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Identification

Personal identification

Full name
Patrícia Filipa Homem de Campos Tavares de Brito

Author identifiers

Ciência ID
5E18-4CEC-E693
ORCID iD
0000-0002-2457-7520
Google Scholar ID
https://scholar.google.com/citations?user=WlmG2MYAAAAJ&hl=pt-PT&authuser=1
Scopus Author Id
57216175171

Addresses

  • UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa. Campus de, Caparica, 2829-516 C, Caparica, Almada, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Evolutionary Biology
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
Education
Degree Classification
2006/02/01
Concluded
 Biology (Doctor of Philosophy)
Major in Ecology, Evolution and Behavior
City University of New York, United States
Affiliation

Science

Category
Host institution 		Employer
2019 - Current Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2013 - Current Invited Assistant Professor (University Teacher) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Outputs

Publications

Journal article
  1. Silva, M; Pontes, A; Franco-Duarte, R; Soares, P; Sampaio, JP; Sousa, MJ; Brito, PH. "A glimpse at an early stage of microbe domestication revealed in the variable genome of Torulaspora delbrueckii an emergent industrial yeast". Molecular Ecology 32 10 (2023): 2396-2412. http://dx.doi.org/10.1111/mec.16428.
    Published • 10.1111/mec.16428
  2. Marques GS; Teles-Reis J; Konstantinides N; Brito, PH; Homem CCF. Corresponding author: Homem CCF. "Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila". Plos Biology 21 5 (2023): e3002115. https://pubmed.ncbi.nlm.nih.gov/37205703/.
    Published
  3. Brandão, AS; Borbinha, J; Pereira, T; Brito, PH; Lourenço, R; Bensimon-Brito, A; Jacinto, A. "A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration". eLife 11 (2022): http://dx.doi.org/10.7554/elife.76987.
    Published • 10.7554/elife.76987
  4. Alves-Barroco, C; Brito, PH; Santos-Sanches, I; Fernandes, AR. "Phylogenetic analysis and accessory genome diversity reveal insight into the evolutionary history of Streptococcus dysgalactiae". Frontiers in Microbiology 13 (2022): 952110. http://dx.doi.org/10.3389/fmicb.2022.952110.
    Published • 10.3389/fmicb.2022.952110
  5. Santos, ARO; Aires, A; Pontes, A; Silva, M; Brito, PH; Groenewald, M; Melo, CGS; et al. "Phaffia brasiliana sp. nov., a yeast species isolated from soil in a Cerrado Atlantic Rain Forest ecotone site in Brazil". International Journal of Systematic and Evolutionary Microbiology 71 11 (2021): http://dx.doi.org/10.1099/ijsem.0.005080.
    Published • 10.1099/ijsem.0.005080
  6. Cabrita, A; David-Palma, M; Brito, PH; Heitman, J; Coelho, MA; Gonçalves, P. "Multiple Pathways to Homothallism in Closely Related Yeast Lineages in the Basidiomycota". mBio 12 1 (2021): e03130-20. http://dx.doi.org/10.1128/mbio.03130-20.
    Published • 10.1128/mbio.03130-20
  7. David-Palma, M; Libkind, D; Brito, PH; Silva, MR; Bellora, N; Coelho, MA; Heitman, J; Gonçalves, P; Sampaio, JP. "The Untapped Australasian Diversity of Astaxanthin-Producing Yeasts with Biotechnological Potential Phaffia australis sp. nov. and Phaffia tasmanica sp. nov.". Microorganisms 8 11 (2020): 1651. https://www.mdpi.com/2076-2607/8/11/1651.
    Published • 10.3390/microorganisms8111651
  8. Pontes, A; Hutzler, M; Brito, PH; Sampaio, JP. "Revisiting the Taxonomic Synonyms and Populations of Saccharomyces cerevisiae Phylogeny, Phenotypes, Ecology and Domestication". Microorganisms 8 6 (2020): 903. http://dx.doi.org/10.3390/microorganisms8060903.
    Published • 10.3390/microorganisms8060903
  9. Gonçalves, P; Gonçalves, C; Brito, PH; Sampaio, JP. "The Wickerhamiella/Starmerella clade - a treasure trove for the study of the evolution of yeast metabolism". Yeast 37 4 (2020): 313-320. http://dx.doi.org/10.1002/yea.3463.
    Published • 10.1002/yea.3463
  10. Torcato, IM; Kasal, MR; Brito, PH; Miller, ST.; Xavier, KB.. "Identification of novel autoinducer-2 receptors in Clostridia reveals plasticity in the binding site of the LsrB receptor family". Journal of Biological Chemistry 294 12 (2019): 4450-4463. http://dx.doi.org/10.1074/jbc.ra118.006938.
    Published • 10.1074/jbc.ra118.006938
  11. Brito, PH; Chevreux, B; Serra, CR; Schyns, G; Henriques, AO; Pereira-Leal, JB. "Genetic competence drives genome diversity in Bacillus subtilis". Genome Biology and Evolution 10 1 (2017): 108-124. http://dx.doi.org/10.1093/gbe/evx270.
    Published • 10.1093/gbe/evx270
  12. Gjini, E; Brito, PH. "Integrating antimicrobial therapy with host immunity to fight drug-resistant infections: classical vs. adaptive treatment". PLOS Computational Biology 12 4 (2016): e1004857. http://dx.doi.org/10.1371/journal.pcbi.1004857.
    Published • 10.1371/journal.pcbi.1004857
  13. Ramos-Silva, P; Brito, PH; Serrano, M; Henriques, AO; Pereira-Leal, JB. "Rethinking the niche of upper-atmosphere Bacteria: draft genome sequences of Bacillus aryabhattai C765 and Bacillus aerophilus C772, isolated from rice fields". Genome Announcements 3 2 (2015): http://dx.doi.org/10.1128/genomea.00094-15.
    Published • 10.1128/genomea.00094-15
  14. Brito, PH; Rocha, EPC; Xavier, KB; Gordo, I. "Natural genome diversity of AI-2 quorum sensing in Escherichia coli: conserved signal production but labile signal reception". Genome Biology and Evolution 5 1 (2012): 16-30. http://dx.doi.org/10.1093/gbe/evs122.
    Published • 10.1093/gbe/evs122
  15. Brito, PH; Guilherme, E; Soares, H; Gordo, I. "Mutation accumulation in Tetrahymena". BMC Evolutionary Biology 10 1 (2010): 354. http://dx.doi.org/10.1186/1471-2148-10-354.
    Published • 10.1186/1471-2148-10-354
  16. Pereira, CS; de Regt, AK; Brito, PH; Miller, ST; Xavier, KB. "Identification of functional LsrB-like autoinducer-2 receptors". Journal of Bacteriology 191 22 (2009): 6975-6987. http://dx.doi.org/10.1128/jb.00976-09.
    Published • 10.1128/jb.00976-09
  17. Brito, PH; Edwards, SV. "Multilocus phylogeography and phylogenetics using sequence-based markers". Genetica 135 3 (2009): 439-455. https://pubmed.ncbi.nlm.nih.gov/18651229/.
    Published • 10.1007/s10709-008-9293-3
  18. Brito, PH. "Contrasting patterns of mitochondrial and microsatellite genetic structure among Western European populations of tawny owls (Strix aluco)". Molecular Ecology 16 16 (2007): 3423-3437. https://pubmed.ncbi.nlm.nih.gov/17688543/.
    Published • 10.1111/j.1365-294X.2007.03401.x
  19. Brito, PH. "The influence of Pleistocene glacial refugia on tawny owl genetic diversity and phylogeography in western Europe". Molecular Ecology 14 10 (2005): 3077-3094. https://pubmed.ncbi.nlm.nih.gov/16101775/.
    Published • 10.1111/j.1365-294X.2005.02663.x
Preprint
  1. Matias, AT; Jacinta-Fernandes, A; Maia, AT; Brag, S; Jacinto, A; Cabral MG; Brito, Patrícia H.. "Differential expression between African-ancestry and White patients diagnosed with Triple-Negative Breast Cancer: EGFR, Myc, Bcl2 and ß-Catenin as ancestry-associated markers". 2022. https://doi.org/10.1101/2020.11.13.381608.
  2. Domingues, N; Calado, RDA; Brito, Patrícia H.; Matthiesen, R; Ramalho, J; Soares, MIL; Pereira, T; et al. "Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages". 2021. https://doi.org/10.1101/2021.01.05.422575.
    https://doi.org/10.1101/2021.01.05.422575
  3. Wilson, A; Pereira, FC; Feliciano, C; Saujet, L; Vultos, T; Couture-Tosi, E; Péchiné, S; et al. "Structure and assembly of a Clostridioides difficile spore polar appendage". 2020. http://dx.doi.org/10.1101/468637.
    10.1101/468637
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021 Evolution of opportunistic pathogenicity in S. cerevisiae. Conference on Yeasts Genetics and Molecular Biology
Vienna, AUSTRIA (virtual meeting) (virtual meeting, Austria)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/08/05 - 2022/08/08 Seventh Annual Meeting of the International Society for Evolution, Medicine, and Public Health (2022/08/05 - 2022/08/08)
Conference (Member of the Scientific Committee)
 NOVA Medical School, UNL & Instituto Gulbenkian de Ciência, Portugal
2014 - 2014 Symposium on Evolution and Cancer (2014 - 2014)
Symposium (President of the Organising Committee)
 Fundação Champalimaud, Portugal

Instituto Gulbenkian de Ciência, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Associação Portuguesa de Biologia Evolutiva (APBE), Portugal

Conference scientific committee

Conference name Conference host
2022/07/05 - 2022/07/07 INTERNATIONAL SOCIETY FOR EVOLUTION, MEDICINE & PUBLIC HEALTH. NOVA Medical School, Instituto Gulbenkian de Ciência

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021 - Current Fundamentals of Computational Biology Master in Computational Biology and Bioinformatics, (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021 - Current Advanced Evolutionary Genomics Master in Computational Biology and Bioinformatics (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013 - Current Evolutionary Medicine Integrated Master in Medicine (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020 - 2021 Genomics in Medical Microbiology Master in Medical Microbiology (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal