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Diogo Alpuim Costa (MD; MSc) is a PhD Student (Breast Cancer and Microbiota fields) at NOVA Medical School, Head of the Oncology Department and Medical Day Hospital at Hospital de Cascais, Head of the Haemato-Oncology Department at CUF Cascais/Sintra, Medical Oncologist at CUF Descobertas and Underwater and Hyperbaric Physician at Centro Hiperbárico de Cascais and Hospital da Luz Lisboa. Lieutenant Commander Navy Doctor with several national and international naval missions: operational training, search and rescue, medical support to a real scenario of natural catastrophe (Madeira 2010) and as a Head of the Health Department at Portuguese Navy Tall Ship NRP "Sagres" during the Celebration Programme for the Fifth Centenary of Fernão de Magalhães (Magellan) world´s first Circumnavigation. Diogo Alpuim Costa received a Medical Degree at Faculdade deversidade de Lisboa (FML), a Master's Degree in Hyperbaric and Underwater Medicine at FML, and Postgraduate Education in Pain Management, Sports Medicine, Medicina da Uni and Military Health. He completed the residency in Medical Oncology at Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E., Portugal, and held an ESMO Clinical Unit Visit Fellowship (Phase I and Breast Cancer Units) at Vall d'Hebron Institut d'Oncologia, Barcelona, Spain. ESMO Faculty Group for Head and Neck Cancer (2017-2021). Participation in the 13th ECCO-AARC-EORTC-ESMO Workshop "Methods in Clinical Cancer Research", Flims, Switzerland. Experience as an investigator in phase I-III clinical trials, including investigator-initiated studies. Author or co-author of about 70 publications in national and international journals. Peer-reviewer of several journals: Scientific Reports - Nature, Communications Biology, International Journal of Radiation Oncology, Frontiers, Pharmacological Research, BMJ case reports, Case Reports in Oncology, Head & Neck, World Journal of Gastroenterology, Annals of Translational Medicine, American Journal of Ophthalmology Case Reports, Diving and Hyperbaric Medicine, Acta Médica Portuguesa and Gazeta Médica. Board-certified in Medical Oncology by the Portuguese Board of Medical Oncology and in Underwater and Hyperbaric Medicine by the Portuguese Medical Association. Certified member of several societies and professional organisations (ESMO, ASCO, ESGO, Ordem dos Médicos, SPO, and CINAV). His current investigation aims to introduce microbiota/microbiome analysis as part of clinical practice to improve disease prevention and early detection, better-targeted therapy, and even microbiota manipulation to restore the organism´s homeostasis.
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Identification

Personal identification

Full name
Diogo D'agorreta D'alpuim Santos Costa

Citation names

  • Diogo Costa
  • Diogo Alpuim Costa

Author identifiers

Ciência ID
471D-3837-EEB4
ORCID iD
0000-0002-1377-3032
Google Scholar ID
https://scholar.google.com/citations?user=JmhOQCUAAAAJ&hl=pt-PT
Scopus Author Id
57204193643

Email addresses

  • diogo.costa@cuf.pt (Professional)
  • diogo.santos.costa@hospitaldecascais.pt (Professional)
  • diogoalpuimcosta@gmail.com (Personal)

Telephones

Mobile phone
  • (+351) 914523848 (Personal)

Addresses

  • Praçeta da União Recreativa e Cultural da Abrunheira, Número 6, 2710-024, Abrunheira, Sintra, Portugal (Personal)

Websites

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Medical and Health Sciences - Clinical Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Elementary (A2) Intermediate (B1) Elementary (A2) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Intermediate (B1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
Education
Degree Classification
2021 - 2024/07/08
Concluded
 Master in Hyperbaric and Underwater Medicina (Mestrado)
Universidade de Lisboa - Faculdade de Medicina, Portugal
"Validação clínica da Portuguese Navy Radiation-induced Cystitis Scale na avaliação e monitorização da cistite rádica em resposta à oxigenoterapia hiperbárica" (THESIS/DISSERTATION)
 19
2015/10 - 2023
Ongoing
 PhD student (Doutoramento)
NOVA Medical School | Faculdade de Ciências Médicas, Portugal
2021/07
Concluded
 Competence in Military Medicine (Outros)
Ordem dos Médicos, Portugal
 Approved
2019/07/31
Concluded
 Senior Officer Promotion Course - Health and Military Sector (Outros)
Instituto Universitário Militar, Portugal
 17,02
2017/08/11
Concluded
 Competence in Hyperbaric and Underwater Medicine (Outros)
Ordem dos Médicos, Portugal
 Approved
2009/01/05 - 2015/12/02
Concluded
 Medical Oncologist (Título de especialista)
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
 19,2
2014/07/01 - 2014/09/30
Concluded
 ESMO Clinical Unit Visit Fellowship (Phase I and Breast Cancer Units) (Outros)
Vall d¿Hebron Hospital Universitari, Spain
 Approved
2011/10/31
Concluded
 Sports Medicine (Pós-Graduação)
Universidade de Lisboa - Faculdade de Medicina, Portugal
 Approved
2011/09/11
Concluded
 Pain Medicine (Pós-Graduação)
Universidade de Lisboa - Faculdade de Medicina, Portugal
 18
2007/11/23
Concluded
 Military Health (Pós-Graduação)
Escola do Serviço de Saúde Militar, Portugal
 Approved
2001/10/12 - 2007/10/01
Concluded
 Complementary Military Training in Medicine (Outros)
Major in Naval Doctor
Escola Naval, Portugal
2001/09/01 - 2007/07/31
Concluded
 Medicine (Licenciatura)
Universidade de Lisboa - Faculdade de Medicina, Portugal
"Postulados para a utilização do oxigénio hiperbárico associado à radioterapia em Oncologia (Memória Final de Curso)" (THESIS/DISSERTATION)
 15,4
1986 - 2000/06/25
Concluded
 Pre-school, Grade School, Middle School, High School (Outros)
Salesianos do Estoril (Escola Técnica e Liceal Salesiana de Santo António do Estoril), Portugal
 18,2
Affiliation

Positions / Appointments

Category
Host institution 		Employer
2024/03/01 - Current Organic Unit Director CUF, Portugal
CUF, Portugal
2023/11 - Current Organic Unit Director Centro Hiperbárico de Cascais (CHC), Portugal
2023/01/10 - Current Organic Unit Director Hospital de Cascais Dr José de Almeida, Portugal
2023 - Current Medical Oncologist Instituto Medico Alto da Castelhana (IMAC), Portugal
2022 - Current Medical Oncologist Specialist and Underwater and Hyperbaric Physician AIM Cancer Center, Portugal
AIM Cancer Center, Portugal

Others

Category
Host institution 		Employer
2025/05 - Current Underwater and Hyperbaric Physician Hospital da Luz, Portugal
2016/01/03 - Current Medical Oncologist Specialist CUF, Portugal
CUF, Portugal
2007/10/01 - Current Naval Doctor Marinha Portuguesa, Portugal
2007 - Current Medical Doctor (License Number: 47185) Ordem dos Médicos, Portugal
2015/07/14 - 2023 Underwater and Hyperbaric Physician (Military Identification Number: 20401) Marinha Portuguesa - Centro de Medicina Subaquática e Hiperbárica, Portugal
2020 - 2022/07/31 Consultant Kabushiki Kaisha NTT Data, Japan
Projects

Grant

Designation Funders
2022/05/26 - Current A pilot study of gut microbiota profile characterisation of patients with different molecular subtypes of newly diagnosed breast cancer – A case-control study
BioBreast
Research Fellow
NOVA Medical School | Faculdade de Ciências Médicas, Portugal
 AstraZeneca Produtos Farmacêuticos Lda
Ongoing
2018 - Current Utilidade clínica da quantificação do ADN e da expressão do ARN mensageiro da proteína oncogénica BARF-1 do vírus de Epstein-Barr, como factores preditivos de resposta e de monitorização à terapêutica do carcinoma indiferenciado da nasofaringe - Estudo VEBiNASO
VEBINASO
Research Fellow
NOVA Medical School | Faculdade de Ciências Médicas, Portugal
 Grupo José de Mello
Ongoing

Other

Designation Funders
2025 - Current A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)
NCT06472076
Principal investigator
Ongoing
2024/07 - Current A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer (PACIFIC-9)
NCT05221840
Principal investigator
Hospital de Cascais Dr José de Almeida, Portugal
Ongoing
2024/06 - Current A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
NCT06136650
Researcher
Ongoing
2023 - Current CAMBRIA-1: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy with Camizestrant (AZD9833, a Next Generation, Oral Selective Estrogen Receptor Degrader) versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) in Patients with ER+/HER2- Early B
NCT05774951
Co-Principal Investigator (Co-PI)
Hospital CUF Descobertas, Portugal
Ongoing
2021 - Current A Phase 3 (Pivotal Stage) Study of NBTXR3 Activated by Investigator´s Choice of Radiotherapy Alone or Radiotherapy in Combination with Cetuximab for Platinum-based Chemotherapy- ineligible Elderly Patients with Locally Advanced Head & Neck Squamous Cell Carcinoma - NANORAY-312
NCT04892173
Principal investigator
Hospital CUF Descobertas, Portugal
Ongoing
2021 - Current A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study Of Trastuzumab Deruxtecan VERSUS Trastuzumab Emtansive In Subjects With High-Risk HER2-Positive Primary Breast Cancer Who Have Residual Invasive Disease In Breast/Axillary Lymph Nodes Following Neoadjuvant Therapy
NCT04622319
Researcher
Hospital CUF Descobertas, Portugal
Ongoing
2021 - Current A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Breast Cancer
NCT04711252
Researcher
Hospital CUF Descobertas, Portugal
Ongoing
2019 - Current Phase II Study of Tucatinib vs Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer (HER2CLIMB)
NCT02614794
Researcher
Hospital CUF Descobertas, Portugal
Ongoing
2019 - Current A Phase III, Randomized, Open-label Study to Evaluate Pembrolizumab as Neoadjuvant Therapy and in Combination With Standard of Care as Adjuvant Therapy for Stage III-IVA Resectable Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA HNSCC)
NCT03765918
Principal investigator
Hospital CUF Descobertas, Portugal
Ongoing
2019 - Current VIOLLETE - AstraZeneca AB, D5336C00001, A Phase II, Open Label, Randomised, Multi-Centre Study to Assess the Safety and Efficacy of Agents Targeting DNA Damage Repair in Combination with Olaparib versus Olaparib Monotherapy in the Treatment of Metastatic Triple Negative Breast Cancer
NCT03284957
Researcher
Hospital CUF Descobertas, Portugal
Ongoing
2019 - Current An Open-Label Phase 2 Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib (PUMA-NER-6203)
NCT04366713
Researcher
Hospital CUF Descobertas, Portugal
Concluded
2019 - Current An Open-Label, Phase IIIB, Single Arm, Multicenter Safety Study Of Atezolizumab (Tecentriq) Plus Nab-paclitaxel or Paclitaxel In The Treatment of Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer
NCT04148911
Researcher
Hospital CUF Descobertas, Portugal
Ongoing
2017 - Current TED14856 - SAR439859-TED14856-OF-SQ-MA - A Phase 1/2 study for the safety, efficacy, pharmacokinetic and pharmacodynamics evaluation of SAR439859, administered orally in monotherapy and in combination with palbociclib in postmenopausal women with advanced estrogen receptor positive breast cancer
NCT03284957
Researcher
Hospital CUF Descobertas, Portugal
Ongoing
2021/07 - 2022/12 Frequency of low HER2 expression in metastatic triple-negative breast cancer and its influence on outcome: a retrospective, international analysis for quality assurance coordinated by the Austrian Group Medical Tumor Therapy (AGMT)
HER2-LOW mTNBC
Principal investigator
Hospital CUF Descobertas, Portugal
Ongoing
2019 - 2020 A phase 3, randomized, blinded, placebo-controlled study of tislelizumab (BGB-A317) plus chemoradiotherapy followed by tislelizumab monotherapy in newly diagnosed, stage III subjects with locally advanced, unresectable non-small cell lung cancer
NCT03745222
Co-Principal Investigator (Co-PI)
Concluded
2018 - 2020 Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Postmenopausal Women With HR+ HER2- aBC (CompLEEment).
NCT02941926
Researcher
Hospital CUF Descobertas, Portugal
Concluded
2018 - 2019 Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer (Olympia)
NCT02032823
Researcher
Hospital CUF Descobertas, Portugal
Concluded
2015 - 2019 PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Early Breast Cancer (PALLAS)
NCT02513394
Researcher
Concluded
2013 - 2015 Open-label, multicentre study to evaluate the safety of vemurafenib in patients with metastatic melanoma
NCT01307397
Researcher
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
Concluded
2011 - 2015 Prospective Study for evaluation of efficacy, toxicity and effect on quality of life of chemotherapy based on platinum with cetuximab in advanced or metastatic tumours of the head and neck in Portuguese Oncology Institute of Lisbon – EXTREME-IPOL
EXTREME-IPOL
Researcher
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
Concluded
Outputs

Publications

Book
  1. Diogo Alpuim Costa. Receitas e conselhos para doentes oncológicos. Portugal. 2023.
    Published
Conference abstract
  1. Diogo Alpuim Costa. "Carga Viral EBV - factores preditivos de resposta e de monitorização à terapêutica do carcinoma indiferenciado da nasofaringe - Estudo VEBiNASO". Paper presented in IX Encontro da Sociedade Portuguesa de Virologia, V Congresso Nacional de Virologia, Porto, 2018.
    Published
  2. Diogo Alpuim Costa. "The role of adjuvant chemotherapy in patients with stage II/III upper-rectal cancer". Paper presented in European Cancer Congress (ECCO-ESM-ESTRO-ESSO-EACR-EONS-SIOPE), Viena, 2015.
    Published
  3. Diogo Alpuim Costa. "Hyperbaric oxygen therapy for the management of late-onset haemorrhagic cystitis after allogeneic bone marrow transplantation". Paper presented in European Cancer Congress (ECCO-ESM-ESTRO-ESSO-EACR-EONS-SIOPE), Viena, 2015.
    Published
  4. Diogo Alpuim Costa. "Venous thrombotic events in patients with glioblastoma". Paper presented in Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, 2015.
  5. Diogo Alpuim Costa. "Prevention and treatment of oral mucositis in patients treated with chemoradiotherapy with head and neck cancer". Paper presented in ICHNO 5th International Conference on Innovative Approaches in Head & Neck Oncology, Nice, 2015.
    Published
  6. Diogo Alpuim Costa. "Toxicity and feasibility of adjuvant chemotherapy in nasopharynx carcinoma: a retrospective study". Paper presented in ICHNO 5th International Conference on Innovative Approaches in Head & Neck Oncology, Nice, 2015.
    Published
  7. Diogo Alpuim Costa. "Neoadjuvant Chemotherapy (CT) with Docetaxel, Cisplatin and 5-Fluorouracil (TPF) before concomitant Chemoradiation for Locoregionally Advanced (LA) Squamous Cell Carcinomas of the Head and Neck (SCCHN): Single-center experience and results of an Intensive Nurse-Led Support Program (INSLP).". Paper presented in European Cancer Congress (ECCO-ESMO-ESTRO), Madrid, 2014.
    Published
  8. Diogo Alpuim Costa. "Sinonasal adenocarcinoma (SNA) - Experience of an Oncology Center". Paper presented in European Society for Medical Oncology (ESMO) Congress, Madrid, 2014.
    Published
  9. Diogo Alpuim Costa. "The relevance of Epstein-Barr virus (EBV) DNA load and the messenger RNA (mRNA) expression of the oncogenic protein BARF1, as response and therapeutic monitoring predictive factors in Undifferentiated nasopharyngeal carcinoma – The VEBiNASO STUDY.". Paper presented in 23rd Biennial EACR Congress, Munique, 2014.
    Published
  10. Diogo Alpuim Costa. "HIV and cancer: The 8-year experience of the reference center of infectious diseases in Portugal". Paper presented in Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, 2014.
    Published
  11. Diogo Alpuim Costa. "Cetuximab (CTX) Plus Platinum-Based Chemotherapy (CT) in Recurrent and Metastatic Head-and-Neck Squamous Cell Carcinoma (HN SCC): Our Extreme Experience". Paper presented in ASCO-ASTRO Multidisciplinary Head & Neck Cancer Symposium, Scottsdale, 2014.
    Published
  12. Diogo Alpuim Costa. "Esthesioneuroblastoma – The 15-year experience of a Cancer Institute". Paper presented in European Cancer Congress (ECCO-ESMO-ESTRO), Amesterdão, 2013.
    Published
  13. Diogo Alpuim Costa. "Cetuximab (CTX) in recurrent and metastatic Head and Neck Squamous-Cell Carcinoma (HN SCC) – our EXTREME experience". Paper presented in ICHNO 4th International Conference on Innovative Approaches in Head & Neck Oncology, Barcelona, 2013.
    Published
  14. Diogo Alpuim Costa. "Donepezil and variable atrioventricular block – A case report". Paper presented in 8th Congress of the European Federation of Internal Medicine, Istanbul, 2009.
    Published
Conference paper
  1. Diogo Alpuim Costa. "The Effectiveness of Hyperbaric Oxygen Therapy for Managing Radiation- Induced Urethral Late Complications - A Retrospective Study". Paper presented in 47th EUBS Annual Scientific Meeting, Oporto, 2023.
    Published
  2. Diogo Alpuim Costa. "The Effectiveness of Hyperbaric Oxygen Therapy for Managing Radiation- Induced Proctitis -A Retrospective Study". Paper presented in 47th EUBS Annual Scientific Meeting, Oporto, 2023.
    Published
  3. Diogo Alpuim Costa. "Late-onset haemorrhagic cystitis after allogeneic haematopoietic stem cell transplantation". Paper presented in 47th EUBS Annual Scientific Meeting, Oporto, 2023.
    Published
  4. Diogo Alpuim Costa. "The effects of hyperbaric oxygen therapy on insulin resistance - An approach to physiology". Paper presented in 47th EUBS Annual Scientific Meeting, Oporto, 2023.
    Published
  5. Diogo Alpuim Costa. "HER2-low versus HER2-0 in Invasive Lobular Breast Carcinoma". Paper presented in 13th European Breast Cancer Conference (EBCC-13), Barcelona, 2022.
    Published
  6. Diogo Alpuim Costa. "A importância da recompressão precoce na doença de descompressão". Paper presented in 38º Congresso de Pneumologia, Algarve, 2022.
    Published
  7. Diogo Alpuim Costa. "Oxigenoterapia Hiperbárica no tratamento das infeções necrotizantes da pele e tecidos moles". Paper presented in The Southside of Urology 2022, Costa da Caparica, 2022.
    Published
Conference poster
  1. Diogo Alpuim Costa. "Hyperbaric Oxygen Therapy in the treatment of necrotising infections of the skin and soft tissues". Paper presented in 47th EUBS Annual Scientific Meeting, 2023.
  2. Diogo Alpuim Costa. "Is preoperative chemosensitivity associated with improved outcomes in locally advanced gastric cancer? – A multicentric retrospective real-world study". Paper presented in World Congress on Gastrointestinal Cancer, 2023.
  3. Diogo Alpuim Costa. "A phase 2 study of magrolimab combination therapy in patients with recurrent or metastatic head and neck squamous cell carcinoma: ELEVATE HNSCC.". Paper presented in American Society of Clinical Oncology (ASCO) Annual Meeting, 2023.
  4. Diogo Alpuim Costa. "A importância da oxigenoterapia hiperbárica no tratamento da embolia gasosa". Paper presented in 38.º Congresso de Pneumologia, 2022.
  5. Diogo Alpuim Costa. "Intestinal Microbiota Profile of COVID-19 patients. Prognosis and risk stratification (MicroCOVID-19)". Paper presented in AIMS Research Competition., 2021.
  6. Diogo Alpuim Costa. "Oxigenoterapia Hiperbárica: o Limite entre o Saudável e o Cancerígeno". Paper presented in GAPIC, 2019.
  7. Diogo Alpuim Costa. "Atingindo por ar? Um caso raro de pneumocéfalo". Paper presented in XII Congresso Nacional de Medicina Intensiva / VII Congresso Luso Brasileiro de Medicina Intensiva, 2019.
  8. Diogo Alpuim Costa. "Neoplasia do pâncreas metastática com resposta completa a folfirinox em associação com hipertermia de corpo inteiro: a propósito de um caso clínico.". Paper presented in 14.º Congresso Nacional de Cancro Digestivo, 2018.
  9. Diogo Alpuim Costa. "Seizure incidence in more than 150.000 treatment sessions with hyperbaric oxygen therapy – A single centre analysis". Paper presented in 42nd Annual Scientific Meeting of the European Underwater & Baromedical Society, 2016.
  10. Diogo Alpuim Costa. "Clinical effectiveness of hyperbaric oxygen therapy for haemorrhagic cystitis after pelvic irradiation for gynaecological tumour – a case report". Paper presented in International Meeting of The European Society of Gynaecological Oncology (ESGO), 2015.
  11. Diogo Alpuim Costa. "Aparente tumor de Pancoast: a propósito de um caso clínico". Paper presented in 2º Congresso Luso-Brasileiro de Oncologia, 2015.
  12. Diogo Alpuim Costa. "Influence of screening Echocardiogram on clinical decision-making in the treatment of breast cancer with anthracycline regimens". Paper presented in Cardiac Safety Research Consortium (CSRC) and International CardiOncology Society (ICOS) Annual Conference Meeting, 2013.
  13. Diogo Alpuim Costa. "Oxigenoterapia hiperbárica na osteorradionecrose da mandíbula". Paper presented in Encontros da Primavera de Oncologia, 2013.
  14. Diogo Alpuim Costa. "Neuroblastoma do adulto jovem: a propósito de dois casos clínicos". Paper presented in Encontros da Primavera de Oncologia, 2013.
  15. Diogo Alpuim Costa. "Valproato de sódio no carcinoma indiferenciado da nasofaringe". Paper presented in Encontros da Primavera de Oncologia, 2013.
  16. Diogo Alpuim Costa. "Apresentação rara de cancro do pulmão". Paper presented in Encontros da Primavera de Oncologia, 2013.
  17. Diogo Alpuim Costa. "Pneumonite aguda induzida pelo paclitaxel : 2 casos clínicos". Paper presented in Encontros da Primavera de Oncologia, 2012.
  18. Diogo Alpuim Costa. "Arritmia maligna secundária a processo neoplásico". Paper presented in Encontros da Primavera de Oncologia, 2012.
  19. Diogo Alpuim Costa. "Terapêutica Adjuvante nas Mulheres Mais Velhas com Cancro da Mama em Estadio Precoce: Estado da Arte e Perspectivas Futuras". Paper presented in Encontros da Primavera de Oncologia, 2012.
  20. Diogo Alpuim Costa. "Uma Forma Explosiva de Metastização de Melanoma Maligno". Paper presented in Encontros de Primavera de Oncologia, 2012.
  21. Diogo Alpuim Costa. "Enterocolite Neutropénica: A Propósito de um Caso Clínico". Paper presented in Encontros da Primavera de Oncologia, 2012.
  22. Diogo Alpuim Costa. "Tumor de células germinativas bilateral do testículo – a propósito de um caso clínico". Paper presented in Encontros da Primavera de Oncologia, 2012.
  23. Diogo Alpuim Costa. "Fisiopatologia da Associação entre Neoplasias Malignas e Esclerose Sistémica: Base Molecular Comum, Coincidência ou uma Janela para a Compreensão da Relação entre Imunidade e Cancro?". Paper presented in Encontros da Primavera de Oncologia, 2012.
  24. Diogo Alpuim Costa. "Um Caso Clínico de Melanoma Avançado B-RAF +". Paper presented in Encontros da Primavera de Oncologia, 2012.
  25. Diogo Alpuim Costa. "Hipertensão Pulmonar Paraneoplásica como Forma de Apresentação de Adenocarcinomas Síncronos do Pâncreas e Cólon Direito com Padrão Bizarro de Metastização". Paper presented in Encontros da Primavera de Oncologia, 2012.
  26. Diogo Alpuim Costa. "GIST: Longa Sobrevivência após Resistência ao Imatinib". Paper presented in Encontros da Primavera de Oncologia, 2012.
  27. Diogo Alpuim Costa. "Quando o antibiótico falha". Paper presented in 17º Congresso Nacional de Medicina Interna, 2011.
Journal article
  1. Uppaluri, Ravindra; Haddad, Robert I.; Tao, Yungan; Le Tourneau, Christophe; Lee, Nancy Y.; Westra, William; Chernock, Rebecca; et al. "Neoadjuvant and Adjuvant Pembrolizumab in Locally Advanced Head and Neck Cancer". New England Journal of Medicine 393 1 (2025): 37-50. https://doi.org/10.1056/nejmoa2415434.
    10.1056/nejmoa2415434
  2. Alpuim Costa, Diogo; Barata Coelho, Pedro; Calhau, Conceição; Faria, Ana. "Editorial: Gut microbiota in health and disease". Frontiers in Gastroenterology 4 (2025): https://doi.org/10.3389/fgstr.2025.1568509.
    Published • 10.3389/fgstr.2025.1568509
  3. Vasconcelos de Matos, Leonor; Borges, Margarida; Oliveira, Ana Teresa; Bulhosa, Carolina; Miguel, Luís Silva; Fidalgo de Freitas, Tiago; Cunha, Renato; et al. "The impact on productivity costs of reducing unemployment in patients with advanced breast cancer: A model estimation based on a Portuguese nationwide observational study". The Breast 79 (2025): 103867. https://doi.org/10.1016/j.breast.2024.103867.
    Published • 10.1016/j.breast.2024.103867
  4. Arana Ribeiro, Joana; Alpuim Costa, Diogo; Gaio-Lima, Clara; Guilherme Gonçalves-Nobre, José; Portugal Rodrigues, Inês; Trigo Miranda, Mariana; Pinho Vaz, Carlos; D’Espiney Amaro, Carla; Camacho, Óscar. "Hyperbaric oxygen therapy in the treatment of late-onset hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation". Scientific Reports 14 1 (2024): https://doi.org/10.1038/s41598-024-74858-8.
    Published • 10.1038/s41598-024-74858-8
  5. Andaluz, Stephanie; Zhao, Bojin; Sinha, Siddharth; Lagniton, Philip Naderev Panuringan; Costa, Diogo Alpuim; Ding, Xiaofan; Brito, Miguel; Wang, San Ming. "Using Portuguese BRCA pathogenic variation as a model to study the impact of human admixture on human health". BMC Genomics 25 1 (2024): http://dx.doi.org/10.1186/s12864-024-10311-4.
    Published • 10.1186/s12864-024-10311-4
  6. Carrolo, Margarida; Miranda, João A. I.; Vilhais, Guilherme; Quintela, António; Sousa, Mário Fontes e; Costa, Diogo Alpuim; Pinto, Francisco R.. "Metastatic organotropism: a brief overview". Frontiers in Oncology 14 (2024): http://dx.doi.org/10.3389/fonc.2024.1358786.
    Published • 10.3389/fonc.2024.1358786
  7. Diogo Alpuim Costa; Joana Arana Ribeiro; Carla D'Espiney Amaro. "Hyperbaric Oxygen Therapy as a Complementary Treatment for Osteoradionecrosis of the Mandible: Useless or Useful? - A Literature Review". Gazeta Médica (2024): https://doi.org/10.29315/gm.v1i1.788.
    10.29315/gm.v1i1.788
  8. Vilhais, Guilherme; Alpuim Costa, Diogo; Fontes-Sousa, Mário; Ribeiro, Pedro Casal; Martinho, Filipa; Botelho de Sousa, Carolina; Santos, Catarina Rodrigues; et al. "Case report: Primary CDK4/6 inhibitor and endocrine therapy in locally advanced breast cancer and its effect on gut and intratumoral microbiota". Frontiers in Oncology 14 (2024): http://dx.doi.org/10.3389/fonc.2024.1360737.
    Published • 10.3389/fonc.2024.1360737
  9. Rodrigues Alves, Nuno; Duarte, Ana Filipa; Ribeiro, David Fernandes; Silva, Rita Sousa; Carvalho, Bruno Almeida; Alpuim Costa, Diogo. "Successful management of bilateral orbital metastases from invasive lobular breast cancer with abemaciclib and letrozole: a case report and literature review". Frontiers in Oncology 14 (2024): http://dx.doi.org/10.3389/fonc.2024.1286910.
    Published • 10.3389/fonc.2024.1286910
  10. Alpuim Costa, Diogo; Gonçalves-Nobre, J. Guilherme; Sampaio-Alves, Mafalda; Guerra, Nuno; Arana Ribeiro, Joana; Espiney Amaro, Carla. "Hyperbaric oxygen therapy as a complementary treatment in neuroblastoma - A narrative review". Frontiers in Oncology 13 (2023): http://dx.doi.org/10.3389/fonc.2023.1254322.
    Published • 10.3389/fonc.2023.1254322
  11. Vicente, Rodrigo Santos; Freitas, Ana Rita; Ferreira, Ricardo Miguel Azevedo; Prada, Sofia Parada; Martins, Telma Sofia; Martins, Telma Caleça; Duarte Mendes, Ana; et al. "Communication preferences and perceptions of cancer patient during their first medical oncology appointment". Psycho-Oncology (2023): http://dx.doi.org/10.1002/pon.6220.
    Published • 10.1002/pon.6220
  12. Gonçalves-Nobre, J. Guilherme; Gaspar, Inês; Alpuim Costa, Diogo. "Anthracyclines and trastuzumab associated cardiotoxicity: is the gut microbiota a friend or foe? - A mini-review". Frontiers in Microbiomes 2 (2023): http://dx.doi.org/10.3389/frmbi.2023.1217820.
    10.3389/frmbi.2023.1217820
  13. Moreira Monteiro, António; Alpuim Costa, Diogo; Mareco, Virgínia; Espiney Amaro, Carla. "The effectiveness of hyperbaric oxygen therapy for managing radiation-induced proctitis – results of a 10-year retrospective cohort study". Frontiers in Oncology 13 (2023): http://dx.doi.org/10.3389/fonc.2023.1235237.
    10.3389/fonc.2023.1235237
  14. Telma Caleça; Pedro Ribeiro; Marina Vitorino; Maria Menezes; Mafalda Sampaio-Alves; Ana Duarte Mendes; Rodrigo Vicente; et al. "Breast Cancer Survivors and Healthy Women: Could Gut Microbiota Make a Difference? BiotaCancerSurvivors: A Case-Control Study". Cancers (2023): https://doi.org/10.3390/cancers15030594.
    10.3390/cancers15030594
  15. Gampenrieder, S.P.; Dezentjé, V.; Lambertini, M.; de Nonneville, A.; Marhold, M.; Le Du, F.; Cortés Salgado, A.; et al. "Influence of HER2 expression on prognosis in metastatic triple-negative breast cancer—results from an international, multicenter analysis coordinated by the AGMT Study Group". ESMO Open 8 1 (2022): 100747. http://dx.doi.org/10.1016/j.esmoop.2022.100747.
    Published • 10.1016/j.esmoop.2022.100747
  16. Diogo Alpuim Costa; José Guilherme Nobre; Mariana Delgadinho; Carina Silva; Joana Mendes; Vanessa Mateus; Edna Ribeiro; et al. "Gut microbiota profile of COVID-19 patients: Prognosis and risk stratification (MicroCOVID-19 study)". Frontiers in Microbiology 13 (2022): http://dx.doi.org/10.3389/fmicb.2022.1035422.
    10.3389/fmicb.2022.1035422
  17. Diogo Alpuim Costa; José Guilherme Nobre; D. Alpuim Costa. "”Sociobiome”: How do socioeconomic factors influence gut microbiota and enhance pathology susceptibility? - A mini-review". Frontiers in Gastroenterology 1 (2022): http://dx.doi.org/10.3389/fgstr.2022.1020190.
    10.3389/fgstr.2022.1020190
  18. Rodrigo Vicente; Diogo Alpuim Costa; Marina Vitorino; Ana Duarte Mendes; Catarina Santos; Mário Fontes-Sousa. "Mutation Patterns in Portuguese Families with Hereditary Breast and Ovarian Cancer Syndrome". Cancers (2022): https://doi.org/10.3390/cancers14194717.
    10.3390/cancers14194717
  19. Marta Filipa Freire Vaz Batista; Inês Eiriz; Amanda Fitzpatrick; Fanny Le Du; Sofia Braga; Diogo Alpuim Costa. "Refining therapy in patients with HER2-positive Breast cancer with Central Nervous System metastasis". Breast Care (2022): https://doi.org/10.1159/000526431.
    10.1159/000526431
  20. Marina Vitorino; Diogo Alpuim Costa; Rodrigo Vicente; Telma Caleça; Catarina Santos. "Local Breast Microbiota: A “New” Player on the Block". Cancers (2022): https://doi.org/10.3390/cancers14153811.
    10.3390/cancers14153811
  21. Alpuim Costa, Diogo; Sampaio-Alves, Mafalda; Netto, Eduardo; Fernandez, Gonçalo; Oliveira, Edson; Teixeira, Andreia; Daniel, Pedro Modas; Bernardo, Guilherme Silva; Amaro, Carla. "Hyperbaric Oxygen Therapy as a Complementary Treatment in Glioblastoma - A Scoping Review". Frontiers in Neurology 13 (2022): http://dx.doi.org/10.3389/fneur.2022.886603.
    Accepted • 10.3389/fneur.2022.886603
  22. Alpuim Costa, Diogo; Nobre, José Guilherme Gonçalves; Fernandes, João Paulo; Batista, Marta Vaz; Simas, Ana; Sales, Carolina; Gouveia, Helena; et al. "Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal: A Cross-Sectional Survey-Based Study of Medical Oncologists". Oncology and Therapy (2022): http://dx.doi.org/10.1007/s40487-022-00191-7.
    Published • 10.1007/s40487-022-00191-7
  23. Vitorino, Marina; Baptista de Almeida, Susana; Alpuim Costa, Diogo; Faria, Ana; Calhau, Conceição; Azambuja Braga, Sofia. "Human Microbiota and Immunotherapy in Breast Cancer - A Review of Recent Developments". Frontiers in Oncology 11 (2022): http://dx.doi.org/10.3389/fonc.2021.815772.
    10.3389/fonc.2021.815772
  24. Marta Vaz Batista; Diogo Alpuim Costa; Paula Borralho; Sofia Braga. "Next-Generation Sequencing in Breast Cancer Management: A Case Report of Genomic Tumour Evolution over Time". Case Reports in Oncology (2021): https://doi.org/10.1159/000517441.
    10.1159/000517441
  25. Diogo Alpuim Costa. "Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? - A literature review". World Journal of Gastroenterology (2021): https://www.wjgnet.com/1007-9327/full/v27/i27/4413.htm.
    Open access • Published
  26. Diogo Alpuim Costa. "Adenoid cystic carcinoma of the palpebral lobe of the lacrimal gland – case report and literature review". Orbit (2021): https://www.tandfonline.com/doi/abs/10.1080/01676830.2021.1901293.
    Published
  27. Alpuim Costa D; Modas Daniel P; Vieira Branco J. "The Role of Hyperbaric Oxygen Therapy in Pneumatosis Cystoides Intestinalis-A Scoping Review.". Frontiers in medicine (2021): http://europepmc.org/abstract/med/33681242.
    10.3389/fmed.2021.601872
  28. Costa, Diogo Alpuim; Nobre, José Guilherme; Batista, Marta Vaz; Ribeiro, Catarina; Calle, Catarina; Cortes, Alfonso; Marhold, Maximilian; et al. "Human microbiota and breast cancer: is there any relevant link? A literature review and new horizons toward personalised medicine". (2021): http://hdl.handle.net/10400.21/12964.
    10.3389/fmicb.2021.584332
  29. Alpuim Costa D; Monteiro A; André T; Esteves S; Sargento I; Ferreira M; Alexandre T; et al. "A Potential Link Between Prolonged Cork Exposure and Intestinal-Type Sinonasal Adenocarcinoma - Special Findings of a Retrospective Cohort Analysis.". Frontiers in oncology (2020): http://europepmc.org/abstract/med/33072596.
    10.3389/fonc.2020.565036
  30. Rodrigo Santos Vicente; Diogo Alpuim Costa; Miguel Castelo Branco. "Oxigenoterapia Hiperbárica Enquanto Terapêutica Complementar da Úlcera do Pé Diabético: Útil ou Inútil? – Uma Revisão da Literatura". Gazeta Médica (2020): https://doi.org/10.29315/gm.v7i1.308.
    10.29315/gm.v7i1.308
  31. Alpuim Costa, Diogo; Gonçalves Nobre, José Guilherme; de Almeida, Susana Baptista; Ferreira, Marisa Horta; Gonçalves, Inês; Braga, Sofia; Pais, Diogo. "Cancer during pregnancy : how to handle the bioethical dilemmas? : a scoping review with paradigmatic cases-based analysis". (2020): http://hdl.handle.net/10451/46275.
    10.3389/fonc.2020.598508
  32. Figueira PJ; Alpuim Costa D; Barbagallo N; Guerreiro FG. "Stage III Kienböck's disease treated with hyperbaric oxygen: the role of an unusual approach to a rare condition.". BMJ case reports (2018): http://europepmc.org/abstract/med/30317203.
    10.1136/bcr-2018-226090
  33. Barata, Pedro Coelho; Costa, Diogo Alpuim; Passos Coelho, José Luís; Da Luz, Ricardo. "The Costly War Against Cancer Treatment: The Example of Metastatic Renal Cell Carcinoma in Portugal". (2018): https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/9969.
    10.20344/amp.9969
  34. Alpuim Costa D; Baptista de Almeida S; Coelho Barata P; Quintela A; Cabral P; Afonso A; Maia Silva J. "Pazopanib-Induced Cutaneous Leukocytoclastic Vasculitis: An Exclusion Diagnosis of a Multidisciplinary Approach.". Case reports in oncology (2017): http://europepmc.org/abstract/med/29387004.
    10.1159/000484402
  35. Costa DA; Barata P; Gouveia E; Mafra M. "Right cardiac intracavitary metastases from a primary intracranial myxofibrosarcoma.". BMJ case reports (2016): http://europepmc.org/abstract/med/27013654.
    10.1136/bcr-2015-214052
  36. Costa, Diogo Alpuim; Costa, Tiago Porfírio; Netto, Eduardo Carlinhos; Joaquim, Natércia; Ventura, Isabel; Pratas, Ana Cristina; Winckler, Patricia; et al. "New perspectives on the conservative management of osteoradionecrosis of the mandible: A literature review". (2016): http://hdl.handle.net/10400.1/9222.
    10.1002/hed.24495
  37. Diogo Alpuim Costa. "A spiderweb in the heart". Revista Portuguesa de Cardiologia 33 4 (2014): 255-257. https://www.revportcardiol.org/en-pdf-S2174204914000877.
    Open access • Published
Magazine article
  1. Diogo Alpuim Costa. "Sim, a cura pode estar no cocó", Sábado, 2023, https://www.sabado.pt/ciencia---saude/detalhe/sim-a-cura-pode-estar-no-coco.
  2. Diogo Alpuim Costa. "Alimentos que salvam vidas", Sábado, 2023
  3. Diogo Alpuim Costa. "Cancro da mama não é igual para todos. Eis as diferenças e riscos", Notícias ao minuto, 2022, https://www.noticiasaominuto.com/lifestyle/2118207/cancro-da-mama-nao-e-igual-para-todos-eis-as-diferencas-e-riscos.
  4. Diogo Alpuim Costa. "Graviola é 10 mil vezes mais eficaz do que a quimioterapia?", SAPO, 2022, https://viral.sapo.pt/factos/graviola-e-mais-eficaz-do-que-a-quimioterapia/.
  5. Diogo Alpuim Costa. "Avanços recentes (e determinantes) no tratamento do cancro", Revista Saúde e Bem Estar, 2022, https://saudebemestar.com.pt/avancos-recentes-e-determinantes-no-tratamento-do-cancro/.
  6. Diogo Alpuim Costa. "Cancro da cabeça e pescoço: 3 principais fatores de risco", CascaisAlgés, 2021, https://issuu.com/cascaisalges/docs/edi_o_de_agosto?fbclid=IwAR0pdc24EJxcc0bDsMgK1aeTgde5yD-TIHNszJPdo-0hpAS1CoUTmiquStI.
  7. Diogo Alpuim Costa. "Quais os fatores de risco para o cancro da cabeça e pescoço menos conhecidos?", Médio Tejo, 2021, https://mediotejo.net/consultorio-fatores-de-risco-menos-conhecidos-para-o-cancro-da-cabeca-e-pescoco/.
  8. Diogo Alpuim Costa. "Cancro da cavidade oral: Como realizar o autoexame da boca? 8 passos", Notícias ao Minuto, 2020, https://www.noticiasaominuto.com/lifestyle/1551094/cancro-da-cavidade-oral-como-realizar-a-autoexame-da-boca-8-passos.
  9. Diogo Alpuim Costa. "Estudo português associa exposição prolongada ao pó da cortiça ao aparecimento de cancro", SAPO24, 2020, https://24.sapo.pt/atualidade/artigos/exposicao-prolongada-ao-po-da-cortica-pode-levar-ao-aparecimento-de-cancro.
Newspaper article
  1. Diogo Alpuim Costa. "Dia mundial sem tabaco. Cancro do pulmão e tabaco, uma realidade indissociável potencialmente evitável", "O Mirante", 2021, https://omirante.pt/sociedade/2021-05-31-Dia-mundial-sem-tabaco.-Cancro-do-pulmao-e-tabaco-uma-realidade-indissociavel-potencialmente-evitavel-e525ea30.
  2. Diogo Alpuim Costa. "Cancro da Mama em tempos de pandemia", O MIRANTE, 2021, Saúde, https://omirante.pt/saude/2021-02-04-Cancro-da-Mama-em-tempos-de-pandemia.
  3. Diogo Alpuim Costa. "Cinco grandes inovações em cancro da mama", Público, 2020, https://www.publico.pt/2020/10/30/impar/opiniao/cinco-inovacoes-cancro-mama-1936469.

Other

Software
  1. Diogo Alpuim Costa. "ICH GOOD CLINICAL PRACTICE". E6 (R2). Transcelerate Biopharma Inc. 2023.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/06/07 What is new? The microbiome in immunotherapy Non-Melanoma Skin Cancer Symposium
Champalimaud Foundation (Lisbon, Portugal)
2024/05/25 O papel do microbioma no cancro da mama Tertúlias da Unidade de Radioterapia do SAMS - O Cancro da Mama
Clínica SAMS de Oncologia e Radioterapia (Lisboa, Portugal)
2024/04/13 Vitamina D e o cancro 5º Encontro da Vitamina D
FAES FARMA (Unhais da Serra, Portugal)
2024/03/26 Medicina Hiperbárica. O que é? Para que serve? Manhãs da Oncologia
Hospital CUF Descobertas (Lisbon, Portugal)
2024/03/21 Microbiota: Cornerstone of gastrointestinal dysfunction, immunity, and immune (hyper)activity Católica Medical Seminars
Catolica Medical School (Oeiras, Portugal)
2024/03/16 Qual a relação entre o microbioma e o cancro da pele 1º Encontro Dermato-Oncologia do Algarve
Grupo HPA Saúde (Faro, Portugal)
2024/03/01 Metastatic Renal Cancer Carcinoma - Combined treatment a good option XXIX Workshop Urologia Oncológica
Grupo Português Génito-Urinário (Lisbon, Portugal)
2024/02/20 O papel do microbioma no cancro da mama Sessão Clínica - Hospital CUF Descobertas
Hospital CUF Descobertas (Lisbon, Portugal)
2024/02/16 Perspetivas atual e futura - Algoritmo terapêutico do cancro da cabeça e pescoço metastático XII Perspectivas em Oncologia
Hospital de São João (Oporto, Portugal)
2023/11/30 Microbiota e o cancro: qual a associação? Sessão Clínica de Oncologia
Serviço de Oncologia Médica, Instituto Português de Oncologia de Lisboa Francisco Gentil (Lisbon, Portugal)
2023/11/22 Indicações terapêuticas em Câmara Hiperbárica 20 º Congresso Nacional de Oncologia
Sociedade Portuguesa de Oncologia (SPO) (Estoril, Portugal)
2023/11/10 Discussão de casos clínicos em contexto de grupo multidisciplinar Cancro de Cabeça e Pescoço num dia
Grupo de Estudos do Cancro da Cabeça e Pescoço (Lisbon, Portugal)
2023/11/04 Microbioma e o cancro: uma interação bidirecional N2S Conference
NOVA Medical School (Lisbon, Portugal)
2023/10/30 Equipa Multidisciplinar do Hospital de Dia Médico Outubro Rosa
Hospital de Cascais Dr. José de Almeida (Cascais, Portugal)
2023/09/25 Formação em Cancro da Mama Avançado
NOVARTIS (Monte Real, Portugal)
2023/05/12 Microbioma e personalização da terapêutica - O exemplo de cancro da mama 13ª reunião de Oncologia da APFH
Associação Portuguesa de Farmacêuticos Hospitalares (Peniche, Portugal)
2023/04/15 Composição corporal, sarcopenia e obesidade no cancro da mama feminino - Microbiota e cancro da mama XXV Congresso APNEP 2023
Associação Portuguesa de Nutrição Entérica e Parentérica (APNEP) (Oporto, Portugal)
2023/03/31 Terapêutica do cancro da mama - Evolução da terapêutica médica Primeiras Jornadas de Patologia Mamária da CUF Sintra/Cascais
CUF Academic Center (Sintra, Portugal)
2023/03/16 Microbiota and faecal transplantation Gut Power
Católica Medical School - Universidade Católica Portuguesa (Oeiras, Portugal)
2023/03/04 Cuidar de Dentro para Fora - Pele e microbioma (da pele e intestinal) OncoSkin
AIM Cancer Center (Lisbon, Portugal)
2023/02/18 Medicina Hiperbárica e Fertilidade - Oxigenoterapia Hiperbárica (O que é? Para que serve?) 2º Congresso do Cancro da Mama do Algarve
(Lagos, Portugal)
2022/10/21 Tratamento das metástases cerebrais - Apresentação de novas guidelines III Simpósio - Treating the brain as a vital organ
CUF Academic Center - Centro Gamma Knife (Lisbon, Portugal)
2022/05/27 Biópsias líquidas em terceira linha - Uma janela de oportunidade no cancro colorretal metastático 15ª Conferência Nacional de Enfermagem Oncológica
Associação de Enfermagem Oncológica Portuguesa (AEOP) (Olhão, Portugal)
2022/05/19 Microbiota e o Cancro Pré-graduação da Licenciatura em Ciências da Nutrição e do Mestrado Integrado em Medicina
Nova Medical School (Lisbon, Portugal)
2021/10/29 Ki67 - Como utilizar clinicamente XI Congresso Nacional de Senologia
Portuguese Society of Senology (Oporto, Portugal)
2021/10/16 Abordagem terapêutica agnóstica em Oncologia Pharma Learning Session ROCHE
Associação Portuguesa de Farmacêuticos Hospitalares (APFH) (Portugal)
2021/09/25 Outras Novidades da ASCO 2021 11º Simpósio cancro da cabeça e do pescoço
Grupo de Estudos de Cancro da Cabeça e Pescoço (Monte Real, Portugal)
2021/06/29 Câmara Hiperbárica - Está aqui mesmo ao lado! Jornadas de Endocrinologia do Hospital das Forças Armadas (HFAR)
Endocrinology Department, Hospital das Forças Armadas (HFAR) (Oeiras, Portugal)
2021/05/22 NANORAY-312 Reunião Interna da Unidade de Cancro de Cabeça e Pescoço da CUF Oncologia
CUF Descobertas Hospital (Lisbon, Portugal)
2021/05/15 Impacto do microbioma no tratamento com imunoterapia II Encontro Melanoma e Tumores Cutâneos Não Melanoma
Hospital do Espírito Santo de Évora (HEJE) (Évora, Portugal)
2021/03/20 Under pressure: Hyperbaric Medicine. AIMS meeting Annual International (bio)Medical Students Meeting (AIMS) 2021
Annual International (bio)Medical Students Meeting (AIMS) (Virtual Meeting, Portugal)
2021/03/11 Impacto da COVID-19 no cancro da mama em Portugal | Estudo Nacional Breast Cancer Session
Pfizer (Virtual Meeting, Portugal)
2020/11/09 A potential link between prolonged cork exposure and intestinal-type sinonasal adenocarcinoma – Special findings of a retrospective cohort analysis
Grupo de Trabalho da Prevenção - Sociedade Portuguesa de Oncologia (Virtual, Portugal)
2020/10/30 Convulsões hiperóxicas - Experiência do CMSH Sessão Clínica de Medicina Hiperbárica e Subaquática
Centro de Medicina Subaquática e Hiperbárica (CMSH) (Lisboa, Portugal)
2019/11/18 Medicina Hiperbárica. O que é? Para que serve? 2º Curso de Atualização em Medicina Interna (CAMI)
Sociedade Portuguesa de Medicina Interna (SPMI) (Vila do Conde, Portugal)
2019/09/21 Prime time do PD-L1 9º Simpósio Cancro da Cabeça e Pescoço
Grupo de Estudos Cancro de Cabeça e Pescoço (GECCP) (Figueira da Foz, Portugal)
2019/04/12 Perfil genómico tumoral Simpósio
ROCHE (Évora, Portugal)
2018/11/15 Oxigenoterapia hiperbárica na cistite hemorrágica tardia após transplante alogénico de medula óssea XVIII Encontro Militar da Saúde Militar CPLP
Fundação Champalimaud (Lisboa, Portugal)
2018/06/07 Portuguese experience with Comprehensive Genomic Profiling. 10th Edition Personalised Heatlhcare in Oncology
ROCHE (Amadora, Portugal)
2018/05/11 Imunoterapia: passado, presente e futuro. Advances in Head and Neck Cancer
MERCK (Lisboa, Portugal)
2018/05/11 Cancro da mama: porque morrem as nossas mulheres? X Jornadas da Primavera da CUF Cascais Hospital
CUF (Cascais, Portugal)
2018/01/26 Cancro da mama triplo negativo: terapêutica paliativa de manutenção Breast Cancer Weekend
Sociedade Portuguesa de Senologia (Porto, Portugal)
2017/11/10 Case presentation: BRAF-mutant advanced melanoma Conferências CUF 2017
CUF (Porto e Lisboa, Portugal)
2017/11/10 Utilidade clínica da quantificação do DNA, da expressão do RNA mensageiro da proteína oncogénica BARF-1 e de um painel de microRNAs enquanto biomarcadores de diagnóstico e de resposta ao tratamento do carcinoma indiferenciado da nasofaringe – Estudo VEBiNASO Sessão Clínica de Cabeça e Pescoço
Instituto Português de Oncologia do Porto Francisco Gentil, E.P.E. (IPOP) (Porto, Portugal)
2017/10/26 Toxicidade da Imunoterapia: novo desafio de um tratamento inovador Sessão Clínica de Oncologia
CUF Cascais Hospital (Cascais, Portugal)
2017/09/29 Caso clínico de cancro colorrectal metastizado GICD Academy, Bootcamp – Curso para Internos
Grupo de Investigação do Cancro Digestivo (GICD) (Figueira da Foz, Portugal)
2017/09/28 O percurso interno do doente com patologia oncológica gastrointestinal Referenciação interna do doente com cancro gastrointestinal
CUF Cascais Hospital (Cascais, Portugal)
2017/06/20 Oncovirologia Apresentação da Unidade de Diagnóstico e Tratamento de Cancro da Cabeça e Pescoço
CUF Oncologia (Lisboa, Portugal)
2017/01/05 Cancro de primário desconhecido – um diagnóstico de exclusão. Sessão Clínica de Oncologia
CUF Cascais Hospital (Cascais, Portugal)
2016/11/05 Cancro e genética: hereditariedade ou ambiente? Reunião Clínica de Oncologia
CUF (Cascais, Portugal)
2016/11/05 Tumores tratados há mais de 5 anos: vigilância versus cura Reunião Clínica de Oncologia
CUF (Cascais, Portugal)
2016/05/11 MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer Journal Club
NOVA Medical School | Faculdade de Ciências Médicas (Lisboa, Portugal)
2016/05/09 Ethmoid Sinus Tumor Journal Club
NOVA Medical School | Faculdade de Ciências Médicas (Lisboa, Portugal)
2016/05/02 Carcinoma da Nasofaringe: qual terapêutica? Sessão Clínica de Otorrinolaringologia
CUF Descobertas Hospital (Lisboa, Portugal)
2015/02/03 Intestinal-type Sinonasal Adenocarcinoma - A clinical case 14th ESO-ESMO Masterclass in Clinical Oncology
European School of Oncology (ESO) - European Society of Medical Oncology (ESMO) (Ermatingen, Switzerland)
2014/11 QRT com Cisplatina após QT Neoadjuvante com TPF em Tumores Locorregionalmente Avançados da Cabeça e Pescoço 13º Congresso Nacional de Oncologia. Porto, Portugal
Sociedade Portuguesa de Oncologia (Porto, Portugal)
2014/03/28 VIH e Cancro: A experiência de um centro de referência em doenças infecciosas. Encontros da Primavera
(Évora, Portugal)
2013/10/23 Neuroendocrine tumors: A comprehensive review. 43èmes Journées Medico-Chirurgicales
École Nationale de Sante Militaire (Algiers, Algeria)
2012/12/12 Neoplasias no doente VIH: Uma nova realidade? XI Congresso Nacional de Doenças Infecciosas e Microbiologia Clínica & IX Congresso Nacional sobre Sida
(Porto, Portugal)
2011/08/24 10 years of Hyperbaric Oxygen Therapy in the Hyperbaric and Subaquatic Medicine Centre of the Portuguese Navy Military Hospital – A single Centre Analysis. Annual Meeting of the European Underwater & Baromedical Society
European Underwater & Baromedical Society (Gdansk, Poland)
2010/05/07 Incidência de barotrauma otítico na oxigenoterapia hiperbárica. 57º Congresso Nacional da Sociedade Portuguesa de Otorrinolaringologia e Cirurgia Cervico-Facial
Sociedade Portuguesa de Otorrinolaringologia e Cirurgia Cervico-Facial (Cascais, Portugal)
2007/09/12 Postulados para a utilização do oxigénio hiperbárico associado à radioterapia em oncologia Memória Final de Curso
Escola Naval (Almada, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019 - Current Frequência de convulsões hiperóxidas em mais de 150.000 sessões de oxigenoterapia hiperbárica : a experiência de um centro de medicina subaquática e hiperbárica
Supervisor of José Rui dos Santos Ganilha
 Mestrado em Medicina Hiperbárica e Subaquática (Master)
Universidade de Lisboa - Faculdade de Medicina, Portugal
2022 - 2023 The effectiveness of hyperbaric oxygen therapy for radiation-induced proctitis – a retrospective study
Co-supervisor
 Master (Master)
Faculdade de Medicina da Universidade de Lisboa (FMUL), Portugal
2022 - 2023 Evaluation of mental health, cognitive function and quality of life of breast cancer patients and the link with gut microbiota: a preliminary study (“BioBreast Brain Study”)
Co-supervisor
NOVA Medical School¦Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Portugal
2022 - 2023 The link between breast cancer treatment toxicity and gut microbiota: a preliminary study
Co-supervisor
NOVA Medical School¦Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Portugal
2020 - 2021 O Exercício Físico, Seus Efeitos Terapêuticos e Fatores de Adesão
Co-supervisor
 Mestrado (Master)
Universidade de Lisboa Faculdade de Psicologia, Portugal
2016/03/01 - 2017/06/09 A oxigenoterapia hiperbárica enquanto terapêutica complementar do pé diabético: útil ou inútil?
Supervisor of Rodrigo dos Santos Vicente
 Mestrado Integrado em Medicina (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2013/06 - Current 13th ECCO-AARC-EORTC-ESMO Workshop "Methods in Clinical Cancer Research"
Workshop
 ECCO-AARC-EORTC-ESMO
2024/07/10 - 2024/07/12 Preceptorship on Breast Cancer - Italy
Workshop
 Preceptorship on Breast Cancer 2024
Istituto Oncologico Veneto IRCCS, Italy
2020 - 2021 Breast Cancer Masterclass - Portugal
Workshop
 Breast Cancer Preceptorship Portugal
Fundação Champalimaud, Portugal

Association member

Society Organization name Role
2015 - Current European Society of Gynaecological Oncology (ESGO) International Reviewer
2015 - Current Portuguese Society of Oncology (SPO) Member [681]
2014 - Current Centro de Investigação Naval (CINAV) Member
2013 - Current American Society of Clinical Oncology (ASCO) Member [588912]
2013 - Current International CardiOncology Society (ICOS) Member
2011 - Current European Society for Medical Oncology (ESMO) Member [264560]
2007 - Current Portuguese Medical Association Member [47185]

Committee member

Activity description
Role 		Institution / Organization
2022 - Current Frontiers in Gastroenterology - Topic Editor (Gut Microbiota in Health and Disease) Frontiers in Gastroenterology, Switzerland
2022 - Current INFUSE Steering Committee
Advisor / Consultant
2020 - Current Grupo de Estudos de Cancro da Cabeça e Pescoço
Member
 Grupo de Estudos de Cancro da Cabeça e Pescoço, Portugal
2017/01/01 - 2021/12/31 ESMO Faculty Group for Head and Neck Cancer
Member
 European Society for Medical Oncology, Switzerland

Consulting

Activity description Institution / Organization
2020/10/01 - Current Oncology Consultant Kabushiki Kaisha NTT Data, Japan
2016 - Current ESGO Guidelines for the Management of Vulvar Cancer
2008 - 2010 Medical Services ITclinical, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/12/16 - Current Cancro da mama Pós-Graduação em Enfermagem Oncológica - 2ª Edição (Pós-Graduação) Advanced Health Education (AHED), Portugal
2022/05/21 - Current Tratamentos oncológicos - quimioterapia e hormonoterapia (Pós-Graduação) NOVA Medical School | Faculdade de Ciências Médicas, Portugal
2021/09/18 - Current Ómicas, microbiota e cancro da mama Mestrado em Nutrição Humana e Metabolismo Universidade Nova de Lisboa, Portugal
2021 - Current Medical Oncology Final Exam Preparation Course (Outros) Dioscope, Portugal
2021 - Current Head and neck cancer, tissue-agnostic therapies, unknown primary cancer (Outros) Dioscope, Portugal
2024/02/19 - 2024/02/22 Microbioma em Oncologia Medicina Hiperbárica em Oncologia (Outros) AIM Cancer Center, Portugal
2024/01/27 - 2024/01/27 Microbioma & Cancro - A ligação com a Nutrição Mestrado em Nutrição Clínica (Mestrado) Faculdade de Medicina da Universidade de Lisboa (FMUL), Portugal
2020/07/07 - 2020/07/07 Head and Neck Cancer Mestrado em Investigação Biomédica (Mestrado) Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
2020/07/07 - 2020/07/07 Genomic Profile of Cancer Mestrado em Investigação Biomédica (Mestrado) Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
2020/07/07 - 2020/07/07 Microbiota / Microbiome Mestrado em Investigação Biomédica (Mestrado) Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
2019/03/09 - 2019/03/09 Avaliação das toxicidades medicamentosas. Papel do enfermeiro no hospital de dia de oncologia em cancro da cabeça e pescoço. O que nos preocupa? O que fazer? Como resolver Curso Teórico-Prático de Cancro da Cabeça e Pescoço. (Outros)
2017/05/26 - 2017/05/26 Oxigénio hiperbárico em Oncologia Mestrado em Medicina Subaquática e Hiperbárica (Mestrado) Universidade de Lisboa - Faculdade de Medicina, Portugal
2016/10/14 - 2016/10/14 Cancro colorrectal: do diagnóstico ao tratamento Curso de Formação em Enfermagem Oncológica (Outros) CUF, Portugal
2016/10/14 - 2016/10/14 Cancro de Cabeça e Pescoço: do diagnóstico ao tratamento Curso de Formação em Enfermagem Oncológica (Outros) CUF, Portugal
2016/05/19 - 2016/05/19 Head and Neck cancer Master in Oncobiology (Mestrado) Universidade do Algarve, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2022/06/09 Mudança do paradigma do tratamento do cancro da mama HER2-low com trastuzumab deruxtecano MyOncologia
2022/04/20 O que pode uma Oncologia personalizada oferecer aos doentes NTRK positivos? MyOncologia
2021/02/04 Cancro da Mama: conheça os fatores de risco que podem estar associados à doença Mood
2020/05/09 Era a viagem de uma vida e foi cancelada. Como a tripulação do Navio Sagres geriu a pandemia em alto-mar e também o regresso a casa SAPO 24
2016/11/05 Vai uma injeção de oxigénio? Sábado

Interview (tv / radio show)

Program Topic
2022 - Current Linha da Frente Dose de Contágio
2021/10/14 - Current Medicopatias Medical Oncology Internship
2020/01/16 - Current RTP - Diário de Bordo Navio-escola Sagres. Diário de Bordo
2019/10/15 - Current Diário da Manhã Qual a ligação entre o cancro da mama e o microbioma?

Journal scientific committee

Journal title (ISSN) Publisher
2023 - Current Gut Microbes
2022 - Current Annals of Translational Medicine
2022 - Current Breast Cancer: Basic and Clinical Research
2021/05 - Current Case Reports in Oncology Karger
2021/04/05 - Current Scientific Reports - Nature Springer
2021/03/25 - Current World Journal of Gastroenterology
2021 - Current Frontiers in Oncology
2021 - Current Pharmacological Research Elsevier
2021 - Current Communications Biology - Nature Springer
2021 - Current American Journal of Ophthalmology Case Reports Elsevier
2020/07/25 - Current Diving and Hyperbaric Medicine
2018/05/28 - Current Gazeta Médica Cuf Academic Center
2017/05/11 - Current Head & Neck
2016/03/03 - Current British Medical Journal Case Reports
2015/04/17 - Current Acta Médica Portuguesa

Other jury / evaluation

Activity description Institution / Organization
2021/11/18 - 2021/11/18 Jury for oral communications and posters related to head and neck cancer at the 18th Congress of the Portuguese Society of Oncology (SPO) Sociedade Portugesa de Oncologia, Portugal
2021/09/25 - 2021/09/25 Jury for oral communications and posters at the 11th Symposium of the Portuguese Head and Neck Cancer Study Group (GECCP) Grupo de Estudos de Cancro da Cabeça e Pescoço, Portugal

Scientific expedition

Activity description Institution / Organization
2023/03/09 - 2023/03/09 Round Table Moderator - Artificial Intelligence in Head and Neck cancer diagnosis and treatment European Head & Neck Society, Belgium
Distinctions

Award

2023 Medal of Military Merit
Marinha Portuguesa, Portugal
2022 Award for Best Oral Communication
Hospital Garcia de Orta EPE, Portugal
2019 Prize for the best student of the Senior Officer Promotion Course - Health and Military Sector
Instituto Universitário Militar, Portugal
2018 Research Grant
CUF, Portugal
2018 StartUp IAPMEI Voucher 2018 Portugal
Agência para a Competitividade e Inovação (IAPMEI), Portugal
2018 ENDEAVOUR-Breast 3-year Programme
Daiichi Sankyo Oncology Europe , Germany
2015 Award for Best Oral Communication
Universidade de Lisboa - Faculdade de Medicina, Portugal
2013 Award for Best Oral Communication
École Nationale de Sante Militaire, Algeria

Title

2021 Honor for Services to the Portuguese Navy
Marinha Portuguesa - Centro de Medicina Subaquática e Hiperbárica, Portugal
2020 Honor for Services to the Portuguese Navy
Marinha Portuguesa - Centro de Medicina Subaquática e Hiperbárica, Portugal
2020 Honor for Services to the Portuguese Navy
NRP Sagres, Portugal

Other distinction

2023 Former Combatant Card (Cartão de Antigo Combatente)
Portuguese State, Portugal