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Helena Isabel Alvites Cavaleiro. Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Ciências da Saúde e Ciências Médicas e da Saúde com ênfase em Ciências da Saúde. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: ''traumatic brain injury''; focal lesion''; ''Mesenchymal Stem Cells''; ''Biomaterials''; ''Hydrogel''; ''gellan gum''; .
Identification

Personal identification

Full name
HELENA ISABEL ALVITES CAVALEIRO
Date of birth
1994/05/06
Gender
Female

Citation names

  • Cavaleiro, Helena

Author identifiers

Ciência ID
691E-1DAD-D06B
ORCID iD
0000-0003-2267-1158

Telephones

Mobile phone
  • 935146923 (Personal)

Addresses

  • Rua da Estação n 333, 4465-129, Sao Mamede de Infesta, Matosinhos, Portugal (Personal)

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Advanced (C1) Upper intermediate (B2)
Education
Degree Classification
2019/02/01 - 2023/02/01
Ongoing
PhD in Applied Health sciences (Doutoramento)
Major in Neurociências
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"''Combinatory use of gellan gum and Mesenchymal Stem Cells to promote traumatic brain injury regeneration''" (THESIS/DISSERTATION)
2019/01/01 - 2019/02
Concluded
Laboratory Animal Course (Curso de doutoramento (conclusão de unidades curriculares))
Universidade do Minho Escola de Medicina, Portugal
2015/09/15 - 2017/11/29
Concluded
MsC in Neurobiology (Mestrado)
Major in Neurociências
Universidade do Porto Faculdade de Medicina, Portugal
"“Is TRPV1 involved in pain and bladder dysfunction in multiple sclerosis? An experimental study in rat.” at the Translation NeuroUrology Research Group under the supervision of Prof. Célia Duarte Cruz, PhD, FMUP – Classified with 18 values (out of 20)." (THESIS/DISSERTATION)
17
2016/01/13 - 2017/02/01
Concluded
Molecular essential biology – Essential practical course (Curso de Especialização Tecnológica)
Major in Biologia Molecular
Universidade do Porto Faculdade de Medicina, Portugal
14
2012/09/14 - 2015/07/22
Concluded
Biochemistry (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
15
Affiliation

Others

Category
Host institution
Employer
2018/01/29 - 2019/01/29 Research fellowship with reference Norte2020NEURO64 Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2022/01/01 - 2023/06/30 Ação molecular do Baclofeno como Promotor da Recuperação Neuronal após Lesão Vertebro-Medular Baclofen molecular Action as a promoter of neuronal recovery after Spinal Cord Injury.
EXPL/MED-FAR/1529/2021
Researcher
Outputs

Publications

Journal article
  1. Cavaleiro, Helena; Francesca Pischiutta; Enrico Caruso; Francesca Tribuzio; Noemi Di Marzo; Federico Moro; Firas Kobeissy; et al. "A novel organotypic cortical slice culture model for traumatic brain injury: molecular changes induced by injury and mesenchymal stromal cell secretome treatment". Front Cell Neurosci . (2023): https://pubmed.ncbi.nlm.nih.gov/37534042/.
    Published
  2. Francesca Pischiutta; Enrico Caruso; Cavaleiro, Helena; Antonio SALGADO; David Loane; Elisa R. Zanier. "Mesenchymal stromal cell secretome for traumatic brain injury: Focus on immunomodulatory action". Exp Neurol (2022): https://pubmed.ncbi.nlm.nih.gov/35952763/.
    Published
  3. Francesca Pischiutta; Enrico Caruso; Alessandra Lugo; Helena Cavaleiro; Nino Stocchetti; Giuseppe Citerio; António Salgado; Silvano Gallus; Elisa R. Zanier. "Systematic review and meta-analysis of preclinical studies testing mesenchymal stromal cells for traumatic brain injury". npj Regenerative Medicine (2021): https://doi.org/10.1038/s41536-021-00182-8.
    10.1038/s41536-021-00182-8
  4. Rocha, Luís A.; Silva, Deolinda; Barata-Antunes, Sandra; Cavaleiro, Helena; Gomes, Eduardo D.; Silva, Nuno A.; Salgado, António J.. "Cell and Tissue Instructive Materials for Central Nervous System Repair". Advanced Functional Materials (2020): 1909083. http://dx.doi.org/10.1002/adfm.201909083.
    Published • 10.1002/adfm.201909083
  5. Oliveira, Raquel; Chambel, Sílvia; Cavaleiro, Helena; Cruz, Célia. "Botulinum toxin A in the treatment of bladder dysfunction after spinal cord injury: beyond SNAP 25 cleavage". Frontiers in Cellular Neuroscience 13 (2019): http://dx.doi.org/10.3389/conf.fncel.2019.01.00011.
    Published • 10.3389/conf.fncel.2019.01.00011
  6. Coelho, Ana; Charrua, Ana; Oliveira, Raquel; Cavaleiro, Helena; Cruz, Célia D.; Cruz, Francisco. "Underactive bladder in aging rats is associated with a reduced number of serotonin-expressing cells in the urethra and is improved by serotonin application to the urethra". LUTS: Lower Urinary Tract Symptoms 11 4 (2019): 248-254. http://dx.doi.org/10.1111/luts.12273.
    Published • 10.1111/luts.12273
  7. Coelho, Ana; Oliveira, Raquel; Cavaleiro, Helena; Cruz, Celia Duarte; Cruz, Francisco. "Evidence for an urethro-vesical crosstalk mediated by serotonin". Neurourology and Urodynamics 37 8 (2018): 2389-2397. http://dx.doi.org/10.1002/nau.23590.
    Published • 10.1002/nau.23590
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022 Development of an ex vivo model of Traumatic brain injury to evaluate the therapeutic efficacy of Mesenchymal Stromal cells derived secretome", International Meeting of the Portuguese Society for Stem Cells and Cell Therapies,
ICVS, Braga, Portugal, 2022 (Braga, Portugal)
2022 Development of an in vitro model of traumatic brain injury: a new platform to test protective effects of mesenchymal stromal cells derived secretome INTS - International Neurotrauma Symposium
(Berlin, Germany)
2021/12/02 Development of an ex vivo model of traumatic brain injury to evaluate the therapeutic efficacy of mesenchymal stromal cells derived secretome SPN 2021
Coimbra (Coimbra, Portugal)
2021/03/05 Development of a physiologically relevant ex vivo model of traumatic brain injury to study compounds targeting injury progression The BRAIN Conference 2021
Virtual conference (London)
2018/08/28 “Bladder dysfunction treatment in an animal model of multiple sclerosis” International Continence Society 2018
(Philadelphia, United States)
2017/11/10 "Transient receptor potential vanillin 1 as a therapeutic target for multiple sclerosis" 6th i3S Annual Meeting
i3S (Póvoa de Varzim, Portugal)
2017/11/09 Bladder administration of botulinum toxin during the spinal shock improves urinary dysfunction as a consequence of spinal cord injury". I3S annual meeting
i3s (Póvoa de Varzim, Portugal)
2017/09/14 "Pain and bladder dysfunction in an animal model of multiple sclerosis" 12th YES meeting
Faculty of medicine of Porto (Porto, Portugal)
2017/08/02 "Is TRPV1 involved in pain and bladder dysfunction associated with multiple sclerosis? An experimental study in rat". 10th IJUP eddition
Faculty of Medicine of Porto (Porto, Portugal)
2017/05/27 "Is TRPV1 involved in pain and bladder dysfunction associated with multiple sclerosis? An experimental study in rat". XV meeting of the Portuguese society for neuroscience
Life and Health Sciences Research Institute (ICVS) School of Health Sciences University of Minho Braga and ICVS/3B’s (Braga, Portugal)
2014/05/08 "Study of immunohistochemistry expression of Fibroblast growth factor (FGF-2) in normal uterus and endometrial adenocarcinomas in cat" UTAD veterinarian conference
UTAD (Vila Real, Portugal)
Distinctions

Award

2021 EMBO short term fellowship