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Liliana Rodrigues is an Assistant Professor at the Unit of Medical Microbiology of IHMT-NOVA and member of the "TB, HIV and opportunistic diseases and pathogens (THOP)" group of Global Health and Tropical Medicine (GHTM) R&D center, and of the Associated Laboratory "REAL - Associated Laboratory in Translation and Innovation Towards Global Health". She holds a degree in Biology (Faculty of Sciences, Universidade de Lisboa, 2002), a MSc in Medical Microbiology (NOVA University of Lisbon, 2006) and a PhD in Biomedical Sciences, specialization Microbiology (IHMT-NOVA, 2010). She was involved in several research projects in the areas of drug discovery & resistance, including the FP7 project "More Medicines for Tuberculosis" (team member, 2011-2016), the Marie Sklodowska-Curie Actions Individual Fellowship "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis" (principal investigator, 2018-2020) and GHTM's Exploratory project "DrugsForNg: Study of the activity of repurposed drugs against Neisseria gonorrhoeae" (principal investigator, 2022-2023). Liliana Rodrigues teaches in several curricular units of the MSc and PhD programs of IHMT-NOVA. She also supervises several MSc and PhD students and participated in several thesis examination committees. Presently, her research focuses mainly on: molecular diagnostics of sexually transmitted infections; drug resistance mechanisms in N. gonorrhoeae and Mycoplasma genitalium; and in silico repurposing to find new drugs against N. gonorrhoeae and other clinically relevant pathogens.
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Identification

Personal identification

Full name
Liliana Rodrigues
Gender
Female

Citation names

  • Rodrigues, L

Author identifiers

Ciência ID
5618-CB13-BB18
ORCID iD
0000-0002-2094-2666
Researcher Id
N-2463-2014
Scopus Author Id
57200565603

Addresses

  • Unidade de Microbiologia Médica, Instituto de Higiene e Medicina Tropical. Rua da Junqueira 100, 1349-008, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Infectious Diseases
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Upper intermediate (B2)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2010
Concluded
 Ciências Biomédicas (Doutoramento)
Major in Microbiology
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"The Role of the Efflux Mechanisms in Multidrug Resistance in Mycobacterium Tuberculosis" (THESIS/DISSERTATION)
2006
Concluded
 Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"Diagnóstico precoce da tuberculose multirresistente em Lisboa" (THESIS/DISSERTATION)
 Thesis - Very Good (max grade)
2002
Concluded
 Biologia Microbiana e Genética (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 15/20
Affiliation

Science

Category
Host institution 		Employer
2018/09/01 - 2020/08/31 Contracted Researcher (Research) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2011/11/17 - 2016/07/31 Postdoc (Research) Universidad de Zaragoza Departamento de Microbiología Medicina Preventiva y Salud Pública, Spain
2013/01/01 - 2014/12/31 Researcher (Research) Fundación Agencia Aragonesa para la Investigación y Desarrollo (ARAID), Spain

Teaching in Higher Education

Category
Host institution 		Employer
2022/01/01 - Current Assistant Professor (University Teacher) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Other Careers

Category
Host institution 		Employer
2020/12/01 - 2021/12/31 Técnico Superior (Técnico Superior) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Others

Category
Host institution 		Employer
2018/09/01 - 2020/08/31 Marie Curie fellow (H2020-MSCA-IF-2017) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2006/03/01 - 2010/10/25 Ph.D. student (SFRH/BD/24931/2005) Universidade Nova de Lisboa, Portugal
2003/10/01 - 2006/02/21 Master's student of the Master's Course in Medical Microbiology Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projects

Grant

Designation Funders
2018/09/01 - 2020/08/31 Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis (iCHEMGENODRUGS_TB)
795924
Principal investigator
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluded

Contract

Designation Funders
2023/01/01 - 2024/06/30 Explorando a inibição de efluxo para o combate à resistência aos antimicrobianos e a biofilmes em estafilococos
2022.07931.PTDC
Researcher
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2014 - 2016 Biomedical applications of AS-48: a protein with broad spectrum antimicrobial activity
JIUZ-2013-BIO-04
Researcher
Universidad de Zaragoza Departamento de Microbiología Medicina Preventiva y Salud Pública, Spain
 Ministerio de Economía y Competitividad
Concluded
2011 - 2016 More medicines for tuberculosis (MM4TB)
260872
Researcher
Universidad de Zaragoza Departamento de Microbiología Medicina Preventiva y Salud Pública, Spain
 European Commission Seventh Framework Programme for Research and Technological Development
Concluded
2012/03/12 - 2015/09/30 NADH-menaquinona desidrogenase do tipo II (NDH-2) e a cadeia respiratória de M. tuberculosis: novos alvos terapêuticos no combate à tuberculose.
PTDC/BIA-MIC/121859/2010
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2014 - 2015 Characterization of compounds active against mycobacteria
N.A.
Principal investigator
Universidad de Zaragoza Departamento de Microbiología Medicina Preventiva y Salud Pública, Spain
 SOCIEDADE TECNICO-MEDICINAL, S.A. (TECNIMEDE)
Concluded
2014 - 2015 Study of the activity of efflux pumps of Mycobacterium tuberculosis in a Escherichia coli model
N.A.
Principal investigator
Universidad de Zaragoza Departamento de Microbiología Medicina Preventiva y Salud Pública, Spain
 Universidad de Zaragoza Departamento de Microbiología Medicina Preventiva y Salud Pública
Concluded
2011/01/01 - 2013/12/31 Projecto Estratégico - UI 74 - 2011-2012
PEst-OE/SAU/UI0074/2011
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2013 Enhancing the killing of intracellular multi-drug resistant tuberculosis (MDRTB) by human macrophages: a new chemotherapeutic strategy to fight MDRTB
PTDC/SAU-FCF/102807/2008
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
2010 - 2013 Helper compounds against multidrug resistant bacteria: revealing their mechanism of action
PTDC/BIA-MIC/105509/2008
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
2008 - 2011 Mutational and physiological dynamics of drug resistance in M. tuberculosis: the emergence of Multi-Drug Resistant Tuberculosis
PTDC/BIA-MIC/71280/2006
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
2007 - 2010 Efflux pumps in drug resistance of M. tuberculosis: Molecular characterization of the efflux mechanism and use of efflux inhibitors as new anti-tubercular compounds
PPCDT/SAU-MMO/59370/2004
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia

Other

Designation Funders
2022 - 2023 DrugsForNg: Study of the activity of repurposed drugs against Neisseria gonorrhoeae: targeting membrane transport and energy metabolism
-
Principal investigator
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
 Universidade Nova de Lisboa Saúde Global e Medicina Tropical
Concluded
Outputs

Publications

Book chapter
  1. Rodrigues, Liliana; Aínsa, José A.; Viveiros, Miguel. "Measuring Efflux and Permeability in Mycobacteria". In Mycobacteria Protocols. United States: Springer, 2021.
    Published
  2. Rodrigues L; Viveiros M; Aínsa JA. "Measuring efflux and permeability in mycobacteria.". In Methods in molecular biology (Clifton, N.J.). 2015.
    Published • 10.1007/978-1-4939-2450-9_13
  3. Amaral, L.; Martins, A.; Spengler, G.; Martins, M.; Rodrigues, L.; McCusker, M.; Ntokou, E.; et al. "Structure, genetic regulation, physiology and function of the AcrAB-TolC efflux pump of Escherichia coli and Salmonella.". In Antimicrobial drug discovery: emerging strategies, 44-61. United States: CABI, 2012.
    10.1079/9781845939434.0044
  4. Amaral L; Fanning S.; Spengler G; Rodrigues, Liliana; Iversen C; Martins M; Martins A; Viveiros M; Couto I. "Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens". Nova Science Publishers, 2012.
    Published
  5. Amaral, L; Viveiros, Miguel; Fanning, S.; Pages JM; couto isabel; Spengler, G.; Rodrigues, Liliana; Martins, A.. "Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens". 313-332. New York, United States: Nova Science Publishers, 2011.
    Published
  6. Amaral L; Fanning S; McCusker M; Spengler G; Rodrigues, Liliana; Iversen C; Martins M; et al. "Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens". Nova Science Publishers, 2010.
Conference abstract
  1. Rodrigues, L; Cravo, Pedro Vitor Lemos; Viveiros, Miguel. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis through in silico drug repurposing". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2020.
  2. Amaral, L; Spengler, G; Viveiros, M; Rodrigues, L; Martins, A; Couto, I; Martins, M; et al. "ASSESSMENT AND COMPARISON OF EFFLUX PUMPS OF CANCER CELLS AND MDR BACTERIA UNDER PHYSIOLOGICAL CONDITIONS BY A REAL-TIME SEMI-AUTOMATED SYSTEM". 2008.
  3. Spengler, G; Viveiros, M; Martins, A; Rodrigues, L; Martins, M; Molnar, J; Couto, I; Amaral, L. "DEMONSTRATION OF THE ACTIVITY OF P-GLYCOPROTEIN BY A FULLY AUTOMATED ETHIDIUM BROMIDE METHOD". 2008.
Conference poster
  1. Marques, Débora; Sofia Santos Costa; SS Costa; S Santos Costa; Rodrigues, L. Corresponding author: Rodrigues, L. "Identification of efflux inhibitors for Candida albicans through a drug repurposing strategy". Paper presented in Gordon Research Conference on Multi-Drug Efflux Systems: Navigating Efflux Proteins through Fundamental Research and Clinical Translation, 2025.
  2. D615-9B80-66C9; André Pina; Beatriz Santos; Inês Vítor; Ana Henriques; Filomena Pereira 301A-F230-0228; Couto, Isabel; et al. Corresponding author: Rodrigues, L. "Targeting membrane transport and energy metabolism for the identification of new drugs for Neisseria gonorrhoeae using in silico repurposing". Paper presented in Gordon Research Conference on Multi-Drug Efflux Systems: Navigating Efflux Proteins through Fundamental Research and Clinical Translation, 2025.
  3. Andrade, Mariana; Joana Neves; Maria Bento; Joana Palma-Marques; Seabra, Sofia; Viveiros, Miguel; Rodrigues, L; et al. "Evaluation of candidate drugs for repurposing in a Galleria mellonella staphylococcal infection model". Paper presented in ESCMID Global 2025, 2025.
  4. Santos, B.; Ana Armada; Rodrigues, L. Corresponding author: Rodrigues, L. "Evaluation of toxicity and efflux inhibitory activity of candidate drugs for repurposing against Neisseria gonorrhoeae". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2024.
  5. Rusu A.; Filomena Pereira 301A-F230-0228; Rodrigues, L. Corresponding author: Rodrigues, L. "Identification of Mycoplasma genitalium and characterisation of mutations associated with macrolide and fluoroquinolone resistance in a population from the Lisbon area, Portugal". Paper presented in MicroBiotec23, 2023.
  6. Santos B.; Armada A.; Rodrigues, L. Corresponding author: Rodrigues, L. "Evaluation of toxicity and in vitro activity of candidate drugs for repurposing against Neisseria gonorrhoeae". Paper presented in MicroBiotec23, 2023.
  7. Rodrigues, Telma; Andrade, Mariana; Marques, Joana; Rodrigues, L; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; Costa, Sofia Santos. "Implementation of a Galleria mellonella infection model at GHTM/IHMT-NOVA". Paper presented in MicroBiotec23, 2023.
  8. Neves, Joana; Antunes, Carolina; Andrade, Mariana; Bento, Maria; Couto, Isabel; Rodrigues, L; Costa, Sofia Santos. "Drug repurposing for identification of new efflux inhibitors and/or antibiofilm agents against Staphylococcus aureus and Staphylococcus". Paper presented in MicroBiotec23, 2023.
  9. Rusu A.; Filomena Pereira 301A-F230-0228; Rodrigues, L. Corresponding author: Rodrigues, L. "Identification of Mycoplasma genitalium and characterisation of mutations associated with macrolide and fluoroquinolone resistance in a population from the Lisbon area, Portugal". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2023.
  10. Mendes A; Sofia Santos Costa; SS Costa; S Santos Costa; Rodrigues, L. "Evaluation of the activity of repurposed drugs that target energy metabolism in Escherichia coli". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2023.
  11. Pina A.; Filomena Pereira 301A-F230-0228; Rodrigues, L. Corresponding author: Rodrigues, L. "Targeting membrane transport and energy metabolism for the identification of new drugs for Neisseria gonorrhoeae". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2022.
  12. Pina A.; Filomena Pereira 301A-F230-0228; Rodrigues, L. Corresponding author: Rodrigues, L. "Identification of new drugs for Neisseria gonorrhoeae using an in silico repurposing strategy". Paper presented in Microbiotec21, 2021.
  13. Bento-Cunha, Renata; Tatiana Vassilevskaia; Rodrigues, L; Viveiros, Miguel; Cunha, Celso. "Repsitioning drugs with potential activity against SARS-CoV-2 infection.". Paper presented in Microbiotec21, 2021.
  14. Pina A; Filomena Pereira 301A-F230-0228; Rodrigues, L. Corresponding author: Rodrigues, L. "Identification of new drugs for Neisseria gonorrhoeae using an in silico repurposing strategy". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2021.
  15. Rodrigues, L; Cravo, Pedro Vitor Lemos; Viveiros, Miguel. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis through in silico drug repurposing". Paper presented in II Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal Universidade de Lisboa Faculdade de Farmácia, Portugal, 2020.
  16. Rodrigues, L; Cravo, Pedro Vitor Lemos; Viveiros, Miguel. "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis". Paper presented in Gordon Research Conference on Multi-Drug Efflux Systems, 2019.
Journal article
  1. Andrade, Mariana; Neves, Joana; Bento, Maria; Marques, Joana; Seabra, Sofia G.; Silveira, Henrique; Rodrigues, Liliana; et al. "Evaluation of Amlodipine and Imipramine Efficacy to Treat Galleria mellonella Infection by Biofilm-Producing and Antimicrobial-Resistant Staphylococcus aureus". Antibiotics 14 2 (2025): 183. https://doi.org/10.3390/antibiotics14020183.
    10.3390/antibiotics14020183
  2. Débora Marques; Sofia Santos Costa; SS Costa; S Santos Costa; Rodrigues, Liliana. "Identification of efflux inhibitors through a drug repurposing strategy in Candida albicans". In the last stages of preparation to be submitted to Frontiers in Cellular and Infection Microbiology (2025):
  3. Pereira, Inês A.; André Pina; Beatriz Santos; Inês Vítor; Ana Henriques; João Fernandes; Filomena Pereira 301A-F230-0228; et al. "Targeting membrane transport and energy metabolism for the identification of new drugs for Neisseria gonorrhoeae using an in silico repurposing strategy". In the last stages of preparation to be submitted to Antibiotics (2025):
  4. Barros, Margarida; Filomena Pereira 301A-F230-0228; Rodrigues, L. "Molecular characterization of antimicrobial resistance and genotyping of Mycoplasma genitalium positive samples of the Lisbon area, Portugal". In the last stages of preparation to be submitted to BMC Infectious Diseases (2025):
  5. Rodrigues, Liliana; Bento-Cunha, Renata; Tatiana Vassilevskaia; Viveiros, Miguel; Cunha, Celso . Corresponding author: Rodrigues, Liliana. "Drug repurposing for COVID-19: a review and a novel strategy to identify new targets and potential drug candidates". Molecules 27 9 (2022): 2723. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099573/.
