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Patrícia Pereira graduated in Biochemistry in 2009 by University of Beira Interior (UBI, Portugal), and completed her MSc in Biochemistry in 2011 (UBI), wherein she carried out research at Health Sciences Research Centre (CICS-UBI). In 2012, Patrícia was granted with a PhD fellowship from FCT (SFRH/BD/81914/2011), and by the beginning of 2016 she completed her PhD in Biochemistry by CICS-UBI, marked as Excellent. During her PhD, Patrícia developed and implemented new methodologies/approaches for the manufacturing, purification and delivery of microRNA-based therapeutics to Alzheimer¿s disease therapy. From June 2016 to August 2019, Patrícia was hired as post-doctoral researcher at Instituto de Tecnologia Química e Biológica António Xavier, University Nova de Lisboa (ITQB-NOVA, Portugal), integrated in the Control of Gene Expression laboratory led by Doctor Cecília Arraiano. Patrícia investigated the mechanism of action and the function of fission yeast DIS3L2 mutant proteins over different RNA substrates and she also studies the impact of the structure and function of the Ribonuclease R in Streptococcus pneumoniae. Within the framework of the post-doc work, Patrícia had a short stay at Ana Eulálio's lab (Biocant, Portugal), an expert researcher on the interplay between host cell microRNAs and bacterial infections. In 2019, Patrícia started her second postdoctoral fellowship, working at Jorge Coelho's Lab (PolySyc group, CEMPPRE, UC), where she gained experience in the synthesis and characterization of customized polymers, acquiring knowledge in a new area of research. Since 2021, Patrícia is a doctorate researcher at IPN and a member of the Integrated Doctorate of CEMMPRE. Aiming to expand her scientific knowledge, Patrícia has attended some hands-on-courses in distinct areas such as CCAIXIZ/4 | Tech Transfer Leadership in Life Sciences Course (CaixaForum Barcelona, 2022), Royce Training "3D Bioprinting for Healthcare Applications" (Manchester, 2022), NMR-From Theory to Practice (UBI, 2012), Fluorescence Microscopy and Image Analysis (UBI, 2013), Good Manufacturing Practices (UBI, 2018), and Science Communication Course (ITQB, 2018). Up to now, Patrícia (co)authored 50 scientific articles in international peer-reviewed journals in the fields of sustainable chemistry and (applied) biotechnology, 1 book chapter, 2 cover pages, 1 invited magazine-article and 2 patents (Granted: PT 110626 A; Filled: WO/2019/175849 A1). Patrícia is the first author in 19 of the 50 scientific articles, has over 720 citations, and an h-index of 17. In addition to the co-supervision of 6 MSc theses, Patrícia has also contributed in the orientation of the lab rotations of other 6 MSc students. She also participated as jury (main examiner) in 3 MSc and 5 BSc theses and teaching activities of undergraduate and graduate students.
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Identification

Personal identification

Full name
Patrícia Alexandra Nunes Pereira

Citation names

  • Pereira, Patrícia
  • Pereira, P.

Author identifiers

Ciência ID
4715-067B-4FD0
ORCID iD
0000-0002-5665-5271
Scopus Author Id
56111844900

Email addresses

  • papereira@ipn.pt (Professional)

Addresses

  • Rua Pedro Nunes, 3030 - 199, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology - Bioproducts Biomaterials
  • Engineering and Technology - Nano-technology - Nano-materials
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Intermediate (B1)
Portuguese (Mother tongue)
Education
Degree Classification
2023/02/08 - 2023/04/05
Concluded
 Seed Tech Transfer (Outros)
Universidade de Coimbra, Portugal
2022/10/04 - 2022/10/25
Concluded
 ineoSTART - Transformar tecnologias e ideias em negócios (Outros)
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2022/10/17 - 2022/10/18
Concluded
 Royce Training "3D Bioprinting for Healthcare Applications" (Outros)
The Henry Royce Institute, United Kingdom
2022/06/26 - 2022/10/07
Concluded
 CCAIXIZ/4 | Tech Transfer Leadership in Life Sciences Course (Outros)
CaixaForum Barcelona, Spain

Barcelona School of Management, Spain
2018/11/05 - 2018/11/08
Concluded
 Science Communication Course (Outros)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/01/11 - 2018/01/11
Concluded
 Good Manufacturing Practices in the Pharmaceutical Industry: how transform rules into productivity tools (8 hours) (Outros)
Universidade da Beira Interior, Portugal
2012/01/01 - 2016/03/14
Concluded
 Bioquímica (Doutoramento)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
""miRNA-29 Bioseparation and Target Delivery Strategies for Alzheimer’s Disease"" (THESIS/DISSERTATION)
 Excellent (20 values)
2013/11/22 - 2013/11/24
Concluded
 I Hands-on Course on Fluorescence Microscopy and Image Analysis (Outros)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012/02/13 - 2012/02/17
Concluded
 Hands on Course, NMR- From Theory to Practice (29.5 hours) (Outros)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2009/09 - 2011/06
Concluded
 Bioquímica (Mestrado)
Universidade da Beira Interior Faculdade de Ciências, Portugal
"Development of new therapeutic strategies for siRNA delivery" (THESIS/DISSERTATION)
 18 values
2011/05/14 - 2011/05/14
Concluded
 Intensive Course on Antibiotics (8 hours) (Outros)
Universidade da Beira Interior, Portugal
2010/09/14 - 2010/09/16
Concluded
 Young Researchers Training (Outros)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2006/09 - 2009/07
Concluded
 Bioquímica (Licenciatura)
Universidade da Beira Interior Faculdade de Ciências, Portugal
"Monitorização terapêutica de antiarrítmicos e glucósidos cardiotónicos: a sua importância em toxicologia clínica" (THESIS/DISSERTATION)
 15 values
Affiliation

Science

Category
Host institution 		Employer
2021/03/01 - Current Science and Technology Management Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2020/01/01 - Current Researcher (Research) Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
2020/01/01 - 2021/02/28 Researcher (Research) Prodeq - Associação Para O Desenvolvimento Da Engenharia Química, Portugal
Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
2019/09/16 - 2019/12/31 Postdoc (Research) Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
Universidade de Coimbra Centro de Engenharia Mecânica Materiais e Processos, Portugal
2016/07/01 - 2019/08/16 Postdoc (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/04/01 - 2019/05/16 Visiting Researcher (Research) Biocant Associação de Transferência de Tecnologia, Portugal
Biocant Associação de Transferência de Tecnologia, Portugal
2012/01/01 - 2016/03/14 Researcher (Research) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2010/09/01 - 2011/12/31 Researcher (Research) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Others

Category
Host institution 		Employer
2021/03/01 - Current Responsible for the Cell Biology Unit Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2013 - 2016 Responsible for the Chromatography laboratory Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Projects

Grant

Designation Funders
2019/09 - 2019/12 Produção de tubos de PVC isento de ftalatos
POCI-01-0247-FEDER-017789
Post-doc Fellow
Universidade de Coimbra, Portugal
 Agência Nacional de Inovação SA
Concluded
2012/01/01 - 2015/12/31 miRNA-29 bioseparation and target delivery strategies for Alzheimer's disease
SFRH/BD/81914/2011
PhD Student Fellow
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012/01 - 2015/12 miRNA-29 bioseparation and target delivery strategies for Alzheimer's disease
SFRH/BD/81914/2011
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2025/04/01 - Current Minepipe - Desenvolvimento de tubos de alta performance para a indústria mineira
MPr-2023-7 / MPr-2023-8
Researcher
SIID – I&D Empresarial – Operações em Copromoção funded by PT2030
Ongoing
2025/03/01 - Current GreenAgro - Desenvolvimento de uma nova tinta biobaseada para indústria automóvel
MPr-2023-7 / MPr-2023-8
Researcher
SIID – I&D Empresarial – Operações em Copromoção
Ongoing
2025/03/01 - Current BioDrive - Desenvolvimento de fibras de tecido não tecido (TNT) de fonte renovável para a indústria automóvel
MPr-2023-7 / MPr-2023-8
Researcher
SIID – I&D Empresarial – Operações em Copromoção funded by PT2030
Ongoing
2025/03/01 - Current BioCoating - Desenvolvimento de uma nova tinta biobaseada para indústria automóvel
MPr-2023-7 / MPr-2023-8
Researcher
SIID – I&D Empresarial – Operações em Copromoção funded by PT2030
Ongoing
2024/11/01 - Current Alchemissts - Alternative Chemicals and Materials integrating Safety, Sustainability, new Production technologies and Socio-economic aspects
HORIZON-CL4-2024-RESILIENCE-01
Researcher
Horizon 2020
Ongoing
2022/07/01 - Current ActiveStent - Funcionalização sustentável de stents para prevenção de infeções do trato urinário
CENTRO-01-0145-FEDER-181221
Researcher
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluded
2022/09 - 2025 Sustainable Plastics
C644912598-00000021
Researcher
Ongoing
2022/09/01 - 2024/12/31 Dextran-PCL-based nerve guidance conduits 3D printed for nerve Regeneration
CI22-00190
Researcher
CaixaForum Barcelona
Concluded
2022/09 - 2023/06 3DNerveGen / Produção de dispositivos médicos biodegradáveis para regeneração nervosa periférica por impressão 3D
Projetos de Ignição e Provas de Conceito INOVC+
Researcher
Concluded
2022/05 - 2023/04 (Less)PlasticBrain: Bio Replacing Plasticizers - Impact in the Human Brain Development
Prémios Semente de Investigação Científica Interdisciplinar
Researcher
Universidade de Coimbra, Portugal
Concluded
2018/01/01 - 2021/09/30 Ribonucleases as tools to combat the foodborne pathogen Campylobacter jejuni
PTDC/BIA-BQM/28479/2017
Researcher
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/04/01 - 2019/10/31 Nonsense-mediated mRNA decay in genetic diseases and cancer: key players, mechanisms, and a novel approach for suppression therapy
PTDC/BIM-MEC/3749/2014
Researcher
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/06/01 - 2019/06/30 Determination of the architecture and the RNA degradation strategy of Ribonuclease R: implications for pathogen control.
Provided by PTCRIS: 140024
PTDC/BIA-MIC/1399/2014
Post-doc Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/06/01 - 2014/12/31 Pre-miR-29 bioseparation and target delivery strategies for Alzheimer's Disease
128832
Provided by PTCRIS: 128832
EXPL/BBB-BIO/1056/2012
Researcher
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Pereira P, Sousa F, Figueiras AR. "Polyplexes as Nanovectors for Gene Therapy". In Biotechnology, 179-223. Houston, United States: Studium Press LLC (ISBN: 1-62699-025-5), 2013.
    Published
Conference poster
  1. Pereira, Patrícia. "3D printing of wound dressing materials using a light-mediated technology". Paper presented in 35th iSMIT 2024 Meeting, 2024.
  2. Pereira, P.. "Development of a novel dextran and PCL-based biomaterial ink for nerve regeneration". Paper presented in 35th iSMIT 2024 Meeting, 2024.
  3. Pereira, P.. "Targeting Alzheimer’s Disease using Multivalent Copolymers". Paper presented in 35th iSMIT 2024 Meeting, 2024.
  4. Pereira, Patrícia. "Poly(ester amide)s membranes for the prevention of tendon adhesions". Paper presented in CEMMPRE Meeting 2023, 2023.
  5. Pereira, Patrícia. "a-Amino Acid based Poly(ester amide)s: a promising material for the prevention of tendon adhesions". Paper presented in Ciência 2023 – Encontro com a Ciência e a Tecnologia em Portugal, 2023.
  6. Cruz, Sandra; Santo, Daniela; Pereira, Patrícia; Rodrigues, Lisa ; Gonçalves, Teresa; I. Carvalho; Henriques, Mariana; Cavaleiro, Albano; Carvalho, Sandra. "Sustainable functionalization of stents to prevent urinary tract infections". Paper presented in SICT 2023 Surfaces, Interfaces and Coatings Technologies International conference, 2023.
  7. Alípio, AF; Bárria, C.; Pereira, Patrícia; Arraiano, Cecília Maria; Domingues, Susana. Corresponding author: Domingues, Susana. "RNase R, a key factor for Streptococcus pneumoniae biofilm formation". Paper presented in AIMS meeting 2023, 2023.
  8. Cruz S, Pereira P, Rodrigues L, Gonçalves T, Carvalho I, Cavaleiro A, Carvalho S. "ActiveStent - Sustainable functionalisation of stents to prevent urinary tract infections". Paper presented in CEMMPRE meeting 2022, 2022.
  9. Saraiva S, Pereira P, Paula CTB, Rebelo RC, Coelho JFJ, Serra AC, Fonseca AC. "Development of electrospun mats based on hydrophobic hydroxypropyl cellulose esters". Paper presented in European Polymer Federation Congress 2022, 2022.
  10. Paula CTB, Pereira P, Coelho JFJ, Fonseca AC, Serra AC. "Biocompatible hydrogels with controlled degradation by visible light". Paper presented in Encontro Ciência 2022, 2022.
  11. Castro LS, Pereira P, Sousa F, Coutinho JAP, Tavares APM, Freire MG, Pedro AQ. "Improvement of recombinant proteins purification by the use of ionic liquids as adjuvants in aqueous two-phase systems". Paper presented in MicroBiotec’19 - Congress of Microbiology and Biotechnology. Coimbra, Portugal, 2019.
  12. Santos T, Pereira P, Pedro AQ, Dias JS, Viegas A, Queiroz JA, Cabrita EJ, Cruz C. "Nucleolin/miR-149 complex: A strategy in the target of prostate cancer cells". Paper presented in III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Aging and Cancer. Covilhã, Portugal, 2019.
  13. Carapito R, Neves M, Pereira P, Pedro AQ, Queiroz JA, Freire MG, Sousa F. "Ionic liquids-based supports for the separation of nucleic acids". Paper presented in III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Aging and Cancer. Covilhã, Portugal, 2019.
  14. Riscado MR, Baptista B, Queiroz JA, Pereira P, Sousa F. "The role of miR-9 and miR-29 biopharmaceuticals in Alzheimer’s disease". Paper presented in III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Aging and Cancer. Covilhã, Portugal, 2019.
  15. Figueiredo J, Pereira P, Valente S, Magalhães E, Mergny J-L, Cruz C. "A reversible miRNA hairpin G- quadruplex Conformational Transition and its biological relevance". Paper presented in III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Aging and Cancer. Covilhã, Portugal, 2019.
  16. Santos T, Pereira P, Pedro AQ, Dias J, Viegas A, Cabrita EJ, Cruz C. "miR-149 G-quadruplex recognition by the nucleolin protein in prostate cancer cells". Paper presented in PTNMR Meeting, SMASH - Small Molecule NMR Conference. Porto, Portugal, 2019.
  17. Quental MJ, Pedro AQ, Pereira P, Sharma M, Queiroz JA, Coutinho JAP, Sousa F, Freire MG. "Bio-based ionic liquids as integrated extraction-preservation strategies in RNA bioprocessing". Paper presented in ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology. Sitges, Spain, 2019.
  18. Neves MC, Pereira P, Pedro AQ, Martins JC, Trindade T, Queiroz JA, Freire MG, Sousa F. "Isolation of nucleic acids using novel ionic-liquid-modified stationary phases". Paper presented in ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology. Sitges, Spain, 2019.
  19. Pedro AQ, Pereira P, Quental MJ, Carvalho AP, Santos SM, Queiroz JA, Sousa F, Freire MG. "Stabilization of recombinant RNA using biological-based ionic liquids". Paper presented in ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology. Sitges, Spain, 2019.
  20. Riscado MR, Tavares AP, Pereira P, Sousa F. "Studying the interaction between carbon nanotubes and RNA for cellular delivery". Paper presented in XIV Annual CICS-UBI Symposium. Covilhã, Portugal, 2019.
