???global.info.a_carregar???
Vera Marisa Costa (VMC) has completed her PhD in Toxicology in 2009/06/23 in the University of Porto (Faculty of Pharmacy (FFUP).) She has been a Researcher in FFUP-ICETA under Norma Transitória. Currently, she holds the position of a scientific collaborator at UCIBIO/FFUP, waiting the signing of a new contract following her success in a recent application. VMC has published +100 articles in International Journals with Peer Review, mostly in Journals of Q1 on their fields. VMC is Associate Editor on four Journals: Brazilian Journal of Pharmaceutical Sciences, since 2019, Cardiovascular Toxicology (Springer-Nature Publishing) since 2020, Frontiers in Toxicology - Clinical Toxicology since 2022, and Helyion (Elsevier) since 2023. VMC has participated in the organization of 4 scientific events, being two international. She has extensive pegagogic experience in Pharmacology and Toxicology, being Invited Assistant Professor in CESPU and and colaborating in the Graduate Program of Bioexperimentação, Universidade of Passo Fundo, Brazil and FFUP. Her works focus on Medical and Health Sciences with emphasis on Pharmacology and Toxicology, maily focusing on Onco-Cardiology, Chemobrain and Toxin Toxicity. She was the principal investigator (PI) of two FCT funded projects on cardioncology: Why is mitoxantrone a poison to the heart? Focus on mitochondria, cytoskeleton, and metabolic bioactivation mechanisms (EXPL/DTP-FTO/0290/2012) and Poisoning the heart with anticancer drugs: is metabolic bioactivation or aging promotion the link to the cardiotoxicity of anticancer drugs? (PTDC/DTPFTO/1489/2014), with participation on several others as researcher, one of them international and EU funded. She also participitated/participates in 3 COST actions, as member: CA16225 - Realising the therapeutic potential of novel cardioprotective therapies; Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases (BenBedPhar) CA20121 and CA21152 Implementation of science theory-based framework and toolkit to support cancer survivorship care. VMC has been an Evaluator of Scientific Projects of the Italian Ministry for University Research (MUR) since 2020, of the Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI) of Romania and of the Science Fund of the Republic of Serbia since 2021, being that in the latter she was also Lead Reviewer. She presently is working for the Austrian Science Fund (FWF) and has been selected as expert for the DIANA programme. She is presently the (co)supervisor of 4 PhD students. VMC has (co)supervised four PhD students (one as principal) that have successfully accomplished their works and she has (co)supervised 17 MSc dissertation(s) (plus 3 are ongoing). Regarding her research activities, she is nvolved with several fields of research with high social /social impact: i) unraveling the anticancer drugs-elicited mechanisms underlying the onset of cardiotoxicity; ii) developing improved in vitro and in vivo models to predict the early cardiotoxic events in the field of cardio-oncology; iii) disclosing the adverse outcome pathways regarding the neurotoxicity of anticancer therapies; iv) optimization of tools to identify cancer patients poor quality of life; v) development of antidotes against mushroom toxicity; vii) the pharmacological and toxicological evaluation of compounds to be used against Alzheimer and Parkinsons diseases; viii) evaluation of toxicity of drugs of abuse. VMC is also involved with extension programs, that providing evidence-based recommendations to identify and manage cancer survivors poor quality of life. In her curriculum Ciência Vitae the most frequent terms in the context of scientific outputs are: chemotherapy, cardio-oncology, toxicology; catecolamines; doxorubicin; cardiac cells; in vivo; oxidative stress; amanitin; RNA polymerase II; oncology; antidotes; hepatotoxicity; MDMA; amphetamines; cathinones; chemobrain.
Read full resume ↓
Identification

Personal identification

Full name
Vera Marisa Freitas Costa

Citation names

  • Costa, Vera
  • Costa, Vera Marisa
  • Costa, Vera M

Author identifiers

Ciência ID
601E-EFCD-E4D8
ORCID iD
0000-0002-0471-2756
Researcher Id
D-6284-2013
Scopus Author Id
17134373000

Email addresses

  • veramcosta@ff.up.pt (Professional)

Telephones

Telephone
  • 225026661 (Professional)

Addresses

  • R. Jorge de Viterbo Ferreira 228, 4050-313, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Health Sciences - Substance Abuse
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Other Medical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Advanced (C1) Proficiency (C2) Advanced (C1)
French Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1) Elementary (A2)
Spanish; Castilian Intermediate (B1) Elementary (A2) Elementary (A2) Intermediate (B1) Elementary (A2)
Education
Degree Classification
2011/05/07 - 2011/05/12
Concluded
 Creating resources and activities in Moodle (Especialização pós-licenciatura)
Instituto Universitário de Ciências da Saúde, Portugal
 Approved
2005/02/01 - 2009/06/23
Concluded
 Toxicology (Doutoramento)
Major in Role of catecholamines and reactive oxygen species in the mechanism of oxidative stress-induced heart disease: in vitro studies using freshly isolated rat cardiomyocytes
Universidade do Porto Faculdade de Farmácia, Portugal
"Oxidative Stress in Heart Disease: Role of Catecholamines and Metals. in Vitro and Clinical Studies" (THESIS/DISSERTATION)
 Unanimity
2009/05/15 - 2009/05/31
Concluded
 Laboratory Animal Sciences (Categoria C FELASA) (Pós-Graduação)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Approved
2007/05/16 - 2007/05/18
Concluded
 Course on Animal Cell Culture (Especialização pós-licenciatura)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Approved
2006/12/01 - 2007/01/31
Concluded
 Statistical analysis of data with SPSS (Curso de Especialização Tecnológica)
ANJE Associação Nacional de Jovens Empresários, Portugal
 Approved
1998/10/01 - 2004/05/31
Concluded
 Pharmaceutical Sciences (Licenciatura)
Faculty of Pharmacy University of Porto, Portugal
 16
2003/10/06 - 2003/10/11
Concluded
 Internship at the Pharmacovigilance Unit (Especialização pós-licenciatura)
Universidade do Porto Faculdade de Medicina, Portugal
 Approved
Affiliation

Science

Category
Host institution 		Employer
2018/02/09 - 2024/02/02 Contracted Researcher (Research) Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2016/09/01 - 2017/01/01 Postdoc (Research) Fundação da Ciência e Tecnologia, Portugal
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2010/07/01 - 2016/12/31 Postdoc (Research) Fundação da Ciência e Tecnologia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2023/02/28 - 2023/07/31 Invited Assistant Professor (University Teacher) Instituto das Ciências da Saúde do Norte, Portugal
Instituto das Ciências da Saúde do Norte, Portugal
2020/12/01 - 2022/07/31 Lecturer (University Teacher) Faculty of Pharmacy University of Porto, Portugal
Universidade do Porto, Portugal
2020/12/01 - 2021/07/31 Invited Assistant (University Teacher) Faculty of Medicine of University of Porto, Portugal
Departamento Ciências da Saúde Pública e Forenses, e Educação Médica, Portugal
2014/09/01 - 2018/09/01 Lecturer (University Teacher) Faculty of Pharmacy of University of Porto, Portugal
Faculty of Pharmacy of University of Porto, Portugal
2009/03/01 - 2014/07/31 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2007/09/01 - 2014/07/31 Invited Assistant Professor (University Teacher) Instituto Universitário de Ciências da Saúde, Portugal
Instituto Universitário de Ciências da Saúde, Portugal
2007/01/01 - 2010/06/30 Lecturer (University Teacher) Universidade de Trás-os-Montes e Alto Douro Escola Superior de Enfermagem de Vila Real, Portugal
Universidade de Trás-os-Montes e Alto Douro Escola Superior de Enfermagem de Vila Real, Portugal

Others

Category
Host institution 		Employer
2024/02/09 - Current Scientific Collaborator Faculty of Pharmacy University of Porto, Portugal
Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/01/01 - 2018/02/07 Invited Scientist Grant Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2005/02/01 - 2009/06/23 PhD Student Fundação da Ciência e Tecnologia, Portugal
Faculty of Pharmacy University of Porto, Portugal
2004/06/01 - 2005/01/31 Pharmacist Sto. António Pharmacy, Portugal
Sto. António Pharmacy, Portugal
Projects

Contract

Designation Funders
2023/02/24 - Current COST CA21152- Implementation Network Europe for Cancer Survivorship Care (INE-CSC)
CA21152
Researcher
European Cooperation in Science and Technology, Belgium
2023/01/01 - Current DynaPro: Probing Dynamic Chirality to the Rescue of Melanostatin in Parkinson's Therapy
2022.01175.PTDC
Researcher
REQUIMTE LAQV Porto, Portugal
 Fundação da Ciência e Tecnologia
Ongoing
2021/11/15 - Current COST CA20121 - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases
COST CA20121
Researcher
European Cooperation in Science and Technology, Belgium
Ongoing
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDP/04378/2020
10.54499/UIDP/04378/2020
Researcher
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/09/01 - 2023/08/31 Open access Educational Materials On Naturally Occurring Molecules - sources, biological activity and use - ERASMUS+
2020-1-CZ01-KA203-078218
Researcher
Univerzita Karlova Farmaceutická Fakulta v Hradci Králové, Czech Republic
 European Comission Erasmus +
Ongoing
2022/01/01 - 2023/06/30 Methylphenidate and amphetamine-induced synaptogenesis and neurite outgrowth in attention deficit hyperactivity disorder (ADHD)
EXPL/MED-FAR/0203/2021
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/08/02 - 2022/04/18 COST CA16225 - COST Action Realising the therapeutic potential of novel cardioprotective therapies
COST CA16225
Researcher
European Cooperation in Science and Technology, Belgium
 European Cooperation in Science and Technology Action Disaster Bioethics
Concluded
2021/09/21 - 2022/02/28 SCRAtis - 2-Estirilcromonas no tratamento da artrite reumatoide: possível alternativa terapêutica?
PTDC/MED-QUI/29253/2017
Researcher
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
2019/01/01 - 2019/12/31 Unidade de Ciências Biomoleculares Aplicadas
UID/Multi/04378/2019
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/07/11 - 2019/12/31 Poisoning the heart with anticancer drugs: is metabolic bioactivation or aging promotion the link to the cardiotoxicity of anticancer drugs?
PTDC/DTP-FTO/1489/2014
PTDC/DTPFTO/ 1489/2014
Principal investigator
Universidade de Aveiro, Portugal

Universidade do Porto Faculdade de Desporto, Portugal
Fundação para a Ciência e a Tecnologia

Fundação da Ciência e Tecnologia
Concluded
2016/06/01 - 2019/07/31 DESignBIOtecHealth - New Technologies for three Health Challenges of Modern Societies: Diabetes, Drug Abuse and Kidney Diseases
NORTE-01-0145-FEDER-000024
Researcher
European Regional Development Fund
Concluded
2016/05/01 - 2016/11/30 Development of antidotes for Amanita phalloides intoxications, from in silico to the intoxicated patient
PTDC-DTP-FTO-4973-2014 – POCI-01-0145-FEDER 016545
Researcher
Fundação da Ciência e Tecnologia
Concluded
2013/05/02 - 2014/10/31 WHY IS MITOXANTRONE A POISON TO THE HEART? FOCUSSING ON THE MITOCHONDRIA, CYTOSKELETON, AND METABOLIC BIOACTIVATION MECHANISMS
EXPL/DTP-FTO/0290/2012
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/05/01 - 2014/10/31 Why is mitoxantrone a poison to the heart? Focus on mitochondria, cytoskeleton, and metabolic bioactivation mechanisms.
EXPL/DTP-FTO/0290/2012
Principal investigator
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Faculdade de Desporto, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/03/01 - 2013/11/30 IMPLICATIONS OF AMPHETAMINE PSYCHOSTIMULANTS ABUSE IN BRAIN AGING
PTDC/SAU-FCF/102958/2008
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Coimbra, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/06/01 - 2013/06/30 A role for Nrf2/ARE cytoprotective signalling in iron overload. Adaptive response to oxidative stress as a disease modifier in HFE-associated hereditary hemochromatosis.
PTDC/SAU-FCF/101177/2008
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 6 - 2011-2012
PEst-C/EQB/LA0006/2011
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/01 - 2009/09 OXIDATIVE STRESS IN HEART DISEASE: ROLE OF CATECHOLAMINES
Provided by PTCRIS: 82340
82340
PhD Student Fellow
Faculty of Pharmacy of University of Porto, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2005/10/01 - 2007/12/31 Stress oxidativo na Doença Cardíaca: acção das catecolaminas
POCI/SAU-OBS/55849/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

REQUIMTE LAQV Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade do Porto, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015 - 2021 UnIdade Ciências Biomoleculares Aplicadas
4378
Researcher
Fundação da Ciência e Tecnologia
Outputs

Publications

Book chapter
  1. Costa, Vera M; Carvalho, Félix; Seabra, Vítor. "Metais e Metalóides". In Toxicologia Alimentar, edited by Oliveira, Nuno G.; Carvalho, Félix; Dinis, Ricardo. Portugal: Lidel, 2023.
    Submitted
  2. Costa, Vera M; Carvalho, Ana Rita; Capela, João Paulo; Carvalho, Félix. Corresponding author: Costa, Vera M. "Chemobrain". In Toxicological Risk Assessment and Multi-System Health Impacts from Exposure, edited by Aristides Tsatsakis, 62-72. Netherlands: Elsevier Editions, 2021.
    Published
  3. Costa, Vera M; Remião, Fernando; Carvalho, Félix Dias; Dinis-Oliveira, Ricardo Jorge; Bastos, Maria Bastos. "O coração como órgão alvo da toxicidade de xenobióticos". In Toxicologia Fundamental. 2018.
  4. Costa, Vera M; Seabra, Vítor. "Metais com Interesse Forense". In Toxicologia Forense, edited by Carvalho, Félix Dias; Bastos, Maria de Lourdes; REQUIMTE - Laboratório de Toxologia, Departamento de Ciências Biológicas, Faculdade de Farmáci; Dinis-Oliveira, Ricardo Jorge. Portugal: Edições Lidel/Pactor, 2015.
  5. Costa, Vera M; Carvalho, Félix Dias; Bastos, Maria De Lourdes; Carvalho, Rui Albuquerque; Carvalho, Marcia; Remião, Fernando. "Adrenaline and noradrenaline: partners and actors in the same play. Adrenaline and Noradrenaline: Partners and Actors in the Same Play". In Neuroscience - Dealing With Frontiers, edited by Contreras, Carlos. InTech, 2012.
Conference abstract
  1. Brandão, Sofia; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria João; Bastos, Maria de Lourdes; Carvalho, Félix; Ferreira, Rita; Costa, Vera Marisa. "The influence of the anticancer drugs doxorubicin and mitoxantrone on cardiac metabolism and autophagy". Paper presented in 56th Congress of the European Societies of Toxicology (EUROTOX 2021), 2021.
    https://doi.org/10.1016/S0378-4274(21)00556-7
  2. Sofia R, Brandão; Reis-Mendes, Ana; Carvalho, Félix; Bastos, Maria de Lourdes; Ferreira, Rita; Costa, Vera Marisa. "Effects of doxorubicin and mitoxantrone on mice cardiac mitochondrial proteome". Paper presented in 50th Meeting of the Portuguese Society of Pharmacology, 38th Meeting of Clinical Pharmacology and 19th Meeting of Toxicology (SPF 2020), Coimbra, 2020.
    Published
  3. Dionísio, Flávio; Araújo, Ana Margarida; Duarte-Araújo, Margarida; Guedes de Pinho, Paula; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa. "Cyclophosphamide main bioactivation products cause disturbance in the metabolome of AC16 cardiac cells at clinically relevant concentrations". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    Published
  4. Feio-Azevedo, R.; Costa, Vera Marisa; Gomes, Ana; Pita, Inês; Sequeira, A; Pereira, Frederico; Duarte-Araújo, M.; et al. "Aged rats are more prone to ecstasy neurotoxicity than adolescent rats". Paper presented in 50th Congress of the European Societies of Toxicology (EUROTOX), Edimburgo, 2014.
    Published
  5. Remiao, Fernando; Rossato, Luciana Grazziotin; Dallegrave, Eliane; Arbo, Marcelo; Silva, Renata; Ferreira, Rita; Amado, Francisco; et al. "Mitochondrial impairment after mitoxantrone multi-administration to male Wistar rats". 2013.
    10.1016/j.toxlet.2013.05.373
  6. Grazziotin Rossato, L.; Marisa Costa, V.; Guedes De Pinho, P.; Silva, R.; Carvalho, F.; Carmo, H.; Bastos, M.D.L.; et al. "Development of a GC/IP-MS method for simultaneous quantification of para and meta-synephrine in Caco-2 cells". Paper presented in 2010 IUTOX International Congress of Toxicology, Barcelona, 2010.
    10.1016/j.toxlet.2010.03.926
Conference paper
  1. Vitorino-Oliveira, Cláudia; Kahremany, Shirin; Nissim, Laura; Duarte-Araújo, Margarida; Carvalho, Félix; Gruzman, Arie; Costa, Vera Marisa. "The cytotoxicity of doxorubicin, sunitinib and bortezomib in AC16 cardiac cells and possible therapeutic options involving redox pathways". Paper presented in SPF 2021 - 54th Meeting of Portuguese Society of Pharmacology, 42nd Meeting of the Clinical Pharmacology and 23rd Meeting of the Toxixology, Lisboa, 2024.
  2. Vitorino-Oliveira, Cláudia; Duarte-Araújo, Margarida; Carvalho, Félix; Costa, Vera Marisa. Corresponding author: Costa, Vera Marisa. "The effect of the glutathione pathway on the cytotoxicity of sunitinib, doxorubicin and bortezomib in AC16 cells". Paper presented in XVII Meeting of Young Researchers of University of Porto, Porto, 2023.
    Published
  3. Brandão, Sofia; Filipa Reis-Mendes, Ana; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Cardiac mitochondrial dynamics, autophagy and regeneration are stirred by doxorubicin in old CD-1 mice". Paper presented in II TOX-RUN 2023, Porto, 2023.
    Published
  4. Vitorino-Oliveira, Claúdia; Kahremany, S; Nisim, L; Duarte-Araújo, M.; Carvalho, Félix; Gruzman, Arie; Costa, Vera M. "The influence of glutathione pathway modulators on the cytotoxicity of sunitinib, doxorubicin and bortezomib in AC16 cardiac cells". Paper presented in II TOX-RUN 2023, Porto, 2023.
    Published
  5. Carvalho, Ana; Ferreira, Mariana; Filipa Reis-Mendes, Ana; Ferreira, Rita; Bastos, Maria De Lourdes; Fernandes, Eduarda; Sá, Susana I; Sá SI; et al. "Unveiling the neurotoxicity of mitoxantrone: oxidative stress, apoptosis, and autophagy in the brain of adult CD-1 mice". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
    Published
  6. Costa, Vera M. "In the Heart of Cardio-Oncology: The Targets and Biomarkers of Cardiotoxicity in Anticancer Drugs". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
    Published • 10.3390/ecmc2022-13157
  7. Costa-Almeida, Hugo F.; Sampaio-Dias, Ivo E.; Sara C. Silva-Reis; Correia, XC; Costa, Vera M; Carvalho, Felix; Garía-Mera, X; Rodríguez-Borges, JE. "Synthesis, Pharmacological, and Toxicological Evaluation of Potent Melanostatin Peptidomimetics Incorporating Chiral ß-Amino Acids as Proline Surrogates". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, Online, 2022.
    Published
  8. Ferreira, Mariana; Carvalho, Félix; Costa, Vera M; Capela, João Paulo. "Evaluating the potential of methylphenidate and amphetamine acute exposure to promote neurite outgrowth and synaptogenesis in differentiated SH-SY5Y neuronal cells". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, Online, 2022.
    Published
  9. Brandão, Sofia; Reis-Mendes, A.; Duarte-Araujo, M.; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Mitoxantrone disrupts cardiac metabolism along with proteolysis and regeneration in aged mice". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, Online, 2022.
    Published
  10. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Almeida, Hugo; Costa, Vera M; García-Mera, Xerardo; Rodríguez-Borges, JA. "Chemical Strategy to Improve Bioavailability of Glypromate Peptide-Conjugates". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, Online, 2022.
    Published
  11. Carvalho, Ana; Ferreira, Mariana; Reis-Mendes, Ana; Ferreira, Rita; Fernandes, Eduarda; Sá, Susana I; Capela, João Paulo; Carvalho, Félix; Costa, Vera M. "Mitoxantrone-induced neurotoxicity in CD-1 mice.". Paper presented in I TOXRUN, Porto, 2022.
    Published
  12. Brandão, Sofia Reis; Filipa Reis-Mendes, Ana; Duarte-Araujo, M.; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Molecular alterations underlying Doxorubicin’s Chronic Cardiotoxicity in a mouse model". Paper presented in I TOXRUN, Porto, 2022.
    Published
  13. Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera; Duarte, José Alberto; Dinis-Oliveira, Ricardo; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix. "A translational in vitro and in vivo metabolomics study reveals altered hepatic metabolic pathways after acute exposure to 3,4-methylenedioxypyrovalerone". 2021.
  14. Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; et al. "Early pathways of toxicity triggered by 3,4-methylenedioxypyrovalerone unveiled by in vivo toxicometabolomics". Paper presented in EUROTOX, 2021.
    10.1016/S0378-4274(21)00553-1
  15. Carvalho, Ana Rita; Reis-Mendes, A.; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Sá, Susana I; Capela, João Paulo; Costa, Vera M. "Mitoxantrone impairs Bax and phosphorylated Tau expression on the brain of adult mice: an in vivo ‘chemobrain’ study on clinically relevant doses.". Paper presented in 15th YES Meeting Porto 2020, Porto, 2020.
    Published • 10.1097/j.pbj.0000000000000100
  16. Reis-Mendes, Ana; Duarte-Araújo, Margarida; Duarte, José Alberto; Gonçalves-Monteiro, Salomé; Remião, Fernando; Carvalho, Félix; Sousa, Emília; Bastos, Maria Lourdes; Costa, Vera Marisa. "Anticancer drugs-induced toxicity in different age male CD-1 mice". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06365
  17. Dias-Carvalho, Ana; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Bastos, Maria Lourdes; Sá, Susana I.; Capela, João Paulo; Costa, Vera Marisa. "Effects of Doxorubicin and Mitoxantrone in the brain of differently aged mice: in vivo chemobrain study". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06364
  18. Brandão, Sofia; Reis-Mendes, Ana; Carvalho, Félix; Bastos, Maria; Ferreira, Rita; Costa, Vera. "Disclosing the effect of doxorubicin and mitoxantrone on cardiac mitochondrial proteome: an in vivo approach using a murine model". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06350
  19. Malheiro, Rui Filipe; Costa, Vera Marisa; Bastos, Maria de Lourdes; Carvalho, Félix. "In vitro toxicity of alpha-amanitin in human kidney cells and evaluation of protective effect of polymyxin B". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06360
  20. Dionísio, Flávio; Araújo, Ana Margarida; Araújo, Margarida Duarte; de Pinho, Paula Guedes; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa. "The main products of cyclophosphamide bioactivation exert a cardiotoxic effect at clinical important concentrations in AC16 cardiac cells". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06366
  21. Carvalho, Ana Rita; Reis-Mendes, A.; Duarte-Araújo, M.; Guedes, Rita; Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "In vivo chemobrain study: the effects of doxorubicin and mitoxantrone in the brain of differently aged mice.". Paper presented in 14th YES Meeting, Porto, 2019.
    Published
  22. Soares, Jorge; Costa, Vera M; Bronze, Silvia; Gaspar, Helena; Santos, Susana; Bastos, Maria De Lourdes; Carvalho, Felix; Capela, João Paulo. "Mitochondrial impairment and oxidative stress play an important role in the toxicity of synthetic cathinones to dopaminergic SH-SY5Y cells". Paper presented in 55th Annual Meeting of the Society of the European Toxicology Society - EUROTOX 2019, Helsinki, 2019.
  23. Rodrigues, Daniela; Costa, Vera M; Bastos, Maria Lourdes; Carvalho, Félix. "Effects of alpha-amanitin in HepG2 cells are not prevented by drugs used in Amanita phalloides intoxications". Paper presented in 55th Annual Meeting of the Society of the European Toxicology Society - EUROTOX 2019, 2019.
    10.1016/j.toxlet.2019.09.002
  24. Dionísio, Flávio; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera M. "Cyclophosphamide metabolites 4-hydroxycyclophosphamide and acrolein exert strenuous cardiotoxicity in AC16 human cardiomyocytes, at clinical relevant concentrations". Paper presented in EUROTOX 2019 - 55th Annual Meeting of the Society of the European Toxicology Society, 2019.
    Published
  25. Brandão, Sofia; Ana Reis-Mendes; Bastos, Maria Bastos; Carvalho, Félix Dias; Ferreira, Rita; Costa, Vera M; Brandão, Sofia; et al. "Exploring the effect of anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial plasticity using a proteomic approach". Paper presented in 55th Annual Meeting of the Society of the European Toxicology Society - EUROTOX 2019, Helsinki, 2019.
  26. Dias-Carvalho, Ana; Filipa Reis-Mendes, Ana; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix Dias; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "Doxorubicin and mitoxantrone effects on the brain of differently aged mice: an in vivo chemobrain study". Paper presented in 55th Congress of European Societies of Toxicology, (Eurotox 2019) Helsinki, Finland, Helsinki, 2019.
    Published
  27. Reis-Mendes, Ana; Duarte-Araujo, Margarida; Duarte, Jose Alberto; Goncalves-Monteiro, Salome; Carvalho, Felix; Bastos, Maria Lourdes; Sousa, Emilia; Costa, Vera Marisa. "Evaluation of the toxicity induced by doxorubicin in different age male CD-1 mice". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation "The Clocks of Metabolism and Disease", Coimbra, Portugal, Coimbra, 2019.
  28. Reis-Mendes, Ana; Duarte-Araujo, Margarida; Duarte, Jose Alberto; Goncalves-Monteiro, Salome; Carvalho, Felix; Bastos, Maria Lourdes; Sousa, Emilia; Costa, Vera Marisa. "Mitoxantrone-induced toxicity in different age male CD-1 mice". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation "The Clocks of Metabolism and Disease", Coimbra, Portugal, Coimbra, 2019.
  29. Dionísio, Flávio; Duarte-Araujo, Margarida; Bastos, Maria de Lourdes; REQUIMTE - Laboratório de Toxologia, Departamento de Ciências Biológicas, Faculdade de Farmáci; Carvalho, Félix Dias; Costa, Vera M. "The main metabolites of cyclophosphamide, 4-hydroxycyclophosphamide and acrolein, are cardiotoxic at relevant clinical concentrations.". Paper presented in 14th YES Meeting Porto, Porto, 2019.
    Published • 10.1097/j.pbj.0000000000000054
  30. Remião, Fernando; Carmo, Helena; Gomes, AM; Silva, Renata; Costa, Vera M; Carvalho, Félix; Bastos, Maria De Lourdes. "Video lecture capture (VLC) - impacto na aprendizagem dos estudantes". Paper presented in Congr. Nac. Práticas Pedagógicas no Ensino Superior, 2019.
    Published
  31. Reis-Mendes, A.; Carvalho, F.; Sousa, E.; Remião, F.; Bastos, M.D.L.; Costa, V.M.. "Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Metabolotes in H9c2 Cardiac Differentiated Cells". Paper presented in 54th Congress of European Societies of Toxicology, (Eurotox 2018) Brussels, Belgium, Brussels, 2018.
    10.1016/j.toxlet.2018.07.029
  32. Carvalho, Ana Rita; Ana Reis-Mendes; Duarte-Araujo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria De Lourdes; Capela, João Paulo; Costa, Vera M. "Differential effects of doxorubicin and mitoxantrone in brain glutathione levels of different aged mice". Porto, 2018.
    Published
  33. Remião, Fernando; Rocha-pereira, Carolina; Costa, Vera M; Silva, Renata; Soares, Jorge; Casanova, Alfredo G; Carmo, Helena. "TOX-OER MOOC: uma ferramenta para o ensino e a aprendizagem". Paper presented in CNaPPES 2018 - Congr. Nac. Práticas Pedagógicas no Ensino Superior, 2018.
    Published
  34. Hrynchak, Ivanna; Sousa, Emília; de Lourdes Bastos, Maria; Pinto, Madalena; Costa, Vera Marisa. "Studies towards the synthesis of dicarboxylic acid metabolite of mitoxantrone". Paper presented in 12nd International YES Meeting, Porto, Portugal, Porto, 2017.
    10.1016/j.pbj.2017.07.107
  35. Araújo, Silvana da Costa; Costa, Vera M; Pereira, Frederico; Fernandes, Eduarda; Bastos, Maria De Lourdes; Carvalho, Félix; Capela, João Paulo. "‘Ecstasy’ and amphetamine neurotoxicity to cultured rat cortical neurons in a continuous exposure model". Paper presented in EUROTOX 2013 - 49th Congress of the European Societies of Toxicology, Interlaken, 2013.
    Published
  36. Costa, Vera M; Capela, João Paulo; Bastos, Maria De Lourdes; Duarte, Jose Alberto; Remião, Fernando; Carvalho, Félix. "Pharmacological concentrations of mitoxantrone are able to transiently activate caspases and dually modify glutathione pathways in HL-1 cells.". Paper presented in EUROTOX 2013 - 49th Congress of the European Societies of Toxicology, Interlaken, 2013.
    Published
  37. Araújo, Silvana da Costa; Costa, Vera M; Pereira, Frederico; Fernandes, Eduarda; Bastos, Maria De Lourdes; Carvalho, Félix; Capela, João Paulo. "‘Ecstasy’ and amphetamine neurotoxicity to cultured rat cortical neurons in a continuous exposure model". Paper presented in 6th European Congress on Pharmacology EPHAR 2012, Granada, 2012.
    Published
  38. Costa, Vera M; Capela, João Paulo; Bastos, Maria De Lourdes; Duarte, Jose Alberto; Remião, Fernando; Carvalho, Félix. "Pharmacological concentrations of mitoxantrone are able to activate caspases and dually modify glutathione pathways in HL-1 cardiomyocytes.". Paper presented in 6th European Congress on Pharmacology EPHAR 2012, Granada, 2012.
    Published
  39. Rossato, Luciana Grazziotin; Costa, Vera M; Dallegrave, Eliane; Bastos, Maria De Lourdes; Dinis-Oliveira, Ricardo Jorge; Duarte, José A.; Palmeira, Carlos; Remião, Fernando. "Mitoxantrone: A comparative study of early and late toxic effects in rats". Paper presented in 2012 EUROTOX 48th Congress of the European Societies of Toxicology, Stockholm, 2012.
    Published
  40. Araújo, Silvana da Costa; Costa, Vera M; Pereira, Frederico C; Fernandes, Eduarda; Bastos, Maria De Lourdes; Carvalho, Félix; Capela, João Paulo. "‘Ecstasy’ and amphetamine induce developmental neurotoxicity to immature cultured rat cortical neurons". Paper presented in EUROTOX 2011 - 47th Congress of the European Societies of Toxicology, Paris, 2011.
    Published
  41. Araújo, Silvana da Costa; Costa, Vera M; Ruscher, Karsten; Bastos, Maria De Lourdes; Dirnagl, Ulrich; Meisel, Andreas; Carvalho, Félix; Capela, João Paulo. "Hallucinogenic amphetamines neurotoxicity in cultured hippocampal neurons.". Paper presented in EUROTOX 2011 - 47th Congress of the European Societies of Toxicology, Paris, 2011.
    Published
  42. Costa, Vera M; Capela, João Paulo; Bastos, Maria De Lourdes; Remião, Fernando; Duarte, Jose Alberto; Carvalho, Félix. "N-acetyl-cysteine prevents the cytotoxicity of adrenaline oxidation in SH-SY5Y cells". Paper presented in EUROTOX 2011 - 47th Congress of the European Societies of Toxicology, Paris, 2011.
    Published
  43. Rossato, Luciana G.; Costa, Vera M; Firmo, Eduarda; Bastos, Maria Bastos; Palmeira, Carlos; Remião, Fernando. "Therapeutic concentrations of mitoxantrone elicit cytotoxic effects on H9c2 cells". Paper presented in EUROTOX 2011 - 47th Congress of the European Societies of Toxicology, Paris, 2011.
    Published
  44. Duarte, Tiago; Bento, A; Picarote, G; Costa, Vera M; Carvalho, Félix. "Understanding the role of NRF2/ARE signalling in the cellular defence against iron toxicity". Paper presented in International BioIron Society Biennial World Meeting (IBIS 2011 - Vancouver), Vancouver, 2011.
    Published
  45. Rossato, Luciana Grazziotin; Costa, Vera M; de Pinho, Paula Guedes; Carvalho, Félix; Carmo, Helena; Bastos, Maria De Lourdes; Remião, Fernando. "Role of organic cation mediated transport and oxidative stress in the synephrine induced-toxicity in freshly isolated cardiomyocytes. Toxicol Lett 196S: S142.". Paper presented in 2010 IUTOX International Congress of Toxicology, Barcelona, 2010.
    Published
  46. Rossato, Luciana Grazziotin; Costa, Vera M; de Pinho, Paula Guedes; Silva, Renata; Carvalho, Félix; Carmo, Helena; Bastos, Maria de Lourdes; Remião, Fernando. "Development of a GC/IT-MS method for simultaneous quantification of para and meta-synephrine in Caco-2 cells". Paper presented in 2010 IUTOX International Congress of Toxicology, Barcelona, 2010.
    Published
  47. Costa, Vera Marisa; Carvalho, Felix; de Lourdes Bastos, Maria; Carvalho, Rui; Carvalho, Márcia; Remião, Fernando. "Time dependent activation of transcription factors in freshly isolated cardiomyocytes: Adrenaline and reactive oxygen species incubation". Paper presented in Abstracts of the 44th Congress of the European Societies of Toxicology (EUROTOX 2007), 2009.
    10.1016/j.toxlet.2007.05.036
  48. Costa, Vera M; Silva, Renata; Tavares, Ludgero Canario; Vitorino, Rui; Amado, Francisco; Carvalho, Félix; Bastos, Maria De Lourdes; et al. "Adrenaline and reactive oxygen species, elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes". Paper presented in EUROTOX 2009 - 46th Congress of the European Societies of Toxicology, Dresden, 2009.
    Published
  49. Rossato, Luciana Grazziotin; Carmo, Helena; Carvalho, Félix; de Lourdes Bastos, Maria; Costa, Vera Marisa; Remião, Fernando. "meta-Synephrine induces oxidative stress in freshly isolated cardiomyocytes". Paper presented in 46th Congress of the European Societies of Toxicology (EUROTOX 2009), Dresden, 2009.
    10.1016/j.toxlet.2009.06.428
  50. Oliveira, Susana; Almeida, SF ; Picarote, Gonçalo; Costa, Vera M; Carvalho, Félix; Azevedo, JE; Pinto, Jorge P; Sousa, Maria. "Activation of an unfolded protein response modulates the expression of iron-related genes". Paper presented in 2009 International BioIron Society Meeting, Porto, 2009.
    Published
  51. Costa, Vera M.; Ferreira, Luísa M.; Branco, Paula S.; Carvalho, Félix; Bastos, Maria L.; Carvalho, Rui A.; Carvalho, Márcia; Remião, Fernando. "Characterization of adrenaline and adrenaline-GSH adduct transport in freshly isolated rat cardiomyocytes". Paper presented in 45th Congress of European Societies of Toxicology, (Eurotox 2008), Rhodes, 2008.
    10.1016/j.toxlet.2008.06.405
  52. Costa, Vera; Silva, Renata; Ferreira, Luísa; Branco, Paula; Carvalho, Félix; Bastos, Maria Lourdes; Carvalho, Rui; Carvalho, Márcia; Remião, Fernando. "Oxidation process of adrenaline in freshly isolated rat cardiomyocytes: Formation of adrenochrome, quinoproteins and Gsh-adduct". Paper presented in 44th Congress of the European Societies of Toxicology (EUROTOX 2007), Amsterdam, 2007.
    10.1016/j.toxlet.2007.05.189
  53. Silva, Renata; Costa, Vera Marisa; Boldt, Silvia; Carmo, Helena; Carvalho, Félix; Bastos, Maria Lourdes. "Validation of a HPLC-ECD method for the detection of adrenaline-GSH adducts in biological samples". Paper presented in EUROTOX 2006/6 CTDC Congress, Cravtat, Croatia, Catvat, 2006.
    10.1016/J.TOXLET.2006.06.277
  54. Costa, Vera M; Carvalho, Márcia; Carvalho, Félix; Bastos, Maria De Lourdes; Carvalho, Rui; Remião, Fernando. "Effect of catecholamine and free radicals on calcium tolerant cardiomyocytes: adduct formation". Paper presented in 43rd Congress of the European Societies of Toxicology and the 6th Congress of Toxicology in Developing Countries, Cavtat, Croatia, Cavtat, 2006.
    Published
  55. Silva, Renata; Costa, V.; Boldt, Silvia; Carmo, H.; Carvalho, Félix; Carvalho, Márcia; Carvalho, Rui Albuquerque; Bastos, M. Lourdes; Remião, Fernando. "Detection of GSH adducts of catechoamines in biological samples". Paper presented in 42nd Congress of the European Societies of Toxicology (EUROTOX 2005), Cracow, 2005.
Conference poster
  1. Luís, Cláudia; Vitorino-Oliveira, Cláudia; Gaspar, Helena; Carvalho, Félix; Capela, João Paulo; Costa, Vera Marisa. Corresponding author: Luís, Cláudia. "Synthetic Cathinones vs Methamphetamine: A Comparative In Vitro Cytotoxicity Study on Cardiac AC16 Cells". Paper presented in IX Edição das Jornadas da Bioquímica do NEBQUP, 2024.
  2. Dias-Carvalho, Ana; Araújo, Ana Margarida; Reis-Mendes, A.; Sequeira, CO; Pereira, AS; Guedes de Pinho, Paula; Carvalho, Félix; et al. "Chemobrain: exploring the impact of a clinically relevant dose of mitoxantrone in the metabolic profile of CD-1 mice brain". Paper presented in EMBO Young Scientists¿ Forum (Lisbon), 2023.
  3. Vitorino-Oliveira, Cláudia; Kahremany, Shirin; Nissim, Laura; Duarte-Araújo, Margarida; Carvalho, Félix; Gruzman, Arie; Costa, Vera Marisa. Corresponding author: Vitorino-Oliveira, Cláudia. "A citotoxicidade do sunitinib, da doxorrubicina e do bortezomib nas células AC16 e possíveis terapias envolvendo as vias redox". Paper presented in 5º Encontro Nacional de Jovens Investigadores em Oncologia, 2023.
  4. Vitorino-Oliveira, Cláudia; Kahremany, Shirin; Nissim, Laura; Duarte-Araújo, Margarida; Carvalho, Félix; Gruzman, Arie; Costa, Vera Marisa. Corresponding author: Vitorino-Oliveira, Cláudia. "The cytotoxicity of sunitinib, doxorubicin and bortezomib in AC16 cardiac cells and possible therapeutic oprtions involving redox pathways". Paper presented in 18th YES Meeting, 2023.
  5. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Correia da Silva, Daniela; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Costa, Vera M; et al. Corresponding author: Sara C. Silva-Reis. "Exploring the biological impact of proline residue on Glypromate bioconjugates". Paper presented in MedChem 2023, 2023.
  6. Ivo E. Sampaio-Dias; Maronde, DAIANE; Sara C. Silva-Reis; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Costa, Vera M; García-Mera, Xerardo; J. E. Rodriguez-Borges. Corresponding author: Ivo E. Sampaio-Dias. "Exploring the Lipophilic Bullet Approach in Melanostatin Neuropeptide". Paper presented in IX SEQT Symposium of Medicinal Chemistry Young Researchers, 2023.
  7. Adelaide Sousa; Rui Azevedo; Costa, Vera M; Sara Oliveira; Inês Preguiça; Sofia Viana; Flávio Reis; et al. "Impact of dietary exposure to silver nanoparticles on the intestinal inflammatory response in C57BL/6J mice". Paper presented in 12th International Symposium on Biological Monitoring in Occupational and Environmental Health, 2023.
  8. Sofia R, Brandão; Oliveira, Paula; Carvalho, Félix; Ferreira, Rita; Costa, Vera Marisa. "Doxorubicin induced mitochondrial adaptation on female Wistar rats with mammary carcinogenesis". Paper presented in MitoPorto 2023 - Mitochondrial physiology, redox biology, and genetics, 2023.
  9. Vitorino-Oliveira, Cláudia; Kahremany, Shirin; Nissim, Laura; Duarte-Araújo, Margarida; Carvalho, Félix; Costa, Vera Marisa. Corresponding author: Costa, Vera Marisa. "The influence of oxidative stress modulators on the cytotoxicity of sunitinib, doxorubicin and bortezomib in AC16 cardiac cells". Paper presented in VIII Jornadas da Bioquímica, 2023.
  10. Beatriz L. Pires-Lima; Sara C. Silva-Reis; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Costa, Vera M; García-Mera, Xerardo; J. E. Rodriguez-Borges; Ivo E. Sampaio-Dias. "Using Proline Bioisosteres for the Assembly of Potent Melanostatin (MIF-1) Analogues". Paper presented in ENEQUI - Encontro Nacional de Estudantes de Química, 2023.
  11. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; da Silva, Daniela Correia; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Costa, Vera Marisa; et al. "Discovery of Glypromate Conjugates with Biomedical Applications in Alzheimeir's Disease". Paper presented in 2nd Symposium on Alzheimer's Disease, 2023.
  12. Ivo E. Sampaio-Dias; Sara C. Silva-Reis; Reis-Mendes, Ana; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Costa, Vera M; García-Mera, Xerardo; J. E. Rodriguez-Borges. Corresponding author: Ivo E. Sampaio-Dias. "Application of 2-azanorbornane for the assembly of bioactive peptidomimetics". Paper presented in MedChem 2023, 2023.
  13. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Costa, Vera M; Correia da Silva, Daniela; Pereira, David M.; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; et al. Corresponding author: Sara C. Silva-Reis. "Unraveling the role of Proline on the Biological activity of Glypromate Bioconjugates". Paper presented in IX Symposium of Medicinal Chemistry Young Researchers, 2023.
  14. Beatriz L. Pires-Lima; Sara C. Silva-Reis; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Costa, Vera M; García-Mera, Xerardo; J. E. Rodriguez-Borges. Corresponding author: Beatriz L. Pires-Lima. "Pyridine-Based Melanostatin Bioisoteres As Positive Allosteric Modulators Of The Dopamine D2 Receptors". Paper presented in IX Symposium of Medicinal Chemistry Young Researchers, 2023.
  15. Costa-Almeida, Hugo F.; Sara C. Silva-Reis; Correia, Xavier Cruz; Beatriz L. Pires-Lima; Costa, Vera M; García-Mera, Xerardo; J. E. Rodriguez-Borges; Ivo E. Sampaio-Dias. Corresponding author: Costa-Almeida, Hugo F.. "Exploring The Impact Of Proline Puckering On The Modulatory Activity Of Melanostatin Neuropeptide". Paper presented in IX Symposium of Medicinal Chemistry Young Researchers, 2023.
  16. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Costa, Vera Marisa; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; García-Mera, Xerardo; José Enrique Rodriguez Borges. Corresponding author: Sara C. Silva-Reis. "Design, Synthesis, and Biological Evaluation of Glypromate-Based Neuroprotective Conjugates with Pharmaceutical Active Ingredients". Paper presented in Congreso Internacional: XXVI Encontro Galego-Portugués de Química, 2022.
  17. Brandão, Sofia Reis; Filipa Reis-Mendes, Ana; Duarte-Araújo, M.; Rocha, Hugo; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Cardiac metabolic adaptation after doxorubicin and mitoxantrone on adult mice". Paper presented in 1st Conference of the Doctoral Program Metabolism – Clinical and Experimental, The prism of Diabesity: looking by a different perspective, 2022.
  18. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Costa, Vera Marisa; Correia, Xavier Cruz; Hugo F. Costa-Almeida; García-Mera, Xerardo; José Enrique Rodriguez Borges. "Peptide-amine Conjugates targeting Neurodegenerative Diseases". Paper presented in XX National Meeting of the Spanish Society of Medicinal Chemistry (SEQT), 2022.
  19. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Costa, Vera Marisa; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; García-Mera, Xerardo; José Enrique Rodriguez Borges. "Application of Hybrid Glypromate® Conjugates in Neurodegenerative Diseases". Paper presented in Encontro Ciência 2022, 2022.
  20. Moreira-Pais, Alexandra; Baltazar, Telmo; Mendes, Ana-Reis; Oliveira, Paula A.; Costa, Vera Marisa; Ferreira, Rita; Duarte, José A.. Corresponding author: Moreira-Pais, Alexandra. "Long-term effect of doxorubicin on skeletal muscle oxidative stress in aged mice". Paper presented in Ciência 2022 - Encontro com a Ciência e Tecnologia em Portugal, 2022.
  21. Rodrigues, Patrícia; Sofia R, Brandão; Ferreira, Rita; Costa, Vera Marisa. "Impacto da quimioterapia com mitoxantrona na regeneração cardíaca". Paper presented in XIII Biochemistry Day - The Biochemistry of The Mood, 2022.
  22. Sofia R, Brandão; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera Marisa. "Unveiling the chronic cardiotoxic effects of doxorubicin on cardiac remodeling using a mouse model". Paper presented in Ciência 2022 – Science and Technology in Portugal Summit, 2022.
  23. Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Ferreira, Rita; Fernandes, Eduarda; Sá, Susana I; Sá SI; Capela, João Paulo; Carvalho, Félix; Costa, Vera Marisa. "Evaluation of mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Paper presented in AIMS Meeting, 2022.
  24. Sofia R, Brandão; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera Marisa. "Agravamento tardio dos efeitos moleculares subjacentes a cardiotoxicidade crónica da doxorrubicina num modelo de murganho". Paper presented in 3rd National Meeting of Young Researchers on Oncology (III ENJIO), 2021.
  25. Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho, Félix; et al. "A neurotoxicidade de longo prazo da doxorrubicina no cérebro de ratinhos CD-1 adultos.". Paper presented in 3º Encontro Nacional de Jovens Investigadores em Oncologia, Porto, Portugal, 2021.
  26. Serras, Ana S; Camões, Sérgio P; Antunes, Bernardo; Dionísio, F; Costa, Vera M; Yazar, Volkan; Vitorino, R; et al. "The secretome of mesenchymal stem cells ameliorates the cytotoxic effects of doxorubicin in non-tumoral cells". Paper presented in EUROTOX 2021 ¿ 56th Congress of the European Societies of Toxicology, 2021.
  27. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; Costa, Vera Marisa; Beatriz L. Pires-Lima; Correia, Xavier Cruz; Hugo F. Costa-Almeida; García-Mera, Xerardo; J. E. Rodriguez-Borges. Corresponding author: Ivo E. Sampaio-Dias. "The design of New Trofinetide® Conjugates Using Constrained Prolines". Paper presented in Encontro Nacional da Sociedade Portuguesa de Química, 2021.
  28. Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho, Félix; et al. Corresponding author: Dias-Carvalho, Ana. "The neurotoxicity of doxorubicin in the brain of adult CD-1 mice". Paper presented in Ciência 2021 ¿ Science and Technology in Portugal Summit, Lisbon, Portugal, 2021.
  29. Serras, Ana S.; Camões, Sérgio P.; Antunes, Bernardo C.; Dionísio, F; Costa, Vera M; Yazar, Volkan; Vitorino, R; et al. "The Mesenchymal Stem Cells Secretome Modulates Doxorubicin-induced Effects on Non-tumour Breast and Cardiac Cells". Paper presented in iMed.ULisboa meeting 2021, 2021.
  30. Sofia R, Brandão; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria João; Carvalho, Félix; Costa, Vera Marisa. "Unveiling the effects of doxorubicin and mitoxantrone on cardiac metabolism, homeostasis and autophagy in a mice model". Paper presented in III Iberian Journeys of Toxicology (III JIT), 2021.
  31. Sofia R, Brandão; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera Marisa. "Disclosing the cardiotoxic effects of the anticancer agentes doxorubicin and mitoxantrone on cardiac metabolism, homeostasis and autophagy using CD-1 mice". Paper presented in Ciência 2021 – Science and Technology in Portugal Summit, 2021.
  32. Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Carvalho, Félix; Ferreira, Rita; Costa, Vera. "Evaluation of doxorubicin and mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Paper presented in 14th Meeting of young researches of U. Porto (IJUP ¿21), 2021.
  33. Dias-Carvalho, Ana; Fernandes, Ana Olivía ; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Capela, João Paulo; Sá, Susana Isabel; Costa, Vera Marisa. "Chemobrain: assessing the potential to recovery from doxorubicin-induced-neurotoxic effects in CD-1 mice". Paper presented in 14º Encontro de Investigação Jovem da U. Porto (IJUP ¿21), 2021.
  34. Reis-Mendes, Ana; ESPINCHO, FRANCISCA; Margarida Duarte-Araújo; Duarte, José Alberto; Remião, Fernando; Emilia Sousa; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa. Corresponding author: ESPINCHO, FRANCISCA. "Short-term and long term renal and hepatic toxicity of doxorubicin". Paper presented in 14º Encontro de Investigação Jovem da Universidade do Porto, 2021.
  35. Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Carvalho, Félix; Ferreira, Rita; Costa, Vera. "Doxorubicin and mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Paper presented in XII Biochemistry Day, 2021.
  36. Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Maria de Lourdes Bastos; Carvalho, Félix; Sá, Susana I; Sá SI; Capela, João Paulo; Costa, Vera Marisa. "Chemobrain: evaluation of doxorubicin and mitoxantrone neurotoxicity in cd-1 mice". Paper presented in SPF Meeting 2021 - Sociedade Portuguesa de Farmacologia, 2021.
  37. Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho, Félix; et al. Corresponding author: Dias-Carvalho, Ana. "The long-term neurotoxicity of doxorubicin in the brain of adult CD-1 mice". Paper presented in Congress of the European Societies of Toxicology (EUROTOX Congress 2021), 2021.
  38. Carvalho, Ana Rita; Reis-Mendes, Ana; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Sá, Susana I; Capela, João Paulo; et al. "Chemobrain study: differential effects of doxorubicin and mitoxantrone in the brain of CD-1 mice". Paper presented in 1st International Electronic Conference on Brain Science, 2020.
  39. Sá, Susana I; Sá SI; Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Maria de Lourdes Bastos; Capela, João Paulo; Costa, Vera Marisa. "Evaluation of doxorubicin and mitoxantrone neurotoxicity in cd-1 mice". Paper presented in SIFFUP - Simpósio de Investigação da FFUP, 2020.
  40. Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo Jorge; Bastos, Maria de Lourdes; de Pinho, Paula Guedes; Carvalho, Félix. "Application of in vivo metabolomics to evaluate the early pathways of toxicity triggered by human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)". Paper presented in 16th Annual Conference of Metabolomics Society - Metabolomics Online 2020, 2020.
  41. Carvalho, Ana Rita; Reis-Mendes, Ana; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Sá, Susana I; et al. "Neurotoxicidade da mitoxantrona e doxorrubicina: estudo in vivo em diferentes idades". Paper presented in 2º Encontro Nacional de Jovens Investigadores em Oncologia, 2020.
  42. Dias-Carvalho, Ana; Fernandes, Ana Olivía ; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Capela, João Paulo; Sá, Susana Isabel; Costa, Vera Marisa. "Doxorubicin Increases Apoptotic Markers in the hipocampal formation of CD-1 mice". Paper presented in VI jornadas da Bioquímica: ¿O passaporte para a inovação¿, 2020.
  43. Sánchez-Momblona, Marina; Dionísio, Flávio; Reis-Mendes, Ana Filipa ; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria De Lourdes; Costa, Vera M. "The effects of doxorubicin and mitoxantrone in the spleen of mice at different ageing stages". Paper presented in 13rd Meeting of young researchers of University Porto, 2020.
  44. Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Sá, Susana I; Sá SI; Capela, João Paulo; Costa, Vera Marisa. "The effects of doxorubicin and mitoxantrone in mice brain at different aging stages: an in vivo chemobrain study". Paper presented in SPF 2020 ¿ Reunião Anual da Sociedade Portuguesa de Farmacologia, 2020.
  45. Ana Dias Carvalho; Ana Reis Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Sá, Susana I; Sá SI; Capela, João Paulo; Costa, Vera Marisa. "The effects of doxorubicin and mitoxantrone in the brain of different age mice: in vivo chemobrain study". Paper presented in 13th Meeting of Young researchers of University of Porto (IJUP), 2020.
  46. Rodrigues, Daniela; Costa, Vera M; Bastos, Maria De Lourdes; Carvalho, Félix. "Effects of alpha-amanitin in HepG2 cells are not prevented by drugs used in Amanita phalloides intoxications". Paper presented in EUROTOX 2019 - 55th Annual Meeting of the Society of the European Toxicology Society, 2019.
  47. Dionísio, Flávio; Duarte-Araujo, Margarida; Bastos, Maria De Lourdes; Carvalho, Félix; Costa, Vera M. "Cyclophosphamide metabolites 4-hydroxycyclophosphamide and acrolein exert strenuous cardiotoxicity in AC16 human cardiomyocytes, at clinical relevant concentrations". Paper presented in EUROTOX 2019 - 55th Annual Meeting of the Society of the European Toxicology Society, 2019.
  48. Carvalho, Ana Rita; Reis-Mendes, Ana Filipa; Duarte-Araujo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "Doxorubicin and mitoxantrone effects on the brain of differently aged mice: an in vivo chemobrain study". Paper presented in 55th Annual Meeting of the Society of the European Toxicology Society - EUROTOX 2019, 2019.
  49. Aires, A; Costa, Vera M; Brandão, Sofia; Ferreira, Rita. "Disclosing the molecular mechanisms underlying sarcopenia". Paper presented in XI Biochemistry Day - The challenges and the opportunities of Biochemistry, University of Aveiro, Aveiro, Portugal, 2019.
  50. Reis-Mendes, Ana Filipa; Duarte-Araujo, M.; Duarte, José Alberto; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Sousa, Emilia; Costa, Vera M. "Mitoxantrone-induced toxicity in different age male CD-1 mice.". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation "The Clocks of Metabolism and Disease", Coimbra, Portuga, 2019.
  51. Reis-Mendes, Ana Filipa; Duarte-Araújo, Margarida; Duarte, José Alberto; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera M. "Evaluation of the toxicity induced by doxorubicin in different age male CD-1 mice". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation "The Clocks of Metabolism and Disease", Coimbra, Portugal, 2019.
  52. Rodrigues, Daniela; Costa, Vera M; Bastos, Maria de Lourdes; Carvalho, Félix. "N-Acetylcysteine, silibinin and benzylpenicillin do not confer protection against a-amanitin cytotoxicity in HepG2 and HepaRG cells". Paper presented in 58th Annual Meeting of the Society of Toxicology, Baltimore, Maryland, EUA, 2019.
  53. Costa, Vera M; Capela, João Paulo; Silveira, CM; Rodrigues, Patrícia; Eleutério, Rute; Dores-Sousa, José Luís; Carvalho, Rui A; et al. "Mitoxantrone prompts early energetic and proteomic changes in HL-1 cardiomyocytes and late oxidative stress in clinically relevant doses.". Paper presented in 58th Annual Meeting of the Society of Toxicology, Baltimore, Maryland, EUA, 2019.
  54. Dias-Carvalho, Ana; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria Lourdes; Capela, João Paulo; Costa, Vera Marisa. "Differential effects of doxorubicin and mitoxantrone in the brain redox status of differently aged mice". Paper presented in 10th Annual International (bio)Medical Students Meeting, 2019.
  55. Carvalho, Ana Rita; Reis-Mendes, Ana Filipa; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "The effects of doxorubicin and mitoxantrone in brain glutathione levels of differently aged mice". Paper presented in Translational Research at iMed Conference® 10.0 | Lisboa 2018, Lisboa, Portugal, 2018.
  56. Soares, Jorge; Costa, Vera M; Bronze, Susana; Gaspar, Helena; Santos, Susana; Bastos, Maria De Lourdes; Carvalho, Félix; Capela, João Paulo. "Neurotoxicity of synthetic cathinones and evaluation of putative neuroprotectors". Paper presented in Innovations in Pharmacy. Advances & perspectives (IPAP18), Salamanca, Spain, 2018.
  57. Soares, Jorge; Costa, Vera M; Bronze, Susana; Gaspar, Helena; Santos, Susana; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo. "Clorgyline and N-acetyl-L-cysteine provide partial protection against the toxicity of synthetic cathinones and methamphetamine on SH-SY5Y humans cells". Paper presented in 54th Congress of European Societies of Toxicology, (Eurotox 2018) Brussels, Belgium, 2018.
  58. Reis-Mendes, Ana; Carvalho, Félix; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera M. "Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Metabolites in H9c2 Cardiac Differentiated Cells". Paper presented in 54th Congress of European Societies of Toxicology, (Eurotox 2018) Brussels, Belgium, 2018.
  59. Guedes, Rita; Cravo, Sara; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera M. "The influence of metabolism on MTX-induced toxicity: a pharmacokinetic study using adult and infant male CD-1 mice". Paper presented in Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry (MedChemSicily2018), Palermo, Italy, 2018.
  60. Reis-Mendes, Ana; Carvalho, Félix; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera M. "Main metabolites of 5-fluorouracil + adriamycin + cyclophosphamide (FAC) are not major contributors to FAC toxicity in H9c2 cardiac differentiated cells". Paper presented in International Symposium - MitoPorto - mitochondrial evolution, metabolism and disease, Porto, Portugal, 2018.
  61. Brandão, Sofia; Ferreira, Rita; Vitorino, Rui; Costa, Vera M. "Exploring the cardiotoxic effect of anticancer drugs using a network-based approach". Paper presented in Novel Therapeutic Strategies for Noncommunicable Diseases (NoTeS), Faculdade de Medicina – Universidade do Porto, Porto, Portugal, 2018.
  62. Guedes, Rita; Reis-Mendes, Ana; Gonçalves-Monteiro, Salomé; Capas, Sara; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera M. "The influence of age on mitoxantrone-induced toxicity: an in vivo study using adult and infant CD-1 male mice". Paper presented in XI Encontro Nacional de Estudantes de Bioquímica, Porto, Portugal, 2018.
  63. Costa, Vera M; Capela, João Paulo; Silveira, Célia M; Eleutério, Rute P; Rodrigues, Patrícia RS; Bastos, Maria de Lourdes; Alberto, José Alberto; et al. "Mitoxantrone elicits oxidative stress and proteomic changes in HL-1 cardiomyocytes at clinically relevant doses". Paper presented in Escola de Inverno de Farmácia - 3ª Edição (EIF2018), Porto, Portugal, 2018.
  64. Alves, Marisa; Reis-Mendes, Ana; Carvalho, Félix; Remião, Fernando; Bastos, Maria Bastos; Costa, Vera M. "An in vitro study with differentiated and non-differentiated H9c2 cells to evaluate pixantrone cardiotoxicity". Paper presented in 11st Meeting of young researchers of University Porto (IJUP ’18), Porto, Portugal, 2018.
  65. Guedes, Rita; Reis-Mendes, Ana; Gonçalves-Monteiro, Salomé; Capas, Sara; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera M. "Mitoxantrone-induced toxicity in adult and infant male CD-1 mice". Paper presented in 11st Meeting of young researchers of University Porto (IJUP ’18), Porto, Portugal, 2018.
  66. Loureiro, Sara; Costa, Vera M; Duarte, José Alberto; Duarte-Araújo, Margarida; Gonçalves-Monteiro, Salomé; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo. "Methylphenidate evokes heart and kidney toxicity in adolescent rats exposed one-week to relevant oral doses". Paper presented in Lisbon Addictions 2017, Lisboa, Portugal, 2017.
  67. Hrynchak, Ivanna; Sousa, Emília; Bastos, Maria de Lourdes; Pinto, Madalena; Costa, Vera M. "Studies towards the synthesis of dicarboxylic acid metabolite of mitoxantrone". Paper presented in 12nd International YES Meeting, Porto, Portugal, 2017.
  68. Pinho, Rita; Almeida, Daniela; Soares, Jorge; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo; Costa, Vera M. "Mitoxantrone was more neurotoxic than doxorubicin in SH-5YSY human cells". Paper presented in 10th Meeting of young researchers of University Porto (IJUP ’17), Porto, Portugal, 2017.
  69. Hrynchak, Ivanna; Sousa, Emília; Pinto, Madalena; Bastos, Maria de Lourdes; Costa, Vera M; Hrynchak, Ivanna; Bastos, M.L; Costa, Vera Marisa. "Synthesis and characterization of the main metabolites of mitoxantrone". Paper presented in 10th Meeting of young researchers of University Porto (IJUP ’17), Porto, Portugal, 2017.
  70. Hrynchak, Ivanna; Sousa, Emília; Bastos, Maria de Lourdes; Pinto, Madalena; Costa, Vera M. "The main metabolites of mitoxantrone: synthesis and structure elucidation". Paper presented in Escola de Inverno de Farmácia - 2ª Edição (EIF2017), Porto, Portugal, 2017.
  71. Boieng, Joana; Ribeiro, Daniela; Costa, Vera M; Visentainer, JV; Freitas, Marisa; Fernandes, Eduarda. "Bactris setosa, an underexploited brazilian fruit, shows protective effects against oxidative cellular damage". Paper presented in Sociedade Portuguesa de Química - Divisão de Química Alimentar, Porto, Portugal, 2016.
  72. Soares, Jorge; Costa, Vera M; Bronze, Susana; Gaspar, Helena; Santos, Susana; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo. "Neurotoxicity of synthetic cathinones on differentiated SH-SY5Y human dopaminergic cells". Paper presented in 52nd Congress of European Societies of Toxicology, (Eurotox 2016) Seville, Spain, 2016.
  73. Reis-Mendes, Ana; Gomes, Ana Sara; Carvalho, R.A.; Remião, Fernando; Carvalho, Félix; Pinto, Madalena; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera. "Unveiling the cardiotoxicity of anticancer drugs: A comparative in vitro study between mitoxantrone and its naphthoquinoxaline metabolite". Paper presented in 51st Congress of the European Societies of Toxicology (Eurotox 2015), 2015.
  74. Reis-Mendes, Ana; Gomes, Ana Sara; Carvalho, R.A.; Remião, Fernando; Carvalho, Félix; Pinto, Madalena; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera. "The cardiotoxicity of mitoxantrone: A comparative in vitro study between mitoxantrone and its naphthoquinoxaline metabolite". Paper presented in IJUP¿15 ¿ 8th Meeting of Your Researchers of the University of Porto, 2015.
  75. Dores-Sousa, José Luís; Duarte, José Alberto; Seabra, Vítor; Bastos, Maria Lourdes; Carvalho, Félix Dias; Costa, Vera M. "Mitoxantrone's multiple cardiac targets: the age factor for toxicity". Paper presented in 50th Congress of European Societies of Toxicology, (Eurotox 2014), 2014.
  76. Rodrigues, Patrícia; Eleutério, Rute; Silveira, Célia; Costa, Vera M; Almeida, Maria Gabriela. "Why is Mitoxantrone a poison to the heart?". Paper presented in VII Encontro Nacional de Estudantes de Bioquímica, (ENEBIOQ 2014) Faculty of Nova of Sciences and Technology, 2014.
  77. Silva, Renata; Costa, Vera M; Vitorino, Rui; Amado, Francisco; Carvalho, Félix Dias; Bastos, Maria De Lourdes; Carvalho, Rui Albuquerque; Remião, Fernando. "Effect of adrenaline oxidation process in the protein content of freshly isolated cardiomyocytes". Paper presented in 4th Annual Meeting of the Portuguese Network (Procura) 1st Meeting of the Portuguese National Mass Proteomics Spectrometry Network (RNEM) (Meeting ProCura RNEM 2007), 2007.
Encyclopedia entry
  1. Costa, Vera M; Rossato, Luciana G.; Milandri, Elisa; Nardi, Jessica; Teixeira, Patrícia; Mladenka, Premysl; Remião, Fernando. "Trace amines". In Scholarly Community Encyclopedia, 2022.
    Published
Journal article
  1. Silva-Reis, Sara C.; Costa, Vera M; Correia da Silva, Daniela; Pereira, David M.; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; García-Mera, Xerardo; Rodríguez-Borges, José E.; Sampaio-Dias, Ivo E.. "Exploring structural determinants of neuroprotection bias on novel glypromate conjugates with bioactive amines". European Journal of Medicinal Chemistry 267 (2024): 116174. http://dx.doi.org/10.1016/j.ejmech.2024.116174.
    Published • 10.1016/j.ejmech.2024.116174
  2. Reis-Mendes, Ana; Vitorino-Oliveira, Cláudia; Ferreira, Mariana; Carvalho, Félix; Remião, Fernando; Sousa, Emília; de Lourdes Bastos, Maria; Costa, Vera M. Corresponding author: Costa, Vera M. "Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin’s Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug". Cardiovascular Toxicology 24 3 (2024): 266-279. http://dx.doi.org/10.1007/s12012-024-09829-6.
    Published • 10.1007/s12012-024-09829-6
  3. Rocha, Sónia; Amaro, Andreia; Ferreira-Junior, Marcos D.; Proença, Carina; Silva, Artur M. S.; Costa, Vera M; Oliveira, Sara; et al. "Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes Mellitus". Pharmaceutics 16 2 (2024): 261. http://dx.doi.org/10.3390/pharmaceutics16020261.
    Published • 10.3390/pharmaceutics16020261
  4. Sara C. Silva-Reis; Costa, Vera Marisa; da Silva, Daniela Correia; Pereira, David; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; García-Mera, Xerardo; J. E. Rodriguez-Borges; Ivo E. Sampaio-Dias. Corresponding author: Ivo E. Sampaio-Dias. "Exploring Structural Determinants of Neuroprotection Bias on Novel Glypromate Conjugates with Bioactive Amines". European Journal of Medicinal Chemistry (2024):
    Accepted
  5. Dias-Carvalho, Ana; Sá, Susana Isabel; Carvalho, Félix; Fernandes, Eduarda; Costa, Vera M. Corresponding author: Costa, Vera M. "Inflammation as common link to progressive neurological diseases". Archives of Toxicology 98 1 (2024): 95-119. http://dx.doi.org/10.1007/s00204-023-03628-8.
    Open access • 10.1007/s00204-023-03628-8
  6. Reis-Mendes, A.; Vitorino-Oliveira, Claúdia; Remião, Fernando; Carvalho, Félix; Sousa, Emília; Bastos, Maria De Lourdes; Costa, Vera M. Corresponding author: Costa, Vera M. "Comparative in vitro study of the cytotoxic effects of doxorubicin's main metabolites on cardiac AC16 cells versus the parent drug". Cardiovascular Toxicology (2024):
    Accepted
  7. Carneiro, Patrícia; Ferreira, Mariana; Costa, Vera M; Carvalho, Félix; Capela, João Paulo. "Protective effects of amphetamine and methylphenidate against dopaminergic neurotoxicants in SH-SY5Y cells". Current Research in Toxicology 6 (2024): 100165. http://dx.doi.org/10.1016/j.crtox.2024.100165.
    10.1016/j.crtox.2024.100165
  8. Ferreira, Mariana; Carneiro, Patrícia; Costa, Vera Marisa; Carvalho, Félix; Meisel, Andreas; Capela, João Paulo. "Amphetamine and methylphenidate potential on the recovery from stroke and traumatic brain injury: A review". Reviews in the Neurosciences (2024):
    Submitted
  9. Dias-Carvalho, Ana; Ferreira, Mariana; Reis-Mendes, Ana; Ferreira, Rita; Bastos, Maria de Lourdes; Fernandes, Eduarda; Sá, Susana I; Sá SI; et al. Corresponding author: Dias-Carvalho, Ana. "Doxorubicin-induced neurotoxicity differently affects the hippocampal formation subregions in adult mice". Heliyon (2024):
    Accepted
  10. Sara C. Silva-Reis; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Maronde, DAIANE; Costa, Vera Marisa; García-Mera, Xerardo; et al. Corresponding author: Ivo E. Sampaio-Dias. "Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors". ACS Med. Chem. Lett. (2023): https://doi.org/10.1021/acsmedchemlett.3c00264.
    Published
  11. Reis-Mendes, Ana; Carvalho, Félix; Remião, Fernando; Sousa, Emília; de Lourdes Bastos, Maria; Costa, Vera M; Reis-Mendes, A.; et al. Corresponding author: Costa, Vera M. "Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells". Archives of Toxicology 97 1 (2023): 201-216. http://dx.doi.org/10.1007/s00204-022-03363-6.
    Published • 10.1007/s00204-022-03363-6
  12. Wu, Dongze; Jin, Yingzhao; Xing, Yuhan; Abate, Melsew Dagne; Abbasian, Mohammadreza; Abbasi-Kangevari, Mohsen; Abbasi-Kangevari, Zeinab; et al. "Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019". eClinicalMedicine 64 (2023): 102193. http://dx.doi.org/10.1016/j.eclinm.2023.102193.
    Open access • 10.1016/j.eclinm.2023.102193
  13. Reis-Mendes, Ana; Ferreira, Mariana; Duarte, José Alberto; Duarte-Araújo, Margarida; Remião, Fernando; Carvalho, Félix; Sousa, Emília; Bastos, Maria Lourdes; Costa, Vera M. Corresponding author: Costa, Vera M. "The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice". Archives of Toxicology 97 12 (2023): 3163-3177. http://dx.doi.org/10.1007/s00204-023-03586-1.
    Published • 10.1007/s00204-023-03586-1
  14. Dias-Carvalho, Ana; Margarida-Araújo, Ana; Reis-Mendes, Ana; Sequeira, Catarina Oliveira; Pereira, Sofia Azeredo; Guedes de Pinho, Paula; Carvalho, Félix; et al. Corresponding author: Costa, Vera M. "A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain: A Metabolomics Study". International Journal of Molecular Sciences 24 17 (2023): 13126. http://dx.doi.org/10.3390/ijms241713126.
    Published • 10.3390/ijms241713126
  15. Sousa, Adelaide; Azevedo, Rui; Costa, Vera M; Oliveira, Sara; Preguiça, Inês; Viana, Sofia; Reis, Flávio; et al. "Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice". Archives of Toxicology 97 10 (2023): 2643-2657. http://dx.doi.org/10.1007/s00204-023-03558-5.
    Published • 10.1007/s00204-023-03558-5
  16. Brandão, Sofia; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria; Rocha, Hugo; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. Corresponding author: Costa, Vera M. "Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice". Biomolecules 13 6 (2023): 921. http://dx.doi.org/10.3390/biom13060921.
    10.3390/biom13060921
  17. Costa, Vera M; Capela, João Paulo; Bastos, Maria Lourdes; Remião, Fernando; Varner, Kurt James; Duarte, José Alberto; Carvalho, Félix; et al. Corresponding author: Carvalho, Félix. "Study of the potential toxicity of adrenaline to neurons, using the SH-SY5Y human cellular model". Brazilian Journal of Pharmaceutical Sciences 59 (2023): e20467. http://dx.doi.org/10.1590/s2175-97902023e20467.
    Published • 10.1590/s2175-97902023e20467
  18. Silva-Reis, Sara C.; Sampaio-Dias, Ivo E.; Costa, Vera M; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; García-Mera, Xerardo; Rodríguez-Borges, José E.. "Concise Overview of Glypromate Neuropeptide Research: From Chemistry to Pharmacological Applications in Neurosciences". ACS Chemical Neuroscience 14 4 (2023): 554-572. http://dx.doi.org/10.1021/acschemneuro.2c00675.
    Published • 10.1021/acschemneuro.2c00675
  19. Reis-Mendes, A.; Ferreira, Mariana; Padrão, Ana Isabel; Duarte, Jose Alberto; Duarte-Araújo, M.; Remiao, F.; Carvalho, Félix; et al. Corresponding author: Costa, Vera M. "The Role of Nrf2 and Inflammation on the Dissimilar Cardiotoxicity of Doxorubicin in Two-Time Points: a Cardio-Oncology In Vivo Study Through Time". Inflammation (2023):
    Accepted
  20. Costa, Vera M; Grando, Luciana Grazziotin Rossato; Milandri, Elisa; Nardi, Jessica; Teixeira, Patrícia; Mladenka, Premysl; Remião, Fernando. Corresponding author: Remião, Fernando. "Natural Sympathomimetic Drugs: From Pharmacology to Toxicology". Biomolecules 12 12 (2022): 1793. http://dx.doi.org/10.3390/biom12121793.
    Open access • Published • 10.3390/biom12121793
  21. Remião, Fernando; Carmo, Helena; Gomes, Miguel; Silva, Renata; Costa, Vera Marisa; Carvalho, Félix; Bastos, Maria de Lourdes; et al. Corresponding author: Remião, Fernando. "The impact of video lecture capture on student attainment and achievement of intended learning outcomes". Pharmacy Education 22 1 (2022): 843-855. http://dx.doi.org/10.46542/pe.2022.221.843855.
    Published • 10.46542/pe.2022.221.843855
  22. Brandão, Sofia Reis; Carvalho, Félix; Amado, Francisco; Ferreira, Rita; Costa, Vera M. Corresponding author: Costa, Vera M. "Insights on the molecular targets of cardiotoxicity induced by anticancer drugs: A systematic review based on proteomic findings". Metabolism 134 (2022): 155250. http://dx.doi.org/10.1016/j.metabol.2022.155250.
    Published • 10.1016/j.metabol.2022.155250
  23. Garcia, Juliana; Carvalho, Alexandra; das Neves, Ricardo Pires; Malheiro, Rui; Rodrigues, Daniela F.; Figueiredo, Pedro R.; Bovolini, Antonio; et al. "Antidotal effect of cyclosporine A against a-amanitin toxicity in CD-1 mice, at clinical relevant doses". Food and Chemical Toxicology 166 (2022): 113198. http://dx.doi.org/10.1016/j.fct.2022.113198.
    10.1016/j.fct.2022.113198
  24. Tran, Khanh Bao; Lang, Justin J; Compton, Kelly; Xu, Rixing; Acheson, Alistair R; Henrikson, Hannah Jacqueline; Kocarnik, Jonathan M; et al. "The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 400 10352 (2022): 563-591. http://dx.doi.org/10.1016/s0140-6736(22)01438-6.
    Published • 10.1016/s0140-6736(22)01438-6
  25. Sharma, Rajesh; Abbasi-Kangevari, Mohsen; Abd-Rabu, Rami; Abidi, Hassan; Abu-Gharbieh, Eman; Acuna, Juan Manuel; Adhikari, Sangeet; et al. "Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet Gastroenterology & Hepatology 7 7 (2022): 627-647. http://dx.doi.org/10.1016/s2468-1253(22)00044-9.
    Published • 10.1016/s2468-1253(22)00044-9
  26. Dias-Carvalho, Ana; Ferreira, Mariana; Reis-Mendes, Ana; Ferreira, Rita; Bastos, Maria Lourdes; Fernandes, Eduarda; Sá, Susana Isabel; et al. Corresponding author: Costa, Vera M. "Chemobrain: mitoxantrone-induced oxidative stress, apoptotic and autophagic neuronal death in adult CD-1 mice". Archives of Toxicology 96 6 (2022): 1767-1782. http://dx.doi.org/10.1007/s00204-022-03261-x.
    Published • 10.1007/s00204-022-03261-x
  27. Kocarnik, Jonathan M.; Compton, Kelly; Dean, Frances E.; Fu, Weijia; Gaw, Brian L.; Harvey, James D.; Henrikson, Hannah Jacqueline; et al. "Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019". JAMA Oncology 8 3 (2022): 420. http://dx.doi.org/10.1001/jamaoncol.2021.6987.
    Published • 10.1001/jamaoncol.2021.6987
  28. Nichols, Emma; Steinmetz, Jaimie D; Vollset, Stein Emil; Fukutaki, Kai; Chalek, Julian; Abd-Allah, Foad; Abdoli, Amir; et al. "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019". The Lancet Public Health 7 2 (2022): e105-e125. http://dx.doi.org/10.1016/s2468-2667(21)00249-8.
    Published • 10.1016/s2468-2667(21)00249-8
  29. Moreira-Pais, Alexandra; Ferreira, Rita; Costa, Vera; Oliveira P.; Duarte, José Alberto. "The molecular mechanisms involved in doxorubicin-induced skeletal muscle wasting". Revista Portuguesa de Cirurgia 51 (2022): 13-22.
    Published • 10.34635/rpc.930
  30. Dionísio, Flávio; Araújo, Ana Margarida; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix; Costa, Vera Marisa. Corresponding author: Costa, Vera Marisa. "Cardiotoxicity of cyclophosphamide’s metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes". Archives of Toxicology 96 2 (2022): 653-671. http://dx.doi.org/10.1007/s00204-021-03204-y.
    10.1007/s00204-021-03204-y
  31. Alvarez, Elysia M; Force, Lisa M; Xu, Rixing; Compton, Kelly; Lu, Dan; Henrikson, Hannah Jacqueline; Kocarnik, Jonathan M; et al. "The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet Oncology 23 1 (2022): 27-52. http://dx.doi.org/10.1016/s1470-2045(21)00581-7.
    Published • 10.1016/s1470-2045(21)00581-7
  32. Serras, Ana S.; Camões, Sérgio P.; Antunes, Bernardo; Costa, Vera M.; Dionísio, Flávio; Yazar, Volkan; Vitorino, Rui; et al. "The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Doxorubicin-Induced Cytotoxicity: Impact in Non-Tumor Cells". International Journal of Molecular Sciences 22 23 (2021): 13072. http://dx.doi.org/10.3390/ijms222313072.
    Open access • Published • 10.3390/ijms222313072
  33. Reis-Mendes, Ana; Padrão, Ana Isabel; Duarte, José Alberto; Gonçalves-Monteiro, Salomé; Duarte-Araújo, Margarida; Remião, Fernando; Carvalho, Félix; et al. Corresponding author: Costa, Vera Marisa. "Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice". Biomolecules 11 11 (2021): 1725. http://dx.doi.org/10.3390/biom11111725.
    Open access • Published • 10.3390/biom11111725
  34. Dias-Carvalho, Ana; Ferreira, Mariana; Ferreira, Rita; Bastos, Maria de Lourdes; Sá, Susana Isabel; Capela, João Paulo; Carvalho, Félix; Costa, Vera Marisa. Corresponding author: Costa, Vera Marisa. "Four decades of chemotherapy-induced cognitive dysfunction: comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events". Archives of Toxicology 96 1 (2021): 11-78. http://dx.doi.org/10.1007/s00204-021-03171-4.
    Published • 10.1007/s00204-021-03171-4
  35. Safiri, Saeid; Kolahi, Ali-Asghar; Naghavi, Mohsen. "Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease study 2019". BMJ Global Health 6 11 (2021): e004128. http://dx.doi.org/10.1136/bmjgh-2020-004128.
    Published • 10.1136/bmjgh-2020-004128
  36. Kinyoki, Damaris; Osgood-Zimmerman, Aaron E.; Bhattacharjee, Natalia V.; Schaeffer, Lauren E.; Lazzar-Atwood, Alice; Lu, Dan; Ewald, Samuel B.; et al. "Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018". Nature Medicine 27 10 (2021): 1761-1782. http://dx.doi.org/10.1038/s41591-021-01498-0.
    Published • 10.1038/s41591-021-01498-0
  37. Ward, Joseph L; Azzopardi, Peter S; Francis, Kate Louise; Santelli, John S; Skirbekk, Vegard; Sawyer, Susan M; Kassebaum, Nicholas J; et al. "Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 398 10311 (2021): 1593-1618. http://dx.doi.org/10.1016/s0140-6736(21)01546-4.
    Published • 10.1016/s0140-6736(21)01546-4
  38. Soares, Jorge; Costa, Vera Marisa; Bastos, Maria De Lourdes; Carvalho, Félix; Capela, João Paulo. "An updated review on synthetic cathinones". Archives of Toxicology (2021): https://doi.org/10.1007/s00204-021-03083-3.
    Published • 10.1007/s00204-021-03083-3
  39. GBD 2019 Stroke Collaborators. "Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.". The Lancet. Neurology (2021): http://europepmc.org/abstract/med/34487721.
    10.1016/s1474-4422(21)00252-0
  40. Paulson, Katherine R; Kamath, Aruna M; Alam, Tahiya; Bienhoff, Kelly; Abady, Gdiom Gebreheat; Abbas, Jaffar; Abbasi-Kangevari, Mohsen; et al. "Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019". The Lancet 398 10303 (2021): 870-905. http://dx.doi.org/10.1016/s0140-6736(21)01207-1.
    Published • 10.1016/s0140-6736(21)01207-1
  41. Galles, Natalie C; Liu, Patrick Y; Updike, Rachel L; Fullman, Nancy; Nguyen, Jason; Rolfe, Sam; Sbarra, Alyssa N; et al. "Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1". The Lancet 398 10299 (2021): 503-521. http://dx.doi.org/10.1016/s0140-6736(21)00984-3.
    Published • 10.1016/s0140-6736(21)00984-3
  42. Reitsma, Marissa B; Kendrick, Parkes J; Ababneh, Emad; Abbafati, Cristiana; Abbasi-Kangevari, Mohsen; Abdoli, Amir; Abedi, Aidin; et al. "Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019". The Lancet 397 10292 (2021): 2337-2360. http://dx.doi.org/10.1016/s0140-6736(21)01169-7.
    10.1016/s0140-6736(21)01169-7
  43. Reis-Mendes, Ana; Dores-Sousa, José Luís; Padrão, Ana Isabel; Duarte-Araújo, Margarida; Duarte, José Alberto; Seabra, Vítor; Gonçalves-Monteiro, Salomé; et al. "Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice". Pharmaceuticals 14 6 (2021): 510. http://dx.doi.org/10.3390/ph14060510.
    10.3390/ph14060510
  44. Sampaio-Dias, Ivo E.; Reis-Mendes, Ana; Costa, Vera Marisa; García-Mera, Xerardo; Brea, José; Loza, María Isabel; Pires-Lima, Beatriz L.; et al. "Discovery of New Potent Positive Allosteric Modulators of Dopamine D2 Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide". Journal of Medicinal Chemistry 64 9 (2021): 6209-6220. http://dx.doi.org/10.1021/acs.jmedchem.1c00252.
    Published • 10.1021/acs.jmedchem.1c00252
  45. Brandão, Sofia Reis; Reis-Mendes, Ana; Domingues, Pedro; Duarte, José Alberto; Bastos, Maria Lourdes; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. Corresponding author: Costa, Vera M. "Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model". Toxicology 459 (2021): 152852. http://dx.doi.org/10.1016/j.tox.2021.152852.
    Published • 10.1016/j.tox.2021.152852
  46. Anjos, Miguel; Fontes-Oliveira, Marta; Costa, Vera M; Santos, Mário; Ferreira, Rita. "An update of the molecular mechanisms underlying doxorubicin plus trastuzumab induced cardiotoxicity". Life Sciences 280 (2021): 119760. http://dx.doi.org/10.1016/j.lfs.2021.119760.
    Published • 10.1016/j.lfs.2021.119760
  47. Roth, Gregory A.; Mensah, George A.; Johnson, Catherine O.; Addolorato, Giovanni; Ammirati, Enrico; Baddour, Larry M.; Barengo, Noël C.; et al. "Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019". Journal of the American College of Cardiology 76 25 (2020): 2982-3021. http://dx.doi.org/10.1016/j.jacc.2020.11.010.
    10.1016/j.jacc.2020.11.010
  48. Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo Jorge; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix. "In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)". Archives of Toxicology 95 2 (2020): 509-527. http://dx.doi.org/10.1007/s00204-020-02949-2.
    Published • 10.1007/s00204-020-02949-2
  49. Rufino, Ana T.; Costa, Vera M.; Carvalho, Félix; Fernandes, Eduarda. "Flavonoids as antiobesity agents: A review". Medicinal Research Reviews 41 1 (2020): 556-585. http://dx.doi.org/10.1002/med.21740.
    10.1002/med.21740
  50. Murray, Christopher J L; Aravkin, Aleksandr Y; Zheng, Peng; Abbafati, Cristiana; Abbas, Kaja M; Abbasi-Kangevari, Mohsen; Abd-Allah, Foad; et al. "Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1223-1249. http://dx.doi.org/10.1016/s0140-6736(20)30752-2.
    Published • 10.1016/s0140-6736(20)30752-2
  51. Vos, Theo; Lim, Stephen S; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasifard, Mitra; Abbasi-Kangevari, Mohsen; et al. "Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1204-1222. http://dx.doi.org/10.1016/s0140-6736(20)30925-9.
    10.1016/s0140-6736(20)30925-9
  52. Wang, Haidong; Abbas, Kaja M; Abbasifard, Mitra; Abbasi-Kangevari, Mohsen; Abbastabar, Hedayat; Abd-Allah, Foad; Abdelalim, Ahmed; et al. "Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1160-1203. http://dx.doi.org/10.1016/s0140-6736(20)30977-6.
    Open access • Published • 10.1016/s0140-6736(20)30977-6
  53. Murray, Christopher J L; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasi-Kangevari, Mohsen; Abd-Allah, Foad; Abdollahi, Mohammad; et al. "Five insights from the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1135-1159. http://dx.doi.org/10.1016/s0140-6736(20)31404-5.
    10.1016/s0140-6736(20)31404-5
  54. Lozano, Rafael; Fullman, Nancy; Mumford, John Everett; Knight, Megan; Barthelemy, Celine M; Abbafati, Cristiana; Abbastabar, Hedayat; et al. "Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1250-1284. http://dx.doi.org/10.1016/s0140-6736(20)30750-9.
    Open access • 10.1016/s0140-6736(20)30750-9
  55. Costa, Vera Marisa; Capela, João Paulo; Sousa, Joana R.; Eleutério, Rute P.; Rodrigues, Patrícia R. S.; Dores-Sousa, José Luís; Carvalho, Rui A.; et al. "Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations". Archives of Toxicology 94 12 (2020): 4067-4084. http://dx.doi.org/10.1007/s00204-020-02874-4.
    10.1007/s00204-020-02874-4
  56. James, Spencer L; Castle, Chris D; Dingels, Zachary V; Fox, Jack T; Hamilton, Erin B; Liu, Zichen; Roberts, Nicholas L S; et al. "Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study". Injury Prevention 26 Suppl 2 (2020): i125-i153. http://dx.doi.org/10.1136/injuryprev-2019-043531.
    10.1136/injuryprev-2019-043531
  57. Wiens, Kirsten E; Lindstedt, Paulina A; Blacker, Brigette F; Johnson, Kimberly B; Baumann, Mathew M; Schaeffer, Lauren E; Abbastabar, Hedayat; et al. "Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17". The Lancet Global Health 8 8 (2020): e1038-e1060. http://dx.doi.org/10.1016/s2214-109x(20)30230-8.
    Published • 10.1016/s2214-109x(20)30230-8
  58. Reiner, Robert C; Wiens, Kirsten E; Deshpande, Aniruddha; Baumann, Mathew M; Lindstedt, Paulina A; Blacker, Brigette F; Troeger, Christopher E; et al. "Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Study 2017". The Lancet 395 10239 (2020): 1779-1801. http://dx.doi.org/10.1016/s0140-6736(20)30114-8.
    10.1016/s0140-6736(20)30114-8
  59. Kamangar, Farin; Nasrollahzadeh, Dariush; Safiri, Saeid; Sepanlou, Sadaf G; Fitzmaurice, Christina; Ikuta, Kevin S; Bisignano, Catherine; et al. "The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet Gastroenterology & Hepatology 5 6 (2020): 582-597. http://dx.doi.org/10.1016/s2468-1253(20)30007-8.
    Open access • 10.1016/s2468-1253(20)30007-8
  60. Soares, Jorge; Costa, Vera Marisa; Gaspar, Helena; Santos, Susana; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo. "Adverse outcome pathways induced by 3,4-dimethylmethcathinone and 4-methylmethcathinone in differentiated human SH-SY5Y neuronal cells". Archives of Toxicology 94 7 (2020): 2481-2503. http://dx.doi.org/10.1007/s00204-020-02761-y.
    10.1007/s00204-020-02761-y
  61. James, Spencer L; Castle, Chris D; Dingels, Zachary V; Fox, Jack T; Hamilton, Erin B; Liu, Zichen; S Roberts, Nicholas L; et al. "Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017". Injury Prevention 26 Suppl 2 (2020): i96-i114. http://dx.doi.org/10.1136/injuryprev-2019-043494.
    Published • 10.1136/injuryprev-2019-043494
  62. Kinyoki, Damaris K.; Ross, Jennifer M.; Lazzar-Atwood, Alice; Munro, Sandra B.; Schaeffer, Lauren E.; Abbasalizad-Farhangi, Mahdieh; Abbasi, Masoumeh; et al. "Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017". Nature Medicine 26 5 (2020): 750-759. http://dx.doi.org/10.1038/s41591-020-0807-6.
    10.1038/s41591-020-0807-6
  63. Daniela Ferreira Rodrigues; Ricardo Pires das Neves; Alexandra T. P. Carvalho; Maria Lourdes Bastos; Vera M. Costa; Félix Carvalho. "In vitro mechanistic studies on alpha-amanitin and its putative antidotes". Archives of Toxicology (2020): https://doi.org/10.1007/s00204-020-02718-1.
    10.1007/s00204-020-02718-1
  64. Sepanlou, Sadaf G; Safiri, Saeid; Bisignano, Catherine; Ikuta, Kevin S; Merat, Shahin; Saberifiroozi, Mehdi; Poustchi, Hossein; et al. "The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet Gastroenterology & Hepatology 5 3 (2020): 245-266. http://dx.doi.org/10.1016/s2468-1253(19)30349-8.
    Open access • Published • 10.1016/s2468-1253(19)30349-8
  65. Fitzmaurice, Christina; Abate, Degu; Abbasi, Naghmeh; Abbastabar, Hedayat; Abd-Allah, Foad; Abdel-Rahman, Omar; Abdelalim, Ahmed; et al. "Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017". JAMA Oncology 5 12 (2019): 1749. http://dx.doi.org/10.1001/jamaoncol.2019.2996.
    10.1001/jamaoncol.2019.2996
  66. Burstein, Roy; Henry, Nathaniel J.; Collison, Michael L.; Marczak, Laurie B.; Sligar, Amber; Watson, Stefanie; Marquez, Neal; et al. "Mapping 123 million neonatal, infant and child deaths between 2000 and 2017". Nature 574 7778 (2019): 353-358. http://dx.doi.org/10.1038/s41586-019-1545-0.
    Published • 10.1038/s41586-019-1545-0
  67. Force, Lisa M.; Abdollahpour, Ibrahim; Advani, Shailesh M; Agius, Dominic; Ahmadian, Elham; Alahdab, Fares; Alam, Tahiya; et al. "The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017". The Lancet Oncology 20 9 (2019): 1211-1225. http://dx.doi.org/10.1016/s1470-2045(19)30339-0.
    Published • 10.1016/s1470-2045(19)30339-0
  68. Dias-Carvalho, Ana; Reis-Mendes, A.; Duarte-Araújo, M.; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera Marisa. "Doxorubicin and mitoxantrone effects on the brain of differently aged mice: na in vivo chemobrain study". Toxicology Letters 314 (2019): 223-223.
    Published
  69. Rocha-Pereira C; Silva V; Costa VM; Silva R; Garcia J; Gonçalves-Monteiro S; Duarte-Araújo M; et al. "Histological and toxicological evaluation, in rat, of a P-glycoprotein inducer and activator: 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5).". EXCLI journal 18 (2019): 697-722. http://europepmc.org/abstract/med/31611753.
    10.17179/excli2019-1675
  70. Soares J; Costa VM; Gaspar H; Santos S; de Lourdes Bastos M; Carvalho F; Capela JP. "Structure-cytotoxicity relationship profile of 13 synthetic cathinones in differentiated human SH-SY5Y neuronal cells.". Neurotoxicology (2019): http://europepmc.org/abstract/med/31473217.
    10.1016/j.neuro.2019.08.009
  71. Rodrigues, Daniela F.; Costa, Vera M.; Silvestre, Ricardo; Bastos, Maria L.; Carvalho, Félix; Daniela F. Rodrigues; Vera M. Costa; et al. "Methods for the analysis of transcriptome dynamics". Toxicology Research 8 5 (2019): 597-612. http://dx.doi.org/10.1039/c9tx00088g.
    10.1039/c9tx00088g
  72. Feigin, Valery L; Nichols, Emma; Alam, Tahiya; Bannick, Marlena S; Beghi, Ettore; Blake, Natacha; Culpepper, William J; et al. "Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016". The Lancet Neurology 18 5 (2019): 459-480. http://dx.doi.org/10.1016/s1474-4422(18)30499-x.
    10.1016/s1474-4422(18)30499-x
  73. Garcia, Juliana; Costa, Vera Marisa; Bovolini, Antonio; Duarte, José Alberto; Rodrigues, Daniela Ferreira; de Lourdes Bastos, Maria; Carvalho, Félix. "An effective antidotal combination of polymyxin B and methylprednisolone for a-amanitin intoxication". Archives of Toxicology 93 5 (2019): 1449-1463. http://dx.doi.org/10.1007/s00204-019-02426-5.
    10.1007/s00204-019-02426-5
  74. Reis-Mendes, Ana; Carvalho, Félix; Remião, Fernando; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera Marisa. "The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells". Biomolecules 9 3 (2019): 98. http://dx.doi.org/10.3390/biom9030098.
    10.3390/biom9030098
  75. Maria Pereira-Oliveira; Ana Reis-Mendes; Félix Carvalho; Fernando Remião; Maria de Lourdes Bastos; Vera Marisa Costa. "Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells". Biomolecules (2019): https://doi.org/10.3390/biom9010021.
    10.3390/biom9010021
  76. R. Feio-Azevedo; V. M. Costa; D. J. Barbosa; A. Teixeira-Gomes; I. Pita; S. Gomes; F. C. Pereira; et al. "Aged rats are more vulnerable than adolescents to ecstasy-induced toxicity". Archives of Toxicology 92 7 (2018): 2275-2295. https://doi.org/10.1007/s00204-018-2226-8.
    10.1007/s00204-018-2226-8
  77. Almeida, Daniela; Pinho, Rita; Correia, Verónica; Soares, Jorge; Bastos, Maria; Carvalho, Félix; Capela, João; Costa, Vera. "Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A 'Chemobrain' In Vitro Study". Pharmaceuticals 11 2 (2018): 41. http://dx.doi.org/10.3390/ph11020041.
    10.3390/ph11020041
  78. Reis-Mendes, Ana; Alves, Marisa; Carvalho, Félix; Remião, Fernando; Bastos, Maria Lourdes; Costa, Vera Marisa. "Pixantrone, a new anticancer drug with the same old cardiac problems? An in vitro study with differentiated and non-differentiated H9c2 cells". Interdisciplinary Toxicology 11 1 (2018): 13-21. http://dx.doi.org/10.2478/intox-2018-0002.
    10.2478/intox-2018-0002
  79. Loureiro-Vieira, Sara; Costa, Vera Marisa; Duarte, José Alberto; Duarte-Araújo, Margarida; Gonçalves-Monteiro, Salomé; Maria de Lourdes, Bastos; Carvalho, Félix; Capela, João Paulo. "Methylphenidate clinically oral doses improved brain and heart glutathione redox status and evoked renal and cardiac tissue injury in rats". Biomedicine & Pharmacotherapy 100 (2018): 551-563. http://dx.doi.org/10.1016/j.biopha.2018.02.017.
    10.1016/j.biopha.2018.02.017
  80. Mladenka, Premysl; Applová, Lenka; Patocka, Jirí; Costa, Vera Marisa; Remiao, Fernando; Pourová, Jana; Mladenka, Aleš; et al. "Comprehensive review of cardiovascular toxicity of drugs and related agents". Medicinal Research Reviews 38 4 (2018): 1332-1403. http://dx.doi.org/10.1002/med.21476.
    10.1002/med.21476
  81. Hrynchak, Ivanna; Reis-Mendes, A.; Palmeira, A; Bastos, M.L; Costa, Vera M. "Old Pharmaceuticals with New Applications: the Case Studies of Lucanthone and Mitoxantrone.". 3rd International Electronic Conference on Medical Chemistry (2017): 4663. http://dx.doi.org/10.3390/ecmc-3-04663.
    10.3390/ecmc-3-04663
  82. Loureiro-Vieira, Sara; Costa, Vera Marisa; Lourdes Bastos, Maria; Carvalho, Félix; Capela, João Paulo. "Methylphenidate effects in the young brain: friend or foe?". International Journal of Developmental Neuroscience 60 1 (2017): 34-47. http://dx.doi.org/10.1016/j.ijdevneu.2017.04.002.
    Published • 10.1016/j.ijdevneu.2017.04.002
  83. Hrynchak, Ivanna; Sousa, Emília; Pinto, Madalena; Costa, Vera Marisa. "The importance of drug metabolites synthesis: the case-study of cardiotoxic anticancer drugs". Drug Metabolism Reviews 49 2 (2017): 158-196. http://dx.doi.org/10.1080/03602532.2017.1316285.
    10.1080/03602532.2017.1316285
  84. Boeing, Joana Schuelter; Ribeiro, Daniela; Chisté, Renan Campos; Visentainer, Jesuí Vergílio; Costa, Vera Marisa; Freitas, Marisa; Fernandes, Eduarda. "Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress". Food Chemistry 220 (2017): 427-437. http://dx.doi.org/10.1016/j.foodchem.2016.09.188.
    10.1016/j.foodchem.2016.09.188
  85. Feio-Azevedo, R.; Costa, V.M.; Ferreira, L.M.; Branco, P.S.; Pereira, F.C.; Bastos, M.L.; Carvalho, F.; Capela, J.P.. "Toxicity of the amphetamine metabolites 4-hydroxyamphetamine and 4-hydroxynorephedrine in human dopaminergic differentiated SH-SY5Y cells". Toxicology Letters 269 (2017): 65-76. http://dx.doi.org/10.1016/j.toxlet.2017.01.012.
    Published • 10.1016/j.toxlet.2017.01.012
  86. Rodrigues, Daniela; Freitas, Marisa; Marisa Costa, Vera; Arturo Lopez-Quintela, Manuel; Rivas, José; Freitas, Paulo; Carvalho, Félix; Fernandes, Eduarda; Silva, Paula. "Quantitative histochemistry for macrophage biodistribution on mice liver and spleen after the administration of a pharmacological-relevant dose of polyacrylic acid-coated iron oxide nanoparticles". Nanotoxicology 11 2 (2017): 256-266. http://dx.doi.org/10.1080/17435390.2017.1291865.
    10.1080/17435390.2017.1291865
  87. Reis-Mendes, A.; Gomes, A. S.; Carvalho, R. A.; Carvalho, F.; Remião, F.; Pinto, M.; Bastos, M. L.; Sousa, E.; Costa, V. M.. "Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy". Archives of Toxicology 91 4 (2016): 1871-1890. http://dx.doi.org/10.1007/s00204-016-1839-z.
    10.1007/s00204-016-1839-z
  88. Teixeira-Gomes, Armanda; Costa, Vera Marisa; Feio-Azevedo, Rita; Duarte, José Alberto; Duarte-Araújo, Margarida; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo. "Ecstasy toxicity to adolescent rats following an acute low binge dose". BMC Pharmacology and Toxicology 17 1 (2016): http://dx.doi.org/10.1186/s40360-016-0070-0.
    10.1186/s40360-016-0070-0
  89. Couto, Diana; Freitas, Marisa; Costa, Vera Marisa; Chisté, Renan Campos; Almeida, Agostinho; Lopez-Quintela, M. Arturo; Rivas, José; et al. "Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity". Journal of Applied Toxicology 36 10 (2016): 1321-1331. http://dx.doi.org/10.1002/jat.3323.
    10.1002/jat.3323
  90. Filipa Reis-Mendes, Ana; Sousa, Emília; de Lourdes Bastos, Maria; Marisa Costa, Vera. "The Role of the Metabolism of Anticancer Drugs in Their Induced-Cardiotoxicity". Current Drug Metabolism 17 1 (2015): 75-90. http://dx.doi.org/10.2174/1389200216666151103114926.
    10.2174/1389200216666151103114926
  91. Garcia, Juliana; Costa, Vera M.; Carvalho, Alexandra; Baptista, Paula; de Pinho, Paula Guedes; de Lourdes Bastos, Maria; Carvalho, Félix. "Amanita phalloides poisoning: Mechanisms of toxicity and treatment". Food and Chemical Toxicology 86 (2015): 41-55. http://dx.doi.org/10.1016/j.fct.2015.09.008.
    Published • 10.1016/j.fct.2015.09.008
  92. Garcia, Juliana; Costa, Vera Marisa; Carvalho, Alexandra T. P.; Silvestre, Ricardo; Duarte, José Alberto; Dourado, Daniel F. A. R.; Arbo, Marcelo D.; et al. "A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B". Archives of Toxicology 89 12 (2015): 2305-2323. http://dx.doi.org/10.1007/s00204-015-1582-x.
    Published • 10.1007/s00204-015-1582-x
  93. Garcia, Juliana; Costa, Vera M.; Costa, Ana Elisa; Andrade, Sérgio; Carneiro, Ana Cristina; Conceição, Filipe; Paiva, José Artur; et al. "Co-ingestion of amatoxins and isoxazoles-containing mushrooms and successful treatment: A case report". Toxicon 103 (2015): 55-59. http://dx.doi.org/10.1016/j.toxicon.2015.06.012.
    Published • 10.1016/j.toxicon.2015.06.012
  94. Garcia, Juliana; Costa, Vera M.; Baptista, Paula; Bastos, Maria de Lourdes; Carvalho, Félix. "Quantification of alpha-amanitin in biological samples by HPLC using simultaneous UV- diode array and electrochemical detection". Journal of Chromatography B 997 (2015): 85-95. http://dx.doi.org/10.1016/j.jchromb.2015.06.001.
    10.1016/j.jchromb.2015.06.001
  95. Dores-Sousa, José Luís; Duarte, José Alberto; Seabra, Vítor; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa. "The age factor for mitoxantrone's cardiotoxicity: Multiple doses render the adult mouse heart more susceptible to injury". Toxicology 329 (2015): 106-119. http://dx.doi.org/10.1016/j.tox.2015.01.006.
    Published • 10.1016/j.tox.2015.01.006
  96. Teixeira-Gomes, Armanda; Costa, Vera Marisa; Feio-Azevedo, Rita; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo. "The neurotoxicity of amphetamines during the adolescent period". International Journal of Developmental Neuroscience 41 1 (2014): 44-62. http://dx.doi.org/10.1016/j.ijdevneu.2014.12.001.
    10.1016/j.ijdevneu.2014.12.001
  97. Nogueira, T.B.; da Costa Araújo, S.; Carvalho, F.; Pereira, F.C.; Fernandes, E.; Bastos, M.L.; Costa, V.M.; Capela, J.P.. "Modeling chronic brain exposure to amphetamines using primary rat neuronal cortical cultures". Neuroscience 277 (2014): 417-434. http://dx.doi.org/10.1016/j.neuroscience.2014.07.009.
    10.1016/j.neuroscience.2014.07.009
  98. Soares, Ana S.; Costa, Vera M.; Diniz, Carmen; Fresco, Paula. "The combination of Cl-IB-MECA with paclitaxel: a new anti-metastatic therapeutic strategy for melanoma". Cancer Chemotherapy and Pharmacology 74 4 (2014): 847-860. http://dx.doi.org/10.1007/s00280-014-2557-y.
    10.1007/s00280-014-2557-y
  99. Soares, Ana Sofia; Costa, Vera Marisa; Diniz, Carmen; Fresco, Paula. "Inosine Strongly Enhances Proliferation of Human C32 Melanoma Cells through PLC-PKC-MEK1/2-ERK1/2 and PI3K Pathways". Basic & Clinical Pharmacology & Toxicology 116 1 (2014): 25-36. http://dx.doi.org/10.1111/bcpt.12280.
    10.1111/bcpt.12280
  100. Soares, Ana S.; Costa, Vera M.; Diniz, Carmen; Fresco, Paula. "Combination of Cl-IB-MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR-dependent autophagy and mitotic catastrophe on human melanoma cells". Journal of Cancer Research and Clinical Oncology 140 6 (2014): 921-935. http://dx.doi.org/10.1007/s00432-014-1645-z.
    10.1007/s00432-014-1645-z
  101. Feio-Azevedo, Rita; Costa, Vera Marisa; Ferreira, Luisa Pinto; Branco, Paula Serio; Pereira, Frederico Costa; Bastos, Maria de Lourdes; Carvalho, Felix; Capela, Joao Paulo. "Amphetamine and its metabolite 4-hydroxyamphetamine neurotoxicity in differentiated SH-SY5Y neurons". Toxicology Letters 229 (2014): S241-S241. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000341134000754&KeyUID=WOS:000341134000754.
    10.1016/j.toxlet.2014.06.805
  102. Reis-Mendes, Ana; Sousa, Emelia; Remiao, Fernando; Carvalho, Felix; Bastos, Maria Lourdes; Costa, Vera Marisa. "At pharmacology relevant concentrations, mitoxantrone causes time- and concentration-dependent toxicity in H9c2 differentiated cells with autophagy involvement". Toxicology Letters 229 (2014): S246-S246. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000341134000768&KeyUID=WOS:000341134000768.
    10.1016/j.toxlet.2014.06.819
  103. Rossato, Luciana G.; Costa, Vera M.; Dallegrave, Eliane; Arbo, Marcelo; Dinis-Oliveira, Ricardo J.; Santos-Silva, Alice; Duarte, José A.; et al. "Cumulative Mitoxantrone-Induced Haematological and Hepatic Adverse Effects in a SubchronicIn vivoStudy". Basic & Clinical Pharmacology & Toxicology 114 3 (2013): 254-262. http://dx.doi.org/10.1111/bcpt.12143.
    10.1111/bcpt.12143
  104. Rossato, Luciana Grazziotin; Costa, Vera Marisa; Dallegrave, Eliane; Arbo, Marcelo; Silva, Renata; Ferreira, Rita; Amado, Francisco; et al. "Mitochondrial Cumulative Damage Induced by Mitoxantrone: Late Onset Cardiac Energetic Impairment". Cardiovascular Toxicology 14 1 (2013): 30-40. http://dx.doi.org/10.1007/s12012-013-9230-2.
    Published • 10.1007/s12012-013-9230-2
  105. Soares, Ana S.; Costa, Vera M.; Diniz, Carmen; Fresco, Paula. "Potentiation of cytotoxicity of paclitaxel in combination with Cl-IB-MECA in human C32 metastatic melanoma cells: A new possible therapeutic strategy for melanoma". Biomedicine & Pharmacotherapy 67 8 (2013): 777-789. http://dx.doi.org/10.1016/j.biopha.2013.08.003.
    10.1016/j.biopha.2013.08.003
  106. Rossato, Luciana Grazziotin; Costa, Vera Marisa; Vilas-Boas, Vânia; de Lourdes Bastos, Maria; Rolo, Anabela; Palmeira, Carlos; Remião, Fernando. "Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event". Cardiovascular Toxicology 13 4 (2013): 413-425. http://dx.doi.org/10.1007/s12012-013-9224-0.
    10.1007/s12012-013-9224-0
  107. Costa, Vera Marisa; Carvalho, Félix; Duarte, José Alberto; Bastos, Maria de Lourdes; Remião, Fernando. "The Heart As a Target for Xenobiotic Toxicity: The Cardiac Susceptibility to Oxidative Stress". Chemical Research in Toxicology 26 9 (2013): 1285-1311. http://dx.doi.org/10.1021/tx400130v.
    10.1021/tx400130v
  108. Freitas, Marisa; Costa, Vera M.; Ribeiro, Daniela; Couto, Diana; Porto, Graça; Carvalho, Félix; Fernandes, Eduarda. "Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils". Toxicology Letters 219 2 (2013): 170-177. http://dx.doi.org/10.1016/j.toxlet.2013.03.007.
    10.1016/j.toxlet.2013.03.007
  109. Rossato, Luciana Grazziotin; Costa, Vera Marisa; de Pinho, Paula Guedes; Arbo, Marcelo Dutra; de Freitas, Victor; Vilain, Laure; de Lourdes Bastos, Maria; Palmeira, Carlos; Remião, Fernando. "The metabolic profile of mitoxantrone and its relation with mitoxantrone-induced cardiotoxicity". Archives of Toxicology 87 10 (2013): 1809-1820. http://dx.doi.org/10.1007/s00204-013-1040-6.
    Published • 10.1007/s00204-013-1040-6
  110. Capela, João Paulo; da Costa Araújo, Silvana; Costa, Vera Marisa; Ruscher, Karsten; Fernandes, Eduarda; Bastos, Maria de Lourdes; Dirnagl, Ulrich; Meisel, Andreas; Carvalho, Félix. "The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons". NeuroToxicology 34 (2013): 254-263. http://dx.doi.org/10.1016/j.neuro.2012.09.005.
    10.1016/j.neuro.2012.09.005
  111. Ferreira, P.S.; Nogueira, T.B.; Costa, V.M.; Branco, P.S.; Ferreira, L.M.; Fernandes, E.; Bastos, M.L.; et al. "Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells". Toxicology Letters 216 2-3 (2013): 159-170. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871546317&partnerID=MN8TOARS.
    10.1016/j.toxlet.2012.11.015
  112. Carvalho, Márcia; Carmo, Helena; Costa, Vera Marisa; Capela, João Paulo; Pontes, Helena; Remião, Fernando; Carvalho, Félix; Bastos, Maria de Lourdes. "Toxicity of amphetamines: an update". Archives of Toxicology 86 8 (2012): 1167-1231. http://dx.doi.org/10.1007/s00204-012-0815-5.
    Published • 10.1007/s00204-012-0815-5
  113. M. Costa, V.; Carvalho, F.; L. Bastos, M.; A. Carvalho, R.; Carvalho, M.; Remiao, F.. "Contribution of Catecholamine Reactive Intermediates and Oxidative Stress to the Pathologic Features of Heart Diseases". Current Medicinal Chemistry 18 15 (2011): 2272-2314. http://dx.doi.org/10.2174/092986711795656081.
    10.2174/092986711795656081
  114. Rossato, Luciana Grazziotin; Costa, Vera Marisa; Limberger, Renata Pereira; Bastos, Maria de Lourdes; Remião, Fernando. "Synephrine: From trace concentrations to massive consumption in weight-loss". Food and Chemical Toxicology 49 1 (2011): 8-16. http://dx.doi.org/10.1016/j.fct.2010.11.007.
    10.1016/j.fct.2010.11.007
  115. Costa, Vera M; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa; Carvalho, Félix. "Género masculino vs. feminino: factor relevante para as respostas farmacológicas e efeitos adversos de fármacos?". Acta Farmacêutica Portuguesa 1 1 (2011): 55-64. http://www.actafarmaceuticaportuguesa.com/index.php/afp/article/view/32.
    Published
  116. Rossato, Luciana Grazziotin; Costa, Vera Marisa; de Pinho, Paula Guedes; Carvalho, Félix; de Lourdes Bastos, Maria; Remião, Fernando. "Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes". Archives of Toxicology 85 8 (2010): 929-939. http://dx.doi.org/10.1007/s00204-010-0630-9.
    10.1007/s00204-010-0630-9
  117. Rossato, Luciana Grazziotin; de Pinho, Paula Guedes; Silva, Renata; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Costa, Vera Marisa; Remião, Fernando. "Development and validation of a GC/IT-MS method for simultaneous quantitation of para and meta-synephrine in biological samples". Journal of Pharmaceutical and Biomedical Analysis 52 5 (2010): 721-726. http://dx.doi.org/10.1016/j.jpba.2010.02.022.
    10.1016/j.jpba.2010.02.022
  118. Oliveira, Susana J.; Pinto, Jorge P.; Picarote, Gonçalo; Costa, Vera M.; Carvalho, Félix; Rangel, Maria; de Sousa, Maria; de Almeida, Sérgio F.. "ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity". PLoS ONE 4 8 (2009): e6618. http://dx.doi.org/10.1371/journal.pone.0006618.
    10.1371/journal.pone.0006618
  119. Costa, Vera Marisa; Silva, Renata; Tavares, Ludgero Canário; Vitorino, Rui; Amado, Francisco; Carvalho, Félix; Bastos, Maria de Lourdes; et al. "Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes". Toxicology 260 1-3 (2009): 84-96. http://dx.doi.org/10.1016/j.tox.2009.03.012.
    10.1016/j.tox.2009.03.012
  120. Costa, Vera Marisa; Silva, Renata; Ferreira, Rita; Amado, Francisco; Carvalho, Félix; de Lourdes Bastos, Maria; Carvalho, Rui Albuquerque; Carvalho, Márcia; Remião, Fernando. "Adrenaline in pro-oxidant conditions elicits intracellular survival pathways in isolated rat cardiomyocytes". Toxicology 257 1-2 (2009): 70-79. http://dx.doi.org/10.1016/j.tox.2008.12.010.
    10.1016/j.tox.2008.12.010
  121. Costa, Vera Marisa; Ferreira, Lui´sa Maria; Branco, Paula Se´rio; Carvalho, Fe´lix; Bastos, Maria Lourdes; Carvalho, Rui Albuquerque; Carvalho, Ma´rcia; Remia~o, Fernando. "Cross-Functioning between the Extraneuronal Monoamine Transporter and Multidrug Resistance Protein 1 in the Uptake of Adrenaline and Export of 5-(Glutathion-S-yl)adrenaline in Rat Cardiomyocytes". Chemical Research in Toxicology 22 1 (2009): 129-135. http://dx.doi.org/10.1021/tx8002577.
    10.1021/tx8002577
  122. Costa, Vera Marisa; Silva, Renata; Ferreira, Luísa Maria; Branco, Paula Sério; Carvalho, Félix; Bastos, Maria Lourdes; Carvalho, Rui Albuquerque; Carvalho, Márcia; Remião, Fernando. "Oxidation Process of Adrenaline in Freshly Isolated Rat Cardiomyocytes: Formation of Adrenochrome, Quinoproteins, and GSH Adduct". Chemical Research in Toxicology 20 8 (2007): 1183-1191. http://dx.doi.org/10.1021/tx7000916.
    10.1021/tx7000916
  123. Silva, R.; Boldt, S.; Costa, V.M.; Carmo, H.; Carvalho, M.; Carvalho, F.; Bastos, M. de L.; Lemos-Amado, F.; Remião, F.. "Evaluation of GSH adducts of adrenaline in biological samples". Biomedical Chromatography 21 7 (2007): 670-679. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447504376&partnerID=MN8TOARS.
    10.1002/bmc.796
  124. Costa, Vera; Carvalho, Marcia; Carvalho, Felix; Bastos, Maria Lourdes; Carvalho, Rui; Remiao, Fernando. "Effect of adrenaline and oxygen free radicals on calcium tolerant cardiomyocytes: Formation of glutathione adducts". Toxicology Letters 164 (2006): S130-S131. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000240407200267&KeyUID=WOS:000240407200267.
    10.1016/j.toxlet.2006.06.274
Journal issue
  1. Costa, Vera M; Carvalho, Félix. "Pharmacology of Cardiovascular Disease". Biomolecules (2023): https://www.mdpi.com/journal/biomolecules/special_issues/Pharmacology-Cardiovascular.
    In press • Invited editor
  2. Capela, João Paulo; Costa, Vera Marisa. "Pharmacology and Toxicology of Amphetamine Type Stimulants". Future Pharmacolgy (2023):
    Accepted • Invited editor
  3. Costa, Vera; Battal, Dilek ; Ziulkoski, Ana Luiza ; Amos, Samson ; Moon, Yuseok ; Venosa, Alessandro ; Feliu, Neus; et al. "Emerging Talents in Toxicology: Clinical Toxicology". Frontiers in Toxicology (2023):
    Submitted • Invited editor
  4. Costa, Vera M. "Current Frames on Cardiotoxicology of New and Old Anticancer Drugs". Pharmaceuticals (2023):
    Submitted • Invited editor
Thesis / Dissertation
  1. Costa, Vera Marisa Freitas. "Role of catecholamines and reactive oxygen species in the mechanism of oxidative stress-induced heart disease:in vitro studies using fresly isolated rat cardiomyocytes". PhD, 2011. http://hdl.handle.net/10216/20812.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/05/03 Exploring Proline's Puckering Effect on the Allosteric Modulatory Activity of Melanostatin Neuropeptide Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto 2023
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2023/04/28 The influence of glutathione pathway modulators on the cytotoxicity of sunitinib, doxorubicin and bortezomib in AC16 cardiac cells. This oral communication was selected for the Scientific Committee of the event. II TOXRUN International Congress;
TOXRUN – Toxicology Research Unit, CESPU (Porto, Portugal)
2023/04/27 Cardiac mitochondrial dynamics, autophagy and regeneration are stirred by doxorubicin in old CD-1 mice. This oral communication was selected for the Scientific Committee of the event. II TOXRUN International Congress
TOXRUN – Toxicology Research Unit, CESPU (Porto, Portugal)
2023/02 Cardiac metabolism, proteolysis and regeneration are disturbed by mitoxantrone in old CD-1 mice. 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology (SPF 2023)
Faculty of Medicine of University of Coimbra (Coimbra, Portugal)
2022/12/07 Cardio-oncology: for old or new drugs, the problem (cardiotoxicity) remains after cancer treatment Cardio-oncology: from adverse outcome pathways to treatments to mitigate cardiotoxicity of anticancer therapies’
MDPI (Switzerland)
2022/11 In the heart of cardio-oncology: the targets and biomarkers of anticancer drugs cardiotoxicity 8th International Electronic Conference on Medicinal Chemistry
MDPI (Online, Switzerland)
2022/09/08 Cardio-oncology: something old, something new, something bowered and something blue ystems in Toxicology and Pharmacology – Current challenges
(Online)
2022/09/04 The dark side of anticancer therapy: in the heart of cardio-oncology SPF Seminars
Sociedade Portuguesa de Farmacologia (Online, Portugal)
2022/04 Molecular alterations underlying doxorubicin’s chronic cardiotoxicity in a mouse model. This oral communication was selected for the Scientific Committee of the event I International Congress of TOXRUN, V Congress of Portuguese Association of Forensic Sciences, XIV Scientific Journeys of Sciences of University Institute of Health Sciences
TOXRUN – Toxicology Research Unit, CESPU (Porto, Portugal)
2020/11 Evaluation of doxorubicin and mitoxantrone neurotoxicity in CD-1 mice 2ª Edição do Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto (FFUP)
Faculdade de Farmácia da Universidade do Porto (FFUP) (Porto, Portugal)
2019/11/27 The heart of the matter: cardiotoxicity mechanisms in new and old anticancer drugs no 8º ciclo de palestras públicas de divulgação científica por professores na Faculdade de Farmácia da Universidade do Porto e Instituto de Biomédicas Abel Salazar (ICBAS)
Faculdade de Farmácia da Universidade do Porto e Instituto de Biomédicas Abel Salazar (ICBAS) (Porto, Portugal)
2017/11/01 Old Pharmaceuticals with New Applications: the Case Studies of Lucanthone and Mitoxantrone 3rd International Electronic Conference on Medicinal Chemistry
MDPI
2016/11 Combater o cancro e envenenar o coração: a dura realidade da terapia anticancerígena 5º Ciclo de palestras públicas de divulgação científica por professores
Faculdade de Farmácia da Universidade do Porto e Instituto de Biomédicas Abel Salazar (Porto, Portugal)
2016/07/10 É o metabolismo dos fármacos anticancerígenos um factor crucial para o desenvolvimento de cardiotoxicidade? Serão os anticancerígenos causadores de envelhecimento cardíaco? 1º Encontro Anual do Departamento de Ciências Biológicas
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2014/11 Drogas no local de trabalho IX Congresso da Associação de Estudantes / Toxicomanías e drogas de abuso
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2012/11 Estudo de caso: Mitoxantrona - reações adversas VII Congresso da Associação de Estudantes/ Reações adversas e interações medicamentosas: O outro lado Farmacoterapia’
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2012/09 In vitro models of cardiotoxicity European “Advanced Course in Toxicology”
European Toxicologist Association - Eurotox and Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2012/07 Ecstasy' and amphetamine neurotoxicity to cultured rat cortical neurons in a continuous exposure model 6th European Congress on Pharmacology EPHAR 2012
European Society of Pharmacologists (Granada, Spain)
2012/02 Riscos da exposição a resíduos Resíduos em Portugal
Escola Superior Agrária de Coimbra (Coimbra, Portugal)
2011/08 Therapeutic concentrations of mitoxantrone elicit cytotoxic effects on H9c2 cells 47th Congress of the European Societies of Toxicology
(Paris, France)
2011/05 Understanding the role of NRF2/ARE signalling in the cellular defence against iron toxicity International BioIron Society Biennial World Meeting (IBIS 2011 - Vancouver)
BioIron Society Biennial World Society (Vancouver, Canada)
2011/04 Avaliação in vitro da potencial cardiotoxicidade dos compostos. Exemplos de estudos em cardiomiócitos isolados Avaliação in vitro da segurança dos compostos
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2009/09 Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes 46th Congress of European Societies of Toxicology
(Dresden, Germany)
2009/05 Biomarcadores tumorais Workshop Neoplasia
Instituto Superior de Ciências da Saúde do Norte (Paredes, Portugal)
2007/12 Time dependent activation of transcription factors in freshly isolated rat cardiomyocytes under stimulation by adrenaline and reactive oxygen species. XXXVIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXV Reunião de Farmacologia Clínica
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2007/12 Mediated membrane transport in isolated cardiac myocytes via catecholamine uptake 2 and 5-(glutathion-S-yl)adrenaline efllux by MRP1 XXXVIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXV Reunião de Farmacologia Clínica
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2007/12 Oxidation of adrenaline in cardiomyocytes: formation of adrenochrome, quinoproteins, and GSH-adducts XXXVII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIV Reunião de Farmacologia Clínica
Sociedade Portuguesa de Farmacologia (Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/01/01 - Current Synthesis and Biological Evaluation of Alicyclic Melanostatin and Glypromate Peptidomimetics with Application in Neurodegenerative Diseases
Co-supervisor
 PhD Sustentable Chemistry (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2023/01/01 - Current Amphetamine (AMPH) and D,L-threo-Methylphenidate (MPH) ability to synaptogenesis in an attention-deficit/hyperactivity disorder (ADHD) rat model
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2023/01 - Current A toxicological in vitro comparative study of alpha-PVP, 3,4-dimethylmethcatinone (3,4-DMMC) and mephedrone (4-MMC) in human cardiac AC16 cells
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Faculty of Pharmacy of University of Porto, Portugal
2023/01 - Current The study of the cardiotoxicity of anthracyclines anticancer drugs: a comparative metabolomics study
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Faculty of Pharmacy of University of Porto, Portugal
2023/01 - Current The neurotoxic mechanisms of new and old anticancer drugs on astrocytes: an in vitro study in C6 cells
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Faculty of Pharmacy University of Porto, Portugal
2021/11/01 - Current The neurotoxic mechanisms of new and old anticancer drugs: from in vitro to in vivo studies
Supervisor
 Doutoramento em Ciências Farmacêuticas (PhD)
Faculty of Pharmacy of University of Porto, Portugal
2021/03/01 - Current Unveiling the neurotoxic mechanisms of anticancer drugs: combining insights from neuronal and glial contributions to chemobrain
Supervisor
 Pharmaceuticals Sciences (PhD)
REQUIMTE, Portugal

Faculty of Pharmacy University of Porto, Portugal
2020/01/01 - Current NeuroPro: Peptide Conjugates for Neurodegenerative Diseases using Constrained Prolines
Co-supervisor
 Química Sustentável (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2019/07/01 - Current Can early biomarkers of aging predict the cardiotoxicity induced by doxorubicin and mitoxantrone? An Omics approach on early biomarkers of aging
Supervisor
 PhD in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/02/01 - 2024/04/11 Inflammation and disruption of redox homeostasis (but not metabolism) significantly contribute to the cardiotoxic effects of mitoxantrone and doxorubicin: findings from in vitro and in vivo studies conducted on differently aged mice
Supervisor
 PhD in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/09/01 - 2023/11/22 Synthesis and Biological Evaluation of Melanostatin Aza-Peptides for Application in Parkinson's Disease
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/01 - 2023/11/22 Synthesis, Pharmacological, and Toxicological Evaluation of Carbamate-Based Melanostatin Analogues with Potential Anti-Parkinson Activity
Co-supervisor
 Química Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/09/01 - 2023/11/16 Nrf2 modulators as pharmacological strategies to tackle the cardiotoxicity of anti-cancer drugs: a cardio-oncology in vitro study in human cardiac AC16 cells
Supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/09/01 - 2022/12/06 The study of the cardiotoxicity of targeted anticancer drugs: an in vitro metabolomics study
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Faculty of Pharmacy of University of Porto, Portugal
2019/09/01 - 2022/12/06 Neuroprotection of Amphetamine and Methylphenidate psychostimulants against dopaminergic neurotoxins in an in vitro Parkinson model
Co-supervisor
 Mestrado em Toxicologia Analítica Clínica e Forense (Master)
Faculty of Pharmacy University of Porto, Portugal
2020/09/01 - 2021/10/14 Chemobrain: the neurotoxic mechanisms of doxorubicin and mitoxantrone
Supervisor
 Master in Biochemistry (Master)
Universidade de Aveiro Departamento de Química, Portugal
2015/02/01 - 2021/06/21 Neurotoxicity of synthethic cathinones
Co-supervisor
 Ph in Experimental and Clinical Pharmacology and Toxicology (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2019/09/01 - 2020/12/11 Biomarkers of heart damage caused by cyclophosphamide: a proteomic and metabolomic approach in AC16 human cardiomyocyte cells and CD-1 mice
Supervisor
 Master of Biochemistry (Master)
Faculty of Sciences University of Porto, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/09/30 - 2020/12/09 The neurotoxicity of doxorubicin and mitoxantrone in different aged mice: in vivo studies of chemobrain
Supervisor
 MSc in Analytical, Clinical and Forensic Toxicology (Master)
Faculty of Pharmacy University of Porto, Portugal
2017 - 2019 In vitro evaluation of antidotes for Amanita Phalloides intoxications
Co-supervisor
 Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 The influence of age on the toxicity induced by mitoxantrone: in vivo studies with mice
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2018 Studies towards the synthesis of metabolites of mitoxantrone
Co-supervisor
 Química Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2017 Methylphenidate effects after one-week exposure in adolescente rats
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09/01 - 2016/12/06 Comparação da citotoxicidade de fármacos anticancerígenos e da sua mistura em células H9c2 diferenciadas
Supervisor
 Master in Toxicology and Ecotoxicology
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015 Brain and Peripheral Organ Toxicity of "Ecstasy" in Adolescent Rats in Human Relevant Doses
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2015 Discovery of an effective antidote for Amanita Phalloides poisoning
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2013/09/05 - 2014/11/14 The Synthesis and in Vitro Toxicological Evaluation of the Mitoxantrone Naphthoquinoxaline Metabolite: A Comparative Study with the Parent Drug
Supervisor
 Master in Clinic, Forensic and Analytic Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2014/01 The cardiotoxicity of mitoxantrone: a mechanistic approach using in vitro and in vivo models.
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2013 Toxicity of the antitumor drug mitoxantrone in pediatric and adult mice
Supervisor
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2009 - 2010/07/10 Estudo do transporte celular da sinefrina e da sua interacção com a glutationa em suspensões de cardiomiócitos isolados de rato adulto
Co-supervisor
 Master in Analytical, Forensic and Clinical Toxicology (Master)
Faculty of Pharmacy of University of Porto, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/12/07 - Current Cardio-oncology: from adverse outcome pathways to cardiotoxicity mitigation, online event (https://pharmaceuticals-1.sciforum.net/) (2022/12/07)
Symposium (Co-organisor)
 MDPI AG, Switzerland
2023/07/05 - 2023/07/07 Joint Session of i4HB and CIMAR - Encontro Ciência 2023, Aveiro (2023/07/07 - 2023/07/07)
Conference (Member of the Organising Committee)
 Fundação para a Ciência e a Tecnologia, Portugal
2023/01/16 - 2023/01/23 Continuous Training Unit (UFC) within the scope of the Multidisciplinary Training Program of the U. Porto - Impulse Adults, funded by the Recovery and Resilience Plan (PRR) (2023/01/16 - 2023/01/23)
Workshop (Co-organisor)
 Faculty of Medicine of University of Porto, Portugal
2019/03/06 - 2019/03/06 Workshop on animal models of disease (2019/03/06 - 2019/03/06)
Workshop (Member of the Scientific Committee)
 Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2019/02/06 - 2019/02/08 XLIX Meeting of the Portuguese Pharmacology Society, XXXVII Meeting of Clinical Pharmacology, XVIII Meeting of Toxicology (2019/02/06 - 2019/02/08)
Meeting (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/10 - 2018/07/10 Manhã do Departamento de Ciências Biológicas was a interlaboratory meeting to discusse new findings and establish (2018/07/10 - 2018/07/10)
Seminar (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2017/10/23 - 2017/10/27 TOX-OER (Learning Toxicology through Open Educational Resources) is a project, which aims to design and develop an international Massive Open Online Course (MOOC) on Toxicology. Intensive Learners Meeting Pharmaco/Toxicokinetics was held in modules in Toxicology Laboratory in Faculty of Pharmacy (2017/10/23 - 2017/10/27)
Workshop (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2015/09/13 - 2015/09/16 Organization of the International congress: 51st European Congress of Toxicology Societies (2015/09/13 - 2015/09/16)
Congress (Other)
 Federation of European Toxicologists & European Societies of Toxicology, Switzerland