    Published
  6. Rodrigues, Liliana; Cravo, Pedro Vitor Lemos; Viveiros, Miguel. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs". Expert Review of Anti-infective Therapy (2020): https://doi.org/10.1080/14787210.2020.1760845.
    Published
  7. Salillas, Sandra; Alías, Miriam; Michel, Valérie; Mahía, Alejandro; Lucía, Ainhoa; Rodrigues, Liliana; Bueno, Jessica; et al. "Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice". Journal of Medicinal Chemistry 62 13 (2019): 6102-6115. http://dx.doi.org/10.1021/acs.jmedchem.9b00355.
    10.1021/acs.jmedchem.9b00355
  8. Sanz-García, Fernando; Anoz-Carbonell, Ernesto; Pérez-Herrán, Esther; Martín, Carlos; Lucía, Ainhoa; Rodrigues, Liliana; Aínsa, José A.. "Mycobacterial Aminoglycoside Acetyltransferases: A Little of Drug Resistance, and a Lot of Other Roles". Frontiers in Microbiology 10 (2019): http://dx.doi.org/10.3389/fmicb.2019.00046.
    Open access • Published • 10.3389/fmicb.2019.00046
  9. Vieira ML; Rodrigues, Liliana; Almeida F; Fortes F; de Sousa G; Monteiro S.; Henrique H; Viveiros, Miguel. "Laboratory services contribution to supporting public health and health services in Portuguese-speaking countries". Anais do Instituto de Higiene e Medicina Tropical (2019): https://doi.org/10.25761/anaisihmt.337.
    Published
  10. Mori, Giorgia; Orena, Beatrice Silvia; Franch, Clara; Mitchenall, Lesley A.; Godbole, Adwait Anand; Rodrigues, Liliana; Aguilar-Pérez, Clara; et al. "The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase". Tuberculosis 112 (2018): 98-109. http://dx.doi.org/10.1016/j.tube.2018.08.004.
    10.1016/j.tube.2018.08.004
  11. García, María T.; Carreño, David; Tirado-Vélez, José M.; Ferrándiz, María J.; Rodrigues, Liliana; Gracia, Begoña; Amblar, Mónica; Ainsa, José A.; de la Campa, Adela G.. "Boldine-Derived Alkaloids Inhibit the Activity of DNA Topoisomerase I and Growth of Mycobacterium tuberculosis". Frontiers in Microbiology 9 (2018): http://dx.doi.org/10.3389/fmicb.2018.01659.
    10.3389/fmicb.2018.01659
  12. Aguilar-Pérez, Clara; Gracia, Begoña; Rodrigues, Liliana; Vitoria, Asunción; Cebrián, Rubén; Deboosère, Nathalie; Song, Ok-ryul; et al. "Synergy between Circular Bacteriocin AS-48 and Ethambutol against Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy 62 9 (2018): http://dx.doi.org/10.1128/aac.00359-18.
    10.1128/aac.00359-18
  13. Glaus, Florian; Dedic, Darija; Tare, Priyanka; Nagaraja, Valakunja; Rodrigues, Liliana; Aínsa, José Antonio; Kunze, Jens; et al. "Total Synthesis of Ripostatin B and Structure–Activity Relationship Studies on Ripostatin Analogs". The Journal of Organic Chemistry 83 13 (2018): 7150-7172. http://dx.doi.org/10.1021/acs.joc.8b00193.
    10.1021/acs.joc.8b00193
  14. Rodrigues L; Parish T; Balganesh M; Ainsa JA. "Antituberculosis drugs: reducing efflux=increasing activity.". Drug discovery today (2017): http://europepmc.org/abstract/med/28089787.
    10.1016/j.drudis.2017.01.002
  15. Singh V; Dhar N; Pató J; Kolly GS; Korduláková J; Forbak M; Evans JC; et al. "Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.". Molecular microbiology (2017): http://europepmc.org/abstract/med/27677649.
    10.1111/mmi.13535
  16. Rodrigues L; Villellas C; Bailo R; Viveiros M; Aínsa JA. "Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.". Antimicrobial agents and chemotherapy (2013): http://europepmc.org/abstract/med/23165464.
    10.1128/aac.01482-12
  17. Viveiros M; Martins M; Rodrigues L; Machado D; Couto I; Ainsa J; Amaral L. "Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.". Expert review of anti-infective therapy (2012): http://europepmc.org/abstract/med/23106274.
    10.1586/eri.12.89
  18. Rodrigues L; Machado D; Couto I; Amaral L; Viveiros M. "Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex.". Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases (2012): http://europepmc.org/abstract/med/21871582.
    10.1016/j.meegid.2011.08.009
  19. Spengler G; Rodrigues L; Martins A; Martins M; McCusker M; Cerca P; Machado L; et al. "Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent.". International journal of antimicrobial agents (2012): http://europepmc.org/abstract/med/21982147.
    10.1016/j.ijantimicag.2011.08.013
  20. Machado D; Couto I; Perdigão J; Rodrigues L; Portugal I; Baptista P; Veigas B; Amaral L; Viveiros M. "Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.". PloS one (2012): http://europepmc.org/abstract/med/22493700.
    10.1371/journal.pone.0034538
  21. Rodrigues L; Aínsa JA; Amaral L; Viveiros M. "Inhibition of drug efflux in mycobacteria with phenothiazines and other putative efflux inhibitors.". Recent patents on anti-infective drug discovery (2011): http://europepmc.org/abstract/med/21517739.
    10.2174/157489111796064579
  22. Rodrigues L; Ramos J; Couto I; Amaral L; Viveiros M. "Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.". BMC microbiology (2011): http://europepmc.org/abstract/med/21332993.
    10.1186/1471-2180-11-35
  23. Martins A; Spengler G; Martins M; Rodrigues L; Viveiros M; Davin-Regli A; Chevalier J; et al. "Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes.". International journal of antimicrobial agents (2010): http://europepmc.org/abstract/med/20688487.
    10.1016/j.ijantimicag.2010.06.036
  24. Couto I; Machado D; Viveiros M; Rodrigues L; Amaral L. "Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a 3-year study.". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2010): http://europepmc.org/abstract/med/19832711.
    10.1111/j.1469-0691.2009.03076.x
  25. Viveiros M; Martins M; Couto I; Rodrigues L; Machado D; Portugal I; Amaral L. "Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.". Expert review of anti-infective therapy (2010): http://europepmc.org/abstract/med/20377340.
    10.1586/eri.10.20
  26. Amaral L; Martins A; Molnar J; Kristiansen JE; Martins M; Viveiros M; Rodrigues L; et al. "Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB.". In vivo (Athens, Greece) (2010): http://europepmc.org/abstract/med/20668307.
  27. Viveiros M; Rodrigues L; Martins M; Couto I; Spengler G; Martins A; Amaral L. "Evaluation of efflux activity of bacteria by a semi-automated fluorometric system.". Methods in molecular biology (Clifton, N.J.) (2010): http://europepmc.org/abstract/med/20401593.
    10.1007/978-1-60327-279-7_12
  28. Rodrigues L; Sampaio D; Couto I; Machado D; Kern WV; Amaral L; Viveiros M. "The role of efflux pumps in macrolide resistance in Mycobacterium avium complex.". International journal of antimicrobial agents (2009): http://europepmc.org/abstract/med/19740629.
    10.1016/j.ijantimicag.2009.07.010
  29. Martins A; Iversen C; Rodrigues L; Spengler G; Ramos J; Kern WV; Couto I; et al. "An AcrAB-mediated multidrug-resistant phenotype is maintained following restoration of wild-type activities by efflux pump genes and their regulators.". International journal of antimicrobial agents (2009): http://europepmc.org/abstract/med/19734019.
    10.1016/j.ijantimicag.2009.06.029
  30. Spengler G; Viveiros M; Martins M; Rodrigues L; Martins A; Molnar J; Couto I; Amaral L. "Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method.". Anticancer research (2009): http://europepmc.org/abstract/med/19528478.
  31. Martins A; Spengler G; Rodrigues L; Viveiros M; Ramos J; Martins M; Couto I; et al. "pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon.". PloS one (2009): http://europepmc.org/abstract/med/19684858.
    10.1371/journal.pone.0006656
  32. Paixão L; Rodrigues L; Couto I; Martins M; Fernandes P; de Carvalho CC; Monteiro GA; et al. "Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli.". Journal of biological engineering (2009): http://europepmc.org/abstract/med/19835592.
    10.1186/1754-1611-3-18
  33. Spengler G; Martins A; Schelz Z; Rodrigues L; Aagaard L; Martins M; Costa SS; et al. "Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method.". In vivo (Athens, Greece) (2009): http://europepmc.org/abstract/med/19368129.
  34. Viveiros M; Martins M; Couto I; Rodrigues L; Spengler G; Martins A; Kristiansen JE; Molnar J; Amaral L. "New methods for the identification of efflux mediated MDR bacteria, genetic assessment of regulators and efflux pump constituents, characterization of efflux systems and screening for inhibitors of efflux pumps.". Current drug targets (2008): http://europepmc.org/abstract/med/18781922.
    10.2174/138945008785747734
  35. Rodrigues L; Wagner D; Viveiros M; Sampaio D; Couto I; Vavra M; Kern WV; Amaral L. "Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis.". The Journal of antimicrobial chemotherapy (2008): http://europepmc.org/abstract/med/18310137.
    10.1093/jac/dkn070
  36. Viveiros M; Martins A; Paixão L; Rodrigues L; Martins M; Couto I; Fähnrich E; Kern WV; Amaral L. "Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method.". International journal of antimicrobial agents (2008): http://europepmc.org/abstract/med/18343640.
    10.1016/j.ijantimicag.2007.12.015
  37. Viveiros M; Dupont M; Rodrigues L; Couto I; Davin-Regli A; Martins M; Pagès JM; Amaral L. "Antibiotic stress, genetic response and altered permeability of E. coli.". PloS one (2007): http://europepmc.org/abstract/med/17426813.
    10.1371/journal.pone.0000365
  38. Viveiros M; Leandro C; Rodrigues L; Almeida J; Bettencourt R; Couto I; Carrilho L; et al. "Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis.". Journal of clinical microbiology (2005): http://europepmc.org/abstract/med/16145166.
    10.1128/jcm.43.9.4880-4884.2005
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/04/12 Identification of efflux inhibitors for Candida albicans through a drug repurposing strategy ESCMID Global 2025
(Viena, Austria)
2025/04/12 Molecular characterization of antimicrobial resistance and genotyping of Mycoplasma genitalium positive samples of the Lisbon area, Portugal ESCMID Global 2025
(Viena, Austria)
2024/04 New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant Staphylococcus aureus and Staphylococcus epidermidis European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
European Society of Clinical Microbiology and Infectious Diseases (Barcelona, Spain)
2024/03 The role of efflux pumps in antimicrobial resistance in Neisseria gonorrhoeae clinical isolates II Congresso da Associação Portuguesa de Ciências Biomédicas Laboratoriais- BioMedLab
Associação Portuguesa de Ciências Biomédicas Laboratoriais (Coimbra, Portugal)
2023/04 Drug repurposing as an approach to bypass efflux-mediated resistance in Neisseria gonorrhoeae Congresso Nacional de Medicina Tropical
Universidade Nova de Lisboa, Instituto de Higiene e Medicina Tropical (Lisbon, Portugal)
2020/11/19 Drug repurposing in M. tuberculosis. Fourth GHTM Antimicrobial Resistance Awareness Day
Global Health and Tropica Medicine-IHMT-NOVA (Lisbon, Portugal)
2019/09/20 In silico repurposing of approved drugs against tuberculosis: targeting membrane transporters and energy metabolism. MycoPorto2019
Insituto de Ciências Biomédicas Abel Salazar (ICBAS) (Porto, Portugal)
2019/07/10 Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis Encontro Ciência 2019
(Lisboa, Portugal)
2017 New strategies to fight MDR-TB: from early detection to innovative drug discovery MiniSymposium: Looking for new ways to fight tuberculosis
ITQB (Oeiras, Portugal)
2017 Efflux studies integrated in a tuberculosis drug discovery program GHTM sessions
IHMT (Lisboa, Portugal)
2013 Targeting multidrug efflux pumps in Mycobacterium tuberculosis MycoSpain
(Bilbao, Spain)
2012 Testing new compounds against M. tuberculosis. MycoSpain
(Madrid, Spain)
2012 Novel compounds active against Mycobacterium tuberculosis: testing competitive inhibitors of type II dehydroquinase. V International Conference BIFI 2012
(Zaragoza, Spain)
2010 Contribution of the Mmr efflux pump to antimicrobial resistance in M. tuberculosis: construction of a mmr knockout mutant by allelic exchange Cost Action BM0701, WG1 meeting
Cost Action BM0701 (Bremen, Germany)
2009 Characterization of efflux pumps of mycobacteria by real-time RT-PCR and a semi-automated fluorometric method Cost Action BM0701, WG1 meeting
Cost Action BM0701 (Dublin, Ireland)
2009 Efflux pumps in Escherichia coli and Mycobacterium sp.: Methods to assess their importance in multidrug resistance URIA Mycobacterium Workshop
Faculdade de Farmácia, Univerdade de Lisboa (Lisboa, Portugal)
2009 Contribution of effflux pump activity for macrolide resistance in M. avium complex. 30th Annual Congress of the European Society of Mycobacteriology (ESM)
ESM (Porto, Portugal)
2008 The role of efflux pumps in drug resistance. Journal Club
IHMT (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024 - Current Characterization of the molecular resistance profile and phylogenetic analysis of Neisseria gonorrhoeae
Supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024 - Current Identification of drugs for repurposing as efflux inhibitors and/or antibiofilm agents against clinically-relevant pathogens
Co-supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024 - Current Targeting efflux mechanisms in Neisseria gonorrhoeae: exploring drug repurposing as a strategy against antimicrobial resistance
Supervisor
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023 - Current Molecular Detection of Aflatoxigenic Fungi in Agricultural Products from the Main Agroecologies of Mozambique.
Co-supervisor
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/09 - 2025/03/27 Identification of efflux inhibitors in Candida albicans using a drug repurposing strategy
Supervisor
 Medical Microbiology (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/09 - 2025/03/13 Molecular characterization of antimicrobial resistance and genotyping of Mycoplasma genitalium-positive samples of the Lisbon area
Supervisor
 Medical Microbiology (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/09 - 2025 Evaluation of the activity and efficacy of drugs for repurposing against Staphylococcus aureus and Staphylococcus epidermidis
Co-supervisor
 Medical Microbiology (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022 - 2024 Assessment of toxicity and in vitro activity of phenothiazines and verapamil on Neisseria gonorrhoeae
Supervisor
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022 - 2024 Assessment of toxicity and in vitro activity of candidate drugs for repositioning against Neisseria gonorrhoeae
Supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022 - 2024 The role of efflux pumps in antimicrobial resistance in clinical isolates of Neisseria gonorrhoeae.
Supervisor
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022 - 2024 Evaluation of the in vitro activity of amlodipine and other ion channel blockers on Neisseria gonorrhoeae
Supervisor
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09 - 2023 Evaluation of the antimicrobial activity of compounds that inhibit energy metabolism in Gram-negative bacteria.
Supervisor
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09 - 2023 Drug repositioning to decrease resistance mediated by efflux pumps in Neisseria gonorrhoeae and other Gram-negative bacteria.
Supervisor
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09 - 2023 Identification of Mycoplasma genitalium and detection of resistance to azithromycin in a population of men who have sex with men
Supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09 - 2023 New therapeutic approaches against Staphylococcus aureus: use of chemogenomics to identify new drugs against efflux and biofilms
Co-supervisor
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09 - 2023 New therapeutic approaches against Staphylococcus epidermidis: use of chemogenomics to identify new drugs against efflux and biofilms
Co-supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09 - 2023 Characterization of the genetic diversity of circulating vhb in the cities of Luanda and Benguela (Angola)
Co-supervisor
 Saúde Tropical (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020/09 - 2022/02 Identification of new drugs for Neisseria gonorrhoeae using an in silico repurposing strategy.
Supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa, Portugal
2021/03 - 2021/06 Evaluation of the activity of efflux pump inhibitors in Neisseria gonorrhoeae.
Supervisor
 BSc Cell and Molecular Biology (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2015 Caracterización de genes de resistencia a antibióticos de micobacterias
Co-supervisor
 Biotecnologia (Degree)
Universidad de Zaragoza, Spain
2013 - 2014 Estudio de la actividad de bombas de eflujo de Mycobacterium tuberculosis en un modelo de Escherichia coli
Co-supervisor
 Biología Molecular y Celular (Master)
Universidad de Zaragoza, Spain
2013 - 2014 Caracterización genética del gen Rv1258c en cepas de Mycobacterium tuberculosis de la familia Beijing
Co-supervisor
 Biotecnologia (Degree)
Universidad de Zaragoza, Spain

