Isaura Ferreira Tavares (4E19-004B-EB5C)

Curriculum Vitae

Isaura Ferreira Tavares

Identification

Personal identification

Full name: Isaura Ferreira Tavares

Citation names

Tavares, Isaura

Author identifiers

Ciência ID: 4E19-004B-EB5C
ORCID iD: 0000-0001-5696-1239

Education

	Degree	Classification
2007/12 Concluded	Neurociências (Título de Agregado) Universidade do Porto Faculdade de Medicina, Portugal
1993/07 - 1998/07/18 Concluded	Neurociências (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
1998 Concluded	Biologia (Ramo Científico) (Licenciatura) Universidade do Porto, Portugal "Conexões Entre o Corno Dorsal Superficial e a Formação Recticular Ventrolateral do Bolbo Raquidiano" (THESIS/DISSERTATION)

Affiliation

Teaching in Higher Education

	Category Host institution	Employer
2021/11 - Current	Full Professor (University Teacher)	Universidade do Porto, Portugal
	Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2021	Associate Professor (University Teacher)	Universidade do Porto, Portugal

2016 - 2019	Associate Professor (University Teacher)	Universidade do Porto, Portugal

2016 - 2019	Associate Professor (University Teacher)	Universidade do Porto, Portugal

2016 - 2019	Associate Professor (University Teacher)	Universidade do Porto, Portugal

2013 - 2016	Associate Professor (University Teacher)	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2016	Associate Professor (University Teacher)	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2016	Associate Professor (University Teacher)	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2016	Associate Professor (University Teacher)	Universidade do Porto Faculdade de Medicina, Portugal

Positions / Appointments

	Category Host institution	Employer
2018/06 - 2022/06	Conselho pedagógico	Universidade do Porto, Portugal

2018 - 2019	Conselho pedagógico	Universidade do Porto, Portugal

2018 - 2019	Conselho pedagógico	Universidade do Porto, Portugal

2018 - 2019	Conselho pedagógico	Universidade do Porto, Portugal

2016 - 2019	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto, Portugal

2016 - 2019	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto, Portugal

2016 - 2019	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto, Portugal

2016 - 2019	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto, Portugal

2013 - 2016	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2016	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2016	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2016	Conselho científico/técnico-científico ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2014	Conselho de gestão ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2014	Conselho de gestão ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2014	Conselho de gestão ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

2013 - 2014	Conselho de gestão ou orgão correspondente	Universidade do Porto Faculdade de Medicina, Portugal

Projects

Grant

	Designation	Funders
2015/05 - 2018/07	Appetite neurobiology and modulation of nociceptive trigeminovascular inputs-Studies to understand migraine pathophysiology SFRH/BD/77127/2011 Supervisor Universidade do Porto Faculdade de Medicina, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded
2011/03 - 2014/03	Pain facilitation in chronic pain: descending spinal modulation by the dorsal reticular nucleus SFRH/BD/71219/2010 Supervisor Universidade do Minho Escola de Medicina, Portugal	Associação para a Inovação e Desenvolvimento da FCT
2009/09 - 2011/09	O sistema somatossensitivo do rato com neuropatia diabética SFRH/BD/21555/2005 Supervisor Universidade do Porto Faculdade de Medicina Dentária, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded
2004/06 - 2008/03	Modificações do sistema endógeno de controlo da dor em processos dolorosos agudos e crónicos SFRH/BD/22995/2005 Supervisor Universidade do Porto Faculdade de Medicina, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded

Contract

	Designation	Funders
2023/01/15 - 2026/01/14	Circuitos dopaminérgicos de codificação de hábitos e dependência em modelos animais de dor crónica 2022.05193.PTDC 10.54499/2022.05193.PTDC Instituto de Astrofísica e Ciências do Espaço, Portugal Universidade do Porto Faculdade de Medicina, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/01/15 - 2026/01/14	Circuitos dopaminérgicos de codificação de hábitos e dependência em modelos animais de dor crónica 2022.05193.PTDC 10.54499/2022.05193.PTDC Instituto de Astrofísica e Ciências do Espaço, Portugal Universidade do Porto Faculdade de Medicina, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	Instituto de Investigação e Inovação em Saúde LA/P/0070/2020 10.54499/LA/P/0070/2020 Instituto de Astrofísica e Ciências do Espaço, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	Instituto de Investigação e Inovação em Saúde LA/P/0070/2020 10.54499/LA/P/0070/2020 Instituto de Astrofísica e Ciências do Espaço, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2019/01/01 - 2019/12/31	Instituto de Investigação e Inovação em Saúde UID/BIM/04293/2019 Instituto de Astrofísica e Ciências do Espaço, Portugal Universidade do Porto, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2019/01/01 - 2019/12/31	Instituto de Investigação e Inovação em Saúde UID/BIM/04293/2019 Instituto de Astrofísica e Ciências do Espaço, Portugal Universidade do Porto, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/06 - 2019/10	Neuropatia induzida por cistostáticos NORTE-01-0145-FEDER-000008 Post-doc Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded
2012/11 - 2016/10	Repair of Diabetic Damage by Stromal Cell Administration FPF7, Projeto nº 305736 Principal investigator Universidade do Porto Faculdade de Medicina, Portugal	European Union Concluded
2013/05/01 - 2015/12/31	Mecanismos moleculares da dor crónica: uma abordagem integrada com base em modelos animais geneticamente manipulados RECI/NEU-NMC/0138/2012 Researcher Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/05/01 - 2015/12/31	Mecanismos moleculares da dor crónica: uma abordagem integrada com base em modelos animais geneticamente manipulados RECI/NEU-NMC/0138/2012 Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/05/01 - 2015/12/31	Mecanismos moleculares da dor crónica: uma abordagem integrada com base em modelos animais geneticamente manipulados RECI/NEU-NMC/0138/2012 Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/05/01 - 2015/12/31	Mecanismos moleculares da dor crónica: uma abordagem integrada com base em modelos animais geneticamente manipulados RECI/NEU-NMC/0138/2012 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/05/01 - 2015/12/31	Mecanismos moleculares da dor crónica: uma abordagem integrada com base em modelos animais geneticamente manipulados RECI/NEU-NMC/0138/2012 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2014/04/07 - 2015/07/31	Terapia com células estaminais mesenquimatosas para prevenção dos efeitos da diabetes no sistema nervoso central EXPL/NEU-SCC/1928/2013 Researcher Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal National University of Ireland, Ireland	Fundação para a Ciência e a Tecnologia Concluded
2014/04/07 - 2015/07/31	Terapia com células estaminais mesenquimatosas para prevenção dos efeitos da diabetes no sistema nervoso central EXPL/NEU-SCC/1928/2013 Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal National University of Ireland, Ireland	Fundação para a Ciência e a Tecnologia Concluded
2014/04/07 - 2015/07/31	Terapia com células estaminais mesenquimatosas para prevenção dos efeitos da diabetes no sistema nervoso central EXPL/NEU-SCC/1928/2013 Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal National University of Ireland, Ireland	Fundação para a Ciência e a Tecnologia Concluded
2014/04/07 - 2015/07/31	Terapia com células estaminais mesenquimatosas para prevenção dos efeitos da diabetes no sistema nervoso central EXPL/NEU-SCC/1928/2013 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal National University of Ireland, Ireland	Fundação para a Ciência e a Tecnologia Concluded
2014/04/07 - 2015/07/31	Terapia com células estaminais mesenquimatosas para prevenção dos efeitos da diabetes no sistema nervoso central EXPL/NEU-SCC/1928/2013 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal National University of Ireland, Ireland	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2013/12/31	O encéfalo na dor crónica: estudo dos mecanismos de facilitação da dor mediados por receptores opióides do tipo mu PTDC/SAU-NSC/110954/2009 Principal investigator Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2013/12/31	O encéfalo na dor crónica: estudo dos mecanismos de facilitação da dor mediados por receptores opióides do tipo mu PTDC/SAU-NSC/110954/2009 Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2013/12/31	O encéfalo na dor crónica: estudo dos mecanismos de facilitação da dor mediados por receptores opióides do tipo mu PTDC/SAU-NSC/110954/2009 Universidade do Porto Faculdade de Medicina, Portugal Instituto de Biologia Molecular e Celular, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2013/12/31	O encéfalo na dor crónica: estudo dos mecanismos de facilitação da dor mediados por receptores opióides do tipo mu PTDC/SAU-NSC/110954/2009 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2013/12/31	O encéfalo na dor crónica: estudo dos mecanismos de facilitação da dor mediados por receptores opióides do tipo mu PTDC/SAU-NSC/110954/2009 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04/01 - 2013/09/30	Hipertensão e neuropatia dolorosa na diabetes. Papel da angiotensina II e do stresse oxidativo no sistema nervoso central. PTDC/SAU-NEU/101090/2008 Researcher Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04/01 - 2013/09/30	Hipertensão e neuropatia dolorosa na diabetes. Papel da angiotensina II e do stresse oxidativo no sistema nervoso central. PTDC/SAU-NEU/101090/2008 Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04/01 - 2013/09/30	Hipertensão e neuropatia dolorosa na diabetes. Papel da angiotensina II e do stresse oxidativo no sistema nervoso central. PTDC/SAU-NEU/101090/2008 Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04/01 - 2013/09/30	Hipertensão e neuropatia dolorosa na diabetes. Papel da angiotensina II e do stresse oxidativo no sistema nervoso central. PTDC/SAU-NEU/101090/2008 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04/01 - 2013/09/30	Hipertensão e neuropatia dolorosa na diabetes. Papel da angiotensina II e do stresse oxidativo no sistema nervoso central. PTDC/SAU-NEU/101090/2008 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2012/12/31	Projecto Estratégico - LA 2 - 2011-2012 PEst-C/SAU/LA0002/2011 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2012/12/31	Projecto Estratégico - LA 2 - 2011-2012 PEst-C/SAU/LA0002/2011 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/09/01 - 2011/01/31	Levando analgésicos derivados da Quiotorfina até ao encéfalo PTDC/SAU-FCF/69493/2006 Researcher Universidade de Lisboa Centro de Química e Bioquímica, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade do Porto Faculdade de Medicina, Portugal Universitat de Girona, Spain	Fundação para a Ciência e a Tecnologia Concluded
2007/09/01 - 2011/01/31	Levando analgésicos derivados da Quiotorfina até ao encéfalo PTDC/SAU-FCF/69493/2006 Universidade de Lisboa Centro de Química e Bioquímica, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade do Porto Faculdade de Medicina, Portugal Universitat de Girona, Spain	Fundação para a Ciência e a Tecnologia Concluded
2007/09/01 - 2011/01/31	Levando analgésicos derivados da Quiotorfina até ao encéfalo PTDC/SAU-FCF/69493/2006 Universidade de Lisboa Centro de Química e Bioquímica, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade do Porto Faculdade de Medicina, Portugal Universitat de Girona, Spain	Fundação para a Ciência e a Tecnologia Concluded
2007/09/01 - 2011/01/31	Levando analgésicos derivados da Quiotorfina até ao encéfalo PTDC/SAU-FCF/69493/2006 Universidade de Lisboa Centro de Química e Bioquímica, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade do Porto Faculdade de Medicina, Portugal Universitat de Girona, Spain Universidade de Lisboa Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/09/01 - 2011/01/31	Levando analgésicos derivados da Quiotorfina até ao encéfalo PTDC/SAU-FCF/69493/2006 Universidade de Lisboa Centro de Química e Bioquímica, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade do Porto Faculdade de Medicina, Portugal Universitat de Girona, Spain Universidade de Lisboa Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/10/01 - 2010/09/30	A diabetes e o sistema somatossensitivo: influência de disfunções na insulina e peptídeos relacionados na neuropatia diabética PTDC/SAU-OSM/64643/2006 Principal investigator Universidade do Porto Faculdade de Medicina, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/10/01 - 2010/09/30	A diabetes e o sistema somatossensitivo: influência de disfunções na insulina e peptídeos relacionados na neuropatia diabética PTDC/SAU-OSM/64643/2006 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/10/01 - 2010/09/30	A diabetes e o sistema somatossensitivo: influência de disfunções na insulina e peptídeos relacionados na neuropatia diabética PTDC/SAU-OSM/64643/2006 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/10/01 - 2010/09/30	A diabetes e o sistema somatossensitivo: influência de disfunções na insulina e peptídeos relacionados na neuropatia diabética PTDC/SAU-OSM/64643/2006 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/10/01 - 2010/09/30	A diabetes e o sistema somatossensitivo: influência de disfunções na insulina e peptídeos relacionados na neuropatia diabética PTDC/SAU-OSM/64643/2006 Universidade do Porto Faculdade de Medicina, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2003/08 - 2007/04	Hypertension-associated hypoalgesia: mechanisms and importance of the renin-angiotensin system in hypertension caused by adenosine receptor blockade POCTI/NSE/45409/2002 Universidade do Porto Faculdade de Medicina, Portugal	European Regional Development Fund Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book	Martins, I.; Tavares, I.. Gene therapy for chronic pain: How to manipulate and unravel pain control circuits from the brain?. 2015. 10.1007/978-1-4939-2306-9_13 Carvalho, Liliana S.; Patinha, Daniela; Peixoto, Carla; Maio, Inês; Cardoso, Orlando; Tavares, Isaura; Teixeira, António Albino; Pinho, Dora. Painful diabetic neuropathy under hypertensive conditions: a study in streptozotocin-diabetic rats. 2011.
Book chapter	Tavares, I; Martins, I. "Gene Therapy for Chronic Pain Management". 2013. 10.5772/55050 Tavares, I; Almeida, A; Lima, D. "Tract Tracing Methods at the Ultrastructural Level". 2002. 10.1007/978-0-387-22460-2_13
Book review	Martins-Oliveira, Margarida; Tavares, Isaura; Goadsby, Peter J.. "Was it something I ate? Understanding the bidirectional interaction of migraine and appetite neural circuits". http://hdl.handle.net/10362/126478. https://doi.org/10.1016/j.brainres.2021.147629 Martins-Oliveira, Margarida; Tavares, Isaura; Goadsby, Peter J.. "Was it something I ate? Understanding the bidirectional interaction of migraine and appetite neural circuits". http://hdl.handle.net/10362/126478. https://doi.org/10.1016/j.brainres.2021.147629
Conference abstract	Pereira, J; Oliveira, S; Tavares, I; Morgado, C. "Neuroinflammation and neurodegeneration in the prefrontal cortex during diabetic neuropathic pain". 2015. Köfalvi (Kofalvi, Käfalvi), Attila ; Morgado, Carla; Pedro, Joana Reis; Lemos, Cristina; Baptista, FI; Gaspar, Joana M.; Ambrósio, António F.; et al. "Streptozotocin-induced type-1 diabetes triggers deregulation of cerebral glucose metabolism identical to genetic deletion of the CB1 cannabinoid receptor". Paper presented in 8th FENS Forum of Neurocience, Barcelona, 2012. Silva, MA; Tavares, I; Morgado, C. "Serotonin pain facilitation through 5-HT3 receptor in diabetic neuropathic pain". 2012. Carvalho, Liliana S.; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Does genetic background affect the development of streptozotocin-induced diabetic neuropathy in rat?". 2012. Pinho, Dora; Albino-Teixeira, António; Carvalho, Liliana; Morais, Marina; Sousa, Raquel M.; Tavares, Isaura. "NADPH oxidase as a therapeutic target against neuropathic pain: evaluation of spinal redox dysfunction at early stages of the disease". 2012. Sousa, Raquel; Carvalho, Liliana; Morais, Marina; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Evaluation of redox dysfunction in the spinal cord of rats at early stages of peripheral neuropathic pain". 2012. Carvalho, Liliana S.; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Does strain influence pain perception profiles in streptozotocin-induced diabetic neuropathy rat model?". 2012. Pinho, Dora; Morais, Marina; Carvalho, Liliana; Sousa, Raquel M.; Marques-Lopes. José; Tavares, Isaura; Albino-Teixeira, António. "NADPH oxidase as a therapeutic target against neuropathic pain: a study in the angiotensin II-hypertensive Rat". 2012. Pinho, Dora; Dora Pinho; Liliana S. Carvalho; Daniela Patinha; Raquel M. Sousa; António Albino-Teixeira; Isaura Tavares; et al. "Hypertension and genetic background affect pain submodalities in streptozotocin-induced diabetic neuropathy". 2012. Ribeiro, MMB; Pinto, AT; Domingues, M; Heras, M; Bardaji, ER; Tavares, I; Castanho, MA. "Development of novel analgesic Kyotorphin-derived peptides: linking peptide-membrane interaction, Blood- Brain barrier crossing and in vivo efficacy". 2011. Morgado, C; Pereira Terra, P; Neto, F; Mixcoatl Zecuatl, T; Calcutt, NA; Tavares, I. "Impaired release of serotonin at the spinal cord of STZ-diabetic rats". 2011. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Pain and blood pressure modulation upon knockdown of NMDA receptor in the nucleus tractus solitarii". 2011. Carvalho, Liliana S.; Pinho, Dora; Patinha, Daniela; Lopes, José, Marques; Tavares, Isaura; Teixeira, António Albino. "Effects of hypertension on the different pain submodalities in painful diabetic neuropathy". 2011. Pinho, Dora; Carvalho, Liliana S.; Lopes, José Marques; Patinha, Daniela; Tavares, Isaura; Teixeira, António Albino. "The influence of hypertension in the development of painful diabetic neuropathy in rat". 2011. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Is NADPH oxidase a good target in the treatment of peripheral neuropathic pain in the hypertensive rat?". 2011. Carvalho, Liliana S.; Pinho, Dora; Patinha, Daniela; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Development of streptozotocin-induced painful diabetic neuropathy in hypertensive rats". 2011. Pinho, Dora; Carvalho, Liliana; Patinha, Daniela; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Interactions between cardiovascular and pain regulatory systems in streptozotocin-induced painful diabetic neuropathy". 2011. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Angiotensin II and NADPH oxidase in the pathophysiology of peripheral neuropathic pain". 2011. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Role of NMDA receptors in the interaction between nociception and cardiovascular control at the nucleus tractus solitarii: a gene-therapy study". 2011. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "A role for NADPH oxidase in the pathophysiology of peripheral neuropathic pain". 2011. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Hypoalgesia and increased blood pressure induced by decreased expression of NMDA receptors in the nucleus tractus solitarii". 2011. Morgado, CSC; Pereira Terra, P; Martins Oliveira, M; Neto, F; Tavares, I. "Oxidative stress damage at pain control serotoninergic and noradrenergic brainstem centres during diabetic neuropathy". 2010. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Wilson, Steven; Teixeira, António Albino; Tavares, Isaura. "Control of pain and blood pressure by the nucleus of the solitarii tract". 2010. Pinho, Dora; Patinha, Daniela; Couto, Marta; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Chronic pain under hypertensive conditions: is there a role for ROS?". 2010. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Wilson, Steven P; Teixeira, António Albino; Tavares, Isaura. "Nociception and cardiovascular control: a study on the nucleus of the solitarii tract". 2010. Pinho, Dora; Patinha, Daniela; Marques-Lopes, José; Couto, Marta R.; Tavares, Isaura; Albino-Teixeira, António. "Impact of hypertension on painful diabetic neuropathy in streptozotocin-diabetic rats". 2010. Pinho, D; Couto, M; Patinha, D; Marques Lopes, J; Tavares, I; Albino Teixeira, A. "DOES HYPERTENSION-ASSOCIATED HYPOALGESIA OCCUR IN NEUROPATHIC PAIN MODELS?". 2009. Ribeiro, M; Heras, M; Bardajo, E; Pinto, M; Tavares, I; Castanho, M. "Rationally designing new analgesic peptides: from biophysical screening to in vivo proof-of-concept". 2009. Morgado, C; Tavares, I. "Diabetes induces hyperactivity in the spinal dorsal horn neurons: a time-course study in streptozotocin-induced diabetic rats". 2008. Tavares, I; Castro, AR; Lima, D. "Descending modulation of nociceptive activation of spinal cord neurons expressing NK1 or GABA(B) receptors during chronic pain". 2007. Marques Lopes, J; Morato, M; Pinho, D; Sousa, T; Oliveira, S; Tavares, I; Albino Teixeira, A. "Evaluation of acute pain perception and blood pressure after angiotensin II administration in the caudal ventrolateral medulla". 2007. Morato, M; Pinho, D; Sousa, T; Marques Lopes, J; Tavares, I; Albino Teixeira, A. "The spinal GABAergic system and the VLMlat play a role in the inhibition of spinal dorsal horn neurones during hypertension". 2006. Pinho, D; Marques Lopes, J; Morato, M; Sousa, T; Tavares, I; Albino Teixeira, A. "The caudal ventrolateral medulla participates in the development and maintenance of adenosine receptor blockade-induced hypertension". 2006. Morato, M; Sousa, T; Tavares, I; Albino Teixeira, A. "The role of the caudal ventrolateral medulla in the hypoalgesia associated with hypertension". 2003. Lima, D; Tavares, I. "Spino-medullary circuitry in nociceptive cardiovascular integration". 2001. Lima, D; Tavares, I. "NK-1 receptor immunoreactivity is differentially expressed in lamina I spinal neurons projecting to the caudal ventrolateral medullary reticular formation". 2000. Tavares, I; Almeida, A; Albino Teixeira, A; Lima, D. "Nociceptive and cardiovascular integration at the caudal ventrolateral medulla". 1998. CASTROLOPES, JM; TAVARES, I; TOLLE, T; COIMBRA, A. "GABA INCREASE IN THE LUMBAR SPINAL-CORD OF RATS WITH CARRAGEENAN-INDUCED HINDPAW INFLAMMATION". 1992.
Conference paper	Carvalho, Liliana S.; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Does strain influence pain perception profiles in streptozotocin-induced diabetic neuropathy rat model?". 2012. Pinho, Dora; Morais, Marina; Carvalho, Liliana; Sousa, Raquel M.; Marques-Lopes. José; Tavares, Isaura; Albino-Teixeira, António. "NADPH oxidase as a therapeutic target against neuropathic pain: a study in the angiotensin II-hypertensive Rat". 2012. Sousa, Raquel; Carvalho, Liliana; Morais, Marina; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Evaluation of redox dysfunction in the spinal cord of rats at early stages of peripheral neuropathic pain". 2012. Pinho, Dora; Albino-Teixeira, António; Carvalho, Liliana; Morais, Marina; Sousa, Raquel M.; Tavares, Isaura. "NADPH oxidase as a therapeutic target against neuropathic pain: evaluation of spinal redox dysfunction at early stages of the disease". 2012. Pinho, Dora; Dora Pinho; Liliana S. Carvalho; Daniela Patinha; Raquel M. Sousa; António Albino-Teixeira; Isaura Tavares; et al. "Hypertension and genetic background affect pain submodalities in streptozotocin-induced diabetic neuropathy". 2012. Carvalho, Liliana; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Pain perception and NTS activation in hypertensive and normotensive rats with diabetic neuropathy". 2012. Carvalho, Liliana S.; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Does genetic background affect the development of streptozotocin-induced diabetic neuropathy in rat?". 2012. Dora Pinho; Marina Morais; Liliana S. Carvalho; Raquel M. Sousa; António Albino-Teixeira; Isaura Tavares. "The pursuit of a more effective therapeutic strategy for neuropathic pain: evaluation of spinal redox dysfunction at early stages of the disease". 2012. Pinho, Dora; Dora Pinho; Liliana S. Carvalho; Daniela Patinha; Raquel M. Sousa; António Albino-Teixeira; Isaura Tavares; et al. "Hypertension and genetic background affect pain submodalities in streptozotocin-induced diabetic neuropathy". 2012. Sousa, Raquel; Carvalho, Liliana; Morais, Marina; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Evaluation of redox dysfunction in the spinal cord of rats at early stages of peripheral neuropathic pain". 2012. Carvalho, Liliana S.; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Does strain influence pain perception profiles in streptozotocin-induced diabetic neuropathy rat model?". 2012. Carvalho, Liliana; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Pain perception and NTS activation in hypertensive and normotensive rats with diabetic neuropathy". 2012. Pinho, Dora; Morais, Marina; Carvalho, Liliana; Sousa, Raquel M.; Marques-Lopes. José; Tavares, Isaura; Albino-Teixeira, António. "NADPH oxidase as a therapeutic target against neuropathic pain: a study in the angiotensin II-hypertensive Rat". 2012. Pinho, Dora; Albino-Teixeira, António; Carvalho, Liliana; Morais, Marina; Sousa, Raquel M.; Tavares, Isaura. "NADPH oxidase as a therapeutic target against neuropathic pain: evaluation of spinal redox dysfunction at early stages of the disease". 2012. Dora Pinho; Marina Morais; Liliana S. Carvalho; Raquel M. Sousa; António Albino-Teixeira; Isaura Tavares. "The pursuit of a more effective therapeutic strategy for neuropathic pain: evaluation of spinal redox dysfunction at early stages of the disease". 2012. Carvalho, Liliana S.; Sousa, Raquel M.; Patinha, Daniela; Pinho, Dora; Tavares, Isaura; Albino-Teixeira, António. "Does genetic background affect the development of streptozotocin-induced diabetic neuropathy in rat?". 2012. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Hypoalgesia and increased blood pressure induced by decreased expression of NMDA receptors in the nucleus tractus solitarii". 2011. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Role of NMDA receptors in the interaction between nociception and cardiovascular control at the nucleus tractus solitarii: a gene-therapy study". 2011. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "A role for NADPH oxidase in the pathophysiology of peripheral neuropathic pain". 2011. Pinho, Dora; Carvalho, Liliana; Patinha, Daniela; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Interactions between cardiovascular and pain regulatory systems in streptozotocin-induced painful diabetic neuropathy". 2011. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Angiotensin II and NADPH oxidase in the pathophysiology of peripheral neuropathic pain". 2011. Carvalho, Liliana S.; Pinho, Dora; Patinha, Daniela; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Development of streptozotocin-induced painful diabetic neuropathy in hypertensive rats". 2011. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Is NADPH oxidase a good target in the treatment of peripheral neuropathic pain in the hypertensive rat?". 2011. Pinho, Dora; Carvalho, Liliana S.; Lopes, José Marques; Patinha, Daniela; Tavares, Isaura; Teixeira, António Albino. "The influence of hypertension in the development of painful diabetic neuropathy in rat". 2011. Carvalho, Liliana S.; Pinho, Dora; Patinha, Daniela; Lopes, José, Marques; Tavares, Isaura; Teixeira, António Albino. "Effects of hypertension on the different pain submodalities in painful diabetic neuropathy". 2011. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Pain and blood pressure modulation upon knockdown of NMDA receptor in the nucleus tractus solitarii". 2011. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura. "Hypoalgesia and increased blood pressure induced by decreased expression of NMDA receptors in the nucleus tractus solitarii". 2011. Carvalho, Liliana S.; Patinha, Daniela; Peixoto, Carla; Maio, Inês; Cardoso, Orlando; Tavares, Isaura; Teixeira, António Albino; Pinho, Dora. "Painful diabetic neuropathy under hypertensive conditions: a study in streptozotocin-diabetic rats". 2011. Pinho, Dora; Patinha, Daniela; Couto, Marta; Lopes, José Marques; Tavares, Isaura; Teixeira, António Albino. "Chronic pain under hypertensive conditions: is there a role for ROS?". 2010. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Wilson, Steven; Teixeira, António Albino; Tavares, Isaura. "Control of pain and blood pressure by the nucleus of the solitarii tract". 2010. Lopes, José Marques; Martins, Isabel; Pinho, Dora; Wilson, Steven P; Teixeira, António Albino; Tavares, Isaura. "Nociception and cardiovascular control: a study on the nucleus of the solitarii tract". 2010. Pinho, Dora; Patinha, Daniela; Marques-Lopes, José; Couto, Marta R.; Tavares, Isaura; Albino-Teixeira, António. "Impact of hypertension on painful diabetic neuropathy in streptozotocin-diabetic rats". 2010. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "The role of NAD(P)H oxidase in the pathophysiology of neuropathic pain under hypertensive conditions". 2010. Pinho, Dora; Carvalho, Liliana S.; Patinha, Daniela; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "The Relationship Between Cardiovascular and Pain Regulation in Painful Diabetic Neurophaty". 2010. Pinho, Dora; Morais, Marina; Patinha, Daniela; Couto, Marta R.; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "Effects of the NOX inhibitor apocynin in the development of peripheral neuropathic pain in Rat". 2010. Lima, D; Almeida, A; Tavares, I. "The endogenous pain control system: Facilitating and inhibitory pathways". 1998.
Conference poster	Martins-Oliveira, Margarida; Akerman, Simon; Holland, Philip R.; Tavares, Isaura; Goadsby, Peter J.. "Pleasure and pain: exploring neurobiological mechanisms of food craving before migraine pain. Journal: Cephalalgia.". Paper presented in 18th International Headache Congress (Vancouver, Canada), 2017. Marta Silva; Amorim, Diana Alexandra Silva; Carla Morgado; Almeida, Armando; Tavares, Isaura; Pinto-Ribeiro, Filipa. Corresponding author: Pinto-Ribeiro, Filipa. "Alterations of rostroventromedial medulla neuronal activity during painful diabetic neuropathy: effects in descending nociceptive modulation.". Paper presented in 14th World Congress on Pain, 2012. Marta Silva; Amorim, Diana Alexandra Silva; Carla Morgado; Almeida, Armando; Tavares, Isaura; Pinto-Ribeiro, Filipa. Corresponding author: Pinto-Ribeiro, Filipa. "Electrophysiological study of pronociceptive ON-cells and antinociceptive OFF-cells in the rostroventromedial medulla of STZ-diabetic rats.". Paper presented in 8th FENS Forum of Neuroscience, 2012. Castro, Ana Rita Fernandes Barros; Lima, Deolinda; Tavares, Isaura. "Descending modulation of secondary hyperalgesia in the monoarthritic rat: role of antinociceptive and pronociceptive medullary centres in the differential nociceptive activation of NK1 anf GABAB-expressing spinal cord neurons". Paper presented in Neurosciences 2006, 2006. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Lima, Deolinda; Tavares, Isaura. "Secondary hyperalgesia in the monoarthritic rat s reverted by destruction of spinal neurons expressing NK1 receptors and intrathecal baclofen administration". Paper presented in 5th Forum of European Neurosciences, 2006. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Lima, Deolinda; Tavares, Isaura. "Secondary hyperalgesia is accompanied by an imbalance of the expression of NK1 and GABAB receptors in nociceptive spinal neurons". Paper presented in Neurosciences 2004, 2004. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Spinal neurons bearing NK1- and GABAB-receptors are involved in secondary hyperalgesia in the monoarthritic rat". Paper presented in 4th Forum of European Neuroscience, 2004. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Chronic pain is accompanied by na imbalance of excitatory and inhibitory actions upon supraspinally projecting lamina I neurons". Paper presented in 3th World Congress World Institute of Pain, 2004. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Secondary hyperalgesia is associated with alterations in the expression of NK1- and GABAB-receptors in nociceptive spinal neurons". Paper presented in 1st Neuroscience Symposium of the International Institute for Neuroscience of Natal, 2004. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Spinal cord nociceptive neurons expressing NK1-receptors in normal and monoarthritic rats". Paper presented in 4th Congress of the European Federation of IASP, 2003. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Differential expression of NK1-receptors in nociceptive spinal neurons of normal and monoarthritic rats". Paper presented in 8ª Reunião da Sociedade Portuguesa de Neurociências, 2003. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Co-localization of NK1 and GABAB receptors in nociceptive neurons of the rat spinal cord". Paper presented in 23rd European Winter Conference on Brain Research, 2003. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Noxious mechanical activation of c-fos in spinal neurons immunoreactive for NK1- or GABAB-receptors in the rat". Paper presented in 10th World Congress on Pain, 2002. Castro, Ana Rita Fernandes Barros; Pinto, Marta; Tavares, Isaura; Lima, Deolinda. "Activation of spinal cord neurons immunoreactive for NK1 and GABAB receptors by noxious input: a c-fos study in the rat". Paper presented in XXXVII Reunião Anual da Sociedade Portuguesa de Microscopia Electrónica e Biologia Celular, 2002.
Journal article	Bento, JCFMD; Tavares, I; Pozza, DH. "Advancing pain education: a cross-sectional study in the Portuguese medical schools". BMC MEDICAL EDUCATION (2025): https://www.authenticus.pt/P-017-YV2. 10.1186/s12909-024-06582-w Lopes, Alexandra; Sampaio, Rute; Tavares, Isaura. "Pain, mindfulness, and placebo: a systematic review". Frontiers in Integrative Neuroscience 18 (2024): http://dx.doi.org/10.3389/fnint.2024.1432270. 10.3389/fnint.2024.1432270 Marta Louçano; Ana Coelho; Sílvia Sousa Chambel; Cristina Prudêncio; Célia Duarte Cruz; Isaura Tavares. "Noradrenergic Pathways Involved in Micturition in an Animal Model of Hydrocephalus—Implications for Urinary Dysfunction". Biomedicines (2024): https://doi.org/10.3390/biomedicines12010215. 10.3390/biomedicines12010215 Romualdo, JM; Borges, E; Tavares, I; Pozza, DH. "The interplay of fear of pain, emotional states, and pain perception in medical and nursing students: A cross-sectional study". PLOS ONE (2024): https://www.authenticus.pt/P-017-HAJ. 10.1371/journal.pone.0314094 Bruno Daniel Carneiro; Daniel Humberto Pozza; Isaura Tavares. "Perceptions of medical students towards the role of histology and embryology during curricular review". BMC Medical Education (2023): https://doi.org/10.1186/s12909-023-04019-4. 10.1186/s12909-023-04019-4 Dias, P; Tavares, I; Fonseca, S; Pozza, DH. "Outcomes of a QST Protocol in Healthy Subjects and Chronic Pain Patients: A Controlled Clinical Trial". BIOMEDICINES (2023): https://www.authenticus.pt/P-00Y-BRC. 10.3390/biomedicines11041023 Costa Pereira, JT; Oliveira, R; Guadilla, I; Guillen, MJ; Tavares, I; Lopez Larrubia, P. "Neuroimaging uncovers neuronal and metabolic changes in pain modulatory brain areas in a rat model of chemotherapy-induced neuropathy - MEMRI and ex vivo spectroscopy studies". BRAIN RESEARCH BULLETIN (2023): 10.1016/j.brainresbull.2022.10.018 Loucano, M; Oliveira, J; Martins, I; Vaz, R; Tavares, I. "Pain Modulation from the Locus Coeruleus in a Model of Hydrocephalus: Searching for Oxidative Stress-Induced Noradrenergic Neuroprotection". INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022): 10.3390/ijms23073970 Martins-Oliveira, Margarida; Akerman, Simon; Holland, Philip R.; Tavares, Isaura; Goadsby, Peter J.. "Pharmacological modulation of ventral tegmental area neurons elicits changes in trigeminovascular sensory processing and is accompanied by glycemic changes". (2022): http://hdl.handle.net/10362/145104. https://doi.org/10.1177/03331024221110111 Louçano, Marta; Oliveira, Joana; Martins, Isabel; Vaz, Rui; Tavares, Isaura. "Pain modulation from the Locus Coeruleus in a model of hydrocephalus: searching for oxidative stress-induced noradrenergic neuroprotection". (2022): http://hdl.handle.net/10400.22/20556. 10.3390/ijms23073970 Martins Oliveira, M; Akerman, S; Holland, PR; Tavares, I; Goadsby, PJ. "Pharmacological modulation of ventral tegmental area neurons elicits changes in trigeminovascular sensory processing and is accompanied by glycemic changes: Implications for migraine". CEPHALALGIA (2022): https://www.authenticus.pt/P-00X-C03. 10.1177/03331024221110111 Tavares, I; Costa-Pereira, JT; Martins, I. "Monoaminergic and Opioidergic Modulation of Brainstem Circuits: New Insights Into the Clinical Challenges of Pain Treatment?". Frontiers in Pain Research (2021): 10.3389/fpain.2021.696515 Martins-Oliveira, Margarida; Akerman, Simon; Holland, Philip R.; Tavares, Isaura; Goadsby, Peter J.. "Ventral tegmental area modulates trigeminovascular neurons: relevance to premonitory food craving in migraine.". (2020): Under revision José Tiago Costa-Pereira; Paula Serrão; Isabel Martins; Isaura Tavares. "Serotoninergic pain modulation from the rostral ventromedial medulla (RVM) in chemotherapy-induced neuropathy: The role of spinal 5-HT3 receptors". European Journal of Neuroscience (2020): https://doi.org/10.1111/ejn.14614. 