???global.info.a_carregar???
Miglena Georgieva.
Identification

Personal identification

Full name
Miglena Georgieva

Citation names

  • Georgieva, Miglena
  • Miglena K. Georgieva
  • Georgieva, M. K.

Author identifiers

Ciência ID
4617-742F-6EB7

Email addresses

  • miggeo@gmail.com (Personal)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Bulgarian (Mother tongue)
English
Portuguese
Russian Upper intermediate (B2) Advanced (C1) Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2005/07/01
Concluded
 Organic chemistry (Doktor (PhD))
Institut po organicna himia s Cent'r po fitohimia B'lgarska akademia na naukite, Bulgaria
"IR spectral and structural changes, caused by the conversion of nitrile molecules into anions and radicals" (THESIS/DISSERTATION)
1994/10/01 - 1999/07/31
Concluded
 organic and analytical chemistry (Magister)
University of Sofia - Department of Chemistry, Bulgaria
Affiliation

Science

Category
Host institution 		Employer
2018/12/19 - Current Researcher (Research) Universidade Nova de Lisboa Departamento de Química, Portugal
Projects

Grant

Designation Funders
2015/12/01 - 2018/11/30 Asymmetric organocatalyzed domino reactions with alfa,beta-unsaturated carbonyl compounds. A theoretical study.
SFRH / BPD / 104323 / 2014
Post-doc Fellow
Concluded
2006/09/01 - 2013/11/30 Stereoselective free radical reactions. A theoretical approach
SFRH / BPD / 22179 / 2005
Post-doc Fellow
Concluded

Contract

Designation Funders
2019/01/01 - 2019/12/31 Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
UID/QUI/50006/2019
LA/P/0008/2020
10.54499/LA/P/0008/2020
Universidade do Porto Faculdade de Ciências, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade Nova de Lisboa, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Aveiro, Portugal

Universidade de Évora, Portugal

Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal

Universidade de Lisboa Instituto Dom Luiz, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 6 - 2011-2012
PEst-C/EQB/LA0006/2011
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2019 - Current Development of novel benzimidazoles with combined antioxidant and antineoplastic activity
¿¿-06-¿39/4
consultant
Ongoing
2020/03/04 - 2020/07/02 DFT study of radical scavenging mechanisms and characterization of the reaction intermediates of new benzimidazole derivatives
Student Mobility for Traineeships Erasmus+
Supervisor
Concluded
Outputs

