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Patrícia Frederico Susano is a Ph.D. student in Pharmaceutical Sciences at the Faculty of Pharmacy, University of Coimbra. This PhD thesis project aims to study the anti-inflammatory and protective capacity of components from two brown seaweeds, namely Carpomitra costata and Sargassum muticum, and a red seaweed Sphaerococcus coronopifolius, on in vitro and ex vivo skin models of psoriasis, specifically to evaluate the ability of those seaweed-derived components to inhibit the activation of MAPKs and NF-kB pro-inflammatory signalling pathways, as well as to modulate the expression of cytokines and chemokines involved in the pathophysiology of psoriasis. She has a MSc in Biotechnology of Marine Resources (2021) and a BSc in Marine Biology and Biotechnology (2017) by School of Tourism and Maritime Technology (ESTM) - Polytechnic of Leiria. Her research work in the field of Marine Biotechnology is focused on the search of marine compounds isolated from marine organisms, namely seaweeds, with therapeutic interest for dermatological and pharmacology purposes (e.g., anti-inflammatory, anti-psoriasis, antioxidant, photoprotective and antimicrobial activity). Her MSc thesis focused on the study of the biological potential of the brown seaweed, C. costata for dermatological applications, evaluating the antioxidant, anti-enzymatic, and antimicrobial activities. Furthermore, she evaluated the photoprotective and anti-inflammatory activity of the C. costata fractions on in vitro cellular models, using fibroblasts and macrophages cells, respectively. At the same time, she also evaluated the dermatological potential of two more brown seaweeds, namely S. muticum and Saccorhiza polyschides. In 2020, she integrated the Covid19 Diagnostic Center at the MARE-IPLeiria, as researcher volunteer, and integrated the project DisCovEr+ granted to CoviD19 Diagnostic Center. She participated in 8 projects on competitive national and international calls and has 12 full papers in scientific journals with peer review (3 as author and 9 as co-author); with Q1 score and 1 book chapter. She also participated in 10 communications in international conferences, including poster and oral communications. She is a certified diver and has completed a Graduate Program in Scientific Diving, performing the following SSI specialty programs: Deep Diving, Enriched Air Nitrox Level 2 (40%), Navigation, Night Diving and Limited Visibility, React Right, Stress & Rescue, and Science of Diving.
Identification

Personal identification

Full name
Patrícia Frederico Susano
Date of birth
1994/07/23
Gender
Female

Citation names

  • Susano, Patrícia

Author identifiers

Ciência ID
581E-146A-9945
ORCID iD
0000-0003-1426-2071

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1) Upper intermediate (B2)
Education
Degree Classification
2023/01/01 - 2027
Ongoing
PhD Programme in Pharmaceutical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024/03/06 - 2024/06/12
Concluded
Curso Básico de Chinês (Outros)
Instituto Politécnico de Leiria, Portugal
2023/07/10 - 2023/07/17
Concluded
Advanced Course Regulatory Affairs and Patents (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Farmácia, Portugal
14/20
2023/03/06 - 2023/03/09
Concluded
Advanced Course Pharmacological trends in drug discovery and development (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Farmácia, Portugal
18/20
2023/02/13 - 2023/02/24
Concluded
Advanced Course Principles and Practices in Drug Development (Curso de doutoramento (conclusão de unidades curriculares))
Center for Neuroscience and Cell Biology , Portugal
18/20
2023/02/06 - 2023/02/10
Concluded
Advanced Course Pharmacogenomics (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Medicina, Portugal
18/20
2021/07 - 2022/06/29
Concluded
Postgraduate Programme in Scientific Diving (Pós-Graduação)
Instituto Politécnico de Leiria, Portugal
19/20
2021/08/01 - 2022/02/11
Concluded
Advanced Research Course in Marine Science and Technology (Outros)
School of Tourism and Maritime Technology - Polytechnnic of Leiria, Portugal
2018 - 2021
Concluded
Marine Resources Biotecnology (Mestrado)
Instituto Politécnico de Leiria, Portugal
"Potencial Dermocosmético da macroalga Carpomitra costata" (THESIS/DISSERTATION)
18/20
2017/10/09 - 2017/10/13
Concluded
Curso de Identificação de Peixes dos Ecossistemas Fluviais de Portugal (Outros)
Museu Nacional de História Natural e Ciência, Portugal
2013 - 2017
Concluded
Marine Biology and Biotechnology (Licenciatura)
Instituto Politécnico de Leiria, Portugal
"Monitorização da biomassa e modelos de crescimento - Academia Aquatropolis" (THESIS/DISSERTATION)
14/20
Affiliation

