???global.info.a_carregar???
Identification

Personal identification

Full name
Joana Margarida Pereira Vieira

Citation names

  • Vieira, Joana
  • Pereira-Vieira, Joana

Author identifiers

Ciência ID
4B16-61C9-8A9F
ORCID iD
0000-0002-5413-3445

Addresses

  • Instituto de Investigação em Ciências da Vida e Saúde (ICVS), Escola de Medicina – Universidade do Minho, Campus de Gualtar , 4710-057, Gualtar, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1) Upper intermediate (B2)
French Beginner (A1) Beginner (A1)
Education
Degree Classification
2019/10/01 - 2025/01/09
Concluded
Ciência da Saúde (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
"Exploration of glucose metabolism in acute myeloid leukemia: effect of 3- bromopyruvate in the response to chemotherapy" (THESIS/DISSERTATION)
2015/10 - 2017/05
Concluded
Genética Molecular (Mestrado)
Universidade do Minho, Portugal
"Molecular Mechanisms Involved in 3-Bromopyruvate Effect in Colorectal Cancer Cell Lines" (THESIS/DISSERTATION)
2009/09 - 2012/07
Concluded
Biologia Aplicada (Licenciatura)
Universidade do Minho, Portugal
Affiliation

Science

Category
Host institution
Employer
2025/01/01 - 2025/12/31 Researcher (Research) Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/10/01 - 2025/01/09 Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2024/01/01 - 2024/12/31 Researcher (Research) Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/01/15 - 2019/09/30 Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/06 - 2017/05 Research Trainee (Research) Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Projects

Grant

Designation Funders
2025/01/01 - 2025/12/31 Unraveling the potential of chromene compounds as novel epigenetic therapeutic agents for acute myeloid leukemia
Bolsas de Investigação em Oncologia LPCC-NRN 2025
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte
Ongoing
2019/09/01 - 2025/01/09 Exploration of glucose metabolism in acute myeloid leukemia: effect of 3- bromopyruvate in the response to chemotherapy
SFRH/BD/146065/2019
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2024/01/01 - 2024/12/31 3-Bromopyruvate treatment boosts the response of Acute Myeloid Leukemia (AML) cells to chemotherapy: validation in the in vivo chicken embryo model of AML
Bolsas de Investigação em Oncologia LPCC-NRN 2024
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte
Ongoing
2018/01/15 - 2019 Anticancer effect of 3-Bromopyruvate (3BP) in animal model systems of leukemia
UMINHO/BI/57/2018
Research Fellow
Universidade do Minho Escola de Medicina, Portugal

Universidade do Minho Escola de Ciências, Portugal
Concluded
Outputs

Publications

Conference poster
  1. Pereira-Vieira, Joana. "NOVEL IMIDAZOLE-BASED MOLECULES AS ANTICANCER AGENTS FOR ACUTE MYELOID LEUKAEMIA (AML)". Paper presented in International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC 2025), 2025.
  2. Pereira-Vieira, Joana; Weber, Daniela; Sónia Pires Celeiro; Granja, Sara; Reis, Rui Manuel; Moura, Rute S; Queiros, Odilia; et al. "Treatment with 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia". Paper presented in Annual Congress of EACR, 2025.
  3. Pereira-Vieira, Joana; Granja, Sara; Sónia Pires Celeiro; Ana Catarina Barbosa Matos; Ana Preto; Queiros, Odilia; Ko, YH; Casal, Margarida; Maria de Fátima Monginho Baltazar. "3-Bromopiruvato aumenta o efeito da quimioterapia na leucemia mieloide aguda por um mecanismo mediado por ROS". Paper presented in 6ºENJIC – LPCC, 2024.
  4. Pereira-Vieira, Joana; Weber, Daniela; Silva, Sâmia; Ana Catarina Barbosa Matos; Granja, Sara; Reis, Rui Manuel; Ko, YH; et al. "Targeting glucose metabolism in acute myeloid leukemia (AML) chemoresistance". Paper presented in 6th ASPIC International Congress, 2024.
  5. Pereira-Vieira, Joana; Maria Barreto-Gonçalves; Ana Catarina Barbosa Matos; Queiros, Odilia; Ko, YH; Casal, Margarida; Maria de Fátima Monginho Baltazar. "Characterization of metabolic profile of acute myeloid leukaemia cells resistant to chemotherapy". Paper presented in Cancer Metabolism EACR, 2022.
  6. Pereira-Vieira, Joana; Sónia Pires Celeiro; Granja, Sara; Ana Catarina Barbosa Matos; Ana Preto; Queiros, Odilia; Ko, YH; Casal, Margarida; Maria de Fátima Monginho Baltazar. "Targeting glycolytic metabolism as a therapeutic strategy for Acute Myeloid Leukemia". Paper presented in EACR, Virtual Conference, 2021.
  7. Pereira-Vieira, Joana; Celeiro, Sónia Pires; Granja, Sara; Ana Catarina Barbosa Matos; Ko, YH; Ana Preto; Queiros, Odilia; Casal, Margarida; Maria de Fátima Monginho Baltazar. "3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense". Paper presented in LPCC, Virtual Conference, 2020.
  8. Pereira-Vieira, Joana; Granja, Sara; Ana Catarina Barbosa Matos; Ko, YH; Ana Preto; Queiros, Odilia; Casal, Margarida; Maria de Fátima Monginho Baltazar. "Non-toxic concentrations of 3-bromopyruvate sensitize acute myeloid leukemia (AML) cells to chemotherapy by inducing oxidative stress". Paper presented in EACR-AACR with ASPIC, Lisbon, 2020.
  9. Pereira-Vieira, Joana; Sara Granja; Ana Catarina Barbosa Matos; Ko, YH; Ana Preto; Casal, Margarida; Maria de Fátima Monginho Baltazar. "3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy". Paper presented in 6th Annual ISCaM (International Society for Cancer Metabolism) Meeting, 2019.
  10. Pereira-Vieira, Joana; Sara Granja; Ana Catarina Barbosa Matos; Ko, YH; Ana Preto; Casal, Margarida; Maria de Fátima Monginho Baltazar. "3-Bromopyruvate sensitizes Acute Myeloid Leukemia cell lines to chemotherapy". Paper presented in 26th Porto Cancer Meeting, 2019.
  11. Vieira, Joana. "Monocarboxylate transporters expression is influenced by different extracellular conditions determining the effect of 3-bromopyruvate in colorectal cancer cells.". Paper presented in 3rd ASPIC Interntional Congress, 2018.
  12. Vieira, Joana; Barbosa, Ana; Moreira, Roxana; Casal, Margarida; Queirós, Odília. "3-Bromopyruvate induces cytotoxicity and inhibits glycolysis and migratory capacity in glioblastomas and colorectal cancer cell lines". Paper presented in 2nd ASPIC Interntional Congress, 2016.
Journal article
  1. Pereira-Vieira, Joana; Granja, Sara; Celeiro, Sónia Pires; Barbosa-Matos, Catarina; Preto, Ana; Queirós, Odília; Ko, Young Hee; Casal, Margarida; Baltazar, Fátima. "3-Bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by a pro-oxidant mechanism". Free Radical Biology and Medicine 234 (2025): 192-202. https://doi.org/10.1016/j.freeradbiomed.2025.04.017.
    Open access • Published • 10.1016/j.freeradbiomed.2025.04.017
  2. Julieta Afonso; Catarina Barbosa-Matos; Ricardo Silvestre; Joana Pereira-Vieira; Samuel Martins Gonçalves; Camille Mendes-Alves; Pier Parpot; et al. "Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect". Cancers (2024): https://www.mdpi.com/2072-6694/16/7/1418.
    10.3390/cancers16071418
  3. Joana Pereira-Vieira; Daniela D. Weber; Sâmia Silva; Catarina Barbosa-Matos; Sara Granja; Rui Manuel Reis; Odília Queirós; et al. "Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia". Pharmaceutics (2024): https://www.mdpi.com/1999-4923/16/4/442.
    10.3390/pharmaceutics16040442
  4. Pereira-Vieira, Joana; Azevedo-Silva, João; Preto, Ana; Casal, Margarida; Queirós, Odília. "MCT1, MCT4 and CD147 expression and 3-bromopyruvate toxicity in colorectal cancer cells are modulated by the extracellular conditions". Biological Chemistry 0 0 (2019): http://dx.doi.org/10.1515/hsz-2018-0411.
    10.1515/hsz-2018-0411
Thesis / Dissertation
  1. "Exploration of glucose metabolism in acute myeloid leukemia: effect of 3- bromopyruvate in the response to chemotherapy". PhD, Universidade do Minho Escola de Medicina, 2025.
  2. Vieira, Joana. "Molecular Mechanisms Involved in 3-Bromopyruvate Effect in Colorectal Cancer Cell Lines". Master, Universidade do Minho Centro de Biologia Molecular e Ambiental, 2017.
  3. Vieira, Joana. "Impacto da Sobreexpressão da IL-10 na Hematopoiese". Degree, Universidade do Minho, 2012.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/01/29 Altered Metabolism in Cancer ADVANCED COURSE on Oncobiology 9th Ed
CESPU (Gandra, Portugal)
2024/01/22 Exploration of glucose metabolism in acute myeloid leukemia: effect of 3- bromopyruvate in the response to chemotherapy ICVS seminar
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde (Braga, Portugal)
2022/07/05 3-Bromopyruvate - a therapeutic strategy for Acute Myeloid Leukemia? Ciência Falada
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde (Braga, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2025/03 - 2026/02 Cancer in Perspective - World Cancer Day (2025/03 - 2026/02)
Meeting (Member of the Organising Committee)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2025/07 - 2025/09/26 European Researchers' Night (ERN) (2025/07 - 2025/09/26)
Meeting (Member of the Organising Committee)
Universidade do Minho Escola de Ciências, Portugal
2011/09 - 2012/03 Comissão Organizadora das XIII Jornadas de Biologia Aplicada, "A Vida em Revolução" (2011/09 - 2012/03) Universidade do Minho, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2025/09/24 - 2025/09/24 7º ENJIO tem como objetivo principal a promoção do debate e a partilha de novas ideias e conhecimentos, de forma a aproximar os investigadores em oncologia, potenciar a sinergia entre estes e permitir um ambiente colaborativo e produtivo do trabalho a desenvolver. O tema das expectativas de futuro e dos problemas que os investigadores atravessam durante o seu percurso científico serão debatidos entre jovens investigadores no início da sua carreira e reconhecidos investigadores com percursos de sucesso na área da oncologia.
Conference
7º ENCONTRO NACIONAL DE JOVENS INVESTIGADORES EM ONCOLOGIA (ENJIO), PORTO (PORTUGAL)
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2025/06/30 - 2025/06/30 Biblioteca Humana” (Human Library), ELOS Project – LPCC & D8 Solution Company
Other
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2025/06/16 - 2025/06/19 The 2025 Annual Congress of the European Association for Cancer Research was four day congress dedicated to basic, preclinical and translational cancer research across a wide breadth of topics.
Congress
EACR 2025 Congress: Innovative Cancer Science, Lisbon (Portugal)
European Association For Cancer Research, United Kingdom

Associação Portuguesa de Investigação em Cancro, Portugal
2025/01/13 - 2025/01/13 Biblioteca Humana” (Human Library), ELOS Project – LPCC & Maximinos High School
Other
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2024/09/24 - 2024/09/24 6º ENJIO teve como objetivo principal a promoção do debate e a partilha de novas ideias e conhecimentos, de forma a aproximar os investigadores em oncologia, potenciar a sinergia entre estes e permitir um ambiente colaborativo e produtivo do trabalho a desenvolver.
Conference
6º ENCONTRO NACIONAL DE JOVENS INVESTIGADORES EM ONCOLOGIA (ENJIO), PORTO (PORTUGAL)
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2022/10/11 - 2022/10/13 The EACR Conference on Cancer Metabolism gathered top experts in the field in Bilbao, Spain to discuss the metabolic alterations in tumours and how we can exploit this to treat cancer.
Conference
Cancer Metabolism EACR, Bilbao (Spain)
European Association For Cancer Research, United Kingdom
2022/06/30 - 2022/07/01 The ASPIC Congress holded another rewarding meeting, which also represented an excellent opportunity to physically meet each other again and to learn, face-to-face, about new developments in cancer research, share results and discoveries through oral presentations and through a big and participative poster session.
Congress
5th ASPIC International Congress, IPO-Porto (Portugal)
Associação Portuguesa de Investigação em Cancro, Portugal
2021/06/09 - 2021/06/21 The European Association for Cancer Research (EACR) held its annual congress virtually from June 9-12, 2021, focusing on "Innovative Cancer Science: Better Outcomes Through Research"
Congress
Innovative Cancer Science: Better Outcomes Through Research, EACR, Virtual Congress
European Association For Cancer Research, United Kingdom
2020/09/25 - 2020/09/25 Cancer Biology: From Basic To Translational Research aimed to get together national and international researchers in basic and clinical oncology to present the most promising results that might have a clinical impact in the oncology field. Different thematic of tumor complexity (genetics, biomarkers, tumor micro-environment, tumor metabolism, and new potential therapeutic targets) were addressed, as well as the application of knowledge to improve the diagnosis or treatments of cancer patients.
Conference
CANCER BIOLOGY: FROM BASIC TO TRANSLATIONAL RESEARCH, Virtual conference
Liga Portuguesa Contra o Cancro, Portugal
2020/09/24 - 2020/09/24 ENJIO teve como objetivo principal a promoção do debate e a partilha de novas ideias e conhecimentos, de forma a aproximar os investigadores em oncologia, potenciar a sinergia entre estes e permitir um ambiente colaborativo e produtivo do trabalho a desenvolver.
Conference
2º ENCONTRO NACIONAL DE JOVENS INVESTIGADORES EM ONCOLOGIA (ENJIO), Porto (Portugal)
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2020/03/02 - 2020/03/04 The EACR-AACR-ASPIC Conference on Tumor Microenvironment (TME) brought together thought leaders spanning the breadth of TME, immune-oncology, computational biology and biomedical technology disciplines to discuss novel approaches to identify critical mechanisms regulating the crosstalk in these tumor ecosystems.
Conference
EACR-AACR-ASPIC 2020 Conference: Tumor Microenvironment, Lisbon (Portugal)
European Association For Cancer Research, United Kingdom

American Association for Cancer Research, United States

Associação Portuguesa de Investigação em Cancro, Portugal
2019/10/17 - 2019/10/19 6th Annual ISCaM Meeting have set a comprehensive program that tackles the many faces of cancer metabolism, highlighting the recent advances in the field and the road ahead for clinical translation.
Congress
6th Annual ISCaM (International Society for Cancer Metabolism) Meeting, Braga-Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2019/05/02 - 2019/05/03 The Cancer Ecosystem: From Research to Pathology and Treatment
Congress
26th Porto Cancer Meeting, Porto (Portugal)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/05/10 - 2018/05/11 The 3rd ASPIC Congress gave cancer researchers a stage where they speak to the inside and to the outside of the community, to patient’s associations and to the public, on their successes but also on the many still unsolved questions.
Congress
3rd ASPIC International Congress, Fundação Calouste Gulbenkian-Lisbon (Portugal)
Associação Portuguesa de Investigação em Cancro, Portugal
2016/04/28 - 2016/04/29 The 2nd ASPIC International Congress was an excellent opportunity to share knowledge on the new developments at basic and clinical levels in cancer immunology, tumor biology, signaling pathways and radio-biology.
Congress
2nd ASPIC International Congress, IPO-Porto (Portugal)
Associação Portuguesa de Investigação em Cancro, Portugal
2012/05/11 - 2012/05/18 Colaboração na iniciativa da Escola de Ciências dirigida aos alunos e professores dos ensinos pré-escolar, básico e secundário, auxiliando na receção e acompanhamento dos participantes durante as atividades desenvolvidas.
Other
Festa da Ciência
Universidade do Minho, Portugal

Association member

Society Organization name Role
2016/03/02 - Current European Association for CancerResearch (EACR) Member
2016/03/02 - Current Portuguese Association for CancerResearch (ASPIC) Member

Mentoring / Tutoring

Topic Student name
2025/08/18 - 2025/10/17 Internship — Medical School Hannover Lisa Klingel, MSc student
2025/02 - 2025/10 MSc project Marta Martins, MSc student
2023/09 - 2023/11 MSc project Filipa Pimentel, Medicine student
2023/08 - 2023/09 Laboratory rotation Joana Sampaio, Medicine student
2022/05 - 2022/06 BSc project Mariana Gonçalves, Undergraduate student
2021/11 - 2021/12 Laboratory rotation Anabela Ferreia, MSc. student
Distinctions

Award

2020 Best Poster
Liga Portuguesa Contra o Cancro, Portugal

Other distinction

2025 Top-scoring abstracts
Associação Portuguesa de Investigação em Cancro, Portugal