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Ana Rita Grosso gathered a Biology degree (FCUL, 2002), followed by a MSc in Bioinformatics (FCUL-IGC, 2006). Her multi-omics expertise in biomedical research was accomplished by gathering a PhD in Biomedical Sciences, under supervision of Simon Tavaré (Cambridge Univ., UK) and Maria Carmo-Fonseca (IMM/FMUL). Her PhD research unveiled the existence of splicing-factors expression signatures responsible by the tissue-specific regulation of alternative splicing. After obtaining the PhD in 2010, she did a first PostDoc with Maria Carmo-Fonseca (IMM/FMUL), followed by a second PostDoc with Sergio de Almeida (IMM/FMUL). Her PostDoc research disclosed new mechanisms of splicing and transcription dynamics. ____________________________________________________________________________________________________________________________________________ Since 2014, Ana Rita has started her own research line where she identified chromatin alterations that interfere with transcriptional fidelity in cancer. In 2018, Ana Rita Grosso moved to UCIBIO/FCT-NOVA to foster her scientific independence and consolidate her research group. Since then she obtained 1 Individual Salary Grant and 1 Project Grant, with which she could establish her current research group, composed of: 1 Senior Researcher, 1 PostDoc, 2 PhD-students, 1 junior Bioinformatician and 1 MSc Student. In parallel, she has also stablished collaborations with different research groups to decipher transcriptomic/epigenomic alterations underlying a wide range of diseases. Her main mission is to decipher pathological conditions using multi-omics approaches, identifying molecular events to be further used as biomarkers and therapeutic targets. ____________________________________________________________________________________________________________________________________________ Additionally, Ana Rita Grosso has been teaching specialized MSc courses in Genomics and Computational Biology fields, namely: “Computational Biology in Biomedicine” for the MSc in Bioinformatics and Computational Biology from (FCUL, 2012-2015); “Bioinformatics” for the MSc in Oncobiology (FMUL, 2014-2016); “Molecular Genomics and Evolution” and “Bioinformatics in Biomedicine” for the MSc in Molecular Genetics and Biomedicine (FCT-NOVA, 2018-onwards). ____________________________________________________________________________________________________________________________________________ To date, Ana Rita Grosso published 34 papers (1308 citations, h-index 18, avg-citations/paper 38.5). Also, she won in highly competitive schemes: 4 Salary Grants (PhD and PostDoc Fellowships, 2 Research Contracts); 6 Projects Grants (2 as PI, 1 as Co-PI and 3 as Researcher Core CV) as well as 2 Pfizer Awards for Basic Research. ____________________________________________________________________________________________________________________________________________
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Identification

Personal identification

Full name
Ana Rita Grosso

Citation names

  • Grosso, Ana Rita

Author identifiers

Ciência ID
3D18-571E-133A
ORCID iD
0000-0001-6974-4209
Researcher Id
I-6656-2013
Scopus Author Id
26639262500

Email addresses

  • argrosso@fct.unl.pt (Professional)

Addresses

  • Faculdade de Ciências e Tecnologia - Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Caparica, Almada, Portugal (Professional)

Websites

  • https://comics.dcv.fct.unl.pt (Professional)

Knowledge fields

  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2010
Concluded
 Ciências Biomedicas (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
"New insights into alternative splicing using microarray technology " (THESIS/DISSERTATION)
 Distinção e Louvor por unanimidade
2006
Concluded
 Bioinformatica (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Statistical Methodologies for the Analysis of DNA Microarray Data" (THESIS/DISSERTATION)
 Muito Bom
2002
Concluded
 Biologia (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"“Estudo Filogenético de Populações Europeias de Columba palumbus (Pombo-Torcaz), Recorrendo à Análise de DNA Mitocondrial”" (THESIS/DISSERTATION)
 15
Affiliation

Science

2018/01/01 - Current Auxiliary Researcher (Research)
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/01/01 - 2017/12/31 Auxiliary Researcher (Research)
Instituto de Medicina Molecular, Portugal
2010/03/01 - 2014/12/31 Postdoc (Research)
Instituto de Medicina Molecular, Portugal
2002/10/01 - 2005/12/31 Researcher (Research)
Universidade de Lisboa Faculdade de Ciências, Portugal
Projects

Grant

Designation Funders
2018 - 2021/09/30 Targeting Intra-Tumor heterogeneity as a promising therapeutic strategy for cancer
PTDC/MED-ONC/28660/2017
Principal investigator
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
2015 - 2019/12/01 Decoding pseudogene transcriptional regulation during cell differentiation
IF/00510/2014
Principal investigator
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
2016 - 2018/12 Novel tumorigenic mechanisms of aberrant epigenetic regulation in clear cell renal cell carcinoma
Provided by PTCRIS: 138597
 Fundação para a Ciência e a Tecnologia, I.P.
2015 - 2018/11 Long non-coding RNAs as new diagnostic biomarkers for African Sleeping sickness.
Provided by PTCRIS: 145744
 Fundação para a Ciência e a Tecnologia, I.P.
2013 - 2015/11 SETD2 mediates a novel tumor suppressor mechanism that is misregulated in clear cell renal carcinoma
Provided by PTCRIS: 124736
 Fundação para a Ciência e a Tecnologia, I.P.
2011 - 2014/01 Splicing-coupled mechanisms of chromatin remodeling and their global role in transcription
Provided by PTCRIS: 111451
 Fundação para a Ciência e a Tecnologia, I.P.
2011 - 2013/12 The role of RNA polymerase II in splicing regulation
Provided by PTCRIS: 113440
 Fundação para a Ciência e a Tecnologia, I.P.
2007 - 2010/08 Mechanisms of splicing regulation by U2AF proteins
Provided by PTCRIS: 69739
 Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Book chapter
  1. Grosso, Ana Rita; Carmo-Fonseca, Maria. 2013. "The Potential of Targeting Splicing for Cancer Therapy". In Nuclear Signaling Pathways and Targeting Transcription in Cancer, 313-336. Springer New York. http://dx.doi.org/10.1007/978-1-4614-8039-6_13.
    Published • 10.1007/978-1-4614-8039-6_13
Journal article
  1. Prudêncio, Pedro; Rebelo, Kenny; Grosso, Ana Rita; Martinho, Rui Gonçalo; Carmo-Fonseca, Maria. 2019. "Analysis of Mammalian Native Elongating Transcript sequencing (mNET-seq) high-throughput data". Methods. http://dx.doi.org/10.1016/j.ymeth.2019.09.003.
    10.1016/j.ymeth.2019.09.003
  2. Cunha, M.; Martins, C.; Grosso, A.R.; Costa, P.M.. 2019. "Mytilus galloprovincialis CYP1A-like mRNAs reveal closer proximity of mytilid CYP1A to the eumetazoan CYP2 family". Aquatic Toxicology 214: 105260. http://dx.doi.org/10.1016/j.aquatox.2019.105260.
    Published • 10.1016/j.aquatox.2019.105260
  3. de Matos, Mafalda; Posa, Ioana; Carvalho, Filipa; Morais, Vanessa; Grosso, Ana; de Almeida, Sérgio. 2019. "A Systematic Pan-Cancer Analysis of Genetic Heterogeneity Reveals Associations with Epigenetic Modifiers". Cancers 11 (3): 391. http://dx.doi.org/10.3390/cancers11030391.
    Published • 10.3390/cancers11030391
  4. Vítor, Alexandra C.; Sridhara, Sreerama C.; Sabino, João C.; Afonso, Ana I.; Grosso, Ana R.; Martin, Robert M.; de Almeida, Sérgio F.. 2019. "Single-molecule imaging of transcription at damaged chromatin". Science Advances 5 (1): eaau1249. http://dx.doi.org/10.1126/sciadv.aau1249.
    10.1126/sciadv.aau1249
  5. Nojima, Takayuki; Rebelo, Kenny; Gomes, Tomas; Grosso, Ana Rita; Proudfoot, Nicholas J.; Carmo-Fonseca, Maria. 2018. "RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing". Molecular Cell 72 (2): 369-+. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000447630200017&KeyUID=WOS:000447630200017.
    10.1016/j.molcel.2018.09.004
  6. Mancio-Silva, Liliana; Slavic, Ksenija; Grilo Ruivo, Margarida T.; Grosso, Ana Rita; Modrzynska, Katarzyna K.; Vera, Iset Medina; Sales-Dias, Joana; et al. 2017. "Nutrient sensing modulates malaria parasite virulence". Nature 547 (7662): 213-216. http://dx.doi.org/10.1038/nature23009.
    10.1038/nature23009
  7. Grosso, Ana Rita. 2017. "Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability.". Molecular cell. http://europepmc.org/abstract/med/28757210.
    10.1016/j.molcel.2017.07.002
  8. Sridhara, Sreerama Chaitanya; Carvalho, Sílvia; Grosso, Ana Rita; Gallego-Paez, Lina Marcela; Carmo-Fonseca, Maria; de Almeida, Sérgio Fernandes. 2017. "Transcription Dynamics Prevent RNA-Mediated Genomic Instability through SRPK2-Dependent DDX23 Phosphorylation". Cell Reports 18 (2): 334-343. http://dx.doi.org/10.1016/j.celrep.2016.12.050.
    10.1016/j.celrep.2016.12.050
  9. Machado, Miguel P.; Matos, Isa; Grosso, Ana R.; Schartl, Manfred; Coelho, Maria M.. 2016. "Non-canonical expression patterns and evolutionary rates of sex-biased genes in a seasonal fish". Molecular Reproduction and Development 83 (12): 1102-1115. http://dx.doi.org/10.1002/mrd.22752.
    10.1002/mrd.22752
  10. Posa, Ioana; Carvalho, Silvia; Tavares, Joana; Grosso, Ana Rita. 2016. "A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma". Oncotarget 7 (30). http://dx.doi.org/10.18632/oncotarget.9487.
    10.18632/oncotarget.9487
  11. Muñoz-Ruiz, Miguel; Ribot, Julie C; Grosso, Ana R; Gonçalves-Sousa, Natacha; Pamplona, Ana; Pennington, Daniel J; Regueiro, José R; Fernández-Malavé, Edgar; Silva-Santos, Bruno. 2016. "TCR signal strength controls thymic differentiation of discrete proinflammatory ¿d T cell subsets". Nature Immunology 17 (6): 721-727. http://dx.doi.org/10.1038/ni.3424.
    10.1038/ni.3424
  12. Jesus, T.F.; Grosso, A.R.; Almeida-Val, V.M.F.; Coelho, M.M.. 2016. "Transcriptome profiling of two Iberian freshwater fish exposed to thermal stress". Journal of Thermal Biology 55: 54-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951081833&partnerID=MN8TOARS.
    10.1016/j.jtherbio.2015.11.009
  13. Grosso, Ana R; Leite, Ana P; Carvalho, Sílvia; Matos, Mafalda R; Martins, Filipa B; Vítor, Alexandra C; Desterro, Joana MP; Carmo-Fonseca, Maria; de Almeida, Sérgio F. 2015. "Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma". eLife 4. http://dx.doi.org/10.7554/elife.09214.
    10.7554/elife.09214
  14. Álvarez, P.; Arthofer, Wolfgang; Coelho, Maria M.; Conklin, D.; Estonba, A.; Grosso, Ana R.; Helyar, S. J.; et al. 2015. "Genomic Resources Notes Accepted 1 June 2015 - 31 July 2015". Molecular Ecology Resources 15 (6): 1510-1512. http://dx.doi.org/10.1111/1755-0998.12454.
    10.1111/1755-0998.12454
  15. Almeida-Val, Vera Maria Fonseca; Boscari, E.; Coelho, Maria Manuela; Congiu, L.; Grapputo, A.; Grosso, Ana Rita; Jesus, Tiago Filipe; et al. 2015. "Genomic Resources Notes accepted 1 April 2015 - 31 May 2015". Molecular Ecology Resources 15 (5): 1256-1257. http://dx.doi.org/10.1111/1755-0998.12439.
    10.1111/1755-0998.12439
  16. Veigas, Bruno; Pedrosa, Pedro; Carlos, Fábio F; Mancio-Silva, Liliana; Grosso, Ana Rita; Fortunato, Elvira; Mota, Maria M; Baptista, Pedro V. 2015. "One nanoprobe, two pathogens: gold nanoprobes multiplexing for point-of-care". Journal of Nanobiotechnology 13 (1). http://dx.doi.org/10.1186/s12951-015-0109-1.
    10.1186/s12951-015-0109-1
  17. Nojima, Takayuki; Gomes, Tomás; Grosso, Ana Rita Fialho; Kimura, Hiroshi; Dye, Michael J.; Dhir, Somdutta; Carmo-Fonseca, Maria; Proudfoot, Nicholas J.. 2015. "Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing". Cell 161 (3): 526-540. http://dx.doi.org/10.1016/j.cell.2015.03.027.
    10.1016/j.cell.2015.03.027
  18. Grosso, A.R.; Leite, A.P.; Carvalho, S.; Matos, M.R.; Martins, F.B.; Vítor, A.C.; Desterro, J.M.P.; Carmo-Fonseca, M.; de Almeida, S.F.. 2015. "Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma". eLife 4 (NOVEMBER20). http://www.scopus.com/inward/record.url?eid=2-s2.0-84958191482&partnerID=MN8TOARS.
    10.7554/eLife.09214
  19. Dourado, C.G.; Duarte, M.A.; Grosso, A.R.; Bastos-Silveira, C.; Marrero, P.; Oliveira, P.; Paulo, O.S.; Dias, D.. 2014. "Phylogenetic origin of the endemic pigeons from Madeira (Columba trocaz) and Azores Islands (Columba palumbus azorica)". Journal of Ornithology 155 (1): 71-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891629909&partnerID=MN8TOARS.
    10.1007/s10336-013-0988-6
  20. Lança, T.; Costa, M.F.; Gonca¸lves-Sousa, N.; Rei, M.; Grosso, A.R.; Penido, C.; Silva-Santos, B.. 2013. "Protective role of the inflammatory CCR2/CCL2 chemokine pathway through recruitment of type 1 cytotoxic ¿d T lymphocytes to tumor beds". Journal of Immunology 190 (12): 6673-6680. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879112769&partnerID=MN8TOARS.
    10.4049/jimmunol.1300434
  21. Rodrigues, R.; Grosso, A.R.; Moita, L.. 2013. "Genome-Wide Analysis of Alternative Splicing during Dendritic Cell Response to a Bacterial Challenge". PLoS ONE 8 (4). http://www.scopus.com/inward/record.url?eid=2-s2.0-84876265387&partnerID=MN8TOARS.
    10.1371/journal.pone.0061975
  22. Carvalho, S.; Raposo, A.C.; Martins, F.B.; Grosso, A.R.; Sridhara, S.C.; Rino, J.; Carmo-Fonseca, M.; De Almeida, S.F.. 2013. "Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription". Nucleic Acids Research 41 (5): 2881-2893. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876365300&partnerID=MN8TOARS.
    10.1093/nar/gks1472
  23. Schmolka, N.; Serre, K.; Grosso, A.R.; Rei, M.; Pennington, D.J.; Gomes, A.Q.; Silva-Santos, B.. 2013. "Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory ¿d T cell subsets". Nature Immunology 14 (10): 1093-1100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886723991&partnerID=MN8TOARS.
    10.1038/ni.2702
  24. Grosso, A.R.; De Almeida, S.F.; Braga, J.; Carmo-Fonseca, M.. 2012. "Dynamic transitions in RNA polymerase II density profiles during transcription termination". Genome Research 22 (8): 1447-1456. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864577725&partnerID=MN8TOARS.
    10.1101/gr.138057.112
  25. De Almeida, S.F.; Grosso, A.R.; Koch, F.; Fenouil, R.; Carvalho, S.; Andrade, J.; Levezinho, H.; et al. 2011. "Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36". Nature Structural and Molecular Biology 18 (9): 977-983. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052445151&partnerID=MN8TOARS.
    10.1038/nsmb.2123
  26. Gomes, A.Q.; Correia, D.V.; Grosso, A.R.; Lança, T.; Ferreira, C.; Lacerda, J.F.; Barata, J.T.; da Silva, M.G.; Silva-Santos, B.. 2010. "Identification of a panel of ten cell surface protein antigens associated with immunotargeting of leukemias and lymphomas by peripheral blood ¿d t cells". Haematologica 95 (8): 1397-1404. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956032245&partnerID=MN8TOARS.
    10.3324/haematol.2009.020602
  27. Mollet, I.G.; Ben-Dov, C.; Felício-Silva, D.; Grosso, A.R.; Eleutério, P.; Alves, R.; Staller, R.; Silva, T.S.; Carmo-Fonseca, M.. 2010. "Unconstrained mining of transcript data reveals increased alternative splicing complexity in the human transcriptome". Nucleic Acids Research 38 (14): 4740-4754. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955793696&partnerID=MN8TOARS.
    10.1093/nar/gkq197
  28. Albuquerque, S.S.; Carret, C.; Grosso, A.R.; Tarun, A.S.; Peng, X.; Kappe, S.H.I.; Prudêncio, M.; Mota, M.M.. 2009. "Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events". BMC Genomics 10. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650520138&partnerID=MN8TOARS.
    10.1186/1471-2164-10-270
  29. Correia, D.V.; D'Orey, F.; Cardoso, B.A.; Lança, T.; Grosso, A.R.; DeBarros, A.; Martins, L.R.; Barata, J.T.; Silva-Santos, B.. 2009. "Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human ¿d T-cells". PLoS ONE 4 (5). http://www.scopus.com/inward/record.url?eid=2-s2.0-66249119050&partnerID=MN8TOARS.
    10.1371/journal.pone.0005657
  30. Grosso, A.R.; Martins, S.; Carmo-Fonseca, M.. 2008. "The emerging role of splicing factors in cancer". EMBO Reports 9 (11): 1087-1093. http://www.scopus.com/inward/record.url?eid=2-s2.0-55549143293&partnerID=MN8TOARS.
    10.1038/embor.2008.189
  31. Grosso, A.R.; Gomes, A.Q.; Barbosa-Morais, N.L.; Caldeira, S.; Thorne, N.P.; Grech, G.; von Lindern, M.; Carmo-Fonseca, M.. 2008. "Tissue-specific splicing factor gene expression signatures". Nucleic Acids Research 36 (15): 4823-4832. http://www.scopus.com/inward/record.url?eid=2-s2.0-50849145126&partnerID=MN8TOARS.
    10.1093/nar/gkn463
  32. Abrantes, P.; Dimopoulos, G.; Grosso, A.R.; do Rosario, V.E.; Silveira, H.. 2008. "Chloroquine mediated modulation of Anopheles gambiae gene expression". PLoS ONE 3 (7). http://www.scopus.com/inward/record.url?eid=2-s2.0-49749121787&partnerID=MN8TOARS.
    10.1371/journal.pone.0002587
  33. Amaral, A.J.; Silva, A.B.; Grosso, A.R.; Chikhi, L.; Bastos-Silveira, C.; Dias, D.. 2007. "Detection of hybridization and species identification in domesticated and wild quails using genetic markers". Folia Zoologica 56 (3): 285-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-36048956045&partnerID=MN8TOARS.
  34. Grosso, A.R.; Bastos-Silveira, C.; Coelho, M.M.; Dias, D.. 2006. "Columba palumbus Cyt b-like Numt sequence: Comparison with functional homologue and the use of universal primers". Folia Zoologica 55 (2): 131-144. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746876314&partnerID=MN8TOARS.
Thesis / Dissertation
  1. Grosso, Ana Rita Fialho, 1979-; Fonseca, M. Carmo, 1959-; Tavaré, Simon. 2009. "New insights into alternative splicing using microarray technology". PhD. http://catalogo.ul.pt/F/?func=item-global&doc_library=ULB01&type=03&doc_number=000576074.
  2. Grosso, Ana Rita. 2006. "Statistical Methodologies for the Analysis of DNA Microarray Data". Master.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2017 - 2018 Association of DNA modifications with somatic mutations in cancer
Supervisor of João Sousa
 Bioquímica (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2017 Depicting epigenetic mechanisms involved in the regulation of pseudogene expression
Supervisor of Ana Margarida Ferreira
 Biologia Molecular e Genética (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2015 Assessing Pseudogene Expression during Neural Differentiation by RNA-seq
Supervisor of Luis Simões
 Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2015 LincRNA profile in clear cell Renal Cell Carcinoma using RNA-seq data
Supervisor of Ioana Posa
 Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2014 Genome-wide profiling of RNA polymerase II and associated co- transcriptional processes using advanced NET-seq data
Supervisor
 Bioinformática e Biologia Computacional
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2014 LincRNA's Profile in SETD2 Downregulated Cells
Supervisor of Joana Tavares
 Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2013 Study of the role of SETD2 mutations in clear renal Cell Carcinoma (ccRCC)
Co-supervisor of Catarina de Almeida
 Bioestatística (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2013 Intragenic Initiation in SETD2 deficient cells
Co-supervisor of Miguel Pereira
 Bioestatística (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2020/07/06 - 2020/07/10 EMBO Practical Course on "Deciphering tumour heterogeneity and evolution by integration of multi-omics data". This course aims to provide practical insights for cancer researchers regarding the potentials and challenges of using high throughput sequencing to estimate intra-tumoral diversity in its multiple facets. This will include the detection of mutational patterns, selection pressures and driver mutations, as well as techniques for the determination of subclonal diversity and clonal evolution. (2020/07/06 - 2020/07/10) (2020/07/06)
Workshop (Co-organisor)

Consulting

Activity description Institution / Organization
2014 - Current Journal Reviewer: Bioinformatics, BMC Bioinformatics, BMC Cancer, BMC Genomics, Epigenomics, Oncotarget.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - Current Molecular Genomics and Evolution Genética Molecular e Biomedicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - Current Applied Computational Biology Genética Molecular e Biomedicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012 - 2015 Computational Biology in Biomedicine Bioinformática e Biologia Computacional (Mestrado integrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2015 Bioinformatics Oncobiologia (Mestrado integrado) Universidade de Lisboa Faculdade de Medicina, Portugal
Distinctions

Award

2017 Pfizer Award
Pfizer Biofarmacêutica Sociedade Unipessoal Lda, Portugal
2011 Pfizer Award
Pfizer Biofarmacêutica Sociedade Unipessoal Lda, Portugal

Other distinction

2018 FCT CEEC individual
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2014 FCT Investigator
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2010 FCT Post-Doctoral Fellowship
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2006 PhD Fellowship
Fundação para a Ciência e a Tecnologia, I.P., Portugal