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Biotechnologist with a Ph.D. in Bio-systems Sustainability and over a decade of experience in microbial biotechnology, synthetic biology, and molecular microbiology. I have a strong track record across academia and industry, leading research on the genetic engineering of yeasts, filamentous fungi, and microalgae for applications in vaccine manufacturing, sustainable food innovation, and bio-based production systems. My international career spans Brazil, Japan, Germany, and the United Kingdom, including postdoctoral positions at TU Dresden and Imperial College London. In June 2026, I will begin a prestigious Marie Sklodowska-Curie Actions (MSCA) Postdoctoral Fellowship at IST Lisboa, further advancing my research in cutting-edge biotechnological innovation. I bring extensive experience in project and data management, interdisciplinary collaboration, student supervision, and competitive grant writing. With a strong publication record and experience in both startup and academic environments, I am committed to translating fundamental science into scalable, real-world solutions that address global sustainability and health challenges.
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Identification

Personal identification

Full name
Andre Ohara

Citation names

  • Ohara, Andre

Author identifiers

Ciência ID
521E-2799-C4B9
ORCID iD
0000-0002-9792-284X

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Engineering and Technology - Industrial Biotechnology - Fermentation
  • Engineering and Technology - Industrial Biotechnology - Bioproducts Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Japanese Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2026/04/27 - 2026/05/01
Concluded
 Introduction to metabolomics analysis - 40 h (Others)
European Bioinformatics Institute, United Kingdom
2026 - 2026
Concluded
 Curso Teórico On-line de Ciências de Animais de Laboratório (Others)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2025 - 2025
Concluded
 Opentrons OT-2 training - Automated high-throughput platform suite (ATLAS) (10 hours) (Others)
Imperial College London Department of Chemical Engineering, United Kingdom
2024 - 2024
Concluded
 R for Biochemist Biochemical Society UK (10 hours) (Others)
Biochemical Society, United Kingdom
2014 - 2018
Concluded
 Ph.D. in Bio-systems Sustainability - Applied Molecular Microbiology Laboratory (Doctor of Philosophy)
Hokkaido Daigaku Nogakubu Daigakuin Nogaku Kenkyuin Nogakuin, Japan
"Analysis of the DNA damage signal transducer ortholog Mop53BP1 in Pyricularia oryzae." (THESIS/DISSERTATION)
2014 - 2014
Concluded
 Bioinformatics: Introduction and Methods Online Course 36h (Others)
Peking University School of Life Sciences, China
2012 - 2014
Concluded
 M.Sc. in Food Science - Food Biochemistry Laboratory (Master)
Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil
"Isolation and characterization of yeasts from unexplored Brazilian Forests, verification of their potential to produce enzymes and vitamin B complex." (THESIS/DISSERTATION)
2008 - 2011
Concluded
 B.Sc. in Biotechnology (Bachelor)
Universidade Federal de São Carlos, Brazil
Affiliation

Science

Category
Host institution		 Employer
2026 - 2028 Contracted Researcher (Research) Centro de Recursos Naturais e Ambiente, Portugal
2022/08 - 2026/03 Postdoc (Research) Imperial College London Department of Chemical Engineering, United Kingdom
2022/05 - 2022/07 Researcher (Research) Phycobloom , United Kingdom
2021/01 - 2021/12 Researcher (Research) BioinFood, Brazil
2018 - 2020 Postdoc (Research) Technische Universität Dresden B CUBE, Germany

Teaching in Higher Education

Category
Host institution		 Employer
2022 - 2026 Assistant (University Teacher) Imperial College London Department of Chemical Engineering, United Kingdom
2021/05/01 - 2022/09/01 Invited Assistant (University Teacher) Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil
Projects

Grant

Designation Funders
2014 - 2018 Investigating the DNA damage signal transducer ortholog Mop53BP1 in Pyricularia oryzae
0004
PhD Student Fellow
Hokkaido Daigaku Nogakubu Daigakuin Nogaku Kenkyuin Nogakuin, Japan
Concluded
2012 - 2014 Isolamento e seleção de leveduras silvestres de biomas do estado de são paulo com potencial para produção de lipase e vitaminas do complexo b
12/02538-5
Master Student Fellow
Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil
Concluded

Contract

Designation Funders
2026/06/01 - 2028/05/31 ENDOMICS | Elucidating the Evolution of Endothermy through an Endolymphomics Approach
101244190
Principal investigator
Centro de Recursos Naturais e Ambiente, Portugal
 Horizon 2020
Ongoing
2022 - 2026 Re-engineering next-generation yeast platforms
0003
Researcher
Imperial College London - North West London Hospitals Campus, United Kingdom
 UK Research and Innovation
Ongoing
2025/01 - 2025/12 Modulating the postbiotic effects of Saccharomyces boulardii through integrated OMICS approaches and synthetic biology (PostBioeng)
0001
Principal investigator
Imperial College London, United Kingdom
 Imperial College London
Concluded
2023 - 2024 Exosome Engineering for Precise Targeting and Repair of Ischemic Blood Vessels
0002
Co-Principal Investigator (Co-PI)
Imperial College London, United Kingdom
 Imperial College London
Concluded
Outputs

Publications

Book chapter
  1. Ohara, Andre; MACEDO, G. A.. "Produção Biotecnológica de Vitaminas.". In Microbiologia Industrial. Amsterdã, Netherlands: Elsevier, 2017.
    Published
  2. Ohara, Andre; DE CASTRO, R. J. S.; OKURO, P. K.; UTSUNOMIA, C.; ANGELOTTI, J. A. F. ; LIMA, F. A.; HARUMI SATO, HÉLIA. "Soy Protein-Based Blends, Composites and Nanocomposites". In Applications of Soy Protein-Based Blends, Composites, and Nanocomposites., 67-102. United States: John Wiley & Sons, 2017.
    Published
Conference abstract
  1. Ohara, Andre; Zhang P.; Xinqi C.; Donini R.; Haslam S. M. ; Polizzi K M. "The impact of methanol concentration on recombinant protein glycosylation in Pichia pastoris SuperMan5". Paper presented in 12th Conference on Recombinant Protein Production, Ulm, 2025.
    Published
  2. Ohara, Andre; Polizzi K. "Integrated automation and secretion pathway optimization for glycoprotein vaccine production in Pichia pastoris". Paper presented in Imperial Network for Vaccine Research (INVaR) Annual meeting, Londres, 2025.
    Published
  3. Ohara, Andre; Polizzi K. "A rapid and versatile ELISA-based method for screening of heterologous protein expression in Pichia pastoris.". Paper presented in Chemical Engineering Postdoc Symposium – Imperial College London, 2023.
  4. Ohara, Andre; ABE, A; SONE, T. "Analysis of the DNA damage signal transducer ortholog Mop53BP1 in Pyricularia oryzae". Paper presented in Annual Meeting of the Phytopathological Society of Japan, Kobe, 2018.
  5. Ohara, Andre; ABE, A.; SONE, T.. "The DNA damage signal transducer ortholog Mop53BP1 is expressed in germinating conidia of Pyricularia oryzae". Paper presented in Annual Meeting of the Phytopathological Society of Japan, Morioka, 2017.
  6. Ohara, Andre; TASHIKA, Y.; ABE, A.; ASANO, K.; SONE, T.. "Study on Mop53BP1, gene for DNA damage signal transducer in Magnaporthe oryzae". Paper presented in Annual Meeting of the Phytopathological Society of Japan, Okayama, 2016.
    Published
  7. Ohara, Andre; CASTRO, R J S; GOIA, N T; GONÇALVES DIAS, F F; PAVAN BAGAGLI, M; SATO, H H. "Application of mixture design in solid state fermentation using agro-industrial wastes for enzymes production.". Paper presented in BITs 6th Annual World Gene Convention, Qingdao, 2015.
    Published
Conference poster
  1. Ohara, Andre; POLIZZI, K.. "Enhancing Recombinant Protein Vaccine Production: Insights from P. Pastoris Secretion and Immune Response Screening". Paper presented in SEED - 2024 Synthetic Biology: Engineering, Evolution & Design, 2024.
  2. Ohara, Andre; POLIZZI, K.. "Improving Pichia pastoris for Efficient Vaccine Production: Two-Step ELISA Screening for Productivity and Carbohydrate Interactions". Paper presented in Pichia 2024, 2024.
  3. Ohara, Andre; SKEFFINGTON, A; MILENTYEV, A; HEINTZE, C ; GORLICH, S; POULSEN, N; KROGER, N. "Characteristics of Proteins in soluble Biosilicomes from three Diatom Species". Paper presented in he molecular life of diatoms, 2019.
  4. Ohara, Andre; SILVA, E. B.; FERNANDES, C. M.; MACEDO, G.A.. "Bioprospection of riboflavin producing yeasts by UV-VIS spectroscopy and fluorescence". Paper presented in Simpósio Latino Americano de Ciência de Alimentos, 2013.
  5. Ohara, Andre; SILVA, E. B.; FERNANDES, C. M.; MACEDO, G.A.. "Isolamento e seleção de fungos e leveduras silvestres com potencial para produção de lipase". Paper presented in XIX Simpósio Nacional de Bioprocessos (SINAFERM) e o X Simpósio de Hidrólise Enzimática de Biomassas (SHEB), 2013.
  6. Ohara, Andre; SILVA, E. B.; FERNANDES, C. M.; MACEDO, G. A... "solamento e seleção de leveduras silvestres com potencial para produção de vitaminas do complexo B". Paper presented in XIX Simpósio Nacional de Bioprocessos (SINAFERM) e o X Simpósio de Hidrólise Enzimática de Biomassas (SHEB), 2013.
Journal article
  1. Liu, Yu; Pieters, Saskia; Bineva-Todd, Ganka; Sagiroglugil, Mert; Burnap, Sean A.; Hoddle, Freya; Cioce, Anna; et al. "Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for <i>N</i> -Acetylglucosaminyltransferase I". Journal of the American Chemical Society 148 27 (2026): 28190-28201. https://doi.org/10.1021/jacs.6c01114.
    10.1021/jacs.6c01114
  2. Andre Ohara; Zhang Pengyue; Xinqi Cao; Roberto Donini; Stuart M. Haslam; Karen M. Polizzi. "The Impact of Methanol Concentration on Recombinant Protein Glycosylation in <i>Pichia pastoris</i> <scp>SuperMan5</scp>". Microbial Biotechnology (2025): http://dx.doi.org/10.1111/1751-7915.70272.
    10.1111/1751-7915.70272
  3. Yu Liu; Ganka Bineva-Todd; Richard W. Meek; Laura Mazo; Beatriz Piniello; Olga Moroz; Sean A. Burnap; et al. "A Bioorthogonal Precision Tool for Human <i>N</i>-Acetylglucosaminyltransferase V". Journal of the American Chemical Society (2024): http://dx.doi.org/10.1021/jacs.4c05955.
    10.1021/jacs.4c05955
  4. Gustavo P. Lorca Mandujano; Henrique C. Alves; Cleiton D. Prado; Jeferson G.O. Martins; Hosana R. Novaes; João Pedro Maia de Oliveira da Silva; Gleidson Silva Teixeira; et al. "Identification and selection of a new Saccharomyces cerevisiae strain isolated from Brazilian ethanol fermentation process for application in beer production". Food Microbiology 103 (2022): 103958-103958. http://dx.doi.org/10.1016/j.fm.2021.103958.
    10.1016/j.fm.2021.103958
  5. "Using Correlative Superresolution Fluorescence and Electron Microscopy to Unravel Diatom Morphogenesis". Biophysical Journal (2020): http://dx.doi.org/10.1016/j.bpj.2019.11.932.
    10.1016/j.bpj.2019.11.932
  6. Ohara, A.; Cason, V.G.; Nishide, T.G.; Miranda de Matos, F.; de Castro, R.J.S.. "Improving the antioxidant and antidiabetic properties of common bean proteins by enzymatic hydrolysis using a blend of proteases". Biocatalysis and Biotransformation (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087635122&partnerID=MN8TOARS.