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/10/20 - 2023/10/20 Conference NOVA Health Chronic Disease and Infection: Challenges of vaccination throughout life (2023/10/20 - 2023/10/20)
Conference (Member of the Organising Committee)
 Universidade Nova de Lisboa, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/09/27 - Current "Super Bugs": This activity had the aim to raise the community’s awareness about antimicrobial resistance and how drug repurposing can be used to fight this problem and contribute to a sustainable development and improvement of the quality of life.
Exhibition
 European Researchers' Night
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2019/09/27 - 2019/09/27 Antimicrobial resistance: role of biocides and new ways to fight Bacterial “Super Villains”. The objective was to raise the community’s awareness about non-antibiotic (biocides: antiseptics and disinfectants) antimicrobial resistance and how drug repurposing can be used to fight this problem and contribute to a sustainable development and improvement of the quality of life.
Exhibition
 European Researchers Night
Universidade de Lisboa Museu Nacional de História Natural, Portugal
2019/09/17 - 2019/09/17 Did you know that antimicrobial resistance is not just about antibiotics and that old drugs can be repurposed to fight resistant bacteria? The aim of this activity was to raise the community's awareness about non-antibiotic (biocides: antiseptics and disinfectants) antimicrobial resistance and how drug repurposing can be used to fight this problem and contribute to the improvement of the quality of life.
Exhibition
 Microorganism Day
2012 - 2016 MM4TB project consorcium meetings that took place twice a year. Oral presentations of results were carried out in these meetings.
Meeting
 Consorcium meeting
FP 7 consorcium - More Medicines for Tuberculosis (MM4TB), Switzerland
2015 - 2015 Laboratory animal course: Category C (persons responsible for directing animal experiments)
Other
 Laboratory animal course: Category C (persons responsible for directing animal experiments)
Universidad de Zaragoza, Spain
2014/05 - 2014/05 Poster: Fuentes D., Villellas C., Vitoria MA, Samper S., Aínsa JA, Rodrigues L. A simple method based on a reliable genetic marker for identification of Mycobacterium tuberculosis Beijing genotype.
Congress
 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2013 - 2013 Theoretical-practical training in Biosafety and use of level 3 biosafety laboratories (BSL3)
Other
Universidad de Zaragoza, Spain
2012/11 - 2012/11 Poster: Rodrigues L., et al. Contribución de la bomba de eflujo Mmr a la resistencia a fármacos en M. tuberculosis.
Congress
 IX Reunión del Grupo de Microbiología Molecular
2012/09 - 2012/09 Poster: Rodrigues L., et al. Is the Mmr Efflux Pump of M. tuberculosis Involved in Isoniazid Resistance?
Congress
 Tuberculosis 2012: Biology, pathogenesis, intervention, strategies. París, France
Institut Pasteur, France
2012/03 - 2012/03 Poster: Machado D., Rodrigues L., et al. The emergence of clarithromycin resistance in Mycobacterium avium complex.
Congress
 22nd European Congress of Clinical Microbiology and Infectious Diseases.
European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2011/04 - 2011/04 Poster: Rodrigues L., et al. Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.
Conference
 Gordon Research Conference on Multi-Drug Efflux Systems: From Molecular Mechanisms to Pharmacological Modulation
2011 - 2011 Poster: Machado D., Couto I., Rodrigues L., et al. Efflux activity in Mycobacterium tuberculosis as an intrinsic mechanism of resistance to isoniazid
Congress
 32th Annual Congress of the European Society of Mycobacteriology
2010/07/04 - 2010/07/10 Poster: "Transport across membranes: multiple drug resistance, mechanism and new tools".
Seminar
 462th WE Heraeus Seminar "Transport across membranes: multiple drug resistance, mechanism and new tools".
Jacobs University of Bremen, Germany
2010/07 - 2010/07 Poster: Rodrigues L., et al. Contribution of efflux activity to isoniazid resistance in Mycobacterium tuberculosis complex.
Conference
 462th WE Heraeus Seminar: Transport across membranes: multiple drug resistance, mechanism and new tools
Jacobs University of Bremen, Germany
2010/05 - 2010/05 Poster: Machado D., Couto I., Rodrigues L., et al. Phenotypic adaptation to isoniazid in Mycobacterium tuberculosis: The contribution for the emergence of multidrug resistant tuberculosis
Congress
 21th European Congress of Clinical Microbiology and Infectious Diseases and 27th International Congress of Chemotherapy (ICC)
European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2010/05 - 2010/05 Poster: Rodrigues L., et al. Contribution of efflux activity to isoniazid resistance in Mycobacterium tuberculosis complex.
Congress
 21th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) and 27th International Congress of Chemotherapy (ICC)
European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2009/12 - 2009/12 Poster: Ramos J., Rodrigues L., Couto I., Amaral L., Viveiros M. The effect of efflux pumps inhibitors on the transport of ethidium bromide and antimicrobials across Mycobacterium smegmatis cell wall.
Congress
 Microbiotec09
2009/12 - 2009/12 Poster: Rodrigues L., et al. The role played by efflux pumps in macrolide resistance in Mycobacterium avium complex
Congress
 Microbiotec09
2009/09/13 - 2009/09/18 Leeds Ion Channels Workshop
Workshop
 Leeds Ion Channels Workshop
2009/07 - 2009/07 Poster: Ramos J., Rodrigues L., et al. Methods for assessment of ethidium bromide transport across Mycobacterium smegmatis cell wall.
Congress
 30th Annual Congress of the European Society of Mycobacteriology
2008/04 - 2008/04 Poster: Rodrigues L., et al. Intrinsic drug resistance of M. avium-M. intracellulare complex: the role played by efflux pumps
Congress
 18th European Congress of Clinical Microbiology and Infectious Disease
European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2007/07 - 2007/07 Poster: Rodrigues L., et al. Antibiotic Stress, Genetic Response and Altered Permeability of E. coli.
Congress
 Summer School, Jacobs University of Bremen
Jacobs University of Bremen, Germany

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025/04/10 Untangling the link between iron and the activity of the antifungal drug caspofungin
(Thesis) Arguer
 Andreia Dóris Pedras Rodrigues (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2025/03/27 Identificação de inibidores de efluxo em Candida albicans através de uma estratégia de reposicionamento de fármmcos
Supervisor
 Débora Alexandra Dias Marques (Master)
Universidade Nova de Lisboa, Portugal
2025/03/13 Caracterização molecular da resistência aos antimicrobianos e genotipagem de mycoplasma genitalium em amostras positivas da área de Lisboa
Supervisor
 Margarida Rodrigues dos Santos Feliciano de Barros (Master)
Universidade Nova de Lisboa, Portugal
2024/01/16 Assessment of toxicity and in vitro activity of candidate drugs for repositioning against Neisseria gonorrhoeae
Supervisor
 Beatriz Santos (Master)
Universidade Nova de Lisboa, Portugal
2024 The role of efflux pumps in antimicrobial resistance in Neisseria gonorrhoeae clinical isolates
Supervisor
 Teresa Paulino (Master)
Universidade Nova de Lisboa, Portugal
2024 Evaluation of the in vitro activity of amlodipine and other ion channel blockers in Neisseria gonorrhoeae
Supervisor
 João Fernandes (Master)
Universidade Nova de Lisboa, Portugal
2023/12/06 Assessment of cytotoxicity and efflux inhibition activity of phenothiazines and verapamil in Neisseria gonorrhoeae
Supervisor
 Ana Henriques (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/10/23 New in vitro Point-of-Care Diagnostic Tests for Gonorrhea and Syphilis using the Doctor Vida® Pocket
(Thesis) Main arguer
 Ana Calheta (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/07 Experimental Validation of Pharmaceutical Drugs for repurposing as new efflux inhibitors in Staphylococcus aureus
(Thesis) Main arguer
 Benjamim Carvalho (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/05/09 Identification and characterization of the molecular resistance profile of Mycoplasma genitalium to macrolides and fluoroquinolones in a population of the Lisbon area
Supervisor
 Alexandra Rusu (Master)
Universidade Nova de Lisboa, Portugal
2023/02/08 Drug repositioning to reduce resistance mediated by efflux pumps in Neisseria gonorrhoeae and other Gram-negative bacteria
Supervisor
 Inês Lima Vítor (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023 Evaluation of the antimicrobial activity of compounds that inhibit energy metabolism in Escherichia coli
Supervisor
 Ana Mendes (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/06 Evaluation of the activity of efflux pump inhibitors in Neisseria gonorrhoeae.
Supervisor
 Maria João Veríssimo Almeida (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/01/22 Molecular and dynamic mechanisms of prokaryotic and eukaryotic flavoenzymes: insights into their implication in human metabolism and health
(Thesis) Arguer
 ERNESTO ANOZ CARBONELL (PhD)
Universidad de Zaragoza, Spain
2015 Characterization of the MmpL4/MmpS4 efflux system in Mycobacterium bovis and Mycobacterium tuberculosis
(Thesis) Arguer
 Rebeca Bailo Vergara (PhD)
Universidad de Zaragoza, Spain
2015 Desenvolvimento de novas estratégias metodológicas para avaliação de compostos com potencial terapêutico para a tuberculose e outras micobacterioses
(Thesis) Main arguer
 Elizeth do Rosário Delgados Lopes (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2013 A role of efflux pumps in intrinsic resistance and virulence of Mycobacterium tuberculosis
(Thesis) Arguer
 Maria Cristina Villellas Arilla (PhD)
Universidad de Zaragoza, Spain
2013 Novas estratégias no combate à tuberculose: a NADH-menaquinona desidrogenase do tipo II de Mycobacterium tuberculosis
(Thesis) Main arguer
 Carlos Filipe Serafim Serra (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Association member

