Personal identification

Full name

João Gonçalo Leal de Oliveira e Silva Frade

Citation names

• Frade, João Gonçalo

Author identifiers

Ciência ID

5C11-74B9-E2D7

ORCID iD

0000-0001-5037-5335

Email addresses

• joao.goncalo.frade@ulscoimbra.min-saude.pt (Professional)

Knowledge fields

• Medical and Health Sciences - Basic Medicine - Pathology
• Natural sciences - Biological Sciences - Biochemistry

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Spanish; Castilian	Intermediate (B1)	Intermediate (B1)	Beginner (A1)	Intermediate (B1)

	Degree	Classification
2013 Concluded	Mestrado Integrado em Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal "CONSELHO MÉDICO-LEGAL: QUE REALIDADE?" (THESIS/DISSERTATION)	14
2008 Concluded	Bioquímica (Doutoramento) Major in Especialidade: Toxicologia Bioquímica Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Real-time Change of Nitric Oxide in Rat Hippocampal Slices and Astrocytic Glutathione Release Via Glutamate-dependent Pathawys" (THESIS/DISSERTATION)
2001 Concluded	Bioquímica (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "n/a" (THESIS/DISSERTATION)	16

Science

	Category Host institution	Employer
2009/01/01 - 2013/07/31	Postdoc (Research)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2018/08 - 2020/02/29	Invited Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
2016 - 2018	Invited Assistant (Polytechnic Teacher)	Instituto Politécnico de Leiria, Portugal
2015 - 2016	Assistant (Polytechnic Teacher)	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal

Other Careers

	Category Host institution	Employer
2019/08/01 - Current	Assistente (Médica)	Centro Hospitalar e Universitário de Coimbra EPE, Portugal
	Serviço de Patologia Clínica, Centro Hospitalar e Universitário de Coimbra, Portugal
2015/01/01 - 2018/12/31	Interno (Médica)	Centro Hospitalar e Universitário de Coimbra EPE, Portugal
	Serviço de Patologia Clínica, Centro Hospitalar e Universitário de Coimbra, Portugal
2014/01/01 - 2014/12/31	Interno (Médica)	Centro Hospitalar e Universitário de Coimbra EPE, Portugal

Others

	Category Host institution	Employer
2007/01/01 - 2009/01/01	Subcontracted Consultant, in charge of preparation, translation and revision of texts for marketing authorisation, SPC, PIL and labelling of medicinal products	Phagecon, Portugal
2006/01/01 - 2006/07/31	Part-time job at Paediatric Hospital, Coimbra, in charge of the organizing and management of Medical Screening Data	Centro Hospitalar e Universitario de Coimbra EPE Hospital Pediátrico de Coimbra, Portugal

Publications

Book chapter	Frade, João. "Nitric oxide monitoring in hippocampal brain slices using electrochemical methods". 111-125. Academic Press, 2002. https://doi.org/10.1016/S0076-6879(02)59176-X
Journal article	Catarata, Maria Joana; Medeiros, Rui; Oliveira, Maria José; Pêgo, Alice; Frade, João Gonçalo; Martins, Maria Fátima; Robalo Cordeiro, Carlos Robalo; et al. "Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies". Cancers 12 12 (2020): 3834. http://dx.doi.org/10.3390/cancers12123834. Open access • 10.3390/cancers12123834 Fadiga, Lúcia; Saraiva, Joana; Catarino, Diana; Frade, João; Melo, Miguel; Paiva, Isabel. "Adult-onset autoimmune diabetes: comparative analysis of classical and latent presentation". Diabetology & Metabolic Syndrome 12 1 (2020): http://dx.doi.org/10.1186/s13098-020-00616-1. 10.1186/s13098-020-00616-1 Cabral, Luís; Afreixo, Vera; Meireles, Rita; Vaz, Miguel; Frade, João-Gonçalo; Chaves, Catarina; Caetano, Marisa; Almeida, Luís; Paiva, José-Artur. "Evaluation of procalcitonin accuracy for the distinction between gram-negative and gram-positive bacterial sepsis in burn patients". (2019): http://hdl.handle.net/10773/25670. 10.1093/jbcr/iry058 Lages, Adriana De Sousa; Frade, João Gonçalo; Oliveira, Diana; Paiva, Isabel; Oliveira, Patrícia; Rebelo-Marques, Alexandre; Carrilho, Francisco. "Late-Night Salivary Cortisol: Cut-Off Definition and Diagnostic Accuracy for Cushing’s Syndrome in a Portuguese Population". (2019): https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11265. 10.20344/amp.11265 Frade, João. "Stimulation of NMDA and AMPA glutamate receptors elicits distinct concentration dynamics of nitric oxide in rat hippocampal slices". Hippocampus 19 7 (2009): 603-611. http://dx.doi.org/10.1002/hipo.20536. 10.1002/hipo.20536 Frade, João. "Glutamate induces release of glutathione from cultured rat astrocytes – a possible neuroprotective mechanism?". Journal of Neurochemistry 105 4 (2008): 1144-1152. http://dx.doi.org/10.1111/j.1471-4159.2008.05216.x. 10.1111/j.1471-4159.2008.05216.x Frade, João. "Electrochemical measurement of endogenously produced nitric oxide in brain slices using Nafion/o-phenylenediamine modified carbon fiber microelectrodes". Analytica Chimica Acta 535 1 (2005): 1-7. http://www.sciencedirect.com/science/article/pii/S0003267004016526. https://doi.org/10.1016/j.aca.2004.12.017 Frade, João. "Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions". Molecular Aspects of Medicine 25 1 (2004): 75-89. http://www.sciencedirect.com/science/article/pii/S0098299704000111. https://doi.org/10.1016/j.mam.2004.02.010
Thesis / Dissertation	Frade, João Gonçalo Leal de Oliveira e Silva. "Conselho médico-legal : que realidade?". Master, 2013. http://hdl.handle.net/10316/84295. Frade, João Gonçalo Leal de Oliveira e Silva. "Real-time change of nitric oxide in rat hippocampal slices and astrocytic glutathione release via glutamate-dependent pathways". PhD, 2008. http://hdl.handle.net/10316/7449.