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Francisco Miguel Piçarra Leisico. Completed the Mestrado in Molecular Biotecnology in 2014 by Universidade de Aveiro. Is Researcher in REQUIMTE Unidade de Ciências Biomoleculares Aplicadas and PhD in Structural Biochemistry (FCT Fellowship PD/BD/105737/2014 in the Molecular BioSciences PhD Program) supervised by Dr. Teresa Santos-Silva and Prof. Dr. Maria João Romão in Universidade Nova de Lisboa Departamento de Química. Published 3 articles in journals. In their professional activities interacted with 34 collaborator(s) co-authorship of scientific papers.
Identification

Personal identification

Full name
Francisco Miguel Piçarra Leisico

Citation names

  • Leisico, Francisco

Author identifiers

Ciência ID
5F1B-CEC0-4B77
ORCID iD
0000-0002-4672-4659

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Proficiency (C2) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
French Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1) Beginner (A1)
Spanish; Castilian Intermediate (B1) Beginner (A1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2015/01/05 - 2019
Ongoing
 PhD Program in Molecular Biosciences (Doutoramento)
Major in Structural Biochemistry
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
"Unraveling the enzymatic mechanism of glutamate amidation in Staphylococcus aureus peptidoglycan" (THESIS/DISSERTATION)
2014
Concluded
 Molecular Biotecnology (Mestrado)
Universidade de Aveiro, Portugal
"Discovery of pathogenicity markers in Bursaphelenchus xylophilus" (THESIS/DISSERTATION)
 18/20
Affiliation

Science

Category
Host institution 		Employer
2019/04/15 - 2019/10/15 Research Assistant (Research) European Molecular Biology Laboratory, France
European Molecular Biology Laboratory, France
2013/09/02 - 2014/12/19 Contracted Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Others

Category
Host institution 		Employer
2015/01/05 - Current PhD student REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Projects

Grant

Designation Funders
2018/10 - 2021/10 StaphOUT - Fighting Staphylococcus aureus - Peptidoglycan amidation as a new target
PTDC/BIA-MIC/31645/2017
 Fundação para a Ciência e a Tecnologia
2018 - 2021 BACTERIAL ABC-TYPE MULTITASK ENERGIZERS: ONE ATPASE FITS ALL?
PTDC/BIA-MIC/30696/2017
 Fundação para a Ciência e a Tecnologia
2016/01 - 2018/12 Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis
Provided by PTCRIS: 129378
 Fundação para a Ciência e a Tecnologia, I.P.
2016/01 - 2018/12 Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis
Provided by PTCRIS: 140528
 Fundação para a Ciência e a Tecnologia, I.P.
2012/02 - 2015/04 Nitric Oxide Synthase targeting with Re(I)/99mTc(I)-complexes containing L-Arg derivatives: A structure-activity study
Provided by PTCRIS: 121752
 Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Journal article
  1. Cécile Morlot; Daniel Straume; Katharina Peters; Olav A. Hegnar; Nolwenn Simon; Anne-Marie Villard; Carlos Contreras-Martel; et al. "Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae". Nature Communications (2018): https://doi.org/10.1038/s41467-018-05602-w.
    10.1038/s41467-018-05602-w
  2. Francisco Leisico; Diana V. Vieira; Teresa A. Figueiredo; Micael Silva; Eurico J. Cabrita; Rita G. Sobral; Ana Madalena Ludovice; et al. "First insights of peptidoglycan amidation in Gram-positive bacteria - the high-resolution crystal structure of Staphylococcus aureus glutamine amidotransferase GatD". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-22986-3.
    10.1038/s41598-018-22986-3
  3. Trouve J; Mohamed A; Leisico F; Contreras-Martel C; Liu B; Mas C; Rudner DZ; Rodrigues CDA; Morlot C. "Structural characterization of the sporulation protein GerM from Bacillus subtilis.". Journal of structural biology (2018): http://europepmc.org/abstract/med/30266596.
    10.1016/j.jsb.2018.09.010
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/03/20 Structural and functional studies on Staphylococcus aureus MurT-GatD heterodimer 3rd Annual Users Meeting of iNEXT
iNEXT: Infrastructure for NMR, EM and X-rays for Translational Research (Grenoble, France)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018 - 2018 UCIBIO Annual Meeting (2018 - 2018) (2018 - 2018)
Meeting (Member of the Organising Committee)
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal