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Paula Margarida Vidigal Soares Teixeira Ferreira completed her Degree in Pharmaceutical Sciences in 1989 by the Universidade de Coimbra, Portugal and the PhD in Organic Chemistry in 1996 by the Universidade do Minho, Portugal. She is an Associate Professor at Universidade do Minho, Escola de Ciências. She published more than 90 research articles in peer-reviewed journals and supervised or co-supervised more than 20 PhD and MSc thesis. She participated in several research projects and the last five years she was PI of an FCT (Fundação para a Ciência e Tecnologia) funded project and PI from the Universidade do Minho of a co-development project with ICNAS-P (Instituto de Ciências Nucleares Aplicadas à Saúde) funded by ANI (Agência Nacional de Inovação). The most frequent terms found in the context of scientific and technological output are: dehydropeptide; self-assembly; drug delivery; contrast agents; medical imaging; catechol based peptides; magnetogels; supramolecular hydrogel and non-proteinogenic amino acids.
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Identification

Personal identification

Full name
Paula Margarida Vidigal Soares Teixeira Ferreira
Gender
Female

Citation names

  • Ferreira, Paula
  • Paula M.T. Ferreira

Author identifiers

Ciência ID
6517-BF65-F57F
ORCID iD
0000-0002-3279-6731
Researcher Id
A-5274-2013
Scopus Author Id
55947741900

Email addresses

  • pmf@quimica.uminho.pt (Professional)

Telephones

Telephone
  • 253604055 (Professional)

Addresses

  • Departamento de Química, Universidade do Minho, Campus de Gualtar, 4710-500 Braga, 4710-500, Braga, Braga, Portugal (Professional)
  • Dept. of Chemistry, University of Minho, Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Professional)

Websites

  • cq.uminho.pt (Scholar)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
French Beginner (A1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
1992 - 1996/06/14
Concluded
 Química (Doutoramento)
Major in Química orgânica
Universidade do Minho, Portugal
"Síntese Peptídica: Aplicação de Métodos Electroquímicos" (THESIS/DISSERTATION)
 Aprovada por unânimidade com distinção e louvor
1985 - 1989
Concluded
 Ciências Farmacêuticas (Mestrado integrado)
Universidade de Coimbra, Portugal
 16
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2005/01/03 - Current Associate Professor (University Teacher) Universidade do Minho Escola de Ciências, Portugal
1996 - 2005 Assistant Professor (University Teacher) Universidade do Minho, Portugal
1992 - 1996 Assistant (University Teacher) Universidade do Minho, Portugal
1989 - 1992 Trainee Assistant (University Teacher) Universidade do Minho, Portugal
Projects

Contract

Designation Funders
2022/10/01 - 2025/12/31 Aumento da sustentabilidade produtiva no setor das algas
PRR/BioEconomiaAzul/WP5/CEB
Researcher
Universidade do Minho, Portugal
Ongoing
2021/10/01 - 2025/12/31 Plataforma de Valorização, Industrilização e Inovação comercial para o Agro-alimentar
PRR n.º 37
Researcher
Universidade do Minho, Portugal
2020/01/01 - 2023/12/31 Projeto Estratégico CQ-UM 2020-2023 UIDP/00686/2020
UIDP/00686/2020
Researcher
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2021/01/01 - 2023/06/30 New imaging biomarkers in the assessment of chronic total coronary occlusion (Novos biomarcadores de imagem na avaliação das oclusões coronárias crónicas totais)
BioImage2CTO - 39698
Principal Investigador at the University of Minho
ICNAS-P, Portugal

Universidade do Minho, Portugal

Universidade de Coimbra, Portugal
Agência Nacional de Inovação SA
Concluded
2018/09/15 - 2022/03/14 Self-assembled minimalist peptide hydrogels inspired by mussel adhesive proteins for biomedical applications
PTDC/QUI-QOR/29015/2017
Principal investigator
Universidade do Minho Centro de Química, Portugal

REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/02/13 - 2021/08/12 Programa Doutoral em Química; NORTE-08-5369- FSE-000033
NORTE-08-5369- FSE-000033
Team member
Universidade do Minho Departamento de Química, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2017/07 - 2021/03 Organic Residues Valorization: Production of Humic Substances (Interreg-Poctep 0366_RES2VALHUM_1_P)
0366_RES2VALHUM_1_P
Researcher
Universidade do Minho Centro de Química, Portugal

Lipor, Portugal

Braval, Portugal

Universidade de Santiago de Compostela, Spain

Sogama - Sociedade Galega do Medio Ambiente, S.A, Spain

CVAN - Centro de Valorización Ambiental del Norte S.L., Spain

Centro de Valorização de Resíduos, CVR, Portugal
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2019/01/01 - 2019/12/31 Projeto estratégico UID/QUI/00686/2019
UID/QUI/00686/2019
Researcher
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015/04/01 - 2018/12/31 Projeto estratégico UID/QUI/00686/2013
UID/QUI/00686/2013
Researcher
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - UI 686 - 2011-2012
PEst-C/QUI/UI0686/2011
Universidade do Minho, Portugal

Universidade do Minho Centro de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2012 Interaction of new fluorescent biologically active heterocyclic compounds with DNA, lipid membranes and membrane proteins
PTDC/QUI/81238/2006
Researcher
Universidade do Minho Centro de Física, Portugal

Universidade do Minho Centro de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/01/01 - 2011/12/31 Target nanoconstructs for multimodal medical molecular imaging
PTDC/QUI/70063/2006)
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Minho Centro de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2006/01/02 - 2008/12/31 Metal-assisted synthesis and cyclization of new biologically active and/or fluorescent aryl or heteroarylamino acid derivatives
POCI/QUI/59407/2004
Researcher
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001/01/02 - 2003/12/31 Synthesis of non-proteinogenic amino acids with biological and/or photochromic activities
POCTI/1999/QUI/32689
Researcher
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Veloso, S.R.S; Ferreira, Paula; Andrade, Raquel G. D.; Cardoso, Beatriz; Rodrigues, Ana Rita O.; Castanheira, Elisabete M. S.. "Progress in multifunctional and multimodal biomaterials for therapeutic applications". In Advances in Biomedical Research, edited by Ikhmayies, S. J.. New York City, United States: Springer Publishing, 2024.
    Accepted
  2. Ferreira, Paula; Sérgio Rafael Silva Veloso; Elisabete Maria dos Santos Castanheira Coutinho; Paulo José Gomes Coutinho; José Alberto Martins. Corresponding author: Sérgio Rafael Silva Veloso. "Advances in Nanotheranostics with Plasmonic and Magnetic Nanoparticles". In Nanoparticles for Brain Drug Delivery, edited by Carla Vitorino; Andreia Jorge; Alberto A.C.C. Pais, 315-345. New York, United States: Jenny Stanford Publishing (Taylor & Francis Group), 2021.
    Published
  3. Paula M.T. Ferreira; Luís Miguel Oliveira Sieuve Monteiro. Corresponding author: Paula M.T. Ferreira. "N, N-diprotected dehydroamino acid derivatives: Versatile substrates for the synthesis of novel amino acids". In TARGETS IN HETEROCYCLIC SYSTEMS, edited by Orazio A. Attanasi; Domenico Spinelli, 152-175. Rome, Italy: Societa Chimica Italiana, 2006.
    Published
  4. Ferreira, Paula; Abreu, A.S.; Queiroz, M.-J.R.P.. "Palladium-catalysed borylation and suzuki coupling (BSC) to obtain ß-benzo[B]thienyldehydroamino acid derivatives". In Catalysts for Fine Chemical Synthesis: Metal Catalysed Carbon-Carbon Bond-Forming Reactions, edited by Stanley M. Roberts; Jianliang Xiao; John Whittall; Tom E. Pickett, 60-64. John Wiley & Sons, Ltd, 2004.
    Published
Conference abstract
  1. Valéria Gomes; Sérgio R.S. Veloso; hilliou, loic; Paula M.T. Ferreira; Castanheira, Elisabete M. S.. "Versatile magneto-plasmonic composites based on dehydropeptide hydrogels for multimodal cancer therapy". Paper presented in Sorrento 2013 ¿ Sorrento 2023: A Decade of Peptide Materials, Sorrento, 2023.
    Published
  2. Amorim, C.; Peter J. Jervis; Juliana Andrade; Paula M.T. Ferreira; José A. Martins. "Boolaamphiphilic dehydrodipeptide hydrogels for drug delivery applications (10.21814/1822.70576)". Paper presented in II Symposium on Applied Biochemistry, 2021.
  3. Helena Vilaça; Paula M.T. Ferreira. "Synthesis of new cyclic RGD peptides by click chemistry". Paper presented in 2º Encontro nacional de Química Terapêutica, Coimbra, 2010.
Conference paper
  1. Paula M. T. Ferreira; Peter J. Jervis; Inês Baptista; Luciana Martins; David M. Pereira; José A. Martins. Corresponding author: Peter J. Jervis. "Hydrogels and Nanostructures Formed from Ciprofloxacin Peptide Conjugates". Paper presented in 4th International Online Conference on Nanomaterials, 2023.
    Published • 10.3390/IOCN2023-14493
  2. Paula M. T. Ferreira; André Carvalho; José A. Martins. Corresponding author: André Carvalho. "New 2,6-Bis(5-phenyloxazolyl)pyridine Ligands for Luminescent LnIII Complexes". Paper presented in The 26th International Electronic Conference on Synthetic Organic Chemistry, 2022.
    Published • 10.3390/ecsoc-26-13714
  3. Ferreira, Paula; Veloso, Sérgio; Martins, José; Coutinho, Paulo; Castanheira, Elisabete. Corresponding author: Veloso, Sérgio. "Core-shell magnetic-plasmonic nanoparticles enclosed in a biocompatible dehydropeptide-based hydrogel containing lysine". Paper presented in Fourth Internacional Conference on Applications of Optics and Photonics, Lisbon, 2019.
    Published • 10.1117/12.2527184
  4. Paula M.T. Ferreira; A. C. Silva; P. Rocha; J. Antelo; F. Bento; P. Bettencourt; S. Fiol; et al. "Characterization of organic matter at different stages of a composting process". Paper presented in 5th International Conference WASTES: Solutions, Treatments and Opportunities, Lisbon, 2019.
    Published
  5. Paula M.T. Ferreira; A. C. Silva; R. López; J. Antelo; S. Fiol; F. Macías; F. Bento; M.C. Paiva; M.F. Proença. "Influence of the feedstock material on the compost maturity, stability and reactivity". Paper presented in 5th International Conference WASTES: Solutions, Treatments and Opportunities , September 4th - 6th, 2019, Lisbon, 2019.
    Published
  6. Pereira, Goreti; Ferreira, Paula M. T.; Vilaca, Helena; Pereira, Goreti; Ferreira, Paula; Vilaça, Helena. "Synthesis of new dehydroamino acids using coppercatalyzed C-N couplings". Paper presented in 22nd American Peptide Symposium, San Diego, 2011.
  7. Ferreira, M. T.; Monteiro, S.; Castanheira, Elisabete M.S.; Lopes, C.; Pereira, G.; MONTEIRO, LUÍS S.; Ferreira, Paula; Pereira, Goreti; LOPES, CARLA. "Electrochemical reduction of beta-aryldehydroamino acid derivatives". Paper presented in 31st European Peptide Symposium, 2010.
    Published
  8. Ferreira, Paula; Maia, Hernâni L.S.; Monteiro, Luis S.. "High yield synthesis of heterocyclic beta-substituted alanine derivatives". Paper presented in 16th American Peptide Symposium, Minneapolis, 1999.
    Published
  9. Ferreira, Paula; Maia, Hernâni L.S.; Monteiro, Luis S.. "Stereoselective synthesis of dehydroaminobutyric acid". Paper presented in 1st International Peptide Symposium, Kyoto, 1998.
    Published
  10. Ferreira, Paula; Maia, Hernâni L.S.; Monteiro, Luís S.. "Preparative dehydration of serine and threonine in peptides". Paper presented in 25th European Peptide Symposium, Budapest, 1998.
    Published
  11. Ferreira, Paula; Maia, Hernâni L.S.; Rodrigues, Lígia M.. "New Synthesis of Dehydroalanine Derivatives". Paper presented in 24th European Peptide Symposium, Edinburgh, 1998.
    Published
  12. Ferreira, Paula; Maia, Hernâni L.S.; Monteiro, Luís S.. "Efficient preparation of dehydroalanine derivatives". Paper presented in 1st International Peptide Symposium, Kyoto, 1998.
    Published
  13. Ferreira, Paula; Maia, Hernâni L.S.. Corresponding author: Ferreira, Paula. "Selective Cleavage of Protecting Groups in Arginine". Paper presented in 23rd European Peptide Symposium, Braga, 1994.
    Published
  14. Ferreira, Paula; Maia, Hernâni L. S.; Monteiro, Luís S.; Rodrigues, Lígia M.. "Preparative Cathodic Cleavage of Amine Protecting Groups". Paper presented in Biomed 1993 - Amino acids, Peptides, Proteins, Drug Discovery and Design, Patras, 1993.
    Published
  15. Ferreira, Paula; Maia, Hernâni L.S.; Rodrigues, Lígia M.. "Investigation of Amino Acid Racemization During Cathodic Cleavage of Protecting Groups". Paper presented in 21st European Peptide Symposium, Barcelona, 1990.
    Published
Conference poster
  1. Veloso, Sérgio; Ferreira, Paula; Correa-Duarte, Miguel; Castanheira, Elisabete M. S.. "Design of self assembled magnetic/plasmonic lipogels for multimodal cancer therapy". Paper presented in VI Annual Meeting CINBIO, 2023.
  2. Gomes, Valéria; Veloso, Sérgio; hilliou, loic; Ferreira, Paula; Castanheira, Elisabete M. S.. "New architectures in soft materials for combined cancer therapy". Paper presented in XXVI Encontro Galego Portugués de Química, 2022.
  3. Carolina Amorim; André Carvalho; Jervis, Peter J.; José A. Martins; Paula M.T. Ferreira. Corresponding author: Carolina Amorim. "Self-assembly of bolaamphiphiles based on dehydropeptides". Paper presented in XXVI Encontro Galego Portugués de Química, 2022.
  4. André Carvalho; Manuel Bañobre-López ; José A. Martins; Paula M.T. Ferreira. "Hydrogels featuring magnetic properties based on self-assembled dehydropeptides". Paper presented in ChemBioGels 2021 - Advances in hydrogels for biomedical applications, 2021.
  5. Gomes, Valéria; Veloso, Sérgio; hilliou, loic; Jervis, Peter J; Ferreira, Paula; Castanheira, Elisabete M. S.. "New architectures in soft materials for combined cancer therapy: Multifunctional dehydrodipeptide-based hydrogels with magneto-plasmonic properties". Paper presented in ChemBioGels2021, 2021.
  6. Veloso, S.R.S; Miguel A. Correa-Duarte; Paula M.T. Ferreira; Elisabete M.S. Castanheira. "Implications of nanoparticles functionalization in supramolecular magnetogels for drug delivery". Paper presented in EuroNanoForum, 2021.
  7. Veloso, S.R.S; Miguel A. Correa-Duarte; Paula M.T. Ferreira; Castanheira, Elisabete M. S.. "Supramolecular magnetogels: Advances towards on-demand drug release". Paper presented in Encontro Ciência 2020, 2020.
  8. Veloso, S.R.S; Miguel A. Correa-Duarte; Paula M.T. Ferreira; Castanheira, Elisabete M. S.. "Magnetolipogels: a combined strategy for controlled drug release". Paper presented in Imaginenano2020 Online, 2020.
  9. Joana F.G. Silva; Veloso, S.R.S; Paulo J. G. Coutinho; Castanheira, Elisabete M. S.; J.A. Martins; Paula M.T. Ferreira. "Novel ultra short peptide hydrogel as a potential drug nanocarrier". Paper presented in Nanomed Europe 2019 - NME19, 2019.
  10. Veloso, S.R.S; Paula M.T. Ferreira; J.A. martins; Paulo J. G. Coutinho; Castanheira, Elisabete M. S.. "Core-shell magnetic-plasmonic nanoparticles enclosed in biocompatible hydrogels for multimodal cancer therapy". Paper presented in IV International Conference on Applications of Optics and Photonics ¿ AOP2019, 2019.
  11. Diana Brandão; Veloso, S.R.S; Castanheira, Elisabete M. S.; José A. Martins; Paula M.T. Ferreira. "Benzyloxycarbonyldehydropeptides hydrogelators for drug delivery". Paper presented in 4th Symposium on Medicinal Chemistry, 2019.
  12. Veloso, S.R.S; Beatriz D. Cardoso; Ana Rita O. Rodrigues; J. A. Martins; Paula M.T. Ferreira; Castanheira, Elisabete M. S.. "Magnetogels based on magnetic/plasmonic nanoparticles and self-assembled peptide hydrogels as drug nanocarriers". Paper presented in I Jornadas da Ciência, 2019.
  13. Veloso, S.R.S; Ana Rita O. Rodrigues; J. A. Martins; Paula M.T. Ferreira; Castanheira, Elisabete M. S.. "New magnetogels based on manganese ferrite nanoparticles and self-assembled peptide hydrogels as drug nanocarriers". Paper presented in NaNaX 8 ¿ Nanoscience with Nanocrystals International Conference, 2017.
  14. Rita Nanim; Vilaça, Helena; Paula M.T. Ferreira; José A. Martins. "Bis-dehydroamino acid derivatives as hydrogelators". Paper presented in 3rd Symposium on Medicinal Chemistry of University of Minho, 2017.
  15. Vilaça, Helena; Loic Hilliou; Cristovão F. Lima; José Alberto Martins; Paula M.T. Ferreira. "A new RGD dehydropeptide with hydrogelation properties". Paper presented in 3º Encontro Nacional de Química Terapêutica, 2012.
  16. Helena Vilaça; Goreti Pereira; José Alberto Martins; Paula M.T. Ferreira. Corresponding author: Helena Vilaça. "Synthesis and self-assembly of new N-protected dehydropeptides". Paper presented in 21st International Conference on Physical Organic Chemistry, 2012.
  17. Vieira, Tatiana F.; Ferreira, Paula. "Novos Hidrogéis peptídicos para aplicações biomédicas". Paper presented in II Encontro em Técnicas de Caracterização e Análise Química, 2012.
  18. Vilaça, Helena; Goreti Pereira; Jorge Fernandes; José Alberto Martins; Paula M.T. Ferreira. "Synthesis and triggered gelation of a new dehydropeptide". Paper presented in XXII Encontro Nacional da Sociedade Portuguesa de Química, 2011.
  19. Ferreira, Paula; Martins, Jose A.; Castanheira, Elisabete M. S.; Ferreira, Miguel F.; Pereira, Goreti. "Synthesis of new 2,6-bis-(oxazole)pyridine ligand as a sensitizer for luminescent Ln(III) complexes". Paper presented in 17th European Symposium on Organic Chemistry, 2011.
  20. Helena Vilaca; Pereira, Goreti; Fernandes, J.; Martins, J. A.; Ferreira, Paula. "Dehydropeptides N-Conjugated with Naproxen as Hydrogelators". Paper presented in 13th European Symposium on Organic Reactivity, 2011.
  21. Goreti Pereira; Elisabete M.S. Castanheira; Paula M.T. Ferreira; Luís S. Monteiro; Vilaça, Helena. "High yielding synthesis of oxazole-4-carboxylates from dehydroamino acid derivatives. Application as fluorescent markers for peptides". Paper presented in 31st European Peptide Symposium, 2010.
  22. Vilaça, Helena; Goreti Pereira; Paula M.T. Ferreira; Luís S. Monteiro. "Synthesis of new bis-amino acids derivatives". Paper presented in 46th International Conference on Medicinal Chemistry, 2010.
  23. Ferreira, Paula; Castanheira, Elisabete M. S.; MONTEIRO, LUÍS S.; Pereira, Goreti. "Synthesis of new fluorescent amino acids". Paper presented in 16th European Symposium on Organic Chemistry, 2009.
  24. Pereira, Goreti; Castanheira, E. M. S.; Ferreira, Paula M. T.; Queiroz, M.-J.R.P.; Castanheira, Elisabete M. S.; Ferreira, Paula; QUEIROZ, MARIA-JOÃO R. P. .. "Synthesis of new chemosensors for fluoride ion from dehydroamino acid derivatives". Paper presented in 16th European Symposium on Organic Chemistry, 2009.
Journal article
  1. Paula Margarida Vidigal Soares Teixeira Ferreira; Helena Vilaça; André Carvalho; Tarsila Castro; Elisabete M. S. Castanheira; Loic Hilliou; Ian Hamley; Manuel Melle-Franco; José A. Martins. Corresponding author: Paula Margarida Vidigal Soares Teixeira Ferreira. "Unveiling the Role of Capping Groups in Naphthalene N-Capped Dehydrodipeptide Hydrogels". Gels 9 6 (2023): 464. https://doi.org/10.3390/gels9060464.
    Open access • Published • 10.3390/gels9060464
  2. Ferreira, Paula; Daniela Correia da Silva; Peter J. Jervis; José A. Martins; Patrícia Valentão; David M. Pereira. Corresponding author: David M. Pereira. "Fisetin derivatives exhibit enhanced anti-inflammatory activity and modulation of endoplasmic reticulum stress". International Immunopharmacology 119 (2023): 110178-110178. http://dx.doi.org/10.1016/j.intimp.2023.110178.
    10.1016/j.intimp.2023.110178
  3. Paula M. T. Ferreira; Valéria Gomes; Sérgio R. S. Veloso; Miguel A. Correa-Duarte; Elisabete M. S. Castanheira. Corresponding author: Elisabete M. S. Castanheira. "Tuning Peptide-Based Hydrogels: Co-Assembly with Composites Driving the Highway to Technological Applications". International Journal of Molecular Sciences 24 1 (2023): 186. https://doi.org/10.3390/ijms24010186.
    Open access • Published • 10.3390/ijms24010186
  4. Paula M. T. Ferreira; Sérgio R. S. Veloso; Raquel G. D. Andrade; Valéria Gomes; Carlos O. Amorim; Vítor S. Amaral; Verónica Salgueiriño; et al. Corresponding author: Elisabete M. S. Castanheira. "Oxidative Precipitation Synthesis of Calcium-Doped Manganese Ferrite Nanoparticles for Magnetic Hyperthermia". International Journal of Molecular Sciences 23 22 (2022): 14145-14145. https://doi.org/10.3390/ijms232214145.
    Published • 10.3390/ijms232214145
  5. Paula M. T. Ferreira; Carlos B. P. Oliveira; Valéria Gomes; José A. Martins; Peter J. Jervis. Corresponding author: Peter J. Jervis. "Peptide-Based Supramolecular Hydrogels as Drug Delivery Agents: Recent Advances". Gels 8 11 (2022): 706-706. https://doi.org/10.3390/gels8110706.
    Published • 10.3390/gels8110706
  6. Paula M. T. Ferreira; Carlos B. P. Oliveira; Renato B. Pereira; David M. Pereira; Loic Hilliou; Tarsila G. Castro; José A. Martins; Peter J. Jervis. Corresponding author: Paula M. T. Ferreira. "Aryl-Capped Lysine-Dehydroamino Acid Dipeptide Supergelators as Potential Drug Release Systems". International Journal of Molecular Sciences 23 19 (2022): 11811-11811. https://doi.org/10.3390/ijms231911811.
    Open access • Published • 10.3390/ijms231911811
  7. Paula M. T. Ferreira; Sérgio R. S. Veloso; Valéria Gomes; Sérgio L. F. Mendes; Loic Hilliou; Renato B. Pereira; David M. Pereira; et al. Corresponding author: Elisabete M. S. Castanheira. "Plasmonic lipogels: driving co-assembly of composites with peptide-based gels for controlled drug release". Soft Matter 18 (2022): 8384-8397. https://doi.org/10.1039/D2SM00926A.
    10.1039/D2SM00926A
  8. Paula M. T. Ferreira; Carlos B. P. Oliveira; Sérgio R. S. Veloso; Elisabete M. S. Castanheira; Pedro R. Figueiredo; Alexandra T. P. Carvalho; Loic Hilliou; et al. Corresponding author: Peter J. Jervis. "An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration-prepared from a known folate receptor ligand". Soft Matter 18 (2022): 3955-3966. https://doi.org/10.1039/D2SM00121G.
    Published • 10.1039/D2SM00121G
  9. Paula M.T. Ferreira; Sérgio Rafael Silva Veloso; Ecem Tiryaki; Carlos Spuch; Hilliou, Loic; C. O. Amorim; V. S. Amaral; et al. Corresponding author: Castanheira, Elisabete M. S.. "Tuning the drug multimodal release through a co-assembly strategy based on magnetic gels". Nanoscale 14 (2022): 5488-5500. https://doi.org/10.1039/D1NR08158F.
    Published • 10.1039/D1NR08158F
  10. Ferreira, Paula; Carolina Amorim; Sérgio R. S. Veloso; Elisabete M. S. Castanheira; Loic Hilliou; Renato B. Pereira; David M. Pereira; José A. Martins; Peter J. Jervis. Corresponding author: Ferreira, Paula. "Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems". Gels 7 2 (2021): 52-52. https://doi.org/10.3390/gels7020052.
    Open access • Published • 10.3390/gels7020052
  11. Paula M.T. Ferreira; Jervis, Peter J.; Hilliou, Loic; Pereira, Renato B.; David M. Pereira; José A. Martins. Corresponding author: Jervis, Peter J.. "Evaluation of a Model Photo-Caged Dehydropeptide as a Stimuli-Responsive Supramolecular Hydrogel". Nanomaterials 11 3 (2021): 704-704. https://doi.org/10.3390/nano11030704.
    Open access • Published • 10.3390/nano11030704
  12. Paula M. T. Ferreira; Peter J. Jervis; Carolina Amorim; Teresa Pereira; José A. Martins. Corresponding author: Peter J. Jervis. "Dehydropeptide Supramolecular Hydrogels and Nanostructures as Potential Peptidomimetic Biomedical Materials". International Journal of Molecular Sciences 22 5 (2021): 2528. https://doi.org/10.3390/ijms22052528.
    Open access • Published • 10.3390/ijms22052528
  13. Ferreira, Paula; Veloso, Sérgio R.S.; Jervis, Peter J.; Silva, Joana F.G.; Hilliou, Loic; Moura, C.; Pereira, David M.; et al. Corresponding author: Ferreira, Paula. "Supramolecular ultra-short carboxybenzyl-protected dehydropeptide-based hydrogels for drug delivery". Materials Science and Engineering: C 122 (2021): 111869. https://doi.org/10.1016/j.msec.2021.111869.
    Published • 10.1016/j.msec.2021.111869
  14. Paula M. T. Ferreira; Sérgio R. S. Veloso; Joana F. G. Silva; Loic Hilliou; Cacilda Moura; Paulo J. G. Coutinho; José A. Martins; et al. Corresponding author: Elisabete M. S. Castanheira. "Impact of Citrate and Lipid-Functionalized Magnetic Nanoparticles in Dehydropeptide Supramolecular Magnetogels: Properties, Design and Drug Release". Nanomaterials 11 1 (2020): 16-16. https://doi.org/10.3390/nano11010016.
    Open access • Published • 10.3390/nano11010016
  15. Paula M. T. Ferreira; Carolina Amorim; Peter J. Jervis; Juliana Andrade; José A. Martins. Corresponding author: Carolina Amorim. "Synthesis and Characterisation of Dimeric Bolaamphiphilic Dehydrodipeptides for Biomedical Applications". Materials Proceedings 4 1 (2020): 36-36. https://doi.org/10.3390/IOCN2020-07994.
    Open access • Published • 10.3390/IOCN2020-07927
  16. Paula M. T. Ferreira; Sérgio R. S. Veloso; Raquel G. D. Andrade; Beatriz C. Ribeiro; André V. F. Fernandes; A. Rita O. Rodrigues; J. A. Martins; Paulo J. G. Coutinho; Elisabete M. S. Castanheira. Corresponding author: Elisabete M. S. Castanheira. "Magnetoliposomes Incorporated in Peptide-Based Hydrogels: Towards Development of Magnetolipogels". Nanomaterials 10 9 (2020): 1702-1702. https://doi.org/10.3390/nano10091702.
    Open access • Published • 10.3390/nano10091702
  17. Ferreira, Paula; Moreira, R.; Jervis, Peter J; Carvalho, A; Martins, J. A.; Valentão, P.; Andrade, P. B.; Pereira, D. M.. Corresponding author: Pereira, D. M.. "Biological Evaluation of Naproxen Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors". Pharmaceutics 12 (2020): 122-122. http://dx.doi.org/10.3390/pharmaceutics12020122.
    Published • 10.3390/pharmaceutics12020122
  18. Ferreira, Paula; Veloso, Sérgio R. S.; Martins, J.A.; Hilliou, loic; Amorim, C. O.; Pereira, D.M.; Amaral, V. S.; et al. Corresponding author: Castanheira, E. M. S.. "Dehydropeptide-based plasmonic magnetogels: a supramolecular composite nanosystem for multimodal cancer therapy". Journal of Materials Chemistry B 8 (2020): 45-64. http://dx.doi.org/10.1039/c9tb01900f.
    Published • 10.1039/c9tb01900f
  19. Paula M. T. Ferreira; Peter J. Jervis; Carolina Amorim; Teresa Pereira; José A. Martins. Corresponding author: Paula M. T. Ferreira. "Exploring the properties and potential biomedical applications of NSAID-capped peptide hydrogels". Soft Matter 16 (2020): 10001-10012. https://doi.org/10.1039/D0SM01198C.
    Published • 10.1039/D0SM01198C
  20. Paula M. T. Ferreira; Sérgio R. S. Veloso; Carlos A. B. Magalhães; Ana Rita O. Rodrigues; H. Vilaça; Maria-João R. P. Queiroz; J. A. Martins; Paulo J. G. Coutinho; Elisabete M. S. Castanheira. Corresponding author: Elisabete M. S. Castanheira. "Novel dehydropeptide-based magnetogels containing manganese ferrite nanoparticles as antitumor drug nanocarriers". Physical Chemistry Chemical Physics 21 (2019): 10377-10390. https://doi.org/10.1039/C9CP00352E.
    10.1039/C9CP00352E
  21. Ferreira, Paula; Carvalho, André; Gallo, Juan; Pereira, David; Valentão, Patrícia; Andrade, Paula; Hilliou, Loic; Bañobre-López, Manuel; Martins, José. Corresponding author: Ferreira, Paula. "Magnetic Dehydrodipeptide-Based Self-Assembled Hydrogels for Theragnostic Applications". Nanomaterials 9 4 (2019): 541-541. http://dx.doi.org/10.3390/nano9040541.
    Open access • 10.3390/nano9040541
  22. Ferreira, Paula; Veloso, Sérgio; Martins, J.; Coutinho, Paulo; Castanheira, Elisabete. Corresponding author: Castanheira, Elisabete. "Magnetogels: Prospects and Main Challenges in Biomedical Applications". Pharmaceutics 10 3 (2018): 145-145. http://dx.doi.org/10.3390/pharmaceutics10030145.
    Open access • Published • 10.3390/pharmaceutics10030145
  23. Ferreira, Paula; Videira, Romeu A.; Andrade, Paula B.; Monteiro, Luís S.; Valentão, Patrícia; Pereira, David M.. Corresponding author: Pereira, David M.. "Toxicity and structure-activity relationship (SAR) of a,ß-dehydroamino acids against human cancer cell lines". Toxicology in Vitro 47 (2018): 26-37. http://dx.doi.org/10.1016/j.tiv.2017.10.027.
    Published • 10.1016/j.tiv.2017.10.027
  24. Ferreira, Paula; Monteiro, Luís S.; Oliveira, Sandra; Paiva-Martins, Fátima; Pereira, David M.; Andrade, Paula B.; Valentão, Patrícia. Corresponding author: Monteiro, Luís S.. "Synthesis and preliminary biological evaluation of new phenolic and catecholic dehydroamino acid derivatives". Tetrahedron 73 43 (2017): 6199-6209. https://doi.org/10.1016/j.tet.2017.09.012.
    Published • 10.1016/j.tet.2017.09.012
  25. Ferreira, Paula; Vilaça, Helena; Castro, Tarsila; Costa, Fernando M. G.; Melle-Franco, Manuel; Hilliou, Loic; Hamley, Ian W.; Castanheira, Elisabete M. S.; Martins, José A.. Corresponding author: Ferreira, Paula. "Self-assembled RGD dehydropeptide hydrogels for drug delivery applications". Journal of Materials Chemistry B 5 43 (2017): 8607-8617. http://dx.doi.org/10.1039/c7tb01883e.
    Published • 10.1039/c7tb01883e
  26. Ferreira, Paula; Abreu, Ana S.; Hermenegildo, Bruno F. C.; Queiroz, Maria João R. P.; Castanheira, Elisabete M. S.. Corresponding author: Castanheira, Elisabete M. S.. "Interaction of fluorescent quinolin-2-one and coumarin derivatives including dipeptides with lipid bilayers". RSC Advances 6 76 (2016): 72141-72148. http://dx.doi.org/10.1039/c6ra14376h.
    Published • 10.1039/c6ra14376h
  27. Ferreira, Paula; Vilaça, Helena; Hortelão, Ana C. L.; Castanheira, Elisabete M. S.; Queiroz, Maria-João R. P.; Hilliou, Loic; Hamley, Ian W.; Martins, José A.. Corresponding author: Ferreira, Paula. "Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers". Biomacromolecules 16 11 (2015): 3562-3573. http://dx.doi.org/10.1021/acs.biomac.5b01006.
    10.1021/acs.biomac.5b01006
  28. Ferreira, Paula; Fontes, André; Karimi, Shima; Helm, Lothar; André, João P.. Corresponding author: André, João P.. "PEGylated DOTA-AHA-Based GdIIIChelates: A Relaxometric Study". European Journal of Inorganic Chemistry 2015 29 (2015): 4798-4809. http://dx.doi.org/10.1002/ejic.201500688.
    Published • 10.1002/ejic.201500688
  29. Ferreira, Paula; Karimi, Shima; Fontes, André; Helm, Lothar; Yulikov, Maxim; André, João P.. Corresponding author: André, João P.. "Dinuclear DOTA-Based GdIIIChelates - Revisiting a Straightforward Strategy for Relaxivity Improvement". European Journal of Inorganic Chemistry 2015 9 (2015): 1579-1591. http://dx.doi.org/10.1002/ejic.201403159.
    Published • 10.1002/ejic.201403159
  30. Ferreira, Paula; Vilaça, H.; Pereira, G.; Castro, T. G.; Hermenegildo, B. F.; Shi, J.; Faria, T. Q.; et al. Corresponding author: Ferreira, Paula. "New self-assembled supramolecular hydrogels based on dehydropeptides". Journal of Materials Chemistry B 3 30 (2015): 6355-6367. http://dx.doi.org/10.1039/c5tb00501a.
    Published • 10.1039/c5tb00501a
  31. Ferreira, Paula; Ferreira, Miguel F.; Gonçalves, Janaina; Mousavi, Bibimaryam; Prata, Maria I. M.; Rodrigues, Sérgio P. J.; Calle, Daniel; et al. Corresponding author: Martins, José A.. "Gold nanoparticles functionalised with fast water exchanging Gd3+ chelates: linker effects on the relaxivity". Dalton Transactions 44 9 (2015): 4016-4031. http://dx.doi.org/10.1039/c4dt03210a.
    Published • 10.1039/c4dt03210a
  32. Ferreira, Paula; Vilaça, Helena; Micaelo, Nuno M.. Corresponding author: Ferreira, Paula. "New cyclic RGD peptides: synthesis, characterization, and theoretical activity towards avß3 integrin". Tetrahedron 70 35 (2014): 5420-5427. http://dx.doi.org/10.1016/j.tet.2014.06.121.
    Accepted • 10.1016/j.tet.2014.06.121
  33. Ferreira, Paula; Ferreira, M. F.; Pereira, G.; Martins, A. F.; Martins, C. I. O.; Prata, M. I. M.; Petoud, S.; et al. Corresponding author: Martins, J. A.. "Ln[DO3A-N-a-(pyrenebutanamido)propionate] complexes: optimized relaxivity and NIR optical properties". Dalton Trans. 43 8 (2014): 3162-3173. http://dx.doi.org/10.1039/c3dt52958d.
    Published • 10.1039/c3dt52958d
  34. Ferreira, Paula; Ferreira, Miguel F.; Pereira, Goretti; André, João P.; Prata, M. I. M.; Martins, José A.; Geraldes, Carlos F. G. C.. Corresponding author: Martins, José A.. "Ga[NO2A-N-(a-amino)propionate] chelates: synthesis and evaluation as potential tracers for 68Ga PET". Dalton Trans. 43 21 (2014): 8037-8047. http://dx.doi.org/10.1039/c4dt00386a.
    Published • 10.1039/c4dt00386a
  35. Ferreira, Paula; Pereira, Goreti; Castanheira, Elisabete M.S.; Schellenberg, Peter; Belsley, M.; Monteiro, Luís S.. Corresponding author: Castanheira, Elisabete M.S.. "Synthesis and photophysical studies of new pyrenylamino acids". Tetrahedron 69 48 (2013): 10254-10261. http://dx.doi.org/10.1016/j.tet.2013.10.035.
    Published • 10.1016/j.tet.2013.10.035
  36. Ferreira, Paula; de Sá, Arsénio; Bonnet, Célia S.; Geraldes, Carlos F. G. C.; Tóth, Éva; André, João P.. Corresponding author: Ferreira, Paula. "Thermodynamic stability and relaxation studies of small, triaza-macrocyclic Mn(ii) chelates". Dalton Transactions 42 13 (2013): 4522. http://dx.doi.org/10.1039/c2dt32496b.
    Published • 10.1039/c2dt32496b
  37. Ferreira, Paula; Monteiro, Luís S.; Pereira, Goreti; Castanheira, Elisabete M. S.; Frost, Christopher G.. Corresponding author: Ferreira, Paula. "Synthesis of Fluorescent Alanines by a Rhodium-Catalysed Conjugate Addition of Arylboronic Acids to Dehydroalanine Derivatives". European Journal of Organic Chemistry 2013 3 (2012): 550-556. https://doi.org/10.1002/ejoc.201201198.
    Published • 10.1002/ejoc.201201198
  38. Ferreira, Paula; Ferreira, Miguel F.; Martins, André F.; Martins, Catarina I. O.; Tóth, Éva; Rodrigues, Tiago B.; Calle, Daniel; et al. Corresponding author: Martins, José A.. "Amide conjugates of the DO3A-N-(a-amino)propionate ligand: leads for stable, high relaxivity contrast agents for MRI?". Contrast Media & Molecular Imaging 8 1 (2012): 40-49. http://dx.doi.org/10.1002/cmmi.1492.
    Published • 10.1002/cmmi.1492
  39. Ferreira, Paula; Abreu, Ana S.; Castanheira, Elisabete M.S.; Coutinho, Paulo J.G.; Queiroz, Maria-João R.P.; Vale-Silva, Luís A.; Pinto, Eugénia. Corresponding author: Castanheira, Elisabete M.S.. "Interaction of antitumoral fluorescent heteroaromatic compounds, a benzothienopyrrole and two thienoindoles, with DNA and lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 240 (2012): 14-25. http://dx.doi.org/10.1016/j.jphotochem.2012.05.009.
    Published • 10.1016/j.jphotochem.2012.05.009
  40. Ferreira, Paula; Pereira, G.; Vilaça, H.. Corresponding author: Ferreira, Paula. "Synthesis of new ß-amidodehydroaminobutyric acid derivatives and of new tyrosine derivatives using copper catalyzed C–N and C–O coupling reactions". Amino Acids 44 2 (2012): 335-344. http://dx.doi.org/10.1007/s00726-012-1337-4.
