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Maria Vasconcelos-Cardoso is currently a PhD student enrolled in the Health Sciences Program at the Faculty of Medicine of the University of Coimbra (FMUC), after being awarded a fully-funded FCT PhD grant (2021.07080.BD). In 2020, completed her MSc degree in Biomedical Research at FMUC, after her BSc degree in Biochemistry at NOVA School of Science and Technology of the NOVA University of Lisbon in 2018. During an internship at the Institute of Hygiene and Tropical Medicine for the final project of the BSc degree, Maria worked with genetic and biochemical tools, a work that culminated in two posters and a conference paper published. During her master thesis, she focused on the mechanisms whereby cells repair their plasma membrane in the context of cardiovascular diseases, with an emphasis on the role of deubiquitylating enzymes. This work was developed in the Group of Ubiquitin-dependent proteolysis and Intercellular Communication (GUIC) led by Henrique Girão, being the main goal of the group the elucidation of how the mechanisms of ubiquitin-dependent lysosomal degradation and intercellular communication either by gap junctions or extracellular vesicles, contribute to cardiovascular diseases, such as myocardial infarction. In 2021, Maria was awarded a grant from the European Cooperation in Science and Technology (COST) within the Cardioprotection Action to perform a Short-Term Scientific Mission (STSM) at Cardiovascular Diseases Research Group led by Antonio Rodríguez-Sinovas, at Vall d'Hebron Institute of Research (VHIR) in Barcelona, Spain. In this group, she had the opportunity to participate in different studies using the Langendorff-perfused isolated heart mice model to assess cardiac pathophysiology. Maria participated in national and international congresses. Importantly, she was invited to present the work developed during her STSM at the international 7th EU-Cardioprotection COST Action WG Online Workshop/Meeting, and her exceptional communication skills were further recognized with the Best Graphical Abstract (2024) and Best Flash Talk (2025) awards, both attributed by the Center for Innovative Biomedicine and Biotechnology (CIBB). Her research outputs include peer-reviewed publications in international and national journals, such as Trends in Biochemical Sciences (2025), Journal of Cell Science (2022), and Revista Portuguesa de Cardiologia (2022, 2023). Beyond her research, Maria has been involved in science outreach activities, such as the European Researchers' Night, as well as in the training of pre-graduated students, having successfully co-supervised 3 MSc students to completion. Demonstrating strong leadership and commitment to institutional service, she also served for two years on the organizing committee of the "PhDoing" event and is actively involved in organizing the community health initiative "PicNic com Saúde", now in its 4th edition.
Identification

Personal identification

Full name
Maria Vasconcelos-Cardoso

Citation names

  • Vasconcelos-Cardoso, Maria

Author identifiers

Ciência ID
6812-3DF1-A5C8
ORCID iD
0000-0002-8812-9380

Addresses

  • Azinhaga de Santa Comba, Celas, 3000-548, Coimbra, Coimbra, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2021/09 - 2025
Ongoing
Health Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Unveil the role of Cx43 in the crosstalk between the tumor and the heart" (THESIS/DISSERTATION)
2023/12/01 - 2023/12/05
Concluded
3rd RESETageing Training School on Quantitative Confocal Microscopy (Outros)
Universidade de Coimbra, Portugal

Newcastle University, United Kingdom

Universiteit Maastricht, Netherlands

Leibniz Institut für Altersforschung - Fritz-Lipmann Institut eV, Germany
2022/09/12 - 2022/09/15
Concluded
2nd RESETageing Training School on Single cell techniques in senescence and ageing (Outros)
Universidade de Coimbra, Portugal

Newcastle University, United Kingdom

Universiteit Maastricht, Netherlands

Leibniz Institut für Altersforschung - Fritz-Lipmann Institut eV, Germany
2021/06/07 - 2021/06/10
Concluded
1st RESETageing Training School on Gene and Proteomic analysis (Outros)
Universidade de Coimbra, Portugal

Newcastle University, United Kingdom

Universiteit Maastricht, Netherlands

Leibniz Institut für Altersforschung - Fritz-Lipmann Institut eV, Germany
2018 - 2020/12/16
Concluded
Biomedical Research (Mestrado)
Major in Infeção e Imunidade
Universidade de Coimbra Faculdade de Medicina, Portugal
"Unveiling the role of deubiquitylating enzymes in plasma membrane repair" (THESIS/DISSERTATION)
18
2015 - 2018
Concluded
Biochemistry (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Produção do Fator de Necrose Tumoral Alfa recombinante e aplicação e caracterização de péptidos recombinantes para a sua deteção" (THESIS/DISSERTATION)
16
Affiliation

Others

Category
Host institution
Employer
2022/01/01 - Current Colaboradora do Laboratório de Comunicação em Saúde Universidade de Coimbra Faculdade de Medicina, Portugal
2021/02/22 - 2021/07/30 Volunteer on Group of Ubiquitin-dependent proteolysis and Intercellular Communication (GUIC) Centre for Innovative Biomedicine and Biotechnology, Portugal
2021/01/18 - 2021/02/19 Fellowship on Cardiovascular Diseases Research Group Vall d'Hebron Institut de Recerca, Spain
Projects

Grant

Designation Funders
2021/10/01 - Current Extracellular vesicles deliver a message from myocardial infarction to cancer
PhD Student Fellow
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2020/01/01 - 2024/12/31 Centro de Inovação em Biomedicina e Biotecnologia
UIDP/04539/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2025 - Current MicroRNA-133 na Vascularização Tumoral do Cancro do Colo do Útero: Biomarcador Preditivo de Resposta à Terapêutica Citostática, Antiangiogénica e à Imunoterapia
x
Researcher
Unidade Local de Saúde de Coimbra, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
Unidade Local de Saúde de Coimbra
Ongoing
2023 - Current The role of Glucagon-like Peptide-1 on dysregulated autophagy in Diabetic Kidney Disease: Implications for Pathogenesis and Therapeutic Strategies
X
Researcher
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
Unidade Local de Saúde de Coimbra
Ongoing
2022 - Current Erasmus+ Project LOLit (Low Literacy at Play)
x
Other
Concluded
Outputs