  21. Santos T, Pereira P, Dias J, Viegas A, Queiroz J, Cabrita EJ, Cruz C. "The pre-miRNA-149 – Nucleolin complex: an integrated strategy to assembly the complex for the targeting of prostate cancer cells". Paper presented in XIV Annual CICS-UBI Symposium. Covilhã, Portugal, 2019.
  22. Castro LS, Almeida MR, Pereira P, Passarinha L, Sousa F, Coutinho JAP, Tavares APM, Freire MG, Pedro AQ. "Aqueous two-phase systems comprising ionic liquids for the extraction of recombinant proteins". Paper presented in XIV Annual CICS-UBI Symposium. Covilhã, Portugal, 2019.
  23. Viegas SC, Matos RG, Pereira P, Arraiano CM. "Pinpointing the residues responsible for Dis3L2 specificity". Paper presented in mRNA Turnover: Mechanisms, Regulation and their Implication in Infectious and Age-Related Diseases. Marriott Chateau Champlain, Montréal, Canada, 2019.
  24. Pereira P, Viegas SC, Sousa F, Arraiano CM. "Production, Purification and Delivery of recombinant pre-miR-29". Paper presented in 3rd International Conference on the Long and the Short of Non-Coding RNAs. Chania, Crete, Greece, 2019.
  25. Castro LS, Almeida MR, Pereira P, Passarinha L, Sousa F, Coutinho JAP, Tavares APM, Pedro AQ, Freire MG. "Improving the purification of recombinant proteins by the use of ionic liquids as adjuvants in aqueous two-phase systems". Paper presented in Jornadas CICECO 2019 – Where Science Meets Society. Aveiro, Portugal, 2019.
  26. Quental MV, Pedro AQ, Pereira P, Sharma M, Queiroz JA, Coutinho JAP, Sousa F, Freire MG. "Integrated extraction-preservation strategies for RNA bioprocessing using biobased ionic liquids". Paper presented in Jornadas CICECO 2019 – Where Science Meets Society. Aveiro, Portugal, 2019.
  27. Neves MC, Pereira P, Pedro AQ, Martins JC, Trindade T, Queiroz JA, Freire MG, Sousa F. "Preparative chromatography of recombinant nucleic acids using ionic liquids as multimodal ligands". Paper presented in BIOTEC 2019 - National Congress of Biotechnology. Vigo, Spain, 2019.
  28. Quental MJ, Pedro AQ, Pereira P, Sharma M, Queiroz JA, Coutinho JAP, Sousa F, Freire MG. "Bio-based ionic liquids as extraction-preservation strategies in RNA bioprocessing". Paper presented in ISGC 2019. La Rochelle, France, 2019.
  29. Pereira P, Matos RG, Viegas SC, Arraiano CM. "Characterization of residues determining Dis3L2 functional specificity". Paper presented in IV NOVAhealth Genetics Workshop. Universidade NOVA de Lisboa, Lisboa, Portugal, 2019.
  30. Pereira P, Matos RG, Viegas SC, Arraiano C. "Dissecting protein residues responsible for Dis3L2 specificity". Paper presented in VIII National RNA Meeting: ptRNA2019. Porto, Portugal, 2019.
  31. Pedro AQ, Pereira P, Quental M.J, Carvalho A.P, Santos SM, Queiroz JA, Sousa F, Freire MG. "Biological-based ionic liquids as novel preservation media for recombinant RNA". Paper presented in ChemPor 2018 – 13th International Chemical and Biological Engineering Conference. Aveiro, Portugal, 2018.
  32. Santos T, Pereira P, Campello M.P.C., Paulo A., Cabrita E., Cruz C. "Nucleolin targeting by RNA G-quadruplex of pre-miR-149". Paper presented in International Symposium BIONIC 2018 – International Symposium Biology of non-canonical nucleic acids: from humans to pathogens. Padua, Italy, 2018.
  33. Pereira P, Neves MC, Pedro AQ, Rodrigues I, Martins JC, Trindade T, Queiroz JA, Freire MG, Sousa F. "Separation of nucleic acids using ionic-liquid functionalized macroporous supports". Paper presented in ChemPor 2018 – 13th International Chemical and Biological Engineering Conference. Aveiro, Portugal, 2018.
  34. Azevedo GM, Valente JFA, Sousa Â, Pedro AQ, Pereira P, Queiroz JA, Sousa F. "Effect of the purification conditions on the p53-pDNA stability and biological activity". Paper presented in XIII Annual CICS-UBI symposium. Universidade da Beira Interior, Covilhã, Portugal, 2018.
  35. Martins H, Santos T, Pereira P, Queiroz JA, Sousa F, Cruz C. "Production of G-quadruplex pre-miRNA-149 and its purification by affinity chromatography". Paper presented in XIII Annual CICS-UBI symposium. Covilhã, Portugal, 2018.
  36. Pedro AQ, Antunes JA, Pereira P, Passarinha LA, Sousa F, Coutinho JAP, Freire MG. "Bioprocessing of interferon alfa 2b using ionic-liquid-based systems". Paper presented in BPP 2017 - Biopartitioning and Purification Conference. Copenhagen, Denmark, 2017.
  37. Pereira P, Viegas SC, Sousa F, Arraiano C. "Modulating pre-miR-29b processing by changes in the 3’end". Paper presented in EMBO Conference – Eukaryotic RNA turnover. Oxford, United Kingdom, 2017.
  38. Pinto JM, Figueiró GA, Valente JFA, Pina AS, Pereira P, Queiroz JA, Roque ACA, Sousa F. "Recovery of recombinant microRNAs with modified magnetic nanoparticles". Paper presented in XII Annual CICS-UBI Symposium. Covilhã, Portugal, 2017.
  39. Barreira M, Pereira P, Pedro AQ, Figueiras R, Sousa F. "Ionic-liquid assisted-purification of pre-miR-29b for delivery in lung cancer cells". Paper presented in XII Annual CICS-UBI Symposium. Covilhã, Portugal, 2017.
  40. Viegas SC, Saramago M, Matos RG, Pereira P, Arraiano CM. "DIS-tinct fates for RNA targets: “U” can decide too!". Paper presented in XLI Jornadas da Sociedade Portuguesa de Genética. Aveiro, Portugal, 2017.
  41. Santos T, Ferreira J, Pereira P, Corvo M, Queiroz JA, Sousa F, Cruz C. "Selective isolation of G-quadruplex parallel sequences with naphthalene amine affinity support". Paper presented in G4thering – 6th International Meeting on Quadruplex Nucleic Acids. Prague, Czech Republic – Flash poster presentation, 2017.
  42. Pinto JM, Valente JFA, Pina AS, Pereira P, Queiroz JA, Roque CA, Sousa F. "Could it be possible to quickly determine the best ligands?". Paper presented in II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications. Covilhã, Portugal, 2017.
  43. Barreira M, Pereira P, Pedro A, Freire MG, Figueiras A, Sousa F. "Pre-miR-29 as lung cancer therapeutics: Improving purity with ionic liquids and delivery with functionalized nanosystems". Paper presented in II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications. Covilhã, Portugal, 2017.
  44. Martins JC, Neves MC, Pereira P, Queiroz JA, Freire MG, Sousa F. "New strategies for RNAs purification using ionic liquids ligands". Paper presented in II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications. Covilhã, Portugal, 2017.
  45. Santos T, Ferreira J, Pereira P, Corvo M, Queiroz JA, Sousa F, Cruz C. "New affinity support to isolate G4 parallel sequences". Paper presented in II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications. Covilhã, Portugal, 2017.
  46. Pereira P, Barahona S, Moreira RN, Dressaire C, Galego L, Silva IJ, Luís Â, Sousa F, Arraiano C. "Influence of recmobinant BolA in bacterial motility and biofilm formation". Paper presented in II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications. Covilhã, Portugal, 2017.
  47. Pedro AQ, Antunes J, Pereira P, Passarinha L, Coutinho JAP, Freire MG. "The role of biocompatible ionic liquids in the purification of recombinant Interferon alfa 2b". Paper presented in RPP9 – 9th International Conference on Recombinant Protein Production. Dubrovnik, Croatia, 2017.
  48. Santos T, Pereira P, Corvo M, Queiroz JA, Sousa F, Cruz C. "Synthesis of a novel support derived from naphthalene to purify G-quadruplex structures". Paper presented in V Ciclo de Conferências da Faculdade de Ciências. Covilhã, Portugal, 2017.
  49. Rodrigues J, Queiroz JA, Pereira P, Sousa F. "Pre-miR-9 and pre-miR-29 biosynthesis and purification". Paper presented in XI Annual CICS-UBI Symposium. Covilhã, Portugal, 2016.
  50. Almeida AM, Pereira P, Tomás J, Figueiredo V, Queiroz JA, Sousa F, Sousa Â. "Optimization of the supercoiled HPV16 E6/E7 DNA vaccine purification for in vitro transfection studies". Paper presented in VI Jornadas Nacionais de Ciências Biomédicas. Algarve, Portugal, 2016.
  51. Diamantino T, Pereira P, Queiroz JA, Sousa Â, Sousa F. "Minicircle DNA purification – a new methodology using monolithic supports". Paper presented in 9th National Meeting on Chromatography (9ENC) / XVI Latin-American Congress on Chromatography (XVI COLACRO). Lisboa, Portugal, 2016.
  52. Ferreira J, Santos T, Carvalho J, Pereira P, Queiroz JA, Sousa F, Cruz C. "Development of a chromatographic support using sinthesized G-quadruplex ligands". Paper presented in 9th National Meeting on Chromatography (9ENC) / XVI Latin-American Congress on Chromatography (XVI COLACRO). Lisboa, Portugal, 2016.