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/11/28 Influence of antiparasitic benzimidazole derivatives in the cytoskeletal organization of metastatic breast cancer cells
(Thesis) Main arguer
 Patrícia Isabel Pinto Nogueira (Master)
Faculty of Pharmacy University of Porto, Portugal
2023/10/09 Investigating the dynamics of proliferative cardiomyocytes: validation of an in vitro model
(Thesis) Arguer
 Rodrigo Vieira Teixeira de Sousa Santos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2023/09/26 Flavonoides como moduladores da diabetes tipo 2 através da inibição das enzimas a-amilase e alpha-glucosidase
(Thesis) Main arguer
 Edite Ferreira Pinto (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2022/12/06 The study of the cardiotoxicity of targeted anticancer drugs: an in vitro metabolomics study
Supervisor
 Tânia Gomes (Master)
Faculty of Pharmacy of University of Porto, Portugal
2021/10/14 Chemobrain: the neurotoxic mechanisms of doxorubicin and mitoxantrone
Supervisor
 Mariana Ferreira (Master)
Universidade de Aveiro Departamento de Química, Portugal
2021/07/23 Insights on the molecular targets of anticancer drugs-induced cardiotoxicity: a systematic review based on proteomics findings
Supervisor
 Sofia Brandão (Other)
Faculty of Pharmacy University of Porto, Portugal
2021/06/21 Nano-based drug delivery systems used as vehicles of polyphenols for diabetes mellitus treatment
(Thesis) Main arguer
 Adelaide Patrícia Teles de Sousa intitulado (Other)
Faculty of Pharmacy University of Porto, Portugal
2020/12/11 The neurotoxicity of doxorubicin and mitoxantrone: chemobrain studies using infant, adult, and old mice
Supervisor
 Ana Rita Dias Carvalho (Master)
Faculty of Pharmacy of University of Porto, Portugal
2020/12/09 Biomarkers of heart damage caused by cyclophosphamide: a metabolomic approach in AC16 human cardiomyocytes
Supervisor
 Flávio Dionísio da Costa (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Faculty of Sciences University of Porto, Portugal
2020/06/21 PRO-INFLAMMATORY EFFECTS OF SILVER NANOPARTICLES IN THE INTESTINE
(Thesis) Arguer
 Adelaide Patrícia Teles de Sousa (Other)
Faculty of Pharmacy University of Porto, Portugal
2020/06/08 Pro-inflammatory effects of silver nanoparticles in the intestine
(Thesis) Main arguer
 Sónia Aguiar da Rocha (Other)
Faculty of Pharmacy University of Porto, Portugal
2019/07/09 The importance of fertility preservation in cancer patients treated with ciclophosphamide
(Thesis) Main arguer
 Mariana Castelõa (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/11/14 In vitro evaluation of antidotes for Amanita phalloides intoxications
Supervisor
 Daniela Rodrigues. (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/11/12 The influence of age on the toxicity induced by mitoxantrone: in vivo studies with mice
Supervisor
 Rita Alexandra Guedes (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/09/18 Main metabolites of 5-fluorouracil + adriamycin/doxorubicin + cyclophosphamide (FAC) are not major contributors to FAC toxicity in H9c2 cardiac differentiated cells
Supervisor
 Ana Filipa Reis Mendes (Other)
Faculty of Pharmacy University of Porto, Portugal
2018/07/12 Effects of Phytocannabinoids in human endometrium
(Thesis) Main arguer
 Patrícia Manuela Fonseca Malheiro (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/10 The influence of doxorubicin and mitoxantrone on the redox status of the brain of differently aged mice
Supervisor
 Ana Rita Dias de Carvalho (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/07/06 A cytotoxicity study of pixantrone in non-differentiated H9c2 cells
Supervisor
 Marisa Alexandra Pinto Alves (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/02/16 Estratégias farmacológicas para evitar a neurotoxicidade da doxorrubicina e da mitoxantrona, em células SH-SY5Y
Supervisor
 Rita Pinho (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/12/06 Comparação da citotoxicidade de fármacos anticancerígenos e sua mistura em células H9c2 diferenciadas
Supervisor
 Maria Rosário OLiveira (Master)
Universidade de Aveiro, Portugal
2016/04/04 Estudo da citotoxicidade da doxorrubicina e da mitoxantrona em células SH-SY5Y
Supervisor
 Ana Daniela Almeida (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/10/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Andrea de Fátima Tavares Rodrigues (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Luís Miguel Alves Carvalho dos Santos (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Luís Miguel Ferreira de Sousa (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Maria Mafalda Jordão da Cunha Abreu (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Marina Manuela Dias Mesquita (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Patrícia Borges Fernandes (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Carlos Pedro Mendes (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Diogo Maximiano Barros Figueiredo Ramos (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Gonçalo Augusto Pessoa Jorge Mendes (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 João António Caldas Amorim (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 José Eduardo Monteiro Corujo Moreira Carneiro (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Raquel Sofia Ferreira Sanches (Other)
Faculty of Medicine of University of Porto, Portugal
2015/10/05 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Sara Isabel Almeida de Magalhães (Other)
Faculty of Medicine of University of Porto, Portugal
2015/09/09 XVI CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Solange Teles Braga (Other)
Faculty of Medicine of University of Porto, Portugal
2015/07/23 Avaliação da toxicidade da mitoxantrona em modelo de células neuronais SH-SY5Y
Supervisor
 Verónica Correia (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/07/21 Efeitos do 9tetrahidrocanabinol em células do estroma do endométrio humano
(Thesis) Main arguer
 José Carlos Ribeiro (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/11/14 The synthesis and in vitro toxicological evaluation of the mitoxantrone naphthoquinoxaline metabolite: A comparative study with the parent drug
Supervisor
 Ana Filipa dos Reis Mendes (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/10/28 Efeito de nanopartículas de prata em neutrófilos humanos
(Thesis) Main arguer
 Tânia Sofia Couto Soares (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013/12/02 Toxicity of the antitumour drug mitoxantrone in pediatric and adult mice
Supervisor
 José Luis Dores Sousa (Master)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/11/11 Exposição ocupacional na manipulação de citotóxicos
(Thesis) Main arguer
 Sara Afonso Mendes (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2011/09/28 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Cláudia Sofia Gomes de Carvalho (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/28 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 João Nelson de Magalhães Teixeira (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/28 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 João Nelson de Magalhães Teixeira (Other)
Universidade do Porto Faculdade de Medicina, Portugal
2011/09/28 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Liliana Rego Soares (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/28 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Juan Jesús Albaladejo Roca (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/28 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Pablo Alija Mendaña (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/26 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Adriana Ferreira da Costa (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/26 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Alcina Maria Barreto Ascenção Azevedo (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/11 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Ana Cristina Mendes Moreira de Aguilar Ferreira (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/11 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Ana Micaela da Fonseca Marinho Vaz Soares (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/11 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 André Fernandes Pinto (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/11 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Angelina de Deus Oliveira Mendes (Other)
Faculty of Medicine of University of Porto, Portugal
2011/09/11 XIV CURSO DE PÓS-GRADUAÇÃO EM MEDICINA DO TRABALHO - Final Report Evaluation
(Thesis) Arguer
 Daniela Cristina Castro Xará (Other)
Faculty of Medicine of University of Porto, Portugal
2010/10/29 Uso de Benzodiazepinas em Idosos
(Thesis) Main arguer
 João António de Oliveira Costa (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2010/07/28 A sinefrina e o seu potencial cardiotóxico
Supervisor
 Luciana Rossato (Other)
Faculty of Pharmacy University of Porto, Portugal
2010/07/09 Estudo do transporte celular da sinefrina e da sua interacção com a glutationa em suspensão de cardiomiócitos isolados de rato adulto
Supervisor
 Luciana Rossato Grazottin (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2023/10/23 - Current Archives of Toxicology Springer
2023/10/21 - Current Biochemical Pharmacology Elsevier
2023/09/25 - Current Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Elsevier
2023/01/23 - Current Nature Communications Nature
2019/01/10 - Current Food and Chemical Toxicology Elsevier
2018/08/28 - Current Cardiovascular Toxicology (15590259) Springer
2018/06/22 - Current Human & Experimental Toxicology SAGE
2017/09/14 - Current Toxicology and Applied Pharmacology Elsevier
2017/02/25 - Current Free Radical Biology and Medicine Elsevier
2010/07/27 - Current Toxicology Elsevier
2018/01 - 2022/07/27 Food and Chemical Toxicology Elsevier
2021/01/01 - 2021/12/15 Biomolecules (ISSN 2218-273X) MDPI