Science

Category
Host institution
Employer
2021/07/01 - Current Researcher (Research) Instituto Politécnico de Leiria, Portugal
2020/10 - 2021/06/30 Researcher (Research) Covid-19 Diagnostic Centre - Polytechnic of Leiria, Portugal, Portugal
2020/07/27 - 2020/10/27 Researcher (Research) Instituto Politécnico de Leiria, Portugal
2020/09 - 2020/10 Researcher (Research) Researcher Volunteer - COVID 19 Diagnostic Center - Polytechnic Institute of Leiria, Portugal

Others

Category
Host institution
Employer
2024/02/01 - Current Collaborating member Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2023/01/01 - Current Collaborating member MARE - Centro de Ciências do Mar e do Ambiente, Portugal
2023/01/01 - Current PhD student on Pharmaceutical Sciences Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2021/03/18 MsC student on Marine Resources Biotechnology Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2019 - 2021 Master's degree in Biotechnology of Marine Resources Instituto Politécnico de Leiria, Portugal
Projects

Grant

Designation Funders
2023/01/01 - Current Anti-inflammatory effects of seaweed-derived components in skin cellular models of psoriasis
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2021/11/01 - Current NEURONS - Natural products as key drivers in the development of nEUropROtective therapeutic ageNtS
FCT/DRI/PNAAE 2021.09608.CBM
Researcher
MARE - Polytechnic of Leiria, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/07/01 - 2022/06/30 Discover+ - Development and optimization of Covid19 diagnosis as an emergency response to the pandemic
02/SAICT/2020
Researcher
European Regional Development Fund
Concluded
2019/07 - 2022/06/30 CROSS-ATLANTIC – CReating Opportunities from Seaweed Sulfated polysaccharides for Application in Therapeutics
PTDC/BIA-OUT/29250/2017
Other
Instituto Politécnico de Leiria, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/07 - 2021/03 POINT4PAC - Precision oncology and innovative therapies and technologies
SAICTPAC/0019/2015 - LISBOA-01-0145-FEDER-016405
Other
Instituto Politécnico de Leiria, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/07/27 - 2020/10/27 Summer School "Exploration and Valorization of Marine Resources"
-
Researcher
Instituto Politécnico de Leiria, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/07 - 2019/11/30 Red2Discovery - The Red macro-algae Sphaerococcus coronopifolius and Asparagopsis armata as targets for marine drug Discovery
PTDC/MAR-BIO/6149/2014
Other
Instituto Politécnico de Leiria, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2024/01 - Current BEAP-MAR
EAPA_0032/2022
Researcher
European Union
Ongoing
Outputs

