I am an assistant professor at FCT (Universidade Nova) and a group leader at the same institution, where I supervise a team
composed of two junior students, one researcher with a master’s degree, and one post-doc. Over the course of my career, I
have independently secured eight external competitive grants and fellowships for my team, totaling approximately €1.2 million.
I have authored 44 publications, including 30 international papers, with 27 peer-reviewed articles in top journals such as
Nature Communications, Molecular Cell, and The Journal of Experimental Medicine. My work has achieved an average impact factor
of 10.1 per paper, an average of 77 citations per paper, and a total of at least 2,082 citations (according to Google Scholar).
Sixteen of these publications were as first or corresponding author, and my research has been highlighted in Nature Immunology,
Faculty of 1000, and JEM. ~
I graduated in Biology from the University of Lisbon (1994) and pursued my doctoral studies at the Institut Pasteur in Paris,
earning a Ph.D. in Immunology from UPMC (2001). Afterward, I moved to The Rockefeller University in New York, where I worked
first as a postdoctoral fellow and later as a research associate, focusing on the molecular mechanisms of antibody formation.
In 2008, I returned to Portugal to establish my research group at the IGC, addressing two fundamental aspects of B cells:
1) The interplay between mechanisms that promote genetic diversity in somatic cells and DNA repair; 2) The epigenetics of
mono-allelic expression. I was awarded a Ciência 2008 contract to launch my independent research career at the IGC, later
earning an Associate Researcher position (IF 2015). I subsequently moved to CEDOC (FCM, Universidade Nova), where I conducted
research from 2016 to 2022 supported by three FCT grants. This work enabled me to make key contributions to understanding
the regulation of Activation-Induced Deaminase (AID)—the editor of immunoglobulin genes—and the process of V(D)J recombination.
In 2022, I was hired as an Assistant Professor by FCT (Nova) and as the director of Genetagus, the first Portuguese gene editing
company, with a team I trained at NMS as part of a service I started in 2019. The service and then the company delivered genetically
edited cells to top research institutions in Europe and the United States until April 2024.
Throughout my career, I have supervised six postdoctoral researchers, four Ph.D. students (all graduated), and six master’s
students (all graduated). I have also filed a provisional patent and reviewed manuscripts for major journals, including Cell,
JEM, Nature Methods, Nucleic Acids Research, and Infection, and Genetics and Evolution. Additionally, I have served as a reviewer
for the FCT and as the main opponent in five national and one international Ph.D. thesis defenses. I have delivered invited
talks at national institutions and international venues in Spain, Sweden, and Israel. Moreover, I co-organized modules for
four international Ph.D. programs and contributed to organizing two national and one international scientific meeting. My
collaborative work includes projects with world-renowned experts such as A. Gimelbrant (Harvard Medical School, USA) and A.
Ramiro (CNIC, Spain). I have served on the Selection Committee of the International Plants for Life Ph.D. Program (2016) and
the editorial boards of SpringerPlus (2015), Developmental Epigenetics (2022), and Microbes & Immunity (2023). In 2023, I
co-founded Almanaque, an online magazine of ideas. I have been at the forefront of introducing modern genetics techniques
in Portugal, including transgenic mice models and CRISPR/Cas editing of cell lines. Currently, I am working on a commissioned
book on Genetics.