the Aquaculture Sector". 2025.
  2. Lage, olga; Guedes, Bárbara; Quinteira, Sandra; Godinho, Ofélia. "Avaliação da Qualidade e Segurança Microbiológica de Ostras-do-Pacífico (Magallana gigas) Prontas para Consumo". Paper presented in 17.ª Reunião Anual PortFIR, 2025.
  3. Guedes, Bárbara; Gonçalves, Gabriela C.; Santos, Rafaela A.; Couto, Ana; Oliva-Teles, Aires; Serra, Claudia R.. "Designing Oral Vaccines for Aquaculture: Bacillus Spores and Molecular Adjuvants for Enhanced Mucosal Immunity". Paper presented in Blue Think Conference, 2025.
  4. Guedes, Bárbara; Gonçalves, Gabriela; Santos, Rafaela; Couto, Ana; Oliva-Teles, Aires; Serra, Cláudia. "Fine-tuning SporoVaccines: Advancing Fish Oral Immunization Strategies for Aquaculture Sustainability". Paper presented in 23rd Fish Immunology / Vaccination Workshop, 2025.
  5. Guedes, Bárbara; Gonçalves, Gabriela; Santos, Rafaela; Couto, Ana; Oliva-Teles, Aires; Serra, Cláudia. Corresponding author: Guedes, Bárbara. "Enhancing Fish Oral Immunisation: fine-tunning SporoVaccines for Aquaculture". Paper presented in MicroSummit’2024, 2024.
  6. Guedes, Bárbara; Godinho, Ofélia; Lage, olga; Quinteira, Sandra. "Microbiological quality and safety of Pacific Oysters (Magallana gigas) ready for consumption". Paper presented in 15th U.PORTO Young Researchers Meeting (IJUP 2022), 2022.
  7. Guedes, Bárbara; Godinho, Ofélia; Quinteira, Sandra; Lage, olga. "Extending the natural reservoir of Planctomycetota to Pacific oysters". Paper presented in 15th U.PORTO Young Researchers Meeting (IJUP 2022), 2022.
Journal article
  1. Bárbara Guedes; Ofélia Godinho; Sandra Quinteira; Olga Maria Lage. "Antimicrobial Resistance Profile of Planctomycetota Isolated from Oyster Shell Biofilm: Ecological Relevance within the One Health Concept". Applied Microbiology (2023): http://dx.doi.org/10.3390/applmicrobiol4010002.
    10.3390/applmicrobiol4010002
  2. Godinho, Ofélia; Klimek, Dominika; Jackiewicz, Adrianna; Guedes, Bárbara; Almeida, Eduarda; Calisto, Rita; Vitorino, Inês Rosado; et al. "Stieleria tagensis sp. nov., a novel member of the phylum Planctomycetota isolated from Tagus River in Portugal". Antonie van Leeuwenhoek 116 11 (2023): 1209-1225. http://dx.doi.org/10.1007/s10482-023-01877-2.
    10.1007/s10482-023-01877-2
  3. Bárbara Guedes; Ofélia Godinho; Olga Maria Lage; Sandra Quinteira. "Microbiological quality, antibiotic resistant bacteria and relevant resistance genes in ready-to-eat Pacific oysters (Magallana gigas)". FEMS Microbiology Letters (2023): https://doi.org/10.1093/femsle/fnad053.
    10.1093/femsle/fnad053
Thesis / Dissertation
  1. "Microbiological quality and safety of Pacific oysters (Magallana gigas) ready for consumption". Master, Universidade do Porto Faculdade de Ciências, 2022. https://hdl.handle.net/10216/146880.
  2. "On the Origin of Chromosomal Inversions in Drosophila montana". Degree, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/07 Fine-tuning SporoVaccines: Advancing Fish Oral Immunization Strategies for Aquaculture Sustainability 2nd UPorto Research Summer School in Microbial Communities
Faculty of Engineering – University of Porto (Porto, Portugal)
2022/11 Avaliação da qualidade microbiológica de ostras do pacifico (Magallana gigas) prontas para consumo Microbiologia 2022 Congresso Internacional de Microbiologia em Língua Portuguesa
Sociedade Portuguesa de Microbiologia (Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2017/03/02 - 2017/03/03 Participation in the departmental organization of the FCUP Open Days (2017/03/02 - 2017/03/03)
Exhibition
Universidade do Porto Faculdade de Ciências, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/09 - 2024/09 Participation in 3rd International Symposium - MUCOSAL HEALTH IN AQUACULTURE
Conference
Mucosal Health in Aquaculture – MHA2024
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2023/12/15 - 2023/12/15 Inov4Agro, dialogue with stakeholders from the main agricultural value chains in the North region.
Meeting
Inov4Agro
Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade do Porto GreenUPorto Centro de Investigação em Produção Agroalimentar Sustentável, Portugal
2022/10/17 - 2022/10/19 Microbiologia 2022 – International Congress of Microbiology in the Portuguese Language, where young microbiologists discuss their research projects.
Conference
Microbiologia 2022 – Congresso Internacional de Microbiologia em Língua Portuguesa
Sociedade Portuguesa de Microbiologia, Portugal
2022/05/04 - 2022/05/06 15th U.PORTO Young Researchers Meeting (IJUP 2022), debates of the most recent research projects developed by students.
Meeting
15º Encontro de Jovens Investigadores da Universidade do Porto (IJUP 2022)
Universidade do Porto, Portugal
2019/04/12 - 2019/04/12 Genetics in Family Medicine A Genética na Medicina Geral e Familiar
Centro de Genética Preditiva e Preventiva, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/03/12 - 2019/03/12 Semana Internacional do Cérebro 2019 Semana Internacional do Cérebro 2019
Sociedade Portuguesa de Neurociências, Portugal

Mentoring / Tutoring

Topic Student name
2025/07 - 2025/07 Mentor of student during the UPorto Research Summer School Internship Maria Luísa Martins
2024/10 - 2025/07 Co-supervision of a student during her final year of the bachelor’s degree in biology internship Sofia Rafaela Ferreira Pinto
2023/07 - 2023/12 Tutor Professional Internship High School Student (Colégio Internato dos Carvalhos) Maria Verónica Parasiy
Distinctions

Award

2025 Best poster presentation - 17.ª Reunião Anual PortFIR
PortFIR - Plataforma Portuguesa de Informação Alimentar, Portugal
2022 Honorable mention of oral presentation - International Congress in Portuguese Language - Microbiologia 2022
Sociedade Portuguesa de Microbiologia, Portugal