Association member

Society Organization name Role
2007 - Current Sociedade Portuguesa de Farmacologia Member
2004 - Current Ordem dos Farmacêuticos Member of The Portuguese College of Pharmacists

Committee member

Activity description
Role 		Institution / Organization
2023/03/09 - Current Coordinator of Working Group (Impact) of UCIBIO Main objectives: 1.Industry and Organizations Liaison 2.Exploitation 3. Outreach & Science communication
Coordinator
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2023/03/09 - Current Executive Committee Member of UCIBIO - Porto
Member
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2023/03 - Current Coordination Committee Member of UCIBIO
Member
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2022 - Current Vice-coordinator of the Stakeholders Group of National Cancer HUB (Survivors Group), an organization held by Agência de Investigação Clínica e Inovação Biomédica and Direção Geral da Saúde.
President / Vice-president
 Agência de Investigação Clínica e Inovação Biomédica, Portugal

Direção Geral da Saúde, Portugal

Consulting

Activity description Institution / Organization
2024 - Current Mentor for the DIANA programme NATO, Belgium
2023/02 - Current Member of the 4UNCAN.eu: a European initiative to better understand cancer https://ccieurope.eu/uncan-eu-better-understand-cancer/ European Union, Belgium
2023 - Current Member of Phase 4 of a European Organisation for Research and Treatment of Cancer (EORTC) project for a survivorship questionnaire European Organisation for Research and Treatment of Cancer (EORTC) , Belgium
2022 - Current Expert for UNICAN.EU “A European initiative to UNderstand CANcer'. An initiative to better UNderstand CANcer (UNCAN.eu) is part of the implementation roadmap of two programs of the European Union (EU), Europe’s Beating Cancer Plan and the Horizon Europe Mission on Cancer. European Union, Belgium
2021/12/15 - Current External Expert Open Call OC-2021-1 of COST (Reserve List) European Cooperation in Science and Technology, Belgium
2021 - Current Foundation for Polish Science Smart Growth Operational Programme Fundacja na rzecz Nauki Polskiej, Poland
2021 - Current Consulting for scientific projects and grants for the Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania., Romania
2020/11/20 - Current Evaluation Committe Review of projects submitted to the Science Fund of the Republic of Serbia
2020 - Current Evaluation Committe Review of projects submitted to the Italian Science Ministry of Italy REPRISE (the Register of Scientific Experts set up at the MIUR), Italy
2019 - Current External Advisor for Global Burden of Disease Studies (GBD) Institute for Health Metrics and Evaluation (IHME), University of Washington, United States

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/05/22 - Current Invited lecturer at the Graduate Program of Bioexperimentação, Universidade de Passo Fundo, Brazil. Graduate Program of Bioexperimentação Universidade de Passo Fundo, Brazil

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2024/04/01 - Current Scientific evaluator on the 4th National Plan for Research, Development and Innovation for the period 2022-2027 (PNCDI IV) for the Romanian National Research Council (CNCS) e Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI)
Evaluator
 Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania., Romania Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania.
2023/12 - Current Post Doc Grants "Rita Levi Montalcini" Young Researchers Program 2021
Evaluator
 Italian Ministry for University and Research (MUR) , Italy
2023 - Current Evaluation of projects of University of Parma, Italy, in the programme 'Bando di Ateneo 2022 per la ricerca - Azione A: Progetti di ricerca di consolidamento o scouting'
Evaluator
 Università degli Studi di Parma, Italy Università degli Studi di Parma
2022 - Current UO Supporto Ricerca Nazionale e Industriale, University of Parma
Evaluator
2022 - Current Evaluation of Projects on the University of Parma, within UO Supporto Ricerca Nazionale e Industriale, University of Parma Programme. Università degli Studi di Parma, Italy Università degli Studi di Parma
2021/11/01 - Current Scientific evaluator for the Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania within PED21 Programm
Evaluator
 Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania., Romania Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania.
2021/10/12 - Current Member of the evaluation of projects for the Executive Agency for Higher Education, Research, Development and Innovation Funding (https://uefiscdi.gov.ro) under the 2021 funding call Experimental Demonstrative Project (PED2021)
Evaluator
 Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania., Romania Guvernul Romaniei Secretariatul General al Guvernului
2021/10/01 - Current Contract with Fundacja na rzecz Nauki Polskiej, Poland for Scientific Projects Evaluation
Evaluator
 Fundacja na rzecz Nauki Polskiej, Poland Fundacja na rzecz Nauki Polskiej
2021/09/01 - Current Lead reviewer in projects integrated on IDEAS Programme - Serbia
Coordinator
 Science Fund of The Republic of Serbia, Serbia Government of Serbia
2021/06/01 - Current Scientific Evaluator integrated in the IDEAS Programme - Serbia
Evaluator
 Science Fund of The Republic of Serbia, Serbia
2021/02/19 - Current Event moderator in the Cardiovascular Pharmacology Section of the XLI Annual Meeting of the Portuguese Society of Pharmacology, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
Evaluator
 University of Lisboa Faculdade Farmácia, Portugal
2021 - Current Programma per Giovani Ricercatori Rita Levi Montalcini 2019 - Pos Doc Grants
Evaluator
 Italian Ministry for University and Research (MUR) , Italy Italian Ministry for University and Research (MUR)
2021 - Current Programme 2020 PRIN of Italian Ministry for University and Research (MUR) Scientific projects on Healh Sciences
Evaluator
 Italian Ministry for University and Research (MUR) , Italy Italian Ministry for University and Research (MUR)
2020/08/01 - Current Evaluator of Scientific Projects at REPRISE (the Register of Scientific Experts set up at the Ministry of Education, University and Research MUR, Of Italy) for the following sections: Fundamental research Applied research Scientific popularization
Evaluator
 Italian National Agency for the Evaluation of the University and Research Systems
2024/04/01 - 2024/05/01 Scientific evaluator for the Austrian Science Fund (FWF).
Evaluator
 Fonds zur Förderung der wissenschaftlichen Forschung, Austria Fonds zur Förderung der wissenschaftlichen Forschung
2023/03/20 - 2023/10/31 Scientific evaluator for the Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania within the Recovery and Resilience Plan for Romania (PNRR): Investment 8. (F-PNRR-I8-2022 e F-PNRR-I8-2023 ). Development of a program to attract highly specialized human resources from abroad in research, development and innovation activities.
Evaluator
 Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania., Romania Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania.
2023/07 - 2023/10/15 Scientific Evaluator integrated in the Program for Excellent Projects of Young Researchers and Scientists in the Early Stage of Career - PROMIS 2023. (Serbia)
Evaluator
 Science Fund of The Republic of Serbia, Serbia Science Fund of The Republic of Serbia
2020/02/12 - 2020/02/14 Member of the Scientific Evaluation Committee in 13º Encontro de Investigação Jovem da Universidade do Porto, University of Porto, Porto.
Evaluator
 Universidade do Porto, Portugal
2020/02/05 - 2020/02/07 Event moderator in the Cardiovascular Pharmacology Section of the XL Annual Meeting of the Portuguese Society of Pharmacology, XXXVIII Meeting of Clinical Pharmacology and XIX Meeting of Toxicology
Other
 Sociedade Portuguesa de Farmacologia, Portugal
2020 - 2020 Programa Progetti di ricerca COVID-19 - comunicazione attività di valutazione ex ante (Avviso D.D. 562/2020) - FISR2020 Covid-19 evaluations Scientific projects under COVID
Evaluator
 Italian Ministry for University and Research (MUR) , Italy Italian Ministry for University and Research (MUR)
2019/02/06 - 2019/02/08 Event moderator in the Toxicology I Section of the XLIX Annual Meeting of the Portuguese Society of Pharmacology, XXXVII Meeting of Clinical Pharmacology and XVIII Meeting of Toxicology
Other
 Sociedade Portuguesa de Farmacologia, Portugal
2017/02/02 - 2017/02/04 Event moderator in the Toxicology II Section of the XVII Annual Meeting of the Portuguese Society of Pharmacology, XXXV Meeting of Clinical Pharmacology and XVI Meeting of Toxicology
Other
 Sociedade Portuguesa de Farmacologia, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2023/06/27 News article about research in Portugal. Full title: As histórias dos investigadores que podem ficar sememprego de um dia para o outro Observador

Journal scientific committee

Journal title (ISSN) Publisher
2023/02 - Current Helyion Elsevier
2022/03/01 - Current Frontiers in Toxicology - Clinical Toxicology Frontiers
2020/02/01 - Current Cardiovascular Toxicology (1530-7905) Springer-Verlag
2019/02/01 - Current Brazilian Journal of Pharmaceutical Sciences (1984-8250) SciELO

Mentoring / Tutoring

Topic Student name
2022/07 - Current "Verão com Ciência" 2022 Patrícia Rodrigues
2020/09/01 - Current Final Scientific Report Supervision of the experimental Project within the Biochemistry Degree, Instituto de Ciências Biomédicas Abel Salazar and Sciencies Faculty, Universidade do Porto. Ana Olívia Fernandes
2020/09/01 - Current Final Scientific Report Supervision of the experimental Project within the Biochemistry Degree, Instituto de Ciências Biomédicas Abel Salazar and Sciencies Faculty, Universidade do Porto. Maria Francisca Espincho
2022/09/01 - 2022/11/30 ERASMUS Hugo Filipe Costa Almeida
2022/07/18 - 2022/07/29 Summer Student Exchange Program (SEP) 2022 Tomasz Ciecielag
2022/07/18 - 2022/07/29 Summer Student Exchange Program (SEP) 2022 Luca Éva Uhljar
2021/03/29 - 2021/09/30 ERASMUS Mobility Elisa Milandri
2019/09/15 - 2020/01/31 ERASMUS Mobility Marina Sanchez Momblona
2019/07 - 2019/07 Summer Student Exchange Program (SEP) 2019 Andjela Ustevic
2019/07 - 2019/07 Summer Student Exchange Program (SEP) 2019 Ivana Jovanovic
2019/07 - 2019/07 Summer Student Exchange Program (SEP) 2019 Ioana Petenchiu
2018/02/28 - 2018/07/10 Final Scientific Report Biochemistry Degree Ana Rita Dias de Carvalho
2018/07 - 2018/07 Summer Student Exchange Program (SEP) 2018 Tamara Blagojenic
2018/07 - 2018/07 Summer Student Exchange Program (SEP) 2018 Vanja Visnjce
2017/02/28 - 2017/06/06 Final Scientific Report Marisa Alexandra Pinto Alves
2015/10/01 - 2017/03/04 Project I Ana Daniela Almeida
2016/10/01 - 2017/02/16 Project I Rita Pinho
2015/09/01 - 2016/01/31 International Mobility Joana Schuelter Boeing
2015/02/28 - 2015/07/25 Final Scientific Report Verónica Correia
2015/02/01 - 2015/02/28 International Mobility Maria Regenjo Vasquez
2014/02/28 - 2014/06/14 Final Degree Report Rute Português Eleutério
2012/02/01 - 2012/06/30 ERASMUS Mobility Krishnaa Pandya
2012/02/01 - 2012/06/06 ERASMUS Mobility Kulvir Grewald

Other jury / evaluation

Activity description Institution / Organization
2019/05/19 - Current Member in the selection for a candidate for a scholarship in the project "Development of antidotes for Amanita phalloides intoxications, from in silico to the intoxicated patient" (PTDC / DTP-FTO / 4973/2014 - POCI-01-0145-FEDER-016545, funded by the Science Foundation and Technology) at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. Referência ICETA 2019-39. REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2018/07/23 - Current Member and President in the selection for a candidate for a scholarship in the project "Poisoning the heart with anticancer drugs: is metabolic bioactivation or aging promotion the link to the cardiotoxicity of anticancer drugs?” (PTDC / DTP-FTO / 1489/2014 - POCI-01-0145-FEDER-016537), funded by the Science Foundation and Technology) at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2017/09/11 - Current Member in the selection for a candidate for a scholarship in the project "Development of antidotes for Amanita phalloides intoxications, from in silico to the intoxicated patient" (PTDC / DTP-FTO / 4973/2014 - POCI-01-0145-FEDER-016545, funded by the Science Foundation and Technology) at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/01/30 - Current Member of the Jury to select candidates Portuguese students from the University of Porto who would attend the Cardiopulmonary Toxicity Course in Hradec Králové (Czech Republic). Faculty of Pharmacy University of Porto, Portugal
2016/12/21 - Current Member and President in the selection for a candidate for a scholarship in the project "Poisoning the heart with anticancer drugs: is metabolic bioactivation or aging promotion the link to the cardiotoxicity of anticancer drugs?” (PTDC / DTP-FTO / 1489/2014 - POCI-01-0145-FEDER-016537), funded by the Science Foundation and Technology) at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014/04/16 - Current Member and President in the selection for a candidate for a scholarship in the project "Why is mitoxantrone a poison to the heart? Focus on mitochondria, cytoskeleton, and metabolic bioactivation mechanisms.” (EXPL/DTP-FTO/0290/2012), funded by the Science Foundation and Technology and FEDER at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2013/02 - Current Member in the selection for a candidate for a scholarship in the project "CONSEQUÊNCIAS DO CONSUMO RECREATIVO DE PSICOESTIMULANTES ANFETAMINICOS NO ENVELHECIMENTO CEREBRAL" (PTDC/SAU-FCF/102958/2008), funded by the Science Foundation and Technology and COMPETE) at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2011/07/25 - Current Member in the selection for a candidate for a scholarship in the project "CONSEQUÊNCIAS DO CONSUMO RECREATIVO DE PSICOESTIMULANTES ANFETAMINICOS NO ENVELHECIMENTO CEREBRAL" (PTDC/SAU-FCF/102958/2008), funded by the Science Foundation and Technology and COMPETE) at the ICETA-Toxicology Laboratory, Faculty of Pharmacy, University of Porto, Portugal. Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Distinctions

Award

2024 IACOBUS - PUBLICACIÓNS CIENTÍFICAS 2023-2024
Euroregião Galicia – Norte de Portugal Region, Spain
2023 Best oral Presentation in Research in Symposium of the Faculty of Pharmacy of the University of Porto 2023
Associação de Estudantes Faculdade de Farmácia Universidade do Porto, Portugal
2023 Best Poster Awarded
2022 Best Oral Presentation in Biosystems in Toxicology and Pharmacology - Current challenges
“Biosystems in Toxicology and Pharmacology – Current challenges”, Switzerland
2022 Best oral Presentation in Research Symposium of the Faculty of Pharmacy of the University of Porto 2022
Associação de Estudantes Faculdade de Farmácia Universidade do Porto, Portugal
2021 Best Poster
Organization of XII Biochemistry Day, The Biochemistry of SARS-CoV-2, Portugal
2021 3rd prize on the Best Free Communication Award.
Organization of III Jornadas Ibéricas de Toxicologia. Universidade da Beira Interior, Portugal
2020 Second prize for best oral presentation
Faculty of Pharmacy University of Porto, Portugal

Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto , Portugal
2019 Top Reviewer 2019 on Toxicology and Pharmacology
Clarivate Analytics Deutschland GmbH, Germany
2019 Top Reviewer 2019 in Cross Field
Clarivate Analytics Deutschland GmbH, Germany
2015 Pos Doc Grant
Fundação da Ciência e Tecnologia, Portugal
2015 Pedagogic award
Faculty of Pharmacy University of Porto, Portugal
2014 Best Poster
Universidade Nova de Lisboa, Portugal
2014 Highly Commended recognition Gerhard-Zbinden Young Scientist Award
Federation of European Toxicologists & European Societies of Toxicology, Switzerland
2013 Selection to be cover of Chemical Research in Toxicology
ACS Publications, United States
2009 Pos Doc Grant
Fundação da Ciência e Tecnologia, Portugal
2007 Best Poster
Portuguese Network (Procura), Portugal
2003 Merit Grant 2003 of Best Student
Universidade do Porto Faculdade de Farmácia, Portugal
1995 Best student
Rotary Club Fafe, Portugal

Other distinction

2023 Selected presentation and monetary traveling award for XXV Conference of Young SIF Pharmacologists 2023
Sociedade Portuguesa de Farmacologia, Portugal

Società Italiana di Farmacologia, Italy
2022 Rapporteur for the evaluation of Scientific International Projects of Romania
Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania., Romania
2022 Honorable mention
Students of the Academic Association of the University of Aveiro (NEQ), Portugal
2022 UCIBIO Research Unit Researchers Evaluation for 2019-2021
REQUIMTE LAQV Porto, Portugal
2021 Lead Reviewer
Science Fund of The Republic of Serbia, Serbia
2021 Short List for Best Poster EUROTOX 2021
56th Congress of The European Societies of Toxicology, Denmark
2021 Short List for Best Poster EUROTOX 2021
56th Congress of The European Societies of Toxicology, Denmark
2021 Honorable mention
Organization of XII Biochemistry Day, The Biochemistry of SARS-CoV-2, Portugal