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Identification

Personal identification

Full name
Andreia de Sousa Fernandes

Citation names

  • Fernandes, Andreia S.

Author identifiers

Ciência ID
611E-6223-C4A9
ORCID iD
0000-0001-9803-5516

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biophysics
  • Agrarian Sciences - Agrarian and Food Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
Education
Degree Classification
2004
Concluded
 Bioquímica (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
"Rhodothermus marinus respiratory chain - Studies on Complexes I and II" (THESIS/DISSERTATION)
1999
Concluded
 Bioquímica (Biochemistry) (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Purification and Characterization of Rhodothermus marinus succinate dehydrogenase" (THESIS/DISSERTATION)
 17
Affiliation

Science

Category
Host institution 		Employer
2023/05/15 - Current Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2015/01/01 - 2023/05/14 Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2013/05/15 - 2014/12/31 Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008/05/01 - 2013/04/30 Auxiliary Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2007/10/01 - 2008/04/30 Postdoc (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2004/11/01 - 2005/03/31 Postdoc (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018/09/01 - 2019/02/28 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Viana do Castelo Escola Superior Agrária, Portugal
2005/04/01 - 2007/09/30 Invited Assistant Professor (University Teacher) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
Projects

Grant

Designation Funders
2014/03/01 - 2015/09/30 Estudos estruturais e funcionais de uma proteína de membrana, o transportador de iões KtrAB
PTDC/BBB-BEP/2017/2012
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
2012/09/30 - 2014/03/31 Allosteric modulation of EAG1 gating
info:eu-repo/grantAgreement/NIH/NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE/5R01NS081320-02/US
Integration into Research Grant Fellow
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 National Institutes of Health
Concluded
2008/04/01 - 2011 Investigating the energy transduction Q-cycle mechanism in complexes of respiratory chains
info:eu-repo/grantAgreement/FCT/3599-PPCDT/66557/PT
Post-doc
Fundação para a Ciência e a Tecnologia
2008/01/01 - 2010 Structural, bioenergetic and dynamic aspects of respiratory chain complexes studied by vibrational and spectroelectrochemical methods
info:eu-repo/grantAgreement/FCT/3599-PPCDT/64550/PT
Post-doc
Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2010 Studies on the complexes I from the respiratory chains of the thermohalophilic bacterium Rhodothermus marinus and the cyanobacterium Synechocystis sp. PCC 6803, model systems of mitochondrial and chloroplastidial complexes I
POCI/BIA-PRO/5874/2004
Post-doc
Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2026/06 - Current VEGVALOR – Valorização de Subprodutos Vegetais para Alimentos Fermentados Funcionais
COMPETE2030-FEDER-03130400
Researcher
2023/05/15 - Current BeTasty-New molecular and cell-based approaches to assess food astringency and bitterness
GA 101040462
Researcher
REQUIMTE LAQV Porto, Portugal
 European Research Council
Ongoing
2020/01/01 - 2024/12/31 Institute for Research and Innovation in Health
UIDB/04293/2020
10.54499/UIDB/04293/2020
LA/P/0070/2020
10.54499/LA/P/0070/2020
UIDP/04293/2020
10.54499/UIDP/04293/2020
UID/BIM/04293/2019
Instituto de Astrofísica e Ciências do Espaço, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto, Portugal

Instituto de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/01/01 - 2024/12/31 Associated Laboratory for Green Chemistry - Clean Technologies and Processes
UIDP/50006/2020
10.54499/UIDP/50006/2020
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade Nova de Lisboa, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Aveiro, Portugal

Universidade de Évora, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/12/01 - 2012/03/31 Synthesis and evaluation of the activity of inhibitors of fungal ABC-transporters with implications in programmed cell death
117
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Universidade do Porto
Concluded
2008/04/01 - 2011/03/31 Investigação do mecanismo de transdução de energia, ciclo-Q em complexos da cadeia respiratória
PTDC/BIA-PRO/66557/2006
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. García-Leiro, A.; Fernandes, A.S.; Castro, A.; Videira, A.; Esperanza Cerdán, M.; Isabel González-Siso, M.. "Glutathione and programmed cell death in Kluyveromyces lactis". 2013.
Conference abstract
  1. Costa, Renata; Fernandes, Andreia S.; Soares, Susana. "NEW MOLECULAR AND CELL-BASED APPROACHES TO ASSESSING FOOD ASTRINGENCY AND BITTERNESS". Paper presented in 2nd Scientific Retreat Gulbenkian New Talents Program, Lisboa, 2024.
    Published
  2. Santos, Filipa C.; Fernandes, Andreia S.; Videira, Arnaldo; Almeida, Rodrigo F.M. De. "Fungal Plasma Membrane Lipid Domains Alterations Upon Drug Exposure". Paper presented in 65th Biophysical Society Annual Meeting, 2021.
    10.1016/j.bpj.2020.11.520
  3. Zhao, Yaxian; Morais-Cabral, Joao H.; Sousa Fernandes, Andreia; Robertson, Gail A.. "An Intrinsic Ligand Mediates N- and C-Terminal Interactions with the KCNH Gating Machinery". Paper presented in 60th Biophysical Society Meeting, Los Angeles, 2016.
    10.1016/j.bpj.2015.11.1850
  4. Santos, Filipa C.; Fernandes, Andreia S.; Videira, Arnaldo; de Almeida, Rodrigo F. M.. "Biophysical characterization of Neurospora crassa membrane and its sensitivity to Staurosporine". Paper presented in EBSA 13 - 9th European Biophysics Congress, 2013.
  5. Fernandes, Andreia S.; Santos, F. C.; Videira, Arnaldo; de Almeida, R. F. M.. "Biophysical characterization of Neurospora crassa membrane and its sensitivity to staurosporine". Paper presented in 9th European Biophysics Congress EBSA 2013, 2013.
    Published
  6. Fernandes, Andreia S.; Batista, A.P.; Louro, R.O.; Teixeira, M.; Steuber, J.; Pereira, M.M.. "A role for sodium ions in the respiratory chain of Rhodothermus marinus". Paper presented in 15th European Bioenergetics Conference 2008, Dublin, 2008.
  7. Fernandes, Andreia S.; Batista, A.P.; Teixeira, M.; Pereira, M.M.. "NADH dehydrogenases from Rhodothermus marinus". Paper presented in 15th European Bioenergetics Conference 2008, Dublin, 2008.
    Published
  8. Fernandes, Andreia S.; Batista, A.P.; Pereira, M.M.; Coelho, A.; Teixeira, M.. "Subunits Identification of the Complex I from Rhodothermus marinus". Paper presented in 13th International Conference on Biological Inorganic Chemistry, Viena, 2007.
    Published
  9. Fernandes, Andreia S.; Pereira, M.M.; Teixeira, M.; Konstantinov, A.. "Quinone reduction by Rhodothermus marinus succinate:menaquinone oxidoreductase". Paper presented in 13th European Bioenergetics Conference, Pisa, 2004.
  10. Fernandes, Andreia S.; Melo, A. M.P.; Lobo, S.A.; Pereira, M.M.; Saraiva, L.M.; Teixeira, M.. "The rotenone sensitive NADH:menaquinone oxidoreductase from the respiratory chain of Rhodothermus marinus". Paper presented in 13th European Bioenergetics Conference, 2004.
  11. Fernandes, Andreia S.; Pereira, M.M.; Teixeira, M.. "The NADH:menaquinone oxidoreductase from the thermohalophilic bacterium Rhodothermus marinus". Paper presented in 12th European Bioenergetics Conference, Arcachon, 2002.
  12. Fernandes, Andreia S.; Pereira, M.M.; Teixeira, M.. "Complex I and II from the respiratory chain of the thermophilic bacterium Rhodothermus marinus". Paper presented in 10th International Conference on Bioinorganic Chemistry, Florence, 2001.
  13. Fernandes, Andreia S.; Lemos, R.S.; LeGall, J.; Xavier, A.; Pereira, M.M.; Teixeira, M.. "Succinate:menaquinone reductase from Rhodothermus marinus and fumarate reductase from Desulfovibrio gigas: Redox-Bohr effect on the low potential heme". Paper presented in Federation Biochemical Societies Meeting, Lisboa, 2001.
Journal article
  1. Susana Soares; Carlos Guerreiro; Rita Vilaça; Joana Guedes; Andreia Fernandes. "New molecular and cell-based approaches to assess food astringency and bitterness". The Project Repository Journal (2024): http://dx.doi.org/10.54050/prj2122280.
    10.54050/prj2122280
  2. Fernandes, Andreia S.; Pombinho, António; Teixeira-Duarte, Celso M.; Morais-Cabral, João H.; Harley, Carol A.. "Fluorometric Liposome Screen for Inhibitors of a Physiologically Important Bacterial Ion Channel". Frontiers in Microbiology 12 (2021): http://dx.doi.org/10.3389/fmicb.2021.603700.
    Open access • Published • 10.3389/fmicb.2021.603700
  3. Santos, Filipa C.; Lobo, Gerson M.; Fernandes, Andreia S.; Videira, Arnaldo; de Almeida, Rodrigo F. M.. "Changes in the Biophysical Properties of the Cell Membrane Are Involved in the Response of Neurospora crassa to Staurosporine". Frontiers in Physiology 9 (2018): http://dx.doi.org/10.3389/fphys.2018.01375.
    10.3389/fphys.2018.01375
  4. Santos, F.C.; Fernandes, A.S.; Antunes, C.A.C.; Moreira, F.P.; Videira, A.; Marinho, H.S.; de Almeida, R.F.M.. "Reorganization of plasma membrane lipid domains during conidial germination". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1862 2 (2017): 156-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-84997047832&partnerID=MN8TOARS.
    10.1016/j.bbalip.2016.10.011
  5. Marques-Carvalho, M.J.; Oppermann, J.; Muñoz, E.; Fernandes, A.S.; Gabant, G.; Cadene, M.; Heinemann, S.H.; Schönherr, R.; Morais-Cabral, J.H.. "Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel". Structure 24 10 (2016): 1742-1754. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989908805&partnerID=MN8TOARS.
    10.1016/j.str.2016.07.020
  6. Harley, C.A.; Starek, G.; Jones, D.K.; Fernandes, A.S.; Robertson, G.A.; Morais-Cabral, J.H.. "Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain". Proceedings of the National Academy of Sciences of the United States of America 113 35 (2016): 9916-9921. http://www.scopus.com/inward/record.url?eid=2-s2.0-84984876913&partnerID=MN8TOARS.
    10.1073/pnas.1601116113
  7. Fernandes, A.S.; Morais-Cabral, J.H.; Harley, C.A.. "Screening for Non-Pore-Binding Modulators of EAG K+Channels". Journal of Biomolecular Screening 21 7 (2016): 758-765. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979221631&partnerID=MN8TOARS.
    10.1177/1087057116636592
  8. Fernandes, A.S.; Castro, A.; Videira, A.. "Reduced glutathione export during programmed cell death of Neurospora crassa". Apoptosis 18 8 (2013): 940-948. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879596657&partnerID=MN8TOARS.
    10.1007/s10495-013-0858-y
  9. Fernandes, A.S.; Pedro Gonçalves, A.; Castro, A.; Lopes, T.A.; Gardner, R.; Louise Glass, N.; Videira, A.. "Modulation of fungal sensitivity to staurosporine by targeting proteins identified by transcriptional profiling". Fungal Genetics and Biology 48 12 (2011): 1130-1138. http://www.scopus.com/inward/record.url?eid=2-s2.0-82555176625&partnerID=MN8TOARS.
    10.1016/j.fgb.2011.09.004
  10. Castro, A.; Lemos, C.; Falcão, A.; Fernandes, A.S.; Louise Glass, N.; Videira, A.. "Rotenone enhances the antifungal properties of staurosporine". Eukaryotic Cell 9 6 (2010): 906-914. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953792885&partnerID=MN8TOARS.
    10.1128/EC.00003-10
  11. Batista, A.P.; Fernandes, A.S.; Louro, R.O.; Steuber, J.; Pereira, M.M.. "Energy conservation by Rhodothermus marinus respiratory complex I". Biochimica et Biophysica Acta - Bioenergetics 1797 4 (2010): 509-515. http://www.scopus.com/inward/record.url?eid=2-s2.0-76849090956&partnerID=MN8TOARS.
    10.1016/j.bbabio.2010.01.020
  12. Fernandes, A.S.; Sousa, F.L.; Teixeira, M.; Pereira, M.M.. "Electron paramagnetic resonance studies of the iron-sulfur centers from complex I of Rhodothermus marinus". Biochemistry 45 3 (2006): 1002-1008. http://www.scopus.com/inward/record.url?eid=2-s2.0-31044432666&partnerID=MN8TOARS.
    10.1021/bi0519452
  13. Fernandes, A.S.; Konstantinov, A.A.; Teixeira, M.; Pereira, M.M.. "Quinone reduction by Rhodothermus marinus succinate:menaquinone oxidoreductase is not stimulated by the membrane potential". Biochemical and Biophysical Research Communications 330 2 (2005): 565-570. http://www.scopus.com/inward/record.url?eid=2-s2.0-15744377171&partnerID=MN8TOARS.
    10.1016/j.bbrc.2005.03.015
  14. Melo, A.M.P.; Lobo, S.A.L.; Sousa, F.L.; Fernandes, A.S.; Pereira, M.M.; Hreggvidsson, G.O.; Kristjansson, J.K.; Saraiva, L.M.; Teixeira, M.. "A nhaD Na+/H+ antiporter and a pcd homologues are among the Rhodothermus marinus complex I genes". Biochimica et Biophysica Acta - Bioenergetics 1709 1 (2005): 95-103. http://www.scopus.com/inward/record.url?eid=2-s2.0-23244458108&partnerID=MN8TOARS.
    10.1016/j.bbabio.2005.06.003
  15. Pereira, M.M.; Bandeiras, T.M.; Fernandes, A.S.; Lemos, R.S.; Melo, A.M.P.; Teixeira, M.. "Respiratory Chains from Aerobic Thermophilic Prokaryotes". Journal of Bioenergetics and Biomembranes 36 1 (2004): 93-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-10344244184&partnerID=MN8TOARS.
    10.1023/B:JOBB.0000019601.74394.67
  16. Lemos, R.S.; Fernandes, A.S.; Pereira, M.M.; Gomes, C.M.; Teixeira, M.. "Quinol:fumarate oxidoreductases and succinate:quinone oxidoreductases: Phylogenetic relationships, metal centres and membrane attachment". Biochimica et Biophysica Acta - Bioenergetics 1553 1-2 (2002): 158-170. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037122944&partnerID=MN8TOARS.
    10.1016/S0005-2728(01)00239-0
  17. Fernandes, A.S.; Pereira, M.M.; Teixeira, M.. "Purification and characterization of the complex I from the respiratory chain of Rhodothermus marinus". Journal of Bioenergetics and Biomembranes 34 6 (2002): 413-421. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036962311&partnerID=MN8TOARS.
    10.1023/A:1022509907553
  18. Fernandes, A.S.; Pereira, M.M.; Teixeira, M.. "The succinate dehydrogenase from the thermohalophilic bacterium Rhodothermus marinus: Redox-Bohr effect on heme bL1". Journal of Bioenergetics and Biomembranes 33 4 (2001): 343-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034750861&partnerID=MN8TOARS.
    10.1023/A:1010663424846
  19. Pereira, M.M.; Santana, M.; Soares, C.M.; Mendes, J.; Carita, J.N.; Fernandes, A.S.; Saraste, M.; Carrondo, M.A.; Teixeira, M.. "The caa3 terminal oxidase of the thermohalophilic bacterium Rhodothermus marinus: A HiPIP:oxygen oxidoreductase lacking the key glutamate of the D-channel". Biochimica et Biophysica Acta - Bioenergetics 1413 1 (1999): 1-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032778747&partnerID=MN8TOARS.
    10.1016/S0005-2728(99)00073-0
Distinctions

Award

1995 "Menção Honrosa" for the classifications of first year of Licenciatura
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Other distinction

2015 Post-Doctoral Fellowsip (SFRH/BPD/105672/2015)
Fundação para a Ciência e a Tecnologia, Portugal
2006 Post-Doctoral Fellowship (SFRH/BPD/34493/2006)
Fundação para a Ciência e a Tecnologia, Portugal
2005 Fellowship for the participation on the course “Advanced Bacterial Genetics”, Cold Spring Harbor, New York, U.S.A
Fundação Luso-Americana, Portugal
2004 Post-Doctoral Fellowship ((SFRH/BPD/ 16388/2004)
Fundação para a Ciência e a Tecnologia, Portugal
2004 Short-term fellowship, to work with Prof. Julia Steuber, ETH, Zurich
Federation of the European Biochemical Societies, United Kingdom
2003 Fellowship for the participation on the “Gordon Conference in Bioenergetics”, 22th to 27th June, Meriden, New Hampshire, E.U.A.
Fundação Luso-Americana, Portugal
2000 PhD Fellowship (BD/1163/00)
Fundação para a Ciência e a Tecnologia, Portugal
1999 Fellowship for research trainee of Licenciatura in Biochemistry
Universidade de Lisboa Faculdade de Ciências, Portugal