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Luisa Pinto started her research work at the Karolinska Institute, where she did an internship on the subject of stem cells as a therapeutical tool for Parkinson Disease with Prof. Ernest Arenas and Dr. Gonçalo Castelo-Branco, experts in stem cells and regenerative therapies. She went then to the Helmholtz Zentrum München, Germany, to do her PhD in Neurosciences entitled "Molecular mechanisms regulating neurogenesis in the developing mouse cortex, under the supervision of the highly recognized expert in stem cells and neurogenesis", with Dr. Magdalena Goetz. In 2008, Luísa got a post-doctoral position in the lab of Prof. Nuno Sousa, at the Life and Health Sciences Research Institute (ICVS), University of Minho, Portugal. Luísa was an Assistant Investigator (FCT Investigator Grant; 2015-2020) and Assistant Researcher (FCT CEEC position) at ICVS in 2021. She is now Principal Researcher with tenure at ICVS (since March 2024) and Team Coordinator of the ¿Brain circuits and neuron-glia adaptations¿ tematic line at ICVS. Since February 2023, she is also member of the Direction of ICVS as elected representative of the team coordinators of the Institute. She is also Assistant Professor of the Medicine Course at the School of Medicine, University of Minho (since 2009). She is also business partner of a start-up company BNML - Behavioral & Molecular Lab. She is also a Co-Founder Member of the European College of NeuroPsychopharmacolgy (ECNP) Thematic Network on Resilience. Luísa Pinto has published more than 80 articles with an accumulated impact factor of 528 (average impact factor of 7; h-index=31), including in top journals such as Nature Neuroscience, Neuron, Molecular Psychiatry and Cell Stem Cell. Her work has above 3000 citations. She is currently supervising 1 Junior Researcher, 1 Post-Doc, 8 PhD and 1 MSc students. Moreover, 1 Post-doc, 12 PhD and 20 MSc students already finished their degree under her supervision. She is invited for peer-reviewing for Journals such as Nature, Molecular Psychiatry, Neuroscience, Frontiers, British Journal of Pharmacology, Neuropharmacology, Molecular Neurobiology and is editor-in chief of the journals BOSN (Brain Organoids and Systems Neurosciences Journal). She is also Review Editor in Neurogenesis for Frontiers in Neuroscience and Associate Editor in Neurodegeration for Frontiers in Neuroscience, Frontiers in Neurology and Frontiers in Psychiatry. Luísa has one patent (nº105555; 2011) from a new protocol entitled: Immuno-Golgi as a tool for analyzing neuronal 3D-dendritic structure in phenotypically charaterized neurons; and 2 registered European Patents (20167348.0-1118 and 20166914.0-1112; 2020). Luisa has been a project reviewer for the University of Bordeaux Postdoctoral IdEx Programme of Excellence, for the French National Research Agency (ANR), ERA-NET NEURON on Mental Disorders, Research Foundation Flanders and Graduate Women in Science (GWIS) and FCT. She was recently awarded with a runner up Nature Research Award for Driving Global Impact: 2019 Brain Sciences and with the highly competitive Portuguese government FCT CEEC Assistant Researcher position (8% approval rate) in 2020. She gained scientific management experience by coordinating FCT-funded projects (50.000eur+268.4113eur for salaries- 2015-2020 and 250.000eur - 2023-2026), a Bial-funded project (48.000eur; 2015-2020), a Santa Casa Mantero Belard Prize for Neurodegenerative Diseases (200.000eur; 2020-2022; Co-PI), pharma-sponsored projects (total 300.000eur) and an EU-funded H2020 ITN-Network (3,750,899eur; 2017-2021; Local Coordinator). Luisa Pinto's main research interests are currently focused in the establishment of functional and structural correlations mediated by stress and its implications in depression. Maternity: First maternity leave: from 08/03/2011 until 05/07/2011; Medical leave due to risky pregnancy: from 03/02/2020 until 24/06/2020; Second maternity leave: from 25/06/2020 until 21/11/2020
Read full resume ↓
Identification

Personal identification

Full name
Luisa Pinto
Date of birth
1981/03/10
Gender
Female

Citation names

  • Pinto, Luisa

Author identifiers

Ciência ID
6718-2ED6-30B6
ORCID iD
0000-0002-7724-0446
Google Scholar ID
GPBCJzwAAAAJ
Researcher Id
A-7414-2010
Scopus Author Id
22956209700

Email addresses

  • luisapinto@med.uminho.pt (Professional)
  • luisapinto@bnml.eu (Professional)

Telephones

Telephone
  • 253604929 (Professional)

Addresses

  • Instituto de Investigação em Ciências da Vida e Saúde (ICVS). Escola de Medicina - Universidade do Minho, Campus de Gualtar, 4710-057 , Braga, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2013/06
Concluded
 Post-doctoral degree in Neurosciences (Pós-doutoramento)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2008/11
Concluded
 PhD degree in Neurobiology (Doktor (PhD))
Ludwig-Maximilians-Universitat Munchen, Germany
"Molecular mechanisms regulating neurogenesis in the developing mouse cerebral cortex" (THESIS/DISSERTATION)
 summa cum laude - 0.5 (Excellent)
2004/06
Concluded
 University Degree in Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"--" (THESIS/DISSERTATION)
 16
2004/06
Concluded
 Diploma/Internship in Neurobiology (Especialização pós-licenciatura)
Karolinska Department of Cell and Molecular Biology, Sweden
 19
Affiliation

Science

Category
Host institution 		Employer
2021/05/03 - Current Auxiliary Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho, Portugal
2020/06/30 - 2021/04/30 Contracted Researcher (Research) B’acis – Associação Ciência, Inovação e Saúde, Portugal
Universidade do Minho, Portugal
2015/06/30 - 2020/06/29 Auxiliary Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2013/07/15 - 2015/06/29 Auxiliary Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2009/01/01 - 2013/06/15 Postdoc (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2009/11/01 - Current Invited Assistant Professor (University Teacher) Universidade do Minho Escola de Medicina, Portugal

Positions / Appointments

Category
Host institution 		Employer
2023/03/01 - Current Member of the Direction Board of ICVS Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023 - Current Member of the Course Commission for the Doctoral Program in Health Sciences Universidade do Minho, Portugal
2022 - Current Team Coordinator of the thematic line - Brain circuits and neuron-glia adaptations Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/09 - Current Coordinator of the Post-graduation Advanced Courses Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho, Portugal
2017/09/01 - Current Coordinator of Bio-entrepeneurship Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Others

Category
Host institution 		Employer
2012/01/26 - Current Partner of BNML - Behavioral & Molecular Lab, start-up of the University of Minho since January 2012 BNML - Behavioral & Molecular Lab LDA , Portugal
Projects

Grant

Designation Funders
2023/03/03 - Current Impact of hippocampal Adult-Born Neurons for Brain Circuitry and Behavior in the context of Depression
2021.09229.CBM
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia

Campus France
Ongoing
2020/12 - Current Neuronal circuits of reward and aversion: where do endogenous opioids stand?
PTDC/MED-NEU/4804/2020
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Ongoing
2020/09 - Current Encoding reward and aversion in the mammalian brain: the overlooked role of endogenous opioids
HR20-01000
Researcher
Obra Social La Caixa, Spain
 Obra Social La Caixa
Ongoing
2020/01/01 - Current SynChronize – Focused Ultrasound combined with Stem Cells Secretome and Pharmacotherapies: establishing a Multimodal path for Parkinson’s Disease repair
SynChronize
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Santa Casa da Misericórdia de Lisboa
Ongoing
2019/11 - Current Impact of adult astrogliogenesis in the brain
ID 11641
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Nature's Own Research Association
Ongoing
2023/03/01 - 2026/02/28 Hippocampal connectivity and behavioral performance in health and depression: where does adult astrogliogenesis stand?
2022.02201.PTDC
10.54499/2022.02201.PTDC
Principal investigator
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2021/06/30 Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia
721236
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Ongoing
2021 - 2021 Understanding the pathophysiology of depression by interrogating the role of adult astrogliogenesis in hippocampal connectivity
2020.02855.CEECIND
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Concluded
2018 - 2021 Impact of prenatal stress in the reward system: from depression to addiction and back
PTDC/MED-NEU/29071/2017
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Ongoing
2015/09 - 2020/08 Gliogenesis control of brain neuroplasticity, neurophysiology and cognitive function
427/14
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação Bial
Ongoing
2015/07 - 2020/05 EpiDep" - (Epi)genetic control of brain plasticity and function: a focus on depression
IF/01079/2014
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Ongoing
2015/09 - 2019/08 Gliogenesis control of brain neuroplasticity, neurophysiology and cognitive function
427/14
 Fundação Bial
2016 - 2019 Predicting the effects of antidepressants in the recovery, remission and relapse of depression: a novel multimodal approach
PTDC/DTP-PIC/6936/2014
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Ongoing
2016 - 2019 Personalized NOS - NORTE-01-0145-FEDER-000013
NORTE-01-0145-FEDER-00001
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 European Regional Development Fund
Ongoing
2012/08 - 2015/05 Translation of neuron-glia interactions in complex cognitive functions
61/10
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação Bial
Concluded
2014 - 2015 Integrative functional analysis of TET-mediated epigenetic regulation of neurogenesis
EpiGeneSys
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 FP7 European Community-funded Network of Excellence
Concluded
2012 - 2015 The interplay between astrocytes and neurons in the progression of stress-induced pathologies
PTDC/SAU-NSC/118194/2010
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Concluded
2012 - 2014 Development of an automated system to expose rodents to chronic stress and modulate neuropshychiatric disorders
Project Nº 2012/23712
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 National Strategic Reference Framework (QREN)
Concluded
2010 - 2013 Multimodal analysis of the neurobiology of depression
PTDC/SAU-NEU/105180/2008
Research Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Concluded
2010 - 2012 Neudesina - function study of a new neurotrophic factor
PTDC/SAU-OSM/104475/2008
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e Tecnologia (FCT)
Concluded

Contract

Designation Funders
2021/12/06 - 2027/12/05 Contract of Assistant Researcher with tenure
CEECINST/00077/2018/CP1640/CT0003
10.54499/CEECINST/00077/2018/CP1640/CT0003
Principal investigator
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 ICVS/3B¿s - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis e Biomiméticos
LA/P/0050/2020
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 ICVS/3B¿s - Associate Laboratory, Life and Health Sciences Research Institute / Biomaterials, Biodegradables and Biomimetics Research Group
UID/Multi/50026/2019
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015 - 2017 Bn'ML project for the development and validation of an automated equipment to induce depressive-like behavior in rats
-
BnML Behavioral and Molecular Lab Lda, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
BnML Behavioral and Molecular Lab Lda
Concluded
2013 - 2016 Study of the antidepressant properties of Pirlindol in an animal model of Chronic Mild Stress
Tecnimede2013
Supervisor
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Grupo Tecnimede
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 26 - 2011-2012
PEst-C/SAU/LA0026/2011
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2012 Evaluation of the behavioural effects of BI and MTEP compounds in an animal model of depression
BI2011
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Boehringer Ingelheim Pharma GbmH
Concluded

Other

Designation Funders
2023/03/01 - 2027/02/28 Health from Portugal (HfPT)”, Portuguese Government Recovery and Resilience Plan (RRP)
HfPT
Co-Principal Investigator (Co-PI)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Ongoing
Outputs

Publications

Book chapter
  1. Mateus-Pinheiro, António; Pinto, Luísa; Sousa, Nuno. "Sistemas de Memória". In Neurociências, 307-324. Lidel, 2017.
    Published
Conference abstract
  1. Patricio, P.; Mateus-Pinheiro, A.; Machado-Santos, A.; Alves, N.; Morais, M.; Bessa, J.; Sousa, N.; Pinto, L.. "S.15.06 Cell cycle regulation of the progenitor cells from the adult hippocampal dentate gyrus in depression and by antidepressants". 2015.
    Published • 10.1016/s0924-977x(15)30080-8
  2. S. Henriques; L. Caetano; P. Patrício; Soares-Cunha, Carina; A. Mateus-Pinheiro; N.D. Alves; Baptista, FI; et al. "Anxiety caused by prenatal immunomodulation is paralleled by an atrophy of microglial processes in the pre-frontal cortex of female rats.". Paper presented in XIVth meeting of the Portuguese Society for Neurosciences, Póvoa do Varzim, 2015.
  3. Pinto, Luisa. "Radial glia, astrocytes and stem cells-common mechanisms of neurogenesis?". 2007.
    Published
Conference paper
  1. Lapo Pais, Mariana; Ribeiro, Inês; Martins, João; Pinto, Luisa; Castelo-Branco, Miguel; Gonçalves, Joana. "SEX DIFFERENCES IN THE DENDRITIC MORPHOLOGY OF TEMPORAL CORTICAL NEURONS IN ADULT MICE". Paper presented in 11th IBRO World Congress, Granada, 2023.
    Published
Conference poster
  1. Araújo, Bruna; Joana Catarina Martins Macedo; Silveira-Rosa, Tiago; Patrícia Carvalho Patrício; Loureiro-Campos, Eduardo; Caridade-Silva, Rita; Teixeira, Fábio Gabriel; et al. "Hilus, a new cytogenic hippocampal niche modulated by stress exposure and treatment with antidepressants". Paper presented in 11th IBRO - World Congress of Neuroscience 2023, 2023.
  2. Correia, Raquel; Domingues, Ana Verónica; Coimbra, Bárbara; Wezik, Marcelina Olga; Vieitas-Gaspar, Natacha; Sousa, Nuno; Pinto, Luisa; Rodrigues, Ana João; Soares-Cunha, Carina. "Nucleus accumbens D2 medium spiny neuron projections to the ventral pallidum promote anxiety-like behaviour". Paper presented in ECNP Workshop for Early Career Scientists in Europe, 2023.
  3. Abreu, Daniela Sofia; Viana, João Filipe; Guerra-Gomes, Sónia; Soledade, Francisca; Machado, João Luís; Nascimento, DSM; Pinto, Luisa; Teixeira-Castro, Andreia; Oliveira, João Filipe. "The involvement of astrocyte calcium-dependent signaling in behavior". Paper presented in FENS Forum - Federation of European Neuroscience Societies, 2022.
  4. Viana, João Filipe; Guerra-Gomes, Sónia; Soledade, Francisca; Machado, João Luís; Marques Nascimento, Diana Sofia; Caetano, Inês; Sousa, Nuno; Pinto, Luisa; Oliveira, João Filipe. "The role of astrocytic calcium-dependent signaling in cognitive function". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  5. Rodrigues-Neves, A; Gaspar, Rita; Patrício, P; Lima, Susana; Silveira-Rosa, T; Martins-Macedo, J; Araújo, B.; et al. "Microglia, a key element in schizophrenia pathophysiology: insights from an animal model". Paper presented in EMBO Workshop Microglia 2020 - EMBL Heidelberg, Germany, 2020.
  6. Gaspar, Rita; Rodrigues-Neves Ana C; Patrício, Patricia; Lima Susana; Silveira-Rosa, Tiago; Macedo Joana; Araújo Bruna; et al. "Microglia morphologic characterization in brain regions associated with hyper- and hipofunctional neuronal pathways in a rodent model of schizophrenia". Paper presented in 3rd Symposium on Physiology and pathology of neuroglia, 2020.
  7. Silveira-Rosa, T; Patrício, P; Mateus-Pinheiro, A; Araújo, B.; Martins-Macedo, J; Loureiro-Campos, E; Lima, Susana; et al. "Circuitry and connectivity of hippocampal neurons in the context of depression and antidepressant treatment". Paper presented in XIII NeRD retreat, Guimarães, Portugal, 2019.
  8. Lima, Susana; Patrício, P; Silveira-Rosa, T; Araújo, B.; Martins-Macedo, J; Pinto, Luisa. "The impact of reproductive experience in females on the susceptibility and treatment of depressive-like behavior with allopregnanolone". Paper presented in XIII NeRD retreat 2019, Guimarães, Portugal, 2019.
  9. Araújo, Bruna; Silveira-Rosa, Tiago; Joana Catarina Martins Macedo; Loureiro-Campos, Eduardo; Patrício, Patrícia; Sousa, Nuno; Mateus-Pinheiro, António; Pinto, Luisa. "Revisiting Neurogenesis in the Adult Mammalian Brain Unveiling Hilar Neurogenesis". Paper presented in VI AEICBAS Biomedical Congress, 2019.
  10. Gaspar, Rita; Mendes-Duarte, Joana; Patrício, Patrícia; Soares-Cunha, Carina; Mateus-Pinheiro, A.; Alves, Nuno Dinis; Santos, Ana Rita; et al. "Brain region duality in the regulation of microglia morphology by adenosine A2A receptors: implications for anxiety and cognition". Paper presented in XIII European Meeting on Glial Cells in Health and Disease, 2017.
  11. Gaspar, Rita; Mendes-Duarte, Joana; Patrício, Patricia; Soares-Cunha, Carina; Mateus-Pinheiro, A.; Alves, Nuno Dinis; Santos, Ana Rita; et al. "Modulation of microglia morphology by adenosine A2A receptors: impact for anxiety and cognition". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, 2017.
  12. Gaspar, Rita; Henriques, Carla Simões; Mendes-Duarte, Joana; Pinheiro, Helena; Soares-Cunha, Carina; Mateus-Pinheiro, A.; Alves, Nuno Dinis; et al. "Chronic blockade of adenosine A2AReceptors: Gender-specific reprogramming of microglia morphology in the PFC". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, 2017.
  13. Santos, A.R.; Mateus-Pinheiro, A.; Alves, N.D.; Patrício, P.; Morais, M.; Oliveira, J.F.; Sousa, N.; Pinto, L.. "P.4.012 Glial plasticity as a key mechanism underlying the pathophysiology of depression". 2016.
    10.1016/s0924-977x(16)70102-7
  14. Soares-Cunha, C; Coimbra, Bárbara; David-Pereira, A; Borges, S; Pinto, Luisa; Costa, P; Sousa, Nuno; Rodrigues, AJ. "D2-expressing neurons in the nucleus accumbens modulates motivation". Paper presented in FENS SfN Summer School. Bertinoro, Italy, 29 May- 4 June 2016., 2016.
  15. Soares-Cunha, C; Coimbra, Bárbara; David-Pereira, A; Borges, S; Pinto, Luisa; Costa, P; Sousa, Nuno; Rodrigues, AJ. "D2-expressing neurons in the nucleus accumbens modulate motivation". Paper presented in 10th FENS Forum of Neuroscience. Copenhagen, Denmark, 2-6 July 2016., 2016.
  16. Soares-Cunha, C; Coimbra, Bárbara; David-Pereira, A; Borges, S; Pinto, Luisa; Costa, P; Sousa, Nuno; Rodrigues, AJ. "Activation of D1- and D2-expressing neurons in the nucleus accumbens enhances motivation". Paper presented in Society for Neuroscience (SfN). San Diego, USA, 12-16 November 2016., 2016.
  17. Machado-Santos, A.R.; Mateus-Pinheiro, A.; Alves, N.D.; Patricio, P.; Morais, M.; Oliveira, J.F.; Sousa, N.; Pinto, L.. "P.1.d.005 Glial plasticity as a key mechanism underlying the pathophysiology of depression". 2015.
    10.1016/s0924-977x(15)30214-5
  18. Alves, N.; Machado-Santos, A.; Mateus-Pinheiro, A.; Patrício, P.; Correia, J.; Morais, M.; Bessa, J.; Sousa, N.; Pinto, L.. "P.4.c.004 Adult neuroplasticity as a pathological trigger of recurrence in depression". 2015.
    10.1016/s0924-977x(15)30789-6
  19. Soares-Cunha, C; Coimbra, Bárbara; David-Pereira, A.; Borges, S; Pinto, Luisa; Costa, P; Deisseroth, K; Sousa, Nuno; Rodrigues, AJ. "Activation of D2-expressing neurons in the nucleus accumbens enhances motivation". Paper presented in Neuroscience (SfN). Chicago, USA, 17-21 October, 2015., 2015.
  20. Soares-Cunha, C.; Coimbra, Bárbara; David-Pereira, A; Borges, S; Pinto, Luisa; Costa, P; Deisseroth, K; Sousa, Nuno; Rodrigues, AJ. "Stimulation of dopamine D2-expressing neurons in the nucleus accumbens facilitates motivation". Paper presented in XIV Meeting of the Portuguese Society for Neuroscience (SPN). Póvoa de Varzim, Portugal, 4-5 June 2015, 2015.
    10.1109/iembs.2009.5333768
  21. Soares-Cunha, C; Coimbra, Bárbara; David-Pereira, A.; Borges, S; Pinto, Luisa; Costa, P; Deisseroth, K; Sousa, Nuno; Rodrigues, AJ. "dopamine D2 receptor activation in the nucleus accumbens regulates motivation". Paper presented in ECNP Workshop for Junior Scientists in Europe. Nice, France, 12-15 March 2015., 2015.
  22. Morais, M.; Pinheiro, A.; Patricio, P.; Alves, D.; Pinto, L.; Sousa, N.; Bessa, J.. "P.3.026 The impact of antipsychotic drugs in depression: a role for adult neurogenesis?". 2014.
    10.1016/s0924-977x(14)70086-0
  23. Morais, M.; Pinheiro, A.; Patricio, P.; Alves, D.; Pinto, L.; Sousa, N.; Bessa, J.. "P.3.026 The impact of antipsychotic drugs in depression: a role for adult neurogenesis?". 2014.
    10.1016/s0924-977x(14)70086-0
  24. Stahl, R.; Walcher, T.; Pinto, L.; Blum, R.; Goetz, M.. "Identification and function of a novel nuclear protein in neurogenesis". 2010.
    10.1016/j.ijdevneu.2010.07.117
Edited book
  1. Pinto, Luisa; Oliveira, João Filipe; Sousa, Nuno; Catarina A Gomes; Sandra Henriques Vaz. Glial Plasticity in Depression. Frontiers Media SA. 2016.
    10.3389/978-2-88919-999-0
Journal article
  1. Zeynep Seda Albayrak; Andreia de Fátima da Silva Vaz; Joeri Bordes; Selen Ünlü; Milou S.C. Sep; Christiaan H. Vinkers; Luisa Pinto; Hale Yapici Eser. "Translational models of stress and resilience: An applied neuroscience methodology review". Neuroscience Applied (2024): https://doi.org/10.1016/j.nsa.2024.104064.
    10.1016/j.nsa.2024.104064
  2. Rodrigues, R. S.; Moreira, J. B.; Mateus, J. M.; Barateiro, A.; Paulo, S. L.; Vaz, S. H.; Lourenço, D. M.; et al. "Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress". Translational Psychiatry 14 1 (2024): http://dx.doi.org/10.1038/s41398-024-02877-0.
    10.1038/s41398-024-02877-0
  3. Martins-Macedo, Joana; Araújo, Bruna; Anjo, Sandra I.; Silveira-Rosa, Tiago; Patrício, Patrícia; Alves, Nuno Dinis; Silva, Joana M.; et al. "Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation". Molecular Psychiatry (2024): http://dx.doi.org/10.1038/s41380-024-02490-z.
    10.1038/s41380-024-02490-z
  4. Deseyve, Catarina; Domingues, Ana Verónica; Carvalho, Tawan T. A.; Armada, Gisela; Correia, Raquel; Vieitas-Gaspar, Natacha; Wezik, Marcelina; et al. "Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning". Journal of Neurochemistry 168 3 (2024): 312-327. http://dx.doi.org/10.1111/jnc.16063.
    10.1111/jnc.16063
  5. Klados, Manousos; Pinto, Luisa. "Navigating the frontiers of neuroscience". Brain Organoid and Systems Neuroscience Journal 1 (2023): 1-2. http://dx.doi.org/10.1016/j.bosn.2023.10.001.
    10.1016/j.bosn.2023.10.001
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  65. Lima, A.; Sardinha, V.M.; Oliveira, A.F.; Reis, M.; Mota, C.; Silva, M.A.; Marques, F.; et al. "Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats". Molecular Psychiatry 19 7 (2014): 834-841. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891898422&partnerID=MN8TOARS.
    10.1038/mp.2013.182
  66. Mateus-Pinheiro, A.; Patrício, P.; Alves, N.D.; Machado-Santos, A.R.; Morais, M.; Bessa, J.M.; Sousa, N.; Pinto, L.. "The Sweet Drive Test: Refining phenotypic characterization of anhedonic behavior in rodents". Frontiers in Behavioral Neuroscience 8 MAR (2014): 74. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896934696&partnerID=MN8TOARS.
    10.3389/fnbeh.2014.00074
  67. Morais, M.; Santos, P.A.R.; Mateus-Pinheiro, A.; Patrício, P.; Pinto, L.; Sousa, N.; Pedroso, P.; et al. "The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition". Journal of Psychopharmacology 28 12 (2014): 1178-1183. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911109619&partnerID=MN8TOARS.
    10.1177/0269881114553646
  68. Mateus-Pinheiro, A.; Pinto, L.; Bessa, J.M.; Morais, M.; Alves, N.D.; Monteiro, S.; Patrício, P.; Almeida, O.F.; Sousa, N.. "Sustained remission from depressive-like behavior depends on hippocampal neurogenesis.". Translational psychiatry 3 e210 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84879414589&partnerID=MN8TOARS.
    10.1038/tp.2012.141
  69. Mateus-Pinheiro, A.; Patrício, P.; Bessa, J.M.; Sousa, N.; Pinto, L.. "Cell genesis and dendritic plasticity: A neuroplastic pas de deux in the onset and remission from depression". Molecular Psychiatry 18 7 (2013): 748-750. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879409713&partnerID=MN8TOARS.
    10.1038/mp.2013.56
  70. Borges, S.; Coimbra, B.; Soares-Cunha, C.; Ventura-Silva, A.P.; Pinto, L.; Carvalho, M.M.; Pêgo, J.-M.; Rodrigues, A.J.; Sousa, N.. "Glucocorticoid programing of the mesopontine cholinergic system". Frontiers in Endocrinology 4 DEC (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84892156422&partnerID=MN8TOARS.
    10.3389/fendo.2013.00190
  71. Ribeiro-Samy, S.; Silva, N.A.; Correlo, V.M.; Fraga, J.S.; Pinto, L.; Teixeira-Castro, A.; Leite-Almeida, H.; et al. "Development and characterization of a PHB-HV-based 3D scaffold for a tissue engineering and cell-therapy combinatorial approach for spinal cord injury regeneration". Macromolecular Bioscience 13 11 (2013): 1576-1592. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887825122&partnerID=MN8TOARS.
    10.1002/mabi.201300178
  72. Patrício, P.; Mateus-Pinheiro, A.; Sousa, N.; Pinto, L.. "Re-cycling paradigms: Cell cycle regulation in adult hippocampal neurogenesis and implications for depression". Molecular Neurobiology 48 1 (2013): 84-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880924582&partnerID=MN8TOARS.
    10.1007/s12035-013-8422-x
  73. Bessa, J.M.; Morais, M.; Marques, F.; Pinto, L.; Palha, J.A.; Almeida, O.F.X.; Sousa, N.. "Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens". Translational Psychiatry 3 e266 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84879969155&partnerID=MN8TOARS.
    10.1038/tp.2013.39
  74. Pinto, L.; Mateus-Pinheiro, A.; Morais, M.; Bessa, J.M.; Sousa, N.. "Immuno-golgi as a tool for analyzing neuronal 3D-dendritic structure in phenotypically characterized neurons". PLoS ONE 7 3 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84858052488&partnerID=MN8TOARS.
    10.1371/journal.pone.0033114
  75. Mateus-Pinheiro, A.; Pinto, L.; Sousa, N.. "Epigenetic (de)regulation of adult hippocampal neurogenesis: Implications for depression". Clinical Epigenetics 3 3 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880921625&partnerID=MN8TOARS.
    10.1186/1868-7083-3-5
  76. Ninkovic, J.; Pinto, L.; Petricca, S.; Lepier, A.; Sun, J.; Rieger, M.A.; Schroeder, T.; et al. "The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin aA". Neuron 68 4 (2010): 682-694. http://www.scopus.com/inward/record.url?eid=2-s2.0-78449311026&partnerID=MN8TOARS.
    10.1016/j.neuron.2010.09.030
  77. Pinto, L.; Drechsel, D.; Schmid, M.-T.; Ninkovic, J.; Irmler, M.; Brill, M.S.; Restani, L.; et al. "Erratum: AP2¿ regulates basal progenitor fate in a region-and layer-specific manner in the developing cortex (Nature Neuroscience (2009) 12 (1229-1237))". Nature Neuroscience 13 5 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77951691098&partnerID=MN8TOARS.
    10.1038/nn0510-649c
  78. Pinto, L.; Drechsel, D.; Schmid, M.-T.; Ninkovic, J.; Irmler, M.; Brill, M.S.; Restani, L.; et al. "AP2¿ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex". Nature Neuroscience 12 10 (2009): 1229-1237. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349554036&partnerID=MN8TOARS.
    10.1038/nn.2399
  79. Pinto, Luisa; Gotz, Magdalena. "Glial Cells as the Source of Neurons and Glia in the Developing and Adult CNS". Journal of Medical Sciences 1 3 (2008): 114-128. http://dx.doi.org/10.2174/1996327000801030114.
    10.2174/1996327000801030114
  80. Bonilla, S.; Hall, A.C.; Pinto, L.; Attardo, A.; Götz, M.; Huttner, W.B.; Arenas, E.. "Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors". GLIA 56 8 (2008): 809-820. http://www.scopus.com/inward/record.url?eid=2-s2.0-46749154758&partnerID=MN8TOARS.
    10.1002/glia.20654
  81. Pinto, L.; Mader, M.T.; Irmler, M.; Gentilini, M.; Santoni, F.; Drechsel, D.; Blum, R.; et al. "Prospective isolation of functionally distinct radial glial subtypes-Lineage and transcriptome analysis". Molecular and Cellular Neuroscience 38 1 (2008): 15-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-43049119575&partnerID=MN8TOARS.
    10.1016/j.mcn.2008.01.012
  82. Pinto, L.; Götz, M.. "Radial glial cell heterogeneity-The source of diverse progeny in the CNS". Progress in Neurobiology 83 1 (2007): 2-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547812737&partnerID=MN8TOARS.
    10.1016/j.pneurobio.2007.02.010
  83. Nikoletopoulou, V.; Plachta, N.; Allen, N.D.; Pinto, L.; Götz, M.; Barde, Y.-A.. "Neurotrophin Receptor-Mediated Death of Misspecified Neurons Generated from Embryonic Stem Cells Lacking Pax6". Cell Stem Cell 1 5 (2007): 529-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-35848955674&partnerID=MN8TOARS.
    10.1016/j.stem.2007.08.011
  84. Castelo-Branco, G.; Sousa, K.M.; Bryja, V.; Pinto, L.; Wagner, J.; Arenas, E.. "Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion". Molecular and Cellular Neuroscience 31 2 (2006): 251-262. http://www.scopus.com/inward/record.url?eid=2-s2.0-32244442041&partnerID=MN8TOARS.
    10.1016/j.mcn.2005.09.014
Preprint
  1. Luísa Pinto; Joana Macedo; Bruna Araújo; Sandra Anjo; Tiago Silveira-Rosa; Patrícia Patrício; Fábio Teixeira; et al. "Glial-Restricted Precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation". 2023. https://doi.org/10.21203/rs.3.rs-2747462/v1.
    10.21203/rs.3.rs-2747462/v1
Thesis / Dissertation
  1. Pinto, Luisa. "Molecular mechanisms regulating neurogenesis in the developing mouse cerebral cortex". PhD, Ludwig Maximilians Universität München Department Biologie I, 2008. https://pdfs.semanticscholar.org/2363/fd4071839f714d624f7c9ef8a5179e3a0ca0.pdf.

Intellectual property

Patent
  1. Pinto, Luisa; antónio salgado; ana marote; bárbara pinheiro. 2020. "Compositions for therapy or treatment of Parkinson´s disease, methods and uses thereof".
    Pending
  2. Pinto, Luisa; antónio salgado; nuno silva; rita silva; eduardo gomes; sofia serra; jorge ribeiro; susana monteiro; andreia pinho. 2020. "Compositions for treatment of spinal cord injury, methods and uses thereof".
    Pending
  3. Pinto, Luisa; Sousa, Nuno; Bessa, João M.; Mateus-Pinheiro, António; Morais, Mónica. 2012. "Immuno-Golgi as a tool for analyzing neuronal 3D-dendritic structure in phenotypically charaterized neurons". Portugal.
    Granted/Issued

Other

Other output
  1. Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior. 2020. Carina Soares-Cunha; Raquel Correia; Ana Verónica Domingues; Bárbara Coimbra; Nivaldo AP de Vasconcelos; Luísa Pinto; Nuno Sousa; Ana João Rodrigues. https://doi.org/10.1101/2020.11.27.401042.
    10.1101/2020.11.27.401042
Spin-off company
  1. 2012. BNML – Behavioral & Molecular Lab. Neurosciences. https://www.bnml.eu/.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/05/24 Time-dependent functional correlates of adult hippocampal cytogenesis: Relevance to stress-induced Depression NeuroFrance 2023
NeuroFrance (Lyon, France)
2023/05/03 Impact of adult hippocampal cytogenesis modulation on brain physiology and behavior FENS Regional Meeting, Faro, Portugal,
FENS (Faro)
2022/07/07 Adult astrogliogenesis as a key mechanism underlying the pathophysiology of stress-induced depression Satellite event of the FENS Forum 2022
FENS (Paris, France)
2022/03/10 Time-dependent functional correlates of adult hippocampal cytogenesis: Relevance to Depression 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
Portuguese Society for Stem Cells and Cell Therapies (Braga)
2021/07/19 Time-dependent functional correlates of adult hippocampal cytogenesis: Relevance to Depression”. Seminaries in Mental Health organized by the Portuguese Society for Neuroscience (SPN)
Portuguese Society for Neuroscience (Portugal)
2019/08/31 Glial plasticity as a key mechanism underlying the pathophysiology of depression EBPS Biennial Meeting
European Behavioural Pharmacology Society (Braga, Portugal)
2019/06/25 Glial plasticity as a key mechanism underlying the pathophysiology of depression 7th Mediterranean Neuroscience Society Conference
Mediterranean Neuroscience Society (Marrakech, Marocco)
2019/06/13 Time-dependent functional correlates of adult hippocampal cytogenesis: Relevance to Depression Eurogenesis 4th Meeting
Eurogenesis (Bordeaux, France)
2019/03/29 Genetic and Epigenetic factors that modulate stress-induced Neuro- and Glio-plasticity in an animal model of Depression Symposium on Animal Models of Affective Disorders
(Bochum, Germany)
2018/10 Impact of adult hippocampal cytogenesis modulation on behavior and brain physiology: relevance for Depression Seminários FMUP
(Porto, Portugal)
2018/05 Beyond new neurons in the adult brain: on the role of adult glial plasticity in the depressed brain III Symposium of the Portuguese Glial Network
(Porto, Portugal)
2018/04 Impact of adult hippocampal cytogenesis modulation on cognitive behavior and brain physiology 2018 International Conference on Learning and Memory
(California, United States)
2017/11 Behavioral and Molecular Solutions for pre-clinical tests of compounds 3rd PhD Meeting of the the Mind-Brain College of the University of Lisbon
(Lisbon, Portugal)
2017/06 Genetic and epigenetic factors that modulate neuro- and glio-plasticity: Relevance to depression Mediterranean Neuroscience Conference
(St. Julian's, Malta)
2016/10 Genetic and epigenetic factors that modulate neuro- and glio-plasticity in depression 29th ECNP Congress
(Vienna, Austria)
2016/07 Genetic and Epigenetic Factors that Modulate Stress–Induced Neuro- and Glia-Plasticity: Relevance for Depression 10th FENS Forum of Neuroscience
(Copenhagen, Denmark)
2015/12 Genetic and Epigenetic Factors that Modulate Stress–Induced Neuro- and Glia-Plasticity: Relevance for Depression NeuroConferences @ ICVS
(Braga, Portugal)
2015/06 Genetic and epigenetic factors that modulate neuro and glio-plasticity in depression CINP Thematic Meeting on Stress, inflammation and depression: focus on novel antidepressant targets
(Dublin, Ireland)
2015/05 Epigenetic factors that modulate neuro and glio-plasticity in depression 1st Joint Neuromeeting IBI-ICVS
(Vigo, Spain)
2015/05 Genetic and Epigenetic Factors that Modulate Stress–Induced Neuro- and Glia-Plasticity: Relevance for Depression Joint Neuroscience Symposium at Thomas Jefferson University
(Philadelphia, United States)
2015/04 Seeking and testing new therapeutical approaches in Neurosciences Health Clusters Portugal Meeting on Translational and clinical research: from bench to bedside
(Coimbra, Portugal)
2014/06 Cell genesis and dendritic plasticity: A neuroplastic pas de deux in the onset and remission from depression 29th CINP World Congress
(Vancouver, Canada)
2009/06 AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex Meeting of the Portuguese Society of Neurosciences
Portuguese Society of Neurosciences (Braga, Portugal)
2008/05 AP2gamma regulates basal progenitor fate and upper layer neuron specification in the mouse cerebral cortex Cortical Development Meeting
(Crete, Greece)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024 - Current Does adult hippocampal gliogenesis modulate non-motor symptoms of PD? Understanding the role of newly-born glial cells in PD progression
Co-supervisor
 Biomedicine (PhD)
2023 - Current Decoding the neuron-astrocyte dialogue that supports cognitive processing
Co-supervisor
 Health Sciences (PhD)
Universidade do Minho, Portugal
2023 - Current Modulation of adult hippocampal neurogenesis by antidepressants may aid the prevention of Parkinson’s Disease
Co-supervisor
 Biomedicine (PhD)
2023 - Current The involvement of astrocytes in depression: a role for region specific gliotransmission
Co-supervisor
 Health Sciences (PhD)
Universidade do Minho, Portugal
2023 - Current Testing of novel virus tools to ablate astrogliogenesis in the brain of rodents
Supervisor
 Biotechnology (Master)
Universidade do Minho, Portugal
2023 - Current Impact of astrogliogenesis on hippocampal connectivity and behavior
Supervisor
 Bioengineering (Master)
2023 - Current Impact of modulation of hippocampal adult-born neurons in the context of depression and antidepressant treatment
Supervisor
 Health Sciences (Master)
Universidade do Minho, Portugal
2022 - Current Tau protein as a regulator of the hippocampal neurogenic niche
Co-supervisor
 Health Sciences (Master)
2022 - Current Understanding the role of astrogliogenesis on brain physiology and behavior
Supervisor
 Biomedical Research (Master)
Universidade de Coimbra, Portugal
2021/02/01 - Current Impact of hippocampal adult-born neurons for brain circuitry and behavior in depression
Supervisor of Inês Ribeiro
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021 - Current The rostral ventromedial medulla as a key target of the maladaptive response to chronic inflammatory pain
Co-supervisor of Diana Rodrigues
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020 - Current Modeling and assessing the neurobiological mechanisms of depression: perspectives from patient-derived iPSC models
Supervisor of Andreia Vaz
 Applied Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/11 - Current Beyond new neurons in the adult brain: on the role of adult astrogliogenesis in the healthy and depressed brain
Supervisor of Eduardo Campos
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09 - Current Unveiling the effects of MSCs Secretome in Parkinson’s Disease: Impact of Neurogenesis Mediated Repair
Co-supervisor of Bárbara Pinheiro
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09 - Current Circuitry and connectivity of Hippocampal Neurons in the context of depression and antidepressant treatment
Supervisor of Tiago Silveira Rosa
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09 - 2021 A Poly-Pharmacological Therapy to Repair the Injured Spinal Cord
Co-supervisor of Rui Lima
 Applied Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09 - 2021 Modulation of neuronal proteostasis by serotonin: impact on neurodegeneration
Co-supervisor of Joana Sousa
 Applied Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/09 - 2020/09/07 Implementation of a chronic social stress rat model and the effects of allopregnanolone to reverse depressive and anxiety-like signs in nulliparous and primiparous females.
Supervisor of Susana Lima
 Health Sciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/10 - 2020/07/30 Gliogenesis as an important mechanism underlying the pathophysiology of depression
Supervisor of Ana Rita Santos
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/07 - 2020/07/29 Unveiling the potential of iPSCs-derived mesenchymal stem cells for the development of cell-free therapies for Parkinson’s disease
Co-supervisor of Ana Marote
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/09/03 - 2020/07/27 Transplanting Glial Restricted Precursors into a model of cytogenesis ablation: Uncovering the interplay between neuro- and gliogenesis
Supervisor of Joana Macedo
 Health Sciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/07 - 2020/06/29 Modulation of Mesenchymal Stem Cells Secretome through Peptide Grafted 3D Culture Environments: A Focus on Spinal Cord Injury Repair
Co-supervisor of Rita Catarina Assunção Ribeiro Silva
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/10 - 2020/06/19 Role of Tet3 and DNA hydroxymethylation in brain function
Supervisor of Claudia Filipa Cunha Antunes
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/01 - 2020/01/21 The impact of neuron-astrocyte networks on cognitive function in depression
Co-supervisor of Sónia Isabel Nunes Guerra Gomes
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/07 - 2020 Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia - under the Marie Curie Innovative Training Network
Supervisor of Raphael Sirtoli
 Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/01 - 2019/12 Hippocampal adult-born neurons in depression and after antidepressant treatment: implications for circuitry and behavior
Supervisor of Patrícia Carvalho Patrício
 Post-doc in Health Sciences (Other)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09/01 - 2019/10/14 Hilar hippocampal cytogenesis: A new source of neural plasticity in the adult mammalian brain?
Supervisor of Bruna Araújo
 Health Sciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/05 - 2018/07 Analysis of cell proliferation and differentiation in an in vitro model to study the effect of stress hormones and antidepressants in the adult hippocampal neurogenic niche
Supervisor of Alexandra Filipa Basílio Silva
 Applied Biochemistry (Degree)
Universidade do Minho, Portugal
2017/05 - 2018/01 Role of the TET3 enzyme in neuronal morphology and synaptic structure of the hippocampus
Supervisor of Fábio Alexandre Lopes Ferreira
Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/07 - 2018/01 Suppression of adult hippocampal cytogenesis in the female brain induces hypercorticosteronemia and anxiety-like behavior
Supervisor of António Maria Testolho Mateus Pinheiro
Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/05 - 2017/07 Relevance of adult hippocampal cytogenesis to mice behavior and the function of female hormones
Supervisor of Joana Catarina Martins Macedo
 Applied Biochemistry (Degree)
Universidade do Minho, Portugal
2017/05 - 2017/07 Glial plasticity as a key mechanism in an animal model of recurrent depression
Supervisor of Bruna Alexandra Vale Araújo
 Applied Biochemistry (Degree)
Universidade do Minho, Portugal
2017/05 - 2017/07 Function of the transcription factor AP2gamma in the modulation of post-natal glutamatergic neurogenesis
Supervisor of Ana Beatriz Pereira de Sousa
 Applied Biochemistry (Degree)
Universidade do Minho, Portugal
2017/01 - 2017/07 Cytogenic phenomena in the hippocampus in the context of glioblastoma
Supervisor of Daniela Veiga
 Biomedical Sciences (Degree)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2013/01 - 2017/07 Adult neuroplasticity as a pathological trigger to recurrence in depression
Supervisor of Nuno Dinis Alves
 PhD of the Inter-University Doctoral Programme in Ageing and Chronic Diseases (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/09 - 2017/03 Validation of an automated equipment for depression induction in a rodent model
Supervisor of Cátia Alves
 Neurosciences (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015/10 - 2016/10 The role of AP2gamma in the modulation of adult neurogenesis in depression
Supervisor of Eduardo Campos
 Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/05 - 2016/07 Impact of reduced neurogenesis in depressive-like behavior
Supervisor of Inês Marques Pinheiro
 Applied Biochemistry (Degree)
Universidade do Minho, Portugal
2011/10 - 2016/07 Epigenetic orchestration of the adult brain neuroplasticity in health and disease
Supervisor of António Maria Restolho Mateus Pinheiro
 Neurosciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/06 - 2016/05 Molecular signaling and cell cycle regulation by depression and antidepressant drugs
Supervisor of Patrícia Carvalho Patrício
 Neurosciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/08 - 2015/01 Epigenetic Mechanisms of Depression: Role of TET enzymes and DNA methylation/hydroxymethylation on healthy and depressed brains
Supervisor of Joana Marinho
 Medicine (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2013/10 - 2014/12 The impact of astrocytic neuroprotective function in depression
Co-supervisor of Joana Correia
 Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/06 - 2013/10 Identifying the mechanistic role of TAU on adult neurogenesis modifications induced by chronic stress and environmental enrichment
Co-supervisor of Rita Trindade
 Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/06 - 2013/07 Impact of astrocytes and gliogenesis on the pathophysiology of Depression
Supervisor of Ana Rita Santos
 Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2010/07 - 2011/07 Impact of neurogenic modulatory events on the neurobiology of depression
Supervisor of António Maria Restolho Mateus Pinheiro
 Neurosciences (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2010 - 2011 In Vivo Studies on the Effects of Umbilical Cord Stem Cells in the Central Nervous System
Co-supervisor of Fábio Teixeira
 Oncology (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2010/05 - 2010/07 Effects of the secretome of the human umbilical cord mesenchymal Stem Cells in the proliferation and differentiation of neuronal stem cells
Co-supervisor of Ana Raquel Marques de Sousa
 Applied Biochemistry (Degree)
Universidade do Minho, Portugal
2008/03 - 2008/07 Analysis of genes that were found to be differentially expressed in a microarray screen comparing the neural stem cells in the cortex and ganglionic eminences of the mouse developing forebrain
Co-supervisor of Marion Betizeau
 Neurobiology (Degree)
Helmholtz Zentrum München Deutsches Forschungszentrum für Umwelt und Gesundheit, Germany
2006/07 - 2007/03 Fate determinants for neurogenesis in the mouse developing cortex
Co-supervisor of Daniela Drechsel
 Neurobiology (Master)
Helmholtz Zentrum München Deutsches Forschungszentrum für Umwelt und Gesundheit, Germany

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/10/07 - 2023/10/10 Co-organizer/Member of the Scientific Programme Committee for the 36th European College of Neuropsychopharmacology (ECNP) Congress, Barcelona, Spain, 07-10 October 2023. (2023 - 2023)
Congress (Member of the Scientific Committee)
 European College of Neuropsychopharmacology, Netherlands
2022/03/07 - 2022/03/25 Co-organizer of the advanced course "Being a bio-entrepreneur" (8th Edition), Life and Health Sciences Research Institute (ICVS), Braga, Portugal. (2022 - 2022)
Other (Member of the Organising Committee)
 Universidade do Minho, Portugal
2021/03/02 - 2021/03/19 Member of the organising committee of the advanced course " Being a bio-entrepeneur" (2021/03/2 - 2021/03/19) (2021 - 2021)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020/02/10 - 2020/02/28 Member of the organising committee of the advanced course " Being a bio-entrepeneur" (2020/02/10 - 2020/02/28) (2020/02/10 - 2020/02/28)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09/28 - 2019/08/31 Co-organizer of the EBPS Biennial Meeting (2019/08/28 - 2019/08/31)
Congress (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/06/23 - 2019/06/27 Organizer of the Symposium “Neuroinflammation and glial plasticity in anxiety and depression: Underlying mechanisms and novel therapeutic targets” at the 7th Mediterranean Neuroscience Society Conference (2019/06/23 - 2019/06/27)
Symposium
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/03/04 - 2019/03/22 Member of the organising committee of the advanced course " Being a bio-entrepeneur" (2019/03/04 - 2019/03/22) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/04/02 - 2018/04/20 Member of the organising committee of the advance course " Being a bio-entrepeneur" (2018/04/02 - 2018/04/20)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/05/15 - 2017/06/02 Member of the organising committee of the advanced course of "Molecular and cellular analysis: essencial toolkit for in vitro cell cultures, gene expression and microscopy" (2017/05/15 - 2017/06/02)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/10 - 2017/05/26 Organization of the XV MEETING SPN 2017 (2017/05/25 - 2017/05/26)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal
2017/04/26 - 2017/05/12 Member of the organising committee of the advanced course of "Advanced Hands-on the Rodent Brain: from intracellular trafficking to brain connectome" (2017/04/26 - 2017/05/12)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/04/18 - 2016/04/29 Member of the organising committee of the advanced course of "Epigenetics – from mechanisms to disease" (2016/04/18 - 2016/04/29)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/03/10 - 2016/03/14 Member of the organising committee of the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" (2016/03 - 2016/03)
Other
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/03/02 - 2015/03/13 Member of the organising committee of the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" (2015/03 - 2015/03)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2013/10 - 2014/10 International EMBO Workshop on Epigenetic plasticity: Implications in neural (dys)function (2014/10/22 - 2014/10/25)
Workshop (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/03/10 - 2014/03/14 Member of the organising committee of the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" (2014/03 - 2014/03)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2013/03/11 - 2013/03/15 Member of the organising committee of the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" (2013/03 - 2013/03)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/02/12 - 2012/02/16 Member of the organising committee of the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" (2012/03 - 2012/03)
Other (Member of the Organising Committee)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2011 - 2011 Laboratory Animal Science Course - FELASA C
Other
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/12/14 Thesis opponent of the PhD student Nicolas Blin, Thesis title “Role of adult-born dentate neurons in the resilience to cognitive aging”. PhD in Neurosciences, Université of Bordeaux, INSERM, France.
(Thesis) Main arguer
 Nicolas Blin (PhD)
Université de Bordeaux, France
2023/11/20 Thesis opponent of the MSc student Vitorino Dias, Thesis title “Safinamide Therapeutical Effects: Seeking for a diseasemodifying strategy for Parkinson’s Disease”. Master in Metabolism – Biopathology and Experimental, Faculty of Medicine, University of Porto, Porto, Portugal.
(Thesis) Main arguer
 Vitorino Dias (Master)
Universidade do Porto, Portugal
2023/10/12 Thesis opponent of the PhD student Giuseppe Cammarata, Thesis title “Neurodevelopment effects of valproic acid exposure in human brain organoids”. PhD in Experimental Biology and Biomedicine, University of Coimbra, Coimbra, Portugal.
(Thesis) Main arguer
 Giuseppe Cammarata (PhD)
Universidade de Coimbra, Portugal
2023/03/22 Thesis opponent of the MSc student Rachele Matsagani, Thesis title “Extracellular vesicles as mediators of stress-driven pathology”. Master in Neurosciences, Universitá degli studi di Trieste, Trieste, Italy.
(Thesis) Main arguer
 Rachele Matsagani (Master)
Università degli Studi di Trieste, Italy
2022/10/11 Thesis opponent of the MSc student Helena Margarida Teixeira Ferreira, Thesis title “Mother-offspring relationship in autism spectrum disorder: influence on development and behavior”. Master in Biomedical Research, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
(Thesis) Main arguer
 Helena Margarida Teixeira Ferreira (Master)
Universidade de Coimbra, Portugal
2022/09/13 Thesis opponent of the PhD student Rui Miguel Silva Rodrigues, Thesis title “Catalysing brain plasticity through adult neural stem cell modulation: the role of cannabinoids and neurotrophic factors”. PhD in Biomedical Sciences, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
(Thesis) Main arguer
 Rui Miguel Silva Rodrigues (PhD)
Universidade de Lisboa, Portugal
2022/01/14 Thesis opponent of the PhD student Teresa Correia Soares Canedo, Thesis title - Unveiling the cellular and molecular players involved in methemphetamine induced neuroinflammation: focus on astrocyte-microglial crosstalk.
(Thesis) Main arguer
 Teresa Correia Soares Canedo (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2021/12/21 Thesis opponent of the PhD student Cláudia Raquel Ferreira Marques, Thesis title - Assessing the therapeutic role of the secretome from mesenchymal stromal cells in genetic models of Parkinson's Disease based on the overexpression of alpha-synuclein.
(Thesis) Arguer
 Cláudia Raquel Ferreira Marques (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/10/22 Thesis opponent of the MSc student Rita caridade Silva, Thesis title - Combining Stem Cells Secretome and N-acetylcysteine to Parkinson's Disease modeling and repair
(Thesis) Arguer
 Rita Caridade Silva (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/07/15 Thesis opponent of the PhD student Ana Rita Gonçalves Gaspar, Thesis title - Microglia morphology and susceptibility to depression - impact of sex differences
(Thesis) Arguer
 Ana Rita Gonçalves Gaspar (PhD)
Universidade de Coimbra, Portugal
2021/01/08 Thesis opponent of the MSc student Cláudio Miguel Rodrigues Coelho, Thesis title “Cerebral organoids as a tool for studying the modulation of opioid receptors, as well as possible molecular and cellular changes in the brain”
(Thesis) Arguer
 Cláudio Miguel Rodrigues Coelho (Master)
Universidade do Minho, Portugal
2019/11/11 Thesis opponent of the PhD student João Carlos Lima Gonçalves, Thesis title “Dissecting the mechanisms of dynein recruitment to the nuclear envelope during neocortical development”.
(Thesis) Arguer
 João Carlos Lima Gonçalves (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/10/21 Thesis opponent of the MSc student Inês Moreira Ribeiro, Thesis title “Neuron-Microglia crosstalk under methamphetamine: exploring ligand-receptor pairs that may attenuate microglia reactivity”.
(Thesis) Main arguer
 Inês Moreira Ribeiro (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/04/02 Thesis opponent of the PhD student João Luís Vaz Lima da Silva, Thesis title “Unraveling the synaptic role of Rab35: implications for Alzheimer´s disease pathology”.
(Thesis) Arguer
 João Luís Vaz Lima da Silva (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/02/22 Thesis opponent of the student Vanessa Santos - PhD thesis with the title: Effect of methylphenidate on blood-brain barrier function in health and attention deficit hyperactivity disorder.
(Thesis) Arguer
 Vanessa Filipa Coelho Santos (PhD)
Universidade de Coimbra, Portugal
2018/02/01 Thesis opponent of the student Vanessa Sardinha - PhD thesis with the title: The influence of gliotransmission on higher cognitive functions
(Thesis) Arguer
 Vanessa Alexandra Morais Sardinha (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/02/01 Thesis opponent of the PhD student Mónica Susana Dias Morais, Thesis title “New insights on the interplay between psychopharmacology and neuroplasticity in psychiatric disorders”.
(Thesis) Arguer
 Mónica Susana Dias Morais (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/01/04 Thesis opponent of the the Master in Medicine of the student André Miguel Lopes Miranda with the thesis title: The role of phosphatidylinositol-3,5- bisphosphate in neuronal endolysosomal function: implications for Alzheimer’s disease
(Thesis) Arguer
 André Miguel Lopes Miranda (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/01/04 Thesis opponent of the the Master in Medicine of the student Egídio André Miranda Freitas with the thesis title: Impact of Human Mesenchymal Stem Cells Secretome combined with Pharmacotherapies on Brain Structure and Animal Behavior of Rat Model of Parkinson’s Disease
(Thesis) Arguer
 Egídio André Miranda Freitas (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/10/02 Thesis opponent of the student Célia Márcia Azevedo Soares - PhD thesis with the title: Fate of the earliest retinal ganglion cells during development of the visual system.
(Thesis) Arguer
 Célia Márcia Azevedo Soares (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09/22 Thesis opponent of the student Miguel Maria Restolho Mateus Pinheiro Master Master thesis with the title: Glucocorticoid effects in the developing hippocampus: A morphometric assessment
(Thesis) Main arguer
 Miguel Maria Restolho Mateus Pinheiro (Master)
Universidade de Coimbra, Portugal
2017/09/22 Thesis opponent of the student Tiago João dos Santos Reis Master Master thesis with the title: The role of cortico-striatal circuits in social hierarchies.
(Thesis) Main arguer
 Tiago João dos Santos Reis (Master)
Universidade de Coimbra, Portugal
2017/09/21 Thesis opponent of the student Marta Isabel Ferreira Leite Pereira Master Master thesis with the title: Characterization of Grasp2 Knockout mice as a new model of autism spectrum disorders.
(Thesis) Main arguer
 Marta Isabel Ferreira Leite Pereira (Master)
Universidade de Coimbra, Portugal
2017/07/11 Thesis non-opponent of the student Nuno Dinis Lopes Oliveira Alves - PhD thesis with the title: Adult neural plasticity in the pathophysiology of depression: new insights from an animal model of recurrence
Supervisor
 Nuno Dinis Lopes Oliveira Alves (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/04/20 Thesis opponent of the student Nuno Moguel de Jesus Machado - PhD thesis with the title: Role of the adenosinergic system in animal models of chronic stress and depression.
(Thesis) Arguer
 Nuno Moguel de Jesus Machado (PhD)
Universidade de Coimbra, Portugal
2017/04/05 Thesis opponent of the student António Manuel Carvalho da Silva - PhD thesis with the title: Neurobiology of the circadian clock: metabolism control and implications for Alzheimer's disease.
(Thesis) Arguer
 António Manuel Carvalho da Silva (PhD)
Universidade de Coimbra, Portugal
2017/03/29 Thesis opponent of the student Mónica Susana Dias Morais - PhD thesis with the title: New insights on the interplay between psychopharmacology and neuroplasticity in psychiatric disorders.
(Thesis) Arguer
 Mónica Susana Dias Morais (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/03/23 Thesis non-opponent of the student Cátia Sofia Carvalheiro Alves Master Master thesis with the title: Validation of an automated equipment for depression induction in a rodent model.
Supervisor
 Cátia Sofia Carvalheiro Alves (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2016/11/08 Thesis non-opponent of the student Eduardo Manuel Loureiro de Campos Master Master thesis with the title: The role of AP2gamma transcription factor in the modulation of adult glutamatergic neurogenesis in depression.
Supervisor
 Eduardo Manuel Loureiro de Campos (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/07/08 Thesis non-opponent of the student António Maria Restolho Mateus Pinheiro - PhD thesis with the title: Adult Hippocampal Neural Plasticity: Insights into its functional relevance in the stressed and depressed brain.
Supervisor
 António Maria Restolho Mateus Pinheiro (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/05/09 Thesis non-opponent of the student Patricia Carvalho Patricio - PhD thesis with the title: Molecular regulation of the hippocampal neurogenic niche in depression and by antidepressants: insights from an unpredictable chronic mild stress rat model.
Supervisor
 Patricia Carvalho Patricio (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/01/08 Thesis opponent of the the Master in Medicine of the student Ângela Soraia de Oliveira Mendes with the thesis title: PHARMACOLOGICAL EVALUATION OF THE EFFECT OF A REVERSIBLE INHIBITOR OF MONOAMINE OXIDASE A AND ITS ENANTIOMERS IN THE CONTROL OF PAIN AND COMORBID EMOTIONAL IMPAIRMENTS IN EXPERIMENTAL NEUROPATHY
(Thesis) Arguer
 Ângela Soraia de Oliveira Mendes (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/01/30 Thesis non-opponent of the student Fábio Gabriel Rodrigues Teixeira - PhD thesis with the title: Modulation of the Secretome of Mesenchymal Stem Cells for Central Nervous System Regenerative Medicine Applications.
Thesis Member
 Fábio Gabriel Rodrigues Teixeir (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/01/09 Thesis opponent of the Master student Ana Patrícia Dias Fernandes Rodrigues with the thesis title: STIMULATION OF D2 NEURONS IN THE NUCLEUS ACCUMBENS INCREASES MOTIVATION IN A MODEL OF IN UTERO EXPOSURE TO GLUCOCORTICOIDS
(Thesis) Arguer
 Ana Patrícia Dias Fernandes Rodrigues (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/01/09 Thesis opponent of the the Master in Medicine of the student João Miguel Carvalho da Costa with the thesis title: Cellular passages influence the Secretome of stem cells in the adipose tissue?
(Thesis) Arguer
 João Miguel Carvalho da Costa (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/01/07 Thesis opponent of the the Master in Medicine of the Student Luís André Santos Araújo with the thesis title: Effects of bone marrow-derived mesenchymal stem cells secretome on degenerative changes progression associated to massive rotator cuff tears.
(Thesis) Arguer
 Luís André Santos Araújo (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/09/07 Thesis oponnent of the Master student Mário Carvalho, Centro de Neurociências e Biologia Celular, Universidade de Coimbra
(Thesis) Main arguer
 Mário Carvalho (Master)
Universidade de Coimbra, Portugal

Association member

Society Organization name Role
2024/01 - Current Mediterranean Neuroscience Society (MNS) Council Member and Vice-Secretary
2019 - Current European College of Neuropsychopharmacology (ECNP) Member
2018 - Current European Behavioural Pharmacology Society (EBPS) Member
2012 - Current Portuguese Society of Neuroscience (SPN) Member
2010 - Current Society for Neurosciences Member
2003 - Current National Association of Biochemistry Member
2013 - 2015 EpiGeneSys - FP7 European Community-funded Network of Excellence Associate Member

Committee member

Activity description
Role 		Institution / Organization
2019 - Current Co-Founder of the European College of NeuroPsychopharmacolgy (ECNP) Thematic Network on Stress Resilience
Member
 European College of Neuropsychopharmacology, Netherlands
2021 - 2023 Member of the Scientific Programme Committee for the 38th ECNP Congress 2023
Member
 European College of Neuropsychopharmacology, Netherlands

Conference scientific committee

Conference name Conference host
2022 - 2023 36th ECNP Congress , Barcelona ECNP
2018/10 - 2019/05 XVI Meeting of the Portuguese Society for Neuroscience Universidade de Lisboa

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2009/09 - Current Cells and Molecules in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2009 - Current Functional and Organic Systems (SOFs) I in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2009 - Current Functional and Organic Systems (SOFs) II in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2009 - Current Functional and Organic Systems (SOFs) III in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2022/09 - 2023/06 Curricular Unit “Fundamentals of Medicine”, Degree of Medicine, School of Medicine, University of Minho, Braga, Portugal. Medicina (Licenciatura) Universidade do Minho, Portugal
2022/09 - 2023/06 Curricular Unit “Complementary pathways in medicine”, Degree of Medicine, School of Medicine, University of Minho, Braga, Portugal Medicina (Licenciatura) Universidade do Minho, Portugal
2022/09 - 2023/06 Curricular Unit “Biologic effects of Radiation”, Degree of Medical Physics, Department of Physics, University of Minho, Braga, Portugal Medicina (Licenciatura) Universidade do Minho, Portugal
2022/11/08 - 2022/11/08 Speaker in the advanced postgraduate course 15th Fundamentals in Neuroscience Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho, Portugal
2021/09 - 2022/06 Curricular Unit “Fundamentals of Medicine”, Degree of Medicine, School of Medicine, University of Minho, Braga, Portugal Medicina (Licenciatura) Universidade do Minho, Portugal
2021/09 - 2022/06 Curricular Unit “Complementary pathways in medicine”, Degree of Medicine, School of Medicine, University of Minho, Braga, Portugal. Medicina (Licenciatura) Universidade do Minho, Portugal
2021/09 - 2022/06 Curricular Unit “Biologic effects of Radiation”, Degree of Medical Physics, Department of Physics, University of Minho, Braga, Portugal Física Médica (Licenciatura) Universidade do Minho, Portugal
2022/03/07 - 2022/03/25 Speaker in the advanced postgraduate course "Being a bio-entrepreneur" (8th edition) (Pós-Graduação) Universidade do Minho, Portugal
2021 - 2021 Speaker in the advanced course "Being a bio-entrepeneur" (Pós-Graduação) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020 - 2020 Speaker in the advanced course "Being a bio-entrepeneur" (Pós-Graduação) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/03/04 - 2019/03/22 Speaker in the advanced course "Being a bio-entrepeneur" (2nd Edition) PhD in Applied Sciences (Doutoramento) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09/20 - 2018/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/04/02 - 2018/04/20 Speaker in the advance course "Being a bio-entrepeneur" Applied Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/02/19 - 2018/03/09 Speaker in the advanced course of "Hands-on the Rodent Brain: from intracellular trafficking to brain connectome" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09/20 - 2017/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/05/15 - 2017/06/02 Speaker in the advanced course of "Molecular and cellular analysis: essencial toolkit for in vitro cell cultures, gene expression and microscopy" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/04/26 - 2017/05/12 Speaker in the advanced course of "Advanced Hands-on the Rodent Brain: from intracellular trafficking to brain connectome" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/02/20 - 2017/02/20 Speaker in the advanced course of "Neuronal Circuits and Behavior" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra, Portugal
2016 - 2017 From the Clinic to Molecular Biology I in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2016/09/20 - 2016/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/07/23 - 2016/07/23 Speaker in the advanced course of Epigenomics of Metabolic Disease (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto Faculdade de Medicina, Portugal
2016/04/18 - 2016/04/29 Speaker in the advanced course of "Epigenetics – from mechanisms to disease" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/04/26 - 2016/04/26 Speaker in the advanced course of "Neuronal Circuits and Behavior" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra, Portugal
2016/03/10 - 2016/03/14 Speaker in the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/09/20 - 2015/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/05/19 - 2015/05/19 Speaker in the advanced course of "Neuronal Circuits and Behavior" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra, Portugal
2015/03/02 - 2015/03/13 Speaker in the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014 - 2015 Introduction to the Course of Medicine in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2014/09/20 - 2014/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/03/10 - 2014/03/14 Speaker in the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/01/28 - 2014/01/28 Speaker in the advanced course of "Neuronal Circuits and Behavior" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra, Portugal
2013/09/20 - 2013/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2013/03/11 - 2013/03/15 Speaker in the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2013/02/10 - 2013/02/10 Speaker in the advanced course of "An integrative approach to cell analyses" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012 - 2013 Fundamentals in Medicine in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2012/09/20 - 2012/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/02/12 - 2012/02/16 Speaker in the advanced course of "Stem Cells get practical: Approaches on stem cells isolation, characterization and differentiation" Health Sciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2011 - 2012 Introduction to the Course of Medicine in the Degree of Medicine Medicine (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2011/09/20 - 2011/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2010/09/20 - 2010/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2009/09/20 - 2009/09/20 Speaker in the advanced course of "Fundamentals of Neuroscience" Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2021 - 2023 Member of the Research Foundation Flanders (FWO) Review College
Member
 Universidade do Minho, Portugal Fonds Wetenschappelijk Onderzoek Vlaanderen
2019 - 2022 Scientific Reports Evaluator, Member of the Evaluation Committee for Final Scientific Reports of projects IC&DT 2019-2022| CA Experimental Biology and Biochemistry
Evaluator
 Fundação para a Ciência e Tecnologia (FCT), Portugal Fundação para a Ciência e Tecnologia (FCT)
2019 - 2019 Project Reviewer for the Graduate Women in Science (GWIS) National Fellowships Program, USA
Evaluator
 Graduate Women in Science, United States
2018 - 2018 Project reviewer for ERA-NET NEURON - NEURON JTC2018- Mental disorders
Evaluator
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2018 Project reviewer for the Research Foundation Flanders (FWO)
Evaluator
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Fonds Wetenschappelijk Onderzoek Vlaanderen
2015 - 2017 Project reviewer for the French National Research Agency (ANR)
Evaluator
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Agence nationale de la recherche
2014 - 2017 Project reviewer for the University of Bordeaux Postdoctoral IdEx Programme of Excellence
Evaluator
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Université de Bordeaux

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2019/12/11 Interview in the newspaper about the Prize from Nature Research Awards for Driving Global Impact 2019 - Brain Sciences. SemanárioV
2019/11/12 News in the newspaper about the Prize from Nature Research Awards for Driving Global Impact 2019 - Brain Sciences. Publico
2016/10/27 AP2gamma protein induces the production of new neurons Saúde Online
2016/10/26 AP2gamma protein induces the production of new neurons Atlas da Saúde
2016/10/26 AP2gamma protein induces the production of new neurons - study done by UMinho Antena Minho
2016/10/25 Portuguese Scientists discover how to produce new neurons TVI24
2016/10/23 Team from UMinho discover protein that induces the production of new neurons in the adult brain Agência Lusa
2011/09/30 University of Minho: Depression reduces the number of newborn neurons Correio do Minho
2009/09/15 Portuguese discover gene involved in the formation of neurons Público

Interview (tv / radio show)

Program Topic
2022/02/07 - 2022/02/07 Mentes que Brilham - Porto Canal The role of cell genesis in depression
2019/12/10 - 2019/12/10 TV program “Mentes que Brilham” of Porto Canal channel “Brain plasticity and Depression” related with the Prize from Nature Research Awards for Driving Global Impact 2019 - Brain Sciences.
2019/11/20 - 2019/11/20 Days of the Future program of the Antena 1 Radio "Brain plasticity and Depression” related with the Prize from Nature Research Awards for Driving Global Impact 2019 - Brain Sciences
2019/08/09 - 2019/08/09 UM I&D program of the RUM- Minho University Radio Brain plasticity and Depression” related with the Prize from Nature Research Awards for Driving Global Impact 2019 Brain Sciences.
2016/11 - 2016/11 TV program "Mentes que Brilham" of Porto Canal channel Interview about the role of AP2gamma in the production of new neurons in the adult brain
2009/03 - 2009/03 Consultório no Porto Canal Discovery of the gene AP2gamma that is involved in the generation of neurons

Journal scientific committee

Journal title (ISSN) Publisher
2023/03/01 - Current BOSN - Brain Organoids and Systems Neurosciences ( 2949-9216) Elsevier
2021 - Current Cells
2019 - Current European Journal of Neuroscience (1460-9568) Wiley (Blackwell Publishing)
2019 - Current Journal of Neural Transmission (1435-1463) Springer-Verlag
2018 - Current Frontiers in Neuroscience (1662-453X) Frontiers Media SA
2018 - Current International Journal of Neuroscience (1543-5245) Informa UK (Taylor & Francis)
2018 - Current Neurochemical Research (1573-6903) Springer-Verlag
2017 - Current ec neurology
2017 - Current Current Pharmacogenomics and Personalized Medicine (1875-6921) Bentham Science
2017 - Current Oncotarget (1949-2553) "Impact Journals, LLC "
2017 - Current Journal of Neuroendocrinology (1365-2826) Wiley (Blackwell Publishing)
2017 - Current Hippocampus (1098-1063) Wiley (John Wiley & Sons)
2017 - Current Journal of Neuroimmunology (0165-5728) Elsevier
2016 - Current Matters (2297-8240) Sciencematters
2016 - Current Molecular Psychiatry (1359-4184) Springer Nature
2016 - Current European Neuropsychopharmacology (0924-977X) Elsevier
2016 - Current Genes Brain & Behavior (1601-183X) Wiley (Blackwell Publishing)
2015 - Current Molecular Neurobiology (0893-7648) Springer-Verlag
2014 - Current PeerJ (2167-8359) PeerJ
2014 - Current PLoS ONE (1932-6203) Public Library of Science
2014 - Current Frontiers in Behavioral Neuroscience (1662-5153) Frontiers Media SA
2014 - Current Neuropharmacology (0028-3908) Elsevier
2014 - Current British Journal of Pharmacology (1476-5381) Wiley (Blackwell Publishing)
2014 - Current The International Journal of Neuropsychopharmacology (1469-5111) Oxford University Press
2014 - Current Stem Cells International (1687-9678) Hindawi Publishing Corporation (Sage-Hindawi Access to Research)
2009 - Current Advances in Biology (2314-7563) Hindawi Limited
2009 - Current CNS Neuroscience & Therapeutics (1755-5949) Wiley (Blackwell Publishing)
2014 - 2015 Frontiers in Cellular Neuroscience (1662-5102) Frontiers Media SA
Distinctions

Award

2022 SPN Best Manuscript Award
Sociedade Portuguesa de Neurociências, Portugal
2021 ECNP 2021 Citation Prize
European College of Neuropsychopharmacology, Netherlands
2019 Nature Research Awards for Driving Global Impact: 2019 Brain Sciences - runner up
2013 1st Prize of the 13th edition of the Young Entrepreneur Award
ANJE Associação Nacional de Jovens Empresários, Portugal
2011 Prize of "Young Entrepreneurs"
TecMinho Associação Universidade-Empresa para o Desenvolvimento, Portugal
2011 1º Prize of Business Ideas
TecMinho Associação Universidade-Empresa para o Desenvolvimento, Portugal
2009 Doktorandenpreis 2009 (Best PhD Prize)
Helmholtz Zentrum München Institut für Entwicklungsgenetik, Germany
2008 Best Poster Award in the Cortical Development Meeting, Crete, Greece
2007 Best Poster Award in the IBRO World Congress of Neuroscience, Melbourne, Australia

Other distinction

2013 Assistant Researcher grant from the Programa Operacional Regional do Norte (ON.2)/QREN
European Regional Development Fund, Belgium
2009 Post-doc fellowship
Fundação para a Ciência e Tecnologia (FCT), Portugal
2004 Erasmus Scholarship
Universidade de Coimbra, Portugal
2004 PhD fellowship
Fundação para a Ciência e Tecnologia (FCT), Portugal