Society Organization name Role
2020 - Current European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Member
2009 - Current Sociedade Portuguesa de Microbiologia Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023 - Current Curricular Unit: "Introduction to Medical Micology" Medical Microbiology: (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021 - Current Curricular Unit - Sexually Transmitted Infections Mestrado em Microbiologia Médica (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021 - Current Aplications in Medical Microbiology: Laboratory diagnosis of Neisseria goorrhoeae. Ciências Biomédicas (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020 - Current Curricular Unit - Tuberculosis and other mycobacteria (lecturer theroretical class) Curricular Unit - Antibiotics Resistance Mechanisms (lecturer theroretical class:) Microbiologia Médica (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2019/11/05 - Current Curricular Unit - Medical Bacteriology: Theoretical class - Gram-negative bacteria (I) Pratical class - Gram-negative bacteria: Enterobacteriaceae and other Gram-negative bacteria; Pratical class - Laboratory diagnosis of sexually transmitted infections. Microbiologia Médica (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2019 - Current Curricular Unit - General Microbiology: Theoretical class - Gram-negative bacteria; Pratical class - Identification of Gram-negative and Gram-positive bacteria. Mestrado em Ciências Biomédicas (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2022 - Current ECCMID abstracts reviewer
Evaluator
 European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2021 - Current ESCMID Research Grants
Evaluator
 European Society of Clinical Microbiology and Infectious Diseases, Switzerland

Journal scientific committee

Journal title (ISSN) Publisher
2025 - Current Currently Pharmacology Report Springer Nature
2025 - Current Annals of Clinical Microbiology and Antimicrobials BMC - Springer Nature
2021/01 - 2021 Microbial Pathogenesis (0882-4010) Elsevier
2021 - 2021 Antimicrobial Agents and Chemotherapy (1098-6596)
2019/06 - 2020/12 Frontiers in Microbiology (1664-302X) Frontiers Media SA
2020 - 2020 Molecules (1420-3049) MDPI AG
2020 - 2020 Antimicrobial Agents and Chemotherapy (1098-6596) American Society for Microbiology
2019 - 2019 Tuberculosis (1472-9792) Elsevier
2018 - 2018 Infection Genetics and Evolution (1567-1348) Elsevier
2018 - 2018 Evidence-based Complementary and Alternative Medicine (1741-4288) Hindawi Limited
2015 - 2015 Journal of Pathogens (2090-3065) Hindawi Limited
2013 - 2013 BioMed Research International
2012 - 2013 Diagnostic Microbiology and Infectious Disease (0732-8893) Elsevier
2012 - 2012 Antimicrobial Agents and Chemotherapy (1098-6596) American Society for Microbiology
2011 - 2011 Veterinary Microbiology (0378-1135) Elsevier

Other jury / evaluation

Activity description Institution / Organization
2025 - 2025 Reviewer of the “ Early Career Researcher Award”, ITQB-NOVA. Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2023/07 - 2023/07 Member of the evaluation committee for the award of a Master's Research Grant, within the scope of the project “DREBI - Exploring efflux inhibition to combat antimicrobial resistance and biofilms in staphylococci” - Ref. 2022.07931.PTDC Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Distinctions

Award

2024 Publications with Impact "Drug Repurposing for COVID-19: A Review and a Novel Strategy to Identify New Targets and Potential Drug Candidates"
Universidade Nova de Lisboa, Portugal

Other distinction

2018 MSCA-IF
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium
2012 Meeting Attendance Grant awarded by Federation of European Microbiology Societies (FEMS)
Federation Of European Microbiological Societies, United Kingdom
2011 Short-term fellowship awarded by the European Molecular Biology Organization (EMBO)
Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany
2011 Meeting Attendance Grant awarded by Federation of European Microbiology Societies (FEMS)
Federation Of European Microbiological Societies, United Kingdom
2006 Short -term training grant awarded by FCT
Fundação para a Ciência e a Tecnologia, Portugal