10.1111/ejn.14614 Costa, AR; Sousa, M; Wilson, SP; Reguenga, C; Teixeira Pinto, A; Tavares, I; Martins, I. "Shift of mu-opioid Receptor Signaling in the Dorsal Reticular Nucleus Is Implicated in Morphine-induced Hyperalgesia in Male Rats". ANESTHESIOLOGY (2020): 10.1097/aln.0000000000003412 Costa Pereira, JT; Ribeiro, J; Martins, I; Tavares, I. "Role of Spinal Cord alpha(2)-Adrenoreceptors in Noradrenergic Inhibition of Nociceptive Transmission During Chemotherapy-Induced Peripheral Neuropathy". FRONTIERS IN NEUROSCIENCE (2020): 10.3389/fnins.2019.01413 Pedro, JR; Moura, LIF; Valerio Fernandes, A; Baptista, FI; Gaspar, JM; Pinheiro, BS; Lemos, C; et al. "Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes". BRAIN RESEARCH BULLETIN (2020): 10.1016/j.brainresbull.2020.05.004 Costa, AR; Carvalho, P; Flik, G; Wilson, SP; Reguenga, C; Martins, I; Tavares, I. "Neuropathic Pain Induced Alterations in the Opioidergic Modulation of a Descending Pain Facilitatory Area of the Brain". FRONTIERS IN CELLULAR NEUROSCIENCE (2019): 10.3389/fncel.2019.00287 Martins, D.; Silva, M.; Tavares, I.. "TRPV1 in pain control from the brain". Oncotarget 8 10 (2017): 16101-16102. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014647057&partnerID=MN8TOARS. 10.18632/oncotarget.13316 Martins, I.; Tavares, I.. "Reticular formation and pain: The past and the future". Frontiers in Neuroanatomy 11 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85029141878&partnerID=MN8TOARS. 10.3389/fnana.2017.00051 Martins-Oliveira, M.; Akerman, S.; Holland, P.R.; Hoffmann, J.R.; Tavares, I.; Goadsby, P.J.. "Neuroendocrine signaling modulates specific neural networks relevant to migraine". Neurobiology of Disease 101 (2017): 16-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013073536&partnerID=MN8TOARS. 10.1016/j.nbd.2017.01.005 Marta Silva; José Tiago Costa-Pereira; Daniel Martins; Isaura Tavares. "Pain modulation from the brain during diabetic neuropathy: Uncovering the role of the rostroventromedial medulla". Neurobiology of Disease 96 (2016): 346-356. http://dx.doi.org/10.1016/j.nbd.2016.10.002. 10.1016/j.nbd.2016.10.002 M. Silva; D. Martins; A. Charrua; F. Piscitelli; I. Tavares; C. Morgado; V. Di Marzo. "Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy". Neuropharmacology 107 (2016): 49-57. https://doi.org/10.1016%2Fj.neuropharm.2016.03.007. 10.1016/j.neuropharm.2016.03.007 Santos, SS; Santos, SM; Pinto, ART; Ramu, VG; Heras, M; Bardaji, E; Tavares, I; Castanho, MARB. "Amidated and Ibuprofen-Conjugated Kyotorphins Promote Neuronal Rescue and Memory Recovery in Cerebral Hypoperfusion Dementia Model". FRONTIERS IN AGING NEUROSCIENCE (2016): https://www.authenticus.pt/P-00K-0JH. 10.3389/fnagi.2016.00001 Lombo, C; Morgado, C; Tavares, I; Neves, D. "Effects of prolonged ingestion of epigallocatechin gallate on diabetes type 1-induced vascular modifications in the erectile tissue of rats". INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH (2016): 10.1038/ijir.2016.19 Perazzo, J; Lopes Ferreira, M; Santos, SS; Serrano, I; Pinto, A; Lima, C; Bardaji, E; et al. "Endothelium-Mediated Action of Analogues of the Endogenous Neuropeptide Kyotorphin (Tyrosil-Arginine): Mechanistic Insights from Permeation and Effects on Microcirculation". ACS CHEMICAL NEUROSCIENCE (2016): https://www.authenticus.pt/P-00K-SWT. 10.1021/acschemneuro.6b00099 Oliveira, MC; Gano, L; Santos, I; Correia, JDG; Serrano, ID; Santos, SS; Ribeiro, M; et al. "Improvement of the pharmacological properties of amidated kyotorphin by means of iodination". MEDCHEMCOMM (2016): 10.1039/c6md00028b Silva, M.; Martins, D.; Tavares, I.; Morgado, C.. "Retracted: Inhibition of spinal 5-HT3R reverted diabetes-induced mechanical hypersensitivity in a GABAAR-mediated neurotransmission-dependent manner [Neuroscience 313 (2016) 236]". Neuroscience 313 (2016): 236-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-84949920909&partnerID=MN8TOARS. 10.1016/j.neuroscience.2015.12.002 Oliveira, M.-M.; Akerman, S.; Tavares, I.; Goadsby, P.J.. "Neuropeptide y inhibits the trigeminovascular pathway through NPY Y1 receptor: Implications for migraine". Pain 157 8 (2016): 1666-1673. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979693125&partnerID=MN8TOARS. 10.1097/j.pain.0000000000000571 Santos, Sónia Sá; Santos, Sara M.; Pinto, Antónia R. T.; Ramu, Vasanthakumar G.; Heras, Montserrat; Bardaji, Eduard; Tavares, Isaura; Castanho, Miguel A. R. B.. "Amidated and ibuprofen-conjugated kyotorphins promote neuronal rescue and memory recovery in cerebral hypoperfusion dementia model". (2016): http://hdl.handle.net/10451/32813. 10.3389/fnagi.2016.00001 Perazzo, Juliana; Ferreira, Mónica Lopes; Santos, Sónia Sá; Serrano, Isa; Pinto, Antónia; Lima, Carla; Bardaji, Eduard; et al. "Endothelium-mediated action of analogues of the endogenous neuropeptide kyotorphin (tyrosil-arginine) : mechanistic insights from permeation and effects on microcirculation". (2016): http://hdl.handle.net/10451/32812. 10.1021/acschemneuro.6b00099 Pereira, J.; Oliveira, S.; Tavares, I.; Morgado, C.. "Retraction Note: Abstracts of 51st EASD Annual Meeting [Diabetologia, Doi 10.1007/s00125-015-3687-4]". Diabetologia 59 3 (2016): 655-655. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957429330&partnerID=MN8TOARS. 10.1007/s00125-015-3851-x Santos, Sónia Sá; Santos, Sara M.; Pinto, Antónia R. T.; Ramu, Vasanthakumar G.; Heras, Montserrat; Bardaji, Eduard; Tavares, Isaura; Castanho, Miguel A. R. B.. "Amidated and ibuprofen-conjugated kyotorphins promote neuronal rescue and memory recovery in cerebral hypoperfusion dementia model". (2016): http://hdl.handle.net/10451/32813. 10.3389/fnagi.2016.00001 Perazzo, Juliana; Ferreira, Mónica Lopes; Santos, Sónia Sá; Serrano, Isa; Pinto, Antónia; Lima, Carla; Bardaji, Eduard; et al. "Endothelium-mediated action of analogues of the endogenous neuropeptide kyotorphin (tyrosil-arginine) : mechanistic insights from permeation and effects on microcirculation". (2016): http://hdl.handle.net/10451/32812. 10.1021/acschemneuro.6b00099 "Nociceptive spinal cord neurons of laminae I–III exhibit oxidative stress damage during diabetic neuropathy which is prevented by early antioxidant treatment with epigallocatechin-gallate (EGCG)". Brain Research Bulletin (2015): 10.1016/j.brainresbull.2014.12.004 Serrano, ID; Ramu, VG; Pinto, ART; Freire, JM; Tavares, I; Heras, M; Bardaji, ER; Castanho, MARB. "Correlation Between Membrane Translocation and Analgesic Efficacy in Kyotorphin Derivatives". BIOPOLYMERS (2015): https://www.authenticus.pt/P-00G-J61. 10.1002/bip.22580 Martins, I; Carvalho, P; de Vries, MG; Teixeira Pinto, A; Wilson, SP; Westerink, BHC; Tavares, I. "GABA acting on GABA(B) receptors located in a medullary pain facilitatory area enhances nociceptive behaviors evoked by intraplantar formalin injection". PAIN (2015): https://www.authenticus.pt/P-00G-FJB. 10.1097/j.pain.0000000000000203 Silva, M; Martins, D; Tavares, I; Morgado, C. "INHIBITION OF SPINAL 5-HT3R REVERTED DIABETES-INDUCED MECHANICAL HYPERSENSITIVITY IN A GABA(A)R-MEDIATED NEUROTRANSMISSION-DEPENDENT MANNER". NEUROSCIENCE (2015): https://www.authenticus.pt/P-00G-KHV. 10.1016/j.neuroscience.2015.07.050 Martins, I.; Carvalho, P.; de Vries, M.G.; Teixeira-Pinto, A.; Wilson, S.P.; Westerink, B.H.; Tavares, I.. "Increased noradrenergic neurotransmission to a pain facilitatory area of the brain is implicated in facilitation of chronic pain". Anesthesiology 123 3 (2015): 642-653. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946912857&partnerID=MN8TOARS. 10.1097/ALN.0000000000000749 Serrano, Isa D.; Ramu, Vasanthakumar G.; Pinto, Antónia R. T.; Freire, João M.; Tavares, Isaura; Heras, Montserrat; Bardaji, Eduard R.; Castanho, Miguel A. R. B.. "Correlation between membrane translocation and analgesic efficacy in kyotorphin derivatives". (2015): http://hdl.handle.net/10451/23431. 10.1002/bip.22580 Serrano, Isa D.; Ramu, Vasanthakumar G.; Pinto, Antónia R. T.; Freire, João M.; Tavares, Isaura; Heras, Montserrat; Bardaji, Eduard R.; Castanho, Miguel A. R. B.. "Correlation between membrane translocation and analgesic efficacy in kyotorphin derivatives". (2015): http://hdl.handle.net/10451/23431. 10.1002/bip.22580 Vaz, R; Barros, F; Tavares, I; Bustorff, M; Ferreira, I; Pestana, M. "Ganciclovir-resistant cytomegalovirus infection in renal transplantation". Clinical Kidney Journal (2014): 10.1093/ckj/sfu005 Silva, M.; Amorim, D.; Almeida, A.; Tavares, I.; Pinto-Ribeiro, F.; Morgado, C.. "Pronociceptive changes in the activity of rostroventromedial medulla (RVM) pain modulatory cells in the streptozotocin-diabetic rat". Brain Research Bulletin 96 (2013): 39-44. 10.1016/j.brainresbull.2013.04.008 Ribeiro, Marta M. B.; Santos, Sonia Sa; Sousa, David S. C.; Oliveira, Margarida; Santos, Sara M.; Heras, Montserrat; Bardaji, Eduard; Tavares, Isaura; Castanho, Miguel A. R. B.. "Side-effects of analgesic kyotorphin derivatives: advantages over clinical opioid drugs". Amino Acids 45 1 (2013): 171-178. 10.1007/s00726-013-1484-2 Tavares, Isaura. "Human neural stem cell transplantation in spinal cord injury models: how far from clinical application?". Stem Cell Research & Therapy 4 (2013): 10.1186/scrt210 Martins, I.; de Vries, M. G.; Teixeira-Pinto, A.; Fadel, J.; Wilson, S. P.; Westerink, B. H. C.; Tavares, I.. "Noradrenaline increases pain facilitation from the brain during inflammatory pain". Neuropharmacology 71 (2013): 299-307. 10.1016/j.neuropharm.2013.04.007 Santos, Sara Matos; Garcia-Nimo, Laura; Santos, Sonia Sa; Tavares, Isaura; Cocho, Jose A.; Castanho, Miguel A. R. B.. "Neuropeptide kyotorphin (tyrosyl-arginine) has decreased levels in the cerebro-spinal fluid of Alzheimer's disease patients: potential diagnostic and pharmacologic alimplications". Frontiers in Aging Neuroscience 5 (2013): 10.3389/fnagi.2013.00068 Santos, Sara Matos; Garcia-Nimo, Laura; Sá Santos, Sónia; Tavares, Isaura; Cocho, José A.; Castanho, Miguel A. R. B.. "Neuropeptide kyotorphin (tyrosyl-arginine) has decreased levels in the cerebro-spinal fluid of Alzheimer’s disease patients: potential diagnostic and pharmacological implications". (2013): http://dx.doi.org/10.3389/fnagi.2013.00068. http://dx.doi.org/10.3389/fnagi.2013.00068 Ribeiro, Marta M. B.; Santos, Sónia Sá; Sousa, David S. C.; Oliveira, Margarida; Santos, Sara M.; Heras, Montserrat; Bardaji, Eduard; Tavares, Isaura; Castanho, Miguel A. R. B.. "Side-effects of analgesic kyotorphin derivatives : advantages over clinical opioid drugs". (2013): http://dx.doi.org/10.1007/s00726-013-1484-2. http://dx.doi.org/10.1007/s00726-013-1484-2 Santos, Sara Matos; Garcia-Nimo, Laura; Sá Santos, Sónia; Tavares, Isaura; Cocho, José A.; Castanho, Miguel A. R. B.. "Neuropeptide kyotorphin (tyrosyl-arginine) has decreased levels in the cerebro-spinal fluid of Alzheimer’s disease patients: potential diagnostic and pharmacological implications". (2013): http://hdl.handle.net/10451/10715. http://dx.doi.org/10.3389/fnagi.2013.00068 Ribeiro, Marta M. B.; Santos, Sónia Sá; Sousa, David S. C.; Oliveira, Margarida; Santos, Sara M.; Heras, Montserrat; Bardaji, Eduard; Tavares, Isaura; Castanho, Miguel A. R. B.. "Side-effects of analgesic kyotorphin derivatives : advantages over clinical opioid drugs". (2013): http://hdl.handle.net/10451/10689. http://dx.doi.org/10.1007/s00726-013-1484-2 Morgado, Carla; Silva, Liliana; Pereira-Terra, Patricia; Tavares, Isaura. "Changes in serotoninergic and noradrenergic descending pain pathways during painful diabetic neuropathy: The preventive action of IGF1 (vol 43, pg 275, 2011)". Neurobiology of Disease 45 2 (2012): 829-829. 10.1016/j.nbd.2011.10.001 Marques-Lopes, J.; Martins, I.; Pinho, D.; Morato, M.; Wilson, S. P.; Albino-Teixeira, A.; Tavares, I.. "Decrease in the Expression of N-Methyl-D-Aspartate Receptors in the Nucleus Tractus Solitarii Induces Antinociception and Increases Blood Pressure". Journal of Neuroscience Research 90 2 (2012): 356-366. 10.1002/jnr.22760 Morgado, Carla; Silva, Joao; Miranda, Andre; Pereira-Terra, Patricia; Raposo, Diogo; Tavares, Isaura. "EGCG prevents the loss of pontine noradrenergic neurons induced by diabetes: a role in diabetic neuropathic pain". Microscopy and Microanalysis 18 (2012): 5-6. 10.1017/S1431927612012688 Lombo, C.; Tomada, I.; Morgado, C.; Tavares, I.; Neves, D.. "Immunofluorescent Characterization of VEGF, VEGFR1 and VEGFR2 Expression in the Corpus Cavernosum of the Diabetic Rat after Prolonged Ingestion of Epigallocatechin Gallate". Microscopy and Microanalysis 18 (2012): 9-10. 10.1017/S1431927612012706 Pinho, Dora; Albino-Teixeira, Antonio; Tavares, Isaura; Morato, Manuela; Martins, Isabel; Marques-Lopes, José; Wilson, Steven P. "Decrease in the expression of NMDA receptors in the nucleus tractus solitarii induces antinociception and increases blood pressure". (2012): https://repositorio-aberto.up.pt/handle/10216/96030. Morgado, Carla; Silva, João; Miranda, André; Terra, Patrícia Daniela Pereira; Raposo, Diogo; Tavares, Isaura. "EGCG prevents the loss of pontine noradrenergic neurons induced by diabetes: a role in diabetic neuropathic pain". (2012): http://hdl.handle.net/1822/67426. 10.1017/S1431927612012688 Pinho, Dora; Albino-Teixeira, Antonio; Tavares, Isaura; Morato, Manuela; Martins, Isabel; Marques-Lopes, José; Wilson, Steven P. "Decrease in the expression of NMDA receptors in the nucleus tractus solitarii induces antinociception and increases blood pressure". (2012): https://repositorio-aberto.up.pt/handle/10216/96030. Morgado, Carla; Silva, João; Miranda, André; Terra, Patrícia Daniela Pereira; Raposo, Diogo; Tavares, Isaura. "EGCG prevents the loss of pontine noradrenergic neurons induced by diabetes: a role in diabetic neuropathic pain". (2012): http://hdl.handle.net/1822/67426. 10.1017/S1431927612012688 Pinho, Dora; Albino-Teixeira, Antonio; Tavares, Isaura; Morato, Manuela; Martins, Isabel; Marques-Lopes, José; Wilson, Steven P. "Decrease in the expression of NMDA receptors in the nucleus tractus solitarii induces antinociception and increases blood pressure". (2012): https://www.authenticus.pt/P-010-NQR. Morgado, C.; Pereira-Terra, P.; Tavares, I.. "alpha-Lipoic acid normalizes nociceptive neuronal activity at the spinal cord of diabetic rats". Diabetes Obesity & Metabolism 13 8 (2011): 736-741. 10.1111/j.1463-1326.2011.01399.x Morgado, Carla; Silva, Liliana; Pereira-Terra, Patricia; Tavares, Isaura. "Changes in serotoninergic and noradrenergic descending pain pathways during painful diabetic neuropathy: The preventive action of IGF1". Neurobiology of Disease 43 1 (2011): 275-284. 10.1016/j.nbd.2011.04.001 Martins, I.; Cabral, L.; Pinto, A.; Wilson, S. P.; Lima, D.; Tavares, I.. "Reversal of inflammatory pain by HSV-1-mediated overexpression of enkephalin in the caudal ventrolateral medulla". European Journal of Pain 15 10 (2011): 1008-1014. 10.1016/j.ejpain.2011.04.007 Morgado, C.; Pereira-Terra, P.; Cruz, C. D.; Tavares, I.. "Minocycline completely reverses mechanical hyperalgesia in diabetic rats through microglia-induced changes in the expression of the potassium chloride co-transporter 2 (KCC2) at the spinal cord". Diabetes Obesity & Metabolism 13 2 (2011): 150-159. 10.1111/j.1463-1326.2010.01333.x Ribeiro, M. M. B.; Pinto, A.; Pinto, M.; Heras, M.; Martins, I.; Correia, A.; Bardaji, E.; Tavares, I.; Castanho, M.. "Inhibition of nociceptive responses after systemic administration of amidated kyotorphin". British Journal of Pharmacology 163 5 (2011): 964-973. 10.1111/j.1476-5381.2011.01290.x Pinho, Dora; Morato, Manuela; Couto, Marta R.; Marques-Lopes, Jose; Tavares, Isaura; Albino-Teixeira, Antonio. "Does Chronic Pain Alter the Normal Interaction Between Cardiovascular and Pain Regulatory Systems? Pain Modulation in the Hypertensive-Monoarthritic Rat". Journal of Pain 12 2 (2011): 194-204. 10.1016/j.jpain.2010.06.009 Ribeiro, Marta M. B.; Pinto, Antonia R. T.; Domingues, Marco M.; Serrano, Isa; Heras, Montserrat; Bardaji, Eduard R.; Tavares, Isaura; Castanho, Miguel A.. "Chemical Conjugation of the Neuropeptide Kyotorphin and Ibuprofen Enhances Brain Targeting and Analgesia". Molecular Pharmaceutics 8 5 (2011): 1929-1940. 10.1021/mp2003016 Pinho, Dora; António Albino-Teixeira; Isaura Tavares; Manuela Morato; Marta R Couto; Lopes, José Marques. "Does chronic pain alter the normal interaction between cardiovascular and pain regulatory systems? Pain modulation in hypertensive-monoarthritic rat". (2011): https://hdl.handle.net/10216/95005. Marques-Lopes, Jose; Pinho, Dora; Albino-Teixeira, Antonio; Tavares, Isaura. "The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A(5) noradrenergic cell group". Brain Research 1325 (2010): 41-52. 10.1016/j.brainres.2010.02.043 Martins, I.; Costa-Araujo, S.; Fadel, J.; Wilson, S. P.; Lima, D.; Tavares, I.. "Reversal of neuropathic pain by HSV-1-mediated decrease of noradrenaline in a pain facilitatory area of the brain". Pain 151 1 (2010): 137-145. 10.1016/j.pain.2010.06.027 Morgado, Carla; Terra, Patricia Pereira; Tavares, Isaura. "Neuronal hyperactivity at the spinal cord and periaqueductal grey during painful diabetic neuropathy: Effects of gabapentin". European Journal of Pain 14 7 (2010): 693-699. 10.1016/j.ejpain.2009.11.011 Tavares, Í.R.; Franzoi, A.C.; Araújo, A.Q.-C.. "Low-back pain in HTLV-I-associated myelopathy/tropical spastic paraparesis: Nociceptive or neuropathic". Spinal Cord 48 2 (2010): 134-137. http://www.scopus.com/inward/record.url?eid=2-s2.0-76649127065&partnerID=MN8TOARS. 10.1038/sc.2009.83 Pinho, Dora; António Albino-Teixeira; Isaura Tavares; Lopes, José Marques. "The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A5 noradrenergic cell group". (2010): https://repositorio-aberto.up.pt/handle/10216/101619. Gonçalves, Nuno; Rebelo, Sandra; Tavares, Isaura. "Fetal pain - neurobiological causes and consequences.". (2010): https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/637. 10.20344/amp.637 Gonçalves, Nuno; Rebelo, Sandra; Tavares, Isaura. "Fetal pain - neurobiological causes and consequences.". (2010): https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/637. Pinho, Dora; António Albino-Teixeira; Isaura Tavares; Lopes, José Marques. "The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A5 noradrenergic cell group". (2010): https://hdl.handle.net/10216/101619. Pinho, Dora; António Albino-Teixeira; Isaura Tavares; Lopes, José Marques. "The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A5 noradrenergic cell group". (2010): https://www.authenticus.pt/P-010-NR4. Marques-Lopes, J.; Pinto, M.; Pinho, D.; Morato, M.; Patinha, D.; Albino-Teixeira, A.; Tavares, I.. "MICROINJECTION OF ANGIOTENSIN II IN THE CAUDAL VENTROLATERAL MEDULLA INDUCES HYPERALGESIA". Neuroscience 158 4 (2009): 1301-1310. 10.1016/j.neuroscience.2008.11.044 Heinricher, M. M.; Tavares, I.; Leith, J. L.; Lumb, B. M.. "Descending control of nociception: Specificity, recruitment and plasticity". Brain Research Reviews 60 1 (2009): 214-225. 10.1016/j.brainresrev.2008.12.009 Marques Lopes, J; Pinto, M; Pinho, Dora; Morato, M; Patinha, D; Albino Teixeira, A; Isaura Tavares. "MICROINJECTION OF ANGIOTENSIN II IN THE CAUDAL VENTROLATERAL MEDULLA INDUCES HYPERALGESIA". (2009): https://repositorio-aberto.up.pt/handle/10216/102099. 10.1016/j.neuroscience.2008.11.044 Marques Lopes, J; Pinto, M; Pinho, Dora; Morato, M; Patinha, D; Albino Teixeira, A; Isaura Tavares. "MICROINJECTION OF ANGIOTENSIN II IN THE CAUDAL VENTROLATERAL MEDULLA INDUCES HYPERALGESIA". (2009): https://repositorio-aberto.up.pt/handle/10216/102099. 10.1016/j.neuroscience.2008.11.044 Pinto, Marta; Sousa, Marta; Lima, Deolinda; Tavares, Isaura. "Participation of mu-opioid, GABA(B), and NK1 receptors of major pain control medullary areas in pathways targeting the rat spinal cord: Implications for descending modulation of nociceptive transmission". Journal of Comparative Neurology 510 2 (2008): 175-187. 10.1002/cne.21793 Pinto, Marta; Castro, Ana Rita; Tshudy, Fabien; Wilson, Steven P.; Lima, Deolinda; Tavares, Isaura. "Opioids modulate pain facilitation from the dorsal reticular nucleus". Molecular and Cellular Neuroscience 39 4 (2008): 508-518. 10.1016/j.mcn.2008.07.008 Martins, I.; Pinto, M.; Wilson, S. P.; Lima, D.; Tavares, I.. "Dynamic of migration of HSV-1 from a medullary pronociceptive centre: antinociception by overexpression of the preproenkephalin transgene". European Journal of Neuroscience 28 10 (2008): 2075-2083. 10.1111/j.1460-9568.2008.06492.x Morgado, Carla; Pinto-Ribeiro, Filipa; Tavares, Isaura. "Diabetes affects the expression of GABA and potassium chloride cotransporter in the spinal cord: A study in streptozotocin diabetic rats". Neuroscience Letters 438 1 (2008): 102-106. 10.1016/j.neulet.2008.04.032 Morgado, Carla; Pinto-Ribeiro, Filipa; Tavares, Isaura. "Diabetes affects the expression of GABA and potassium chloride cotransporter in the spinal cord: a study in streptozotocin diabetic rats". (2008): http://hdl.handle.net/1822/61608. 10.1016/j.neulet.2008.04.032 Morgado, Carla; Pinto-Ribeiro, Filipa; Tavares, Isaura. "Diabetes affects the expression of GABA and potassium chloride cotransporter in the spinal cord: a study in streptozotocin diabetic rats". (2008): http://hdl.handle.net/1822/61608. 10.1016/j.neulet.2008.04.032 Morgado, C.; Tavares, I.. "C-fos expression at the spinal dorsal horn of streptozotocin-induced diabetic rats". Diabetes-Metabolism Research and Reviews 23 8 (2007): 644-652. 10.1002/dmrr.751 Pinto, M.; Lima, D.; Tavares, I.. "Neuronal activation at the spinal cord and medullary pain control centers after joint stimulation: A c-fos study in acute and chronic articular inflammation". Neuroscience 147 4 (2007): 1076-1089. 10.1016/j.neuroscience.2007.05.019 Tavares, I.; Lima, D.. "From neuroanatomy to gene therapy: searching for new ways to manipulate the supraspinal endogenous pain modulatory system". Journal of Anatomy 211 2 (2007): 261-268. 10.1111/j.1469-7580.2007.00759.x Pinho, Dora; Morato, Manuela; Sousa, Teresa; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "Hipertensão e hipoalgesia: papel do bolbo raquidiano ventrolateral caudal e do sistema GABAérgico espinhal.". (2007): https://repositorio-aberto.up.pt/handle/10216/94725. Pinho, Dora; Morato, Manuela; Sousa, Teresa; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "Hipertensão e hipoalgesia: papel do bolbo raquidiano ventrolateral caudal e do sistema GABAérgico espinhal.". (2007): https://repositorio-aberto.up.pt/handle/10216/94725. Pinho, Dora; Morato, Manuela; Sousa, Teresa; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "Hipertensão e hipoalgesia: papel do bolbo raquidiano ventrolateral caudal e do sistema GABAérgico espinhal.". (2007): https://www.authenticus.pt/P-010-NR5. Almeida, A.; Leite-Almeida, H.; Tavares, I.. "Medullary control of nociceptive transmission: Reciprocal dual communication with the spinal cord". Drug Discovery Today: Disease Mechanisms 3 3 (2006): 305-312. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847060105&partnerID=MN8TOARS. 10.1016/j.ddmec.2006.09.001 Castro, A. R.; Pinto, M.; Lima, D.; Tavares, I.. "Secondary hyperalgesia in the monoarthritic rat is mediated by GABA(B) and NK1 receptors of spinal dorsal horn neurons: A behavior and c-fos study". Neuroscience 141 4 (2006): 2087-2095. 10.1016/j.neuroscience.2006.05.048 Pinho, D; Sousa, T; Morato, M; Tavares, I; Albino-Teixeira, A. "Lesion of the caudal ventrolateral medulla prevents the induction of hypertension by adenosine receptor blockade in rats". Brain Research 1073 (2006): 374-382. 10.1016/j.brainres.2005.12.098 Morato, M; Pinho, D; Sousa, T; Tavares, I; Albino-Teixeira, A. "Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla". Journal of Neuroscience Research 83 4 (2006): 647-655. 10.1002/jnr.20770 Castro, AR; Morgado, C; Lima, D; Tavares, I. "Differential expression of NK1 and GABA(B) receptors in spinal neurones projecting to antinociceptive or pronociceptive medullary centres". Brain Research Bulletin 69 3 (2006): 266-275. 10.1016/j.brainresbull.2005.12.004 Pinto, Marta; Lima, Deolinda; Tavares, Isaura. "Correlation of noxious evoked c-fos expression in areas of the somatosensory system during chronic pain: Involvement of spino-medullary and intra-medullary connections". Neuroscience Letters 409 2 (2006): 100-105. 10.1016/j.neulet.2006.08.031 Almeida, Armando; Almeida, Hugo Leite; Tavares, Isaura. "Medullary control of nociceptive transmission: reciprocal dual communication with the spinal cord". (2006): http://hdl.handle.net/1822/5947. 10.1016/j.ddmec.2006.09.001 Almeida, Armando; Almeida, Hugo Leite; Tavares, Isaura. "Medullary control of nociceptive transmission: reciprocal dual communication with the spinal cord". (2006): http://hdl.handle.net/1822/5947. 10.1016/j.ddmec.2006.09.001 Castro, Ana Rita Fernandes Barros; Morgado, Carla; Lima, Deolinda; Tavares, Isaura. "Differential expression of NK1 and GABAB receptors in spinal neurons that project to an antinociceptive area or a pronociceptive region of medulla oblongata". Brain Res Bull 69 3 (2006): 266-275. Published Castro, AR; Pinto, M; Lima, D; Tavares, I. "Imbalance between the expression of NK1 and GABA(B) receptors in nociceptive spinal neurons during secondary hyperalgesia: A c-Fos study in the monoarthritic rat". Neuroscience 132 4 (2005): 905-916. 10.1016/j.neuroscience.2005.01.048 Castro, Ana Rita Fernandes Barros; Costa, JA; Costa, JL; Tavares, Isaura; Lima, Deolinda. "Chronic pain is associated with low discrimination ability of lamina I neurons projecting to the caudal ventrolateral medulla". Sinapse 5 (2005): 94-98. Published Tavares, I.. "The molecular metamorphosis of embryology: Implications for medical education". Medical Education 38 5 (2004): 544-544. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442567966&partnerID=MN8TOARS. 10.1111/j.1365-2929.2004.01923.x Castro, AR; Pinto, M; Lima, D; Tavares, I. "Nociceptive spinal neurons expressing NKI and GABA(B) receptors are located in lamina I". Brain Research 1003 1-2 (2004): 77-85. 10.1016/j.brainres.2003.12.027 Cobos, A; Lima, D; Almeida, A; Tavares, I. "Brain afferents to the lateral caudal ventrolateral medulla: A retrograde and anterograde tracing study in the rat". NEUROSCIENCE (2003): https://www.authenticus.pt/P-000-K75. 10.1016/s0306-4522(03)00209-4 Pinto, M; Lima, D; Castro-Lopes, J; Tavares, I. "Noxious-evoked c-fos expression in brainstem neurons immunoreactive for GABA(B), mu-opioid and NK-1 receptors". European Journal of Neuroscience 17 7 (2003): 1393-1402. 10.1046/j.1460-9568.2003.02586.x Cobos, Angeles; Lima, Deolinda; Almeida, Armando; Tavares, Isaura. "Brain afferents to the lateral caudal ventrolateral medulla : a retrograde and anterograde tracing study in the rat". (2003): http://hdl.handle.net/1822/1663. 10.1016/S0306-4522(03)00209-4 Cobos, Angeles; Lima, Deolinda; Almeida, Armando; Tavares, Isaura. "Brain afferents to the lateral caudal ventrolateral medulla : a retrograde and anterograde tracing study in the rat". (2003): http://hdl.handle.net/1822/1663. 10.1016/S0306-4522(03)00209-4 Castro, Ana Rita Fernandes Barros; Pinto, Marta; Lima, Deolinda; Tavares, Isaura. "Expressão de receptores NK1 e GABAB em neurónios nociceptivos da medula espinhal do rato". Revista DOR 11 (2003): 10-14. Published Tavares, I; Lima, D. "The caudal ventrolateral medulla as an important inhibitory modulator of pain transmission in the spinal cord". Journal of Pain 3 5 (2002): 337-346. 10.1054/jpai.2002.127775 Lima, D; Albino-Teixeira, A; Tavares, I. "The caudal medullary ventrolateral reticular formation in nociceptive-cardiovascular integration. An experimental study in the rat". Experimental Physiology 87 2 (2002): 267-274. 10.1113/eph8702354 Almeida, A; Cobos, A; Tavares, I; Lima, D. "Brain afferents to the medullary dorsal reticular nucleus: a retrograde and anterograde tracing study in the rat". European Journal of Neuroscience 16 1 (2002): 81-95. 10.1046/j.1460-9568.2002.02058.x Tavares, I; Lima, D. "Are genetic differences crucial for the definition of pain circuits?". Journal of Pain 3 5 (2002): 358-359. 10.1054/jpai.2002.127778 Almeida, Armando; Cobos, Angeles; Tavares, Isaura; Lima, Deolinda. "Brain afferents to the medullary dorsal reticular nucleus: a retrograde and anterograde tracing study in the rat". (2002): http://hdl.handle.net/1822/1655. 10.1046/j.1460-9568.2002.02058.x Almeida, Armando; Cobos, Angeles; Tavares, Isaura; Lima, Deolinda. "Brain afferents to the medullary dorsal reticular nucleus: a retrograde and anterograde tracing study in the rat". (2002): http://hdl.handle.net/1822/1655. 10.1046/j.1460-9568.2002.02058.x Gamboa-Esteves, FO; Tavares, I; Almeida, A; Batten, TFC; McWilliam, PN; Lima, D. "Projection sites of superficial and deep spinal dorsal horn cells in the nucleus tractus solitarii of the rat". Brain Research 921 1-2 (2001): 195-205. 10.1016/S0006-8993(01)03118-3 Almeida, A; Tavares, I; Lima, D. "Reciprocal connections between the medullary dorsal reticular nucleus and the spinal dorsal horn in the rat". European Journal of Pain-London 4 4 (2000): 373-387. 10.1053/eujp.2000.0193 Tavares, I; Almeida, A; Albino-Teixeira, A; Lima, D. "Lesions of the caudal ventrolateral medulla block the hypertension-induced inhibition of noxious-evoked c-fos expression in the rat spinal cord.". European journal of pain (London, England) 1 2 (1997): 149-60. 10.1016/S1090-3801(97)90073-2 Tavares, I.. "The pontine A5 noradrenergic cells which project to the spinal cord dorsal horn are reciprocally connected with the caudal ventrolateral medulla in the rat". European Journal of Neuroscience 9 11 (1997): 2452-2461. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031283088&partnerID=MN8TOARS. 10.1111/j.1460-9568.1997.tb01662.x Tavares, I; Lima, D; Coimbra, A. "The ventrolateral medulla of the rat is connected with the spinal cord dorsal horn by an indirect descending pathway relayed in the A(5) noradrenergic cell group". Journal of Comparative Neurology 374 1 (1996): 84-95. 10.1002/(SICI)1096-9861(19961007)374:1<84::AID-CNE6>3.0.CO;2-J TAVARES, I; ALBINOTEIXEIRA, A; LIMA, D. "HYPERTENSION INHIBITS NOXIOUS-EVOKED C-FOS EXPRESSION IN THE RAT SPINAL-CORD". Neuroreport 6 12 (1995): 1664-1668. 10.1097/00001756-199508000-00018 Almeida, A.; Tavares, I.; Lima, D.. "Projection sites of superficial or deep dosal horn in te dorsal reticular nucleus". NeuroReport 6 9 (1995): 1245-1248. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029009336&partnerID=MN8TOARS. Almeida, A.; Tavares, I.; Lima, D.. "Still more specificity in the net". NeuroReport 6 9 (1995): 1235-1235. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646047040&partnerID=MN8TOARS. 10.1097/00001756-199506090-00001 CASTROLOPES, JM; TAVARES, I; TOLLE, TR; COIMBRA, A. "CARRAGEENAN-INDUCED INFLAMMATION OF THE HIND FOOT PROVOKES A RISE OF GABA-IMMUNOREACTIVE CELLS IN THE RAT SPINAL-CORD THAT IS PREVENTED BY PERIPHERAL NEURECTOMY OR NEONATAL CAPSAICIN TREATMENT". Pain 56 2 (1994): 193-201. 10.1016/0304-3959(94)90094-9 Tavares, I.; Lima, D.. "Descending projections from the caudal medulla oblongata to the superficial or deep dorsal horn of the rat spinal cord". Experimental Brain Research 99 3 (1994): 455-463. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028362571&partnerID=MN8TOARS. 10.1007/BF00228982 Tavares, I.; Lima, D.; Batten, T.F.C.; Coimbra, A.. "Is the pathway connecting the caudal ventrolateral medulla with the dorsal horn of the spinal cord of the rat noradrenergic?". Regional Anesthesia 18 4 SUPPL. (1993): http://www.scopus.com/inward/record.url?eid=2-s2.0-0027220736&partnerID=MN8TOARS. TAVARES, I; LIMA, D; COIMBRA, A. "NEURONS IN THE SUPERFICIAL DORSAL HORN OF THE RAT SPINAL-CORD PROJECTING TO THE MEDULLARY VENTROLATERAL RETICULAR-FORMATION EXPRESS C-FOS AFTER NOXIOUS-STIMULATION OF THE SKIN". Brain Research 623 2 (1993): 278-286. 10.1016/0006-8993(93)91438-X CASTROLOPES, JM; TAVARES, I; COIMBRA, A. "GABA DECREASES IN THE SPINAL-CORD DORSAL HORN AFTER PERIPHERAL NEURECTOMY". Brain Research 620 2 (1993): 287-291. 10.1016/0006-8993(93)90167-L ALMEIDA, A; TAVARES, I; LIMA, D; COIMBRA, A. "DESCENDING PROJECTIONS FROM THE MEDULLARY DORSAL RETICULAR NUCLEUS MAKE SYNAPTIC CONTACTS WITH SPINAL-CORD LAMINA-I CELLS PROJECTING TO THAT NUCLEUS - AN ELECTRON-MICROSCOPIC TRACER STUDY IN THE RAT". Neuroscience 55 4 (1993): 1093-1106. 10.1016/0306-4522(93)90323-8 CASTROLOPES, JM; TAVARES, I; TOLLE, TR; COITO, A; COIMBRA, A. "INCREASE IN GABAERGIC CELLS AND GABA LEVELS IN THE SPINAL-CORD IN UNILATERAL INFLAMMATION OF THE HINDLIMB IN THE RAT". EUROPEAN JOURNAL OF NEUROSCIENCE (1992): https://www.authenticus.pt/P-001-PPH. 10.1111/j.1460-9568.1992.tb00877.x
Preprint	Bruno Daniel Carneiro; Isaura Tavares. "Transcranial Magnetic Stimulation to Treat Neuropathic Pain: A Bibliometric Analysis". 2024. https://doi.org/10.20944/preprints202401.1089.v1. 10.20944/preprints202401.1089.v1 Ana Rita Soares; Sandra Soares; Tânia Brandão; Ricardo João Teixeira; Isaura Tavares. "Development and use of a meditation app (Med@Med) for and by medical students: motivations, adherence and emotional effects (Preprint)". 2023. https://doi.org/10.2196/preprints.50333. 10.2196/preprints.50333
Thesis / Dissertation	Amorim, Diana. "Pronociception in experimental monoarthritis: the role of galanin in descending pathways". PhD, 2014. http://hdl.handle.net/1822/35378. Louçano, Marta. "Descending pain modulation in a Kaolin-induced hydrocephalus rat model". Master, 2014. http://hdl.handle.net/10400.22/6383. Louçano, Marta. "Descending pain modulation in a Kaolin-induced hydrocephalus rat model". Master, 2014. http://hdl.handle.net/10400.22/6383. Amorim, Diana. "Pronociception in experimental monoarthritis: the role of galanin in descending pathways". PhD, 2014. http://hdl.handle.net/1822/35378. Silva, Liliana de Jesus Vieira da. "Central effects of insulin and IGF1 in diabetic neuropathy". Master, 2010. http://hdl.handle.net/10773/8778.

Other

Other output

Spinal Cord Injury and Complications Related to Neuraxial Anaesthesia Procedures: A Systematic Review. 2023. Pozza, DH; Tavares, I; Cruz, CD; Fonseca, S.
10.3390/ijms24054665
António Coimbra:pioneiro da investigação experimental em dor em Portugal.. Os aspetos académico,científico e pessoal da vida deste Professor Catedrático da FMUP e o impacto dos seus ensinamentos na Escola de que foi autor.. 2023. Mariana Patela; Tavares, Isaura; Ricon Ferraz, Amélia. http://creativecommons.org/licenses/by-nc-nd/4.0/.
Research in Mindfulness Interventions for Patients With Fibromyalgia: A Critical Review. 2022. Leca, S; Tavares, I.
10.3389/fnint.2022.920271
Was it something I ate? Understanding the bidirectional interaction of migraine and appetite neural circuits. 2021. Martins Oliveira, M; Tavares, I; Goadsby, PJ.
10.1016/j.brainres.2021.147629
Chronic Pain After Spinal Cord Injury: Is There a Role for Neuron-Immune Dysregulation?. 2020. Chambel, SS; Tavares, I; Cruz, CD.
10.3389/fphys.2020.00748
Can the dopaminergic-related effects of general anesthetics be linked to mechanisms involved in drug abuse and addiction?. 2015. Melo, A; Tavares, I; Sousa, N; Pego, JM. https://www.authenticus.pt/P-00G-DFS.
10.1111/aas.12530
"Hotheaded": The role OF TRPV1 in brain functions. 2014. Martins, D; Tavares, I; Morgado, C. https://www.authenticus.pt/P-009-KCP.
10.1016/j.neuropharm.2014.05.034
FETAL PAIN Neurobiological Causes and Consequences. 2010. Goncalves, N; Rebelo, S; Tavares, I. https://www.authenticus.pt/P-003-6T5.
The molecular metamorphosis of embryology: implications for medical education. 2004. Tavares, I. https://www.authenticus.pt/P-000-ANH.
10.1046/j.1365-2929.2004.01923.x
STILL MORE SPECIFICITY IN THE NET. 1995. ALMEIDA, A; TAVARES, I; LIMA, D. https://www.authenticus.pt/P-008-PSV.

Activities

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2021/06 - Current	Research in fibromyalgia and Mindfulness: still at ground zero? Supervisor	Mestrado Integrado em Medicina da Faculdade de Medicina da Universidade do Porto (Master) Universidade do Porto Faculdade de Medicina, Portugal
2017/06 - Current	The noradrenergic system in an animal model of hydrocephalus: implications for descending pain modulation Supervisor	Programa Doutoral em Biologia Avançada (PhD) Universidade de Vigo, Spain
2011/02 - Current	General anesthetics in cognitive modulation Co-supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2017/06 - 2020/12	Modulação descendente da dor na neuropatia induzida por citostáticos Supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2017/05 - 2020/12	Hiperalgesia induzida por administração de opióides Co-supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD)
2013/07 - 2018/07	Appetite neurobiology and modulation of nociceptive trigeminovascular inputs-Studies to understand migraine pathophysiology Co-supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2013/05 - 2016/10	Trabalho de investigação relativo ao projeto Europeu REDDSTAR (Repair of Diabetic Damage by Stromal Cell Administration) que envolveu 9 parceiros europeus e em que desempenhei funções de coordenador português. Supervisor of Sandra Marisa Oliveira	Universidade do Porto Faculdade de Medicina, Portugal
2011/05 - 2016/07	O papel do Bolbo Rostroventromedial na Neuropatia Diabética Dolorosa Supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2011/03 - 2014/03	Pain facilitation in chronic pain: descending spinal modulation by the dorsal reticular nucleus Co-supervisor	Universidade do Minho Escola de Medicina, Portugal
2006/05 - 2012/01	Terapia génica para manipulação do sistema supraspinal endógeno de controlo da dor Supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2011/09	O sistema somatossensitivo do rato com neuropatia diabética Supervisor	Programa Internacional de Doutoramento em Neurociências (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2008/01 - 2011/06	Hipertensão e dor: estudos de mecanismos centrais num modelo experimental de dor crónica Co-supervisor	Programa Internacional de Doutoramento em Neurociências da Universidade do Porto (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2005/01 - 2008/02	Modificações do sistema endógeno de controlo da dor em processos dolorosos agudos e crónicos Supervisor	Universidade do Porto Faculdade de Medicina, Portugal
2004/01 - 2006/05	Expressão dos receptores NK1 e GABAB em neurónios nociceptivos espinhais: ações do sistema supraspinhal endógeno de controlo da dor Supervisor of Ana Rita Barros Fernandes	Universidade do Porto Faculdade de Medicina, Portugal

Distinctions

Award

2021	Prémio Grunenthal Dor 2020 Fundação Grünenthal, Portugal
2018	Prémio Grunenthal Dor 2017 Fundação Grünenthal, Portugal