Publications

Conference poster
  1. Miglena K. Georgieva; Argirova, Maria; Petko Denev; Hristova-Avakumova, Nadya; Yancheva, Denitsa Y.. Corresponding author: Miglena K. Georgieva. "Quantum-chemical study on radical scavenging properties of 1H-benzimidazol-2-yl hydrazones with hydroxyphenyl and methoxyphenyl moieties with promising anthelminthic, antiproliferative and antioxidant activity". Paper presented in 9th EuChemS Chemistry Congress, 2024.
  2. Rippel, Rafael; Leitão, Flávia; Georgieva, Miglena; Lourenço, Ana; Ferreira, Luísa Maria ; Branco, Paula S.. Corresponding author: Rippel, Rafael. "An unexpected loss of chirality: Challenges in the synthesis of an aminopyrrolidine core". Paper presented in 8th EuChemS Chemistry Congress (ECC8), 2022.
  3. E. Cherneva; M. Argirova; G. Momekov; R. Mihaylova; M. Georgieva; D. Yancheva. "PREPARATION OF COPPER COMPLEXES FROM BENZIMIDAZOLE-2-YL HYDRAZONES CONTAINING SALICYLIC MOIETY AND CYTOTOXICITY STUDY". Paper presented in 8th EuChemS Chemistry Congress (ECC8), 2022.
  4. Argirova, Maria; Miglena K. Georgieva; Hristova-Avakumova, Nadya; Vuchev, Dimitar I.; Anichina, Kameliya K.; Yancheva, Denitsa Y.. "New 5(6)-methyl-1H-benzimidazol-2-yl hydrazones: synthesis, combined evaluation of the anthelminthic and antioxidant activity and performed quantum-chemical calculations". Paper presented in 8th EuChemS Chemistry Congress (ECC8), 2022.
  5. Georgieva, Miglena K.; Argirova, Maria; Hristova-Avakumova, Nadya; Yancheva, Denitsa Y.. Corresponding author: Georgieva, Miglena K.. "A theoretical inside on the mechanism of antioxidant activity of newly synthesized 1H-benzimidazole-2-yl hydrazones". Paper presented in 14th National Organic chemistry meeting, 2022.
Journal article
  1. Rippel, Rafael; Leitão, Flávia; Georgieva, Miglena K.; Mamede, Rafael; Gomes, Clara S. B.; Roma-Rodrigues, Catarina; Fernandes, Alexandra R.; et al. "Exploring the synthesis of aminal guanidine-based molecules: synthesis of cernumidine and analogues, and survey of its anti-inflammatory activity". New Journal of Chemistry 48 12 (2024): 5247-5257. http://dx.doi.org/10.1039/d3nj05406c.
    Published • 10.1039/d3nj05406c
  2. Georgieva, Miglena K.; Anastassova, Neda; Stefanova, Denitsa; Yancheva, Denitsa. "Radical Scavenging Mechanisms of 1-Arylhydrazone Benzimidazole Hybrids with Neuroprotective Activity". The Journal of Physical Chemistry B 127 20 (2023): 4364-4373. http://dx.doi.org/10.1021/acs.jpcb.2c05784.
    Published • 10.1021/acs.jpcb.2c05784
  3. Georgieva, Miglena K.; Santos, A. Gil. "Theoretical Study on Chiral Boron Complex-Promoted Asymmetric Diels-Alder Cycloadditions". European Journal of Organic Chemistry 2022 45 (2022): http://dx.doi.org/10.1002/ejoc.202201082.
    Published • 10.1002/ejoc.202201082
  4. Argirova, Maria A.; Georgieva, Miglena K.; Hristova-Avakumova, Nadya G.; Vuchev, Dimitar I.; Popova-Daskalova, Galya V.; Anichina, Kameliya K.; Yancheva, Denitsa Y.. Corresponding author: Yancheva, Denitsa Y.. "New 1H-benzimidazole-2-yl hydrazones with combined antiparasitic and antioxidant activity". RSC Advances 11 63 (2021): 39848-39868. http://dx.doi.org/10.1039/d1ra07419a.
    Published • 10.1039/d1ra07419a
  5. Georgieva, Miglena K.; Duarte, Filipe J. S.; Santos, A. Gil. "Directed electrostatic activation in enantioselective organocatalytic cyclopropanation reactions: a computational study". Organic & Biomolecular Chemistry 14 25 (2016): 5965-5982. http://dx.doi.org/10.1039/c6ob00748a.
    10.1039/c6ob00748a
  6. Georgieva, Miglena K.; Santos, A. Gil. "A Computational Study on Lewis Acid-Catalyzed Diastereoselective Acyclic Radical Allylation Reactions with Unusual Selectivity Dependence on Temperature and Epimer Precursor". The Journal of Organic Chemistry 79 23 (2014): 11483-11495. http://dx.doi.org/10.1021/jo502102s.
    10.1021/jo502102s
  7. Georgieva, Miglena K.; Duarte, Filipe J. S.; Queirós, Margarida V. B.; Santos, A. Gil. "Catalytic Asymmetric 5-enolexo Aldolizations. A Computational Study". The Journal of Organic Chemistry 77 13 (2012): 5569-5576. http://dx.doi.org/10.1021/jo300633y.
    10.1021/jo300633y
  8. Georgieva, Miglena K.; Duarte, Filipe J. S.; Bakalova, Snezhana M.; Santos, A. Gil. "2,5-Disubstituted Pyrrolidines as Chiral Auxiliaries in Radical Reactions: A Theoretical Approach". European Journal of Organic Chemistry 2010 25 (2010): 4841-4850. http://dx.doi.org/10.1002/ejoc.201000479.
    10.1002/ejoc.201000479
  9. Emel’yanenko, V. N.; Verevkin, S. P.; Schick, C.; Stepurko, E. N.; Roganov, G. N.; Georgieva, M. K.. "The thermodynamic properties of S-lactic acid". Russian Journal of Physical Chemistry A 84 9 (2010): 1491-1497. http://dx.doi.org/10.1134/s0036024410090074.
    10.1134/s0036024410090074
  10. Emel’yanenko, V. N.; Verevkin, S. P.; Stepurko, E. N.; Roganov, G. N.; Georgieva, M. K.. "Thermodynamic properties of glycolic acid and glycolide". Russian Journal of Physical Chemistry A 84 8 (2010): 1301-1308. http://dx.doi.org/10.1134/s0036024410080054.
    10.1134/s0036024410080054
  11. Emel’yanenko, V. N.; Verevkin, S. P.; Stepurko, E. N.; Roganov, G. N.; Georgieva, M. K.. "Thermodynamical properties of e-caprolactone". Russian Journal of Physical Chemistry A 84 3 (2010): 356-363. http://dx.doi.org/10.1134/s0036024410030039.
    10.1134/s0036024410030039
  12. Bakalova, Snezhana M.; Duarte, Filipe J. S.; Georgieva, Miglena K.; Cabrita, Eurico J.; Santos, A. Gil. "An Alternative Mechanism for Diels-Alder Reactions of Evans Auxiliary Derivatives". Chemistry - A European Journal 15 31 (2009): 7665-7677. http://dx.doi.org/10.1002/chem.200900628.
    10.1002/chem.200900628
  13. Emel’yanenko, V. N.; Verevkin, S. P.; Burakova, E. N.; Roganov, G. N.; Georgieva, M. K.. "The thermodynamic properties of alkylated ¿-lactones". Russian Journal of Physical Chemistry A 83 4 (2009): 598-603. http://dx.doi.org/10.1134/s0036024409040141.
    10.1134/s0036024409040141
  14. Emel’yanenko, V. N.; Verevkin, S. P.; Burakova, E. N.; Roganov, G. N.; Georgieva, M. K.. "The thermodynamic properties of delta-lactones". Russian Journal of Physical Chemistry A 83 8 (2009): 1271-1279. http://dx.doi.org/10.1134/s0036024409080056.
    10.1134/s0036024409080056
  15. Emel’yanenko, V. N.; Verevkin, S. P.; Burakova, E. N.; Roganov, G. N.; Georgieva, M. K.. "The thermodynamic properties of 4-pentenoic acid". Russian Journal of Physical Chemistry A 82 9 (2008): 1521-1526. http://dx.doi.org/10.1134/s0036024408090215.
    10.1134/s0036024408090215
  16. Kozlova, Svetlana A.; Emel’yanenko, Vladimir N.; Georgieva, Miglena; Verevkin, Sergey P.; Chernyak, Yury; Schäffner, Benjamin; Börner, Armin. "Vapour pressure and enthalpy of vaporization of aliphatic dialkyl carbonates". The Journal of Chemical Thermodynamics 40 7 (2008): 1136-1140. http://dx.doi.org/10.1016/j.jct.2008.02.012.
    10.1016/j.jct.2008.02.012
  17. Verevkin, Sergey P.; Georgieva, Miglena; Melkhanova, Svetlana V.. "Vapor Pressures and Phase Transitions of a Series of the Aminonaphthalenes". Journal of Chemical & Engineering Data 52 1 (2007): 286-290. http://dx.doi.org/10.1021/je060394v.
    10.1021/je060394v
  18. Popova, Angelina D.; Georgieva, Miglena. K.; Petrov, Ognyan. I.; Petrova, Katya. V.; Velcheva, Evelina. A.. "IR spectral and structural studies of 4-aminobenzenesulfonamide (sulfanilamide)-d0, -d4, and -15N, as well as their azanions: Combined DFT B3LYP/experimental approach". International Journal of Quantum Chemistry 107 8 (2007): 1752-1764. http://dx.doi.org/10.1002/qua.21242.
    10.1002/qua.21242
  19. Georgieva, Miglena K.; Velcheva, Evelina A.. "Computational and experimental studies on the IR spectra and structure of the simplest nitriles (C1 and C2), their anions, and radicals". International Journal of Quantum Chemistry 106 6 (2006): 1316-1322. http://dx.doi.org/10.1002/qua.20887.
    10.1002/qua.20887
  20. Georgieva, Miglena K.; Binev, Ivan G.. "The computational study on the structural and force field changes, caused by the conversion of dicyanamide into the azanion". Journal of Molecular Structure 752 1-3 (2005): 14-19. http://dx.doi.org/10.1016/j.molstruc.2005.05.014.
    10.1016/j.molstruc.2005.05.014
  21. Binev, Yuri I.; Georgieva, Miglena K.; Daskalova, Lalka I.. "Spectrochemical, ab initio and density functional studies on the conversion of 2-hydroxybenzonitrile (o-cyanophenol) into the oxyanion". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 60 11 (2004): 2601-2610. http://dx.doi.org/10.1016/j.saa.2003.12.040.
    10.1016/j.saa.2003.12.040
  22. Georgieva, Miglena K.; Angelova, Polina N.; Binev, Ivan G.. "The conversion of 3- and 4-hydroxybenzonitriles (m- and p-cyanophenols) into oxyanions, followed by IR spectra, ab initio and density functional calculations". Journal of Molecular Structure 692 1-3 (2004): 23-35. http://dx.doi.org/10.1016/j.molstruc.2003.12.022.
    10.1016/j.molstruc.2003.12.022
  23. Georgieva, Miglena K.. "Ab initio and density functional force field studies on the IR spectra and structure of diazonium dicyanomethylide (diazodicyanomethane)". Journal of Molecular Structure 691 1-3 (2004): 71-77. http://dx.doi.org/10.1016/j.molstruc.2003.11.023.
    10.1016/j.molstruc.2003.11.023
  24. Binev, Yuri I; Georgieva, Miglena K; Novkova, Snezhana I. "The conversion of phenylpropanedinitrile (phenylmalononitrile) into the carbanion, followed by IR spectra, ab initio and DFT force field calculations". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 59 13 (2003): 3041-3052. http://dx.doi.org/10.1016/s1386-1425(03)00118-5.
    10.1016/s1386-1425(03)00118-5
  25. Novkova, S.I.; Georgieva, M.K.; Binev, Y.I.; Petkov, Ch.Ts.; Binev, I.G.. "The formation and isomerization of 3-amino-2-butenenitrile (diacetonitrile) and its anion, followed by IR spectra, ab initio and DFT force field calculations". Journal of Molecular Structure: THEOCHEM 636 1-3 (2003): 167-183. http://dx.doi.org/10.1016/s0166-1280(03)00510-4.
    10.1016/s0166-1280(03)00510-4
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/09/01 - 2024/11/29 Synthetic approaches and computational studies of naturally occurring phenolic carbohydrate esters as lead pharmaceutics
Co-supervisor
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/01/23 - 2023/06/30 Synthetic Approaches and Computational Modeling of Naturally Occurring Phenolic Carbohydrate Esters as Lead Pharmaceutics
Co-supervisor

Ad Hoc journal article review

Journal title (ISSN) Publisher
2023/12/02 - 2023/12/25 Theoretical Chemistry Accounts Springer Nature