Publications

Book chapter
  1. Silva, Joana; Martins, A.; Susano, Patrícia; Alves, Celso. "Materials with Marine Origins for Cancer Therapy". In Handbook of the Extracellular Matrix, 1-23. Springer International Publishing, 2024.
    Published • 10.1007/978-3-030-92090-6_58-1
Conference poster
  1. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Pinteus, Susete; Cruz, Maria Teresa; Gabig-Ciminska, Magdalena; Pedrosa, Rui. "Cytotoxic and anti-inflammatory effects of seaweed-derived compounds in human keratinocytes (HaCaT cells)". Paper presented in International Symposium on Marine Natural Products and European Conference on Marine Natural Products, 2023.
  2. Luz, Inês; Sánchez-Álvarez, Candela; Silva, Joana; Susano, Patrícia; Alves, Celso; Martins, Alice; Pinteus, Susete; Pedrosa, Rui. "Dermatological potential of the brown seaweed Bifurcaria bifurcata collected off the Portuguese coastline". Paper presented in Trends in Natural Products Research: A PSE Young Scientist' Meeting, 2022.
  3. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Goettert, Márcia; Pedrosa, Rui. "Exploring the brown seaweed Sargassum muticum and Saccorhiza polyschides for dermatological applications". Paper presented in European Conference of Marine Natural Products, 2021.
  4. Silva, Joana; Morais, Fernando; Alves, Celso; Susano, Patrícia; Martins, Alice; Pinteus, Susete; Pedrosa, Rui. "Neuroprotective and anti-inflammatory activities of sulfated polysaccharides from seaweeds collected off Peniche coast (Portugal)". Paper presented in European Conference of Marine Natural Products, 2021.
  5. Faísca, Francisco; Silva, Dário; Grilo, Inês R.; Correia, Vanessa; Alves, Celso; Silva, Joana; Susano, Patrícia; et al. Corresponding author: Branco, Luis. "TACKLING INFECTIOUS DISEASES USING PHARMACEUTICAL IONIC LIQUIDS". Paper presented in 7th Portuguese Young Chemists Meeting, 2021.
Journal article
  1. Perlikowska, Renata; Silva, Joana; Alves, Celso; Susano, Patrícia; Zaklos-Szyda, Malgorzata; Skibska, Agnieszka; Adamska-Bartlomiejczyk, Anna; et al. "Neuroprotective and Anti-inflammatory Effects of Rubiscolin-6 Analogs with Proline Surrogates in Position 2". Neurochemical Research (2023): http://dx.doi.org/10.1007/s11064-023-04070-z.
    Published • 10.1007/s11064-023-04070-z
  2. Patrícia Frederico Susano; Joana Silva; Celso Alves; Alice Martins; Susete Pinteus; Helena Gaspar; Márcia Inês Goettert; Rui Pedrosa. "Saccorhiza polyschides—A Source of Natural Active Ingredients for Greener Skincare Formulations". Molecules (2022): https://www.mdpi.com/1420-3049/27/19/6496.
    10.3390/molecules27196496
  3. Renata Perlikowska; Joana Silva; Celso Alves; Patrícia Frederico Susano; Rui Pedrosa. "The Therapeutic Potential of Naturally Occurring Peptides in Counteracting SH-SY5Y Cells Injury". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/19/11778.
    10.3390/ijms231911778
  4. Silva, Joana; Alves, Celso; Susano, Patricia; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Alfonso, Amparo; Pedrosa, Rui. "Exploring marine resources against neurological disorders– the neuroprotective and anti-inflammatory potential of the brown seaweed Bifurcaria bifurcata". Journal of Applied Phycology (2022): http://dx.doi.org/10.1007/s10811-022-02794-z.
    10.1007/s10811-022-02794-z
  5. Pinteus, Susete; Susano, Patrícia; Alves, Celso; Silva, Joana; Martins, Alice; Pedrosa, Rui. "Seaweed’s Role in Energetic Transition—From Environmental Pollution Challenges to Enhanced Electrochemical Devices". Biology 11 3 (2022): 458. http://dx.doi.org/10.3390/biology11030458.
    10.3390/biology11030458
  6. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Goettert, Márcia Ines; Pedrosa, Rui. "Mitigating the negative impacts of marine invasive species – Sargassum muticum - a key seaweed for skincare products development". Algal Research 62 (2022): 102634. http://dx.doi.org/10.1016/j.algal.2022.102634.
    10.1016/j.algal.2022.102634
  7. Pinteus, S; Susano, Patrícia; Alves, Celso; Silva, Joana; Martins, Alice; Pedrosa, Rui. "Seaweed role in Energetic Transition - From environmental pollution challenges to enhanced electrochemical devices". Biology (2022):
    Accepted
  8. Alves, Joana; Gaspar, Helena; Silva, Joana; Alves, Celso; Martins, Alice; Teodoro, Fernando; Susano, Patrícia; Pinteus, Susete; Pedrosa, Rui. "Unravelling the Anti-Inflammatory and Antioxidant Potential of the Marine Sponge Cliona celata from the Portuguese Coastline". Marine Drugs 19 11 (2021): 632. http://dx.doi.org/10.3390/md19110632.
    10.3390/md19110632
  9. Silva, Joana; Alves, Celso; Pinteus, Susete; Susano, Patrícia; Simões, Marco; Guedes, Miguel; Martins, Alice; et al. "Disclosing the potential of eleganolone for Parkinson’s disease therapeutics: Neuroprotective and anti-inflammatory activities". Pharmacological Research 168 (2021): 105589. http://dx.doi.org/10.1016/j.phrs.2021.105589.
    10.1016/j.phrs.2021.105589
  10. Calado, Maria da Luz; Silva, Joana; Alves, Celso; Susano, Patrícia; Santos, Débora; Alves, Joana; Martins, Alice; et al. "Marine endophytic fungi associated with Halopteris scoparia (Linnaeus) Sauvageau as producers of bioactive secondary metabolites with potential dermocosmetic application". PLOS ONE 16 5 (2021): e0250954. http://dx.doi.org/10.1371/journal.pone.0250954.
    10.1371/journal.pone.0250954
  11. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Gaspar, Helena; Pinteus, Susete; Mouga, Teresa; et al. "Unravelling the Dermatological Potential of the Brown Seaweed Carpomitra costata". Marine Drugs (2021):
    10.3390/md19030135
  12. Silva, Joana; Alves, Celso; Martins, Alice; Susano, Patrícia; Simões, Marco; Guedes, Miguel; Rehfeldt, Stephanie; et al. "Loliolide, a New Therapeutic Option for Neurological Diseases? In Vitro Neuroprotective and Anti-Inflammatory Activities of a Monoterpenoid Lactone Isolated from Codium tomentosum". International Journal of Molecular Sciences (2021):
    10.3390/ijms22041888
Thesis / Dissertation
  1. Susano, Patrícia. "Potencial dermocosmético da macroalga Carpomitra costata". Master, Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, 2021.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09/07 Taking full potential of Saccorhiza polyschides: greener skincare products and production of biochars International Symposium on Marine Natural Products and European Conference on Marine Natural Products
(Granada, Spain)
2023/09/03 Peptides - promising therapeutic candidates for neuroprotection 26th Polish Peptide Symposium
(Poland)
2023/07/03 Anti-inflammatory effects of seaweed-derived components in skin cellular models of psoriasis Journal Club
2023/03/15 Dermatological potential of the Brown Seaweed Carpomitra costata Class of the Marine Biotechnology curricular unit of the degree in Biotechnology
Escola Superior de Turismo e Tecnologia do Mar, Politécnico de Leiria (Peniche, Portugal)
2022/05/25 Exploring the antifouling potential of the red seaweed Plocamium Cartilagineum Trends in Natural Products Research: A PSE Young Scientist¿ Meeting
(Kolymbari, Greece)
2022/05/24 Sulfated polysaccharides isolated from seaweeds collected off Portugal and Brazil coastlines: effects against microorganisms related to skin disorders Trends in Natural Products Research: A PSE Young Scientist’ Meeting
(Kolymbari, Greece)
2021/08 Dermatological potential of sulfated polysaccharides isolated from seaweeds collected in Portugal and Brazil coastlines European Conference of Marine Natural Products
2020 Biotecnologia Azul – Um mar de soluções para problemas reais específicos da sociedade e da economia. XV Dia de Biologia Marinha e Biotecnologia
ESTM-Politécnico de Leiria, Peniche, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023 - Current Pharma Day - Encontro Anual de Estudantes de Doutoramento em Ciências Farmacêuticas (2023/11/24 - 2023/11/24)
Conference (Member of the Organising Committee)
2023/11/17 - 2023/11/19 Ocean Hackathon 8 (2023/11/17 - 2023/11/19)
2023/09/25 - 2023/09/27 World Seafood Congress 2023 in association with 13th International Conference on Mulluscan Shellfish Safety (2023/09/25 - 2023/09/27)
Congress (Other)
MARE - Centro de Ciências do Mar e do Ambiente, Portugal

Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/04/23 - 2024/04/23 Research Teacher in the Erasmus+ Group Mobility Project from Carl-Fuhlrott-Gymnasium, Wuppertal, Germany
Other
2024/04/18 - 2024/04/19 Organization of the workshop entitled "Macroalgas como fonte de compostos bioativos com aplicação terapêutica e biotecnológica" Ocean Open Day 2024
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2024/03/01 - 2024/03/01 Workshop - Mendeley Reference Manager: gestor de referências bibliográficas
Workshop
Universidade de Coimbra Biblioteca das Ciências da Saúde, Portugal
2023/09/30 - 2023/09/30 Picnic com Saúde
Other
Picnic com Saúde
Faculdade de Farmácia, Universidade de Coimbra, Portugal
2023/09/29 - 2023/09/29 Volunteer at the European Researchers Night
Other
European Researchers Night
2023/09/03 - 2023/09/08 Participation in International Symposium on Marine Natural Products (MaNaPro) and European Conference on Marine Natural Products (ECMNP), Granada, Spain
Conference
2023/07/03 - 2023/07/07 Support for the participant during the Summer Internship under the Ciência Viva no Laboratório programme - "From the Sea to the Laboratory: bioactive potential of marine natural products". 27th edition - Ciência Viva no Laboratório
2023/05/04 - 2023/05/04 Open Day Industry
Other
Open Day Industry
Politécnico de Leiria, Portugal
2022/05/23 - 2022/05/26 Participation on Trends in Natural Products Research: A PSE Young Scientist’ Meeting, Kolymbari, Greece
Conference
2022/05/16 - 2022/05/18 Participation on Ciência 2022 - Encontro com a Ciência e Tecnologia em Portugal
Other
2021/08/30 - 2021/09/01 Participation on conference - XI European Conference on Marine Natural Products, Galway, Ireland
Conference
XI European Conference on Marine Natural Products, Galway, Ireland
2020/10/12 - 2020/11/02 Workshop - Comunicar Ciência Clara
Workshop
Comunicar Ciência Clara
Instituto Politécnico de Leiria MARE, Portugal
2020/07/27 - 2020/10/27 Summer School "Exploration and Valorization of Marine Resources"
Instituto Politécnico de Leiria, Portugal
2020/02/10 - 2020/02/11 Conducting a workshop in collaboration with the organization of "Ocean Open Day - developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme "Seaweeds and therapeutics and biotechnology applications"
Workshop
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2018/11/07 - 2018/11/07 Produção de Gracilaria gracillis em laboratório
Workshop
Workshop Cultivo de macroalgas - Produção de Gracilaria gracillis em laboratório
Instituto Politécnico de Leiria MARE, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2023 - Current Algal Research (2211-9264) Elsevier
2023 - Current Scientific Reports (2045-2322) natureportfolio

Mentoring / Tutoring

Topic Student name
2024/03/05 - 2024/05/31 Avaliação do potencial neuroprotetor e antimicrobiano do extrato hidroalcoólico de Hymenaea courbaril L. (jatobá) em modelos in vitro e in vivo Larissa Lobo
2024/01 - 2024/05/31 Bioprospecção de microalgas com potencial bioativo antimicrobiano, antioxidante, citotóxico e anti-inflamatório Édina Blasi
2022/09 - 2024/05 Estudo dos efeitos de composto de origem marinha no crescimento de microrganismos da pele Andreia São Pedro
2023/11 - 2024/02 Efeito neuroprotetor de compostos bioativos isolados de algas Cindy Dávalos Quintana

Scientific expedition

Activity description Institution / Organization
2023/12/11 - 2023/12/21 Visiting researcher in the Medical University of Lodz (Poland) in the Prof. Renata Perlikowska research group. Evaluation of the neuroprotective potential using the human neuroblastom cells (SH-SY5Y cell line). Uniwersytet Medyczny w Lodzi, Poland