Publications

Conference paper
  1. Mendonça, Ana; Maria Vasconcelos-Cardoso; Cardoso, Fernando. "Cloning and expression of a recombinant tumor necrosis factor-a (TNF-a) protein". Paper presented in 3rd International Congress of CiiEM, 2018.
    Published • 10.1080/07853890.2018.1561799
Conference poster
  1. Vasconcelos-Cardoso, Maria; Aasen, Trond; Marta Consegal; Rodríguez-Sinovas, Antonio; Martins-Marques, Tânia; Girao, Henrique. "The role of Cx43 in cancer-associated cardiac dysfunction". Paper presented in SINAL2025 - 12th Meeting on Signal Transduction, 2025.
  2. Menino, Rita; Ribeiro-Rodrigues, Teresa M; Vasconcelos-Cardoso, Maria; Girao, Henrique. "The impact of breast cancer-derived EVs on endothelial cells". Paper presented in 3rd Meeting of the Portuguese Network on Extracellular Vesicles, 2025.
  3. Menino, Rita; Ribeiro-Rodrigues, Teresa M; Vasconcelos-Cardoso, Maria; Girao, Henrique. "The impact of breast cancer-derived extracellular vesicles and secretomes on entothelial cells". Paper presented in VIII iBiMED Symposium: Biomedicine Beyond Boundaries, 2025.
  4. Vasconcelos-Cardoso, Maria; Martins-Marques, Tânia; Korolchuk, Viktor; Girao, Henrique. "mTOR activation upon environmental stimulus is dependent on connexin 43". Paper presented in SINAL2024, 2024.
  5. Vasconcelos-Cardoso, Maria; Aasen, Trond; Martins-Marques, Tânia; Girao, Henrique. "Cardiomyocytes-derived extracelular vesicles modulate tumorigenic features.". Paper presented in International Gap Junction Conference. A Coruña, Spain, 2022.
  6. Vasconcelos-Cardoso, Maria; Ana Mendonça; Fenando Cardoso. "Isolation of recombinant peptides ligands against Tumor necrosis factor-a (TNF-a) protein". Paper presented in 3rd International Congress of CiiEM, 2018.
  7. Ana Mendonça; Vasconcelos-Cardoso, Maria; Fernando Cardoso. "Cloning and expression of a recombinant Tumor necrosis factor-a (TNF-a) protein". Paper presented in 3rd International Congress of CiiEM, 2018.
Journal article
  1. Martins-Marques, Tania; Vasconcelos-Cardoso, Maria; Geli, Maria Isabel; Aasen, Trond; Kwak, Brenda R.; Girao, Henrique. "The ins and outs of connexins and pannexins beyond the cell surface". Trends in Biochemical Sciences 50 7 (2025): 622-635. https://doi.org/10.1016/j.tibs.2025.04.005.
    10.1016/j.tibs.2025.04.005
  2. Vasconcelos-Cardoso, Maria. "A new path to preventing sepsis-induced cardiac dysfunction". Revista Portuguesa de Cardiologia (2023): http://dx.doi.org/10.1016/j.repc.2023.06.005.
    10.1016/j.repc.2023.06.005
  3. Maria Vasconcelos-Cardoso; Daniela Batista-Almeida; Laura Valeria Rios-Barros; Thiago Castro-Gomes; Henrique Girao. "Cellular and molecular mechanisms underlying plasma membrane functionality and integrity". Journal of Cell Science (2022): https://doi.org/10.1242/jcs.259806.
    10.1242/jcs.259806
  4. Vasconcelos-Cardoso, Maria; Girao, Henrique. "A new weapon in the armamentarium to tackle inflammation associated with myocardial infarction". Revista Portuguesa de Cardiologia (2022): http://dx.doi.org/10.1016/j.repc.2022.01.002.
    10.1016/j.repc.2022.01.002
Thesis / Dissertation
  1. Vasconcelos-Cardoso, Maria. "Unveiling the role of deubiquitylating enzymes in plasma membrane repair". Master, Universidade de Coimbra Faculdade de Medicina, 2020.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/09 Unveil the role of Cx43 in the crosstalk between the tumor and the heart International Colloquium on “Gap junctions and Cancer”
University of Poitiers (Poitiers, France)
2023/05 Do coração para o tumor PhDoing - Hoje Ciência, Inovação Amanhã!
Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2021/03/11 Use of isolated heart preparations to assess cardiac pathophysiology 7th EU-CARDIOPROTECTION COST Action WG Online Workshop/Meeting

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/09/01 - 2025/10/24 Unravelling the effects of cancer-derived extracellular vesicles on endothelial cells
Co-supervisor
Master in Biomedical Research (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023/09/01 - 2024/10/21 Identification od deubiquitinating enzymes involved in lysosomal damage and strategies for its repair
Co-supervisor
Biomedical Research (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022/09/01 - 2024/07 Unveil the role of Connexin43 in cancer-associated cardiac dysfunction
Co-supervisor
Biomedical Research (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019/09 - Current European Researcher's Night (2019/09)
Other
Universidade de Coimbra Faculdade de Medicina, Portugal
2024/06/05 - 2024/06/06 PhDoing - Da Pipeta ao Estetoscópio! (2024/06/05 - 2024/06/06)
Conference (Co-organisor)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023/05/26 - 2023/05/27 PhDoing - Hoje Ciência, Inovação Amanhã! (2023/05/26 - 2023/05/27)
Conference (Co-organisor)
Universidade de Coimbra Faculdade de Medicina, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/05/24 - 2024/05/25 Meeting SINAL2024
Conference
2021/03/11 - 2021/03/11 7th EU-CARDIOPROTECTION COST Action WG Online Workshop/Meeting
Meeting
2019/05/15 - 2019/05/17 XLV SPI Annual Meeting 2019
Conference
2018/06/20 - 2018/06/22 3rd International Congress of CiiEM
Congress

Mentoring / Tutoring

Topic Student name
2019/09 - Current Scientific tutoring of one pre-graduated student Integrated Master degree in Medicine, FMUC
Distinctions

Award

2025 Best Flash Talk.
Centre for Innovative Biomedicine and Biotechnology, Portugal
2024 Best Graphical Abstract
Centre for Innovative Biomedicine and Biotechnology, Portugal

Other distinction

2022 RESETageing Mission
2021 Short-Term Scientific Mission (STSM) Grant
European Cooperation in Science and Technology, Belgium