  53. Santos T, Pereira P, Sousa F, Queiroz JA, Cruz C. "Purification of the supercoiled G-quadruplex pDNA for in vitro transcription". Paper presented in 9th National Meeting on Chromatography (9ENC) / XVI Latin-American Congress on Chromatography (XVI COLACRO). Lisboa, Portugal, 2016.
  54. Pereira P, Pedro AQ, Tomás J, Sousa Â, Queiroz JA, Figueiras A, Sousa F. "Intra and Extracellular pre-miR-29b purification by an arginine monolithic support". Paper presented in 9th National Meeting on Chromatography (9ENC) / XVI Latin-American Congress on Chromatography (XVI COLACRO). Lisboa, Portugal, 2016.
  55. Diamantino T, Pereira P, Queiroz JA, Sousa Â, Sousa F. "Minicircle DNA purification - A new methodology using monolithic supports". Paper presented in MicroBiotec’15 - Congress of Microbiology and Biotechnology. Évora, Portugal, 2015.
  56. Pereira P, Pedro AQ, Tomás J, Sousa Â, Queiroz JA, Figueiras A, Sousa F. "Polyplexes-mediated delivery of pre-miR-29b for Alzheimer’s disease therapeutics". Paper presented in I International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Endocrinology and Neurosciences. Covilhã, Portugal, 2015.
  57. Rodrigues J, Queiroz JA, Pereira P, Sousa F. "Pre-miR-9 biosynthesis and purification: possible implications in Alzheimer’s disease". Paper presented in I International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Endocrinology and Neurosciences. Covilhã, Portugal, 2015.
  58. Santos T, Pereira P, Sousa F, Queiroz JA, Cruz C. "Purification of G-quadruplex supercoiled plasmid DNA with chromatographic supports based on amino acids". Paper presented in I International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Endocrinology and Neurosciences. Covilhã, Portugal, 2015.
  59. Carvalho J, Ferreira J, Pereira P, Coutinho E, Sousa F, Cabrita EJ, Queiroz JA, Cruz C. "Synthesis and characterization of novel naphthalene and quinoline-based G-quadruplex ligands for cancer therapy". Paper presented in I International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Endocrinology and Neurosciences. Covilhã, Portugal, 2015.
  60. Almeida AM, Tomás J, Pereira P, Figueiredo V, Queiroz JA, Sousa F, Sousa Â. "Implementation of biotechnological platform to obtain a HPV-16 E6 and E7 plasmid DNA vaccine". Paper presented in I International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Endocrinology and Neurosciences. Covilhã, Portugal, 2015.
  61. Almeida AM, Pereira P, Tomás J, Figueiredo V, Queiroz JA, Sousa F, Sousa Â. "Biotechnological approach to prepare a DNA vaccine for HPV induced-cervical cancer treatment". Paper presented in 30th Annual International Papillomavirus Conference and Clinical Workshops. Lisboa, Portugal, 2015.
  62. Almeida AM, Pereira P, Tomás J, Figueiredo V, Queiroz JA, Sousa F, Sousa Â. "Optimization of the supercoiled HPV16 E6/E7 DNA vaccine purification for in vitro transfection studies". Paper presented in VI Jornadas Nacionais de Ciências Biomédicas. Universidade do Algarve, Algarve, Portugal, 2015.
  63. Afonso A, Pereira P, Queiroz JA, Sousa Â, Sousa F. "A breakthrough optimization of O-phospho-L-tyrosine affinity chromatography to purify pre-miR-29". Paper presented in IX Annual CICS-UBI Symposium. Covilhã, Portugal, 2014.
  64. Pereira P, Sousa Â, Maia CJ, Queiroz JA, Correia IJ, Figueiras A, Sousa F. "Pre-miR-29 biosynthesis and purification: possible implications in Alzheimer’s disease". Paper presented in MicroBiotec’13 - Congress of Microbiology and Biotechnology. Aveiro, Portugal, 2013.
  65. Afonso A, Pereira P, Sousa Â, Queiroz JA, Sousa F. "Purification of pre-miR-29 using a new affinity chromatographic strategy optimized by Design of Experiments". Paper presented in 8th Portuguese National Meeting of Chromatography (8ENC). Universidade da Beira Interior, Covilhã, Portugal, 2013.
  66. Afonso A, Pereira P, Queiroz JA, Sousa Â, Sousa F. "Development of an O-phospho-L-tyrosine affinity chromatography to purify pre-miR-29 using Design of Experiments". Paper presented in V Symposium on Bioengineering. Faculty of Engineering of the University of Porto, Porto, Portugal, 2013.
  67. Pereira P, Sousa Â, Correia IJ, Figueiras AR, Sousa F. "Improved native pre-miR-29 purification with lysine-affinity chromatography". Paper presented in 19th International Symposium on Separation Sciences – New achievements in Chromatography. Porec, Croatia, 2013.
  68. Pereira P, Sousa Â, Correia IJ, Figueiras AR, Sousa F. "Exploiting multiple interactions in pre-miR-29 purification by arginine-affinity chromatography". Paper presented in 19th International Symposium on Separation Sciences – New achievements in Chromatography. Porec, Croatia, 2013.
  69. Pereira P, Maia CJ, Correia IJ, Figueiras A, Sousa F. "Biosynthesis of pre-miR-29 for application in neurodegenerative disorders". Paper presented in ECCE9 – ECAB2 (9th European Congress of Chemical Engineering and 2nd European Congress of Applied Biotechnology). The Hague, The Netherlands, 2013.
  70. Afonso A, Pereira P, Sousa Â, Sousa F. "Pre-miR-29 isolation using a new chromatographic strategy with tyrosine-agarose". Paper presented in ECCE9 – ECAB2 (9th European Congress of Chemical Engineering and 2nd European Congress of Applied Biotechnology). The Hague, The Netherlands, 2013.
  71. Pereira P, Jorge A, Pais ACC, Sousa F, Figueiras A. "Characterization of polyplexes containing small RNA". Paper presented in Conference CEF - Center for Pharmaceutical Studies. Coimbra, Portugal, 2012.
  72. Pereira P, Maia C, Correia IJ, Figueiras A, Sousa F. "Biosynthesis and purification of siNOX1 for application in neurodegenerative disorders". Paper presented in ESBES - ISPPP (9th European Symposium on Biochemical Engineering Science and 32nd International Symposium on the Separation of Proteins, Peptides and Polynucleotides). Istanbul, Turkey, 2012.
  73. Pereira P, Correia IJ, Figueiras AR, Sousa F. "miRNA-29 bioseparation and target delivery strategies for Alzheimer disease". Paper presented in V Conference of Technology and Health. Instituto Politécnico da Guarda, Guarda, Portugal, 2012.
  74. Pereira P, Jorge A, Martins R, Pais ACC, Sousa F, Figueiras AR. "Structural and functional characterization of polyplexes for small RNA delivery". Paper presented in 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. Istanbul, Turkey, 2012.
Exhibition catalog
  1. Rita G. Fonseca; Aline Kuster; Pedro P. Fernandes; Mahmoud Tavakoli; Patrícia Pereira; José R. Fernandes; Francesco De Bon; et al. Facile Synthesis of Highly Stretchable, Tough, and Photodegradable Hydrogels (Adv. Healthcare Mater. 22/2023). 2023.
    10.1002/adhm.202370133
  2. Carvalho J, Ferreira J, Pereira P, Coutinho E, Guédin A, Nottelet P, Salgado GF, Mergny J-L, Queiroz JA, Sousa F, Cruz C. Issue Front Cover: Stabilization of novel immunoglobulin switch regions G-quadruplexes by naphthalene and quinoline-based ligands. This figure was originally published in Tetrahedron, 2016, 72, 1229–1237; doi: 10.1016/j.tet.2016.0, 2016.
Journal article
  1. Sofia Saraiva; Francisca Rénio; Patrícia Pereira; Patrícia Santos; Carlos T. B. Paula; Amílcar Ramalho; Arménio C. Serra; Ana C. Fonseca. "Tackling the Problem of Tendon Adhesions: Physical Barriers Prepared from a-Amino Acid-Based Poly(ester amide)s". Polymers (2025): https://doi.org/10.3390/polym17030395.
    10.3390/polym17030395
  2. Silva, Rute; Rebelo, Rafael C.; Paula, Carlos T.B.; Pereira, Patrícia; Fonseca, Ana C.; Serra, Arménio C.; Coelho, Jorge F.J.. "All-cellulose resin for 3D printing hydrogels via digital light processing (DLP)". International Journal of Biological Macromolecules (2025): 141389. https://doi.org/10.1016/j.ijbiomac.2025.141389.
    10.1016/j.ijbiomac.2025.141389
  3. Saraiva, Sofia; Pereira, Patrícia; Santos, Patrícia; Ramalho, Amílcar; Serra, Arménio C.; Fonseca, Ana C.. "Electrospun mats from a-amino acid based poly(ester amide)s: A promising material for the prevention of tendon adhesions". Reactive and Functional Polymers 205 (2024): 106067. http://dx.doi.org/10.1016/j.reactfunctpolym.2024.106067.
    10.1016/j.reactfunctpolym.2024.106067
  4. Fernandes, Mónica C. S.; Branco, Rita; Pereira, Patrícia; Coelho, Jorge F. J.; Morais, Paula V.; Serra, Arménio C.. "Antimicrobial Activity of Copolymer Structures from Bio-Based Monomers". Biomacromolecules (2024): http://dx.doi.org/10.1021/acs.biomac.4c01203.
    10.1021/acs.biomac.4c01203
  5. Rafael C. Rebelo; Blanca Vélez Báguena; Patrícia Pereira; Rui Moreira; Jorge F. J. Coelho; Arménio C. Serra. "Biocompatible Cellulose-Based Superabsorbents for Personal Care Products". Journal of Polymers and the Environment (2024): https://doi.org/10.1007/s10924-024-03315-4.
    10.1007/s10924-024-03315-4
  6. Paula, Carlos T.B.; Saraiva, Sofia; Pereira, Patrícia; Coelho, Jorge F.J.; Fonseca, Ana C.; Serra, Arménio C.. "ROS-responsive electrospun poly(amide thioketal) mats for wound dressing applications". Polymer 294 (2024): 126697. http://dx.doi.org/10.1016/j.polymer.2024.126697.
    10.1016/j.polymer.2024.126697
  7. Carlos T.B. Paula; Ana Leandro; Patrícia Pereira; Jorge F.J. Coelho; Ana C. Fonseca; Arménio C. Serra. "Fast-Gelling Polyethylene Glycol/Polyethyleneimine Hydrogels Degradable by Visible-Light". Macromolecular Bioscience (2023):
    10.1002/mabi.202300289
  8. Rita G. Fonseca; Aline Kuster; Pedro P. Fernandes; Mahmoud Tavakoli; Patrícia Pereira; José R. Fernandes; Francesco De Bon; et al. "Facile Synthesis of Highly Stretchable, Tough, and Photodegradable Hydrogels". Advanced Healthcare Materials 12 (2023):
    10.1002/adhm.202300918
  9. Patrícia Pereira; Ana S. Neto; Ana S. Rodrigues; Inês Barros; Catarina Miranda; João Ramalho-Santos; Luís Pereira de Almeida; et al. "In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue Regeneration". Polymers (2023): https://doi.org/10.3390/polym15102256.
    10.3390/polym15102256
  10. Oliveira, Andreia S. R.; Pereira, Patrícia; Mendonça, Patrícia V.; Fonseca, Ana C.; Simões, Sérgio; Serra, Arménio C.; Coelho, Jorge F. J.. "Novel degradable amphiphilic 4-arm star PLA-b-POEOA and PLGA-b-POEOA block copolymers: synthesis, characterization and self-assembly". Polymer Chemistry 14 2 (2023): 161-171. http://dx.doi.org/10.1039/d2py01216b.
    10.1039/d2py01216b
  11. Rebelo, Rafael C.; Ribeiro, Diana C. M.; Pereira, Patrícia; De Bon, Francesco; Coelho, Jorge F. J.; Serra, Arménio C.. "Cellulose-based films with internal plasticization with epoxidized soybean oil". Cellulose 30 3 (2022): 1823-1840. http://dx.doi.org/10.1007/s10570-022-04997-6.
    Open access • 10.1007/s10570-022-04997-6
  12. Paula, Carlos T.B.; Madeira, Ana B.; Pereira, Patrícia; Branco, Rita; Morais, Paula V.; Coelho, Jorge F.J.; Fonseca, Ana C.; Serra, Arménio C.. "ROS-degradable PEG-based wound dressing films with drug release and antibacterial properties". European Polymer Journal 177 (2022): 111447. http://dx.doi.org/10.1016/j.eurpolymj.2022.111447.
    Open access • 10.1016/j.eurpolymj.2022.111447
  13. Fonseca, Rita G.; De Bon, Francesco; Pereira, Patrícia; Carvalho, Francisca M.; Freitas, Marta; Tavakoli, Mahmoud; Serra, Arménio C.; Fonseca, Ana C.; Coelho, Jorge F.J.. "Photo-degradable, tough and highly stretchable hydrogels". Materials Today Bio 15 (2022): 100325. http://dx.doi.org/10.1016/j.mtbio.2022.100325.
    Open access • 10.1016/j.mtbio.2022.100325
  14. Pereira, Patrícia Alexandra; Serra, Maria Elisa Silva; Serra, Arménio C.; Coelho, Jorge F. J.. "Application of vinyl polymer-based materials as nucleic acids carriers in cancer therapy". WIREs Nanomedicine and Nanobiotechnology 14 5 (2022): http://dx.doi.org/10.1002/wnan.1820.
    10.1002/wnan.1820
  15. Neto, Ana S.; Pereira, Patrícia; Fonseca, Ana C.; Dias, Carla; Almeida, Mariana C.; Barros, Inês; Miranda, Catarina O.; et al. "Highly Porous Composite Scaffolds Endowed with Antibacterial Activity for Multifunctional Grafts in Bone Repair". Polymers 13 24 (2021): 4378. http://dx.doi.org/10.3390/polym13244378.
    10.3390/polym13244378
  16. Paula, Carlos T.B.; Pereira, Patrícia; Coelho, Jorge F.J.; Fonseca, Ana C.; Serra, Arménio C.. "Development of light-degradable poly(urethane-urea) hydrogel films". Materials Science and Engineering: C 131 (2021): 112520. http://dx.doi.org/10.1016/j.msec.2021.112520.
    10.1016/j.msec.2021.112520
  17. Pereira, Patrícia; Pedro, Augusto Q.; Neves, Márcia C.; Martins, João C.; Rodrigues, Inês; Freire, Mara G.; Sousa, Fani. "Efficient Isolation of Bacterial RNAs Using Silica-Based Materials Modified with Ionic Liquids". Life 11 10 (2021): 1090. http://dx.doi.org/10.3390/life11101090.
    10.3390/life11101090
  18. Pereira, Patrícia; Serra, Arménio C.; Coelho, Jorge F.J.. "Vinyl Polymer-based technologies towards the efficient delivery of chemotherapeutic drugs". Progress in Polymer Science 121 (2021): 101432. http://dx.doi.org/10.1016/j.progpolymsci.2021.101432.
    10.1016/j.progpolymsci.2021.101432
  19. Saraiva, Sofia; Pereira, Patrícia; Paula, C.T.; Rebelo, R.C.; Coelho, Jorge F.J.; Serra, Arménio C.; Fonseca, Ana C.. "Development of electrospun mats based on hydrophobic hydroxypropyl cellulose derivatives". Materials Science and Engineering: C (2021): 112498. http://dx.doi.org/10.1016/j.msec.2021.112498.
    10.1016/j.msec.2021.112498
  20. Castro, Leonor S.; Lobo, Guilherme S.; Pereira, Patrícia; Freire, Mara G.; Neves, Márcia C.; Pedro, Augusto Q.. "Interferon-Based Biopharmaceuticals: Overview on the Production, Purification, and Formulation". Vaccines 9 4 (2021): 328. http://dx.doi.org/10.3390/vaccines9040328.
    10.3390/vaccines9040328
  21. J.F.A. Valente; P. Pereira; A. Sousa; J.A. Queiroz; F. Sousa. "Effect of Plasmid DNA Size on Chitosan or Polyethyleneimine Polyplexes Formulation". Polymers (2021): https://doi.org/10.3390/polym13050793.
    10.3390/polym13050793
  22. Neves, Márcia C.; Pereira, Patrícia; Pedro, Augusto Q.; Martins, João C.; Trindade, Tito; Queiroz, João A.; Freire, Mara G.; Sousa, Fani. "Improved ionic-liquid-functionalized macroporous supports able to purify nucleic acids in one-step". Materials Today Bio (2020): 100086. http://dx.doi.org/10.1016/j.mtbio.2020.100086.
    Accepted • 10.1016/j.mtbio.2020.100086
  23. Pereira, Patrícia; Barreira, Maria; Cruz, Carla; Tomás, Joana; Luís, Ângelo; Pedro, Augusto Q.; Queiroz, João A.; Sousa, Fani. "Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes". Pharmaceuticals 13 10 (2020): 314. http://dx.doi.org/10.3390/ph13100314.
    10.3390/ph13100314
  24. Castro, Leonor S.; Pereira, Patrícia; Passarinha, Luís A.; Freire, Mara G.; Pedro, Augusto Q.. "Enhanced performance of polymer-polymer aqueous two-phase systems using ionic liquids as adjuvants towards the purification of recombinant proteins". Separation and Purification Technology 248 (2020): 117051. http://dx.doi.org/10.1016/j.seppur.2020.117051.
    Published • 10.1016/j.seppur.2020.117051
  25. Cruz, Carla; Pedro, Augusto Q.; Carvalho, Josué; Santos, Tiago; Talhada, Daniela; Paiva, Artur; Queiroz, João A.; et al. "Nucleolin as a potential biomarker for canine malignant neoplasia". Research in Veterinary Science (2020): http://dx.doi.org/10.1016/j.rvsc.2020.10.004.
    10.1016/j.rvsc.2020.10.004
  26. Azevedo, G.M.; Valente, J.F.A.; Sousa, A.; Pedro, A.Q.; Pereira, P.; Sousa, F.; Queiroz, J.A.. "Effect of Chromatographic Conditions on Supercoiled Plasmid DNA Stability and Bioactivity". Applied Sciences 9 23 (2019): 5170. http://dx.doi.org/10.3390/app9235170.
    Open access • Published • 10.3390/app9235170
  27. Santos, Tiago; Pereira, Patrícia; Campello, Maria Paula Cabral; Paulo, António; Queiroz, João A.; Cabrita, Eurico; Cruz, Carla. "RNA G-quadruplex as supramolecular carrier for cancer-selective delivery". European Journal of Pharmaceutics and Biopharmaceutics 142 (2019): 473-479. http://dx.doi.org/10.1016/j.ejpb.2019.07.017.
    Published • 10.1016/j.ejpb.2019.07.017
  28. Santos, Tiago; Pereira, Patrícia; Queiroz, João A.; Cruz, Carla; Sousa, Fani. "Plasmid production and purification: An integrated experiment-based biochemistry and biotechnology laboratory course". Biochemistry and Molecular Biology Education 47 6 (2019): 638-643. http://dx.doi.org/10.1002/bmb.21290.
    Published • 10.1002/bmb.21290
  29. Pereira, Patrícia; Arraiano, Cecília M.. "A precision RNA degradation machinery shapes stem cell development". The Journal of Cell Biology 218 8 (2019): 2437-2438. http://dx.doi.org/10.1083/jcb.201906115.
    Published • 10.1083/jcb.201906115
  30. Maria V. Quental; Augusto Q. Pedro; Patrícia Pereira; Mukesh Sharma; João A. Queiroz; João A. P. Coutinho; Fani Sousa; Mara G. Freire. "Integrated Extraction-Preservation Strategies for RNA Using Biobased Ionic Liquids". ACS Sustainable Chemistry & Engineering (2019): https://doi.org/10.1021/acssuschemeng.9b00688.
    10.1021/acssuschemeng.9b00688
  31. Augusto Q. Pedro; Patrícia Pereira; Maria J. Quental; André P. Carvalho; Sérgio M. Santos; João A. Queiroz; Fani Sousa; Mara G. Freire. "Cholinium-Based Good’s Buffers Ionic Liquids as Remarkable Stabilizers and Recyclable Preservation Media for Recombinant Small RNAs". ACS Sustainable Chemistry & Engineering (2018): https://doi.org/10.1021/acssuschemeng.8b03900.
    10.1021/acssuschemeng.8b03900
  32. Góis, Joana R.; Reis, Fábio; Almeida, Ana M.; Pereira, Patrícia; Sousa, Fani; Serra, Arménio C.; Coelho, Jorge F.J.. "Preparation of well-defined brush-like block copolymers for gene delivery applications under biorelevant reaction conditions". Colloids and Surfaces B: Biointerfaces 169 (2018): 107-117. http://dx.doi.org/10.1016/j.colsurfb.2018.05.004.
    Published • 10.1016/j.colsurfb.2018.05.004
  33. Almeida, Ana M.; Tomás, Joana; Pereira, Patrícia; Queiroz, João A.; Sousa, Fani; Sousa, Ângela. "HPV-16 targeted DNA vaccine expression: The role of purification". Biotechnology Progress 34 2 (2018): 546-551. http://dx.doi.org/10.1002/btpr.2603.
    Published • 10.1002/btpr.2603
  34. Amorim, Lúcia F. A.; Gaspar, Rita; Pereira, Patrícia; Cernigoj, Urh; Sousa, Fani; Queiroz, João António; Sousa, Ângela. "Chromatographic HPV-16 E6/E7 plasmid vaccine purification employing L-histidine and 1-benzyl-L-histidine affinity ligands". ELECTROPHORESIS 38 22-23 (2017): 2975-2980. http://dx.doi.org/10.1002/elps.201700147.
    Published • 10.1002/elps.201700147
  35. Pereira, Patrícia; Pedro, Augusto Q.; Queiroz, João A.; Figueiras, Ana R.; Sousa, Fani. "New insights for therapeutic recombinant human miRNAs heterologous production: Rhodovolum sulfidophilum vs Escherichia coli". Bioengineered 8 5 (2017): 670-677. http://dx.doi.org/10.1080/21655979.2017.1284710.
    Published • 10.1080/21655979.2017.1284710
  36. Ferreira, João; Santos, Tiago; Pereira, Patrícia; Corvo, Marta C.; Queiroz, João A.; Sousa, Fani; Cruz, Carla. "Naphthalene amine support for G-quadruplex isolation". The Analyst 142 16 (2017): 2982-2994. http://dx.doi.org/10.1039/c7an00648a.
    Published • 10.1039/c7an00648a
  37. Pereira, Patrícia; Queiroz, João A.; Figueiras, Ana; Sousa, Fani. "Current progress on microRNAs-based therapeutics in neurodegenerative diseases". Wiley Interdisciplinary Reviews: RNA 8 3 (2016): e1409. http://dx.doi.org/10.1002/wrna.1409.
    Published • 10.1002/wrna.1409
  38. Diamantino, Tatiana; Pereira, Patrícia; Queiroz, João A.; Sousa, Ângela; Sousa, Fani. "Minicircle DNA purification using a CIM® DEAE-1 monolithic support". Journal of Separation Science 39 18 (2016): 3544-3549. http://dx.doi.org/10.1002/jssc.201600375.
    Published • 10.1002/jssc.201600375
  39. Pereira, Patrícia; Barreira, Maria; Queiroz, João A.; Veiga, Francisco; Sousa, Fani; Figueiras, Ana. "Smart micelleplexes as a new therapeutic approach for RNA delivery". Expert Opinion on Drug Delivery 14 3 (2016): 353-371. http://dx.doi.org/10.1080/17425247.2016.1214567.
    Published • 10.1080/17425247.2016.1214567
  40. Tiago Santos; Patricia N R Pereira; Fani Sousa; João A. Queiroz; Carla Cruz. "Purification of supercoiled G-quadruplex pDNA for in vitro transcription". Separation and Purification Technology 163 (2016): 59-71. http://dx.doi.org/10.1016/j.seppur.2016.02.036.
    10.1016/j.seppur.2016.02.036
  41. Carvalho, Josué; Ferreira, João; Pereira, P.; Coutinho, E.; Guédin, Aurore; Nottelet, Pierre; Salgado, Gilmar F.; et al. "Stabilization of novel immunoglobulin switch regions G-quadruplexes by naphthalene and quinoline-based ligands". Tetrahedron 72 9 (2016): 1229-1237. http://dx.doi.org/10.1016/j.tet.2016.01.022.
    Published • 10.1016/j.tet.2016.01.022
  42. Pereira, Patrícia; Pedro, Augusto Q.; Tomás, Joana; Maia, Cláudio J.; Queiroz, João A.; Figueiras, Ana; Sousa, Fani. "Advances in time course extracellular production of human pre-miR-29b from Rhodovulum sulfidophilum". Applied Microbiology and Biotechnology 100 8 (2016): 3723-3734. http://dx.doi.org/10.1007/s00253-016-7350-x.
    Published • 10.1007/s00253-016-7350-x
  43. Pereira, Patrícia A.; Tomás, Joana F.; Queiroz, João A.; Figueiras, Ana R.; Sousa, Fani. "Recombinant pre-miR-29b for Alzheimer´s disease therapeutics". Scientific Reports 6 1 (2016): http://dx.doi.org/10.1038/srep19946.
    Open access • Published • 10.1038/srep19946
  44. Pereira, Patrícia; Cruz, Carla; Queiroz, João A.; Figueiras, Ana; Sousa, Fani. "Analysis of pre-miR-29b binding conditions to amino acids by using a surface plasmon resonance biosensor". Analytical Methods 8 1 (2016): 205-213. http://dx.doi.org/10.1039/c5ay02329g.
    Published • 10.1039/c5ay02329g
  45. Pereira, P.; Queiroz, J.A.; Figueiras, A.; Sousa, F.. "Affinity approaches in RNAi-based therapeutics purification". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1021 (2016): 45-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979462515&partnerID=MN8TOARS.
    10.1016/j.jchromb.2016.01.022
  46. Pedro, A. Q.; Pereira, P.; Bonifácio, M. J.; Queiroz, J. A.; Passarinha, L. A.. "Purification of Membrane-Bound Catechol-O-Methyltransferase by Arginine-Affinity Chromatography". Chromatographia 78 21-22 (2015): 1339-1348. http://dx.doi.org/10.1007/s10337-015-2970-3.
    Published • 10.1007/s10337-015-2970-3
  47. Pereira, P.; Sousa, Â.; Queiroz, J.; Correia, I.; Figueiras, A.; Sousa, F.. "Purification of pre-miR-29 by arginine-affinity chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 951-952 1 (2014): 16-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893705000&partnerID=MN8TOARS.
    10.1016/j.jchromb.2014.01.020
  48. Afonso, A.; Pereira, P.; Queiroz, J.A.; Sousa, T.; Sousa, F.. "Purification of pre-miR-29 by a new O-phospho-l-tyrosine affinity chromatographic strategy optimized using design of experiments". Journal of Chromatography A 1343 (2014): 119-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899989051&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.03.071
  49. Pereira, P.; Sousa, T.; Queiroz, J.A.; Figueiras, A.; Sousa, F.. "Pharmaceutical-grade pre-miR-29 purification using an agmatine monolithic support". Journal of Chromatography A 1368 (2014): 173-182. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908209237&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.09.080
  50. Pereira, P.; Sousa, T.; Queiroz, J.; Figueiras, A.; Sousa, F.. "New approach for purification of pre-miR-29 using lysine-affinity chromatography". Journal of Chromatography A 1331 (2014): 129-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896715699&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.01.033
  51. Sousa, T.; Pereira, P.; Sousa, F.; Queiroz, J.A.. "Binding mechanisms for histamine and agmatine ligands in plasmid deoxyribonucleic acid purifications". Journal of Chromatography A 1366 (2014): 110-119. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907969355&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.09.031
  52. Pereira, Patrícia; Jorge, Andreia F.; Martins, Rita; Pais, Alberto A.C.C.; Sousa, Fani; Figueiras, Ana. "Characterization of polyplexes involving small RNA". Journal of Colloid and Interface Science 387 1 (2012): 84-94. http://dx.doi.org/10.1016/j.jcis.2012.07.088.
    Published • 10.1016/j.jcis.2012.07.088
Journal issue
  1. Pereira, P.. "Recent Trends and Technological Developments in Biopharmaceuticals Manufacturing". Life (2021): https://www.mdpi.com/journal/life/special_issues/biopharmaceuticals_manufacturing#info.
    Invited editor
Magazine article
  1. Leonor S Castro; Patrícia Pereira; Mara G Freire; Augusto Q Pedro. "Progress in the development of aqueous two-phase systems comprising ionic liquids for the downstream processing of protein-based biopharmaceuticals (Invited))", American Pharmaceutical Review, Separation and Purification, 2019, https://www.americanpharmaceuticalreview.com/Featured-Articles/518305-Progress-in-the-Development-of-Aqueous-Two-Phase-Systems-Comprising-Ionic-Liquids-for-the-Downstream-Processing-of-Protein-Based-Biopharmaceuticals/.
Thesis / Dissertation
  1. Pereira, P.. "miRNA-29 bioseparation and target delivery strategies for Alzheimer’s disease". PhD, 2016. https://ubibliorum.ubi.pt/handle/10400.6/4191.
  2. Pereira, P.. "Development of new therapeutic strategies for siRNA delivery". Master, Universidade da Beira Interior, 2011. https://ubibliorum.ubi.pt/handle/10400.6/3886.