    10.1080/10242422.2020.1789114
  7. "A multicomponent system based on a blend of agroindustrial wastes for the simultaneous production of industrially applicable enzymes by solid-state fermentation". Food Science and Technology (2018): http://dx.doi.org/10.1590/1678-457x.17017.
    10.1590/1678-457x.17017
  8. "Nutritional, functional and biological properties of insect proteins: Processes for obtaining, consumption and future challenges". Trends in Food Science & Technology (2018): http://dx.doi.org/10.1016/j.tifs.2018.04.006.
    10.1016/j.tifs.2018.04.006
  9. "The DNA damage signal transducer ortholog Mop53BP1 is required for proper appressorium differentiation and pathogenicity in Pyricularia oryzae". Journal of General Plant Pathology (2018): http://dx.doi.org/10.1007/s10327-018-0780-9.
    10.1007/s10327-018-0780-9
  10. "Whey protein as a key component in food systems: Physicochemical properties, production technologies and applications". Food Structure (2017): http://dx.doi.org/10.1016/j.foostr.2017.05.004.
    10.1016/j.foostr.2017.05.004
  11. "Fungi from Brazilian Savannah and Atlantic rainforest show high antibacterial and antifungal activity". Biocatalysis and Agricultural Biotechnology (2017): http://dx.doi.org/10.1016/j.bcab.2017.01.011.
    10.1016/j.bcab.2017.01.011
  12. "A versatile system based on substrate formulation using agroindustrial wastes for protease production by Aspergillus niger under solid state fermentation". Biocatalysis and Agricultural Biotechnology (2015): http://dx.doi.org/10.1016/j.bcab.2015.08.010.
    10.1016/j.bcab.2015.08.010
  13. "Simplex centroid mixture design to improve l -asparaginase production in solid-state fermentation using agroindustrial wastes". Biocatalysis and Agricultural Biotechnology (2015): http://dx.doi.org/10.1016/j.bcab.2015.09.011.
    10.1016/j.bcab.2015.09.011
  14. André Ohara; Ruann Janser Soares de Castro; Tânia Goia Nishide; Fernanda Furlan Gonçalves Dias; Marcela Pavan Bagagli; Hélia Harumi Sato. "Invertase production by Aspergillus niger under solid state fermentation: Focus on physical–chemical parameters, synergistic and antagonistic effects using agro-industrial wastes". Biocatalysis and Agricultural Biotechnology 4 4 (2015): 645-652. http://dx.doi.org/10.1016/j.bcab.2015.06.008.
    10.1016/j.bcab.2015.06.008
  15. "A new approach for proteases production by Aspergillus niger based on the kinetic and thermodynamic parameters of the enzymes obtained". Biocatalysis and Agricultural Biotechnology (2015): http://dx.doi.org/10.1016/j.bcab.2014.12.001.
    10.1016/j.bcab.2014.12.001
  16. "Screening of filamentous fungi from Brazilian rainforests for enzyme production". African Journal of Microbiology Research (2015): http://dx.doi.org/10.5897/ajmr2014.7234.
    10.5897/ajmr2014.7234
Thesis / Dissertation
  1. "Analysis of the DNA damage signal transducer ortholog Mop53BP1 in Pyricularia oryzae". PhD, Hokkaido Daigaku Nogakubu Daigakuin Nogaku Kenkyuin Nogakuin, 2018. https://eprints.lib.hokudai.ac.jp/repo/huscap/all/70184/.
  2. "Isolamento e seleção de leveduras silvestres de biomas do Estado de São Paulo com potencial para produção de lipase e vitaminas do complexo B". Master, Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, 2014. https://repositorio.unicamp.br/acervo/detalhe/928002.

Other

Other output
  1. Shedding light on biosilica morphogenesis by comparative analysis of the silica-associated proteomes from three diatom species. 2021. Alastair W. Skeffington; Marc Gentzel; Andre Ohara; Alexander Milentyev; Christoph Heintze; Lorenz Böttcher; Stefan Görlich; et al. https://doi.org/10.1101/2021.09.18.460806.
    10.1101/2021.09.18.460806
Activities

Supervision

Thesis Title
Role		 Degree Subject (Type)
Institution / Organization
2025 - 2025 Automated ELISA Platform for HighThroughput Screening of Recombinant SARSCoV-2 RBD Protein for Vaccine Production
Co-supervisor
 Chemical Engineering MSc (Master)
Imperial College London Department of Chemical Engineering, United Kingdom
2024 - 2024 Expression of the HPV 35 L1 Protein in Pichia Pastoris
Co-supervisor
 Chemical Engineering MSc (Master)
Imperial College London Department of Chemical Engineering, United Kingdom
2023 - 2023 The influence of Pichia pastoris Glycosylation in the Glycan Binding Specificity of Human 1076 P[6] Rotavirus VP8*
Co-supervisor
 Chemical Engineering MSc (Master)
Imperial College London Department of Chemical Engineering and Chemical Technology, United Kingdom
2023 - 2023 Response surface methodology based optimization of human Wa rotavirus VP8* from Pichia pastoris
Co-supervisor
 Chemical Engineering MSc (Master)
Imperial College London Department of Chemical Engineering, United Kingdom

Event organisation

Event name
Type of event (Role)		 Institution / Organization
2019 - 2019 Monitor: Dresden Science Night (2019 - 2019)
Exhibition (Co-organiser)
 Technische Universität Dresden B CUBE, Germany
2013 - 2013 Monitor do XI Ciência e Arte nas Férias, realizando atividades junto ao projeto de produção, aplicações e efeitos deteriorativos de enzimas importantes em alimentos. (2013 - 2013)
Workshop (Co-organiser)
 Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil
2012 - 2012 Monitor no Unicamp de Portas Abertas (UPA) (2012 - 2012)
Workshop (Co-organiser)
 Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil

Event participation

Activity description
Type of event		 Event name
Institution / Organization
2020 - 2020 Machine Learning e Engenharia de Enzimas
Round table
 Conexao FEA
Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil

Association member

Society Organization name Role
2026 - Current Órgão responsável pelo bem-estar dos animais (ORBEA) - Centro de Ciências e Tecnologias Nucleares - Instituto Superior Técnico - Universidade de Lisboa Membro do ORBEA-CTN.
2014 - Current Associação Brasileira dos Bolsistas do Governo Japonês (ABMON/ABMONBOKU – Monbukagakusho Alumni Association, Brazil) Membro da ABMON

Consulting

Activity description Institution / Organization
2024 - 2024 Consulting service: Production of enzymes for the hydrolysis of lignocellulosic wastes to produce high-value acids for the cosmetic industry Imperial College London Department of Chemical Engineering, United Kingdom
2013 - 2013 Consulting service: Optimizaition of hydrolysis conditions for invertase enzyme recovery from yeast biomass waste. Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021 - 2022 Applied Food Biotechnology Applied Food Biotechnology (Master) Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil

Evaluation committee

Activity description
Role		 Institution / Organization Funding entity
2024 - 2024 Banca avaliadora de trabalho de conclusão de Mestrado. Aluna: Beatriz Veltre Costa. Dissertação: Biotransformação de farinhas da região amazônica por processos fermentativos para produção de ingredientes com melhores propriedades bioativas e tecnofuncionais.
Evaluator
 Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos, Brazil

Journal scientific committee

Journal title (ISSN) Publisher
2025 - 2025 Food and Humanity Elsevier
2025 - 2025 Scientific Reports Springer Nature
2025 - 2025 Biotechnology for Biofuels and Bioproducts Springer Nature
2025 - 2025 World Journal of Microbiology and Biotechnology Springer Nature
2025 - 2025 ACS Food Science & Technology ACS Paragon Plus
2024 - 2024 Preparative Biochemistry & Biotechnology Taylor and Francis
2024 - 2024 Brazilian Journal of Food Technology Instituto de Tecnologia de Alimentos - ITAL
2023 - 2023 Journal, Waste and Biomass Valorization Springer Nature
2022 - 2022 Journal of Oleo Science Japan Oil Chemists' Society
Distinctions

Award

2017 Excellent oral presentation award received during the Annual Meeting of the Phytopathological Society of Japan in Morioka
Phytopathological Society of Japan , Japan