    Published • 10.1007/s00726-012-1337-4
  41. Ferreira, Paula; Pereira, Goreti; Ferreira, Miguel F.; Castanheira, Elisabete M. S.; Martins, José A.. Corresponding author: Ferreira, Paula. "Synthesis of 2,6-Bis(oxazolyl)pyridine Ligands for Luminescent LnIII Complexes". European Journal of Organic Chemistry 2012 21 (2012): 3905-3910. http://dx.doi.org/10.1002/ejoc.201200177.
    Published • 10.1002/ejoc.201200177
  42. Ferreira, Paula; Ferreira, M. F.; Mousavi, B.; Martins, C. I. O.; Helm, L.; Martins, J. A.; Geraldes, C. F. G. C.. Corresponding author: Martins, J. A.. "Gold nanoparticles functionalised with stable, fast water exchanging Gd3+ chelates as high relaxivity contrast agents for MRI". Dalton Transactions 41 18 (2012): 5472. http://dx.doi.org/10.1039/c2dt30388d.
    Published • 10.1039/c2dt30388d
  43. Ferreira, Paula; Hermenegildo, Bruno F.; Pereira, Goreti; Abreu, Ana S.; Castanheira, Elisabete M.S.; Queiroz, Maria-João R.P.. Corresponding author: Castanheira, Elisabete M.S.. "Phenanthrenyl-indole as a fluorescent probe for peptides and lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 221 1 (2011): 47-57. http://dx.doi.org/10.1016/j.jphotochem.2011.04.022.
    Published • 10.1016/j.jphotochem.2011.04.022
  44. Ferreira, Paula; Monteiro, Luís S.; Castanheira, Elisabete M.S.; Pereira, Goreti; Lopes, Carla; Vilaça, Helena. Corresponding author: Ferreira, Paula. "Electrochemical reduction of dehydroamino acids: synthesis and photophysical properties of ß,ß-diarylalanines". Tetrahedron 67 1 (2011): 193-200. http://dx.doi.org/10.1016/j.tet.2010.10.087.
    Published • 10.1016/j.tet.2010.10.087
  45. Ferreira, Paula; Abreu, A.S.; Castanheira, E.M.S.; Queiroz, M.-J.R.P.; Vale-Silva, L.A.; Pinto, E.. Corresponding author: Abreu, A.S.. "Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate". Nanoscale Research Letters 6 1 (2011): 1-6. https://dx.doi.org/10.1186/1556-276X-6-482.
    Published • 10.1186/1556-276X-6-482
  46. Ferreira, Paula; de Sá, Arsénio; Matias, Áurea A.; Prata, M. Isabel M.; Geraldes, Carlos F.G.C.; André, João P.. Corresponding author: André, João P.. "Gallium labeled NOTA-based conjugates for peptide receptor-mediated medical imaging". Bioorganic & Medicinal Chemistry Letters 20 24 (2010): 7345-7348. http://dx.doi.org/10.1016/j.bmcl.2010.10.059.
    Published • 10.1016/j.bmcl.2010.10.059
  47. Ferreira, Paula; Castanheira, Elisabete M.S.; Monteiro, Luís S.; Pereira, Goreti; Vilaça, Helena. Corresponding author: Ferreira, Paula. "A mild high yielding synthesis of oxazole-4-carboxylate derivatives". Tetrahedron 66 45 (2010): 8672-8680. http://dx.doi.org/10.1016/j.tet.2010.09.014.
    Published • 10.1016/j.tet.2010.09.014
  48. Ferreira, Paula; Monteiro, L. S.; Pereira, G.. Corresponding author: Ferreira, Paula. "Synthesis and electrochemical behaviour of ß-halodehydroamino acid derivatives". Amino Acids 39 2 (2010): 499-513. http://dx.doi.org/10.1007/s00726-009-0466-x.
    Published • 10.1007/s00726-009-0466-x
  49. Ferreira, Paula; Pereira, Goreti; Castanheira, Elisabete M. S.; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Paula. "Synthesis and Photophysical Studies of New Fluorescent Indole Derivatives Obtained from beta-Bromodehydroamino Acids. Interaction with Fluoride Anions". European Journal of Organic Chemistry 2010 3 (2010): 464-475. http://dx.doi.org/10.1002/ejoc.200900737.
    Published • 10.1002/ejoc.200900737
  50. Castanheira, E.M.S.; Abreu, A.S.; Queiroz, M.J.R.P.; Ferreira, P.M.T.. "Studies of encapsulation of a new potential antitumoral indole derivative in nanoliposomes for drug delivery applications". European Cells and Materials 20 SUPPL.3 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860903846&partnerID=MN8TOARS.
  51. Ferreira, Paula; Castanheira, Elisabete M.S.; Abreu, Ana S.; Queiroz, Maria-João R.P.; Coutinho, Paulo J.G.; Nazareth, Nair; Nascimento, M. São-José. Corresponding author: Castanheira, Elisabete M.S.. "Fluorescence properties of a potential antitumoral benzothieno[3,2-b]pyrrole in solution and lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 206 2-3 (2009): 220-226. http://dx.doi.org/10.1016/j.jphotochem.2009.07.007.
    Published • 10.1016/j.jphotochem.2009.07.007
  52. Ferreira, Paula; Pereira, Goreti; Abreu, Ana S.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Paula. "Synthesis and Photophysical Studies of a Pyrenylindole and a Phenalenoindole Obtained from Dehydroamino Acid Derivatives - Application as Fluorescent Probes for Biological Systems". European Journal of Organic Chemistry 2009 23 (2009): 3906-3916. http://dx.doi.org/10.1002/ejoc.200900351.
    Published • 10.1002/ejoc.200900351
  53. Ferreira, Paula; Monteiro, Luis S.; Coban, T.; Suzen, S.; Ferreira, P.M.; Monteiro, L.S.. Corresponding author: Suzen, S.. "Comparative effect ofN-substituted dehydroamino acids and a-tocopherol on rat liver lipid peroxidation activities". Journal of Enzyme Inhibition and Medicinal Chemistry 24 4 (2009): 967-971. http://dx.doi.org/10.1080/14756360802561162.
    Published • 10.1080/14756360802561162
  54. Ferreira, Paula; Martins, André F.; Ferreira, Miguel F.; Martins, José A.; Tóth, Éva; Geraldes, Carlos F.G.C.. Corresponding author: Martins, José A.. "Gd(DO3A-N-a-aminopropionate): a versatile and easily available synthon with optimized water exchange for the synthesis of high relaxivity, targeted MRI contrast agents". Chemical Communications 42 (2009): 6475. http://dx.doi.org/10.1039/b912201j.
    Published • 10.1039/b912201j
  55. Ferreira, Paula; Abreu, Ana S.; Castanheira, Elisabete M. S.; Monteiro, Luís S.; Pereira, Goreti; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Paula. "Pyrenylamino Acids: Synthesis, Photophysical and Electrochemical Studies". European Journal of Organic Chemistry 2008 34 (2008): 5697-5703. http://dx.doi.org/10.1002/ejoc.200800640.
    Published • 10.1002/ejoc.200800640
  56. Ferreira, Paula; Castanheira, Elisabete M. S.; Abreu, Ana S.; Carvalho, M. Solange D.; Queiroz, Maria-João R. P.. Corresponding author: Castanheira, Elisabete M. S.. "Fluorescence Studies on Potential Antitumoral Heteroaryl and Heteroannulated Indoles in Solution and in Lipid Membranes". Journal of Fluorescence 19 3 (2008): 501-509. http://dx.doi.org/10.1007/s10895-008-0439-6.
    Published • 10.1007/s10895-008-0439-6
  57. Ferreira, Paula; Queiroz, Maria-João R.P.; Begouin, Agathe; Pereira, Goreti. Corresponding author: Queiroz, Maria-João R.P.. "New synthesis of methyl 5-aryl or heteroaryl pyrrole-2-carboxylates by a tandem Sonogashira coupling/5-endo-dig-cyclization from ß-iododehydroamino acid methyl esters and terminal alkynes". Tetrahedron 64 47 (2008): 10714-10720. http://dx.doi.org/10.1016/j.tet.2008.08.105.
    10.1016/j.tet.2008.08.105
  58. Ferreira, Paula; Monteiro, Luís S.; Pereira, Goreti. Corresponding author: Ferreira, Paula. "Synthesis of Substituted Oxazoles fromN-Acyl-ß-hydroxyamino Acid Derivatives". European Journal of Organic Chemistry 2008 27 (2008): 4676-4683. http://dx.doi.org/10.1002/ejoc.200800602.
    Published • 10.1002/ejoc.200800602
  59. Ferreira, Paula; Queiroz, Maria-João R.P.; Abreu, Ana S.; Carvalho, M. Solange D.; Nazareth, Nair; São-José Nascimento, M.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation". Bioorganic & Medicinal Chemistry 16 10 (2008): 5584-5589. http://dx.doi.org/10.1016/j.bmc.2008.04.004.
    Published • 10.1016/j.bmc.2008.04.004
  60. Ferreira, Paula; Abreu, Ana S.; Queiroz, Maria João R.P.; Calhelha, Ricardo C.; Carvalho, M. Solange D.. Corresponding author: Ferreira, Paula. "New strategies for the synthesis of heteroannulated 2-pyridinones, substituted 2-quinolinones and coumarins from dehydroamino acid derivatives". Tetrahedron 64 22 (2008): 5139-5146. http://dx.doi.org/10.1016/j.tet.2008.03.057.
    Published • 10.1016/j.tet.2008.03.057
  61. Ferreira, Paula; Monteiro, L. S.; Queiroz, M.-J. R. P.; Pereira, G.. Corresponding author: Ferreira, Paula. "Synthesis of bis-amino acid derivatives by Suzuki cross-coupling, Michael addition and substitution reactions". Amino Acids 36 3 (2008): 429-436. http://dx.doi.org/10.1007/s00726-008-0095-9.
    Published • 10.1007/s00726-008-0095-9
  62. Ferreira, Paula; Queiroz, Maria-João R.P.; Castanheira, Elisabete M.S.; Carvalho, M. Solange D.; Abreu, Ana S.; Karadeniz, Hakan; Erdem, Arzum. Corresponding author: Queiroz, Maria-João R.P.. "New tetracyclic heteroaromatic compounds based on dehydroamino acids: photophysical and electrochemical studies of interaction with DNA". Tetrahedron 64 2 (2008): 382-391. http://dx.doi.org/10.1016/j.tet.2007.10.090.
    Published • 10.1016/j.tet.2007.10.090
  63. Ferreira, Paula; Monteiro, Luís S.; Pereira, Goreti; Ribeiro, Liliana; Sacramento, Joana; Silva, Liseta. Corresponding author: Ferreira, Paula. "Reactivity of Dehydroamino Acids and Dehydrodipeptides TowardsN-Bromosuccinimide: Synthesis of ß-Bromo- and ß,ß-Dibromodehydroamino Acid Derivatives and of Substituted 4-Imidazolidinones". European Journal of Organic Chemistry 2007 35 (2007): 5934-5949. http://dx.doi.org/10.1002/ejoc.200700669.
    Published • 10.1002/ejoc.200700669
  64. Ferreira, Paula; Queiroz, Maria-João R.P.; Abreu, Ana S.; Castanheira, Elisabete M.S.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis of new 3-arylindole-2-carboxylates using ß,ß-diaryldehydroamino acids as building blocks. Fluorescence studies". Tetrahedron 63 10 (2007): 2215-2222. http://dx.doi.org/10.1016/j.tet.2006.12.084.
    Published • 10.1016/j.tet.2006.12.084
  65. Ferreira, Paula; Monteiro, Luís S.. Corresponding author: Ferreira, Paula. "Synthesis and Reactivity of ß-Bromo-ß-Substituted Dehydroalanines". European Journal of Organic Chemistry 2006 14 (2006): 3226-3234. http://dx.doi.org/10.1002/ejoc.200600094.
    Published • 10.1002/ejoc.200600094
  66. Ferreira, Paula; Queiroz, Maria-João R. P.; Abreu, Ana S.; Oliveira, M. Manuel; Dubest, Roger; Aubard, Jean; Samat, André. Corresponding author: Queiroz, Maria-João R. P.. "A Thieno-2H-chromene a-Amino Acid Derivative: Synthesis and Photochromic Properties". Organic Letters 7 22 (2005): 4811-4814. http://dx.doi.org/10.1021/ol051378a.
    Published • 10.1021/ol051378a
  67. Ferreira, Paula; Abreu, Ana S.; Queiroz, Maria-João R. P.; Ferreira, Isabel C. F. R.; Calhelha, Ricardo C.; Estevinho, Letícia M.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of ß-Benzo[b]thienyldehydrophenylalanine Derivatives by One-Pot Palladium-Catalyzed Borylation and Suzuki Coupling (BSC) and Metal-Assisted Intramolecular Cyclization - Studies of Fluorescence and Antimicrobial Activity". European Journal of Organic Chemistry 2005 14 (2005): 2951-2957. http://dx.doi.org/10.1002/ejoc.200500040.
    Published • 10.1002/ejoc.200500040
  68. Ferreira, Paula; Venanzi, Mariano; Bocchinfuso, Gianfranco; Palleschi, Antonio; Abreu, Ana S.; Queiroz, Maria-João R.P.. Corresponding author: Venanzi, Mariano. "New fluorescent benzo[b]thienyl amino acid derivatives based on sulfanylphenyl benzo[b]thiophenes". Journal of Photochemistry and Photobiology A: Chemistry 170 2 (2005): 181-188. http://dx.doi.org/10.1016/j.jphotochem.2004.08.011.
    Published • 10.1016/j.jphotochem.2004.08.011
  69. Ferreira, Paula; Abreu, Ana S.; Monteiro, Luís S.; Queiroz, Maria-João R.P.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Letícia M.. Corresponding author: Ferreira, Paula. "Synthesis of pure stereoisomers of benzo[b]thienyl dehydrophenylalanines by Suzuki cross-coupling. Preliminary studies of antimicrobial activity". Tetrahedron 60 51 (2004): 11821-11828. http://dx.doi.org/10.1016/j.tet.2004.09.107.
    Published • 10.1016/j.tet.2004.09.107
  70. Ferreira, Paula; Abreu, Ana S.; Queiroz, Maria-João R. P.; Gatto, Emanuela; Venanzi, Mariano. Corresponding author: Queiroz, Maria-João R. P.. "Sonogashira Cross-Couplings of Dehydroamino Acid Derivatives and Phenylacetylenes". European Journal of Organic Chemistry 2004 19 (2004): 3985-3991. http://dx.doi.org/10.1002/ejoc.200400145.
    Published • 10.1002/ejoc.200400145
  71. Ferreira, Paula; Rodrigues, Anabela; Monteiro, Luís S.. Corresponding author: Monteiro, Luís S.. "Synthesis and reactivity of a 1,4-dihydropyrazine derivative". Tetrahedron 60 38 (2004): 8489-8496. http://dx.doi.org/10.1016/j.tet.2004.06.127.
    Published • 10.1016/j.tet.2004.06.127
  72. Ferreira, Paula; Abreu, Ana S.; Silva, Natália O.; Queiroz, Maria-João R.P.. Corresponding author: Queiroz, Maria-João R.P.. "Palladium-catalyzed borylation and Suzuki coupling (BSC) to obtain ß-substituted dehydroamino acid derivatives". Tetrahedron Letters 44 32 (2003): 6007-6009. http://dx.doi.org/10.1016/s0040-4039(03)01473-4.
    Published • 10.1016/s0040-4039(03)01473-4
  73. Ferreira, Paula; Maia, Hernâni L. S.; Monteiro, Luís S.. Corresponding author: Ferreira, Paula. "Synthesis of Non-Natural Amino Acids from N-(p-Tolylsulfonyl)-a,ß-didehydroamino Acid Derivatives". European Journal of Organic Chemistry 2003 14 (2003): 2635-2644. http://dx.doi.org/10.1002/ejoc.200300103.
    Published • 10.1002/ejoc.200300103
  74. Ferreira, Paula; Abreu, Ana S.; Silva, Natália O.; Queiroz, Maria-João R.P.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis and intramolecular cyclization of novel ß,ß-bis-(benzo[b]thienyl)dehydroalanine derivatives". Tetrahedron Letters 44 16 (2003): 3377-3379. http://dx.doi.org/10.1016/s0040-4039(03)00564-1.
    Published • 10.1016/s0040-4039(03)00564-1
  75. Ferreira, Paula; Abreu, Ana S.; Silva, Natália O.; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Paula. "Synthesis of Novel Amino Acids and Dehydroamino Acids Containing the Benzo[b]thiophene Moiety". European Journal of Organic Chemistry 2003 8 (2003): 1537-1544. http://dx.doi.org/10.1002/ejoc.200390212.
    Published • 10.1002/ejoc.200390212
  76. Ferreira, Paula; MAIA, H; MONTEIRO, L. Corresponding author: MONTEIRO, L. "Electrochemical synthesis of diaminodicarboxylic acid derivatives". Tetrahedron Letters 44 10 (2003): 2137-2139. http://dx.doi.org/10.1016/s0040-4039(03)00163-1.
    Published • 10.1016/s0040-4039(03)00163-1
  77. Ferreira, Paula; Abreu, A.S.; Silva, N.O.; Queiroz, M.-J.R.P.; Venanzi, M.. Corresponding author: Ferreira, Paula. "New ß,ß-Bis(benzo[b]thienyl)dehydroalanine Derivatives: Synthesis and Cyclization". European Journal of Organic Chemistry 2003 24 (2003): 4792-4796. https://dx.doi.org/10.1002/ejoc.200300394.
    Published • 10.1002/ejoc.200300394
  78. Ferreira, Paula; Maia, H.L.S.; Monteiro, L.S.. Corresponding author: Ferreira, Paula. "Synthesis of non-natural amino acids from N-(p-tolylsulfonyl)-a,ß-didehydroamino acid derivatives". European Journal of Organic Chemistry 14 (2003): 2635-2644. https://dx.doi.org/10.1002/ejoc.200300103.
    Published
  79. Ferreira, Paula; Silva, Natália O.; Abreu, Ana S.; Monteiro, Luís S.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis Using Suzuki Cross Couplings of Sulfur Analogues of Dehydrotryptophan with a Definite Stereochemistry". European Journal of Organic Chemistry 2002 15 (2002): 2524. https://doi.org/10.1002/1099-0690(200208)2002:15<2524::AID-EJOC2524>3.0.CO;2-W.
    Published • 10.1002/1099-0690(200208)2002:15<2524::aid-ejoc2524>3.0.co;2-w
  80. Ferreira, Paula; Maia, Hernâni L.S.; Monteiro, Luís S.. Corresponding author: Monteiro, Luís S.. "Synthesis of non-proteinogenic amino acids from N-(4-toluenesulfonyl)dehydroamino acid derivatives". Tetrahedron Letters 43 25 (2002): 4495-4497. http://dx.doi.org/10.1016/s0040-4039(02)00811-0.
    Published • 10.1016/s0040-4039(02)00811-0
  81. Ferreira, Paula; Maia, H.L.S.; Monteiro, L.S.. Corresponding author: Ferreira, Paula. "Synthesis of 2,3,5-substituted pyrrole derivatives". Tetrahedron Letters 43 25 (2002): 4491-4493. http://dx.doi.org/10.1016/S0040-4039(02)00810-9.
    Published • 10.1016/S0040-4039(02)00810-9
  82. Ferreira, Paula; Silva, N.O.; Abreu, A.S.; Monteiro, L.S.; Queiroz, M.-J.R.P.. Corresponding author: Queiroz, M.-J.R.P.. "Synthesis using Suzuki cross couplings of sulfur analogues of dehydrotryptophan with a definite stereochemistry". European Journal of Organic Chemistry 15 (2002): 2524-2528. http://dx.doi.org/10.1002/1099-0690(200208)2002:15<2524::AID-EJOC2524>3.0.CO;2-W.
    Published
  83. Ferreira, Paula; Maia, H.L.S.; Monteiro, L.S.; Sacramento, J.. Corresponding author: Maia, H.L.S.. "Michael addition of thiols, carbon nucleophiles and amines to dehydroamino acid and dehydropeptide derivatives". Journal of the Chemical Society. Perkin Transactions 1 23 (2001): 3167-3173. http://dx.doi.org/10.1039/b106487h.
    Published
  84. Ferreira, Paula; Maia, Hernâni L.S; Monteiro, Lui´s S; Sacramento, Joana. Corresponding author: Ferreira, Paula. "Synthesis of novel ß-substituted a,ß-dehydroamino acid derivatives". Tetrahedron Letters 41 39 (2000): 7437-7441. http://dx.doi.org/10.1016/s0040-4039(00)01271-5.
    Published • 10.1016/s0040-4039(00)01271-5
  85. Ferreira, Paula; Maia, Hernâni L. S.; Monteiro, Luís S.; Sacramento, Joana; Sebastião, Joana. Corresponding author: Maia, Hernâni L. S.. "Synthesis of ß-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives". Journal of the Chemical Society, Perkin Transactions 1 19 (2000): 3317-3324. http://dx.doi.org/10.1039/b003353g.
    Published • 10.1039/b003353g
  86. Ferreira, Paula; Alves, M.J.; Maia, H.L.S.; Monteiro, L.S.; Gilchrist, T.L.. Corresponding author: Gilchrist, T.L.. "Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester". Tetrahedron Letters 41 25 (2000): 4991-4995. http://dx.doi.org/10.1016/S0040-4039(00)00755-3.
    Published • 10.1016/s0040-4039(00)00755-3
  87. Ferreira, Paula; Maia, H.L.S.; Monteiro, L.S.; Sacramento, J.. Corresponding author: Ferreira, Paula. "Synthesis of novel ß-substituted a,ß-dehydroamino acid derivatives". Tetrahedron Letters 41 39 (2000): 7437-7441. http://dx.doi.org/10.1016/S0040-4039(00)01271-5.
    Published
  88. Ferreira, Paula; Maia, Hernâni L.S.; Monteiro, Luís S.. Corresponding author: Maia, Hernâni L.S.. "High yielding synthesis of heterocyclic ß-substituted alanine derivatives". Tetrahedron Letters 40 21 (1999): 4099-4102. http://dx.doi.org/10.1016/s0040-4039(99)00691-7.
    Published • 10.1016/s0040-4039(99)00691-7
  89. Ferreira, Paula; Maia, Hernâni L. S.; Monteiro, Luís S.; Sacramento, Joana. Corresponding author: Maia, Hernâni L. S.. "High yielding synthesis of dehydroamino acid and dehydropeptide derivatives". Journal of the Chemical Society, Perkin Transactions 1 24 (1999): 3697-3703. http://dx.doi.org/10.1039/a904730a.
    Published • 10.1039/a904730a
  90. Ferreira, Paula M.T.; Maia, Hernâni L.S.; Monteiro, Luís S.. "Efficient synthesis of dehydroamino acid derivatives". Tetrahedron Letters 39 51 (1998): 9575-9578. http://dx.doi.org/10.1016/s0040-4039(98)02164-9.
    10.1016/s0040-4039(98)02164-9
  91. Ferreira, Paula; Maia, H.L.S.; Monteiro, L.S.; Rebelo, M.R.J.; Rodrigues, L.. Corresponding author: Ferreira, Paula. "The use of electrochemical methods for deprotection during peptide synthesis". Review of Clinical Pharmacology and Pharmacokinetics, International Edition 9 2-3 (1995): 83-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029552354&partnerID=MN8TOARS.
    Published
Thesis / Dissertation
  1. Ferreira, Paula. "Síntese Peptídica: Aplicação de Métodos Electroquímicos". PhD, Universidade do Minho Centro de Química, 1996.

Other

Other output
  1. Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems. 2021. Ferreira, Paula; Carolina Amorim; Sergio R.S. Veloso; Elisabete M.S. Castanheira; Loic Hilliou; Renato B. Pereira; David M. Pereira; José A. Martins; Peter J. Jervis. https://doi.org/10.26434/chemrxiv.14261903.v1.
    10.26434/chemrxiv.14261903.v1
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/26 Design and Self-Assembly of Symmetrical Bolaamphiphiles Derived from Dehydrodipeptides: A Pathway to Tailored Nanostructures Sorrento 2013 – Sorrento 2023: A Decade of Peptide Materials
(Sorrento, Italy)
2023/10 Self assembled peptide-based photothermal hydrogels: cancer theranostic combining thermo-chemotherapy and MRI Sorrento 2013 – Sorrento 2023: A Decade of Peptide Materials
(Sorrento, Italy)
2023/03/21 "Peptide based magnetogels as new theranostic platforms", Keynote na 2nd Global Virtual Summit on: PHARMACEUTICAL & NOVEL DRUG DELIVERY SYSTEMS 20-22 de Março de 2023. 2nd Global Virtual Summit on: PHARMACEUTICAL & NOVEL DRUG DELIVERY SYSTEMS
2021/07/14 Dehydropeptide based nanostructures for biomedical applications; Keynote at the XXVII Encontro Nacional de Química, 14-16 Julho de 2021. XVII Encontro Nacional de Química, 14-16 Julho de 2021.
Sociedade Portuguesa de Química (Braga, Portugal)
2020/11 Self-Delivery' Using Anti-Inflammatory Hydrogels: Biological Evaluation of NSAID-Dehydrodipeptide Conjugates at the 2nd International Online-Conference on Nanomaterials. Session: Nanomedicine and Nanobiotechnology 2nd International Online-Conference on Nanomaterials. Session: Nanomedicine and Nanobiotechnology
2020/07/10 Supramolecular plasmonic magnetic gels for controlled drug delivery NanoBioMed Online Conference
2020/04/28 Magnetolipogels: a combined strategy for controlled drug release Imaginenano2020
(Bilbao, Spain)
2016/10 Dehydropeptide hydrogelators as new potential drug nanocarriers. Invited lecture at the Royal Society Theo Murphy International Scientific Meeting "Self-Assembled Peptides: From Nanostructure to Bioactivity", UK. Royal Society Theo Murphy International Scientific Meeting "Self-Assembled Peptides: From Nanostructure to Bioactivity"
Royal Society of Chemistry (Buckinghamshire, United Kingdom)
2013/06/13 New hydrogels based on small dehydropeptides for biomedical applications XXIII Encontro Nacional da SPQ
Sociedade Portuguesa de Química (Aveiro, Portugal)
2010/11/28 Synthesis of new cyclic RGD peptides by click chemistry 2º Encontro Nacional de Química Terapêutica
Sociedade Portuguesa de Química (Coimbra, Portugal)
2008/10/04 Synthesis of fluorescent heteroaromatic compounds using dehydroamino acids as building blocks, studies of DNA and biomenbranes interactions. Evaluation of antiproliferative effects on tumor cell lines EHRLICH II-2nd World Conference on Magic Bullets, Celebrating the 100th Anniversary of the Nobel Prize Award to Paul Ehrlich
German Association of Pharmaceutical Scientists (Numberg, Germany)
2008/09/11 A new synthesis of substituted pyrrole-2-carboxylates by a tandem Sonogashira coupling 5-endo-dig-cyclization from a beta-iododehydrophenylalanine and terminal alkynes 23rd European Colloquium on Heterocyclic Chemistry
(Antwerp, Belgium)
2008/03/06 Synthesis of pyrenyl amino acid derivatives XI Iberian Peptide Meeting (XI EPI),
(Santiago de Compostela, Spain)
2007/07/04 Reactivity of methyl esters of N-Boc-beta,beta-disubstituted dehydroamino acids towards the synthesis of lactams and lactones 11th European Symposium of Organic Reactivity
(Faro, Portugal)
2007/07/02 Reactivity of dehydroamino acid derivatives towards N-bromosuccinimide 11th European Symposium of Organic Reactivity
(Faro, Portugal)
2007/04/28 New tetracyclic antitumoral compounds including benzo[b]thiophene or dibenzothiophene units: synthesis, DNA interaction and biological studies First Iberic Meeting on Medicinal Chemistry: Anticancer Agents
(Régua, Portugal)
2006/09/03 Synthesis and DNA interaction of a new benzothienoindole XXII European Colloquium on heterocyclic Chemistry
(Bari, Italy)
2006/06/26 Dehydroamino acid derivatives: synthesis and cyclization 4th Transmediterranean Colloquium on Heterocyclic Chemistry
(Aveiro, Portugal)
2005/08/03 Synthesis of heterocyclic amino acid derivatives by palladium catalyzed borylation and Suzuki coupling (BSC) and metal-assisted C-N intramolecular cyclization 20th International Congress of heterocyclic Chemistry
(Palermo, Italy)
2004/01/29 Synthesis of bis-amino acids IX Iberian Peptide Meeting
(Porto, Portugal)
2004/01/28 Synthesis of novel beta,beta-disubstituted dehydroamino acids IX Iberian Peptide Meeting
(POrto, Portugal)
2003/12/02 Synthesis of bis-didehydroamino acids NZIC International Conference - Chemistry at the Interface
(Nelson, New Zealand)
2002/09/04 Synthesis of non-proteinogenic amino acids from N-(4-toluenesulfonyl)-dehydroalanine derivatives 27th European Peptide Symposium
European Peptide Society (Sorrento, Italy)
2002/02/07 N,N-Diacyldehydroamino acids: versatile reagents for the synthesis of new amino acids 8º Encontro Peptídico Ibérico
(Barcelona, Spain)
1995/07 Síntese do Fragmento Activo da Fibronectina. Aplicação de Métodos Electroquímicos 1° Encontro Nacional de Química Orgânica
Sociedade Portuguesa de Química (Braga, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/11/01 - Current Dehydropeptide based self-assembled injectable hydrogels for cardiac delivery
Co-supervisor of Carlos Oliveira
 Chemistry (PhD)
Universidade do Minho, Portugal
2023/01/02 - Current Plasmonic dehydropeptide-based lipogels: functionalizing post-surgical patches against melanoma recurrence and metastases
Co-supervisor of Alcinda Valéria Gomes Silva
 Programa Doutoral em Engenharia de Materiais (PhD)
Universidade do Minho, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
2022/01/01 - Current Model protocells based on peptide bolaamphiphiles – intermediates between self-assembled vesicles and cellular life
Supervisor of Maria Carolina Morais Amorim
 Química (PhD)
Universidade do Minho Departamento de Química, Portugal

Universidade do Minho Centro de Química, Portugal
2021/10/01 - Current New wound dressing materials based on anti-microbial dehydropeptide hydrogels
Supervisor of Inês Cerqueira Baptista
Química Medicinal (Master)
Universidade do Minho Departamento de Química, Portugal

Universidade do Minho Centro de Química, Portugal
2020/10/01 - Current Innovative peptide-based self-assembled theranostic hydrogel platform for combined MRI imaging and magnetic hyperthermia-activated cancer thermo-chemotherapy
Supervisor of André Filipe Gonçalves de Carvalho
 Química (PhD)
Universidade do Minho Centro de Química, Portugal

Universidade do Minho Departamento de Química, Portugal
2019 - 2023 Multifunctional nanogels containing magnetic/plasmonic nanoparticles for therapeutic applications
Co-supervisor of Sérgio Rafael da Silva Veloso
 Biofísica e Bionanossistemas (PhD)
Universidade do Minho, Portugal
2020/10 - 2022/02/09 Development of new supramolecular hypergelators based on dehydropeptide derivatives
Supervisor of Carlos Oliveira
 Química Medicinal (Master)
Universidade do Minho, Portugal
2020/10 - 2022/02 Multifunctional magnetic nanolipogels based on peptide hydrogels for application in combined cancer therapy
Co-supervisor of Alcinda Valéria Gomes Silva
 Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
2019/10 - 2021/03 Investigating bolaamphiphilic bis-dehydropeptide hydrogels as drug release systems
Supervisor of Maria Carolina Morais Amorim
 Química Medicinal (Master)
Universidade do Minho, Portugal
2017/03 - 2017/07 "Síntese de desidropéptidos derivados do ácido dipicolínico para a preparação de hidrogéis" - Projeto individual da Licenciatura em Química da Universidade do Minho.
Supervisor of Rita Nanim
 Química (Degree)
Universidade do Minho, Portugal
2017 - 2017 Síntese de um hidrogel peptídico contendo RGD e Avaliação como transportador do fármaco curcumina
Co-supervisor of Fernando Miguel Gonçalves Costa
 Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
2016 - 2017 Síntese de novos ligandos 2,6-bis-(5-feniloxazolil) piridina para preparação de complexos luminescentes de iões Ln(III)
Co-supervisor of Orlando Augusto Pinto de Oliveira
 Química Medicinal (Master)
Universidade do Minho, Portugal
2016/03 - 2016/07 "Desidropéptidos: estudos de self-assembly em hidrogéis e entrega controlada de fármacos" - Projeto individual da Licenciatura em Bioquímica da Universidade do Minho.
Co-supervisor of Carina Rego
 Bioquímica (Degree)
Universidade do Minho, Portugal
2016 - 2016 Síntese e caracterização de nanopartículas vetorizadas para células tumorais com possível aplicação na entrega controlada de fármacos
Co-supervisor of Eva Patrícia Quintas Pereira
 Química Medicinal (Master)
Universidade do Minho, Portugal
2015/03 - 2015/07 Novos Materiais têxteis baseados em hidrogéis de desidropéptidos - Projeto individual da Licenciatura em Química da Universidade do Minho, 2015.
Supervisor of Sandra Machado
 Química (Degree)
Universidade do Minho, Portugal
2015/03 - 2015/07 "Preparação e caraterização de complexos de iões metálicos com ligandos do tipo piridina-bis-oxazole" - Projeto individual da Licenciatura em Química da Universidade do Minho.
Co-supervisor of André Carvalho
 Química (Degree)
Universidade do Minho, Portugal
2011 - 2015 Synthesis of new peptide derivates that self-assemble into nanostructured hydrogels for biomedical applications
Supervisor of Maria Helena Pereira Vilaça
 Ciências (PhD)
Universidade do Minho, Portugal
2010 - 2015 Dota-based Ga(III) and Gd(III) chelates for medical imaging (PET, SPECT, and MRI)
Co-supervisor of André Filipe Gomes Soares Fontes
 Ciências (PhD)
Universidade do Minho, Portugal
2014/03 - 2014/07 "Síntese de oxazoles fluorescentes" - Projeto individual da Licenciatura em Química da Universidade do Minho.
Supervisor of Natália Nazaré Gonçalves Marques
 Química (Degree)
Universidade do Minho, Portugal
2012 - 2014 Synthesis of New Peptide Hydrogelators for Drug Delivery
Supervisor of Andrea Patrícia Ribeiro Martins
 Química Medicinal (Master)
Universidade do Minho, Portugal
2010 - 2014 Triazapolycarboxylate-based Ga(III) and Mn(II) chelates for medical imaging (PET, gamma-scintigraphy and MRI)
Co-supervisor of Arsénio Vasconcelos de Sá
 Ciências (PhD)
Universidade do Minho, Portugal
2008 - 2012 Dehydroamino acids as building blocks for the synthesis of new amino acid derivatives
Supervisor of Maria Goreti Carvalho Pereira
 Ciências (PhD)
Universidade do Minho, Portugal
2006 - 2010 Síntese de Benzo (b) Tienilaminoácidos e Ciclização Intramolecular C-n a Sistemas Heteroaromáticos Bi Ou Tricíclicos. Estudo de Fluorescência, Fotocromismo e Actividade Biológica
Supervisor of Ana Sofia Lemos Machado Abreu
 Ciências (PhD)
Universidade do Minho, Portugal
2006/03/02 - 2008/03/01 Metal-assisted synthesis and cyclization of new biologically active and/or fluorescent aryl or heteroarylamino acid derivatives - BI within the project POCI/QUI/59407/2004
Supervisor of Maria Goreti Carvalho Pereira
Universidade do Minho Centro de Química, Portugal
2003 - 2007 Síntese de Aminoácidos e Péptidos com Eventual Actividade Biológica
Co-supervisor of Joana Mendes Correia do Sacramento
 Ciências (PhD)
Universidade do Minho, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/10/21 - 2021/10/22 Organization of the first online internacional ChemBioGels2021 Symposium,, Advances in hydrogels for biomedical applications. President of the Organizing Committee (2021/10/21 - 2021/10/22)
Symposium (President of the Organising Committee)
 Universidade do Minho Centro de Química, Portugal
2013/05 - 2013/05 1st Symposium on Medicinal Chemistry of University of Minho. (2013 - 2013)
Symposium (President of the Organising Committee)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/02/24 Member of the jury of the PhD in Engenharia Biomédica of Fátima Alexandra Meira Machado titled "Dextrin: a platform for the development of drug delivery systems", Universidade do Minho.
(Thesis) Arguer
 Fátima Alexandra Meira Machado (PhD)
Universidade do Minho, Portugal
2022/12/12 Arguing member of the jury of the MSc in Medicinal Chemistry of Diana Isabel Sousa Alves titled "N-Substituted 5-amino-4-cyanopyrazoles: synthesis and reactivity studies", Universidade do Minho.
(Thesis) Arguer
 Diana Isabel Sousa Alves (Master)
Universidade do Minho, Portugal
2022/05/22 Arguing member of the jury of the PhD in Ciências Farmacêuticas, Química Farmacêutica of Ângela Cristina Barrôco Neves titled "ADVANCED MICROWAVE TECHNOLOGY IN RADIOPHARMACEUTICAL SYNTHESIS", Universidade de Coimbra
(Thesis) Main arguer
 Ângela Cristina Barrôco (PhD)
Universidade de Coimbra, Portugal
2021/11/02 Synthesis of new potential biological active compounds based on thiophene fused N-heterocycle scaffolds using cross-couplings, C-H activation and intra/intermolecular cyclizations
(Thesis) Arguer
 Juliana Patrícia de Moura Rodrigues (PhD)
Universidade do Minho Departamento de Química, Portugal
2021/07 New chromene derivatives: synthesis and anticancer activity"
(Thesis) Main arguer
 Diogo Costa (Master)
Universidade do Minho Centro de Química, Portugal
2019/12/06 Bioprospecting Aplysia sea hares as valuable sources of bioactive molecules.
(Thesis) Main arguer
 Renato Joel Barros Pereira (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/12 Síntese de heterociclos aromáticos com potencial atividade biológica
(Thesis) Main arguer
 Ana Beatriz Pereira de Sousa (Master)
Universidade do Minho Centro de Química, Portugal
2018 Multimodal actions of brown seaweed (Ochrophyta) bioactive compounds on inflammation and allergy network
(Thesis) Main arguer
 Mariana Nunes Barbosa (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 Studies on the synthesis of adenine derivatives and analogues as anticancer drug candidates
(Thesis) Main arguer
 Pedro Miguel Reis Figueiredo (Master)
Universidade do Minho, Portugal
2018 A reação de salicilaldeído com compostos de metileno ativado: caraterização de produtos e estudos de reatividade
(Thesis) Main arguer
 Diogo Alexandre Vilaça Lopes (Master)
Universidade do Minho Departamento de Química, Portugal
2017 Síntese de novas tieno[3,2-b]piridinas com potencial atividade biológica contendo 1,2,3-triazoles 1,4-dissubstituídos obtidos por reação "click" de ciclioadição azida-alquino catalisada por Cu(I) - CuAAC
(Thesis) Main arguer
 Juliana Patrícia de Moura Rodrigues (Master)
Universidade do Minho, Portugal
2016 Synthesis of novel heterocyclic compounds based on rational design and evaluation of their antitumor and antiangiogenic potential in human endothelial and tumor cell lines with tyrosine kinase membrane receptors as targets
Thesis Member
 Vera Alexandra Pereira Machado (PhD)
Universidade do Minho, Portugal
2016 Síntese de novos compostos heterocíclicos de S e/ou N com potencial aplicação em doenças do Sistema Nervoso Central usando como modelo de atividade e toxicidade o nematode Caenorhabditis elegans
(Thesis) Main arguer
 Ana Francisca Ferreira da Mota (Master)
Universidade do Minho, Portugal
2016 Identificação e quantificação dos produtos de eletrólises efetuadas em condições fisiológicas e estudo da sua atividade toxicológica utilizando leveduras como modelos celulares
(Thesis) Main arguer
 Isilda Catarina da Silva Amorim (Master)
Universidade do Minho, Portugal
2016 Aminoácidos não-proteinogénicos como antioxidantes
(Thesis) Main arguer
 Sandra Cristina Gomes Oliveira (Master)
Universidade do Minho, Portugal
2015 Towards antioxidant and antitumoral properties of wild medicinal plants traditionally used in Portugal: extracts, isolated flavonoids, and their human metabolites obtained by chemical synthesis
Thesis Member
 Cristina Rafaela dos Santos Albuquerque Guimarães (PhD)
Universidade do Minho, Portugal
2014 Important human metabolites of phenolic acids from diet with wild mushrooms: chemical synthesis and studies of their antioxidant, antitumor and antimicrobial properties
(Thesis) Arguer
 Sandrina Alves Heleno (PhD)
Universidade do Minho, Portugal
2014 Estudos Teóricos e estruturais para o desenvolvimento e síntese de aza-açúcares com atividade melhorada contra a Golgi a – manosidade II
(Thesis) Main arguer
 Bárbara Palma de Abreu Caldeira Pinto (Master)
Universidade do Minho, Portugal
2014 Síntese de novos derivados de tienopiridinas como potenciais antitumorais e antiangiogénicos tendo como alvos receptores membranares de tirosina cinase
(Thesis) Main arguer
 Joana Filomena Mimoso Silva de Campos (Master)
Universidade do Minho, Portugal
2012 Síntese e potenciais aplicações de novas porfirinas &#946;-funcionalizadas
(Thesis) Main arguer
 Nuno Miguel Malavado Moura (PhD)
Universidade de Aveiro, Portugal
2010 Síntese de Novos Compostos Heterocíclicos Derivados de Benzo(b)tiofenos e Tieno(3,2-b) Piridinas Usando Acoplamentos Catalisados por Metais.estudos de Actividade Biológica
(Thesis) Main arguer
 Manuel Ricardo Costa Calhelha (PhD)
Universidade do Minho, Portugal
2009 New heterocyclic bioactive fluorescent compounds: spectroscopic studies of DNA interactions and encapsulation in nanoliposomes
Thesis Member
 Maria Solange Dantas de Carvalho (PhD)
Universidade do Minho, Portugal
2003 Aclopamentos Cruzados Catalizados por Paládio (Cc e Cn) na Síntese de Compostos Tetracíclicos Heteroaromáticos Derivados Debenzo [e] Tiofenos
(Thesis) Main arguer
 Isabel Cristina Fernandes R. Ferreira (PhD)
Universidade do Minho, Portugal

Association member

Society Organization name Role
1994/06 - Current European Peptide Society Member of the European Peptide Society

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2015/06 - 2015/10 Member of the evaluation panel in the area of Chemistry of the FCT (Fundação para a Ciência e Tecnologia) 2015 PhD Studentships, PhD Studentships in Industry and Post-Doctoral fellowships.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia

Journal scientific committee

Journal title (ISSN) Publisher
2023/06/01 - Current Scientific Reports (2045-2322) Nature Publishing Group
2021 - Current Gels (2310-2861) MDPI

Other jury / evaluation

Activity description Institution / Organization
2023/02/27 - 2023/03/12 Reviewer of projects for the National Science Centre Poland, Funding scheme Sonata-18.
2022/04/03 - 2022/04/18 Reviewer of projects for the National Science Centre Poland, Funding scheme: OPPUS-22
2019/05 - 2019/05 Presidente do júri dos concursos internacionais para recrutamento de um investigador doutorado projecto financiado pela Fundação para a Ciência e a Tecnologia (PTDC/QUI-QOR/29015/2017) intitulado “BioAdhePepGel – Self-assembled minimalist peptide hydrogels inspired by mussel adhesive proteins for biomedical applications”. Universidade do Minho Centro de Química, Portugal