Intellectual property

Patent
  1. Pereira, P.; Mara G. Freire; Fani Sousa; Augusto Q. Pedro. 2019. "Chromatographic Matriz, method and uses thereof".
    Granted/Issued
  2. Patrícia Pereira; Mara G Freire; Márcia Neves; Fani Sousa; João A Queiroz; João Martins; Augusto Q Pedro. 2019. "Matriz cromatográfica, método e seus usos". Portugal.
    Granted/Issued
  3. Neves, Márcia C.; Augusto Q. Pedro; Mara G. Freire; Pereira, Patrícia; Sousa, F; Martins, João C.; Queiroz, João A.. 2018. "Separação de ácidos nucleicos utilizando líquidos iónicos como ligandos cromatográficos multimodais em matrizes macroporosas,". Portugal.
  4. Pereira, P.; Fani Sousa; Carla Cruz. 2016. "Síntese e caracterização do suporte cromatográfico de L-tirosina para purificação de plasmídeos". Portugal.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/06/26 PolySyc. Coimbra Space Training Camp organized by the Institute Pedro Nunes (IPN) and ESA Space Solutions Portugal.
(Coimbra, Portugal)
2024/02/19 Cell biology unit. Seminar: Polymers, a valence in the IPN ecosystem.
(Coimbra, Portugal)
2023/10/25 Paula CT, Escobar I, Cerejo F, Pereira P, Serra A, Fonseca A, Coelho JF. Bioprinting of nerve guide tubes using DLP technology. CELLINK Partnership Conference
(Portsmouth, United Kingdom)
2023/08/01 Saraiva S, Pereira P, Serra AC, Fonseca AC. a-Amino acid based poly(ester amide)s in the prevention of tendon adhesions. 8th International Caucasian Symposium on Polymers & Advanced Materials
(Tbilisi, Georgia)
2023/06/28 NerveGen. Evento Final Projeto INOVC+.
(Coimbra, Portugal)
2023/06/21 PolySyc. Coimbra Space Training Camp organized by the Institute Pedro Nunes (IPN) and ESA Space Solutions Portugal.
(Coimbra, Portugal)
2023/05/12 (Less)Plastic Brain. Circular 23 - Conversas Circulares. Evento de Sustentabilidade da UC. Exploratório - Centro Ciência Viva de Coimbra
(Coimbra, Portugal)
2023/02/28 NerveGen. INOVC+.
(Casa das Artes de Miranda do Corvo, Portugal)
2023/02/22 Fonseca RG, De Bon F, Pereira P, Carvalho FM, Freitas M, Tavakoli M, Serra AC, Fonseca AC, Coelho JFJ. Photodegradable, tough and highly stretchable hydrogels. Polymers 2023 International Conference
(Bangkok, Thailand)
2023/02/01 Santo D, Fialho L, Grenho L, Fernandes MH, Carvalho I, Lima MJ, Nobre D, Marques SM, Castro D, Leite TR, Henriques M, Duarte F, Ramalho A, Cruz S, Pereira P, Rodrigues L, Gonçalves T, Cavaleiro A, Carvalho S. Surface Engineering: a powerful tool for biomedical applications. BIO'n'TEQ: Mostra Tecnológica de Biotecnologia
(Cantanhede, Portugal)
2023/01/05 NerveGen BioSTART: O que é ser empreendedor?
(Coimbra, Portugal)
2022/10/26 NerveGen Demo Day - ineoStart
(Coimbra, Portugal)
2022/07/19 Fonseca RG, De Bon F, Pereira P, Carvalho FM, Freitas M, Tavakoli M, Serra AC, Fonseca AC, Coelho J. Photo-degradable, tough and highly stretchable hydrogels. Junior EUROMAT2022
(Coimbra, Portugal)
2022/07/01 19. Paula CTB, Pereira P, Coelho JFJ, Fonseca AC, Serra AC. ROS/Light Degradable Poly(urethane/urea) hydrogel films. European Polymer Federation Congress 2022
(Prague, Czech Republic)
2022/06/13 Saraiva S, Pereira P, Paula CT, Rebelo RC, Coelho JFJ, Serra AC, Fonseca AC. Electrospinning of Hydroxypropyl Cellulose Esters with Long Aliphatic Chains. Bordeaux Polymer Conference-2022
(Bordeaux, France)
2019/09/07 Castro LS, Almeida MR, Pereira P, Passarinha L, Tavares APM, Coutinho JAP, Pedro AQ, Freire MG. Downstream processing of recombinant proteins using alternative purification platforms based on ionic liquids. ILSEPT – 4th International Conference on Ionic Liquids in Separation and Purification Tehcnology
(Sitges, Spain)
2019/07/04 Carapito R, Neves M, Pereira P, Pedro A, Queiroz JA, Freire MG, Sousa F. Ionic liquids-based supports for the purification of RNA. XIV Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2019/06/10 Castro LS, Almeida MR, Pereira P, Passarinha L, Tavares APM, Pedro AQ, Freire MG. Bioprocessing of recombinant proteins using alternative purification platforms. BIOTEC 2019 - Spanish National Congress of Biotechnology (BIOTEC)
(Vigo, Spain)
2018/07/05 Santos T, Pereira P, Campello MPC, Paulo A, Queiroz JA, Cabrita E, Cruz C. Acridine orange derivatives binding to RNA G-quadruplex and potential use in nucleolin targeting. XIII Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2018/07/02 Santos CRA, Gonçalves I, Cascalheira F, Quintela T, Pereira P, Sousa F. Seeking for Alzheimer's disease risk factors and therapies. Encontro Ciência’18 - Encontro com a Ciência e Tecnologia em Portugal
(Lisboa, Portugal)
2018/06/09 Cruz C, Santos T, Carvalho J, Andrade M, Pinto M, Montenegro L, Pedro AQ, Pereira P. Circulating nucleolin as a potential biomarker for canine tumors. XXIII Meeting of the Portuguese Society Animal Pathology
(Coimbra, Portugal)
2018/03/23 Santos T, Pereira P, Queiroz JA, Campello MPC, Paulo A, Sousa F, Cruz C. Nucleolin as target of RNA G-quadruplex aptamer for prostate cancer diagnosis. VI ENEQUI – Encontro Nacional de Estudantes de Química
(Covilhã, Portugal)
2017/11/11 Pereira P. Da molécula à disponibilização - Biotecnologia aliada às Ciências Farmacêuiticas. (Invited) III Congresso Científico Anual UBIPharma
Universidade da Beira Interior (Covilhã, Portugal)
2017/09/24 Martins JC, Neves MC, Pereira P, Pedro AQ, Queiroz JA, Freire MG, Sousa F. Functionalization of chromatographic matrices with ionic liquids for RNA purification. Biopartitioning and Purification (BPP)
(Copenhagen, Denmark)
2017/07/06 Martins JC, Neves MC, Pereira P, Pedro AQ, Queiroz JA, Freire MG, Sousa F. Synthesis and characterization of ionic liquid functionalized matrices for RNAs purification. XII Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2017/05/17 Antunes J, Pedro AQ, Pereira P, Sousa F, Passarinha L, Coutinho JA, Freire MG. Novel alternatives for interferon alfa-2b purification: chromatography vs ionic liquid aqueous biphasic systems. II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications
CICS-UBI (Covilhã, Portugal)
2017/05/17 Pereira P, Pedro AQ, Quental M, Santos S, Freire MG, Sousa F. Small RNA stabilization using cholinium-based ionic liquids. II International Congress in Health Sciences Research - Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications
CICS-UBI (Covilhã, Portugal)
2016/05/11 Pereira P. A Biotecnologia na preparação de biofármacos: o caso do microRNA-29 com aplicação na doença de Alzheimer. (Invited) Um dia com a Biotecnologia - Biomassa, Biocatálise e Bioprocessamento
Universidade de Aveiro (Aveiro, Portugal)
2015/12/10 Almeida AM, Pereira P, Tomás J, Figueiredo V, Queiroz JA, Sousa F, Sousa Â. DNA vaccine development for HPV treatment: biotechnological production, purification and in vitro application. MicroBiotec’15 - Congress of Microbiology and Biotechnology
Universidade de Évora (Évora, Portugal)
2015/12/10 Pereira P, Pedro AQ, Tomás J, Sousa Â, Queiroz JA, Figueiras A, Sousa F. A Biotechnological Platform for Pre-miRNAs Biosynthesis, Purification and Brain-Targeted Delivery for Alzheimer’s Disease. MicroBiotec’15 - Congress of Microbiology and Biotechnology
Universidade de Évora (Évora, Portugal)
2015/11/24 Pereira P. miRNA-29 bioseparation and target delivery strategies for Alzheimer’s disease. 3 minutos, 1 slide, a tua Tese! - Semana para a Ciência e Tecnologia
Universidade da Beira Interior (Covilhã, Portugal)
2015/07/06 Carvalho J, Ferreira J, Pereira P, Coutinho E, Sousa F, Cabrita E, Queiroz JA, Cruz C. Biosynthesis of a G-quadruplex-forming sequence and its stabilization by naphthalene-based ligands. X Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2015/07/06 Santos TA, Pereira P, Sousa F, Queiroz JA, Cruz C. Production and purification of DNA G-quadruplex using pPH600 plasmid. X Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2015/07/06 Pereira P, Pedro AQ, Tomás J, Cruz C, Sousa Â, Maia C, Queiroz JA, Figueiras A, Sousa F. Biosynthesis, purification and brain-targeted delivery of pre-miR-29b biopharmaceuticals for Alzheimer’s disease therapy. X Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2015/05/06 Pereira P. Pre-miR-29b biopharmaceutical for Alzheimer’s disease therapy: biosynthesis, purification and targeted delivery. (Invited) III Jornadas de Química e Bioquímica
(Covilhã, Portugal)
2015/04/17 Almeida AM, Pereira P, Tomás J, Figueiredo V, Queiroz JA, Sousa F, Sousa Â. Supercoiled HPV16 E6/E7 plasmid DNA-based vaccine purified by affinity chromatography for in vitro transfection studies. VIII Conference of Technology and Health
Instituto Politécnico da Guarda (Guarda, Portugal)
2014/07/01 Almeida AM, Pereira P, Tomás J, Queiroz JA, Sousa F, Sousa Â. Optimized purification strategy of supercoiled HPV16 E6/E7 plasmid DNA-based vaccine for in vitro transfection studies. IX Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2014/07/01 Pereira P, Tomás J, Sousa Â, Queiroz JA, Figueiras A, Sousa F. Pre-miR-29 biosynthesis and purification for polyplexes-mediated delivery to in vitro Alzheimer’s disease model. IX Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2014/03/13 Pereira P. Pre-miR-29 bioseparation and target delivery strategies for Alzheimer’s disease. (Invited) V Jornadas Nacionais de Ciências Biomédicas
(Covilhã, Portugal)
2013/12/03 Pereira P, Sousa Â, Queiroz JA, Figueiras A, Sousa F. Pre-miR-29 purification by amino acids-affinity chromatography. 8th Portuguese National Meeting of Chromatography (8ENC)
Univerisiadade da Beira Interior (Covilhã, Portugal)
2013/07/01 Afonso A, Pereira P, Sousa Â, Sousa F. Pre-miR-29b-1 isolation using a new chromatographic strategy with tyrosine-agarose. VIII Annual CICS-UBI Symposium
CICS-UBI (Covilhã, Portugal)
2012/05/19 Pereira P. Development of new therapeutic strategies for miRNA delivery. (Invited) 1st Workshop on Pharmaceutical Technology - “New Drug Delivery Systems
Faculdade de Farmácia, Universidade de Coimbra (Coimbra, Portugal)
2011/07/05 Pereira P, Figueiras A, Sousa F. Development of new therapeutic strategies for siRNA delivery. VI Annual CICS Symposium
CICS-UBI (Covilhã, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/01/01 - 2024/12/15 Optimization of bioink formulations for peripheral nerve regeneration
Co-supervisor
 Integrated Master's Degree in Micro and Nanotechnology Engineering (Master)
Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
2023/09/01 - 2024/09/28 Combatendo a Doença de Alzheimer usando copolímeros multivalentes
Supervisor
 Biomedical Engineering (Master)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2023/09/01 - 2024/09/12 3D Printing of wound dressing materials using a light-based technology
Co-supervisor
 Biomedical Engineering (Master)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2024/03/01 - 2024/06/28 Combater a doença de Alzheimer usando glicopolímeros
Supervisor
 Biotecnologia (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2024/03/01 - 2024/06/28 Desenvolvimento de um polímero com potencial terapêutico para o tratamento da doença de Alzheimer
Supervisor
 Biotecnologia (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2018 - 2019 Evaluation of the role of miR-9 and miR-29 in amyloid pathway of Alzheimer's disease
Co-supervisor of Micaela Sofia Ribeiro Riscado
Bioquímica (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2017 - 2018 Potencial terapêutico de miR-9 e miR-29 na doença de Alzheimer
Co-supervisor of Bruno Miguel Cameira Baptista
 Ciências Biomédicas (Master)
Universidade da Beira Interior, Portugal
2015 - 2016 miR-9 and miR-29 in Alzheimer's disease: assessment of a possible synergy
Co-supervisor of JOANA FILIPA SOARES RODRIGUES
 Ciências Biomédicas (Master)
Universidade da Beira Interior, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/02/21 - Current Seminar: Polymers, a Valence in the IPN Ecosystem (2024/02/21)
Seminar
 Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2023/11/28 - 2023/11/29 3DBIW - 3D Bioprinting Iberian Workshop (2023/11/28)
Workshop (Member of the Organising Committee)
 CELLINK AB, Sweden

Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal

Paralab - Equipamentos Industriais e de Laboratório SA, Portugal
2013/12/02 - 2013/12/04 8º Encontro Nacional de Cromatografia (2013/12/02 - 2013/12/04)
Congress (Member of the Organising Committee)
 Universidade da Beira Interior, Portugal
2013/07/01 - 2013/07/02 VIII Annual CICS-UBI Symposium (2013/07/01 - 2013/07/02)
Symposium (Member of the Organising Committee)
 Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/01/26 - Current Pharmaceutical Preformulation and Thermal Analysis.
Seminar
 NETZSCH-Gerateb¿u Webinar.
2022/11/11 - Current MOLDPLAS Batalha. Salão de máquinas, equipamentos, matérias-primas e tecnologia para moldes e plásticos. EXPOSALÃO – Batalha
Exhibition
2022/06/29 - Current On demand: DSC Performance at High Temperatures.
Seminar
 NETZSCH-Gerateb¿u Webinar
2022/06/07 - Current Thermal analysis - equipment Differential Scanning Calorimeter DSC 204 F1 Phoenix and Thermogravimetric Analyzer TGA 209 F1 Libra (NETZSCH): Advanced use in techniques; Adaptation and configuration of equipment to international standards; Clarification of doubts; Interpretation of results.
Workshop
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2022/06/07 - Current Diffusion techniques/thermal conductivity and its various applications.
Seminar
 NETZSCH-Gerateb¿u Webinar
2022/04/29 - Current UV module of DSC 204 F1 Phoenix Differential Calorimetry equipment (NETZSCH): Description and use of different accessories; UV module configuration and operation; Sample preparation and conducting an analysis; Interpretation of results
Workshop
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2021/03/30 - 2021/03/31 DSC 204 F1 Phoenix Differential Scanning Calorimetry equipment (NETZSCH): Theoretical Foundations of the Technique; Operation with the equipment and with the Autosampler; Preparation of Samples and performance of various types of Analysis; Training in Acquisition Software; Results Processing and Temperature and Sensitivity Calibration.
Workshop
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2021/03/23 - 2021/03/24 TG 209 F1 Thermogravimetric Analysis equipment (NETZSCH): Theoretical foundations of the technique; Operation with the equipment and with the autosampler; Sample preparation and analyses; Training in acquisition software, results treatment and temperature calibration and sensitivity; Interpretation of results.
Workshop
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2012/05/19 - 2012/05/21 1st Workshop on Pharmaceutical Technology
Workshop
Universidade de Coimbra Faculdade de Farmácia, Portugal
2011/11/26 - 2011/11/26 Seminar of Food security: legislation and certification
Seminar
Universidade da Beira Interior, Portugal
2011/09/22 - 2011/09/22 Workshop of GE Healthcare - Life Sciences: ÄKTA User Day. Hotel Praia-Mar (Carcavelos)
Workshop
GE Healthcare, United States
2011/05/18 - 2011/05/18 Protein Folding
Seminar
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2011/03/10 - 2011/03/12 I Jornadas Ibéricas de Toxicologia
Congress
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010/05/19 - 2010/05/19 Cristalização de Proteínas: Estrutura, Função, Raios X?
Seminar
Universidade da Beira Interior, Portugal
2010/04/28 - 2010/04/28 Das leveduras Às moléculas: novas ferramentas no estudo das doenças neurodegenrativas
Seminar
Universidade da Beira Interior, Portugal
2010/04/21 - 2010/04/23 2nd Portuguese Young Chemists Meeting - 2PYCheM
Congress
Universidade de Aveiro, Portugal
2010/03/03 - 2010/03/03 Divulgação e promoção da Técnica de Ressonância Magnética Nuclear (NMR) - 3 hours
Seminar
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010/02/24 - 2010/02/24 GE Solutions in Life Sciences Seminar
Seminar
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2009/05/15 - 2009/05/15 Neoplasias do Sistema Imunitário - Actividade Formativa Creditada pela Ordem dos Farmacêuticos
Workshop
Universidade da Beira Interior, Portugal
2009/04/18 - 2009/04/18 Seminário de Virologia
Seminar
Universidade da Beira Interior, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/05/24 Desenvolvimento de guias poliméricas de dextrano/e-caprolactona por impresssão 3D para aplicação em recuperação estrutural de nervos
(Thesis) Main arguer
 Inês Carolina Pires Escobar (Other)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2023/10/29 Influência da distribuição do peso molecular de copolímeros de bloco catiónicos no seu desempenho como vetores de entrega de material genético para tratamento do cancro
(Thesis) Main arguer
 Nuno Diogo Pargana Mateus (Master)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2023/07/28 Optimization of a pipeline for human induced pluripotent stem cells-derived neurons characterization after exposure to fossil-based and bio-based plastic additives
(Thesis) Main arguer
 André Soares Pinto (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2020/01/25 Chromatographic bioseparation of interferon alfa-2b using ionic-liquid-functionalized silicas
(Thesis) Main arguer
 Guilherme Lobo e Sousa (Master)
Universidade de Aveiro Departamento de Química, Portugal
2020 Design and controlled synthesis of glycopolymers under biologically relevant conditions: from sugar-based monomers to complex polymeric strcutures. Examiner of PhD thesis project preparation. Jéssica Patrícia Melo Ribeiro (PhD)
Universidade de Coimbra Departamento de Engenharia Quimica, Portugal
2018 Production and Purification of pre-miRNA-149 with potential application in diagnosis of prostate cancer
(Thesis) Main arguer
 Henrique Samuel Ramos Martins (Master)
Universidade da Beira Interior, Portugal
2017/11/03 Recuperação de microRNA através de Partículas Magnéticas
(Thesis) Main arguer
 Joana Margarida Teixeira Pinto (Master)
Universidade da Beira Interior, Portugal
2015 Desenvolvimento de um processo biotecnológico para a preparação de long non-coding RNAs com aplicação terapêutica
(Thesis) Main arguer
 Mário Almeida (Other)
Universidade da Beira Interior Faculdade de Ciências, Portugal
2015 Obtenção de um microRNA para o tratamento do cancro do colo do útero
(Thesis) Main arguer
 Ana Abreu (Other)
Universidade da Beira Interior Faculdade de Ciências, Portugal
2015 Sistemas de entrega de um vetor multigénico de DNA plasmídico para o tratamento do cancro do colo do útero
(Thesis) Arguer
 Mafalda Cautela (Other)
Universidade da Beira Interior Faculdade de Ciências, Portugal
2015 Potencial terapêutico do microRNA-29 em diferentes patologias
(Thesis) Main arguer
 Vanda Taborda (Other)
Universidade da Beira Interior Faculdade de Ciências, Portugal
2014 Preparação e purificação de um oligonucleótido anti-sense para silenciamento do microRNA 106: uma nova abordagem na prevenção do cancro Colo-rectal
(Thesis) Main arguer
 Ana Rita Quelhas (Other)
Universidade da Beira Interior Faculdade de Ciências, Portugal

Association member

Society Organization name Role
2012 - Current Sociedade Portuguesa de Química

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2016 - 2018 Seminars in Biotechnology (Invited speaker - 4 hours) Bioquímica (Mestrado integrado) Universidade da Beira Interior, Portugal
2016 - 2018 Seminars in Biotechnology (Invited speaker - 4 hours) Química Medicinal (Mestrado integrado) Universidade da Beira Interior, Portugal
2016 - 2018 Seminars in Biotechnology (Invited speaker - 4 hours) Biotecnologia (Mestrado integrado) Universidade da Beira Interior, Portugal
2016 - 2018 Seminars in Biotechnology (Invited speaker - 4 hours) Biotecnologia (Mestrado integrado) Universidade da Beira Interior, Portugal
2014 - 2016 Pharmaceutical Biotechnology (Theoretical-practical classes - 4 hours) Ciências Farmacêuticas (Mestrado integrado) Universidade da Beira Interior, Portugal
2014 - 2016 Pharmaceutical Biotechnology (Theoretical-practical classes - 4 hours) Biotecnologia Universidade da Beira Interior, Portugal
2012 - 2016 Structure and Function of Proteins (Theoretical-practical classes - 2 hours) Bioquímica (Mestrado integrado) Universidade da Beira Interior, Portugal
2012 - 2016 Structure and Function of Proteins (Theoretical-practical classes - 2 hours) Química Medicinal (Mestrado integrado) Universidade da Beira Interior, Portugal
2012 - 2016 Structure and Function of Proteins (Theoretical-practical classes - 2 hours) Biotecnologia (Mestrado integrado) Universidade da Beira Interior, Portugal
2012 - 2016 Microbiology (Practical classes - 30 hours) Bioquímica (Licenciatura) Universidade da Beira Interior, Portugal
2012 - 2016 Analytical Methods (Practical classes - 2 hours) Bioquímica (Licenciatura) Universidade da Beira Interior, Portugal
2012 - 2016 Analytical Methods (Practical classes - 2 hours) Ciências Farmacêuticas (Mestrado integrado) Universidade da Beira Interior, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2022 - Current Biosensors (2079-6374) MDPI
2022 - Current Polymers (2073-4360) MDPI
2022 - Current Life (2075-1729) MDPI
2021/05 - Current Electronic Journal of Biotechnology Elsevier
2021/05 - Current Marine drugs (1660-3397) MDPI
2021 - Current Cancers (2072-6694) MDPI
2021 - Current Cells (2073-4409) MDPI
2021 - Current International Journal of Environmental Research and Public Health (1660-4601) MDPI
2021 - Current Antioxidants (2076-3921) MDPI
2021 - Current Molecules (1420-3049) MDPI
2021 - Current Pharmaceuticals (1424-8247) MDPI
2021 - Current Sensors (1424-8220) MDPI
2021 - Current Journal of Personalized Medicine (2075-4426) MDPI
2019 - Current Molecular Immunology (0161-5890) Elsevier
2018 - Current Applied Microbiology and Biotechnology (1432-0614) Springer-Verlag
2018 - Current Biomedicine & Pharmacotherapy (0753-3322) Elsevier

Mentoring / Tutoring

Topic Student name
2016 - 2017 New strategies for RNAs purification using ionic liquids João Martins
2016 - 2017 Pre-miR-29 as a lung cancer biopharmaceutical: a new approach for its purification and delivery with functionalized nanoparticles Maria Barreira
2014 - 2015 Development of new methodologies for minicircular DNA purification using monolithic supports Tatiana Diamantino
2014 - 2015 Production and Purification of DNA G-quadruplex using pPH600 plasmid Tiago Santos
2014 - 2015 Biosynthesis of a G-Quadruplex-forming sequence and its stabilization by ligands Josué Carvalho
2012 - 2013 Development and optimization of a microRNA purification technology by affinity chromatography, using the concept of QbD. Adriana Afonso
Distinctions

Award

2023 1st place in the Innovation category of the 11th Edition of the business ideas contest ARRISCA C
2023 Coimbra City Council Award
Câmara Municipal de Coimbra, Portugal
2022 2022 Innovation Award of the University of Coimbra - Prémio de Inovação J. Norberto Pires
Universidade de Coimbra, Portugal
2019 Best Short Talk Award in the XIV Annual CICS-UBI Symposium: Carapito R, Neves M, Pereira P, Pedro A, Queiroz JA, Freire MG, Sousa F. Ionic liquids-based supports for the purification of RNA.
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2017 Best Join Paper 2016 in the XII Annual CICS-UBI Symposium: Recombinant pre-miR-29b for Alzheimer´s disease therapeutics.
NZYTech Lda, Portugal

Laborspirit, Lda, Portugal
2015 Best Oral Communication Award in the X Annual CICS-UBI Symposium: Pereira P, Pedro AQ, Tomás J, Cruz C, Sousa A, Maia C, Queiroz JA, Figueiras AR, Sousa F. Biosynthesis, purification and brain-targeted delivery of pre-miR-29b biopharmaceuticals for AD.
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2014 Best Short Talk Award in the IX Annual CICS-UBI Symposium: Almeida AM, Pereira P, Tomás J, Queiroz JA, Sousa F, Sousa Â. Optimized purification strategy of supercoiled HPV16 E6/E7 plasmid DNA-based vaccine for in vitro transfection studies.
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2011 Best Short Oral Communication Award in the VI Annual CICS-UBI Symposium: Pereira P, Figueiras A, Sousa F. Development of new therapeutic strategies for siRNA delivery.
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal