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Fernanda Murtinheira is PhD student at the NOVA University of Lisbon, Instituto de Tecnologia Química e Biológica, where she attends the PhD Program in Molecular Biosciences. Born in 1979, graduated in Professores do 2º ciclo do Ensino Básico, variante de Matemática/ Ciências da Natureza at the Instituto Politécnico de Viseu, Escola Superior de Educação de Viseu (2001). Completed the Master in Biomedical Sciences in 2016 by Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon. She is (co)-author of 7 papers published in international peer-reviewed journals and 1 book section. She has received 1 award and/or honor. Her research works have also been presented in 1 oral presentation and 9 poster communications in different national and international meetings.
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Identification

Personal identification

Full name
Fernanda Ivanira Henriques Murtinheira Ferreira

Citation names

  • Murtinheira, Fernanda

Author identifiers

Ciência ID
5A1D-B52E-AF88
ORCID iD
0000-0002-5096-5631

Email addresses

  • fiferreira@fc.ul.pt (Professional)

Telephones

Telephone
  • 21750000 Ext.: 28175 (Professional)

Addresses

  • Cell Structure and Dynamics Lboratory, Dep. of Chemistry and Biochemistry (DQB), Faculty of Sciences, University of Lisbon, Edifício C8, Campo Grande, 1749-016 , Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Intermediate (B1) Advanced (C1) Intermediate (B1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Beginner (A1) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2016/04/01
Concluded
 Mestrado em Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"Estudo da resistência de Plasmodium falciparum à artemisinina e derivados: desenvolvimento e implementação de testes in vitro para avaliação da viabilidade" (THESIS/DISSERTATION)
 17
2001/06/05
Concluded
 Professores do 2º ciclo do Ensino Básico, variante de Matemática/ Ciências da Natureza (Licenciatura)
Instituto Politécnico de Viseu Escola Superior de Educação de Viseu, Portugal
"n/a" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2017/04/01 - 2017/12/31 Research Trainee (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/04/01 - 2016/08/01 Research Trainee (Research) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Others

Category
Host institution 		Employer
2018/01/01 - Current PhD student - PhD Program in Molecular Biosciences Fundação para a Ciência e a Tecnologia, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2013/10/01 - 2016/04/01 Master student - Biomedical Sciences Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projects

Grant

Designation Funders
2018/01/01 - Current Towards a smaller but functional sacsin protein for ARSACS gene therapy
SFRH/BD/133220/2017
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2022/01/01 - 2024/12/31 Células viscoelásticas - novas metodologias experimentais com base em microscopia de força atómica
PTDC/FIS-MAC/2741/2021
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Fernanda Murtinheira. "Parque Florestal de Monsanto". In Um bosque perto de si – Conhecer ecossistemas florestais, 102-102. Lisboa, Portugal: Ciência Viva – Agência Nacional para a Cultura Científica e Tecnológica, 2012.
    Published
Conference poster
  1. Murtinheira, Fernanda. "Ataxia-related protein sacsin regulates the intermediate filament network in glial cells". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  2. Murtinheira, Fernanda. "Deletion of the ataxia-related chaperone sacsin disrupts the intermediate filaments network in glial cells". Paper presented in Ciências Research Day, Faculty of Sciences of the University of Lisbon, 2021.
  3. Murtinheira, Fernanda. "Ataxia related protein sacsin knockout disrupts the intermediate filaments network in glial cells". Paper presented in IDPSeminars. Magnus Kjaergaard (Aarhus University) and Alex Holehouse (Washington University School of Medicine), 2021.
  4. Murtinheira, Fernanda. "Ataxia related protein sacsin knockout disrupts the intermediate filaments network in glial cells". Paper presented in XXI SPB National Congress of Biochemistry, 2021.
  5. Murtinheira, Fernanda. "Towards a smaller but functional sacsin protein for ARSACS gene therapy". Paper presented in 10th ITQB NOVA PhD Students' Meeting, 2020.
  6. Murtinheira, Fernanda. "Ataxia related protein sacsin knockout disrupts the intermediate filaments network in glial cells". Paper presented in BioISI Research Day, 2020.
  7. Murtinheira, Fernanda. "Towards a smaller but functional sacsin protein for ARSACS gene therapy". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, 2019.
  8. Murtinheira, Fernanda. "Dinuclear Zinc complexes as specific inhibitors of STAT3 phosphorylation at Tyrosine 705". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, 2019.
  9. Murtinheira, Fernanda. "Towards a smaller but functional sacsin protein for ARSACS gene therapy". Paper presented in IV Symposium of Portuguese Glial Network., 2019.
Journal article
  1. Murtinheira, Fernanda; Migueis, Mafalda; Letra-Vilela, Ricardo; Diallo, Mickael; Quezada, Andrea; Valente, Cláudia A.; Oliva, Abel; et al. "Sacsin Deletion Induces Aggregation of Glial Intermediate Filaments". Cells 11 2 (2022): 299. http://dx.doi.org/10.3390/cells11020299.
    Open access • 10.3390/cells11020299
  2. Letra-Vilela, Ricardo; Quiteres, Ricardo; Murtinheira, Fernanda; Crevenna, Alvaro; Hensel, Zach; Herrera, Federico. "New tools for the visualization of glial fibrillary acidic protein in living cells". Experimental Results 1 (2020): http://dx.doi.org/10.1017/exp.2020.1.
    10.1017/exp.2020.1
  3. Letra-Vilela, Ricardo; Cardoso, Beatriz; Silva-Almeida, Catarina; Maia Rocha, Ana; Murtinheira, Fernanda; Branco-Santos, Joana; Rodriguez, Carmen; et al. "Can asymmetric post-translational modifications regulate the behavior of STAT3 homodimers?". FASEB BioAdvances 2 2 (2020): 116-125. http://dx.doi.org/10.1096/fba.2019-00049.
    10.1096/fba.2019-00049
  4. Horta, Pedro; Henriques, Marta S. C.; Brás, Elisa M.; Murtinheira, Fernanda; Nogueira, Fátima; O’Neill, Paul M.; Paixão, José A.; Fausto, Rui; Cristiano, Maria L. S.. "On the ordeal of quinolone preparation via cyclisation of aryl-enamines; synthesis and structure of ethyl 6-methyl-7-iodo-4-(3-iodo-4-methylphenoxy)-quinoline-3-carboxylate". Pure and Applied Chemistry 89 6 (2017): 765-780. http://dx.doi.org/10.1515/pac-2016-1119.
    Published • 10.1515/pac-2016-1119
  5. Ferraz, R.; Noronha, J.; Murtinheira, F.; Nogueira, F.; Machado, M.; Prudêncio, M.; Parapini, S.; et al. "Primaquine-based ionic liquids as a novel class of antimalarial hits". RSC Advances 6 61 (2016): 56134-56138. http://www.scopus.com/inward/record.url?eid=2-s2.0-84975078549&partnerID=MN8TOARS.
    10.1039/c6ra10759a
  6. Machado, M; Murtinheira, F; Lobo, E; Nogueira, Fátima; Instituto de Higiene e Medicina Tropical (IHMT); Vector borne diseases and pathogens (VBD); Global Health and Tropical Medicine (GHTM). "Whole-cell SYBR Green I assay for antimalarial activity assessment". (2016): https://www.jscimedcentral.com/MedicalMicrobiology/medicalmicrobiology-2-1010.pdf.
  7. Faísca Phillips, A.M.; Nogueira, F.; Murtinheira, F.; Barros, M.T.. "Synthesis and antimalarial evaluation of prodrugs of novel fosmidomycin analogues". Bioorganic and Medicinal Chemistry Letters 25 10 (2015): 2112-2116. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937763937&partnerID=MN8TOARS.
    10.1016/j.bmcl.2015.03.077
Thesis / Dissertation
  1. MURTINHEIRA, Fernanda Ivanira Henriques. "Estudo da resistência de Plasmodium falciparum à artemisinina e derivados: desenvolvimento e implementação de testes in vitro para avaliação da viabilidade". Master, 2016. http://hdl.handle.net/10362/19141.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021 Sacsin deletion promotes intermediate filaments aggregation in glial cells: potential implications for ARSACS. V Symposium of the Portuguese Glial Network
(Évora, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021 - 2021 Festival Internacional de Ciência (FICA )- Speed Dating
Festival
2021 - 2021 Ciências Research Day
2020 - 2020 Centro de Testes de Ciências Ulisboa, Volunteer
Other

Mentoring / Tutoring

Topic Student name
2021 - Current Patricia Nascimento
2020 - Current Luís Santos
2020/09 - 2022/03 Daniela Alves
2020/09 - 2022/03 Mafalda Migueis
2020/09 - 2021/12 Pedro Peralta
2021/07 - 2021/07/31 Catarina Sofia Tracanas
2021/07 - 2021/07 Inês Sofia Augusto
2021/06 - 2021/07 Rafaela Marimon
2019/10 - 2021/07 Beatriz Teixeira
2018/09 - 2019/12 Ricardo Marques
2018/09 - 2019/12 Ana Catarina Narciso
2018/09 - 2019/12 Ricardo Quiteres
Distinctions

Award

2011 1st place in the category 2nd cycle in the academic year 2010/2011, in the Project Um bosque perto de si
Ciência Viva, Portugal